E Cersosimo, R L Judd, J M Miles
Title and authors | Publication | Year |
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Agomelatine Mitigates Kidney Damage in Obese Insulin-Resistant Rats by Inhibiting Inflammation and Necroptosis via the TNF-α/NF-ĸB/p-RIPK3 Pathway
Promsan S, Pengrattanachot N, Phengpol N, Sutthasupha P, Thongnak LO, Jaikumkao K, Lungkaphin A |
International Journal of Molecular Sciences | 2025 |
Influence of renal function on the ability of TyG Index to predict all-cause mortality
Li H, Chen W, Lin X, Chen W, Xie T, Chen K, Hou S, Li H |
Lipids in Health and Disease | 2023 |
Insulin-induced mTOR signaling and gluconeogenesis in renal proximal tubules: A mini-review of current evidence and therapeutic potential.
Nakamura M, Satoh N, Horita S, Nangaku M |
Frontiers in pharmacology | 2022 |
Multi-tissue 2H/13C flux analysis reveals reciprocal upregulation of renal gluconeogenesis in hepatic PEPCK-C knockout mice
Mohsin Rahim, Clinton M. Hasenour, Tomasz Bednarski, Curtis C Hughey, David H. Wasserman, Jamey D. Young |
JCI Insight | 2021 |
Sugar or Fat? Renal Tubular Metabolism Reviewed in Health and Disease
LS Gewin |
Nutrients | 2021 |
Resveratrol attenuates dapagliflozin-induced renal gluconeogenesis via activating the PI3K/Akt pathway and suppressing the FoxO1 pathway in type 2 diabetes
X Sun, Z Cao, Y Ma, Y Shao, J Zhang, G Yuan, X Guo |
Food & Function | 2021 |
Phosphoenolpyruvate carboxykinase in urine exosomes reflect impairment in renal gluconeogenesis in early insulin resistance and diabetes
R Sharma, M Kumari, P Prakash, S Gupta, S Tiwari |
American journal of physiology. Renal physiology | 2020 |
Insulin promotes sodium transport but suppresses gluconeogenesis via distinct cellular pathways in human and rat renal proximal tubules
M Nakamura, H Tsukada, G Seki, N Satoh, T Mizuno, W Fujii, S Horita, K Moriya, Y Sato, H Kume, M Nangaku, M Suzuki |
Kidney International | 2019 |
Hormonal, Metabolic and Hemodynamic Adaptations to Glycosuria in Type 2 Diabetes Patients Treated with Sodium-Glucose Co-Transporter Inhibitors
E Cersosimo, JM Miles |
Current diabetes reviews | 2019 |
Insulin receptors in the kidneys in health and disease
S Singh, R Sharma, M Kumari, S Tiwari |
World Journal of Nephrology | 2019 |
Inhibition of NF-κB Reduces Renal Inflammation and Expression of PEPCK in Type 2 Diabetic Mice
Q Liu, L Zhang, W Zhang, Q Hao, W Qiu, Y Wen, H Wang, X Li |
Inflammation | 2018 |
Endogenous Glucose Production and Hormonal Changes in Response to Canagliflozin and Liraglutide Combination Therapy
R Martinez, H Al-Jobori, AM Ali, J Adams, M Abdul-Ghani, C Triplitt, RA DeFronzo, E Cersosimo |
Diabetes | 2018 |
Risk of Hypoglycemia Following Hospital Discharge in Patients With Diabetes and Acute Kidney Injury
AM Hung, ED Siew, OD Wilson, AM Perkins, RA Greevy, J Horner, K Abdel-Kader, SK Parr, CL Roumie, MR Griffin, TA Ikizler, T Speroff, ME Matheny |
Diabetes care | 2018 |
Diabetes Complications, Comorbidities and Related Disorders
E Bonora, R DeFronzo |
2018 | |
Reduced Insulin Receptor Expression Enhances Proximal Tubule Gluconeogenesis: I NSULIN R ECEPTOR AND K IDNEY G LUCONEOGENESIS
G Pandey, K Shankar, E Makhija, A Gaikwad, C Ecelbarger, A Mandhani, A Srivastava, S Tiwari |
Journal of Cellular Biochemistry | 2016 |
Detection of localized changes in the metabolism of hyperpolarized gluconeogenic precursors 13 C-lactate and 13 C-pyruvate in kidney and liver: Localized Changes in Hyperpolarized Lactate Metabolism
C Morze, GY Chang, PE Larson, H Shang, PK Allu, RA Bok, JC Crane, MP Olson, CT Tan, I Marco-Rius, SJ Nelson, J Kurhanewicz, D Pearce, DB Vigneron |
Magnetic Resonance in Medicine | 2016 |
Glucagon sensitivity and clearance in type 1 diabetes: insights from in vivo and in silico experiments
L Hinshaw, A Mallad, CD Man, R Basu, C Cobelli, RE Carter, YC Kudva, A Basu |
American journal of physiology. Endocrinology and metabolism | 2015 |
Comprehensive Physiology
SN Cheuvront, RW Kenefick |
Comprehensive Physiology | 2014 |
Proinsulin C-peptide potentiates the inhibitory action of insulin on glucose synthesis in primary cultured rabbit kidney-cortex tubules: Metabolic studies
M Usarek, AK Jagielski, P Krempa, A Dylewska, A Kiersztan, J Drozak, A Girstun, RA Derlacz, J Bryla |
Biochemistry and Cell Biology | 2014 |
Pathomorphological effects of Alloxan induced acute hypoglycaemia in rabbits
MS Mir, MM Darzi, HM Khan, SA Kamil, AH Sofi, SA Wani |
Alexandria Journal of Medicine | 2013 |
Brenner and Rector's The Kidney
C Brugnara, KU Eckardt |
Brenner and Rector's The Kidney | 2012 |
Kidney: Its impact on glucose homeostasis and hormonal regulation
A Mitrakou |
Diabetes Research and Clinical Practice | 2011 |
Chronic Kidney Disease, Dialysis, and Transplantation
IH de Boer |
Chronic Kidney Disease, Dialysis, and Transplantation | 2010 |
Is There Glucose Production Outside of the Liver and Kidney?
