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Glucose-induced protein kinase C activity regulates arachidonic acid release and eicosanoid production by cultured glomerular mesangial cells.

B Williams, R W Schrier

B Williams, R W Schrier

Published December 1, 1993
Citation Information: J Clin Invest. 1993;92(6):2889-2896. https://doi.org/10.1172/JCI116911.

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Quantitative Profiling of DNA Damage and Apoptotic Pathways in UV Damaged Cells Using PTMScan Direct MP Stokes, JC Silva, X Jia, KA Lee, RD Polakiewicz, MJ Comb	International journal of molecular sciences	2012
Assessing developmental roles of MKK4 and MKK7 in vitro J Wang, Y Xia	Communicative & integrative biology	2012
Specificity of linear motifs that bind to a common mitogen-activated protein kinase docking groove Á Garai, A Zeke, G Gógl, I Törő, F Fördős, H Blankenburg, T Bárkai, J Varga, A Alexa, D Emig, M Albrecht, A Reményi	Science signaling	2012
Phosphorylated mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 may not always represent its kinase activity in a rat model of focal cerebral ischemia with or without ischemic preconditioning T Takahashi, GK Steinberg, H Zhao	Neuroscience	2012
MLK4β functions as a negative regulator of MAPK signaling and cell invasion WF Saab, MS Brown, DN Chadee	Oncogenesis	2012
Unique gene alterations are induced in FACS-purified Fos-positive neurons activated during cue-induced relapse to heroin seeking S Fanous, DH Guez-Barber, EM Goldart, R Schrama, FR Theberge, Y Shaham, BT Hope	Journal of Neurochemistry	2012
Human adipose tissue-derived multilineage progenitor cells exposed to oxidative stress induce neurite outgrowth in PC12 cells through p38 MAPK signaling M Moriyama, H Moriyama, A Ueda, Y Nishibata, H Okura, A Ichinose, A Matsuyama, T Hayakawa	BMC cell biology	2012
p38α MAPK regulates myocardial regeneration in zebrafish C Jopling, G Suñe, C Morera, JC Belmonte	Cell cycle (Georgetown, Tex.)	2012
Morphine decreases bacterial phagocytosis by inhibiting actin polymerization through cAMP-, Rac-1-, and p38 MAPK-dependent mechanisms J Ninković, S Roy	The American Journal of Pathology	2012
Decreased collagen-induced arthritis severity and adaptive immunity in MKK-6-deficient mice D Hammaker, K Topolewski, M Edgar, T Yoshizawa, A Fukushima, DL Boyle, EC Burak, RL Sah, GS Firestein	Arthritis & Rheumatism	2012
p38α MAPK regulates myocardial regeneration in zebrafish C Jopling, G Suñè, C Morera, JC Belmote	Cell cycle (Georgetown, Tex.)	2012
Decreased collagen-induced arthritis severity and adaptive immunity in mitogen activated protein kinase kinase 6 -deficient mice D Hammaker, K Topolewski, M Edgar, T Yoshizawa, A Fukushima, DL Boyle, GS Firestein	Arthritis & Rheumatism	2012
Caenorhabditis elegans mom-4 is required for the activation of the p38 MAPK signaling pathway in the response to Pseudomonas aeruginosa infection A Xu, G Shi, F Liu, B Ge	Protein & Cell	2012
A review of the mammalian unfolded protein response A Chakrabarti, AW Chen, JD Varner	Biotechnology and Bioengineering	2011
A Cytoplasmic Negative Regulator Isoform of ATF7 Impairs ATF7 and ATF2 Phosphorylation and Transcriptional Activity J Diring, B Camuzeaux, M Donzeau, M Vigneron, M Rosa-Calatrava, C Kedinger, B Chatton, PA Defossez	PloS one	2011
Ipomoea batatas and Agarics blazei ameliorate diabetic disorders with therapeutic antioxidant potential in streptozotocin-induced diabetic rats A Niwa, T Tajiri, H Higashino	Journal of Clinical Biochemistry and Nutrition	2011
Targeting lentiviral vectors for cancer immunotherapy F Arce, K Breckpot, M Collins, D Escors	Current cancer therapy reviews	2011
Enhancive effects of d-glucose and its analogs on expression of d-glucose-unrelated transgenes in mammalian cells M Kimura, H Namba, M Okubo, M Ezumi, N Susumu, M Yamada, Y Arao	Journal of Bioscience and Bioengineering	2011
MK2 SUMOylation regulates actin filament remodeling and subsequent migration in endothelial cells by inhibiting MK2 kinase and HSP27 phosphorylation E Chang, KS Heo, CH Woo, H Lee, NT Le, TN Thomas, K Fujiwara, J Abe	Blood	2011
Manganese modulation of MAPK pathways: effects on upstream mitogen activated protein kinase kinases (MKKs) and mitogen activated kinase phosphatase-1 (MKP-1) in microglial cells PL Crittenden, NM Filipov	Journal of applied toxicology : JAT	2011
Regulation of JNK activity in the apoptotic response of intestinal epithelial cells RM Ray, S Jin, MN Bavaria, LR Johnson	AJP Gastrointestinal and Liver Physiology	2011
Loss of ATF2 Function Leads to Cranial Motoneuron Degeneration during Embryonic Mouse Development J Ackermann, G Ashton, S Lyons, D James, JP Hornung, N Jones, W Breitwieser	PloS one	2011
Role of β-Catenin in Post-Meiotic Male Germ Cell Differentiation YF Chang, JS Lee-Chang, KY Harris, AP Sinha-Hikim, MK Rao	PloS one	2011
Analysis of the Mitogen-activated protein kinase kinase 4 (MAP2K4) tumor suppressor gene in ovarian cancer SJ Davis, DY Choong, M Ramakrishna, GL Ryland, IG Campbell, KL Gorringe	BMC Cancer	2011
LZAP Inhibits p38 MAPK (p38) Phosphorylation and Activity by Facilitating p38 Association with the Wild-Type p53 Induced Phosphatase 1 (WIP1) H An, X Lu, D Liu, WG Yarbrough	PloS one	2011
Extracellular Signal-Regulated Kinase (ERK) Activation and Mitogen-Activated Protein Kinase Phosphatase 1 Induction by Pulsatile Gonadotropin-Releasing Hormone in Pituitary Gonadotrophs H Kanasaki, I Purwana, A Oride, T Mijiddorj, K Miyazaki	Journal of Signal Transduction	2011
p38 MAPK-mediated regulation of Xbp1s is crucial for glucose homeostasis J Lee, C Sun, Y Zhou, J Lee, D Gokalp, H Herrema, SW Park, RJ Davis, U Ozcan	Nature Medicine	2011
Alpinetin suppresses proliferation of human hepatoma cells by the activation of MKK7 and elevates sensitization to cis-diammined dichloridoplatium B Tang, J Du, J Wang, G Tan, Z Gao, Z Wang, L Wang	Oncology reports	2011
Ziram activates mitogen-activated protein kinases and decreases cytolytic protein levels in human natural killer cells TR Taylor, MM Whalen	Toxicology Mechanisms and Methods	2011
Activation of mitogen-activated protein kinases by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) plays an important role in macrophage stimulation J Sun, LC Wang, ZG Fridlender, V Kapoor, G Cheng, LM Ching, SM Albelda	Biochemical Pharmacology	2011
cPLA(2)α gene activation by IL-1β is dependent on an upstream kinase pathway, enzymatic activation and downstream 15-lipoxygenase activity: a positive feedback loop JN Walters, JS Bickford, DE Beachy, KJ Newsom, JD Herlihy, MV Peck, X Qiu, HS Nick	Cellular Signalling	2011
Regulation of γ-globin gene expression involves signaling through the p38 MAPK/CREB1 pathway V Ramakrishnan, BS Pace	Blood Cells, Molecules, and Diseases	2011
Fungal Allergen β-Glucans Trigger p38 Mitogen-Activated Protein Kinase–Mediated IL-6 Translation in Lung Epithelial Cells WA Neveu, E Bernardo, JL Allard, V Nagaleekar, MJ Wargo, RJ Davis, Y Iwakura, LA Whittaker, M Rincon	American journal of respiratory cell and molecular biology	2011
