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Citations to this article

Evidence for a protective role of pulmonary surfactant protein D (SP-D) against influenza A viruses.
K L Hartshorn, … , D Chang, K Sastry
K L Hartshorn, … , D Chang, K Sastry
Published July 1, 1994
Citation Information: J Clin Invest. 1994;94(1):311-319. https://doi.org/10.1172/JCI117323.
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Evidence for a protective role of pulmonary surfactant protein D (SP-D) against influenza A viruses.

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Abstract

We tested the hypothesis that pulmonary surfactant-associated lectins--surfactant proteins A and D (SP-A, and -D)--contribute to initial protective mechanisms against influenza A viruses (IAVs). SP-D potently inhibited hemagglutination activity of several strains of IAV as well as causing viral aggregation. SP-D enhanced neutrophil binding of IAV and neutrophil respiratory burst responses to the virus. Neutrophil dysfunction resulting from IAV exposure was diminished when the virus was pre-incubated with SP-D. Each of these effects was mediated by the calcium-dependent carbohydrate-binding property of SP-D. Native SP-D preparations of both human and rat origin, as well as recombinant rat SP-D, had similar activity. SP-A also inhibited IAV hemagglutination activity. We have previously reported that related mammalian serum lectins (mannose-binding lectin [MBL] and conglutinin) have similar effects. SP-D was at least 10-fold more potent at causing hemagglutination inhibition than were SP-A or MBL. SP-D was shown to contribute to potent anti-IAV activity of human bronchoalveolar lavage fluid. These results suggest that SP-D--alone, and in conjunction with SP-A and phagocytic cells--constitutes an important component of the natural immune response to IAV infection within the respiratory tract.

Authors

K L Hartshorn, E C Crouch, M R White, P Eggleton, A I Tauber, D Chang, K Sastry

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The Journal of biological chemistry 2011
Myeloperoxidase-dependent inactivation of surfactant protein D in vitro and in vivo
EC Crouch, TO Hirche, B Shao, R Boxio, J Wartelle, R Benabid, B McDonald, J Heinecke, S Matalon, A Belaaouaj
The Journal of biological chemistry 2010
Critical Role of Airway Macrophages in Modulating Disease Severity during Influenza Virus Infection of Mice
MD Tate, DL Pickett, N van Rooijen, AG Brooks, PC Reading
Journal of virology 2010
Segmental Allergen Challenge Alters Multimeric Structure and Function of Surfactant Protein D in Humans
EN Atochina-Vasserman, C Winkler, H Abramova, F Schaumann, N Krug, AJ Gow, MF Beers, JM Hohlfeld
American journal of respiratory and critical care medicine 2010
Increasing Antiviral Activity of Surfactant Protein D Trimers By Introducing Residues From Bovine Serum Collectins: Dissociation of mannan-binding and antiviral activity
KL Hartshorn, MR White, K Smith, G Sorensen, Y Kuroki, U Holmskov, J Head, EC Crouch
Scandinavian Journal of Immunology 2010
Microbial Glycobiology
T Kohler, G Xia, E Kulauzovic, A Peschel
Microbial Glycobiology 2010
Pandemic H1N1 influenza A viruses are resistant to the antiviral activities of innate immune proteins of the collectin and pentraxin superfamilies
ER Job, YM Deng, MD Tate, B Bottazzi, EC Crouch, MM Dean, A Mantovani, AG Brooks, PC Reading
Journal of immunology (Baltimore, Md. : 1950) 2010
El papel de la inmunidad innata en las infecciones gripales humanas
J Reina
Vacunas 2010
Viral aggregating and opsonizing activity in collectin trimers
KL Hartshorn, MR White, T Tecle, G Sorensen, U Holmskov, EC Crouch
American journal of physiology. Lung cellular and molecular physiology 2010
Monoclonal antibody-assisted structure-function analysis of the carbohydrate recognition domain of surfactant protein D
KL Hartshorn, MR White, M Rynkiewicz, G Sorensen, U Holmskov, J Head, EC Crouch
American journal of physiology. Lung cellular and molecular physiology 2010
Review: Defensins and cathelicidins in lung immunity
N Palaniyar, T Tecle, S Tripathi, KL Hartshorn
Innate immunity 2010
