Angiotensin II (Ang II) has been implicated in the development of progressive glomerulosclerosis, but the precise mechanism of this effect remains unclear. In an experimental model, we have shown previously that TGF-beta plays a key role in glomerulosclerosis by stimulating extracellular matrix protein synthesis, increasing matrix protein receptors, and altering protease/protease-inhibitor balance, thereby inhibiting matrix degradation. We hypothesized that Ang II contributes to glomerulosclerosis through induction of TGF-beta. Ang II treatment of rat mesangial cells in culture increased TGF-beta and matrix components biglycan, fibronectin, and collagen type I at both the mRNA and protein levels in a time- and dose-dependent manner. Saralasin, a competitive inhibitor of Ang II, prevented the stimulation. Ang II also promoted conversion of latent TGF-beta to the biologically active form. Coincubation of mesangial cells with Ang II and neutralizing antibody to TGF-beta blocked the Ang II-induced increases in matrix protein expression. Continuous in vivo administration of Ang II to normal rats for 7 d resulted in 70% increases in glomerular mRNA for both TGF-beta and collagen type I. These results indicate that Ang II induces mesangial cell synthesis of matrix proteins and show that these effects are mediated by Ang II induction of TGF-beta expression. This mechanism may well contribute to glomerulosclerosis in vivo.
S Kagami, W A Border, D E Miller, N A Noble
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Renal Fibrosis: Mechanisms and Therapies
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Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
Renal Fibrosis: Mechanisms and Therapies
BC Liu, HY Lan, LL Lv |
2019 | |
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Molecular and Cellular Biochemistry | 2016 |
Role of the Renin-Angiotensin-Aldosterone System beyond Blood Pressure Regulation: Molecular and Cellular Mechanisms Involved in End-Organ Damage during Arterial Hypertension
N Muñoz-Durango, C Fuentes, A Castillo, L González-Gómez, A Vecchiola, C Fardella, A Kalergis |
International journal of molecular sciences | 2016 |
Renal functional responses in diabetic nephropathy following chronic bilateral renal denervation
Y Yao, G Davis, JC Harrison, RJ Walker, IA Sammut |
Autonomic Neuroscience | 2016 |
Role of Angiotensin-(1-7) on Renal Hypertrophy in Streptozotocin-Induced Diabetes Mellitus
D Amato, AR Núñez-Ortiz, JC Benítez-Flores, D Segura-Cobos, P López-Sánchez, B Vázquez-Cruz |
Pharmacology & Pharmacy | 2016 |
Urinary Angiotensinogen Could Be a Prognostic Marker of the Renoprotection of Olmesartan in Metabolic Syndrome Patients
T Mizushige, H Kobori, H Hitomi, Y Nishijima, F Tomoda, S Morimoto, M Kohno, A Nishiyama |
International journal of molecular sciences | 2016 |
Sprue-Like Enteropathy Associated With Oxcarbazepine
PL González-Cordero, N Fernandez-Gonzalez, J Molina-Infante |
The American Journal of Gastroenterology | 2016 |
Endocrinology
C Napier, SH Pearce |
Endocrinology | 2016 |
Apelin-13 protects against myocardial infarction-induced myocardial fibrosis
X Zhang, W Hu, F Feng, J Xu, F Wu |
Molecular medicine reports | 2016 |
Involvement of the renin–angiotensin system in the development of nephrogenic systemic fibrosis-like lesions in the RenTag mouse model
S Sexton, R Tulowitzki, CA Jones, S Shah, G Hajduczok, KW Gross, M Panesar |
Clinical and Experimental Nephrology | 2015 |
Renin-angiotensin system blockade: Its contribution and controversy
A Miyajima, T Kosaka, E Kikuchi, M Oya |
International Journal of Urology | 2015 |
Histopathology of aortic complications in bicuspid aortic valve versus Marfan syndrome: relevance for therapy?
N Grewal, R Franken, BJ Mulder, MJ Goumans, JH Lindeman, MR Jongbloed, MC DeRuiter, RJ Klautz, AJ Bogers, RE Poelmann, AC Groot |
Heart and Vessels | 2015 |
Gastrointestinal Disorder Associated with Olmesartan Mimics Autoimmune Enteropathy
S Scialom, G Malamut, B Meresse, N Guegan, N Brousse, V Verkarre, C Derrieux, E Macintyre, P Seksik, G Savoye, G Cadiot, L Vuitton, L Marthey, F Carbonnel, N Cerf-Bensussan, C Cellier, AP Sampson |
PloS one | 2015 |
Urinary Angiotensinogen Could Be a Prognostic Marker of Renoprotective Effects of Alogliptin in Patients with Type 2 Diabetes
T Mizushige, H Kobori, Y Nishijima, Y Yano, K Sakata, M Hayakawa, A Nishiyama |
Journal of Diabetes Research | 2015 |
Diabetic Nephropathy Induced by Increased Ace Gene Dosage Is Associated with High Renal Levels of Angiotensin (1–7) and Bradykinin
N Bertoncello, RP Moreira, DY Arita, DS Aragão, IK Watanabe, PS Dantas, R Santos, R Mattar-Rosa, R Yokota, TS Cunha, DE Casarini |
Journal of Diabetes Research | 2015 |
Angiotensin II Levels in Gingival Tissues from Healthy Individuals, Patients with Nifedipine Induced Gingival Overgrowth and Non Responders on Nifedipine
A Balaji |
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH | 2015 |
Role of upstream stimulatory factor 2 in diabetic nephropathy
S Wang |
Frontiers in Biology | 2015 |
Clinical-Pathological Conference Series from the Medical University of Graz: Case No 156: 82-year-old woman with chronic diarrhea and weight loss of 20 kilograms
E Fabian, D Schiller, H Wenzl, C Lackner, J Donnerer, A Ziachehabi, R Silye, R Schöfl, GJ Krejs |
Wiener klinische Wochenschrift | 2015 |
Olmesartan-induced enteropathy: Letters to the Editor
N Heerasing, C Hair, S Wallace |
Internal Medicine Journal | 2015 |
Add-on Protective Effect of Pentoxifylline in Advanced Chronic Kidney Disease Treated with Renin-Angiotensin-Aldosterone System Blockade - A Nationwide Database Analysis
KL Kuo, SC Hung, JS Liu, YK Chang, CC Hsu, DC Tarng |
Scientific Reports | 2015 |
Follistatin-like 3 suppresses cell proliferation and fibronectin expression via p38MAPK pathway in rat mesangial cells cultured under high glucose
Xiaohong Wang, Liyin Shi, Zhe Han, Baoshan Liu |
International journal of clinical and experimental medicine | 2015 |
Pediatric Nephrology
ED Avner, WE Harmon, P Niaudet, N Yoshikawa, F Emma, S Goldstein |
Pediatric Nephrology | 2015 |
Extracellular matrix-induced Hic-5 expression in glomerular mesangial cells leads to a prosclerotic phenotype independent of TGF-β
N Hornigold, A Mooney |
The FASEB Journal | 2015 |
Identification of new cases of severe enteropathy has recently increased the spectrum of intestinal non-celiac villous atrophy
G Malamut, N Cerf-Bensussan, C Cellier |
Expert Review of Gastroenterology & Hepatology | 2015 |
Central role of IL-17/Th17 immune responses and the gut microbiota in the pathogenesis of intestinal fibrosis:
S Ray, CD Salvo, TT Pizarro |
Current Opinion in Gastroenterology | 2014 |
Cardiac valve cells and their microenvironment—insights from in vitro studies
H Wang, LA Leinwand, KS Anseth |
Nature Reviews Cardiology | 2014 |
Targeting reduction of proteinuria in glomerulonephritis: Maximizing the antifibrotic effect of valsartan by protecting podocytes
C Gu, G Zhou, NA Noble, WA Border, AK Cheung, Y Huang |
Journal of Renin-Angiotensin-Aldosterone System | 2014 |
Hypoxia and the extracellular matrix: drivers of tumour metastasis
DM Gilkes, GL Semenza, D Wirtz |
Nature Reviews Cancer | 2014 |
Ghrelin Protects against Renal Damages Induced by Angiotensin-II via an Antioxidative Stress Mechanism in Mice
K Fujimura, S Wakino, H Minakuchi, K Hasegawa, K Hosoya, M Komatsu, Y Kaneko, K Shinozuka, N Washida, T Kanda, H Tokuyama, K Hayashi, H Itoh |
PloS one | 2014 |
Signaling Pathways Involved in Renal Oxidative Injury: Role of the Vasoactive Peptides and the Renal Dopaminergic System
NL Mikusic, MC Kravetz, NM Kouyoumdzian, SL Penna, MI Rosón, BE Fernández, MR Choi |
Journal of Signal Transduction | 2014 |
Olmesartan attenuates tacrolimus-induced biochemical and ultrastructural changes in rat kidney tissue
NO Al-Harbi, F Imam, MM Al-Harbi, M Iqbal, A Nadeem, MM Sayed-Ahmed, AD Alabidy, AF Almukhallafi |
BioMed Research International | 2014 |
Drug-induced injury in the gastrointestinal tract
NC Panarelli |
Seminars in Diagnostic Pathology | 2014 |
The comparative effects of perindopril and catechin on mesangial matrix and podocytes in the streptozotocin induced diabetic rats
SP Ertürküner, M Başar, M Tunçdemir, İ Seçkin |
Pharmacological Reports | 2014 |
Renoprotective Effects of Direct Renin Inhibition in Glomerulonephritis:
K Miyata, R Satou, D Inui, A Katsurada, D Seth, A Davis, M Urushihara, H Kobori, KD Mitchell, LG Navar |
The American Journal of the Medical Sciences | 2014 |
Changes in urinary angiotensinogen posttreatment in pediatric IgA nephropathy patients
M Urushihara, T Nagai, Y Kinoshita, S Nishiyama, K Suga, N Ozaki, A Jamba, S Kondo, H Kobori, S Kagami |
Pediatric Nephrology | 2014 |
Angiotensin II: immunohistochemical study in Sardinian pterygium
P Demurtas, M Corrias, I Zucca, C Maxia, F Piras, P Sirigu, MT Perra |
European Journal of Histochemistry : EJH | 2014 |
Diabetes mellitus, a complex and heterogeneous disease, and the role of insulin resistance as a determinant of diabetic kidney disease
J Karalliedde, L Gnudi |
Nephrology Dialysis Transplantation | 2014 |
A new saikogenin from the roots of Bupleurum bicaule
N XU, YN SHI, X ZHONG, Y CAO, L WANG, TZ JIA |
Chinese Journal of Natural Medicines | 2014 |
Renal renin-angiotensin system —What supports and breaks the circle of life—
S Kagami |
Nihon Shoni Jinzobyo Gakkai Zasshi | 2014 |
Pharmacologic Targets and Peritoneal Membrane Remodeling
K Farhat, AW Stavenuiter, RH Beelen, PM Wee |
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis | 2014 |
Regulator of G protein signaling 2 (RGS2) deficiency accelerates the progression of kidney fibrosis
HS Jang, JI Kim, M Noh, MH Rhee, KM Park |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2014 |
Angiotensin II stimulates fibronectin protein synthesis via a G /arachidonic acid-dependent pathway
LD Alexander, Y Ding, S Alagarsamy, X Cui |
American journal of physiology. Renal physiology | 2014 |
Textbook of Organ Transplantation
J Stehlik, MS Kiernan, D Budge, MR Johnson |
Textbook of Organ Transplantation | 2014 |
The atypical chemokine receptor CCX-CKR regulates metastasis of mammary carcinoma via an effect on EMT
Y Harata-Lee, ME Turvey, JA Brazzatti, CE Gregor, MP Brown, MJ Smyth, I Comerford, SR McColl |
Immunology and Cell Biology | 2014 |
Ghrelin Protects against Renal Damages Induced by Angiotensin-II via an Antioxidative Stress Mechanism in Mice
K Fujimura, S Wakino, H Minakuchi, K Hasegawa, K Hosoya, M Komatsu, Y Kaneko, K Shinozuka, N Washida, T Kanda, H Tokuyama, K Hayashi, H Itoh, MC Vinci |
PloS one | 2014 |
Signaling Mechanism Underlying the Promotion of Keratinocyte Migration by Angiotensin II
H Sakai, K Matsuura, Y Tanaka, T Honda, T Nishida, M Inui |
Molecular pharmacology | 2014 |
Vascular Complications of Diabetes: Mechanisms of Injury and Protective Factors
C Rask-Madsen, GL King |
Cell Metabolism | 2013 |
Angiotensin II Type 1 Receptor Antagonist Attenuates Lacrimal Gland, Lung, and Liver Fibrosis in a Murine Model of Chronic Graft-Versus-Host Disease
S Yaguchi, Y Ogawa, S Shimmura, T Kawakita, S Hatou, S Satofuka, S Nakamura, T Imada, H Miyashita, S Yoshida, T Yaguchi, Y Ozawa, T Mori, S Okamoto, Y Kawakami, S Ishida, K Tsubota, PC Yang |
PloS one | 2013 |
Prevention of TGFβ induction attenuates angII-stimulated vascular biglycan and atherosclerosis in Ldlr-/- mice
T Tang, PG Wilson, JC Thompson, C Nelson, MH Yoder, LR Tannock |
Journal of lipid research | 2013 |
Beneficial Effects of the Activation of the Angiotensin-(1–7) Mas Receptor in a Murine Model of Adriamycin-Induced Nephropathy
KD Silveira, LC Barroso, AT Vieira, D Cisalpino, CX Lima, M Bader, RM Arantes, RA Santos, AC Simões-e-Silva, MM Teixeira, JC Dussaule |
PloS one | 2013 |
The role of urinary TGF-β1, TNF-α, IL-6 and microalbuminuria for monitoring therapy in posterior urethral valves
A Mandelia, M Bajpai, S Agarwala, AK Gupta, R Kumar, A Ali |
Pediatric Nephrology | 2013 |
Seldin and Giebisch's The Kidney
CJ Cooper, LD Dworkin, WL Henrich |
Seldin and Giebisch's The Kidney | 2013 |
Molecular mechanisms in the pathogenesis of diabetic nephropathy: An update
MK Arora, UK Singh |
Vascular Pharmacology | 2013 |
Cross talk between toll-like receptor-4 signaling and angiotensin-II in liver fibrosis development in the rat model of non-alcoholic steatohepatitis: Innate immunity in the liver fibrosis
Y Shirai, H Yoshiji, R Noguchi, K Kaji, Y Aihara, A Douhara, K Moriya, T Namisaki, H Kawaratani, H Fukui |
Journal of Gastroenterology and Hepatology | 2013 |
Plasma renin activity: An early marker of progressive renal disease in posterior urethral valves
M Bajpai, A Singh |
Journal of Indian Association of Pediatric Surgeons | 2013 |
Renoprotective effects of telmisartan after unilateral renal ablation in rats
T Matsuo, Y Miyata, Y Sagara, Y Higami, S Tobu, M Matsuo, M Noguchi, I Shimokawa, H Kanetake, H Sakai |
International journal of nephrology and renovascular disease | 2013 |
Therapeutic potential of targeting the renin angiotensin system in portal hypertension
CB Herath, JA Grace, PW Angus |
World journal of gastrointestinal pathophysiology | 2013 |
Losartan reverses permissive epigenetic changes in renal glomeruli of diabetic db/db mice
MA Reddy, P Sumanth, L Lanting, H Yuan, M Wang, D Mar, CE Alpers, K Bomsztyk, R Natarajan |
Kidney international. Supplement | 2013 |
The effect of RAAS blockade on the progression of diabetic nephropathy
SS Roscioni, HJ Heerspink, D Zeeuw |
Nature Reviews Nephrology | 2013 |
Time-course morphological and functional disorders of the kidney induced by long-term high-fat diet intake in female rats
CS Pinhal, A Lopes, DB Torres, SL Felisbino, JA Gontijo, PA Boer |
Nephrology Dialysis Transplantation | 2013 |
Prophylactic Add-on Antiplatelet Therapy in Chronic Kidney Disease With Type 2 Diabetes Mellitus: Comparison Between Clopidogrel and Low-dose Aspirin
A Dash, R Maiti, TK Bandakkanavar, A Bhaskar, J Prakash, BL Pandey |
International journal of preventive medicine | 2013 |
Prevention of TGFβ induction attenuates angII-stimulated vascular biglycan and atherosclerosis in Ldlr−/− mice1[S]
T Tang, PG Wilson, JC Thompson, C Nelson, MH Yoder, LR Tannock |
Journal of lipid research | 2013 |
Pathogenesis and Novel Treatment from the Mouse Model of Type 2 Diabetic Nephropathy
M Furukawa, T Gohda, M Tanimoto, Y Tomino |
The Scientific World JOURNAL | 2013 |
Prevention of TGFβ induction attenuates angII-stimulated vascular biglycan and atherosclerosis in Ldlr−/− mice
T Tang, PG Wilson, JC Thompson, C Nelson, MH Yoder, LR Tannock |
Journal of lipid research | 2013 |
Brazilian embauba ( Cecropia pachystachya ) extract reduces renal lesions in 5/6 nephrectomized rats
CC Maquiaveli, ER da Silva, HD Francescato, RS Costa, CG Silva, DE Casarini, FA Ronchi, TM Coimbra |
Journal of Renin-Angiotensin-Aldosterone System | 2013 |
The role of oxidative stress in renal injury induced in rats by losartan exposure during lactation
EC Marin, HD Francescato, RS Costa, CG da Silva, TM Coimbra |
Journal of Renin-Angiotensin-Aldosterone System | 2013 |
The effect of RAAS blockade on the progression of diabetic nephropathy
SS Roscioni, HJ Heerspink, D de Zeeuw |
Nature Reviews Nephrology | 2013 |
Transforming Growth Factor Beta, Bioenergetics and Mitochondria in Renal Disease
C Gabriella, D Ilse, B Erwin |
Seminars in Nephrology | 2012 |
Biological approaches to improve skeletal muscle healing after injury and disease
B Gharaibeh, Y Chun-Lansinger, T Hagen, SJ Ingham, V Wright, F Fu, J Huard |
Birth Defects Research Part C Embryo Today Reviews | 2012 |
Brenner and Rector's The Kidney
C Brugnara, KU Eckardt |
Brenner and Rector's The Kidney | 2012 |
Update on new aspects of the renin–angiotensin system in liver disease: clinical implications and new therapeutic options
JA Grace, CB Herath, KY Mak, LM Burrell, PW Angus |
Clinical Science | 2012 |
Severe Spruelike Enteropathy Associated With Olmesartan
A Rubio-Tapia, ML Herman, JF Ludvigsson, DG Kelly, TF Mangan, TT Wu, JA Murray |
Mayo Clinic Proceedings | 2012 |
Muscle
ML Martin, SL Belmonte, R Ram, FA Kamal, BC Blaxall |
Muscle | 2012 |
Garlic (Allium sativum) down-regulates the expression of angiotensin II AT1 receptor in adrenal and renal tissues of streptozotocin-induced diabetic rats
MH Mansour, K Al-Qattan, M Thomson, M Ali |
Inflammopharmacology | 2012 |
Captopril avoids hypertension, the increase in plasma angiotensin II but increases angiotensin 1-7 and angiotensin II-induced perfusion pressure in isolated kidney in SHR
P Castro-Moreno, JP Pardo, R Hernández-Muñoz, JJ López-Guerrero, LD Valle-Mondragón, G Pastelín-Hernández, M Ibarra-Barajas, R Villalobos-Molina |
Autonomic and Autacoid Pharmacology | 2012 |
Renoprotective Effects of Sildenafil in DOCA-Salt Hypertensive Rats
EH Bae, IJ Kim, SY Joo, EY Kim, CS Kim, JS Choi, SK Ma, SH Kim, JU Lee, SW Kim |
Kidney and Blood Pressure Research | 2012 |
Nop-7-associated 2 (NSA2), a candidate gene for diabetic nephropathy, is involved in the TGFβ1 pathway
R Shahni, A Czajka, BS Mankoo, AK Guvenel, A King, AN Malik |
The International Journal of Biochemistry & Cell Biology | 2012 |
Protective Effects of Quercetin on Streptozotocin-induced Diabetic Nephropathy in Rats: PROTECTIVE EFFECTS OF QUERCETIN ON DIABETIC NEPHROPATHY
H Hao, Q Lu, D Tang, Z Shao, X Yin, J Mou, Q Du |
Phytotherapy Research | 2012 |
Organ fibrosis inhibited by blocking transforming growth factor-β signaling via peroxisome proliferator-activated receptor γ agonists
YL Deng, XZ Xiong, NS Cheng |
Hepatobiliary & Pancreatic Diseases International | 2012 |
JAK-STAT and the renin-angiotensin system: The role of the JAK-STAT pathway in blood pressure and intrarenal renin-angiotensin system regulation
R Satou, RA Gonzalez-Villalobos |
JAK-STAT | 2012 |
Effects of Angiotensin Converting Enzyme Inhibitors on Liver Fibrosis in HIV and Hepatitis C Coinfection
LJ Reese, DS Tider, AC Stivala, DA Fishbein |
AIDS Research and Treatment | 2012 |
Role of the Transcription Factor Erythroblastosis Virus E26 Oncogen Homolog-1 (ETS-1) as Mediator of the Renal Proinflammatory and Profibrotic Effects of Angiotensin II
W Feng, P Chumley, P Hua, G Rezonzew, D Jaimes, MW Duckworth, D Xing, EA Jaimes |
Hypertension | 2012 |
The transcription factor ETS-1 regulates angiotensin II-stimulated fibronectin production in mesangial cells
P Hua, W Feng, G Rezonzew, P Chumley, EA Jaimes |
American journal of physiology. Renal physiology | 2012 |
Smoking in diabetic nephropathy: sparks in the fuel tank?