SF Previs, DZ Brunengraber, H Brunengraber |
Annual Review of Nutrition | 2009 |
Insulin Resistance and Diabetes in Chronic Renal Disease
DC Simonson |
Textbook of Nephro-Endocrinology | 2009 |
Textbook of Nephro-Endocrinology
AS Dusso, AJ Brown |
Textbook of Nephro-Endocrinology | 2009 |
How to measure hepatic insulin resistance?
SP Choukem, JF Gautier |
Diabetes & Metabolism | 2008 |
Renal amino acid, fat and glucose metabolism in type 1 diabetic and non-diabetic humans: effects of acute insulin withdrawal
N Moller, MD Jensen, RA Rizza, JC Andrews, KS Nair |
Diabetologia | 2006 |
Contribution of intestine and kidney to glucose fluxes in different nutritional states in rat
G Mithieux, A Gautier-Stein, F Rajas, C Zitoun |
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology | 2006 |
ACTIVE ROLE FOR THE VASCULATURE IN THE DELIVERY OF INSULIN TO SKELETAL MUSCLE
MA Vincent, LH Clerk, S Rattigan, MG Clark, EJ Barrett |
Clinical and Experimental Pharmacology and Physiology | 2005 |
Amino acid and protein metabolism in chronic renal failure
KS Nair |
Journal of Renal Nutrition | 2005 |
Insulin resistance in critically ill patients with acute renal failure
S Basi, LB Pupim, EM Simmons, MT Sezer, Y Shyr, S Freedman, GM Chertow, RL Mehta, E Paganini, J Himmelfarb, TA Ikizler |
American journal of physiology. Renal physiology | 2005 |
Glucose production and substrate cycle activity in a fasting adapted animal, the northern elephant seal
CD Champagne, DS Houser, DE Crocker |
The Journal of experimental biology | 2005 |
Insulin therapy and hypoglycaemia: the size of the problem
CG Fanelli, F Porcellati, S Pampanelli, GB Bolli |
Diabetes/Metabolism Research and Reviews | 2004 |
The metabolic syndrome and uric acid nephrolithiasis: Novel features of renal manifestation of insulin resistance
N Abate, M Chandalia, AV Cabo-Chan, OW Moe, K Sakhaee |
Kidney International | 2004 |
Effects of hyperglycemia, glucagon, and epinephrine on renal glucose release in the conscious dog
SM Gustavson, CA Chu, M Nishizawa, D Neal, B Farmer, Y Yang, EP Donahue, P Flakoll, AD Cherrington |
Metabolism | 2004 |
Fat-induced liver insulin resistance
P Shah, A Basu, R Rizza |
Current Diabetes Reports | 2003 |
Enhanced adrenergic mechanisms in glucose output from the kidney of diabetic rats
T Ikeda, K Iwata |
Metabolism | 2003 |
Use of a novel triple-tracer approach to assess postprandial glucose metabolism
R Basu, BD Camillo, G Toffolo, A Basu, P Shah, A Vella, R Rizza, C Cobelli |
American journal of physiology. Endocrinology and metabolism | 2003 |
Insulin Resistance and Risk of Chronic Kidney Disease in Nondiabetic US Adults
J Chen, P Muntner, LL Hamm, V Fonseca, V Batuman, PK Whelton, J He |
Journal of the American Society of Nephrology : JASN | 2003 |
Role of human liver, kidney, and skeletal muscle in postprandial glucose homeostasis
C Meyer, JM Dostou, SL Welle, JE Gerich |
American journal of physiology. Endocrinology and metabolism | 2002 |
The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phospatase expression
Jun Nakae, Tadahiro Kitamura, David L. Silver, Domenico Accili |
Journal of Clinical Investigation | 2001 |
Hepatic glucose uptake, gluconeogenesis and the regulation of glycogen synthesis
J Radziuk, S Pye |
Diabetes/Metabolism Research and Reviews | 2001 |
Type 2 diabetes impairs splanchnic uptake of glucose but does not alter intestinal glucose absorption during enteral glucose feeding: additional evidence for a defect in hepatic glucokinase activity
A Basu, R Basu, P Shah, A Vella, CM Johnson, M Jensen, KS Nair, WF Schwenk, RA Rizza |
Diabetes | 2001 |
Estudo da liberação renal de glicose em coelhos submetidos a hepatectomia total funcional e infusão de noradrenalina