Insight into the Dynamic Interaction of Different Carbohydrates with Human Surfactant Protein D: Molecular Dynamics Simulations
J Zhang, Q Zheng, H Zhang
The Journal of Physical Chemistry B 2010
Modification of surfactant protein D by reactive oxygen-nitrogen intermediates is accompanied by loss of aggregating activity, in vitro and in vivo
S Matalon, K Shrestha, M Kirk, S Waldheuser, B McDonald, K Smith, Z Gao, A Belaaouaj, EC Crouch
The FASEB Journal 2009
Interactions of α-, β-, and θ-Defensins with Influenza A Virus and Surfactant Protein D
M Doss, MR White, T Tecle, D Gantz, EC Crouch, G Jung, P Ruchala, AJ Waring, RI Lehrer, KL Hartshorn
Journal of immunology (Baltimore, Md. : 1950) 2009
Human defensins and LL-37 in mucosal immunity
M Doss, MR White, T Tecle, KL Hartshorn
Journal of leukocyte biology 2009
Multiple components contribute to ability of saliva to inhibit influenza viruses
MR White, EJ Helmerhorst, A Ligtenberg, M Karpel, T Tecle, WL Siqueira, FG Oppenheim, KL Hartshorn
Oral Microbiology and Immunology 2009
Elevated Plasma Surfactant Protein D (SP-D) Levels and a Direct Correlation with Anti-severe Acute Respiratory Syndrome Coronavirus-specific IgG Antibody in SARS Patients
YP Wu, ZH Liu, R Wei, SD Pan, NY Mao, B Chen, JJ Han, FS Zhang, U Holmskov, ZL Xia, PG de Groot, KB Reid, WB Xu, GL Sorensen
Scandinavian Journal of Immunology 2009
Enhancement of antiviral activity of collectin trimers through cross-linking and mutagenesis of the carbohydrate recognition domain
MR White, P Boland, T Tecle, D Gantz, G Sorenson, I Tornoe, U Holmskov, B McDonald, EC Crouch, KL Hartshorn
Journal of Innate Immunity 2009
Target Pattern Recognition in Innate Immunity
U Kishore
2009
Protective role of the lung collectins surfactant protein A and surfactant protein D in airway inflammation
A Haczku
Journal of Allergy and Clinical Immunology 2008
Innate Immunity in the Paranasal Sinuses: A Review of Nasal Host Defenses
EH Ooi, PJ Wormald, LW Tan
American journal of rhinology 2008
Review: Surfactant protein D: A lung specific biomarker in COPD?
DD Sin, PS Pahlavan, SF Man
Therapeutic advances in respiratory disease 2008
Porcine plasma ficolin binds and reduces infectivity of porcine reproductive and respiratory syndrome virus (PRRSV) in vitro
ND Keirstead, C Lee, D Yoo, AS Brooks, MA Hayes
Antiviral Research 2008
Innate sensors of influenza virus: clues to developing better intranasal vaccines
T Ichinohe, A Iwasaki, H Hasegawa
Expert Review of Vaccines 2008
Innate immunity to influenza virus: implications for future therapy
MR White, M Doss, P Boland, T Tecle, KL Hartshorn
Expert Review of Clinical Immunology 2008
Role of viral hemagglutinin glycosylation in anti-influenza activities of recombinant surfactant protein D
KL Hartshorn, R Webby, MR White, T Tecle, C Pan, S Boucher, RJ Moreland, EC Crouch, RK Scheule
Respiratory Research 2008
Antiviral activity of the long chain pentraxin PTX3 against influenza viruses
PC Reading, S Bozza, B Gilbertson, M Tate, S Moretti, ER Job, EC Crouch, AG Brooks, LE Brown, B Bottazzi, L Romani, A Mantovani
Journal of immunology (Baltimore, Md. : 1950) 2008
Multimerization of Surfactant Protein D, but Not Its Collagen Domain, Is Required for Antiviral and Opsonic Activities Related to Influenza Virus
M White, P Kingma, T Tecle, N Kacak, B Linders, J Heuser, E Crouch, K Hartshorn
Journal of immunology (Baltimore, Md. : 1950) 2008
Pulmonary Surfactant Protein D Binds MD-2 through the Carbohydrate Recognition Domain
X Nie, C Nishitani, M Yamazoe, S Ariki, M Takahashi, T Shimizu, H Mitsuzawa, K Sawada, K Smith, E Crouch, H Nagae, H Takahashi, Y Kuroki
Biochemistry 2008
Pattern Recognition Molecule Mindin Promotes Intranasal Clearance of Influenza Viruses
W Jia, H Li, YW He
Journal of immunology (Baltimore, Md. : 1950) 2008
Current Topics in Innate Immunity
JD Lambris
2007
Current Topics in Innate Immunity
JD Lambris
2007
Current Topics in Innate Immunity
JD Lambris
2007
Current Topics in Innate Immunity
JD Lambris
2007
Current Topics in Innate Immunity
JD Lambris
2007
Current Topics in Innate Immunity
JD Lambris
2007
Current Topics in Innate Immunity