VA Chakkarwar |
World journal of diabetes | 2012 |
The periprosthetic capsule and connective tissue diseases: a piece in the puzzle of autoimmune/autoinflammatory syndrome induced by adjuvants
F Bassetto, C Scarpa, V Vindigni, A Doria |
Experimental biology and medicine (Maywood, N.J.) | 2012 |
Angiotensin receptor blockade attenuates cigarette smoke-induced lung injury and rescues lung architecture in a murine model
Megan Podowski, Carla Calvi, Shana Metzger, Kaori Misono, Hataya Poonyagariyagorn, Armando Lopez, Therese Ku, Thomas Lauer, Sharon McGrath-Morrow, Alan Berger, Christopher Cheadle, Rubin Tuder, Harry C. Dietz, III, Wayne Mitzner, Robert Wise, Enid Neptune |
Journal of Clinical Investigation | 2011 |
Activation of Src mediates PDGF-induced Smad1 phosphorylation and contributes to the progression of glomerulosclerosis in glomerulonephritis
A Mima, H Abe, K Nagai, H Arai, T Matsubara, M Araki, K Torikoshi, T Tominaga, N Iehara, A Fukatsu, T Kita, T Doi |
PloS one | 2011 |
Impaired Vascular Contractility and Aortic Wall Degeneration in Fibulin-4 Deficient Mice: Effect of Angiotensin II Type 1 (AT(1)) Receptor Blockade
E Moltzer, L Riet, SM Swagemakers, PM van Heijningen, M Vermeij, R Veghel, AM Bouhuizen, JH van Esch, S Lankhorst, NW Ramnath, MC de Waard, DJ Duncker, PJ van der Spek, EV Rouwet, AH Danser, J Essers |
PloS one | 2011 |
Addition of angiotensin II type 1 receptor blocker to CCR2 antagonist markedly attenuates crescentic glomerulonephritis
M Urushihara, N Ohashi, K Miyata, R Satou, OW Acres, H Kobori |
Hypertension | 2011 |
EGFR Signaling Promotes TGFβ-Dependent Renal Fibrosis
J Chen, JK Chen, K Nagai, D Plieth, M Tan, TC Lee, DW Threadgill, EG Neilson, RC Harris |
Journal of the American Society of Nephrology : JASN | 2011 |
TGF-β1 → SMAD/p53/USF2 → PAI-1 transcriptional axis in ureteral obstruction-induced renal fibrosis
R Samarakoon, JM Overstreet, SP Higgins, PJ Higgins |
Cell & Tissue Research | 2011 |
Comprehensive Physiology
R Terjung |
Comprehensive Physiology | 2011 |
Comprehensive Physiology
R Terjung |
Comprehensive Physiology | 2011 |
Comprehensive Physiology
R Terjung |
Comprehensive Physiology | 2011 |
Apelin protects against angiotensin II-induced cardiovascular fibrosis and decreases plasminogen activator inhibitor type-1 production
K Siddiquee, J Hampton, S Khan, D Zadory, L Gleaves, DE Vaughan, LH Smith |
Journal of Hypertension | 2011 |
Involvement of glomerular renin−angiotensin system (RAS) activation in the development and progression of glomerular injury
S Kagami |
Clinical and Experimental Nephrology | 2011 |
New Insights and Perspectives on Intrarenal Renin-Angiotensin System: Focus on Intracrine/Intracellular Angiotensin II*
JL Zhuo, XC Li |
Peptides | 2011 |
Renal (pro)renin receptor contributes to development of diabetic kidney disease through TGFβ1-CTGF signaling cascade
J Huang, LC Matavelli, HM Siragy |
Clinical and experimental pharmacology & physiology | 2011 |
Etiopathology of chronic tubular, glomerular and renovascular nephropathies: clinical implications
JM López-Novoa, AB Rodríguez-Peña, A Ortiz, C Martínez-Salgado, FJ Hernández |
Journal of Translational Medicine | 2011 |
Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases
JL Barnes, Y Gorin |
Kidney international. Supplement | 2011 |
The Ayurvedic medicine Salacia oblonga attenuates diabetic renal fibrosis in rats: suppression of angiotensin II/AT1 signaling
L He, Y Qi, X Rong, J Jiang, Q Yang, J Yamahara, M Murray, Y Li |
Evidence-based complementary and alternative medicine : eCAM | 2011 |
Angiotensin II type I receptor blockade suppresses glomerular renin-angiotensin system activation, oxidative stress, and progressive glomerular injury in rat anti- glomerular basement membrane glomerulonephritis
Y Kinoshita, S Kondo, M Urushihara, K Suga, S Matsuura, M Takamatsu, M Shimizu, A Nishiyama, H Kawachi, S Kagami |
Translational Research | 2011 |
The role of the renin–angiotensin system in thoracic aortic aneurysms: Clinical implications
E Moltzer, J Essers, JH van Esch, JW Roos-Hesselink, AH Danser |
Pharmacology & Therapeutics | 2011 |
Association between two genetic polymorphisms of the renin-angiotensin-aldosterone system and diabetic nephropathy: a meta-analysis
W Ding, F Wang, Q Fang, M Zhang, J Chen, Y Gu |
Molecular Biology Reports | 2011 |
Postnatal Renal Abnormalities in Rats Exposed to Losartan during Lactation
EC Marin, HD Francescato, CG da Silva, RS Costa, TM Coimbra |
Nephron Experimental Nephrology | 2011 |
Blood Pressure Lowering Effect of a Pea Protein Hydrolysate in Hypertensive Rats and Humans
H Li, N Prairie, CC Udenigwe, AP Adebiyi, PS Tappia, HM Aukema, PJ Jones, RE Aluko |
Journal of Agricultural and Food Chemistry | 2011 |
Furosemide induces mortality in a rat model of chronic heart failure
H Rokutan, C Suckow, S Haehling, S Strassburg, B Bockmeyer, W Doehner, C Waller, J Bauersachs, K Websky, B Hocher, SD Anker, J Springer |
International Journal of Cardiology | 2011 |
Renoprotective efficacy of valsartan in chronic non-diabetic proteinuric nephropathies with renin-angiotensin system gene polymorphisms
YJ Lee, HR Jang, SG Kim, DW Chae, JY Do, JE Lee, W Huh, DJ Kim, HY Oh, YG Kim |
Nephrology | 2011 |
Masa ventricular izquierda, función diastólica y marcadores de metabolismo del colágeno en la hipertensión arterial refractaria
CM Blanco, D Fatela-Cantillo, L Jiménez-Jiménez, RL Aguilar, R Moreno-Luna, AD Delgado, P Stiefel |
Medicina Clínica | 2011 |
Serum transforming growth factor-beta levels in patients with vitamin D deficiency
S Isik, U Ozuguz, YA Tutuncu, G Erden, D Berker, K Acar, Y Aydin, G Akbaba, N Helvaci, S Guler |
European Journal of Internal Medicine | 2011 |
Regulation of a novel angiotensin II precursor, proangiotensin-12, in the tissues by blockade of the rennin–angiotensin system
R Satou, H Kobori |
Hypertension Research | 2011 |
Irbesartan delays progression of nephropathy as measured by estimated glomerular filtration rate: post hoc analysis of the Irbesartan Diabetic Nephropathy Trial
M Evans, SC Bain, S Hogan, RW Bilous |
Nephrology Dialysis Transplantation | 2011 |
Angiotensinogen Expression Is Enhanced in the Progression of Glomerular Disease
M Urushihara, H Kobori |
International Journal of Clinical Medicine | 2011 |
A low-dose combination of valsartan and low molecular weight heparin better improved glomerular permeability than did high-dose monotherapy in rats with diabetic nephropathy
B Jiao, Y Zhang, Y Cheng, J Gao, Q Zhang |
Drug discoveries & therapeutics | 2011 |
Jak2-Independent Activation of Stat3 by Intracellular Angiotensin II in Human Mesangial Cells
R Singh |
Journal of Signal Transduction | 2011 |
Angiotensin II Sustains Brain Inflammation in Mice via Transforming Growth Factor Beta
Tobias Lanz, Zhaoqing Ding, Peggy Ho, Jian Luo, Ankur Agrawal, Hrishikesh Srinagesh, Robert Axtell, Hui Zhang, Michael Platten, Tony Wyss-Coray, Lawrence Steinman |
Journal of Clinical Investigation | 2010 |
Involvement of activated prorenin in the pathogenesis of slowly progressive nephropathy in the non-clipped kidney of two kidney, one-clip hypertension
M Ryuzaki, A Ichihara, Y Ohshima, M Sakoda, A Kurauchi-Mito, T Narita, K Kinouchi, K Murohashi-Bokuda, A Nishiyama, H Itoh |
Hypertension Research | 2010 |
Oxidative Stress in Diabetic Nephropathy
Kashihara N, Haruna Y, Kondeti VK, Kanwar YS |
Current medicinal chemistry | 2010 |
Asymmetric dimethylarginine (ADMA) induces chronic kidney disease through a mechanism involving collagen and TGF-β1 synthesis
F Mihout, N Shweke, N Bigé, C Jouanneau, JC Dussaule, P Ronco, C Chatziantoniou, JJ Boffa |
The Journal of Pathology | 2010 |
Tissue Renin-Angiotensin-Aldosterone Systems: Targets for Pharmacological Therapy
M Bader |
Annual Review of Pharmacology and Toxicology | 2010 |
New insights into the renoprotective actions of the renin inhibitor aliskiren in experimental renal disease
DL Feldman |
Hypertension Research | 2010 |
Vascular Basement Membrane Thickening in Diabetic Retinopathy
S Roy, J Ha, K Trudeau, E Beglova |
Current Eye Research | 2010 |
Common pathophysiological mechanisms of chronic kidney disease: Therapeutic perspectives
JM López-Novoa, C Martínez-Salgado, AB Rodríguez-Peña, FJ Hernández |
Pharmacology & Therapeutics | 2010 |
Stimulation of Reactive Oxygen Species and Collagen Synthesis by Angiotensin II in Cardiac Fibroblasts
PJ Lijnen, JF van Pelt, RH Fagard |
Cardiovascular Therapeutics | 2010 |
High glucose-induced apoptosis in bovine retinal pericytes is associated with transforming growth factor β and βIG-H3: βIG-H3 induces apoptosis in retinal pericytes by releasing Arg-Gly-Asp peptides
JH Han, SW Ha, IK Lee, BW Kim, JG Kim |
Clinical & Experimental Ophthalmology | 2010 |
Renin-angiotensin-aldosterone system blockade for cardiovascular diseases: current status
TK Ma, KK Kam, BP Yan, YY Lam |
British Journal of Pharmacology | 2010 |
Urinary angiotensinogen accurately reflects intrarenal Renin-Angiotensin system activity
M Urushihara, S Kondo, S Kagami, H Kobori |
American Journal of Nephrology | 2010 |
Enhanced angiotensin-converting enzyme 2 attenuates angiotensin II-induced collagen production via AT1 receptor–phosphoinositide 3-kinase–Akt pathway
L Bu, S Qu, X Gao, JJ Zou, W Tang, LL Sun, ZM Liu |
Endocrine | 2010 |
Fibronectin synthesis by high glucose level mediated proliferation of mouse embryonic stem cells: Involvement of ANG II and TGF-β1
YH Kim, JM Ryu, YJ Lee, HJ Han |
Journal of Cellular Physiology | 2010 |
Chymase inhibitor prevents the nonalcoholic steatohepatitis in hamsters fed a methionine- and choline-deficient diet
K Tashiro, S Takai, D Jin, H Yamamoto, K Komeda, M Hayashi, K Tanaka, N Tanigawa, M Miyazaki |
Hepatology Research | 2010 |
Angiotensin AT1 receptor activation mediates high glucose-induced epithelial-mesenchymal transition in renal proximal tubular cells
L Zhou, H Xue, P Yuan, J Ni, C Yu, Y Huang, LM Lu |
Clinical and Experimental Pharmacology and Physiology | 2010 |
Chymase inhibition attenuates tetrachloride-induced liver fibrosis in hamsters
K Komeda, S Takai, D Jin, K Tashiro, M Hayashi, N Tanigawa, M Miyazaki |
Hepatology Research | 2010 |
Tranilast attenuates the up-regulation of thioredoxin-interacting protein and oxidative stress in an experimental model of diabetic nephropathy
SM Tan, Y Zhang, AJ Cox, DJ Kelly, W Qi |
Nephrology Dialysis Transplantation | 2010 |
A review of mast cells and liver disease: What have we learned?