AR FRANCHI-TEIXEIRA, GL JORGE, LS LEONARDI, MJ SAAD |
Arquivos de Gastroenterologia | 2001 |
Insulin-mediated increases in renal plasma flow are impaired in insulin-resistant normal subjects
JC Maaten, SJ Bakker, EH Serne, HJ Moshage, AJ Donker, RO Gans |
European Journal of Clinical Investigation | 2000 |
Regulation of splanchnic and renal substrate supply by insulin in humans
E Cersosimo, P Garlick, J Ferretti |
Metabolism | 2000 |
Role of the human kidney in glucose homeostasis:
C Meyer, JE Gerich |
Current Opinion in Endocrinology & Diabetes | 2000 |
Role of glutamine in human carbohydrate metabolism in kidney and other tissues
M Stumvoll, G Perriello, C Meyer, J Gerich |
Kidney International | 1999 |
The glucose-6 phosphatase gene is expressed in human and rat small intestine: Regulation of expression in fasted and diabetic rats
F Rajas, N Bruni, S Montano, C Zitoun, G Mithieux |
Gastroenterology | 1999 |
PHYSIOLOGY OF GLUCOSE COUNTERREGULATION TO HYPOGLYCEMIA
GB Bolli, CG Fanelli |
Endocrinology & Metabolism Clinics of North America | 1999 |
Increased glucose synthesis in renal tubule fragments from hyperthyroid rats
WP Pimenta, JA Veiga |
Canadian Journal of Physiology and Pharmacology | 1999 |
Increased dependence of glucose production on peripheral insulin in diabetic depancreatized dogs
A Giacca, R McCall, B Chan, ZQ Shi |
Metabolism | 1999 |
Important role of the kidney in human carbohydrate metabolism
M Stumvoll, C Meyer, A Mitrakou, JE Gerich |
Medical Hypotheses | 1999 |
Glucose-6-phosphatase mRNA levels in kidney isolated tubule suspensions are increased by dexamethasone and decreased by insulin
H Simonnet |
Metabolism | 1999 |
Substrate interactions in the short- and long-term regulation of renal glucose oxidation
MC Sugden, MJ Holness, E Donald, H Lall |
Metabolism | 1999 |
Effect of a selective rise in hepatic artery insulin on hepatic glucose production in the conscious dog
DK Sindelar, K Igawa, CA Chu, JH Balcom, DW Neal, AD Cherrington |
American journal of physiology. Endocrinology and metabolism | 1999 |
A critical evaluation of mass isotopomer distribution analysis of gluconeogenesis in vivo
SF Previs, GW Cline, GI Shulman |
American journal of physiology. Endocrinology and metabolism | 1999 |
Abnormal renal and hepatic glucose metabolism in type 2 diabetes mellitus
C Meyer, M Stumvoll, V Nadkarni, J Dostou, A Mitrakou, J Gerich |
Journal of Clinical Investigation | 1998 |
Die menschliche Niere als bedeutsamer Glucoseproduzent
M Stumvoll |
Medizinische Klinik | 1998 |
The Kidney's Role in Glucose Balance Following Partial Hepatectomy
CE Jones, K Koshibu, M DeCambre, JE Gerich, PQ Bessey, DA Krusch |
Journal of Surgical Research | 1998 |
Effects of glucagon on renal and hepatic glutamine gluconeogenesis in normal postabsorptive humans
M Stumvoll, C Meyer, M Kreider, G Perriello, J Gerich |
Metabolism | 1998 |
Human kidney and liver gluconeogenesis: evidence for organ substrate selectivity
M Stumvoll, C Meyer, G Perriello, M Kreider, S Welle, J Gerich |
American journal of physiology. Endocrinology and metabolism | 1998 |
Effects of β-adrenergic blockade on hepatic and renal glucose production during hypoglycemia in conscious dogs
E Cersosimo, IN Zaitseva, M Ajmal |
American journal of physiology. Endocrinology and metabolism | 1998 |
Insulin acutely suppresses glucose production by both peripheral and hepatic effects in normal dogs
RH McCall, SR Wiesenthal, ZQ Shi, K Polonsky, A Giacca |
American journal of physiology. Endocrinology and metabolism | 1998 |
Effects of physiological hyperinsulinemia on systemic, renal, and hepatic substrate metabolism
C Meyer, J Dostou, V Nadkarni, J Gerich |