JD Lambris
2007
Current Topics in Innate Immunity
JD Lambris
2007
Current Topics in Innate Immunity
JD Lambris
2007
Current Topics in Innate Immunity
JD Lambris
2007
Human Neutrophil Defensins Increase Neutrophil Uptake of Influenza A Virus and Bacteria and Modify Virus-Induced Respiratory Burst Responses
T Tecle, MR White, D Gantz, EC Crouch, KL Hartshorn
Journal of immunology (Baltimore, Md. : 1950) 2007
Virus glycosylation: role in virulence and immune interactions
DJ Vigerust, VL Shepherd
Trends in Microbiology 2007
Inhibition of hemagglutination activity of influenza A viruses by SP-A1 and SP-A2 variants expressed in CHO cells
AN Mikerov, M White, K Hartshorn, G Wang, J Floros
Medical Microbiology and Immunology 2007
Pulmonary collectins in innate immunity of the lung
Y Kuroki, M Takahashi, C Nishitani
Cellular Microbiology 2007
Inhibition of influenza viral neuraminidase activity by collectins
T Tecle, MR White, EC Crouch, KL Hartshorn
Archives of Virology 2007
Effects of surfactant protein D on growth, adhesion and epithelial invasion of intestinal Gram-negative bacteria
A Hogenkamp, MV Herías, PC Tooten, EJ Veldhuizen, HP Haagsman
Molecular Immunology 2007
Reduced influenza viral neutralizing activity of natural human trimers of surfactant protein D
KL Hartshorn, MR White, T Tecle, I Tornoe, GL Sorensen, EC Crouch, U Holmskov
Respiratory Research 2007
Diesel Exhaust Enhanced Susceptibility to Influenza Infection is Associated with Decreased Surfactant Protein Expression
J Ciencewicki, K Gowdy, QT Krantz, WP Linak, L Brighton, MI Gilmour, I Jaspers
Inhalation Toxicology 2007
Impact of neutrophils on antiviral activity of human bronchoalveolar lavage fluid
MR White, T Tecle, EC Crouch, KL Hartshorn
American journal of physiology. Lung cellular and molecular physiology 2007
Anti-Influenza A Virus Activities of Mannan-Binding Lectins and Bovine Conglutinin
T KAWAI, T KASE, Y SUZUKI, S EDA, T SAKAMOTO, K OHTANI, N WAKAMIYA
Journal of Veterinary Medical Science 2007
Current Topics in Innate Immunity
JD Lambris
2007
Innate Defense against Influenza A Virus: Activity of Human Neutrophil Defensins and Interactions of Defensins with Surfactant Protein D
KL Hartshorn, MR White, T Tecle, U Holmskov, EC Crouch
Journal of immunology (Baltimore, Md. : 1950) 2006
Search for additional influenza virus to cell interactions
EM Rapoport, LV Mochalova, HJ Gabius, J Romanova, NV Bovin
Glycoconjugate Journal 2006
Surfactant proteins SP-A and SP-D: Structure, function and receptors
U Kishore, TJ Greenhough, P Waters, AK Shrive, R Ghai, MF Kamran, AL Bernal, KB Reid, T Madan, T Chakraborty
Molecular Immunology 2006
Influenza A Viruses Upregulate Neutrophil Toll-Like Receptor 2 Expression and Function
RM Lee, MR White, KL Hartshorn
Scandinavian Journal of Immunology 2006
Characterization and expression sites of newly identified chicken collectins
A Hogenkamp, M Eijk, A Dijk, AJ van Asten, EJ Veldhuizen, HP Haagsman
Molecular Immunology 2006
Correction of Pulmonary Abnormalities in Sftpd-/- Mice Requires the Collagenous Domain of Surfactant Protein D
PS Kingma, L Zhang, M Ikegami, K Hartshorn, FX McCormack, JA Whitsett
The Journal of biological chemistry 2006
Effect of Lung Surfactant Collectins on Bronchoalveolar Macrophage Interaction with Blastomyces dermatitidis : Inhibition of Tumor Necrosis Factor Alpha Production by Surfactant Protein D
M Lekkala, AM LeVine, MJ Linke, EC Crouch, B Linders, E Brummer, DA Stevens
Infection and immunity 2006
Human Pulmonary Surfactant Protein D Binds the Extracellular Domains of Toll-like Receptors 2 and 4 through the Carbohydrate Recognition Domain by a Mechanism Different from Its Binding to Phosphatidylinositol and Lipopolysaccharide
M Ohya, C Nishitani, H Sano, C Yamada, H Mitsuzawa, T Shimizu, T Saito, K Smith, E Crouch, Y Kuroki
Biochemistry 2006
A Common Polymorphism in the SFTPD Gene Influences Assembly, Function, and Concentration of Surfactant Protein D
R Leth-Larsen, P Garred, H Jensenius, J Meschi, K Hartshorn, J Madsen, I Tornoe, HO Madsen, G Sørensen, E Crouch, U Holmskov
Journal of immunology (Baltimore, Md. : 1950) 2005