H Francis, CJ Meininger |
Digestive and Liver Disease | 2010 |
Differential expression of angiotensin II type 1 and type 2 receptors at the maternal-fetal interface: potential roles in early placental development
CL Tower, S Lui, NR Charlesworth, SD Smith, JD Aplin, RL Jones |
Reproduction | 2010 |
Angiotensin II mediates epithelial-to-mesenchymal transformation in tubular cells by ANG 1–7/MAS-1-dependent pathways
WC Burns, E Velkoska, R Dean, LM Burrell, MC Thomas |
American journal of physiology. Renal physiology | 2010 |
Glomerular type 1 (AT1) angiotensin receptors augment kidney injury and inflammation in autoimmune nephritis
Steven D. Crowley, Matthew Vasievich, Phillip Ruiz, Samantha K. Gould, Kelly K. Parsons, A. Kathy Pazmino, Benny J. Chen, Hyung-Suk Kim, Trinh T. Tran, David S. Pisetsky, Laura Barisoni, Minolfa C. Ptrieto-Carrasquero, Marie Jeansson, Mary H. Foster and Thomas M. Coffman |
Journal of Clinical Investigation | 2009 |
Vascular consequences of dietary salt intake
PW Sanders |
American journal of physiology. Renal physiology | 2009 |
Mechanism of VEGF expression by high glucose in proximal tubule epithelial cells
D Feliers, BS Kasinath |
Molecular and Cellular Endocrinology | 2009 |
Mechanisms of renal injury and progression of renal disease in congenital obstructive nephropathy
RL Chevalier, BA Thornhill, MS Forbes, SC Kiley |
Pediatric Nephrology | 2009 |
Protective Effect of Tanshinone IIA on the Early Stage of Experimental Diabetic Nephropathy
SK Kim, KH Jung, BC Lee |
Biological & Pharmaceutical Bulletin | 2009 |
The Rowett rat strain is resistant to renal fibrosis
G Kokeny, Z Nemeth, M Godo, P Hamar |
Nephrology Dialysis Transplantation | 2009 |
The Role of Na+-H+Exchanger Isoform 1 in Aldosterone-Induced Glomerulosclerosis in Vivo
M Zhang, J Chen, S Liu, L You, S Lin, Y Gu |
Renal Failure | 2009 |
Inhibition of intracellular Angiotensin II formation blocks high glucose effect on mesangial matrix
R Singh, D Choubey, J Chen, DJ Leehey |
Regulatory Peptides | 2009 |
Aldosterone-induced TGF-β1Expression is Regulated by Mitogen-Activated Protein Kinases and Activator Protein-1 in Mesangial Cells
JS Han, BS Choi, CW Yang, YS Kim |
Journal of Korean Medical Science | 2009 |
Losartan chemistry and its effects via AT1 mechanisms in the kidney
F Xu, C Mao, Y Liu, L Wu, Z Xu, L Zhang |
Current medicinal chemistry | 2009 |
The Relationship between Thymic Size and Vesicoureteral Reflux in Infants with Febrile Urinary Tract Infection
SK Jung, KH Park, HE Yim, KH Yoo, YS Hong, JW Lee |
Journal of the Korean Society of Pediatric Nephrology | 2009 |
Renoprotective effect of rosuvastatin in DOCA-salt hypertensive rats
EH Bae, IJ Kim, JW Park, SK Ma, JU Lee, SW Kim |
Nephrology Dialysis Transplantation | 2009 |
Angiotensin II activates connective tissue growth factor and induces extracellular matrix changes involving Smad/activation and p38 mitogen-activated protein kinase signalling pathways in human dermal fibroblasts
GY Zhang, X Li, CG Yi, H Pan, GD He, Q Yu, LF Jiang, WH Xu, ZJ Li, J Ding, DS Lin, WY Gao |
Experimental Dermatology | 2009 |
Combination Therapy with SMP-534 and an Angiotensin-Converting Enzyme Inhibitor Provides Additional Renoprotection in 5/6 Nephrectomized Rats
T Tsujimura, J Nagamine, E Sugaru, M Ono-Kishino, T Tokunaga, M Kitoh, R Nagata, T Nakagawa, M Taiji |
Biological & Pharmaceutical Bulletin | 2009 |
Rehmannia glutinosa ameliorates the progressive renal failure induced by 5/6 nephrectomy
BC Lee, JB Choi, HJ Cho, YS Kim |
Journal of Ethnopharmacology | 2009 |
Ocular Manifestations of Scleroderma
R Tailor, A Gupta, A Herrick, J Kwartz |
Survey of Ophthalmology | 2009 |
Intramuscular renin–angiotensin system is activated in human muscular dystrophy
G Sun, K Haginoya, H Dai, Y Chiba, M Uematsu, N Hino-Fukuyo, A Onuma, K Iinuma, S Tsuchiya |
Journal of the Neurological Sciences | 2009 |
Survival in type 2 diabetic patients in dialysis and the number of risk alleles in polymorphisms of the renin-angiotensin system genes
A Padromiquel, P Aliaramos, M Gonzalezalvarez, M Navarromoreno |
Clinical Biochemistry | 2009 |
Genetic Diseases of the Kidney
K Ichida, M Hosoyamada, T Hosoya, H Endou |
Genetic Diseases of the Kidney | 2009 |
Peptide Hormone Regulation of Angiogenesis
C Clapp, S Thebault, MC Jeziorski, GM de la Escalera |
Physiological reviews | 2009 |
Vascular consequences of dietary salt intake
PW Sanders |
American journal of physiology. Renal physiology | 2009 |
Roles of mitogen-activated protein kinases and angiotensin II in renal development
AP Balbi, HD Francescato, EC Marin, RS Costa, TM Coimbra |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] | 2009 |
JunD and HIF-1α mediate transcriptional activation of angiotensinogen by TGF-β1 in human lung fibroblasts
A Abdul-Hafez, R Shu, BD Uhal |
The FASEB Journal | 2009 |
Angiotensin-(1–7) activates growth-stimulatory pathways in human mesangial cells
J Zimpelmann, KD Burns |
American journal of physiology. Renal physiology | 2009 |
NOX enzymes and diabetic complications
T Kakehi, C Yabe-Nishimura |
Seminars in Immunopathology | 2008 |
Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: blockade of compensatory renin increase
Z Zhang, Y Zhang, G Ning, DK Deb, J Kong, YC Li |
Proceedings of the National Academy of Sciences | 2008 |
Expression of AT1 and AT2 angiotensin receptors in astrocytomas is associated with poor prognosis
O Arrieta, B Pineda-Olvera, P Guevara-Salazar, N Hernández-Pedro, D Morales-Espinosa, TL Cerón-Lizarraga, CH la Rosa, D Rembao, B Segura-Pacheco, J Sotelo |
British Journal of Cancer | 2008 |
Endogenous aldosterone contributes to acute angiotensin II-stimulated plasminogen activator inhibitor-1 and preproendothelin-1 expression in heart but not aorta
JM Luther, Z Wang, J Ma, N Makhanova, HS Kim, NJ Brown |
Endocrinology | 2008 |
Novel mechanisms of protein synthesis in diabetic nephropathy--role of mRNA translation
BS Kasinath, MM Mariappan, K Sataranatarajan, MJ Lee, GG Choudhury, D Feliers |
Reviews in Endocrine and Metabolic Disorders | 2008 |
Therapy in Nephrology & Hypertension
WL Whittier, JB Lewis, EJ Lewis |
Therapy in Nephrology & Hypertension | 2008 |
Fever Duration and Renal Scar in Pediatric Urinary Tract Infection
JI Jung, DH Lim, HE Yim, MS Park, KH Yoo, YS Hong, JW Lee |
Journal of the Korean Society of Pediatric Nephrology | 2008 |
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy
M Takamatsu, M Urushihara, S Kondo, M Shimizu, T Morioka, T Oite, H Kobori, S Kagami |
Pediatric Nephrology | 2008 |
VASOPRESSIN STIMULATES THE PRODUCTION OF EXTRACELLULAR MATRIX BY CULTURED RAT MESANGIAL CELLS
A Tahara, J Tsukada, Y Tomura, T Suzuki, T Yatsu, M Shibasaki |
Clinical and Experimental Pharmacology and Physiology | 2008 |
Effect of Angiotensin-Converting Enzyme Inhibition and Angiotensin II Type 1 Receptor Blockade on Streptozotocin-Induced Diabetic Nephropathy
S Sen, M Kanter, S Ustundag, C Aktas, H Dogutan, O Yalcin |
Renal Failure | 2008 |
Present and future drug treatments for chronic kidney diseases: evolving targets in renoprotection
N Perico, A Benigni, G Remuzzi |
Nature Reviews Drug Discovery | 2008 |
Low-Dose Losartan Therapy Reduces Proteinuria in Normotensive Patients with Immunoglobulin A Nephropathy
A SHIMIZU, T TAKEI, K UCHIDA, K TSUCHIYA, K NITTA |
Hypertension Research | 2008 |
Olmesartan Ameliorates Progressive Glomerular Injury in Subtotal Nephrectomized Rats through Suppression of Superoxide Production
S FUJIMOTO, M SATOH, H HORIKE, H HATTA, Y HARUNA, S KOBAYASHI, T NAMIKOSHI, S ARAKAWA, N TOMITA, N KASHIHARA |
Hypertension Research | 2008 |
Perindopril attenuates tubular hypoxia and inflammation in an experimental model of diabetic nephropathy in transgenicRen-2rats
KJ Wiggins, V Tiauw, Y Zhang, RE Gilbert, RG Langham, DJ Kelly |
Nephrology | 2008 |
Influence of Cytokine Gene Polymorphisms on IgA Nephropathy
C Bantis, P Heering, S Aker, N Kuhr, B Grabensee, K Ivens |
Renal Failure | 2008 |
Fibrosis in diabetes complications: pathogenic mechanisms and circulating and urinary markers
CR Ban, SM Twigg |
Vascular Health and Risk Management | 2008 |
Angiotensin II type 2 receptor antagonist reduces bleomycin-induced pulmonary fibrosis in mice
Y Waseda, M Yasui, Y Nishizawa, K Inuzuka, H Takato, Y Ichikawa, A Tagami, M Fujimura, S Nakao |
Respiratory Research | 2008 |
Stimulation of lymphocyte responses by angiotensin II promotes kidney injury in hypertension
SD Crowley, CW Frey, SK Gould, R Griffiths, P Ruiz, JL Burchette, DN Howell, N Makhanova, M Yan, HS Kim, PL Tharaux, TM Coffman |
American journal of physiology. Renal physiology | 2008 |
Angiotensin II- and glucose-stimulated extracellular matrix production: mediation by the insulin-like growth factor (IGF) axis in a murine mesangial cell line
LK Davis, BD Rodgers, KM Kelley |
Endocrine | 2008 |
The renin-angiotensin system and diabetes: an update
A Ribeiro-Oliveira, AI Nogueira, RM Pereira, WW Boas, RA Santos, AC Silva |
Vascular Health and Risk Management | 2008 |
Rosiglitazone Treatment Attenuates Expression of Inflammatory Hallmarks in the Remaining Kidney following Contralateral Nephrectomy
S Efrati, S Berman, A Chachashvili, N Cohen, Z Averbukh, J Weissgarten |
American Journal of Nephrology | 2008 |
MAPK and angiotensin II receptor in kidney of newborn rats from losartan-treated dams
AP Balbi, EC Marin, HD Francescato, RS Costa, TM Coimbra |
Pediatric Nephrology | 2008 |
Pathological Regression by Angiotensin II Type 1 Receptor Blockade in Patients with Mesangial Proliferative Glomerulonephritis
T OHTAKE, M OKA, K MAESATO, T MANO, R IKEE, H MORIYA, S KOBAYASHI |
Hypertension Research | 2008 |
Laminin and transforming growth factor beta-1 in children with vesicoureteric reflux
A Sabasiñska, W Zoch-Zwierz, A Wasilewska, T Porowski |
Pediatric Nephrology | 2008 |
Understanding the role of genetic polymorphisms in chronic kidney disease
K Luttropp, P Stenvinkel, JJ Carrero, R Pecoits-Filho, B Lindholm, L Nordfors |
Pediatric Nephrology | 2008 |
A positive effect of AII inhibitors on peritoneal membrane function in long-term PD patients
I Kolesnyk, M Noordzij, FW Dekker, EW Boeschoten, RT Krediet |
Nephrology Dialysis Transplantation | 2008 |
Angiotensin II activates the Smad pathway during epithelial mesenchymal transdifferentiation
G Carvajal, J Rodríguez-Vita, R Rodrigues-Díez, E Sánchez-López, M Rupérez, C Cartier, V Esteban, A Ortiz, J Egido, SA Mezzano, M Ruiz-Ortega |
Kidney International | 2008 |
Transforming growth factor- 1 is associated with kidney damage in patients with essential hypertension: renoprotective effect of ACE inhibitor and/or angiotensin II receptor blocker
S Zhu, Y Liu, L Wang, QH Meng |
Nephrology Dialysis Transplantation | 2008 |
All-transretinoic acid inhibits the increases in fibronectin and PAI-1 induced by TGF-β1 and Ang II in rat mesangial cells1
X LIU, L LÜ, B TAO, Y ZHU |
Acta Pharmacologica Sinica | 2008 |
ACE inhibitors and angiotensin II receptor antagonists in Crohn’s disease management
GE Hume, GL Radford-Smith |
Expert Review of Gastroenterology & Hepatology | 2008 |
Targeting the angiotensin pathway in idiopathic pulmonary fibrosis
SA Antoniu |
Expert Opinion on Therapeutic Targets | 2008 |
Effect of Pentoxifylline in Addition to Losartan on Proteinuria and GFR in CKD: A 12-Month Randomized Trial
SL Lin, YM Chen, WC Chiang, KD Wu, TJ Tsai |
American Journal of Kidney Diseases | 2008 |
Glomerular renin angiotensin system in streptozotocin diabetic and Zucker diabetic fatty rats
DJ Leehey, AK Singh, JP Bast, P Sethupathi, R Singh |
Translational Research | 2008 |
Renin–angiotensin system blockade in diabetic nephropathy
J Ahmad |
Diabetes and Metabolic Syndrome Clinical Research and Reviews | 2008 |
Renal Protective Effects of Leukotriene Receptor Blockers in an Experimental Model of Cyclosporine Nephrotoxicity
A Atakan, H Arikan, B Macunluoglu, S Tuglular, G Ulfer, F Cakalagaoglu, C Ozener, E Akoglu |
Transplantation Proceedings | 2008 |
Effects of Spironolactone in an Experimental Model of Chronic Cyclosporine Nephrotoxicity
B Macunluoglu, H Arikan, A Atakan, S Tuglular, G Ulfer, F Cakalagaoglu, C Ozener, E Akoglu |
Transplantation Proceedings | 2008 |
Local renal aldosterone production induces inflammation and matrix formation in kidneys of diabetic rats: Aldosterone and renal inflammation
HM Siragy, C Xue |
Experimental Physiology | 2008 |
Aldosterone and TGF- 1 synergistically increase PAI-1 and decrease matrix degradation in rat renal mesangial and fibroblast cells
W Huang, C Xu, KW Kahng, NA Noble, WA Border, Y Huang |
AJP Renal Physiology | 2008 |
Stimulation of lymphocyte responses by angiotensin II promotes kidney injury in hypertension
SD Crowley, CW Frey, SK Gould, R Griffiths, P Ruiz, JL Burchette, DN Howell, N Makhanova, M Yan, HS Kim, PL Tharaux, TM Coffman |
American journal of physiology. Renal physiology | 2008 |
Intracellular ANG II directly induces in vitro transcription of TGF-β1, MCP-1, and NHE-3 mRNAs in isolated rat renal cortical nuclei via activation of nuclear AT 1a receptors
XC Li, JL Zhuo |
American journal of physiology. Cell physiology | 2008 |
Angiotensin II increases the expression of the transcription factor ETS-1 in mesangial cells
DD Pearse, RX Tian, J Nigro, JB Iorgulescu, L Puzis, EA Jaimes |
American journal of physiology. Renal physiology | 2008 |
Systemic and local effects of angiotensin II blockade in experimental diabetic nephropathy
P Vieitez, O Gómez, ER Uceda, ME Vera, E Molina-Holgado |
Journal of Renin-Angiotensin-Aldosterone System | 2008 |
In-Stent Restenosis of the Renal Artery in a Single Kidney Patient: The Role of ACEI in the Therapeutic Choice
R Cianci, A Gigante, L Polidori, DD Donato, P Martina, B Barbano, R Renzulli, A Zaccaria, G Fuiano |
Angiology | 2008 |
Transforming Growth Factor-β in Cancer Therapy, Volume II
SB Jakowlew |
2008 | |
Effect of valsartan on the expression of angiotensin II receptors in the lung of chronic antigen exposure rats:
T WANG, K YIN, K LIU, G LU, Y LI, J CHEN |
Chinese Medical Journal | 2008 |
Diuretic Renography in Hydronephrosis: Delayed Tissue Tracer Transit Accompanies Both Functional Decline and Tissue Reorganization
A Schlotmann, JH Clorius, WK Rohrschneider, SN Clorius, F Amelung, K Becker |
Journal of Nuclear Medicine | 2008 |
MAPK and angiotensin II receptor in kidney of newborn rats from losartan-treated dams
AP Balbi, EC Marin, HD Francescato, RS Costa, TM Coimbra |
Pediatric Nephrology | 2008 |
Understanding the role of genetic polymorphisms in chronic kidney disease
K Luttropp, P Stenvinkel, JJ Carrero, R Pecoits-Filho, B Lindholm, L Nordfors |
Pediatric Nephrology | 2008 |
Laminin and transforming growth factor beta-1 in children with vesicoureteric reflux
A Sabasiñska, W Zoch-Zwierz, A Wasilewska, T Porowski |
Pediatric Nephrology | 2008 |
Crucial role of Rho-nuclear factor-kappaB axis in angiotensin II-induced renal injury
Y Ozawa, H Kobori |
American journal of physiology. Renal physiology | 2007 |
Pathogenesis and Classification of Proliferative Diabetic Vitreoretinopathy
P Kroll, EB Rodrigues, S Hoerle |
Ophthalmologica | 2007 |
Anti-inflammatory Renoprotective Effect of Clopidogrel and Irbesartan in Chronic Renal Injury
X Tu, X Chen, Y Xie, S Shi, J Wang, Y Chen, J Li |
Journal of the American Society of Nephrology : JASN | 2007 |
Expression of Angiotensin II Receptor Type 1 Is Reduced in Advanced Rat Liver Fibrosis
U Töx, I Scheller, N Kociok, MA Kern, D Klanac, SM Daudi, O Laue, P Schirmacher, T Goeser, S Schulte, HM Steffen |
Digestive Diseases and Sciences | 2007 |
Functional renin receptors in renal mesangial cells.