AMPK Regulates Metabolic Actions of Glucocorticoids by Phosphorylating the Glucocorticoid Receptor through p38 MAPK N Nader, SS Ng, GI Lambrou, P Pervanidou, Y Wang, GP Chrousos, T Kino	Molecular Endocrinology	2010
Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring transforming growth factor beta-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis TF Li, L Gao, TJ Sheu, ER Sampson, LM Flick, YT Konttinen, D Chen, EM Schwarz, MJ Zuscik, JH Jonason, RJ O'Keefe	Arthritis & Rheumatism	2010
Advanced glycation end products inhibit Na+ K+ ATPase in proximal tubule epithelial cells: Role of cytosolic phospholipase A2α and phosphatidylinositol 4-phosphate 5-kinase γ MA Gallicchio, LA Bach	Biochimica et Biophysica Acta (BBA) - Molecular Cell Research	2010
A Role for ATF2 in Regulating MITF and Melanoma Development M Shah, A Bhoumik, V Goel, A Dewing, W Breitwieser, H Kluger, S Krajewski, M Krajewska, J DeHart, E Lau, DM Kallenberg, H Jeong, A Eroshkin, DC Bennett, L Chin, M Bosenberg, N Jones, ZA Ronai, JM Ford	PLoS genetics	2010
Two Genes on A/J Chromosome 18 Are Associated with Susceptibility to Staphylococcus aureus Infection by Combined Microarray and QTL Analyses SH Ahn, H Deshmukh, N Johnson, LG Cowell, TH Rude, WK Scott, CL Nelson, AK Zaas, DA Marchuk, S Keum, S Lamlertthon, BK Sharma-Kuinkel, GD Sempowski, VG Fowler, MR Wessels	PLoS pathogens	2010
Thyroid cancer: current molecular perspectives F Giusti, A Falchetti, F Franceschelli, F Marini, A Tanini, ML Brandi	Journal of Oncology	2010
Monocyte 15-lipoxygenase gene expression requires ERK1/2 MAPK activity A Bhattacharjee, A Mulya, S Pal, B Roy, GM Feldman, MK Cathcart	Journal of immunology (Baltimore, Md. : 1950)	2010
Effect of gonadectomy on the metabolism of arachidonic acid in isolated kidney of a rat model of metabolic syndrome I Pérez-Torres, ME Hafidi, N Pavón, O Infante, MC Avila-Casado, G Baños	Metabolism	2010
Cyclic AMP stimulates Mrp2 translocation by activating p38α MAPK in hepatic cells CM Schonhoff, CR Webster, MS Anwer	AJP Gastrointestinal and Liver Physiology	2010
Myocardial adenosine A1-receptor-mediated adenoprotection involves phospholipase C, PKC-ε, and p38 MAPK, but not HSP27 RA Fenton, LG Shea, C Doddi, JG Dobson	American journal of physiology. Heart and circulatory physiology	2010
Silencing of the JNK pathway maintains progesterone receptor activity in decidualizing human endometrial stromal cells exposed to oxidative stress signals B Leitao, MC Jones, L Fusi, J Higham, Y Lee, M Takano, T Goto, M Christian, EW Lam, JJ Brosens	The FASEB Journal	2010
Modulation of protein kinase signaling cascades by palytoxin EV Wattenberg	Toxicon : official journal of the International Society on Toxinology	2010
The p38 MAPK Regulates IL-24 Expression by Stabilization of the 3′ UTR of IL-24 mRNA K Otkjaer, H Holtmann, TW Kragstrup, SR Paludan, C Johansen, M Gaestel, K Kragballe, L Iversen	PloS one	2010
5-HT1A Receptor-Regulated Signal Transduction Pathways in Brain AM Polter, X Li	Cellular Signalling	2010
Verotoxin-1 Treatment or Manipulation of its Receptor Globotriaosylceramide (Gb3) for Reversal of Multidrug Resistance to Cancer Chemotherapy P Behnam-Motlagh, A Tyler, K Grankvist, A Johansson	Toxins	2010
Role of protein kinase C in the TBT-induced inhibition of lytic function and MAPK activation in human natural killer cells AB Abraha, K Rana, MM Whalen	Archives of Environmental Contamination and Toxicology	2010
Vitamins & Hormones KJ Hare, FK Knop	Vitamins & Hormones	2010
The p38 mitogen-activated protein kinase pathway--a potential target for intervention in infarction, hypertrophy, and heart failure MS Marber, B Rose, Y Wang	Journal of Molecular and Cellular Cardiology	2010
Dibutyltin activates MAP kinases in human natural killer cells, in vitro SO Odman-Ghazi, A Abraha, ET Isom, MM Whalen	Cell Biology and Toxicology	2010
T Cell LFA-1 Engagement Induces HuR-Dependent Cytokine mRNA Stabilization through a Vav-1, Rac1/2, p38MAPK and MKK3 Signaling Cascade VS Ramgolam, SD DeGregorio, GK Rao, M Collinge, SS Subaran, S Markovic-Plese, R Pardi, JR Bender, D Unutmaz	PloS one	2010
Gap junctions in the control of vascular function XF Figueroa, BR Duling	Antioxidants & Redox Signaling	2009
Dendritic cells for active anti-cancer immunotherapy: targeting activation pathways through genetic modification K Breckpot, D Escors	Endocrine, metabolic & immune disorders drug targets	2009
Targeting Signal Transduction Pathways to Eliminate Chemotherapeutic Drug Resistance and Cancer Stem Cells JA McCubrey, SL Abrams, K Stadelman, WH Chappell, M Lahair, RA Ferland, LS Steelman	Advances in Enzyme Regulation	2009
Brx Mediates the Response of Lymphocytes to Osmotic Stress Through the Activation of NFAT5 T Kino, H Takatori, I Manoli, Y Wang, A Tiulpakov, MR Blackman, YA Su, GP Chrousos, AH DeCherney, JH Segars	Science signaling	2009
p38-γ–dependent gene silencing restricts entry into the myogenic differentiation program MA Gillespie, FL Grand, A Scimè, S Kuang, J Maltzahn, V Seale, A Cuenda, JA Ranish, MA Rudnicki	The Journal of Cell Biology	2009
Extracellular signal regulated kinase 5 mediates signals triggered by the novel tumor promoter palytoxin AT Charlson, NA Zeliadt, EV Wattenberg	Toxicology and Applied Pharmacology	2009
MEK4 Function, Genistein Treatment, and Invasion of Human Prostate Cancer Cells L Xu, Y Ding, WJ Catalona, XJ Yang, WF Anderson, B Jovanovic, K Wellman, J Killmer, X Huang, KA Scheidt, RB Montgomery, RC Bergan	JNCI Journal of the National Cancer Institute	2009
P38 mitogen activated protein kinase expression and regulation by interleukin-4 in human B cell non-Hodgkin lymphomas H Ding, AM Gabali, SD Jenson, MS Lim, KS Elenitoba-Johnson	Journal of Hematopathology	2009
Cisplatin-induced expression of Gb3 enables verotoxin-1 treatment of cisplatin resistance in malignant pleural mesothelioma cells D Johansson, C Andersson, J Moharer, A Johansson, P Behnam-Motlagh	British Journal of Cancer	2009
Genome-wide Identification of Post-translational Modulators of Transcription Factor Activity in Human B-Cells K Wang, M Saito, BC Bisikirska, MJ Alvarez, WK Lim, P Rajbhandari, Q Shen, I Nemenman, K Basso, AA Margolin, U Klein, R Dalla-Favera, A Califano	Nature Biotechnology	2009
PEROXYNITRITE-INDUCED P38 MAPK PROAPOPTOTIC SIGNALING IN ENTEROCYTES YS Guner, CJ Ochoa, J Wang, X Zhang, S Steinhauser, L Stephenson, A Grishin, JS Upperman	Biochemical and Biophysical Research Communications	2009
The Potential of p38 MAPK Inhibitors to Modulate Periodontal Infections KL Kirkwood, C Rossa	Current drug metabolism	2009
Nuclear Localization of p38 MAPK in Response to DNA Damage CD Wood, TM Thornton, G Sabio, RA Davis, M Rincon	International journal of biological sciences	2009
Molecular signaling blockade as a new approach to inhibit leukocyte-endothelial interactions for inflammatory bowel disease treatment F Scaldaferri, C Correale, A Gasbarrini, S Danese	Cell adhesion & migration	2009