Variations in Helicobacter pylori Lipopolysaccharide To Evade the Innate Immune Component Surfactant Protein D
W Khamri, AP Moran, ML Worku, QN Karim, MM Walker, H Annuk, JA Ferris, BJ Appelmelk, P Eggleton, KB Reid, MR Thursz
Infection and immunity 2005
Noncapsulated Klebsiella pneumoniae bearing mannose-containing O antigens is rapidly eradicated from mouse lung and triggers cytokine production by macrophages following opsonization with surfactant protein D
E Kostina, I Ofek, E Crouch, R Friedman, L Sirota, G Klinger, H Sahly, Y Keisari
Infection and immunity 2005
Novel strategies for prevention and treatment of influenza
R Kandel, KL Hartshorn
Expert Opinion on Therapeutic Targets 2005
Innate immune response to adenovirus
Shoab A Nazir, Jordan P Metcalf
Journal of Investigative Medicine 2005
Role of surfactant protein D (SP-D) in innate immunity in the gastric mucosa: evidence of interaction with Helicobacter pylori lipopolysaccharide
AP Moran, W Khamri, MM Walker, MR Thursz
Journal of Endotoxin Research 2005
Respiratory innate immune proteins differentially modulate the neutrophil respiratory burst response to influenza A virus
MR White, E Crouch, J Vesona, PJ Tacken, JJ Batenburg, R Leth-Larsen, U Holmskov, KL Hartshorn
American journal of physiology. Lung cellular and molecular physiology 2005
Cooperative anti-influenza activities of respiratory innate immune proteins and neuraminidase inhibitor
MR White, E Crouch, M Eijk, M Hartshorn, L Pemberton, I Tornoe, U Holmskov, KL Hartshorn
American journal of physiology. Lung cellular and molecular physiology 2005
Surfactant protein D binds to human immunodeficiency virus (HIV) envelope protein gp120 and inhibits HIV replication
J Meschi, EC Crouch, P Skolnik, K Yahya, U Holmskov, R Leth-Larsen, I Tornoe, T Tecle, MR White, KL Hartshorn
Journal of General Virology 2005
Salivary agglutinin and lung scavenger receptor cysteine-rich glycoprotein 340 have broad anti-influenza activities and interactions with surfactant protein D that vary according to donor source and sialylation
KL Hartshorn, A Ligtenberg, MR White, M van Eijk, M Hartshorn, L Pemberton, U Holmskov, E Crouch
Biochemical Journal 2005
Effective targeting of pathogens to neutrophils via chimeric surfactant protein D/anti-CD89 protein
PJ Tacken, KL Hartshorn, MR White, C Kooten, JG van de Winkel, KB Reid, JJ Batenburg
Journal of immunology (Baltimore, Md. : 1950) 2004
Pulmonary Collectins Modulate Strain-Specific Influenza A Virus Infection and Host Responses
S Hawgood, C Brown, J Edmondson, A Stumbaugh, L Allen, J Goerke, H Clark, F Poulain
Journal of virology 2004
Collectins
JK van de Wetering, LM van Golde, JJ Batenburg
European Journal of Biochemistry 2004
Interactions of Influenza A Virus with Sialic Acids Present on Porcine Surfactant Protein D
M Eijk, MR White, JJ Batenburg, AB Vaandrager, LM van Golde, HP Haagsman, KL Hartshorn
American journal of respiratory cell and molecular biology 2004
Degradation of Pulmonary Surfactant Protein D by Pseudomonas aeruginosa Elastase Abrogates Innate Immune Function
JF Alcorn, JR Wright
The Journal of biological chemistry 2004
The Innate Immune Response to Infection
SH Kaufmann, R Medzhitov, S Gordon
2004
Lupus-Prone Mice Have an Abnormal Response to Thioglycolate and an Impaired Clearance of Apoptotic Cells
PK Potter, J Cortes-Hernandez, P Quartier, M Botto, MJ Walport
Journal of immunology (Baltimore, Md. : 1950) 2003
The Cochrane Database of Systematic Reviews
L Hooper, C Bartlett, SG Davey, S Ebrahim
The Cochrane Database of Systematic Reviews 2003
Surfactant protein D (SP-D) serum levels in patients with community-acquired pneumonia☆☆This work was supported by the Danish Medical Research Council, an EU grant, contract number: QLK2-CT-2000-0035; the Novo Nordisk Foundation; Fonden til Lægevidenskabens Fremme; Ingemann O. Bucks Foundation and the Benzon Foundation
R Leth-Larsen, C Nordenbaek, I Tornoe, V Moeller, A Schlosser, C Koch, B Teisner, P Junker, U Holmskov
Clinical Immunology 2003
Surfactant protein D-mediated aggregation of Pneumocystis carinii impairs phagocytosis by alveolar macrophages
SJ Yong, Z Vuk-Pavlovic, JE Standing, EC Crouch, AH Limper