Huang Y, Border WA, Noble NA |
Current Hypertension Reports | 2007 |
Monocyte chemoattractant protein-1 has prosclerotic effects both in a mouse model of experimental diabetes and in vitro in human mesangial cells
S Giunti, GH Tesch, S Pinach, DJ Burt, ME Cooper, P Cavallo-Perin, G Camussi, G Gruden |
Diabetologia | 2007 |
Nitric oxide and vascular remodeling: Spotlight on the kidney
W Eberhardt, J Pfeilschifter |
Kidney International | 2007 |
Angiotensin II Receptor Blockade Ameliorates Mesangioproliferative Glomerulonephritis in Rats through Suppression of CTGF and PAI-1, Independently of the Coagulation System
N Liu, S Shimizu, T Ito-Ihara, K Takagi, T Kita, T Ono |
Nephron Experimental Nephrology | 2007 |
Functional renin receptors in renal mesangial cells
Y Huang, WA Border, NA Noble |
Current Hypertension Reports | 2007 |
Novel therapies blocking the renin–angiotensin–aldosterone system in the management of hypertension and related disorders
H Krum, RE Gilbert |
Journal of Hypertension | 2007 |
Angiotensin mediates renal fibrosis in the nephropathy of glycogen storage disease type Ia
WH Yiu, CJ Pan, RA Ruef, WT Peng, MF Starost, BC Mansfield, JY Chou |
Kidney International | 2007 |
New insights into the importance of aminopeptidase A in hypertension
S Mizutani, M Ishii, A Hattori, S Nomura, Y Numaguchi, M Tsujimoto, H Kobayshi, T Murohara, JW Wright |
Heart Failure Reviews | 2007 |
Enhanced TGF-b/Smad signaling in the early stage of diabetic nephropathy is independent of the AT1a receptor
Y Okazaki, Y Yamasaki, HA Uchida, K Okamoto, M Satoh, K Maruyama, Y Maeshima, H Sugiyama, T Sugaya, N Kashihara, H Makino |
Clinical and Experimental Nephrology | 2007 |
Resolving fibrosis in the diseased liver: Translating the scientific promise to the clinic
AK Muddu, IN Guha, AM Elsharkawy, DA Mann |
The International Journal of Biochemistry & Cell Biology | 2007 |
The Renin-Angiotensin System and Diabetic Nephropathy
SB Gurley, TM Coffman |
Seminars in Nephrology | 2007 |
Sphingosylphosphorylcholine stimulates expression of fibronectin through TGF-β1-Smad-dependent mechanism in human mesenchymal stem cells
HJ Moon, ES Jeon, YM Kim, MJ Lee, CK Oh, JH Kim |
The International Journal of Biochemistry & Cell Biology | 2007 |
Therapeutic potential of TGF-β inhibition in chronic renal failure
E Gagliardini, A Benigni |
Expert Opinion on Biological Therapy | 2007 |
TGF-β in Renal Injury and Disease
EP Böttinger |
Seminars in Nephrology | 2007 |
Effect of ACE inhibitors on angiotensin II in rat mesangial cells cultured in high glucose
R Singh, DJ Leehey |
Biochemical and Biophysical Research Communications | 2007 |
Mast cells and inflammatory kidney disease
U Blank, M Essig, L Scandiuzzi, M Benhamou, Y Kanamaru |
Immunological Reviews | 2007 |
Blockade of renin?angiotensin system in antifibrotic therapy
H Yoshiji, S Kuriyama, H Fukui |
Journal of Gastroenterology and Hepatology | 2007 |
Angiotensin receptor antagonist vs. angiotensin-converting enzyme inhibitor in Asian subjects with type 2 diabetes and albuminuria ? a randomized crossover study
SC Lim, AF Koh, SK Goh, CL Chua, BL Heng, T Subramaniam, CF Sum |
Diabetes, Obesity and Metabolism | 2007 |
Rho/Rho kinase is a key enzyme system involved in the angiotensin II signaling pathway of liver fibrosis and steatosis
K Kitamura, S Tada, N Nakamoto, K Toda, H Horikawa, S Kurita, S Tsunematsu, N Kumagai, H Ishii, H Saito, T Hibi |
Journal of Gastroenterology and Hepatology | 2007 |
The Effects of Angiotensin-Converting Enzyme Inhibitors on the Fibrous Envelope around Mammary Implants
OA Zimman, J Toblli, I Stella, M Ferder, L Ferder, F Inserra |
Plastic and Reconstructive Surgery | 2007 |
The up-regulation of angiotensin II receptor type 1 and connective tissue growth factor are involved in high-glucose-induced fibronectin production by cultured human dermal fibroblasts
N Yevdokimova, S Podpryatov |
Journal of Dermatological Science | 2007 |
Renoprotective role of the vitamin D receptor in diabetic nephropathy
Z Zhang, L Sun, Y Wang, G Ning, AW Minto, J Kong, RJ Quigg, YC Li |
Kidney International | 2007 |
Differential gene expression in response to transforming growth factor-β1 by fetal and postnatal dermal fibroblasts
KJ Rolfe, LM Irvine, AO Grobbelaar, C Linge |
Wound Repair and Regeneration | 2007 |
Losartan-hydrochlorothiazide association promotes lasting blood pressure normalization and completely arrests long-term renal injury in the 5/6 ablation model
CK Fujihara, DM Malheiros, R Zatz |
American journal of physiology. Renal physiology | 2007 |
The blockade of the renin-angiotensin system reverses tacrolimus related cardiovascular toxicity at the histopathological level
M Agirbasli, N Papila-Topal, B Ogutmen, H Deniz, F Cakalagaoglu, S Tuglular, E Akoglu |
Journal of Renin-Angiotensin-Aldosterone System | 2007 |
A Novel Phosphoinositide 3-Kinase-dependent Pathway for Angiotensin II/AT-1 Receptor-mediated Induction of Collagen Synthesis in MES-13 Mesangial Cells
N Yano, D Suzuki, M Endoh, TC Zhao, JF Padbury, YT Tseng |
The Journal of biological chemistry | 2007 |
Captopril Reduces Interstitial Renal Fibrosis and Preserves More Normal Renal Tubules in Neonatal Dogs with Partial Urethral Obstruction: A Preliminary Study
M Shirazi, A Noorafshan, MA Bahri, N Tanideh |
Urologia Internationalis | 2007 |
The Combination of ACE Inhibition plus Sympathetic Denervation Is Superior to ACE Inhibitor Monotherapy in the Rat Renal Ablation Model
P Hamar, G Kokeny, P Liptak, J Krtil, M Adamczak, K Amann, E Ritz, ML Gross |
Nephron Experimental Nephrology | 2007 |
Effects of Renin-Angiotensin System Blockade on Macrophage Infiltration in Patients with Hypertensive Nephrosclerosis
T IMAKIIRE, Y KIKUCHI, M YAMADA, T KUSHIYAMA, K HIGASHI, N HYODO, K YAMAMOTO, T ODA, S SUZUKI, S MIURA |
Hypertension Research | 2007 |
Impact of ACE Inhibitors and AII Receptor Blockers on Peritoneal Membrane Transport Characteristics in Long-Term Peritoneal Dialysis Patients
I Kolesnyk, FW Dekker, M Noordzij, S le Cessie, DG Struijk, RT Krediet |
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis | 2007 |
Loss of ACE2 leads to a late development of angiotensin II dependent glomerulosclerosis and compartmentalization of renal injury
Gavin Y. Oudit, Andrew M. Herzenberg, Zamaneh Kassiri, Mark C. Chappell, Heather Reich, Rama Khokha, Michael A. Crackower, Peter H. Backx, Josef M. Penninger, James W. Scholey |
The American Journal of Pathology | 2006 |
Plasminogen activator inhibitor-1 deficiency protects against aldosterone-induced glomerular injury
J Ma, A Weisberg, JP Griffin, DE Vaughan, AB Fogo, NJ Brown |
Kidney International | 2006 |
The link between Glut-1 and hypertension in diabetic nephropathy
L Gnudi, L Raij |
Current Hypertension Reports | 2006 |
ACE inhibition reduces glomerulosclerosis and regenerates glomerular tissue in a model of progressive renal disease
A Remuzzi, E Gagliardini, F Sangalli, M Bonomelli, M Piccinelli, A Benigni, G Remuzzi |
Kidney International | 2006 |
Interacting molecule of AT1 receptor, ATRAP, is colocalized with AT1 receptor in the mouse renal tubules
Y Tsurumi, K Tamura, Y Tanaka, Y Koide, M Sakai, M Yabana, Y Noda, T Hashimoto, M Kihara, N Hirawa, Y Toya, Y Kiuchi, M Iwai, M Horiuchi, S Umemura |
Kidney International | 2006 |
Combinational effect of genes for the renin–angiotensin system in conferring susceptibility to diabetic nephropathy
N Osawa, D Koya, S Araki, T Uzu, T Tsunoda, A Kashiwagi, Y Nakamura, S Maeda |
Journal of Human Genetics | 2006 |
Blockade of the renin–angiotensin–aldosterone system: a key therapeutic strategy to reduce renal and cardiovascular events in patients with diabetes
M Burnier, A Zanchi |
Journal of Hypertension | 2006 |
Renal injury due to renin–angiotensin–aldosterone system activation of the transforming growth factor-β pathway
G Wolf |
Kidney International | 2006 |
Renin increases mesangial cell transforming growth factor-β1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms
Y Huang, S Wongamorntham, J Kasting, D McQuillan, RT Owens, L Yu, NA Noble, W Border |
Kidney International | 2006 |
Preventive and therapeutic effects of angiotensin II type 1 receptor blocker on hepatic fibrosis induced by bile duct ligation in rats
M Ueki, M Koda, S Yamamoto, Y Matsunaga, Y Murawaki |
Journal of Gastroenterology | 2006 |
Renal artery stenosis and accelerated atherosclerosis: which comes first?
C Fava, P Minuz, P Patrignani, A Morganti |
Journal of Hypertension | 2006 |
Angiotensin II-stimulated collagen production in cardiac fibroblasts is mediated by reactive oxygen species
P Lijnen, I Papparella, V Petrov, A Semplicini, R Fagard |
Journal of Hypertension | 2006 |
Pharmacological management of renal fibrotic disease
J Gaedeke, HH Neumayer, H Peters |
Expert Opinion on Pharmacotherapy | 2006 |
Angiotensinogen and transforming growth factor beta1: novel genes in the pathogenesis of Crohn's disease
GE Hume, EV Fowler, D Lincoln, R Eri, D Templeton, TH Florin, JA Cavanaugh, GL Radford-Smith |
Journal of medical genetics | 2006 |
Young Scholars Award Lecture: Intratubular angiotensinogen in hypertension and kidney diseases
H Kobori, Y Ozawa, Y Suzaki, MC Prieto-Carrasquero, A Nishiyama, T Shoji, EP Cohen, LG Navar |
American Journal of Hypertension | 2006 |
Effect of salt intake on progression of chronic kidney disease
PW Sanders |
Current Opinion in Nephrology and Hypertension | 2006 |
Aldosterone promotes fibronectin production through a Smad2-dependent TGF-β1 pathway in mesangial cells
L Lai, J Chen, CM Hao, S Lin, Y Gu |
Biochemical and Biophysical Research Communications | 2006 |
Accurate Measurement and Clinical Significance of Urinary Transforming Growth Factor-Beta<sub>1</sub>
S Tsakas, DS Goumenos |
American Journal of Nephrology | 2006 |
The aetiology and pathogenesis of chronic allograft nephropathy
PJ Yates, ML Nicholson |
Transplant Immunology | 2006 |
Polymorphism of the renin–angiotensin–aldosterone system in patients with chronic allograft dysfunction
K Ayed, S Ayed-Jendoubi, TB Abdallah, R Bardi, Y Gorgi, I Sfar, B Dhrif, E Abderrahim, A Kheder |
Transplant Immunology | 2006 |
Cyclosporine reduction causes decreasing of angiotensin II and transforming growth factor-beta expression in chronic allograft nephropathy
MR Weir, JC Papadimitriou, CI Drachenberg, H Song, ST Bartlett, C Wei |
Journal of Cardiothoracic-Renal Research | 2006 |
Impact of Lotensin and Salviae on the Changes of TGF-Beta1 and Its Receptors in a Rat Model of Chronic Cyclosporine-Induced Nephropathy
B Peng, M Li, T Niu, S He |
Transplantation Proceedings | 2006 |
Inhibition of the Renin Angiotensin System Decreases Fibrogenic Cytokine Expression in Tacrolimus Nephrotoxicity in Rats
H Deniz, B Öğütmen, F Çakalağaoğlu, S Tuğlular, Ç Özener, E Akoğlu |
Transplantation Proceedings | 2006 |
Transforming Growth Factor- in Human Diabetic Nephropathy: Effects of ACE inhibition
RG Langham, DJ Kelly, RM Gow, Y Zhang, DJ Cordonnier, N Pinel, P Zaoui, RE Gilbert |
Diabetes care | 2006 |
Short-term nitric oxide inhibition induces progressive nephropathy after regression of initial renal injury
CK Fujihara, CR Sena, DM Malheiros, AL Mattar, R Zatz |
American journal of physiology. Renal physiology | 2006 |
Microalbuminúria: fator de risco cardiovascular e renal subestimado na prática clínica
MT Zanella |
Arquivos brasileiros de endocrinologia e metabologia | 2006 |
Angiotensin II formation in the kidney and nephrosclerosis in Ren-2 hypertensive rats
A Hartner, M Porst, B Klanke, N Cordasic, R Veelken, KF Hilgers |
Nephrology Dialysis Transplantation | 2006 |
The Diabetic Kidney
P Cortes, CE Mogensen |
2006 | |
Renovascular Hypertension: A Unique Cause of Unilateral Focal Segmental Glomerulosclerosis
B ALCHI, A SHIRASAKI, I NARITA, S NISHI, M UENO, T SAEKI, S MIYAMURA, F GEJYO |
Hypertension Research | 2006 |
Dual Blockade of the Renin-Angiotensin System in the Progression of Renal Disease: The Need for More Clinical Trials
G Fernandez-Juárez, V Barrio, SG de Vinuesa, M Goicoechea, M Praga, J Luño |
Journal of the American Society of Nephrology : JASN | 2006 |
Molecular Mechanisms and Therapeutic Strategies of Chronic Renal Injury: Role of Rho-Kinase in the Development of Renal Injury
K Hayashi, S Wakino, T Kanda, K Homma, N Sugano, T Saruta |
Journal of Pharmacological Sciences | 2006 |
Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney
CC Hou, W Wang, XR Huang, P Fu, TH Chen, D Sheikh-Hamad, HY Lan |
The American Journal of Pathology | 2005 |
Up-regulation of glomerular COX-2 by angiotensin II: Role of reactive oxygen species
EA Jaimes, RX Tian, D Pearse, L Raij |
Kidney International | 2005 |
Blockage of angiotensin II type I receptor decreases the synthesis of growth factors and induces apoptosis in C6 cultured cells and C6 rat glioma
O Arrieta, P Guevara, E Escobar, R García-Navarrete, B Pineda, J Sotelo |
British Journal of Cancer | 2005 |
Tissue-Specific Expression of Renin-Angiotensin System Components in IgA Nephropathy
C Miyake-Ogawa, M Miyazaki, K Abe, T Harada, Y Ozono, H Sakai, T Koji, S Kohno |
American Journal of Nephrology | 2005 |
An extremely high dose of losartan affords superior renoprotection in the remnant model
CK Fujihara, M Velho, DM Malheiros, R Zatz |
Kidney International | 2005 |
Imidapril, an Angiotensin-Converting Enzyme Inhibitor, Reduces Diabetes-Induced Renal Oxidative Damage in Mice
Y Naito, K Uchiyama, S Akagiri, W Aoi, G Hasegawa, N Nakamura, S Kokura, N Yoshida, H Ichikawa, S Toyokuni, T Yoshikawa |
Journal of Clinical Biochemistry and Nutrition | 2005 |
Renoprotective Effect of Early Inhibition of the Renin-Angiotensin System in Renal Transplant Recipients
D Montanaro, M Gropuzzo, P Tulissi, C Vallone, G Boscutti, R Mioni, A Risaliti, U Baccarani, GL Adani, M Sainz, F Bresadola, G Mioni |
Transplantation Proceedings | 2005 |
Agents in development for the treatment of diabetic nephropathy
K Fukami, ME Cooper, JM Forbes |
Expert Opinion on Investigational Drugs | 2005 |
Bone morphogenetic proteins in development and homeostasis of kidney
P Simic, S Vukicevic |
Cytokine & Growth Factor Reviews | 2005 |
Suppressive Effects of Iron on TGF-β<sub>1</sub> Production by Renal Proximal Tubular Epithelial Cells
T Horino, H Ito, T Yamaguchi, M Furihata, K Hashimoto |
Nephron Experimental Nephrology | 2005 |
Dual angiotensin-converting enzyme/neutral endopeptidase inhibition on cardiac and renal fibrosis and inflammation in DOCA-salt hypertensive rats
Q Pu, F Amiri, P Gannon, EL Schiffrin |
Journal of Hypertension | 2005 |
Angiotensin II receptor blocker inhibits p27Kip1 expression in glucose-stimulated podocytes and in diabetic glomeruli
ZG Xu, TH Yoo, DR Ryu, HC Park, SK Ha, DS Han, SG Adler, R Natarajan, SW Kang |
Kidney International | 2005 |
Levels of transforming growth factor beta 1 in south Indian type 2 diabetic subjects
V Viswanathan, C Snehalatha, MB Nair, R Kumutha, A Ramachandran |
Diabetes/Metabolism Research and Reviews | 2005 |
LOW RENIN-ANGIOTENSIN SYSTEM ACTIVITY GENE POLYMORPHISM AND DYSPLASIA ASSOCIATED WITH POSTERIOR URETHRAL VALVES
L Peruzzi, F Lombardo, A Amore, E Merlini, G Restagno, L Silvestro, T Papalia, R Coppo |
The Journal of Urology | 2005 |
Can Angiotensin Converting Enzyme Inhibitors Prevent Postoperative Adhesions?
N Bulbuller, YS Ilhan, C Kirkil, M Cetiner, Ö Gogebakan, N Ilhan |
Journal of Surgical Research | 2005 |
Advanced glycation end-product induces fractalkine gene upregulation in normal rat glomeruli
Y Kikuchi, T Imakiire, T Hyodo, T Kushiyama, K Higashi, N Hyodo, S Suzuki, S Miura |
Nephrology Dialysis Transplantation | 2005 |
Can Advanced Glycation End Product Inhibitors Modulate More than One Pathway to Enhance Renoprotection in Diabetes?