p38 MAP kinase-dependent regulation of the expression level and subcellular distribution of heterogeneous nuclear ribonucleoprotein A1 and its involvement in cellular senescence in normal human fibroblasts N Shimada, I Rios, H Moran, B Sayers, K Hubbard	RNA biology	2009
p38 alpha MAPK inhibits JNK activation and collaborates with IkappaB kinase 2 to prevent endotoxin-induced liver failure J Heinrichsdorff, T Luedde, E Perdiguero, AR Nebreda, M Pasparakis	EMBO reports	2008
Protein kinase C beta inhibitors: a new therapeutic target for diabetic nephropathy and vascular complications S Budhiraja, J Singh	Fundamental & Clinical Pharmacology	2008
High-Glucose-Induced Prostaglandin E2and Peroxisome Proliferator-Activated Receptor δ Promote Mouse Embryonic Stem Cell Proliferation YH Kim, HJ Han	Stem Cells	2008
Protein kinase C-β inhibition for diabetic kidney disease KR Tuttle	Diabetes Research and Clinical Practice	2008
Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1 A Blagoveshchenskaya, FY Cheong, HM Rohde, G Glover, A Knödler, T Nicolson, G Boehmelt, P Mayinger	The Journal of Cell Biology	2008
Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways G Tang, Z Yue, Z Talloczy, T Hagemann, W Cho, A Messing, DL Sulzer, JE Goldman	Human Molecular Genetics	2008
ALTERATION OF AKT ACTIVITY INCREASES CHEMOTHERAPEUTIC DRUG AND HORMONAL RESISTANCE IN BREAST CANCER YET CONFERS AN ACHILLES HEEL BY SENSITIZATION TO TARGETED THERAPY JA McCubrey, ML Sokolosky, BD Lehmann, JR Taylor, PM Navolanic, WH Chappell, SL Abrams, KM Stadelman, EW Wong, N Misaghian, S Horn, J Bäsecke, M Libra, F Stivala, G Ligresti, A Tafuri, M Milella, M Zarzycki, A Dzugaj, F Chiarini, C Evangelisti, AM Martelli, DM Terrian, RA Franklin, LS Steelman	Advances in Enzyme Regulation	2008
Long-term Activation of c-Jun N-terminal Kinase through Receptor Interacting Protein is Associated with DNA Damage-induced Cell Death JH Seok, KA Park, HS Byun, M Won, S Shin, BL Choi, H Lee, YR Kim, JH Hong, J Park, GM Hur	The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology	2008
The type 2C phosphatase Wip1: An oncogenic regulator of tumor suppressor and DNA damage response pathways X Lu, TA Nguyen, SH Moon, Y Darlington, M Sommer, LA Donehower	Cancer metastasis reviews	2008
FR167653 inhibits fibronectin expression and apoptosis in diabetic glomeruli and in high-glucose-stimulated mesangial cells DS Jung, JJ Li, SJ Kwak, SH Lee, J Park, YS Song, TH Yoo, SH Han, JE Lee, DK Kim, SJ Moon, YS Kim, DS Han, SW Kang	American journal of physiology. Renal physiology	2008
ATF2 on the double - activating transcription factor and DNA damage response protein A Bhoumik, P Lopez-Bergami, Z Ronai	Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society	2007
Distinctive Epidermal Growth Factor Receptor/Extracellular Regulated Kinase-Independent and -Dependent Signaling Pathways in the Induction of Airway Mucin 5B and Mucin 5AC Expression by Phorbol 12-Myristate 13-Acetate DY Wu, R Wu, SP Reddy, YC Lee, MM Chang	The American Journal of Pathology	2007
Protein kinase C ?? inhibition: the promise for treatment of diabetic nephropathy PW Anderson, JB McGill, KR Tuttle	Current Opinion in Nephrology and Hypertension	2007
Role of protein kinase C inhibition in the development of diabetic microvascular complications V Skljarevski, SJ Ferdinand, KA Kles	Expert Review of Endocrinology & Metabolism	2007
The role of protein kinase C activation in diabetic nephropathy H Noh, GL King	Kidney International	2007
Distinct cardiodynamic and molecular characteristics during early and late stages of sepsis-induced myocardial dysfunction M Chopra, AC Sharma	Life Sciences	2007
Effects of long-term elevated glucose on collagen formation by mesangial cells MH Baccora, P Cortes, C Hassett, DW Taube, J Yee	Kidney International	2007
Targeting the RAF/MEK/ERK, PI3K/AKT and P53 pathways in hematopoietic drug resistance JA McCubrey, LS Steelman, RA Franklin, SL Abrams, WH Chappell, EW Wong, BD Lehmann, DM Terrian, J Basecke, F Stivala, M Libra, C Evangelisti, AM Martelli	Advances in Enzyme Regulation	2007
RAGE Expression in Rhabdomyosarcoma Cells Results in Myogenic Differentiation and Reduced Proliferation, Migration, Invasiveness, and Tumor Growth F Riuzzi, G Sorci, R Donato	The American Journal of Pathology	2007
Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells W Breitwieser, S Lyons, AM Flenniken, G Ashton, G Bruder, M Willington, G Lacaud, V Kouskoff, N Jones	Genes & development	2007
Quantitative Time-Resolved Phosphoproteomic Analysis of Mast Cell Signaling L Cao, K Yu, C Banh, V Nguyen, A Ritz, BJ Raphael, Y Kawakami, T Kawakami, AR Salomon	Journal of immunology (Baltimore, Md. : 1950)	2007
Vitamin E down-modulates mitogen-activated protein kinases, nuclear factor-kappaB and inflammatory responses in lung epithelial cells B Ekstrand-Hammarström, C Osterlund, B Lilliehöök, A Bucht	Clinical & Experimental Immunology	2007
Human Biliverdin Reductase, a Previously Unknown Activator of Protein Kinase C βII MD Maines, T Miralem, N Lerner-Marmarosh, J Shen, PE Gibbs	The Journal of biological chemistry	2007
Regulation of TNF-α-activated PKC-ζ signaling by the human biliverdin reductase: identification of activating and inhibitory domains of the reductase N Lerner-Marmarosh, T Miralem, PE Gibbs, MD Maines	The FASEB Journal	2007
Mitogen-activated protein kinase kinase 3 is a pivotal pathway regulating p38 activation in inflammatory arthritis T Inoue, DL Boyle, M Corr, D Hammaker, RJ Davis, RA Flavell, GS Firestein	Proceedings of the National Academy of Sciences	2006
The p38 mitogen-activated protein kinase signaling cascade in CD4 T cells F Dodeller, H Schulze-Koops	Arthritis Research & Therapy	2006
A comprehensive map of the toll-like receptor signaling network K Oda, H Kitano	Molecular Systems Biology	2006
Effects of YM218, a nonpeptide vasopressin V1A receptor-selective antagonist, on vasopressin-induced growth responses in human mesangial cells A Tahara, J Tsukada, Y Tomura, K Momose, T Suzuki, T Yatsu, M Shibasaki	European Journal of Pharmacology	2006
CD95-induced osteoarthritic chondrocyte apoptosis and necrosis: dependency on p38 mitogen-activated protein kinase L Wei, X Sun, Z Wang, Q Chen	Arthritis Research & Therapy	2006
Thioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf mice CC Hsieh, J Papaconstantinou	The FASEB Journal	2006
Palytoxin: exploiting a novel skin tumor promoter to explore signal transduction and carcinogenesis EV Wattenberg	American journal of physiology. Cell physiology	2006
Insufficient Expression of Cyclooxygenase-2 Protein Is Associated With Retarded Degradation of Aggregated Protein in Diabetic Glomeruli Y Hirasawa, A Muramatsu, Y Suzuki, T Nagamatsu	Journal of Pharmacological Sciences	2006
Disposition of [ 14 C]Ruboxistaurin in Humans JL Burkey, KM Campanale, R Barbuch, D O'Bannon, J Rash, C Benson, D Small	Drug Metabolism and Disposition	2006
Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope JL Perfettini, M Castedo, R Nardacci, F Ciccosanti, P Boya, T Roumier, N Larochette, M Piacentini, G Kroemer	Journal of Experimental Medicine	2005