Infection and immunity 2003
Lung and salivary scavenger receptor glycoprotein-340 contribute to the host defense against influenza A viruses
KL Hartshorn, MR White, T Mogues, T Ligtenberg, E Crouch, U Holmskov
American journal of physiology. Lung cellular and molecular physiology 2003
The Macrophage as Therapeutic Target
S Gordon
2003
Lupus-Prone Mice Have an Abnormal Response to Thioglycolate and an Impaired Clearance of Apoptotic Cells
PK Potter, J Cortes-Hernandez, P Quartier, M Botto, MJ Walport
Journal of immunology (Baltimore, Md. : 1950) 2003
Porcine Pulmonary Collectins Show Distinct Interactions with Influenza A Viruses: Role of the N -Linked Oligosaccharides in the Carbohydrate Recognition Domain
M van Eijk, MR White, EC Crouch, JJ Batenburg, AB Vaandrager, LM van Golde, HP Haagsman, KL Hartshorn
Journal of immunology (Baltimore, Md. : 1950) 2003
Molecular Cloning of Mouse Collectin Liver 1
T KAWAI, Y SUZUKI, S EDA, T KASE, K OHTANI, Y SAKAI, H KESHI, A FUKUOH, T SAKAMOTO, M NOZAKI, NG COPELAND, NA JENKINS, N WAKAMIYA
Bioscience, Biotechnology, and Biochemistry 2002
Contributions of the N- and C-terminal domains of surfactant protein d to the binding, aggregation, and phagocytic uptake of bacteria
KL Hartshorn, MR White, EC Crouch
Infection and immunity 2002
Distinctive anti-influenza properties of recombinant collectin 43
KL Hartshorn, U Holmskov, S Hansen, P Zhang, J Meschi, T Mogues, MR White, EC Crouch
Biochemical Journal 2002
Surfactant protein-A--deficient mice display an exaggerated early inflammatory response to a beta-resistant strain of influenza A virus
G Li, J Siddiqui, M Hendry, J Akiyama, J Edmondson, C Brown, L Allen, S Levitt, F Poulain, S Hawgood
American journal of respiratory cell and molecular biology 2002
Distinct Roles for Lung Collectins in Pulmonary Host Defense
VL Shepherd
American journal of respiratory cell and molecular biology 2002
Absence of SP-A modulates innate and adaptive defense responses to pulmonary influenza infection
AM LeVine, K Hartshorn, J Elliott, J Whitsett, T Korfhagen
American journal of physiology. Lung cellular and molecular physiology 2002
Human Surfactant Protein D (SP-D) Binds Mycoplasma pneumoniae by High Affinity Interactions with Lipids
H Chiba, S Pattanajitvilai, AJ Evans, RJ Harbeck, DR Voelker
The Journal of biological chemistry 2002
Complementation of Pulmonary Abnormalities in SP-D(−/−) Mice with an SP-D/Conglutinin Fusion Protein
L Zhang, KL Hartshorn, EC Crouch, M Ikegami, JA Whitsett
The Journal of biological chemistry 2002
Glycomicrobiology
RJ Doyle
2002
Pulmonary collectins and innate host defense of the lung
AM LeVine, JA Whitsett
Microbes and Infection 2001
The present status of exogenous surfactant for the newborn
AE Curley, HL Halliday
Early Human Development 2001
Lectins in innate host defence against influenza virus
EM Anders, PC Reading, JL Miller
International Congress Series 2001
Surfactant proteins a and d and pulmonary host defense
JC Clark, SE Wert, CJ Bachurski, MT Stahlman, BR Stripp, TE Weaver, JA Whitsett
Annual Review of Physiology 2001
Surfactant protein D enhances clearance of influenza A virus from the lung in vivo
AM LeVine, JA Whitsett, KL Hartshorn, EC Crouch, TR Korfhagen
Journal of immunology (Baltimore, Md. : 1950) 2001
Surfactant proteins a and d and pulmonary host defense
JC Clark, SE Wert, CJ Bachurski, MT Stahlman, BR Stripp, TE Weaver, JA Whitsett
Annual Review of Physiology 2001
Carbohydrate Recognition Domain of Surfactant Protein D Mediates Interactions with Pneumocystis carinii Glycoprotein A
Z Vuk-Pavlovic, JE Standing, EC Crouch, AH Limper
American journal of respiratory cell and molecular biology 2001
Alveolar Macrophages, Surfactant Lipids, and Surfactant Protein B Regulate the Induction of Immune Responses via the Airways
JF van Iwaarden, E Claassen, SH Jeurissen, HP Haagsman, G Kraal
American journal of respiratory cell and molecular biology 2001
Localization and Functions of SP-A and SP-D at Mucosal Surfaces
BA van Rozendaal, LM van Golde, HP Haagsman
Pediatric Pathology & Molecular Medicine 2001