MT Coughlan, ME Cooper, JM Forbes |
Annals of the New York Academy of Sciences | 2005 |
The Renoprotective Potential of Pentoxifylline in Chronic Kidney Disease
SL Lin, WC Chiang, YM Chen, CF Lai, TJ Tsai, BS Hsieh |
Journal of the Chinese Medical Association | 2005 |
Effect of Valsartan versus Lisinopril on Peritoneal Sclerosis in Rats
S Duman, S ŞEn, C Duman, DG Oreopoulos |
The International Journal of Artificial Organs | 2005 |
POSTERIOR URETHRAL VALVES: PRELIMINARY OBSERVATIONS ON THE SIGNIFICANCE OF PLASMA RENIN ACTIVITY AS A PROGNOSTIC MARKER
M Bajpai, A Pratap, MA Tripathi, C Bal |
The Journal of Urology | 2005 |
Expression and Response to Angiotensin-Converting Enzyme Inhibition of Matrix Metalloproteinases 2 and 9 in Renal Glomerular Damage in Young Transgenic Rats with Renin-Dependent Hypertension
J Bolbrinker, S Markovic, M Wehland, WB Melenhorst, H van Goor, R Kreutz |
The Journal of pharmacology and experimental therapeutics | 2005 |
Angiotensin II Mediates High Glucose-Induced TGF-β1 and Fibronectin Upregulation in HPMC through Reactive Oxygen Species
H Noh, H Ha, MR Yu, YO Kim, JH Kim, HB Lee |
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis | 2005 |
Mesangial expression of angiotensin II receptor in IgA nephropathy and its regulation by polymeric IgA1
KN Lai, LY Chan, SC Tang, AW Tsang, FF Li, MF Lam, SL Lui, JC Leung |
Kidney International | 2004 |
Translational regulation of vascular endothelial growth factor expression in renal epithelial cells by angiotensin II
D Feliers, S Duraisamy, JL Barnes, G Ghosh-Choudhury, BS Kasinath |
American journal of physiology. Renal physiology | 2004 |
Angiotensin II in the lesional skin of systemic sclerosis patients contributes to tissue fibrosis via angiotensin II type 1 receptors
Y Kawaguchi, K Takagi, M Hara, C Fukasawa, T Sugiura, E Nishimagi, M Harigai, N Kamatani |
Arthritis & Rheumatism | 2004 |
Androgen Contributes to Gender-Related Cardiac Hypertrophy and Fibrosis in Mice Lacking the Gene Encoding Guanylyl Cyclase-A
Y Li, I Kishimoto, Y Saito, M Harada, K Kuwahara, T Izumi, I Hamanaka, N Takahashi, R Kawakami, K Tanimoto, Y Nakagawa, M Nakanishi, Y Adachi, DL Garbers, A Fukamizu, K Nakao |
Endocrinology | 2004 |
Microvascular complications of diabetes
Z He, GL King |
Endocrinology & Metabolism Clinics of North America | 2004 |
AGEs activate mesangial TGF-beta-Smad signaling via an angiotensin II type I receptor interaction
K Fukami, S Ueda, S Yamagishi, S Kato, Y Inagaki, M Takeuchi, Y Motomiya, R Bucala, S Iida, K Tamaki, T Imaizumi, ME Cooper, S Okuda |
Kidney International | 2004 |
From Hyperglycemia to Diabetic Kidney Disease: The Role of Metabolic, Hemodynamic, Intracellular Factors and Growth Factors/Cytokines
BF Schrijvers, AS Vriese, A Flyvbjerg |
Endocrine reviews | 2004 |
Diabetic nephropathy: Linking histology, cell biology, and genetics
S Adler |
Kidney International | 2004 |
Dual Effects of Endothelin-1 (1-31): Induction of Mesangial Cell Migration and Facilitation of Monocyte Recruitment through Monocyte Chemoattractant Protein-1 Production by Mesangial Cells
K ISHIZAWA, M YOSHIZUMI, K TSUCHIYA, H HOUCHI, K MINAKUCHI, Y IZAWA, Y KANEMATSU, S KAGAMI, M HIROSE, T TAMAKI |
Hypertension Research | 2004 |
The role of bradykinin in the antifibrotic actions of perindoprilat on human mesangial cells
IZ Pawluczyk, SR Patel, KP Harris |
Kidney International | 2004 |
Combining TGF-beta inhibition and angiotensin II blockade results in enhanced antifibrotic effect
L Yu, WA Border, I Anderson, M McCourt, Y Huang, NA Noble |
Kidney International | 2004 |
Reduction of bleomycin induced lung fibrosis by candesartan cilexetil, an angiotensin II type 1 receptor antagonist
M Otsuka, H Takahashi, M Shiratori, H Chiba, S Abe |
Thorax | 2004 |
An ACE inhibitor reduces Th2 cytokines and TGF-beta1 and TGF-beta2 isoforms in murine lupus nephritis
DA de Albuquerque, V Saxena, DE Adams, GP Boivin, HI Brunner, DP Witte, RR Singh |
Kidney International | 2004 |
Combination Therapy with Angiotensin-Converting Enzyme Inhibitor and Oral Adsorbent of Uremic Toxins Can Delay the Appearance of Glomerular Sclerosis and Interstitial Fibrosis in Established Renal Failure
K Okada, E Okawa, H Shibahara, T Maruyama, N Maruyama, K Matsumoto, S Takahashi |
Kidney and Blood Pressure Research | 2004 |
Role of nitric oxide in diabetic nephropathy
SS Prabhakar |
Seminars in Nephrology | 2004 |
Effect of Angiotensin II on Glomerular Structure in Streptozotocin-Induced Diabetic Rats
SB Nicholas, M Mauer, JM Basgen, E Aguiniga, Y Chon |
American Journal of Nephrology | 2004 |
PREVENTION OF RENAL FIBROSIS BY SPIRONOLACTONE IN MICE WITH COMPLETE UNILATERAL URETERAL OBSTRUCTION
H Trachtman, AC Weiser, E Valderrama, M Morgado, LS Palmer |
The Journal of Urology | 2004 |
Review Article. Pentoxifylline: A potential therapy for chronic kidney disease
SL Lin, YM Chen, WC Chiang, TJ Tsai, WY Chen |
Nephrology | 2004 |
Transforming growth factor beta1 at clinical onset of Type 1 diabetes mellitus. A pilot study
L Flores, S Naf, R Hernaez, I Conget, R Gomis, E Esmatjes |
Diabetic Medicine | 2004 |
Hypertension, transforming growth factor-β, angiotensin II and kidney disease
A Bobik |
Journal of Hypertension | 2004 |
Imidapril improves l-NAME-exacerbated nephrosclerosis with TGF-β1 inhibition in spontaneously hypertensive rats
H Ono, M Saitoh, Y Ono, T Ishimitu, H Matsuoka |
Journal of Hypertension | 2004 |
Role of endothelin ETB receptor in partial ablation-induced chronic renal failure in rats
Y Okada, M Nakata, H Izumoto, M Takasu, N Tazawa, M Takaoka, CE Gariepy, M Yanagisawa, Y Matsumura |
European Journal of Pharmacology | 2004 |
Antifibrotic effect of the Chinese herbs, Astragalus mongholicus and Angelica sinensis, in a rat model of chronic puromycin aminonucleoside nephrosis
H Wang, J Li, L Yu, Y Zhao, W Ding |
Life Sciences | 2004 |
.BETA.1-integrins and glomerular injury
S Kagami, S Kondo |
The Journal of Medical Investigation | 2004 |
Renal synthesis of urokinase type-plasminogen activator, its receptor, and plasminogen activator inhibitor-1 in diabetic nephropathy in rats: Modulation by angiotensin-converting–enzyme inhibitor
M Kenichi, M Masanobu, K Takehiko, T Shoko, F Akira, A Katsushige, H Takashi, O Yoshiyuki, K Shigeru |
Journal of Laboratory and Clinical Medicine | 2004 |
Renal allograft protection with early angiotensin-converting enzyme inhibitors administration
D Montanaro, M Gropuzzo, P Tulissi, G Boscutti, R Mioni, A Risaliti, U Baccarani, GL Adani, M Sainz, F Bresadola, G Mioni |
Transplantation Proceedings | 2004 |
Effect of aldosterone on renal transforming growth factor-
I Juknevicius |
AJP Renal Physiology | 2004 |
Angiotensin II type 1 receptor interaction is an important regulator for the development of pancreatic fibrosis in mice
Y Nagashio, H Asaumi, S Watanabe, Y Nomiyama, M Taguchi, M Tashiro, T Sugaya, M Otsuki |
AJP Gastrointestinal and Liver Physiology | 2004 |
High glucose concentration stimulates intracellular renin activity and angiotensin II generation in rat mesangial cells
DB Vidotti, DE Casarini, PC Cristovam, CA Leite, N Schor, MA Boim |
American journal of physiology. Renal physiology | 2004 |
Ultrastructural alterations in capillaries of the diabetic hypertensive rat retina: protective effects of ACE inhibition
AA Dosso, E Rungger-Brändle, PM Leuenberger |
Diabetologia | 2004 |
Angiotensin II induces thrombospondin-1 production in human mesangial cells via p38 MAPK and JNK: a mechanism for activation of latent TGF-β 1
T Naito, T Masaki, DJ Nikolic-Paterson, C Tanji, N Yorioka, N Kohno |
American journal of physiology. Renal physiology | 2004 |
Postnatal renal development of rats from mothers that received increased sodium intake
AP Balbi, RS Costa, TM Coimbra |
Pediatric Nephrology | 2004 |
Hexosamines and TGF-β 1 use similar signaling pathways to mediate matrix protein synthesis in mesangial cells
LP Singh, K Green, M Alexander, S Bassly, ED Crook |
American journal of physiology. Renal physiology | 2004 |
Molecular and clinical response to angiotensin�II receptor antagonist in kidney transplant patients with chronic allograft nephropathy
VR Mas, T Alvarellos, DG Maluf, A Ferreira-Gonzalez, L Oliveros, RA Maldonado, G Boccardo |
Transplant International | 2004 |
Urinary transforming growth factor-β1 in various types of nephropathy
PD Muro, R Faedda, P Fresu, A Masala, A Cigni, G Concas, MG Mela, A Satta, A Carcassi, GM Sanna, GM Cherchi |
Pharmacological research : the official journal of the Italian Pharmacological Society | 2004 |
Beneficial Effect of Angiotensin-Blocking Agents on Graft Fibrosis in Hepatitis C Recurrence after Liver Transplantation:
A Rimola, MC Londoo, G Guevara, M Bruguera, M Navasa, X Forns, M Garca-Retortillo, JC Garca-Valdecasas, J Rodes |
Transplantation | 2004 |
Angiotensin Vol. II
T Unger, BA Schölkens |
2004 | |
Bone Morphogenetic Proteins: Regeneration of Bone and Beyond
S Vukicevic, KT Sampath |
2004 | |
Combination Therapy with an Angiotensin-Converting Enzyme Inhibitor and an Angiotensin II Receptor Blocker Synergistically Suppresses Chronic Pancreatitis in Rats
T Yamada, A Kuno, K Ogawa, M Tang, K Masuda, S Nakamura, T Ando, T Okamoto, H Ohara, T Nomura, T Joh, T Shirai, M Itoh |
The Journal of pharmacology and experimental therapeutics | 2004 |
The Renin–Angiotensin System and Peritoneal Dialysis
S Duman, A Breborowicz |
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis | 2004 |
Dietary salt intake modulates progression of antithymocyte serum nephritis through alteration of glomerular angiotensin II receptor expression
H Suzuki, T Yamamoto, N Ikegaya, A Hishida |
American journal of physiology. Renal physiology | 2003 |
Extracellular Matrix Metabolism in Diabetic Nephropathy
RM Mason, NA Wahab |
Journal of the American Society of Nephrology : JASN | 2003 |
International Textbook of Diabetes Mellitus
RA DeFronzo, L Mandarino, E Ferrannini |
International Textbook of Diabetes Mellitus | 2003 |
Angiotensin II and the glomerulus: Focus on diabetic kidney disease
JW Scholey |
Current Hypertension Reports | 2003 |
Long-term treatment with ramipril attenuates renal osteopontin expression in diabetic rats
C Li, CW Yang, CW Park, HJ Ahn, WY Kim, KH Yoon, SH Suh, SW Lim, JH Cha, YS Kim, J Kim, YS Chang, BK Bang |
Kidney International | 2003 |
Abnormal angiogenesis in diabetes mellitus
A Martin, MR Komada, DC Sane |
Medicinal Research Reviews | 2003 |
Hypertension Accelerates Diabetic Nephropathy in Wistar Fatty Rats, a Model of Type 2 Diabetes Mellitus, via Mitogen-Activated Protein Kinase Cascades and Transforming Growth Factor-.BETA.1
G IMAI, T SATOH, T KUMAI, M MURAO, H TSUCHIDA, Y SHIMA, G OGIMOTO, T FUJINO, S KOBAYASHI, K KIMURA |
Hypertension Research | 2003 |
Effects of Exercise Training on Glomerular Structure in Fructose-Fed Spontaneously Hypertensive Rats
K YOSHIDA, T KAWAMURA, HL XU, L JI, N MORI, M KOHZUKI |
Hypertension Research | 2003 |
A novel potential therapy for diabetic nephropathy and vascular complications: protein kinase C β inhibition
KR Tuttle, PW Anderson |
American Journal of Kidney Diseases | 2003 |
Effect of fasudil on Rho-kinase and nephropathy in subtotally nephrectomized spontaneously hypertensive rats
T Kanda, S Wakino, K Hayashi, K Homma, Y Ozawa, T Saruta |
Kidney International | 2003 |
Changes of angiotensin-converting enzyme activity in the pancreas of chronic hypoxia and acute pancreatitis
SP Ip, PC Kwan, CH Williams, S Pang, NM Hooper, PS Leung |
The International Journal of Biochemistry & Cell Biology | 2003 |
An angiotensin II type 1 receptor antagonist, olmesartan medoxomil, improves experimental liver fibrosis by suppression of proliferation and collagen synthesis in activated hepatic stellate cells
N Kurikawa, M Suga, S Kuroda, K Yamada, H Ishikawa |
British Journal of Pharmacology | 2003 |
Gene therapy and tissue engineering for sports medicine
J Huard, Y Li, H Peng, FH Fu |
The Journal of Gene Medicine | 2003 |
TGF-beta isoforms in renal fibrogenesis
L Yu, WA Border, Y Huang, NA Noble |
Kidney International | 2003 |
Effect of enalapril and losartan on the events that precede diabetic nephropathy in rats
RA Volpini, CG da Silva, RS Costa, TM Coimbra |
Diabetes/Metabolism Research and Reviews | 2003 |
The intrarenal renin–angiotensin system and diabetic nephropathy
RM Carey, HM Siragy |
Trends in Endocrinology & Metabolism | 2003 |
Induction of MIF synthesis and secretion by tubular epithelial cells: A novel action of angiotensin II
EK Rice, GH Tesch, Z Cao, ME Cooper, CN Metz, R Bucala, RC Atkins, DJ Nikolic-Paterson |
Kidney International | 2003 |
Diabetic nephropathy and transforming growth factor-β: transforming our view of glomerulosclerosis and fibrosis build-up
S Chen, B Jim, FN Ziyadeh |
Seminars in Nephrology | 2003 |
Cardiac allograft vasculopathy: current concepts and treatment
J Waller, NR Brook, ML Nicholson |
Transplant International | 2003 |
Evaluation of p53, bcl-2, and Interleukin-15 Levels in Gingival Crevicular Fluid of Cyclosporin A-Treated Patients
E Buduneli, F Genel, G Atilla, N Kütükçüçler |
Journal of Periodontology | 2003 |
Regulation of Glucose Transporter (GLUT1) Gene Expression by Angiotensin II in Mesangial Cells: Involvement of HB-EGF and EGF Receptor Transactivation
A NOSE, Y MORI, Y UCHIYAMA-TANAKA, N KISHIMOTO, K MARUYAMA, H MATSUBARA, T IWASAKA |
Hypertension Research | 2003 |
Role of protein kinase C-angiotensin II pathway for extracellular matrix production in cultured human mesangial cells exposed to high glucose levels
K Ikehara, H Tada, K Kuboki, T Inokuchi |
Diabetes Research and Clinical Practice | 2003 |
Comparative effects of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers on blood pressure and the kidney
JM Thurman, RW Schrier |
The American Journal of Medicine | 2003 |
Progression of chronic renal disease
S Klahr, J Morrissey |
American Journal of Kidney Diseases | 2003 |
Angiotensin-converting enzyme inhibitor attenuates pancreatic inflammation and fibrosis in male Wistar Bonn/Kobori rats
A Kuno, T Yamada, K Masuda, K Ogawa, M Sogawa, S Nakamura, T Nakazawa, H Ohara, T Nomura, T Joh, T Shirai, M Itoh |
Gastroenterology | 2003 |
Amino acids induce indicators of response to injury in glomerular mesangial cells
RL Meek, SK Cooney, SD Flynn, RF Chouinard, MH Poczatek, JE Murphy-Ullrich, KR Tuttle |
American journal of physiology. Renal physiology | 2003 |
Smad3 and PKCδ mediate TGF-β 1 -induced collagen I expression in human mesangial cells
CE Runyan, HW Schnaper, AC Poncelet |
American journal of physiology. Renal physiology | 2003 |
Angiotensin II mediates LDL-induced superoxide generation in mesangial cells
SY Park, CY Song, BC Kim, HK Hong, HS Lee |
American journal of physiology. Renal physiology | 2003 |
TA Repeat Variation, Npr1 Expression, and Blood Pressure: Impact of the Ace Locus
J Tremblay, DH Hum, R Sanchez, P Dumas, M Pravenec, D Křenova, V Křen, J Kuneš, Z Pausova, F Gossard, P Hamet |
Hypertension | 2003 |
Angiotensin-Converting Enzyme Inhibition but not Angiotensin II Receptor Blockade Regulates Matrix Metalloproteinase Activity in Patients with Glomerulonephritis
N Lods, P Ferrari, FJ Frey, A Kappeler, C Berthier, B Vogt, HP Marti |
Journal of the American Society of Nephrology : JASN | 2003 |
Angiotensin II AT1 Receptor Antagonists. Clinical Implications of Active Metabolites
B Schmidt, B Schieffer |
Journal of Medicinal Chemistry | 2003 |
Polymeric IgA1 from Patients with IgA Nephropathy Upregulates Transforming Growth Factor-β Synthesis and Signal Transduction in Human Mesangial Cells via the Renin-Angiotensin System
KN Lai, SC Tang, JY Guh, TD Chuang, MF Lam, LY Chan, AW Tsang, JC Leung |
Journal of the American Society of Nephrology : JASN | 2003 |
Transforming growth factor-beta1 is up-regulated by podocytes in response to excess intraglomerular passage of proteins: a central pathway in progressive glomerulosclerosis
M Abbate, C Zoja, M Morigi, D Rottoli, S Angioletti, S Tomasoni, C Zanchi, L Longaretti, R Donadelli, G Remuzzi |
The American Journal of Pathology | 2002 |
Role of Hypolipidemic Drug Clofibrate in Altering Iron Regulatory Proteins IRP1 and IRP2 Activities and Hepatic Iron Metabolism in Rats Fed a Low-Iron Diet
HL Huang, NS Shaw |
Toxicology and Applied Pharmacology | 2002 |
The Renin-Angiotensin-Aldosterone System and Fibrinolysis in Progressive Renal Disease
NJ Brown, DE Vaughan, AB Fogo |
Seminars in Nephrology | 2002 |
Response of mesangial cells to low-density lipoprotein and angiotensin II in diabetic (OLETF) rats
M Okada, T Takemura, H Yanagida, K Yoshioka |
Kidney International | 2002 |
Additive antiproteinuric effect of combined ACE inhibition and angiotensin II receptor blockade
P Ferrari, HP Marti, M Pfister, FJ Frey |
Journal of Hypertension | 2002 |
Chronic Angiotensin-Converting Enzyme Inhibition and Angiotensin II Antagonism in Rats With Chronic Renal Failure
K Yoshida, HL Xu, T Kawamura, L Ji, M Kohzuki |
Journal of Cardiovascular Pharmacology | 2002 |
The role of angiotensin II antagonism in type 2 diabetes mellitus: a review of renoprotection studies
MT Zanella, AB Ribeiro |
Clinical Therapeutics | 2002 |
Class benefits of AT1antagonists in Type 2 diabetes with nephropathy
SA Doggrell |
Expert Opinion on Pharmacotherapy | 2002 |
Angiotensin converting enzyme inhibitors and angiotensin II receptor blockers: Evidence for and against the combination in the treatment of hypertension and proteinuria
NH Andersen, CE Mogensen |
Current Hypertension Reports | 2002 |
Angiotensin II and progressive renal insufficiency
J Gaedeke, NA Noble, WA Border |
Current Hypertension Reports | 2002 |
THE ACE INHIBITOR, QUINAPRIL, AMELIORATES PERITONEAL FIBROSIS IN AN ENCAPSULATING PERITONEAL SCLEROSIS MODEL IN MICE
T Sawada, Y Ishii, T Tojimbara, I Nakajima, S Fuchinoue, S Teraoka |
Pharmacological Research | 2002 |
Renal Protective Effect of Candesartan Cilexetil in Spontaneously Hypercholesterolemic Rats
T Matsuo, E Ishikawa, M Ohta, Y Shibouta, Y Ishimura, Y Imura, Y Sugiyama |
The Japanese Journal of Pharmacology | 2002 |
Perindopril: possible use in cancer therapy
H Yoshiji, S Kuriyama, H Fukui |
Anti-Cancer Drugs | 2002 |
Effects of Angiotensin II Subtype 1 Receptor Blockade by Losartan on Tubulointerstitial Lesions Caused by Hyperoxaluria
JE Toblli, L Ferder, I Stella, EM de Cavanagh, M Angerosa, F Inserra |
The Journal of Urology | 2002 |
Increased transforming growth factor-β1 and tubulointerstitial fibrosis in rats with congenital hydronephrosis
Y Zhou, G Takahashi, T Shinagawa, T Okuhara, K Yonamine, Y Aida, M Tadokoro |
International Journal of Urology | 2002 |
Effects of amino acids and glucose on mesangial cell aminopeptidase a and angiotensin receptors
RF Chouinard, RL Meek, SK Cooney, KR Tuttle |
Kidney International | 2002 |
Myocardial fibrosis in transforming growth factor-beta1 (TGF-beta1) transgenic mice is associated with inhibition of interstitial collagenase
U Seeland, C Haeuseler, R Hinrichs, S Rosenkranz, T Pfitzner, K Scharffetter-Kochanek, M Bohm |
European Journal of Clinical Investigation | 2002 |
Towards a biological characterization of focal segmental glomerulosclerosis
P Devarajan, A Spitzer |
American Journal of Kidney Diseases | 2002 |
Renoprotective effects of valsartan and enalapril in STZ-induced diabetes in rats
B Kalender, M Öztürk, M Tunçdemir, Ö Uysal, FK Dağıstanlı, I Yeğenağa, E Erek |
Acta Histochemica | 2002 |
Expression of glomerular plasminogen activator inhibitor type 1 in glomerulonephritis
K Hamano, M Iwano, Y Akai, H Sato, A Kubo, Y Nishitani, H Uyama, Y Yoshida, M Miyazaki, H Shiiki, S Kohno, K Dohi |
American Journal of Kidney Diseases | 2002 |
Effects of Anti-α1 Integrin Subunit Antibody on Anti-Thy-1 Glomerulonephritis
S Kagami, M Urushihara, S Kondo, T Hayashi, H Yamano, K Löster, D Vossmeyer, W Reutter, Y Kuroda |
Laboratory Investigation | 2002 |
Add-on angiotensin II receptor blockade lowers urinary transforming growth factor-β levels
R Agarwal, S Siva, SR Dunn, K Sharma |
American Journal of Kidney Diseases | 2002 |
The spectrum of long-term renal transplantation: Outcomes, complications, and clinical studies
WE Braun, NG Yadlapalli |
Transplantation Reviews | 2002 |
Upregulation of angiotensin II receptors in reflux nephropathy
B Chertin, U Rolle, S Cascio, M McDermot, S O'Briain, A Farkas, P Puri |
Journal of Pediatric Surgery | 2002 |
The Role of the Renin-Angiotensin System in Cholesterol and Puromycin Mediated Renal Injury
S Ghosh, D Sica, AC Schoolwerth, I Fakhry, TW Gehr, RJ Quigg, M Haas |
The American Journal of the Medical Sciences | 2002 |
MUSCLE INJURIES AND REPAIR: CURRENT TRENDS IN RESEARCH
J Huard, Y Li, FH Fu |
The Journal of Bone and Joint Surgery. American volume. | 2002 |
Transforming Growth Factor-β Signal Transduction and Progressive Renal Disease 1
J Cheng, JP Grande |
Experimental biology and medicine (Maywood, N.J.) | 2002 |
Experimental and clinical rationale for use of MMF in nontransplant progressive nephropathies
R Zatz, IL Noronha, CK Fujihara |
American journal of physiology. Renal physiology | 2002 |
High glucose-enhanced activation of mesangial cell p38 MAPK by ET-1, ANG II, and platelet-derived growth factor
E Tsiani, P Lekas, IG Fantus, J Dlugosz, C Whiteside |
American journal of physiology. Endocrinology and metabolism | 2002 |
Angiotensin II induces apoptosis in rat glomerular epithelial cells
G Ding, K Reddy, AA Kapasi, N Franki, N Gibbons, BS Kasinath, PC Singhal |
American journal of physiology. Renal physiology | 2002 |
Angiotensin II stimulates migration of retinal microvascular pericytes: involvement of TGF-β and PDGF-BB
JA Nadal, GM Scicli, LA Carbini, AG Scicli |
American journal of physiology. Heart and circulatory physiology | 2002 |
ACE-I and ARBs in early diabetic nephropathy
M Mauer, B Zinman, R Gardiner, KN Drummond, S Suissa, SM Donnelly, TD Strand, MS Kramer, R Klein, AR Sinaiko |
Journal of Renin-Angiotensin-Aldosterone System | 2002 |
Angiotensin II-Induced Mesangial Cell Apoptosis: Role of Oxidative Stress
S Lodha, D Dani, R Mehta, M Bhaskaran, K Reddy, G Ding, PC Singhal |
Molecular Medicine | 2002 |
Recipient ras gene variants and renal allograft function1:
J Nicod, A Richard, FJ Frey, P Ferrari |
Transplantation | 2002 |
CS-866, a New Angiotensin II Type 1 Receptor Antagonist, Ameliorates Glomerular Anionic Site Loss and Prevents Progression of Diabetic Nephropathy in Otsuka Long-Evans Tokushima Fatty Rats
K Koga, S Yamagishi, M Takeuchi, Y Inagaki, S Amano, T Okamoto, T Saga, Z Makita, M Yoshizuka |
Molecular Medicine | 2002 |
Improving Prognosis for Kidney Disorders
MM Avram |
2002 | |
The Angiotensin Type 1 Receptor Antagonist, Eprosartan, Attenuates the Progression of Renal Disease in Spontaneously Hypertensive Stroke-Prone Rats with Accelerated Hypertension
CT Abrahamsen, FC Barone, WG Campbell, AH Nelson, LC Contino, MA Pullen, ET Grygielko, RM Edwards, NJ Laping, DP Brooks |
The Journal of pharmacology and experimental therapeutics | 2002 |
Inhibition of TGFβ1 by Anti-TGFβ1 Antibody or Lisinopril Reduces Thyroid Fibrosis in Granulomatous Experimental Autoimmune Thyroiditis
K Chen, Y Wei, GC Sharp, H Braley-Mullen |
Journal of immunology (Baltimore, Md. : 1950) | 2002 |
Molecular and Cellular Biology of Neuroprotection in the CNS
C Alzheimer |
2002 | |
The inflammatory component in progressive renal disease—are interventions possible?