The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina JP SanGiovanni, EY Chew	Progress in Retinal and Eye Research	2005
Loss of mitogen-activated protein kinase kinase kinase 4 (MEKK4) results in enhanced apoptosis and defective neural tube development H Chi, MR Sarkisian, P Rakic, RA Flavell	Proceedings of the National Academy of Sciences	2005
A comprehensive pathway map of epidermal growth factor receptor signaling K Oda, Y Matsuoka, A Funahashi, H Kitano	Molecular Systems Biology	2005
Artocarpol A stimulation of superoxide anion generation in neutrophils involved the activation of PLC, PKC and p38 mitogen-activated PK signaling pathways YH Kuan, RH Lin, LT Tsao, CN Lin, JP Wang	British Journal of Pharmacology	2005
Parameters for measurement of oxidative stress in diabetes mellitus: applicability of enzyme-linked immunosorbent assay for clinical evaluation Eisei Noiri, Hirokazu Tsukahara	Journal of Investigative Medicine	2005
MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock Q Zhao, X Wang, LD Nelin, Y Yao, R Matta, ME Manson, RS Baliga, X Meng, CV Smith, JA Bauer, CH Chang, Y Liu	Journal of Experimental Medicine	2005
Activation of Phosphoinositide 3-kinase in Response to High Glucose Leads to Regulation of Reactive Oxygen Species-Related Nuclear Factor-κB Activation and Cyclooxygenase-2 Expression in Mesangial Cells ML Sheu, FM Ho, KF Chao, ML Kuo, SH Liu	Molecular pharmacology	2004
The endothelium in health and disease: A discussion of the contribution of non-nitric oxide endothelium-derived vasoactive mediators to vascular homeostasis in normal vessels and in type II diabetes CR Triggle, H Ding, TJ Anderson, M Pannirselvam	Molecular and Cellular Biochemistry	2004
High expression of PKC-MAPK pathway mRNAs correlates with glomerular lesions in human diabetic nephropathy M Toyoda, D Suzuki, M Honma, G Uehara, T Sakai, T Umezono, H Sakai	Kidney International	2004
PPARgamma ligands attenuate mesangial contractile dysfunction in high glucose M Ueta, M Wakisaka, T Ago, T Kitazono, U Nakamura, M Yoshinari, M Iwase, M Iida	Kidney International	2004
Expression and Activation of Mitogen-Activated Protein Kinase Kinases-3 and -6 in Rheumatoid Arthritis M Chabaud-Riou, GS Firestein	The American Journal of Pathology	2004
l-Carnitine May Attenuate Free Fatty Acid-Induced Endothelial Dysfunction SS Shankar, B Mirzamohammadi, JP Walsh, HO Steinberg	Annals of the New York Academy of Sciences	2004
Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase DH Kim, NT Liberati, T Mizuno, H Inoue, N Hisamoto, K Matsumoto, FM Ausubel	Proceedings of the National Academy of Sciences	2004
Activation of Erk and JNK MAPK pathways by acute swim stress in rat brain regions C Shen, Y Tsimberg, C Salvadore, E Meller	BMC neuroscience	2004
Reduced IP receptors in STZ-induced diabetic rat kidneys and high-glucose-treated mesangial cells R Nasrallah, RL Hébert	American journal of physiology. Renal physiology	2004
The p38 mitogen-activated protein kinase regulates interleukin-1beta-induced IL-8 expression via an effect on the IL-8 promoter in intestinal epithelial cells K Parhar, A Ray, U Steinbrecher, C Nelson, B Salh	Immunology	2003
International Textbook of Diabetes Mellitus RA DeFronzo, L Mandarino, E Ferrannini	International Textbook of Diabetes Mellitus	2003
A novel potential therapy for diabetic nephropathy and vascular complications: protein kinase C β inhibition KR Tuttle, PW Anderson	American Journal of Kidney Diseases	2003
High glucose activates the p38 MAPK pathway in cultured human peritoneal mesothelial cells ZG Xu, KS Kim, HC Park, KH Choi, HY Lee, DS Han, SW Kang	Kidney International	2003
Integrated transcriptome analysis of the cellular mechanisms associated with Ha-ras-dependent malignant transformation of the human breast epithelial MCF7 cell line F Gadal, C Bozic, C Pillot-Brochet, S Malinge, S Wagner, AL Cam, L Buffat, M Crepin, F Iris	Nucleic Acids Research	2003
Exploiting features of adenovirus replication to support mammalian kinase production M Cotten, K Stegmueller, J Eickhoff, M Hanke, K Herzberger, T Herget, A Choidas, H Daub, K Godl	Nucleic Acids Research	2003
CCR5 Expression Influences the Progression of Human Breast Cancer in a p53-dependent Manner S Mañes, E Mira, R Colomer, S Montero, LM Real, C Gómez-Moutón, S Jiménez-Baranda, A Garzón, RA Lacalle, K Harshman, A Ruíz, C Martínez-A	Journal of Experimental Medicine	2003
A critical role of neural-specific JNK3 for ischemic apoptosis CY Kuan, AJ Whitmarsh, DD Yang, G Liao, AJ Schloemer, C Dong, J Bao, KJ Banasiak, GG Haddad, RA Flavell, RJ Davis, P Rakic	Proceedings of the National Academy of Sciences	2003
Mechanism of p38 MAP kinase activation in vivo D Brancho, N Tanaka, A Jaeschke, JJ Ventura, N Kelkar, Y Tanaka, M Kyuuma, T Takeshita, RA Flavell, RJ Davis	Genes & development	2003
The osmoregulatory and the amino acid-regulated responses of system A are mediated by different signal transduction pathways M López-Fontanals, S Rodríguez-Mulero, FJ Casado, B Dérijard, M Pastor-Anglada	The Journal of General Physiology	2003
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis K Lei, RJ Davis	Proceedings of the National Academy of Sciences	2003
The death domain kinase RIP1 is essential for tumor necrosis factor alpha signaling to p38 mitogen-activated protein kinase TH Lee, Q Huang, S Oikemus, J Shank, JJ Ventura, N Cusson, RR Vaillancourt, B Su, RJ Davis, MA Kelliher	Molecular and cellular biology	2003
p38alpha isoform Mxi2 binds to extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase and regulates its nuclear activity by sustaining its phosphorylation levels V Sanz-Moreno, B Casar, P Crespo	Molecular and cellular biology	2003
Identification of Cdc37 as a novel regulator of the stress-responsive mitogen-activated protein kinase H Tatebe, K Shiozaki	Molecular and cellular biology	2003
p38α Isoform Mxi2 Binds to Extracellular Signal-Regulated Kinase 1 and 2 Mitogen-Activated Protein Kinase and Regulates Its Nuclear Activity by Sustaining Its Phosphorylation Levels V Sanz-Moreno, B Casar, P Crespo	Molecular and cellular biology	2003
Overview of Glucose Signaling in Mesangial Cells in Diabetic Nephropathy M Haneda, D Koya, M Isono, R Kikkawa	Journal of the American Society of Nephrology : JASN	2003
p38 MAP kinase negatively regulates endothelial cell survival, proliferation, and differentiation in FGF-2–stimulated angiogenesis T Matsumoto, I Turesson, M Book, P Gerwins, L Claesson-Welsh	The Journal of Cell Biology	2002
Prevention of diabetic nephropathy in rats by prostaglandin E receptor EP1-selective antagonist H Makino, I Tanaka, M Mukoyama, A Sugawara, K Mori, S Muro, T Suganami, K Yahata, R Ishibashi, S Ohuchida, T Maruyama, S Narumiya, K Nakao	Journal of the American Society of Nephrology : JASN	2002
High glucose down-regulates angiotensin II binding via the PKC-MAPK-cPLA2 signal cascade in renal proximal tubule cells SH Park, CH Woo, JH Kim, JH Lee, IS Yang, KM Park, HJ Han	Kidney International	2002
ANTIOXIDANTS MODULATE ADENOSINE METABOLISM IN RAT MESANGIAL CELLS CULTURED UNDER HIGH GLUCOSE CONDITIONS G Kocic, V Djordjevic, P Vlahovic, R Kocic, D Pavlovic, T Jevtovic	Renal Failure	2002