The Membrane-type Collectin CL-P1 Is a Scavenger Receptor on Vascular Endothelial Cells
K Ohtani, Y Suzuki, S Eda, T Kawai, T Kase, H Keshi, Y Sakai, A Fukuoh, T Sakamoto, H Itabe, T Suzutani, M Ogasawara, I Yoshida, N Wakamiya
The Journal of biological chemistry 2001
Activity of Pulmonary Surfactant Protein-D (SP-D) in Vivo Is Dependent on Oligomeric Structure
L Zhang, M Ikegami, EC Crouch, TR Korfhagen, JA Whitsett
The Journal of biological chemistry 2001
Molecular Biology of Acute Lung Injury
HR Wong, TP Shanley
2001
Prophylaxis and Treatment of Influenza Virus Infection:
R Kandel, KL Hartshorn
BioDrugs 2001
Pulmonary alveolar proteinosis: clinical aspects and current concepts on pathogenesis
PL Shah, D Hansell, PR Lawson, KB Reid, C Morgan
Thorax 2000
Mechanism of binding of surfactant protein D to influenza A viruses: importance of binding to haemagglutinin to antiviral activity
KL Hartshorn, MR White, DR Voelker, J Coburn, K Zaner, EC Crouch
Biochemical Journal 2000
Collectins and collectin receptors in innate immunity
UL Holmskov
APMIS 2000
Pulmonary surfactant in innate immunity and the pathogenesis of tuberculosis
JS Ferguson, LS Schlesinger
Tubercle and Lung Disease 2000
Enhanced antiviral and opsonic activity of a human mannose-binding lectin and surfactant protein D chimera
MR White, E Crouch, D Chang, K Sastry, N Guo, G Engelich, K Takahashi, RA Ezekowitz, KL Hartshorn
Journal of immunology (Baltimore, Md. : 1950) 2000
Surfactant protein-D and pulmonary host defense
EC Crouch
Respiratory Research 2000
Surfactant treatment impairs gas exchange in a canine model of acute lung injury:
JB Waugh, TB Holt, LE Olson, JE Gadek, TL Clanton
Critical Care Medicine 2000
Localization of Lung Surfactant Protein D on Mucosal Surfaces in Human Tissues
J Madsen, A Kliem, I Tornøe, K Skjødt, C Koch, U Holmskov
Journal of immunology (Baltimore, Md. : 1950) 2000
Porcine Lung Surfactant Protein D: Complementary DNA Cloning, Chromosomal Localization, and Tissue Distribution
M van Eijk, HP Haagsman, T Skinner, A Archibold, KB Reid, PR Lawson
Journal of immunology (Baltimore, Md. : 1950) 2000
Aerosolized endotoxin is immediately bound by pulmonary surfactant protein D in vivo
BA van Rozendaal, CH van de Lest, M Eijk, LM van Golde, WF Voorhout, HP van Helden, HP Haagsman
Biochimica et Biophysica Acta 1999
Chronic Lung Disease in Early Infancy
D Riley
Chronic Lung Disease in Early Infancy 1999
Surfactant Protein D Stimulates Phagocytosis of Pseudomonas aeruginosa by Alveolar Macrophages
CI Restrepo, Q Dong, J Savov, WI Mariencheck, JR Wright
American journal of respiratory cell and molecular biology 1999
Surfactant Protein Levels in Severe Respiratory Syncytial Virus Infection
MH Kerr, JY Paton
American journal of respiratory and critical care medicine 1999
Brief Exposure to 95% Oxygen Alters Surfactant Protein D and mRNA in Adult Rat Alveolar and Bronchiolar Epithelium
AO Aderibigbe, RF Thomas, RR Mercer, RL Auten
American journal of respiratory cell and molecular biology 1999
Recombinant SP-D carbohydrate recognition domain is a chemoattractant for human neutrophils
GZ Cai, GL Griffin, R M., WJ Longmore, MA Moxley
American journal of physiology. Lung cellular and molecular physiology 1999
Molecular Cloning of a Novel Human Collectin from Liver (CL-L1)
K Ohtani, Y Suzuki, S Eda, T Kawai, T Kase, H Yamazaki, T Shimada, H Keshi, Y Sakai, A Fukuoh, T Sakamoto, N Wakamiya
The Journal of biological chemistry 1999
Effects of endotoxin on surfactant protein A and D stimulation of NO production by alveolar macrophages
JR Wright, DF Zlogar, JC Taylor, TM Zlogar, CI Restrepo
American journal of physiology. Lung cellular and molecular physiology 1999
Influenza A Virus Accelerates Neutrophil Apoptosis and Markedly Potentiates Apoptotic Effects of Bacteria
ML Colamussi, MR White, E Crouch, KL Hartshorn
Blood 1999
Binding of Rat and Human Surfactant Proteins A and D to Aspergillus fumigatus Conidia
TR Kozel, MJ Allen, R Harbeck, B Smith, DR Voelker, RJ Mason
Infection and immunity 1999
Increased susceptibility of diabetic mice to influenza virus infection: compromise of collectin-mediated host defense of the lung by glucose?