IL Noronha, CK Fujihara, R Zatz |
Nephrology Dialysis Transplantation | 2002 |
Variation in the Renin Angiotensin System throughout the Normal Menstrual Cycle
M Chidambaram, JA Duncan, VS Lai, DC Cattran, JS Floras, JW Scholey, JA Miller |
Journal of the American Society of Nephrology : JASN | 2002 |
The genetics of human hypertension
ED Crook |
Seminars in Nephrology | 2002 |
Systemic infusion of angiotensin II into normal rats activates nuclear factor-kappaB and AP-1 in the kidney: role of AT(1) and AT(2) receptors
M Ruiz-Ortega, O Lorenzo, M Rupérez, J Blanco, J Egido |
The American Journal of Pathology | 2001 |
Role of immunocompetent cells in nonimmune renal diseases
B Rodriguez-Iturbe, H Pons, J Herrera-Acosta, RJ Johnson |
Kidney International | 2001 |
Effect of Telmisartan on Angiotensin II-Mediated Collagen Gel Contraction by Adult Rat Cardiac Fibroblasts
PJ Lijnen, VV Petrov, KC Jackson, RH Fagard |
Journal of Cardiovascular Pharmacology | 2001 |
Pathogenesis of diabetic nephropathy: focus on transforming growth factor-β and connective tissue growth factor
OV Sakharova, MW Taal, BM Brenner |
Current Opinion in Nephrology and Hypertension | 2001 |
Evolving strategies for renoprotection: non-diabetic chronic renal disease
MW Taal, BM Brenner |
Current Opinion in Nephrology and Hypertension | 2001 |
Angiotensin II signaling and HB-EGF shedding via metalloproteinase in glomerular mesangial cells
Y Uchiyama-Tanaka, H Matsubara, Y Nozawa, S Murasawa, Y Mori, A Kosaki, K Maruyama, H Masaki, Y Shibasaki, S Fujiyama, A Nose, O Iba, T Hasagawa, E Tateishi, S Higashiyama, T Iwasaka |
Kidney International | 2001 |
Genetic polymorphisms of the renin-angiotensin-aldosterone system in end-stage renal disease
E Lovati, A Richard, BM Frey, FJ Frey, P Ferrari |
Kidney International | 2001 |
New immunosuppressive drugs: an update
E Pohanka |
Current Opinion in Urology | 2001 |
Identification of New Therapies for Leiomyomas: What In Vitro Studies Can Tell Us
RA Nowak |
Clinical Obstetrics and Gynecology | 2001 |
Inhibition of Progression of Heart Failure and Expression of TGF-β1 mRNA in Rats with Heart Failure by the ACE Inhibitor Quinapril
M Ma, K Watanabe, MI Wahed, M Inoue, T Sekiguchi, T Kouda, Y Ohta, M Nakazawa, Y Yoshida, T Yamamoto, H Hanawa, M Kodama, K Fuse, Y Aizawa |
Journal of Cardiovascular Pharmacology | 2001 |
PROTECTIVE ROLE OF ENALAPRIL FOR CHRONIC TUBULOINTERSTITIAL LESIONS OF HYPEROXALURIA
JE Toblli, LN Ferder, IS Stella, M Angerosa, F Inserra |
The Journal of Urology | 2001 |
Non-penetrating Vascular Clips Anastomosis Inhibited Intimal Thickening Under Poor Runoff Conditions in Canine Autogenous Vein Grafts
K Komori, T Shoji, T Furuyama, Y Yonemitsu, E Mori, T Yamaoka, T Matsumoto, K Sugimachi |
European Journal of Vascular and Endovascular Surgery | 2001 |
Increased secretion of TGF-β1 by peripheral blood mononuclear cells from patients with Type 1 diabetes mellitus with diabetic nephropathy
E Korpinen, PH Groop, JA Fagerudd, AM Teppo, HK Åkerblom, O Vaarala |
Diabetic Medicine | 2001 |
IMPAIRED NEPHROGENESIS IN RATS WITH CONGENITAL OBSTRUCTIVE UROPATHY
F Seseke, P Thelen, M Heuser, G Zöller, RH Ringert |
The Journal of Urology | 2001 |
Homozygosity for angiotensinogen 235T variant increases the risk of myocardial infarction in patients with multi-vessel coronary artery disease
O Olivieri, C Stranieri, D Girelli, F Pizzolo, S Grazioli, C Russo, PF Pignatti, R Corrocher |
Journal of Hypertension | 2001 |
Involvement of Angiotensin II in Progression of Renal Injury in Rats With Genetic Non-insulin-Dependent Diabetes Mellitus (Wistar Fatty Rats)
M Noda, T Matsuo, H Nagano, M Ohta, M Sekiguchi, Y Shibouta, T Naka, Y Imura |
The Japanese Journal of Pharmacology | 2001 |
Increased D allele frequency of the angiotensin-converting enzyme gene in pulmonary fibrosis
CD Morrison, AC Papp, AQ Hejmanowski, VM Addis, TW Prior |
Human Pathology | 2001 |
Progression of Chronic Renal Disease
S Klahr |
Heart Disease | 2001 |
High glucose levels enhance TGF-β1–thrombospondin-1 pathway in cultured human mesangial cells via mechanisms dependent on glucose-induced PKC activation
H Tada, K Kuboki, K Nomura, T Inokuchi |
Journal of Diabetes and its Complications | 2001 |
Achieving maximal renal protection in nondiabetic chronic renal disease
MW Taal, BM Brenner |
American Journal of Kidney Diseases | 2001 |
New pharmacologic aspects of CS-866, the newest angiotensin II receptor antagonist
H Koike |
The American Journal of Cardiology | 2001 |
Angiotensin II and the pathophysiology of cardiovascular remodeling
B Williams |
The American Journal of Cardiology | 2001 |
Conditional abatement of tissue fibrosis using nucleoside analogs to selectively corrupt DNA replication in transgenic fibroblasts
M Iwano, A Fischer, H Okada, D Plieth, C Xue, TM Danoff, EG Neilson |
Molecular Therapy | 2001 |
Mechanisms underlying renoprotection during renin-angiotensin system blockade
MW Taal, GM Chertow, HG Rennke, A Gurnani, T Jiang, A Shahsafaei, JL Troy, BM Brenner, HS Mackenzie |
American journal of physiology. Renal physiology | 2001 |
Overexpression of brain natriuretic peptide in mice ameliorates immune-mediated renal injury
T Suganami, M Mukoyama, A Sugawara, K Mori, T Nagae, M Kasahara, K Yahata, H Makino, Y Fujinaga, Y Ogawa, I Tanaka, K Nakao |
Journal of the American Society of Nephrology : JASN | 2001 |
Effect of angiotensin II type 1 receptor blockade on experimental hepatic fibrogenesis
G Paizis, RE Gilbert, ME Cooper, P Murthi, JM Schembri, LL Wu, JR Rumble, DJ Kelly, C Tikellis, A Cox, RA Smallwood, PW Angus |
Journal of Hepatology | 2001 |
Requirement for Tyrosine Kinase-ERK1/2 Signaling in α1β1 Integrin-Mediated Collagen Matrix Remodeling by Rat Mesangial Cells
S Kagami, M Urushihara, S Kondo, K Löster, W Reutter, T Tamaki, M Yoshizumi, Y Kuroda |
Experimental Cell Research | 2001 |
Estrogen-induced cardiorenal protection: potential cellular, biochemical, and molecular mechanisms
RK Dubey, EK Jackson |
American journal of physiology. Renal physiology | 2001 |
Early streptozotocin-diabetes mellitus downregulates rat kidney AT 2 receptors
GJ Wehbi, J Zimpelmann, RM Carey, DZ Levine, KD Burns |
American journal of physiology. Renal physiology | 2001 |
Glomerular hypertension—an under‐appreciated aspect of chronic rejection
LC Paul |
Nephrology Dialysis Transplantation | 2001 |
Renin-angiotensin blockade improves renal cGMP production via non-AT2-receptor mediated mechanisms in hypertension-induced by chronic NOS inhibition in rat
N Uhlenius, O Vuolteenaho, I Tikkanen |
Journal of Renin-Angiotensin-Aldosterone System | 2001 |
Molecular mechanisms of renal allograft fibrosis
JR Waller, ML Nicholson |
The British journal of surgery | 2001 |
alpha-Smooth muscle actin and proliferating cell nuclear antigen expression in focal segmental glomerulosclerosis: functional and structural parameters of renal disease progression
TJ Geleilete, RS Costa, M Dantas, TM Coimbra |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] | 2001 |
Angiotensin II-induced stimulation of collagen secretion and production in cardiac fibroblasts is mediated via angiotensin II subtype 1 receptors
PJ Lijnen, VV Petrov, RH Fagard |
Journal of Renin-Angiotensin-Aldosterone System | 2001 |
TREATMENT OF CHRONIC RENAL ALLOGRAFT REJECTION IN RATS WITH A LOW-MOLECULAR-WEIGHT HEPARIN (REVIPARIN):
C Braun, M Schultz, L Fang, M Schaub, WE Back, D Herr, V Laux, P Rohmeiss, P Schnuelle, FJ van der Woude |
Transplantation | 2001 |
Angiotensin Type 1 Receptor Antagonism and ACE Inhibition Produce Similar Renoprotection in Nω -Nitro- l >-Arginine Methyl Ester/Spontaneously Hypertensive Rats
Y Nakamura, H Ono, X Zhou, ED Frohlich |
Hypertension | 2001 |
Expression and Function of Peroxisome Proliferator–Activated Receptor-γ in Mesangial Cells
SB Nicholas, Y Kawano, S Wakino, AR Collins, WA Hsueh |
Hypertension | 2001 |
ACE Inhibitors and Appearance of Renal Events in Hypertensive Nephrosclerosis
J Segura, C Campo, JL Rodicio, LM Ruilope |
Hypertension | 2001 |
Klinische Endokrinologie und Stoffwechsel
PP Nawroth, R Ziegler |
2001 | |
Role of Mast Cell Tryptase in Renal Interstitial Fibrosis
S Kondo, S Kagami, H Kido, F Strutz, GA Müller, Y Kuroda |
Journal of the American Society of Nephrology : JASN | 2001 |
Aldosterone modulates plasminogen activator inhibitor-1 and glomerulosclerosis in vivo
NJ Brown, S Nakamura, L Ma, I Nakamura, E Donnert, M Freeman, DE Vaughan, AB Fogo |
Kidney International | 2000 |
Renoprotective benefits of RAS inhibition: From ACEI to angiotensin II antagonists
MW Taal, BM Brenner |
Kidney International | 2000 |
Effects of endothelin or angiotensin II receptor blockade on diabetes in the transgenic (mRen-2)27 rat
DJ Kelly, SL Skinner, RE Gilbert, AJ Cox, ME Cooper, JL Wilkinson-Berka |
Kidney International | 2000 |
Lack of evidence of blood pressure-independent protection by renin-angiotensin system blockade after renal ablation
AK Bidani, KA Griffin, G Bakris, MM Picken |
Kidney International | 2000 |
Proinflammatory gene expression and macrophage recruitment in the rat remnant kidney
MW Taal, K Zandi-Nejad, B Weening, A Shahsafaei, S Kato, KW Lee, F Ziai, T Jiang, BM Brenner, HS Mackenzie |
Kidney International | 2000 |
Angiotensin II induces renal oxidant stress in vivo and heme oxygenase-1 in vivo and in vitro
EN Haugen, AJ Croatt, KA Nath |
Kidney International | 2000 |
Cellular and molecular mediators in common pathway mechanisms of chronic renal disease progression
MW Taal, SA Omer, MK Nadim, HS Mackenzie |
Current Opinion in Nephrology and Hypertension | 2000 |
Renal allograft protection with losartan in FisherLewis rats: Hemodynamics, macrophages, and cytokines
F Ziai, H Nagano, M Kusaka, AJ Coito, JL Troy, KC Nadeau, HG Rennke, NL Tilney, BM Brenner, HS Mackenzie |
Kidney International | 2000 |
Role of angiotensin II in diabetic nephropathy
DJ Leehey, AK Singh, N Alavi, R Singh |
Kidney International | 2000 |
ACE inhibitors and angiotensin II antagonists in renal transplantation: An analysis of safety and efficacy
CE Stigant, J Cohen, M Vivera, JS Zaltzman |
American Journal of Kidney Diseases | 2000 |
Calcium channel blockers and angiotensin-converting enzyme inhibitors in the prevention of graft vasculopathy
LC Paul |
The Journal of Heart and Lung Transplantation | 2000 |
CAFFEINE AUGMENTS PROTEINURIA IN PUROMYCIN-AMINONUCLEOSIDE NEPHROTIC RATS1*
SP Tofovic, BR Rominski, S Bastacky, EK Jackson, CK Kost |
Renal Failure | 2000 |
Activated STAT1 suppresses proliferation of cultured rat mesangial cells
O Nakashima, Y Terada, S Hanada, K Yamamoto, M Kuwahara, S Sasaki, F Marumo |
Kidney International | 2000 |
Effect of angiotensin-converting enzyme inhibition on growth factor mRNA in chronic renal allograft rejection in the rat
A Szabo, J Lutz, K Schleimer, B Antus, P Hamar, T Philipp, U Heemann |
Kidney International | 2000 |
Angiotensin II blockade and low-protein diet produce additive therapeutic effects in experimental glomerulonephritis
H Peters, WA Border, NA Noble |
Kidney International | 2000 |
Tandem antifibrotic actions of L-arginine supplementation and low protein diet during the repair phase of experimental glomerulonephritis
H Peters, WA Border, NA Noble |
Kidney International | 2000 |
Vasoactive substances in renal transplantation
D Demetriou, C Wenter, B Watschinger |
Current Opinion in Urology | 2000 |
ANGIOTENSIN II TYPE 1 RECEPTOR ANTAGONIST (LOSARTAN) DOWN-REGULATES TRANSFORMING GROWTH FACTOR-β IN EXPERIMENTAL ACUTE PYELONEPHRITIS
A Khalil, K Tullus, M Bakhiet, LG Burman, G Jaremko, A Brauner |
The Journal of Urology | 2000 |
ANGIOTENSIN II TYPE 1 RECEPTOR ANTAGONIST (LOSARTAN) DOWN-REGULATES TRANSFORMING GROWTH FACTOR-?? IN EXPERIMENTAL ACUTE PYELONEPHRITIS
A Khalil, K Tullus, M Bakhiet, LG Burman, G Jaremko, A Brauner |
The Journal of Urology | 2000 |
Smad proteins and transforming growth factor-beta signaling
M Schiffer, GV Gersdorff, M Bitzer, K Susztak, EP Bottinger |
Kidney International | 2000 |
Plasminogen activator inhibitor type 1 is a potential target in renal fibrogenesis
JP Rerolle, A Hertig, G Nguyen, JD Sraer, EP Rondeau |
Kidney International | 2000 |
Osteopontin expression in progressive renal injury in remnant kidney: Role of angiotensin II
XQ Yu, LL Wu, XR Huang, N Yang, RE Gilbert, ME Cooper, RJ Johnson, KN Lai, HY Lan |
Kidney International | 2000 |
The HOPE Study: practical implications for people with diabetes
B Kennon, M Fisher |
Practical Diabetes International | 2000 |
Activation of transforming growth factor-β1 in diabetic kidney disease
B Hellmich, M Schellner, H Schatz, A Pfeiffer |
Metabolism | 2000 |
Molecular mechanism of diabetic nephropathy
R Lehmann, ED Schleicher |
Clinica Chimica Acta | 2000 |
Role of leukocyte adhesion molecules in monocyte/macrophage infiltration in weanling rats with unilateral ureteral obstruction
A Takeda, A Fukuzaki, H Kaneto, S Ishidoya, Y Ogata, T Sasaki, R Konda, K Sakai, S Orikasa |
International Journal of Urology | 2000 |
TUMOR NECROSIS FACTOR-?? AND TUMOR GROWTH FACTOR-??1 GENOTYPE: PARTIAL ASSOCIATION WITH INTRAGRAFT GENE EXPRESSION IN TWO CASES OF LONG-TERM PERIPHERAL TOLERANCE TO A KIDNEY TRANSPLANT1
WJ Burlingham, PJ O???Connell, LM Jacobson, BN Becker, AD Kirk, V Pravica, IV Hutchinson |
Transplantation | 2000 |
Effects of imidapril and captopril on streptozotocin-induced diabetic nephropathy in mice
M Katoh, Y Ohmachi, Y Kurosawa, H Yoneda, N Tanaka, H Narita |
European Journal of Pharmacology | 2000 |
ACE inhibitors attenuate expression of renal transforming growth factor-β1 in humans
GT Shin, SJ Kim, KA Ma, HS Kim, D Kim |
American Journal of Kidney Diseases | 2000 |
A DNA element in the alpha1 type III collagen promoter mediates a stimulatory response by angiotensin II
GM Ghiggeri, R Oleggini, L Musante, G Caridi, R Gusmano, R Ravazzolo |
Kidney International | 2000 |
Angiotensina II e hipertensión arterial: consecuencias del antagonismo de sus receptores
V Lahera, S Vázquez-Pérez, N las Heras, E Cediel, J Navarro-Cid, V Cachofeiro |
Hipertensión y Riesgo Vascular | 2000 |
Functional and structural correlates of glomerulosclerosis after renal mass reduction in the rat
KA Griffin, MM Picken, M Churchill, P Churchill, AK Bidani |
Journal of the American Society of Nephrology : JASN | 2000 |
Ameliorated glomerular injury in mice overexpressing brain natriuretic peptide with renal ablation
M Kasahara, M Mukoyama, A Sugawara, H Makino, T Suganami, Y Ogawa, M Nakagawa, K Yahata, M Goto, R Ishibashi, N Tamura, I Tanaka, K Nakao |
Journal of the American Society of Nephrology : JASN | 2000 |
Expression of LOX-1, an oxidized low-density lipoprotein receptor, in experimental hypertensive glomerulosclerosis
M Nagase, S Kaname, T Nagase, G Wang, K Ando, T Sawamura, T Fujita |
Journal of the American Society of Nephrology : JASN | 2000 |
Angiotensin II and its receptors in the diabetic kidney
KD Burns |
American Journal of Kidney Diseases | 2000 |
ACE gene polymorphism and renal responsiveness to ACE inhibitors in IgA nephropathy patients
S Y Han, Y J Kwon, S K Jo, J H Shin, D R Cha, W Y Cho, H J Pyo, H K Kim |
The Korean Journal of Internal Medicine | 2000 |
The role of vasoactive compounds, growth factors and cytokines in the progression of renal disease
S Klahr, JJ Morrissey |
Kidney International | 2000 |
Gene expression in rats with renal disease treated with the angiotensin II receptor antagonist, eprosartan
VY Wong, NJ Laping, LC Contino, BA Olson, E Grygielko, DP Brooks |
Physiological genomics | 2000 |
Dietary docosahexaenoic acid ameliorates, but rapeseed oil and safflower oil accelerate renal injury in stroke-prone spontaneously hypertensive rats as compared with soybean oil, which is associated with expression for renal transforming growth factor-β, fibronectin and renin
M Miyazaki, N Takemura, S Watanabe, N Hata, Y Misawa, H Okuyama |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2000 |
Biology of Renal Aging in Humans
B Clark |
Advances in renal replacement therapy | 2000 |
Hexosamine regulation of glucose-mediated laminin synthesis in mesangial cells involves protein kinases A and C
LP Singh, ED Crook |
American journal of physiology. Renal physiology | 2000 |
GLUT‐1 and TGF‐β: the link between hyperglycaemia and diabetic nephropathy
G Gambaro, M Ceol, DD Prete, A D'Angelo |
Nephrology Dialysis Transplantation | 2000 |
Aminopeptidase-A. II. Genomic cloning and characterization of the rat promoter
Q Jiang, M Troyanovskaya, G Jayaraman, DP Healy |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2000 |
Selective estrogen receptor modulators suppress mesangial cell collagen synthesis
J Neugarten, A Acharya, J Lei, S Silbiger |
American journal of physiology. Renal physiology | 2000 |
Should the use of short acting angiotensin-converting enzyme inhibitors be abandoned?