Stimulation of β3-adrenoceptors causes phosphorylation of p38 mitogen-activated protein kinase via a stimulatory G protein-dependent pathway in 3T3-L1 adipocytes K Mizuno, Y Kanda, Y Kuroki, M Nishio, Y Watanabe	British Journal of Pharmacology	2002
Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation L Ulloa, M Ochani, H Yang, M Tanovic, D Halperin, R Yang, CJ Czura, MP Fink, KJ Tracey	Proceedings of the National Academy of Sciences	2002
The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase K Lei, A Nimnual, WX Zong, NJ Kennedy, RA Flavell, CB Thompson, D Bar-Sagi, RJ Davis	Molecular and cellular biology	2002
Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence W Wang, JX Chen, R Liao, Q Deng, JJ Zhou, S Huang, P Sun	Molecular and cellular biology	2002
IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition MG Sanna, JS Correia, O Ducrey, J Lee, K Nomoto, N Schrantz, QL Deveraux, RJ Ulevitch	Molecular and cellular biology	2002
Cellular N-Ras promotes cell survival by downregulation of Jun N-terminal protein kinase and p38 JC Wolfman, T Palmby, CJ Der, A Wolfman	Molecular and cellular biology	2002
Epstein-Barr virus latent membrane protein 2A regulates c-Jun protein through extracellular signal-regulated kinase SY Chen, J Lu, YC Shih, CH Tsai	Journal of virology	2002
The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function X Li, X Bu, B Lu, H Avraham, RA Flavell, B Lim	Molecular and cellular biology	2002
The Bax Subfamily of Bcl2-Related Proteins Is Essential for Apoptotic Signal Transduction by c-Jun NH2-Terminal Kinase K Lei, A Nimnual, WX Zong, NJ Kennedy, RA Flavell, CB Thompson, D Bar-Sagi, RJ Davis	Molecular and cellular biology	2002
Sequential Activation of the MEK-Extracellular Signal-Regulated Kinase and MKK3/6-p38 Mitogen-Activated Protein Kinase Pathways Mediates Oncogenic ras-Induced Premature Senescence† W Wang, JX Chen, R Liao, Q Deng, JJ Zhou, S Huang, P Sun	Molecular and cellular biology	2002
Requirement of the p38 mitogen-activated protein kinase signalling pathway for the induction of the 78 kDa glucose-regulated protein/immunoglobulin heavy-chain binding protein by azetidine stress: activating transcription factor 6 as a target for stress-induced phosphorylation S Luo, AS Lee	Biochemical Journal	2002
Anti-inflammatory effect of cholecystokinin and its signal transduction mechanism in endotoxic shock rat Ai-Hong Meng, Yi-Ling Ling, Xiao-Peng Zhang, Jun-Lan Zhang	World journal of gastroenterology : WJG	2002
Interaction of MAPK and 12-lipoxygenase pathways in growth and matrix protein expression in mesangial cells MA Reddy, SG Adler, YS Kim, L Lanting, J Rossi, SW Kang, JL Nadler, A Shahed, R Natarajan	American journal of physiology. Renal physiology	2002
Mesangial cell filamentous actin disassembly and hypocontractility in high glucose are mediated by PKC-ζ JA Dlugosz, S Munk, E Ispanovic, HJ Goldberg, CI Whiteside	American journal of physiology. Renal physiology	2002
ERK and p38 MAP kinase are involved in arachidonic acid release induced by H 2 O 2 and PDGF in mesangial cells M Hayama, R Inoue, S Akiba, T Sato	American journal of physiology. Renal physiology	2002
Nonsteroidal anti‐inflammatory drugs prevent early diabetic retinopathy via TNF‐α suppression AM Joussen, V Poulaki, N Mitsiades, B Kirchhof, K Koizumi, S Döhmen, AP Adamis	The FASEB Journal	2002
Murine Lyme Arthritis Development Mediated by p38 Mitogen-Activated Protein Kinase Activity J Anguita, SW Barthold, R Persinski, MN Hedrick, CA Huy, RJ Davis, RA Flavell, E Fikrig	Journal of immunology (Baltimore, Md. : 1950)	2002
Renal cyclooxygenase-2 in experimental diabetes. immunohistochemical and functional correlation Radko Komers, Jessie N. Lindsley, Terry T. Oyama, William E. Schutzer, John F. Reed, Scott L. Mader, Sharon Anderson	Journal of Clinical Investigation	2001
Protein kinase C and the development of diabetic vascular complications KJ Way, N Katai, GL King	Diabetic Medicine	2001
p38 MAPK and MAPK kinase 3/6 mRNA and activities are increased in early diabetic glomeruli SW Kang, SG Adler, J Lapage, R Natarajan	Kidney International	2001
Protein kinase C inhibitors in the treatment and prevention of diabetic complications A Gabriele, GL King	Current Opinion in Endocrinology & Diabetes	2001
The role of oxidative stress in the onset and progression of diabetes and its complications: asummary of a Congress Series sponsored byUNESCO-MCBN, the American Diabetes Association and the German Diabetes Society P R�sen, PP Nawroth, G King, W M�ller, HJ Tritschler, L Packer	Diabetes/Metabolism Research and Reviews	2001
12-Lipoxygenase is increased in glucose-stimulated mesangial cells and in experimental diabetic nephropathy SW Kang, SG Adler, CC Nast, J Lapage, JL Gu, JL Nadler, R Natarajan	Kidney International	2001
Inhibition of p38 MAP kinase during cellular activation results in IFN-gamma-dependent augmentation of IL-12 production by human monocytes/macrophages JB Marriott, IA Clarke, AG Dalgleish	Clinical & Experimental Immunology	2001
Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology D Kontoyiannis, A Kotlyarov, E Carballo, L Alexopoulou, PJ Blackshear, M Gaestel, R Davis, R Flavell, G Kollias	The EMBO Journal	2001
IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: requirement for Runx-2 and activation by p38 MAPK and JNK pathways JA Mengshol, MP Vincenti, CE Brinckerhoff	Nucleic Acids Research	2001
p38 mitogen-activated kinase is a bidirectional regulator of human fibroblast collagenase-1 induction by three-dimensional collagen lattices J Xu, RA Clark, WC Parks	Biochemical Journal	2001
TGFβ and PTHrP Control Chondrocyte Proliferation by Activating Cyclin D1 Expression F Beier, Z Ali, D Mok, AC Taylor, T Leask, C Albanese, RG Pestell, P LuValle	Molecular biology of the cell	2001
Advanced glycosylation end products stimulate collagen mRNA synthesis in mesangial cells mediated by protein kinase C and transforming growth factor–beta YS Kim, BC Kim, CY Song, HK Hong, KC Moon, HS Lee	Journal of Laboratory and Clinical Medicine	2001
The epithelial Na(+) channel (ENaC) is related to the hypertonicity-induced Na(+) conductance in rat hepatocytes L New, Y Jiang, M Zhao, K Liu, W Zhu, LJ Flood, Y Kato, GC Parry, J Han	FEBS Letters	2001
The epithelial Na(+) channel (ENaC) is related to the hypertonicity-induced Na(+) conductance in rat hepatocytes L New, Y Jiang, M Zhao, K Liu, W Zhu, LJ Flood, Y Kato, GC Parry, J Han	FEBS Letters	2001
SEK-1 MAPKK mediates Ca2+ signaling to determine neuronal asymmetric development in Caenorhabditis elegans M Tanaka-Hino, A Sagasti, N Hisamoto, M Kawasaki, S Nakano, J Ninomiya-Tsuji, CI Bargmann, K Matsumoto	EMBO reports	2001
jkk-1 and mek-1 regulate body movement coordination and response to heavy metals through jnk-1 in Caenorhabditis elegans A Villanueva, J Lozano, A Morales, X Lin, X Deng, MO Hengartner, RN Kolesnick	The EMBO Journal	2001
MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines C Tournier, C Dong, TK Turner, SN Jones, RA Flavell, RJ Davis	Genes & development	2001