PC Reading, J Allison, EC Crouch, EM Anders
Journal of virology 1998
Altered surfactant homeostasis and alveolar type II cell morphology in mice lacking surfactant protein D
C Botas, F Poulain, J Akiyama, C Brown, L Allen, J Goerke, J Clements, E Carlson, AM Gillespie, C Epstein, S Hawgood
Proceedings of the National Academy of Sciences 1998
Functional Roles of the Lung Surfactant Proteins SP-A and SP-D in Innate Immunity
KB Reid
Immunobiology 1998
Recombinant rat surfactant-associated protein D inhibits human T lymphocyte proliferation and IL-2 production
T Madan, U Kishore, A Shah, P Eggleton, P Strong, JY Wang, SS Aggrawal, PU Sarma, KB Reid
Journal of immunology (Baltimore, Md. : 1950) 1998
Interactions of surfactant protein D with pathogens, allergens and phagocytes
KB Reid
Biochimica et Biophysica Acta 1998
Recombinant rat surfactant-associated protein D inhibits human T lymphocyte proliferation and IL-2 production
T Madan, U Kishore, A Shah, P Eggleton, P Strong, JY Wang, SS Aggrawal, PU Sarma, KB Reid
Journal of immunology (Baltimore, Md. : 1950) 1998
Collectins and Pulmonary Host Defense
EC Crouch
American journal of respiratory cell and molecular biology 1998
Interactions of surfactant protein A with pathogens
H P Haagsman
Biochimica et Biophysica Acta 1998
Structure, biologic properties, and expression of surfactant protein D (SP-D)
E C Crouch
Biochimica et Biophysica Acta 1998
Surfactant protein A and surfactant protein D in health and disease
RJ Mason, K Greene, DR Voelker
American journal of physiology. Lung cellular and molecular physiology 1998
Analysis of Chimeric Proteins Identifies the Regions in the Carbohydrate Recognition Domains of Rat Lung Collectins That Are Essential for Interactions with Phospholipids, Glycolipids, and Alveolar Type II Cells
H Sano, Y Kuroki, T Honma, Y Ogasawara, H Sohma, DR Voelker, T Akino
The Journal of biological chemistry 1998
Pulmonary surfactant proteins A and D enhance neutrophil uptake of bacteria
KL Hartshorn, E Crouch, MR White, ML Colamussi, A Kakkanatt, B Tauber, V Shepherd, KN Sastry
American journal of physiology. Lung cellular and molecular physiology 1998
Degradation of surfactant protein D by alveolar macrophages
Q Dong, JR Wright
American journal of physiology. Lung cellular and molecular physiology 1998
Principles of Perinatal—Neonatal Metabolism
RM Cowett
1998
Molecular Structures and Interactions of Pulmonary Surfactant Components
J Johansson, T Curstedt
European Journal of Biochemistry 1997
Surfactant protein A, but not surfactant protein D, is an opsonin for influenza A virus phagocytosis by rat alveolar macrophages
CA Benne, B Benaissa-Trouw, JA van Strijp, CA Kraaijeveld, JF van Iwaarden
European Journal of Immunology 1997
Binding of pulmonary surfactant proteins A and D to Aspergillus fumigatus conidia enhances phagocytosis and killing by human neutrophils and alveolar macrophages
T Madan, P Eggleton, U Kishore, P Strong, SS Aggrawal, PU Sarma, KB Reid
Infection and immunity 1997
Structure of a truncated human surfactant protein D is less effective in agglutinating bacteria than the native structure and fails to inhibit haemagglutination by influenza A virus
S Eda, Y Suzuki, T Kawai, K Ohtani, T Kase, Y Fujinaga, T Sakamoto, T Kurimura, N Wakamiya
Biochemical Journal 1997
Enzyme-linked immunosorbent assay using F(ab′)2 fragment for the detection of human pulmonary surfactant protein D in sera
H Nagae, H Takahashi, Y Kuroki, Y Honda, A Nagata, Y Ogasawara, S Abe, T Akino
Clinica Chimica Acta 1997
