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Identification of four chromosomal loci determining obesity in a multifactorial mouse model.

C H Warden, … , M J Pace, A J Lusis

C H Warden, … , M J Pace, A J Lusis

Published April 1, 1995
Citation Information: J Clin Invest. 1995;95(4):1545-1552. https://doi.org/10.1172/JCI117827.

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Pulmonary Effects of Adjusting Tidal Volume to Actual or Ideal Body Weight in Ventilated Obese Mice E Guivarch, G Voiriot, A Rouzé, S Kerbrat, JT Nhieu, P Montravers, B Maitre, AM Dessap, M Desmard, J Boczkowski	Scientific Reports	2018
Genetics of metabolic syndrome: potential clues from wild-derived inbred mouse strains S Karunakaran, SM Clee	Physiological genomics	2018
Chow fed UC Davis strain female Lepr fatty Zucker rats exhibit mild glucose intolerance, hypertriglyceridemia, and increased urine volume, all reduced by a Brown Norway strain chromosome 1 congenic donor region CH Warden, A Bettaieb, E Min, JS Fisler, FG Haj, JS Stern, CM Stover	PloS one	2017
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Four out of eight genes in a mouse chromosome 7 congenic donor region are candidate obesity genes KA Sarahan, JS Fisler, CH Warden	Physiological genomics	2011
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Single QTL effects, epistasis, and pleiotropy account for two-thirds of the phenotypic F(2) variance of growth and obesity in DU6i x DBA/2 mice GA Brockmann, J Kratzsch, CS Haley, U Renne, M Schwerin, S Karle	Genome research	2000
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Test of candidate gene-quantitative trait locus association applied to fatness in mice PD +, KH Morris+, A Ishikawa+, VM Falconer, F Oliver+	Heredity	1998
Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression T Lifsted, TL Voyer, M Williams, W Muller, A Klein-Szanto, KH Buetow, KW Hunter	International Journal of Cancer	1998
Quantitative trait loci affecting body weight and fatness from a mouse line selected for extreme high growth GA Brockmann, CS Haley, U Renne, SA Knott, M Schwerin	Genetics	1998
Diet-induced changes in uncoupling proteins in obesity-prone and obesity-resistant strains of mice RS Surwit, S Wang, AE Petro, D Sanchis, S Raimbault, D Ricquier, S Collins	Proceedings of the National Academy of Sciences	1998
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Complex genetic control of HDL levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism D Machleder, B Ivandic, C Welch, L Castellani, K Reue, AJ Lusis	Journal of Clinical Investigation	1997
Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q AV Lembertas, L Pérusse, YC Chagnon, JS Fisler, CH Warden, DA Purcell-Huynh, FT Dionne, J Gagnon, A Nadeau, AJ Lusis, C Bouchard	Journal of Clinical Investigation	1997
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Obesity QTLs on Mouse Chromosomes 2 and 17 BA Taylor, SJ Phillips	Genomics	1997
Integrated Methods to Solve the Biological Basis of Common Diseases CH Warden, JS Fisler	Methods	1997
A new class of obesity genes encodes leukocyte adhesion receptors ZM Dong, JC Gutierrez-Ramos, A Coxon, TN Mayadas, DD Wagner	Proceedings of the National Academy of Sciences	1997
Suggestive Linkages Between Markers on Human 1p32-p22 and Body Fat and Insulin Levels in the Québec Family Study YC Chagnon, L Pérusse, M Lamothe, M Chagnon, A Nadeau, FT Dionne, J Gagnon, WK Chung, RL Leibel, C Bouchard	Obesity research	1997
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The Molecular Genetics of Rodent Single Gene Obesities RL Leibel, WK Chung, SC Chua	The Journal of biological chemistry	1997
Uncoupling Protein-3 Is a Mediator of Thermogenesis Regulated by Thyroid Hormone, β3-Adrenergic Agonists, and Leptin DW Gong, Y He, M Karas, M Reitman	The Journal of biological chemistry	1997
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Sensitivity to dietary obesity linked to a locus on Chromosome 15 in a CAST/Ei × C57BL/6J F2 intercross B York, K Lei, DB West	Mammalian Genome	1996
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