TRAF6 is a critical mediator of signal transduction by the viral oncogene latent membrane protein 1 U Schultheiss, S Püschner, E Kremmer, TW Mak, H Engelmann, W Hammerschmidt, A Kieser	The EMBO Journal	2001
Regulation of alternative pre-mRNA splicing by the ERK MAP-kinase pathway S Weg-Remers, H Ponta, P Herrlich, H König	The EMBO Journal	2001
FRET-based detection of different conformations of MK2 A Neininger, H Thielemann, M Gaestel	EMBO reports	2001
Adenovirus-activated PKA and p38/MAPK pathways boost microtubule-mediated nuclear targeting of virus M Suomalainen, MY Nakano, K Boucke, S Keller, UF Greber	The EMBO Journal	2001
Regulation of gene expression by the small GTPase Rho through the ERK6 (p38 gamma) MAP kinase pathway MJ Marinissen, M Chiariello, JS Gutkind	Genes & development	2001
The stress kinase mitogen-activated protein kinase kinase (MKK)7 is a negative regulator of antigen receptor and growth factor receptor-induced proliferation in hematopoietic cells T Sasaki, T Wada, H Kishimoto, J Irie-Sasaki, G Matsumoto, T Goto, Z Yao, A Wakeham, TW Mak, A Suzuki, SK Cho, JC Zuniga-Pflucker, AJ Oliveira-dos-Santos, T Katada, H Nishina, JM Penninger	Journal of Experimental Medicine	2001
Parallel and independent regulation of interleukin-3 mRNA turnover by phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase XF Ming, G Stoecklin, M Lu, R Looser, C Moroni	Molecular and cellular biology	2001
Involvement of p38 in apoptosis-associated membrane blebbing and nuclear condensation RG Deschesnes, J Huot, K Valerie, J Landry	Molecular biology of the cell	2001
p38-mediated regulation of an Fas-associated death domain protein-independent pathway leading to caspase-8 activation during TGFbeta-induced apoptosis in human Burkitt lymphoma B cells BL41 N Schrantz, MF Bourgeade, S Mouhamad, G Leca, S Sharma, A Vazquez	Molecular biology of the cell	2001
Expression of hsp16 in response to nucleotide depletion is regulated via the spc1 MAPK pathway in Schizosaccharomyces pombe L Taricani, HE Feilotter, C Weaver, PG Young	Nucleic Acids Research	2001
High glucose and advanced glycation end products induce phospholipid hydrolysis and phospholipid enzyme inhibition in bovine retinal pericytes G Assero, G Lupo, CD Anfuso, N Ragusa, M Alberghina	Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids	2001
Modulating sensitivity to drug-induced apoptosis: the future for chemotherapy? G Makin, C Dive	Breast Cancer Research	2001
Simultaneous measurement of ERK, p38, and JNK MAP kinase cascades in vascular smooth muscle cells D Chevalier, E Thorin, B G Allen	Journal of Pharmacological and Toxicological Methods	2001
Differential regulation of mitogen-activated protein kinases ERK1/2 and ERK5 by neurotrophins, neuronal activity, and cAMP in neurons J E Cavanaugh, J Ham, M Hetman, S Poser, C Yan, Z Xia	The Journal of neuroscience : the official journal of the Society for Neuroscience	2001
Small heat shock protein alteration provides a mechanism to reduce mesangial cell contractility in diabetes and oxidative stress ME Dunlop, EE Muggli	Kidney International	2000
Nonopsonic binding of type III Group B Streptococci to human neutrophils induces interleukin-8 release mediated by the p38 mitogen-activated protein kinase pathway EA Albanyan, JG Vallejo, CW Smith, MS Edwards	Infection and immunity	2000
Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells M Allen, L Svensson, M Roach, J Hambor, J McNeish, CA Gabel	Journal of Experimental Medicine	2000
Thrombin is a novel regulator of hexokinase activity in mesangial cells RB Robey, BJ Raval, J Ma, AV Santos	Kidney International	2000
Modifications in the TXA2and PGI2plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit B Lasserre, C Navarro-Delmasure, AP Chanh, J Catala, E Hollande	Prostaglandins, Leukotrienes and Essential Fatty Acids	2000
Regulation and function of p38 protein kinase in isolated canine gastric parietal cells Y Marunaka, H Tohda, N Hagiwara, H O'Brodovich	AJP Gastrointestinal and Liver Physiology	2000
Investigation into the involvement of phospholipases A(2) and MAP kinases in modulation of AA release and cell growth in A549 cells QG Choudhury, DT McKay, RJ Flower, JD Croxtall	British Journal of Pharmacology	2000
The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death M Kurokawa, K Mitani, T Yamagata, T Takahashi, K Izutsu, S Ogawa, T Moriguchi, E Nishida, Y Yazaki, H Hirai	The EMBO Journal	2000
Molecular determinants that mediate selective activation of p38 MAP kinase isoforms H Enslen, DM Brancho, RJ Davis	The EMBO Journal	2000
The p38 MAP kinase inhibitor SB203580 enhances nuclear factor-kappa B transcriptional activity by a non-specific effect upon the ERK pathway KU Birkenkamp, LM Tuyt, C Lummen, AT Wierenga, W Kruijer, E Vellenga	British Journal of Pharmacology	2000
The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin KC Goh, MJ deVeer, BR Williams	The EMBO Journal	2000
A method to predict residues conferring functional differences between related proteins: application to MAP kinase pathways DR Caffrey, LA O'Neill, DC Shields	Protein science : a publication of the Protein Society	2000
Extracellular nucleotides activate the p38-stress-activated protein kinase cascade in glomerular mesangial cells A Huwiler, M Wartmann, H Bosch, J Pfeilschifter	British Journal of Pharmacology	2000
Effect of AT1 angiotensin receptor antagonist on lipid peroxidation and antioxidative defense in diabetic kidney K Kędziora-Kornatowska, M Luciak, J Błaszczyk, W Pawlak, J Kędziora	Pathophysiology	2000
Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor G Vitale, L Bernardi, G Napolitani, M Mock, C Montecucco	Biochemical Journal	2000
Apoptotic signalling cascade in photosensitized human epidermal carcinoma A431 cells: involvement of singlet oxygen, c-Jun N-terminal kinase, caspase-3 and p21-activated kinase 2 WH Chan, JS Yu, SD Yang	Biochemical Journal	2000
Asymmetric p38 activation in zebrafish: its possible role in symmetric and synchronous cleavage R Fujii, S Yamashita, M Hibi, T Hirano	The Journal of Cell Biology	2000
Marathon running transiently increases c-Jun NH2-terminal kinase and p38 activities in human skeletal muscle MD Boppart, S Asp, JF Wojtaszewski, RA Fielding, T Mohr, LJ Goodyear	The Journal of Physiology	2000
p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons S Ghatan, S Larner, Y Kinoshita, M Hetman, L Patel, Z Xia, RJ Youle, RS Morrison	The Journal of Cell Biology	2000
Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest X Wang, CH McGowan, M Zhao, L He, JS Downey, C Fearns, Y Wang, S Huang, J Han	Molecular and cellular biology	2000
MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration Y Xia, C Makris, B Su, E Li, J Yang, GR Nemerow, M Karin	Proceedings of the National Academy of Sciences	2000
p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps Z Wu, PJ Woodring, KS Bhakta, K Tamura, F Wen, JR Feramisco, M Karin, JY Wang, PL Puri	Molecular and cellular biology	2000