Isolation and Characterization of a New Member of the Scavenger Receptor Superfamily, Glycoprotein-340 (gp-340), as a Lung Surfactant Protein-D Binding Molecule
U Holmskov, P Lawson, B Teisner, I Tornøe, AC Willis, C Morgan, C Koch, KB Reid
The Journal of biological chemistry 1997
Mechanisms of anti-influenza activity of surfactant proteins A and D: comparison with serum collectins
KL Hartshorn, MR White, V Shepherd, K Reid, JC Jensenius, EC Crouch
American journal of physiology. Lung cellular and molecular physiology 1997
Collectin-mediated antiviral host defense of the lung: evidence from influenza virus infection of mice
PC Reading, LS Morey, EC Crouch, EM Anders
Journal of virology 1997
Toxic oxidant species and their impact on the pulmonary surfactant system
E Putman, LM van Golde, HP Haagsman
Lung 1997
Collectin-mediated antiviral host defense of the lung: evidence from influenza virus infection of mice.
Reading PC, Morey LS, Crouch EC, Anders EM
Journal of virology 1997
Binding of pulmonary surfactant proteins A and D to Aspergillus fumigatus conidia enhances phagocytosis and killing by human neutrophils and alveolar macrophages.
Madan T, Eggleton P, Kishore U, Strong P, Aggrawal SS, Sarma PU, Reid KB
Infection and immunity 1997
The collectins in innate immunity
J Epstein, Q Eichbaum, S Sheriff, RA Ezekowitz
Current Opinion in Immunology 1996
Recombinant bovine conglutinin, lacking the N-terminal and collagenous domains, has less conglutination activity but is able to inhibit haemagglutination by influenza A virus
S Eda, Y Suzuki, T Kase, T Kawai, K Ohtani, T Sakamoto, T Kurimura, N Wakamiya
Biochemical Journal 1996
Localization and Developmental Expression of Surfactant Proteins D and A in the Respiratory Tract of the Mouse
CJ Wong, J Akiyama, L Allen, S Hawgood
Pediatric Research 1996
Characterization of Radioiodinated Lung Surfactant Protein a (SP-A) and the Effects of Oxidation on SP-A Quaternary Structure and Activity
GR Stuart, RB Sim, R Malhotra
Experimental Lung Research 1996
Site-directed Mutagenesis of Cys-15 and Cys-20 of Pulmonary Surfactant Protein D: EXPRESSION OF A TRIMERIC PROTEIN WITH ALTERED ANTI-VIRAL PROPERTIES
P Brown-Augsburger, K Hartshorn, D Chang, K Rust, C Fliszar, HG Welgus, EC Crouch
The Journal of biological chemistry 1996
Biosynthesis of Surfactant Protein D: CONTRIBUTIONS OF CONSERVED NH 2 -TERMINAL CYSTEINE RESIDUES AND COLLAGEN HELIX FORMATION TO ASSEMBLY AND SECRETION
P Brown-Augsburger, D Chang, K Rust, EC Crouch
The Journal of biological chemistry 1996
In VitroandIn VivoTransfer and Expression of Human Surfactant SP-A- and SP-B-Associated Protein cDNAs Mediated by Replication-Deficient, Recombinant Adenoviral Vectors
RJ Korst, B Bewig, RG Crystal
Human Gene Therapy 1995
Collectins and viral infection
R Malhotra, RB Sim
Trends in Microbiology 1995
Binding of host collectins to the pathogenic yeast Cryptococcus neoformans: human surfactant protein D acts as an agglutinin for acapsular yeast cells
S Schelenz, R Malhotra, RB Sim, U Holmskov, GJ Bancroft
Infection and immunity 1995
The Role of the Amino-terminal Domain and the Collagenous Region in the Structure and the Function of Rat Surfactant Protein D
Y Ogasawara, DR Voelker
The Journal of biological chemistry 1995
Altered Carbohydrate Recognition Specificity Engineered into Surfactant Protein D Reveals Different Binding Mechanisms for Phosphatidylinositol and Glucosylceramide
Y Ogasawara, DR Voelker
The Journal of biological chemistry 1995

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