A Erman, G Boner, DJ van Dijk |
Journal of Renin-Angiotensin-Aldosterone System | 2000 |
THE ROLE OF TRANSFORMING GROWTH FACTOR BETA IN CHRONIC RENAL ALLOGRAFT NEPHROPATHY:
S Jain, PN Furness, ML Nicholson |
Transplantation | 2000 |
Blood Pressure–Independent Effects in Rats With Human Renin and Angiotensinogen Genes
E Mervaala, DN Müller, F Schmidt, JK Park, V Gross, M Bader, V Breu, D Ganten, H Haller, FC Luft |
Hypertension | 2000 |
The Kidney and Hypertension in Diabetes Mellitus
CE Mogensen |
2000 | |
Effect of Angiotensin II Blockade on Renal Injury in Mineralocorticoid-Salt Hypertension
M Sorooshian, JL Olson, TW Meyer |
Hypertension | 2000 |
Locally Activated Renin-Angiotensin System Associated with TGF-β1 as a Major Factor for Renal Injury Induced by Chronic Inhibition of Nitric Oxide Synthase in Rats
M Kashiwagi, M Shinozaki, H Hirakata, K Tamaki, T Hirano, M Tokumoto, H Goto, S Okuda, M Fujishima |
Journal of the American Society of Nephrology : JASN | 2000 |
Glycosaminoglycans: Use in Treatment of Diabetic Nephropathy
G Gambaro, FJ Woude |
Journal of the American Society of Nephrology : JASN | 2000 |
Catecholamines and angiotensinogen gene expression in kidney proximal tubular cells
J S Chan, T T Wang, S L Zhang, X Chen, S Carrière |
Molecular and Cellular Biochemistry | 2000 |
Angiotensin II-induced transactivation of epidermal growth factor receptor regulates fibronectin and transforming growth factor-beta synthesis via transcriptional and posttranscriptional mechanisms
RK Dubey, EK Jackson, TF Lüscher |
Journal of Clinical Investigation | 1999 |
Angiotensin II plays a pathogenic role in immune-mediated renal injury in mice
Y Hisada, T Sugaya, M Yamanouchi, H Uchida, H Fujimura, H Sakurai, A Fukamizu, K Murakami |
Journal of Clinical Investigation | 1999 |
Reduced angiotensinogen expression attenuates renal interstitial fibrosis in obstructive nephropathy in mice
RJ Fern, CM Yesko, BA Thornhill, HS Kim, O Smithies, RL Chevalier |
Journal of Clinical Investigation | 1999 |
Communication between myocytes and fibroblasts in cardiac remodeling in angiotensin chimeric mice
T Matsusaka, H Katori, T Inagami, A Fogo, I Ichikawa |
Journal of Clinical Investigation | 1999 |
TGF-beta receptor expression and binding in rat mesangial cells: Modulation by glucose and cyclic mechanical strain
BL Riser, S Ladson-Wofford, A Sharba, P Cortes, K Drake, CJ Guerin, J Yee, ME Choi, PR Segarini, RG Narins |
Kidney International | 1999 |
Renin-angiotensin blockade lowers MCP-1 expression in diabetic rats
S Kato, VA Luyckx, M Ots, KW Lee, F Ziai, JL Troy, BM Brenner, HS Mackenzie |
Kidney International | 1999 |
Pathological Expression of Renin and Angiotensin II in the Renal Tubule after Subtotal Nephrectomy
RE Gilbert, LL Wu, DJ Kelly, A Cox, JL Wilkinson-Berka, CI Johnston, ME Cooper |
The American Journal of Pathology | 1999 |
The concept of glomerular self-defense
M Kitamura, LG Fine |
Kidney International | 1999 |
Effect of candesartan cilexetil (TCV-116) in rats with chronic renal failure
M Noda, T Matsuo, R Fukuda, M Ohta, H Nagano, Y Shibouta, T Naka, K Nishikawa, Y Imura |
Kidney International | 1999 |
Blocking angiotensin II ameliorates proteinuria and glomerular lesions in progressive mesangioproliferative glomerulonephritis
T Nakamura, JE Obata, H Kimura, S Ohno, Y Yoshida, H Kawachi, F Shimizu |
Kidney International | 1999 |
The transforming growth factor beta system in kidney disease and repair: recent progress and future directions
DP Basile |
Current Opinion in Nephrology and Hypertension | 1999 |
Increased levels of transforming growth factor-beta in HIV-associated nephropathy
T Yamamoto, NA Noble, DE Miller, LI Gold, A Hishida, M Nagase, AH Cohen, WA Border |
Kidney International | 1999 |
Angiotensin-converting enzyme gene and diabetes mellitus
B Kennon, JR Petrie, M Small, JM Connell |
Diabetic Medicine | 1999 |
Angiotensin II inhibits interleukin-1beta-induced nitric oxide production in cultured rat mesangial cells
M Kihara, M Yabana, Y Toya, S Kobayashi, T Fujita, T Iwamoto, T Ishigami, S Umemura |
Kidney International | 1999 |
Captopril-induced reduction of serum levels of transforming growth Factor-β1 correlates with long-term renoprotection in insulin-dependent diabetic patients☆☆☆
K Sharma, BO Eltayeb, TA McGowan, SR Dunn, B Alzahabi, R Rohde, FN Ziyadeh, EJ Lewis |
American Journal of Kidney Diseases | 1999 |
TGF-β and fibrosis
MH Branton, JB Kopp |
Microbes and Infection | 1999 |
TGF-β: from latent to active
N Khalil |
Microbes and Infection | 1999 |
Pathophysiological Role of Growth Factors in Diabetic Kidney Disease: Focus on Innovative Therapy
A Flyvbjerg, C Hill, A Logan |
Trends in Endocrinology & Metabolism | 1999 |
Changes in collagenases and TGF-beta precede structural alterations in a model of chronic renal fibrosis
W Mo, C Brecklin, SL Garber, RH Song, AA Pegoraro, J Au, JA Arruda, G Dunea, AK Singh |
Kidney International | 1999 |
Angiotensin II type I receptor antagonist suppresses proteinuria and glomerular lesions in experimental nephritis
T Nagamatsu, K Hayashi, T Oka, Y Suzuki |
European Journal of Pharmacology | 1999 |
New insights into the genetics of preeclampsia
T Morgan, K Ward |
Seminars in Perinatology | 1999 |
Angiotensin II Inhibits Insulin-Induced egr-1 Expression in Mesangial Cells
BT Solow, A Derrien, JA Smith, L Jarett, S Harada |
Archives of Biochemistry and Biophysics | 1999 |
Angiotensin II-induced transactivation of epidermal growth factor receptor regulates fibronectin and transforming growth factor-beta synthesis via transcriptional and posttranscriptional mechanisms
RK Dubey, EK Jackson, TF Lüscher |
Journal of Clinical Investigation | 1999 |
Zonal heterogeneity in action of angiotensin-converting enzyme inhibitor on renal microcirculation: role of intrarenal bradykinin
H Matsuda, K Hayashi, K Arakawa, M Naitoh, E Kubota, M Honda, A Matsumoto, H Suzuki, T Yamamoto, F Kajiya, T Saruta |
Journal of the American Society of Nephrology : JASN | 1999 |
Juxtaglomerular cell tumor with retroperitoneal fibrosis and secondary immune-complex glomerulonephritis: A possible contribution of the renin angiotensin system to renal fibrosis
H Moriya, A Ishida, I Nakabayashi, J Nishiyama, S Kobayashi |
American Journal of Kidney Diseases | 1999 |
Remission of nephrotic syndrome in type 1 diabetes: Long-term follow-up of patients in the Captopril Study
WA Wilmer, LA Hebert, EJ Lewis, RD Rohde, F Whittier, D Cattran, AS Levey, JB Lewis, S Spitalewitz, S Blumenthal, RP Bain |
American Journal of Kidney Diseases | 1999 |
Sodium bicarbonate treatment reduces renal injury, renal production of transforming growth Factor-β, and urinary transforming growth Factor-β excretion in rats with doxorubicin-induced nephropathy
EA Baroni, RS Costa, R Volpini, TM Coimbra |
American Journal of Kidney Diseases | 1999 |
Association of TGF-beta signaling in angiotensin II-induced PAI-1 mRNA upregulation in mesangial cells: role of PKC
M Motojima, J Kakuchi, T Yoshioka |
Biochimica et Biophysica Acta | 1999 |
Transforming growth factor beta activity in urine of patients with type 2 diabetes and diabetic nephropathy
EW Rivarola, M Moyses-Neto, M Dantas, CG da-Silva, R Volpini, TM Coimbra |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] | 1999 |
LDL stimulates collagen mRNA synthesis in mesangial cells through induction of PKC and TGF-β expression
HS Lee, BC Kim, HK Hong, YS Kim |
American journal of physiology. Renal physiology | 1999 |
Angiotensin II (ATII)-inducible Platelet-derived Growth Factor A-chain Gene Expression Is p42/44 Extracellular Signal-regulated Kinase-1/2 and Egr-1-dependent and Mediated via the ATII Type 1 but Not Type 2 Receptor: INDUCTION BY ATII ANTAGONIZED BY NITRIC OXIDE
FL Day, LA Rafty, CN Chesterman, LM Khachigian |
The Journal of biological chemistry | 1999 |
CYCLOSPORINE-INDUCED INTERSTITIAL FIBROSIS AND ARTERIOLAR TGF-?? EXPRESSION WITH PRESERVED RENAL BLOOD FLOW:
JM Vieira, IL Noronha, DM Malheiros, EA Burdmann |
Transplantation | 1999 |
Angiotensin II Stimulates Collagen Synthesis in Human Vascular Smooth Muscle Cells: Involvement of the AT 1 Receptor, Transforming Growth Factor-β, and Tyrosine Phosphorylation
CM Ford, S Li, JG Pickering |
Arteriosclerosis, thrombosis, and vascular biology | 1999 |
Interaction of Angiotensin II and Mechanical Stretch on Vascular Endothelial Growth Factor Production by Human Mesangial Cells
G Gruden, S Thomas, DA Burt, W Zhou, G Chusney, L Gnudi, G VIBERTI |
Journal of the American Society of Nephrology : JASN | 1999 |
Ischaemic nephropathy—is the diagnosis excluded by heavy proteinuria?