Interleukin-6-induced STAT3 transactivation and Ser727 phosphorylation involves Vav, Rac-1 and the kinase SEK-1/MKK-4 as signal transduction components JJ Schuringa, LJ Jonk, WH Dokter, E Vellenga, W Kruijer	Biochemical Journal	2000
Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation J Cheng, J Yang, Y Xia, M Karin, B Su	Molecular and cellular biology	2000
Activation of the p38 mitogen-activated protein kinase pathway arrests cell cycle progression and differentiation of immature thymocytes in vivo NL Diehl, H Enslen, KA Fortner, C Merritt, N Stetson, C Charland, RA Flavell, RJ Davis, M Rincón	Journal of Experimental Medicine	2000
Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3 N Kelkar, S Gupta, M Dickens, RJ Davis	Molecular and cellular biology	2000
Activation of p38 mitogen-activated protein kinase in vivo selectively induces apoptosis of CD8(+) but not CD4(+) T cells C Merritt, H Enslen, N Diehl, D Conze, RJ Davis, M Rincón	Molecular and cellular biology	2000
Activation of the mitogen-activated protein kinase p38 by human cytomegalovirus infection through two distinct pathways: a novel mechanism for activation of p38 RA Johnson, SM Huong, ES Huang	Journal of virology	2000
Regulation of c-Jun NH(2)-terminal kinase (Jnk) gene expression during T cell activation L Weiss, AJ Whitmarsh, DD Yang, M Rincón, RJ Davis, RA Flavell	Journal of Experimental Medicine	2000
Activation of p38 mitogen-activated protein kinase and c-Jun NH(2)-terminal kinase by double-stranded RNA and encephalomyocarditis virus: involvement of RNase L, protein kinase R, and alternative pathways MS Iordanov, JM Paranjape, A Zhou, J Wong, BR Williams, EF Meurs, RH Silverman, BE Magun	Molecular and cellular biology	2000
Role for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damage K Yoshida, R Weichselbaum, S Kharbanda, D Kufe	Molecular and cellular biology	2000
Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade M Lasa, KR Mahtani, A Finch, G Brewer, J Saklatvala, AR Clark	Molecular and cellular biology	2000
The MKK(3/6)-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulation WH der van Oordt, MT Diaz-Meco, J Lozano, AR Krainer, J Moscat, JF Cáceres	The Journal of Cell Biology	2000
Multistep phosphorelay proteins transmit oxidative stress signals to the fission yeast stress-activated protein kinase AN Nguyen, A Lee, W Place, K Shiozaki	Molecular biology of the cell	2000
Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells PL Puri, Z Wu, P Zhang, LD Wood, KS Bhakta, J Han, JR Feramisco, M Karin, JY Wang	Genes & development	2000
Multiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformation M Chiariello, MJ Marinissen, JS Gutkind	Molecular and cellular biology	2000
c-Myc protein synthesis is initiated from the internal ribosome entry segment during apoptosis M Stoneley, SA Chappell, CL Jopling, M Dickens, M MacFarlane, AE Willis	Molecular and cellular biology	2000
Epstein-Barr virus immediate-early proteins BZLF1 and BRLF1 activate the ATF2 transcription factor by increasing the levels of phosphorylated p38 and c-Jun N-terminal kinases AL Adamson, D Darr, E Holley-Guthrie, RA Johnson, A Mauser, J Swenson, S Kenney	Journal of virology	2000
Asymmetric p38 Activation in Zebrafish R Fujii, S Yamashita, M Hibi, T Hirano	The Journal of Cell Biology	2000
The Mkk3/6-p38–Signaling Cascade Alters the Subcellular Distribution of Hnrnp A1 and Modulates Alternative Splicing Regulation WH der van Oordt, MT Diaz-Meco, J Lozano, AR Krainer, J Moscat, JF Cáceres	The Journal of Cell Biology	2000
Protein kinase C activation and its pharmacological inhibition in vascular disease M Meier, GL King	Vascular medicine (London, England)	2000
Hexosamine regulation of glucose-mediated laminin synthesis in mesangial cells involves protein kinases A and C LP Singh, ED Crook	American journal of physiology. Renal physiology	2000
The Kidney and Hypertension in Diabetes Mellitus CE Mogensen		2000
Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons E T Coffey, V Hongisto, M Dickens, R J Davis, M J Courtney	The Journal of neuroscience : the official journal of the Society for Neuroscience	2000
Cerebral ischemia and seizures induce tyrosine phosphorylation of PYK2 in neurons and microglial cells D Tian, V Litvak, S Lev	The Journal of neuroscience : the official journal of the Society for Neuroscience	2000
Activation of MEK Kinase 1 by the c-Abl Protein Tyrosine Kinase in Response to DNA Damage S Kharbanda, P Pandey, T Yamauchi, S Kumar, M Kaneki, V Kumar, A Bharti, ZM Yuan, L Ghanem, A Rana, R Weichselbaum, G Johnson, D Kufe	Molecular and cellular biology	2000
Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways M Igarashi, H Wakasaki, N Takahara, H Ishii, ZY Jiang, T Yamauchi, K Kuboki, M Meier, CJ Rhodes, GL King	Journal of Clinical Investigation	1999
Selective activation and functional significance of p38α mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils JA Nick, NJ Avdi, SK Young, LA Lehman, PP McDonald, SC Frasch, MA Billstrom, PM Henson, GL Johnson, GS Worthen	Journal of Clinical Investigation	1999
Effect of protein kinase C and phospholipase A2inhibitors on the impaired ability of human diabetic platelets to cause vasodilation HJ Oskarsson, TG Hofmeyer, L Coppey, MA Yorek	British Journal of Pharmacology	1999
Can protein kinase C inhibition and vitamin E prevent the development of diabetic vascular complications? S Bursell	Diabetes Research and Clinical Practice	1999
Renal production of thromboxane and prostaglandins in a rat model of type 2 diabetes M Okumura, M Imanishi, T Yamashita, Y Yamamura, S Kim, H Iwao, S Tanaka, S Fujii	Life Sciences	1999
Differential expression of protein kinase C isoforms in streptozotocin-induced diabetic rats N Kang, G Alexander, JK Park, C Maasch, I Buchwalow, FC Luft, H Haller	Kidney International	1999
Roles of prostaglandin E receptors in mesangial cells under high-glucose conditions R Ishibashi, I Tanaka, M Kotani, S Muro, M Goto, A Sugawara, M Mukoyama, Y Sugimoto, A Ichikawa, S Narumiya, K Nakao	Kidney International	1999
Selective activation and functional significance of p38α mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils JA Nick, NJ Avdi, SK Young, LA Lehman, PP McDonald, SC Frasch, MA Billstrom, PM Henson, GL Johnson, GS Worthen	Journal of Clinical Investigation	1999
The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells F Bost, R McKay, M Bost, O Potapova, NM Dean, D Mercola	Molecular and cellular biology	1999
Role of protein kinase C in cisplatin nephrotoxicity S Ikeda, A Fukuzaki, H Kaneto, S Ishidoya, S Orikasa	International Journal of Urology	1999
Effect of angiotensin convertase inhibitors and AT1 angiotensin receptor antagonists on the development of oxidative stress in the kidney of diabetic rats K Kȩdziora-Kornatowska	Clinica Chimica Acta	1999
Potentiating effects of hyper-osmolality and epidermal growth factor on the release of arachidonic acid in human glomerular mesangial cells SC Sansom, P Mehta, DA Hall	Diabetes Research and Clinical Practice	1999