American journal of physiology. Renal physiology | 1998 |
Regulation of hepatic glutamine metabolism during exercise in the dog
AE Halseth, N Rhéaume, AB Messina, EK Reed, MG Krishna, PJ Flakoll, DB Lacy, DH Wasserman |
American journal of physiology. Endocrinology and metabolism | 1998 |
Pharmacodynamic profile of a novel inhibitor of the hepatic glucose-6-phosphatase system
AW Herling, HJ Burger, D Schwab, H Hemmerle, P Below, G Schubert |
AJP Gastrointestinal and Liver Physiology | 1998 |
Critical Care Nephrology
C Ronco, R Bellomo |
1998 | |
Indirect effect of insulin to suppress endogenous glucose production is dominant, even with hyperglucagonemia
SD Mittelman, YY Fu, K Rebrin, G Steil, RN Bergman |
Journal of Clinical Investigation | 1997 |
Developmental Aspects of Transcription of Fructose- 1,6-Bisphosphatase in Newborn Dogs
B Feng, J Li, RM Kliegman |
Biochemical and Molecular Medicine | 1997 |
Techniques for assessing protein and glucose kinetics
PJ Garlick, E Cersosimo |
Baillière's Clinical Endocrinology and Metabolism | 1997 |
Glucose production and gluconeogenesis in postabsorptive and starved normal and streptozotocin-diabetic rats
O Peroni, V Large, F Diraison, M Beylot |
Metabolism | 1997 |
Human kidney free fatty acid and glucose uptake: evidence for a renal glucose-fatty acid cycle
C Meyer, V Nadkarni, M Stumvoll, J Gerich |
American journal of physiology. Endocrinology and metabolism | 1997 |
Interaction of equal increments in arterial and portal vein insulin on hepatic glucose production in the dog
DK Sindelar, CA Chu, DW Neal, AD Cherrington |
American journal of physiology. Endocrinology and metabolism | 1997 |
Inhibition of glycogenolysis enhances gluconeogenic precursor uptake by the liver of conscious dogs
M Shiota, PA Jackson, H Bischoff, M McCaleb, M Scott, M Monohan, DW Neal, AD Cherrington |
American journal of physiology. Endocrinology and metabolism | 1997 |
Role of the kidney in plasma glucose regulation during hyperglycemia
E Cersosimo, M Ajmal, RJ Naukam, PE Molina, NN Abumrad |
American journal of physiology. Endocrinology and metabolism | 1997 |
Effect of prior exercise on the partitioning of an intestinal glucose load between splanchnic bed and skeletal muscle
KS Hamilton, FK Gibbons, DP Bracy, DB Lacy, AD Cherrington, DH Wasserman |
Journal of Clinical Investigation | 1996 |
Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs
K Rebrin, GM Steil, SD Mittelman, RN Bergman |
Journal of Clinical Investigation | 1996 |
Substrate Metabolism in Humans: 1995 A.S.P.E.N. Research Workshop
S Klein, J Miles |
JPEN. Journal of parenteral and enteral nutrition | 1996 |
Acetaminophen glucuronidation accurately reflects gluconeogenesis in fasted dogs
WF Schwenk, JC Kahl |
American journal of physiology. Endocrinology and metabolism | 1996 |
Glutamine: a major gluconeogenic precursor and vehicle for interorgan carbon transport in man
N Nurjhan, A Bucci, G Perriello, M Stumvoll, G Dailey, DM Bier, I Toft, TG Jenssen, JE Gerich |
Journal of Clinical Investigation | 1995 |
Uptake and release of glucose by the human kidney. Postabsorptive rates and responses to epinephrine
M Stumvoll, U Chintalapudi, G Perriello, S Welle, O Gutierrez, J Gerich |
Journal of Clinical Investigation | 1995 |
Gluconeogenesis and Glucuronidation in Liver in Vivo and the Heterogeneity of Hepatocyte Function
K Ekberg, V Chandramouli, K Kumaran, WC Schumann, J Wahren, BR Landau |
The Journal of biological chemistry | 1995 |
Hepatic glycogen accurately reflected by acetaminophen glucuronide in dogs refed after fasting
KI Rother, WF Schwenk |
American journal of physiology. Endocrinology and metabolism | 1995 |
Gluconeogenesis
JH Exton |
Metabolism | 1972 |