AD Makanjuola, JE Scoble |
Nephrology Dialysis Transplantation | 1999 |
Acute and Chronic Renal Effects of Recombinant Human TGF-β2 in the Rat
FJ Kelly, S Anderson, MM Thompson, TT Oyama, TM Kennefick, CL Corless, RJ Roman, L Kurtzberg, BM Pratt, SR Ledbetter |
Journal of the American Society of Nephrology : JASN | 1999 |
α1β1 Integrin-Mediated Collagen Matrix Remodeling by Rat Mesangial Cells Is Differentially Regulated by Transforming Growth Factor-β and Platelet-Derived Growth Factor-BB
S Kagami, S Kondo, K Löster, W Reutter, T Kuhara, K Yasutomo, Y Kuroda |
Journal of the American Society of Nephrology : JASN | 1999 |
Autocrine and paracrine mechanisms in the early stages of diabetic nephropathy
G Pugliese, F Pricci, G Romeo, G Leto, L Amadio, C Iacobini, UD Mario |
Journal of Endocrinological Investigation | 1999 |
Signal transduction in hepatic stellate cells
DE Clouthier, SA Comerford, RE Hammer |
Journal of Clinical Investigation | 1998 |
High glucose-induced transforming growth factor beta1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells
V Kolm-Litty, U Sauer, A Nerlich, R Lehmann, ED Schleicher |
Journal of Clinical Investigation | 1998 |
A new model of diabetic nephropathy with progressive renal impairment in the transgenic (mRen-2)27 rat (TGR)
DJ Kelly, JL Wilkinson-Berka, TJ Allen, ME Cooper, SL Skinner |
Kidney International | 1998 |
Angiotensin II induces superoxide anion production by mesangial cells
EA Jaimes, JM Galceran, L Raij |
Kidney International | 1998 |
Serotonin enhances the production of type IV collagen by human mesangial cells
M Kasho, M Sakai, T Sasahara, Y Anami, T Matsumura, T Takemura, H Matsuda, S Kobori, M Shichiri |
Kidney International | 1998 |
Sequential effects of high glucose on mesangial cell transforming growth factor-β1 and fibronectin synthesis
JH Oh, H Ha, MR Yu, HB Lee |
Kidney International | 1998 |
Protective Effects of CGS 30440, a Combined Angiotensin-Converting Enzyme Inhibitor and Neutral Endopeptidase Inhibitor, in a Model of Chronic Renal Failure
DS Cohen, JE Mathis, RA Dotson, SR Graybill, NJ Wosu |
Journal of Cardiovascular Pharmacology | 1998 |
Renal effects of renin—angiotensin
M Franco, R Paniagua, J Herrera-Acosta |
Current Opinion in Nephrology and Hypertension | 1998 |
RENAL ANGIOTENSIN CONVERTING ENZYME PROMOTES RENAL DAMAGE DURING URETERAL OBSTRUCTION
BJ Stoneking, TE Hunley, H Nishimura, J Ma, A Fogo, T Inagami, M Tamura, MC Adams, JW Brock, V Kon |
The Journal of Urology | 1998 |
Targeting TGF-beta overexpression in renal disease: Maximizing the antifibrotic action of angiotensin II blockade
H Peters, WA Border, NA Noble |
Kidney International | 1998 |
Signal transduction in hepatic stellate cells
DE Clouthier, SA Comerford, RE Hammer |
Journal of Clinical Investigation | 1998 |
Transforming growth factor-β (TGF-β) activity in urine of patients with glomerulonephritis is related to their renal functional and structural changes
G Dominguez, R Costa, M Dantas, T Kimachi, C Piuci, T Coimbra |
Nephrology | 1998 |
Genetic polymorphisms of the renin-angiotensin system and the outcome of focal segmental glomerulosclerosis in children
Y Frishberg, R Becker-Cohen, D Halle, E Feigin, B Eisenstein, R Halevy, D Lotan, I Juabeh, N Ish-Shalom, D Magen, Y Shvil, L Sinai-Treiman, A Drukker |
Kidney International | 1998 |
Angiotensin converting enzyme inhibition reduces the expression of transforming growth factor-β1 and type IV collagen in diabetic vasculopathy
JR Rumble, RE Gilbert, A Cox, L Wu, ME Cooper |
Journal of Hypertension | 1998 |
Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis
SE Thomas, TF Andoh, RH Pichler, SJ Shankland, WG Couser, WM Bennett, RJ Johnson |
Kidney International | 1998 |
Mesangiolytic glomerulopathy in severe congestive heart failure
H Yoshida, M Yashiro, P Liang, E Muso, E Takeuchi, T Shimada, KI Sekita, T Ono, K Kanatsu, T Sugiyama, C Kawai, S Sasayama |
Kidney International | 1998 |
Upper urinary tract obstruction: experimental and clinical aspects
NGUYEN, KOGAN |
BJU International | 1998 |
Collagen Type I Modulates the Platelet-Derived Growth Factor (PDGF) Regulation of the Growth and Expression of β1 Integrins by Rat Mesangial Cells
S Kagami, S Kondo, K Löster, W Reutter, M Urushihara, A Kitamura, S Kobayashi, Y Kuroda |
Biochemical and Biophysical Research Communications | 1998 |
Significant Role of the Increase in Renin-Angiotensin System in Cardiac Hypertrophy and Renal Glomerular Sclerosis in Double Transgenic Tsukuba Hypertensive Mice Carrying Both Human Renin and Angiotensinogen Genes
T Kai, H Kino, K Sugimura, S Shimada, A Kurooka, KI Akamatsu, T Takenaka, A Fukamizu, K Murakami, K Ishikawa, R Katori |
Clinical and Experimental Hypertension | 1998 |
Efficacy and safety of losartan in the treatment of hypertension in renal transplant recipients
D Castillo, JM Campistol, L Guirado, L Capdevilla, JG Martinez, P Pereira, J Bravo, R Perez |
Kidney International | 1998 |
Attenuation of diabetes-associated mesenteric vascular hypertrophy with perindopril: Morphological and molecular biological studies
ME Cooper, Z Cao, JR Rumble, K Jandeleit, TJ Allen, RE Gilbert |
Metabolism | 1998 |
Pathophysiology of diabetic nephropathy
ME Cooper, RE Gilbert, M Epstein |
Metabolism | 1998 |
Renal expression of transforming growth factor-beta inducible gene-h3 (beta ig-h3) in normal and diabetic rats
RE Gilbert, JL Wilkinson-Berka, DW Johnson, A Cox, T Soulis, LL Wu, DJ Kelly, G Jerums, CA Pollock, ME Cooper |
Kidney International | 1998 |
Angiotensin-converting Enzyme Inhibition Delays Pulmonary Vascular Neointimal Formation
K Okada, ML Bernstein, W Zhang, DP Schuster, MD Botney |
American journal of respiratory and critical care medicine | 1998 |
Strategies to prolong long-term renal allograft function
JA Velosa |
Transplantation Reviews | 1998 |
A central role for protein kinase C overactivity in diabetic glomerulosclerosis: implications for prevention with antioxidants, fish oil, and ACE inhibitors
MF McCarty |
Medical Hypotheses | 1998 |
The use of angiotensin-converting enzyme inhibitors in renal transplant patients
LC Paul, J Zaltzman |
Transplantation Reviews | 1998 |
Combined treatments with Ninjin-youei-to (Ren-shen-yang-rong-tang) plus a suboptimal dose of prednisolone on autoimmune nephritis in MRL\lpr mice
S Nakai, T Kawakita, K Himeno, K Nomoto |
International Journal of Immunopharmacology | 1998 |
Early induction of transforming growth factor-beta via angiotensin II type 1 receptors contributes to cardiac fibrosis induced by long-term blockade of nitric oxide synthesis in rats
H Tomita, K Egashira, Y Ohara, M Takemoto, M Koyanagi, M Katoh, H Yamamoto, K Tamaki, H Shimokawa, A Takeshita |
Hypertension | 1998 |
Transforming growth factor-β1 hyperexpression in African American end-stage renal disease patients
M Suthanthiran, A Khanna, D Cukran, R Adhikarla, VK Sharma, T Singh, P August |
Kidney International | 1998 |
Glycated albumin stimulates fibronectin gene expression in glomerular mesangial cells: Involvement of the transforming growth factor-β system
FN Ziyadeh, DC Han, JA Cohen, J Guo, MP Cohen |
Kidney International | 1998 |
TGF-β type II receptor in rat renal vascular development: Localization to juxtaglomerular cells
A Liu, BJ Ballermann |
Kidney International | 1998 |
Tissue Angiotensin II Concentration in the Heart and Kidneys in Transgenic Tsukuba Hypertensive Mice
TK Atsuh |
Blood Pressure | 1998 |
Transforming growth factor β1 and renal disease in African Americans
S Klahr |
Kidney International | 1998 |
Mechanism of Angiotensin II-mediated Regulation of Fibronectin Gene in Rat Vascular Smooth Muscle Cells
K Tamura, N Nyui, N Tamura, T Fujita, M Kihara, Y Toya, I Takasaki, N Takagi, M Ishii, K Oda, M Horiuchi, S Umemura |
The Journal of biological chemistry | 1998 |
Dietary salt modulates renal production of transforming growth factor-β in rats
WZ Ying, PW Sanders |
American journal of physiology. Renal physiology | 1998 |
Salt Induces Myocardial and Renal Fibrosis in Normotensive and Hypertensive Rats
HC Yu, LM Burrell, MJ Black, LL Wu, RJ Dilley, ME Cooper, CI Johnston |
Circulation | 1998 |
Factors Influencing Arteriovenous Fistula Dysfunction in Japanese Patients on Chronic Hemodialysis
T Masaki, N Yorioka, Y Kyuden, K Yamashita, Y Taniguchi, M Yamakido, J Tanaka, S Harada |
The International Journal of Artificial Organs | 1998 |
Interactions of Transforming Growth Factor-β and Angiotensin II in Renal Fibrosis
WA Border, NA Noble |
Hypertension | 1998 |
Transcription-Modulating Drugs: A New Frontier in the Treatment of Essential Hypertension
TW Kurtz, DG Gardner |
Hypertension | 1998 |
Vascular hypertrophy in experimental diabetes. Role of advanced glycation end products
JR Rumble, ME Cooper, T Soulis, A Cox, L Wu, S Youssef, M Jasik, G Jerums, RE Gilbert |
Journal of Clinical Investigation | 1997 |
Association of angiotensinogen gene T235 variant with progression of immunoglobin A nephropathy in Caucasian patients
Y Pei, J Scholey, K Thai, M Suzuki, D Cattran |
Journal of Clinical Investigation | 1997 |
The renoprotective properties of angiotensin-converting enzyme inhibitors in a chronic model of membranous nephropathy are solely due to the inhibition of angiotensin II: Evidence based on comparative studies with a receptor antagonist
C Zoja, R Donadelli, D Corna, D Testa, D Facchinetti, R Maffi, E Luzzana, V Colosio, T Bertani, G Remuzzi |
American Journal of Kidney Diseases | 1997 |
Modulation of plasminogen activator inhibitor-1 in vivo: A new mechanism for the anti-fibrotic effect of renin-angiotensin inhibition
T Oikawa, M Freeman, W Lo, DE Vaughan, A Fogo |
Kidney International | 1997 |
Tyrosine kinase dependent expression of TGF-β induced by stretch in mesangial cells
M Hirakata, S Kaname, UG Chung, N Joki, Y Hori, M Noda, Y Takuwa, T Okazaki, T Fujita, T Katoh, K Kurokawa |
Kidney International | 1997 |
The role of angiotensin II in diabetic nephropathy: Emphasis on nonhemodynamic mechanisms
G Wolf, FN Ziyadeh |
American Journal of Kidney Diseases | 1997 |
Angiotensin II and L-arginine in tissue fibrosis: More than blood pressure
H Peters, NA Noble |
Kidney International | 1997 |
Therapeutic approaches to organ fibrosis
TJ Franklin |
The International Journal of Biochemistry & Cell Biology | 1997 |
Transforming growth factor βs and wound healing
S O'Kane, MW Ferguson |
The International Journal of Biochemistry & Cell Biology | 1997 |
Renal artery stenosis and unilateral focal and segmental glomerulosclerosis
AM Alkhunaizi, A Chapman |
American Journal of Kidney Diseases | 1997 |
Role of transforming growth factor-β1 during glomerulosclerosis in rats with reduced renal mass
T Konta, N Degawa, S Kato, H Tomoike |
Clinical and Experimental Nephrology | 1997 |
Dual effects of angiotensin II on the plasminogen/plasmin system in rat mesangial cells
S Kagami, T Kuhara, K Okada, Y Kuroda, WA Border, NA Noble |
Kidney International | 1997 |
Potential Risk Factors Associated With Progressive Renal Damage in Childhood Urological Diseases
JW Brock, M Adams, T Hunley, A Wada, L Trusler, V Kon |
The Journal of Urology | 1997 |
BIOLOGICAL FUNCTIONS OF ANGIOTENSIN AND ITS RECEPTORS
T Matsusaka, I Ichikawa |
Annual Review of Physiology | 1997 |
Potential Risk Factors Associated With Progressive Renal Damage in Childhood Urological Diseases: The Role of Angiotensin-Converting Enzyme Gene Polymorphism
JW Brock, M Adams, T Hunley, A Wada, L Trusler, V Kon |
The Journal of Urology | 1997 |
Latent transforming growth factor-β: Structural features and mechanisms of activation
JS Munger, JG Harpel, PE Gleizes, R Mazzieri, I Nunes, DB Rifkin |
Kidney International | 1997 |
Growth factor antagonists for the treatment of diabetic vascular complications
RG Tilton, RA Dixon, TA Brock |
Expert Opinion on Investigational Drugs | 1997 |
MECHANISM OF FIBROSIS IN EXPERIMENTAL TACROLIMUS NEPHROTOXICITY1,2
FS Shihab, WM Bennett, AM Tanner, TF Andoh |
Transplantation | 1997 |
Sodium depletion enhances fibrosis and the expression of TGF-β1 and matrix proteins in experimental chronic cyclosporine nephropathy
FS Shihab, TF Andoh, AM Tanner, WM Bennett |
American Journal of Kidney Diseases | 1997 |
The effect of angiotensin II on plasminogen activator(PA) system in mesangial cells: the role of renin-angiotensin system in the regulation of glomerular extracellular matrix metabolism
S Kagami, T Kuhara, K Yasutomo, K Okada, S Kondo, M Urusihara, Y Morimoto, Y Kuroda |
Nihon Shoni Jinzobyo Gakkai Zasshi | 1997 |
Tacrolimus (FK506)-Associated Renal Pathology
PS Randhawa, TE Starzl, AJ Demetris |
Advances in Anatomic Pathology | 1997 |
Synergistic effect of angiotensin II type 1 receptor genotype and poor glycaemic control on risk of nephropathy in IDDM
A Doria, T Onuma, JH Warram, AS Krolewski |
Diabetologia | 1997 |
Transforming growth factor β1 and renal injury following subtotal nephrectomy in the rat: Role of the renin-angiotensin system
LL Wu, A Cox, CJ Roe, M Dziadek, ME Cooper, RE Gilbert |
Kidney International | 1997 |
Antioxidant inhibition of protein kinase C—signaled increases in transforming growth factor-beta in mesangial cells
RK Studer, PA Craven, FR Derubertis |
Metabolism | 1997 |
Imidapril inhibits increased transforming growth factor-β1 expression in remnant kidney model
A Hamaguchi, S Kim, H Wanibuchi, H Iwao |
European Journal of Pharmacology | 1997 |
Plasma angiotensin II concentrations and the effect of treatment with enalapril in dogs with proteinuria due to renal disease
CJ Piek, HP Meyer |
Veterinary Quarterly | 1997 |
Transforming growth factor-β, other growth factors, and the extracellular matrix
MA Haralson |
Journal of Laboratory and Clinical Medicine | 1997 |
Angiotensin II modulates cell growth-related events and synthesis of matrix proteins in renal interstitial fibroblasts
M Ruiz-Ortega, J Egido |
Kidney International | 1997 |
Progression of renal damage in human glomerulonephritides: Is there sleight of hand in winning the game?
FP Schena, L Gesualdo, G Grandaliano, V Montinaro |
Kidney International | 1997 |
Angiotensin II blockade decreases TGF-β1 and matrix proteins in cyclosporine nephropathy
FS Shihab, WM Bennett, AM Tanner, TF Andoh |
Kidney International | 1997 |
Microalbuminuria: A Marker to Increased Renal and Cardiovascular Risk in Diabetes Mellitus
K McKenna, C Thompson |
Scottish Medical Journal | 1997 |
Bimodal Effects of Angiotensin II on Migration of Human and Rat Smooth Muscle Cells: Direct Stimulation and Indirect Inhibition Via Transforming Growth Factor-β1
G Liu, E Espinosa, BS Oemar, TF Lüscher |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
Dual Effects of Lisinopril on Puromycin Aminonucleoside Nephrosis in Unilaterally Nephrectomized Rats
T Shinosaki, I Takagawa, N Sunagawa, Y Yonetani, H Kurihara |
The Japanese Journal of Pharmacology | 1997 |
Cigarette smoke increases gastric ulcer size in part by an angiotensin II-mediated mechanism in rats
K Seno, J H Zhu, J D Barrett, P Eggena, O U Scremin, K Lam, J W Leung, F W Leung |
Digestive Diseases and Sciences | 1997 |
Regulation of extracellular matrix by mechanical stress in rat glomerular mesangial cells
T Yasuda, S Kondo, T Homma, RC Harris |
Journal of Clinical Investigation | 1996 |
Extracellular matrix, growth factors and their interactions in the pathogenesis of diabetic kidney disease
RE GILBERT, ME COOPER, G JERUMS |
Nephrology | 1996 |
Insulin and angiotensin II are additive in stimulating TGF-β1 and matrix mRNAs in mesangial cells
PW Anderson, XY Zhang, J Tian, JD Correale, XP Xi, D Yang, K Graf, RE Law, WA Hsueh |
Kidney International | 1996 |
Transforming Growth Factor β in Diabetic Nephropathy
WA Border, T Yamamoto, NA Noble |
Diabetes/Metabolism Reviews | 1996 |
Vasoactive hormones and renal sclerosis
J Egido |
Kidney International | 1996 |
Polymorphisms of the renin-angiotensin system genes in progressive renal diseases
H Yoshida, V Kon, I Ichikawa |
Kidney International | 1996 |
Angiotensinogen: Molecular biology, biochemistry and physiology
L Morgan, FB Pipkin, N Kalsheker |
The International Journal of Biochemistry & Cell Biology | 1996 |
Intragraft TGF-β1 mRNA: A correlate of interstitial fibrosis and chronic allograft nephropathy
VK Sharma, RM Bologa, GP Xu, B Li, J Mouradian, J Wang, D Serur, V Rao, M Suthanthiran |
Kidney International | 1996 |
Role of transforming growth factor-β1 in experimental chronic cyclosporine nephropathy
FS Shihab, TF Andoh, AM Tanner, NA Noble, WA Border, N Franceschini, WM Bennett |
Kidney International | 1996 |
Cyclic stretching force selectively up-regulates transforming growth factor-beta isoforms in cultured rat mesangial cells
BL Riser, P Cortes, C Heilig, J Grondin, S Ladson-Wofford, D Patterson, RG Narins |
The American Journal of Pathology | 1996 |
Advances in Structural Biology
A Ghahary, P Rajeet, EE Tredget |
Advances in Structural Biology | 1996 |
Enhanced renal sensitivity to angiotensin actions in diabetes mellitus in the rat
J Zimpelmann, D Kumar, DZ Levine, G Wehbi, JD Imig, LG Navar, KD Burns |
The American journal of physiology | 1996 |
Therapy of Idiopathic Membranous Nephropathy
G Rostoker, B Weil |
Clinical immunotherapeutics | 1996 |
Enhanced renal sensitivity to angiotensin actions in diabetes mellitus in the rat
J Zimpelmann, D Kumar, DZ Levine, G Wehbi, JD Imig, LG Navar, KD Burns |
The American journal of physiology | 1996 |
Angiotensin II induction of fibronectin biosynthesis in cultured human mesangial cells: Association with CREB transcription factor activation
NS Nahman, KL Rothe, ME Falkenhain, KM Frazer, LE Dacio, JD Madia, KL Leonhart, JC Kronenberger, DA Stauch |
Journal of Laboratory and Clinical Medicine | 1996 |
Effects and Interactions of Endothelin-1 and Angiotensin II on Matrix Protein Expression and Synthesis and Mesangial Cell Growth
D Gómez-Garre, M Ruiz-Ortega, M Ortego, R Largo, MJ López-Armada, JJ Plaza, E González, J Egido |
Hypertension | 1996 |
Pressure and Angiotensin II Synergistically Induce Aortic Fibronectin Expression in Organ Culture Model of Rabbit Aorta: Evidence for a Pressure-Induced Tissue Renin-Angiotensin System
N Bardy, R Merval, J Benessiano, JL Samuel, A Tedgui |
Circulation research | 1996 |
Extracellular matrix and the kidney
PN Furness |
Journal of clinical pathology | 1996 |
ACE Inhibitors and the Kidney: A Risk-Benefit Assessment
G Navis, HJ Faber, D de Zeeuw, PE de Jong |
Drug Safety | 1996 |
Gene targeting in mice reveals a requirement for angiotensin in the development and maintenance of kidney morphology and growth factor regulation
F Niimura, PA Labosky, J Kakuchi, S Okubo, H Yoshida, T Oikawa, T Ichiki, AJ Naftilan, A Fogo, T Inagami |
Journal of Clinical Investigation | 1995 |
Angiotensin II receptor subtypes in the kidney: Distribution and function
J ZHUO, D ALCORN, PJ HARRIS, J McCAUSLAND, GP ALDRED, FA MENDELSOHN |
Nephrology | 1995 |
Proteoglycan synthesis by bovine myocardial endothelial cells is increased by long-term exposure to high concentrations of glucose
DJ Klein, RM Cohen, Z Rymaszewski |
Journal of Cellular Physiology | 1995 |
ACE inhibition reduces proteinuria, glomerular lesions and extracellular matrix production in a normotensive rat model of immune complex nephritis
M Ruiz-Ortega, S González, D Serón, E Condom, C Bustos, R Largo, E González, A Ortiz, J Egido |
Kidney International | 1995 |
ACE inhibition prevents renal failure and death in uninephrectomized MWF/Ztm rats
A Remuzzi, A Benigni, B Malanchini, I Bruzzi, C Foglieni, G Remuzzi |
Kidney International | 1995 |
Angiotensin receptors: Physiology and pharmacology
GP Guthrie |
Clinical Cardiology | 1995 |
Protein kinase C signals thromboxane induced increases in fibronectin synthesis and TGF-β bioactivity in mesangial cells
RK Studer, H Negrete, PA Craven, FR DeRubertis |
Kidney International | 1995 |
Protein kinase C in diabetic nephropathy
PA Craven, RK Studer, H Negrete, FR DeRubertis |
Journal of Diabetes and its Complications | 1995 |
Angiotensin II stimulates the autocrine production of transforming growth factor-β1 in adult rat cardiac fibroblasts
AA Lee, WH Dillmann, AD McCulloch, FJ Villarreal |
Journal of Molecular and Cellular Cardiology | 1995 |
Tissue Renin-Angiotensin Systems
AK Mukhopadhyay, MK Raizada |
1995 | |
Thromboxane stimulation of mesangial cell fibronectin synthesis is signalled by protein kinase C and modulated by cGMP
RK Studer, PA Craven, FR DeRubertis |
Kidney International | 1994 |
Increased glomerular capillary pressure alters glomerular cytokine expression
SJ Shankland, H Ly, K Thai, JW Scholey |
Circulation research | 1994 |
Lewis A. Conner Memorial Lecture. Mechanisms leading to myocardial infarction: insights from studies of vascular biology
V Fuster |
Circulation | 1994 |