Role of AT(1) receptors and autonomic nervous system in mediating acute pressor responses to ANG II in anesthetized mice K Hayashi, M Takahashi, K Kimura, W Nishida, H Saga, K Sobue	The American journal of physiology	1999
Activation of the AP-1 transcription factor by inflammatory cytokines of the TNF family AJ Whitmarsh, RJ Davis	Gene expression	1999
Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice HT Lu, DD Yang, M Wysk, E Gatti, I Mellman, RJ Davis, RA Flavell	The EMBO Journal	1999
Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells A Nehmé, R Baskaran, S Nebel, D Fink, SB Howell, JY Wang, RD Christen	British Journal of Cancer	1999
TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway BA Hocevar, TL Brown, PH Howe	The EMBO Journal	1999
c-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation F Cong, SP Goff	Proceedings of the National Academy of Sciences	1999
BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M K Yamamoto, H Ichijo, SJ Korsmeyer	Molecular and cellular biology	1999
Novel membrane-targeted ERK1 and ERK2 chimeras which act as dominant negative, isotype-specific mitogen-activated protein kinase inhibitors of Ras-Raf-mediated transcriptional activation of c-fos in NIH 3T3 cells F Hochholdinger, G Baier, A Nogalo, B Bauer, HH Grunicke, F Uberall	Molecular and cellular biology	1999
JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway M Ito, K Yoshioka, M Akechi, S Yamashita, N Takamatsu, K Sugiyama, M Hibi, Y Nakabeppu, T Shiba, KI Yamamoto	Molecular and cellular biology	1999
The net repressor is regulated by nuclear export in response to anisomycin, UV, and heat shock C Ducret, SM Maira, A Dierich, B Wasylyk	Molecular and cellular biology	1999
TANK potentiates tumor necrosis factor receptor-associated factor-mediated c-Jun N-terminal kinase/stress-activated protein kinase activation through the germinal center kinase pathway AI Chin, J Shu, CS Shi, Z Yao, JH Kehrl, G Cheng	Molecular and cellular biology	1999
Role of mitogen-activated protein kinases in activation-induced apoptosis of T cells L Zhu, X Yu, Y Akatsuka, JA Cooper, C Anasetti	Immunology	1999
Specific inhibition of skeletal alpha-actin gene transcription by applied mechanical forces through integrins and actin AM Lew, M Glogauer, CA Mculloch	Biochemical Journal	1999
Bcl-2 and Bcl-X(L) block thapsigargin-induced nitric oxide generation, c-Jun NH(2)-terminal kinase activity, and apoptosis RK Srivastava, SJ Sollott, L Khan, R Hansford, EG Lakatta, DL Longo	Molecular and cellular biology	1999
The Drosophila p38 MAPK pathway is required during oogenesis for egg asymmetric development M Suzanne, K Irie, B Glise, F Agnès, E Mori, K Matsumoto, S Noselli	Genes & development	1999
Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain V Baud, ZG Liu, B Bennett, N Suzuki, Y Xia, M Karin	Genes & development	1999
Cellular activation triggered by the autosomal dominant polycystic kidney disease gene product PKD2 T Arnould, L Sellin, T Benzing, L Tsiokas, HT Cohen, E Kim, G Walz	Molecular and cellular biology	1999
Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression M Wysk, DD Yang, HT Lu, RA Flavell, RJ Davis	Proceedings of the National Academy of Sciences	1999
Stress- and cell type-dependent regulation of transfected c-Jun N-terminal kinase and mitogen-activated protein kinase kinase isoforms L Butterfield, E Zentrich, A Beekman, LE Heasley	Biochemical Journal	1999
The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases C Tournier, AJ Whitmarsh, J Cavanagh, T Barrett, RJ Davis	Molecular and cellular biology	1999
Interaction of hematopoietic progenitor kinase 1 with adapter proteins Crk and CrkL leads to synergistic activation of c-Jun N-terminal kinase P Ling, Z Yao, CF Meyer, XS Wang, W Oehrl, SM Feller, TH Tan	Molecular and cellular biology	1999
Regulation of the MEF2 family of transcription factors by p38 M Zhao, L New, VV Kravchenko, Y Kato, H Gram, F Padova, EN Olson, RJ Ulevitch, J Han	Molecular and cellular biology	1999
Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways H Holtmann, R Winzen, P Holland, S Eickemeier, E Hoffmann, D Wallach, NL Malinin, JA Cooper, K Resch, M Kracht	Molecular and cellular biology	1999
Activation of cJUN N-terminal kinase by herpes simplex virus type 1 enhances viral replication TI McLean, SL Bachenheimer	Journal of virology	1999
A network of mitogen-activated protein kinases links G protein-coupled receptors to the c-jun promoter: a role for c-Jun NH2-terminal kinase, p38s, and extracellular signal-regulated kinase 5 MJ Marinissen, M Chiariello, M Pallante, JS Gutkind	Molecular and cellular biology	1999
Ubiquitination and degradation of ATF2 are dimerization dependent SY Fuchs, Z Ronai	Molecular and cellular biology	1999
Mitogen-activated protein kinases: specific messages from ubiquitous messengers HJ Schaeffer, MJ Weber	Molecular and cellular biology	1999
Identification of the cyclin D1 gene as a target of activating transcription factor 2 in chondrocytes F Beier, RJ Lee, AC Taylor, RG Pestell, P LuValle	Proceedings of the National Academy of Sciences	1999
Rapid Avr9- and Cf-9 -dependent activation of MAP kinases in tobacco cell cultures and leaves: convergence of resistance gene, elicitor, wound, and salicylate responses T Romeis, P Piedras, S Zhang, DF Klessig, H Hirt, JD Jones	The Plant cell	1999
Integrin α2β1 Mediates Isoform-Specific Activation of p38 and Upregulation of Collagen Gene Transcription by a Mechanism Involving the α2 Cytoplasmic Tail J Ivaska, H Reunanen, J Westermarck, L Koivisto, VM Kähäri, J Heino	The Journal of Cell Biology	1999
Regulation of angiotensin II receptors and PKC isoforms by glucose in rat mesangial cells F Amiri, R Garcia	American journal of physiology. Renal physiology	1999
Roles of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in the signal transduction of basic fibroblast growth factor in endothelial cells during angiogenesis K Tanaka, M Abe, Y Sato	Japanese journal of cancer research : Gann	1999
Regulation of NF-kappaB by the HTLV-1 Tax protein X H Li, R B Gaynor	Gene expression	1999
Effects of Advanced Glycation End Products on Cytosolic Ca 2+ Signaling of Cultured Human Mesangial Cells P Menè, C Pascale, A Teti, SI Bernardini, GA Cinotti, F Pugliese	Journal of the American Society of Nephrology : JASN	1999
Effect of High Glucose on Mesangial Cell Protein Kinase C-δ and -𝛆 is Polyol Pathway-Dependent J Kapor-Drezgic, XI Zhou, T Babazono, JA Dlugosz, T Hohman, C Whiteside	Journal of the American Society of Nephrology : JASN	1999
Hepatitis C Virus Core Protein Enhances NF-κB Signal Pathway Triggering by Lymphotoxin-β Receptor Ligand and Tumor Necrosis Factor Alpha LR You, CM Chen, YH Lee	Journal of virology	1999
Functional Role for Protein Kinase Cβ as a Regulator of Stress-Activated Protein Kinase Activation and Monocytic Differentiation of Myeloid Leukemia Cells M Kaneki, S Kharbanda, P Pandey, K Yoshida, M Takekawa, JR Liou, R Stone, D Kufe	Molecular and cellular biology	1999
Autocrine and paracrine mechanisms in the early stages of diabetic nephropathy G Pugliese, F Pricci, G Romeo, G Leto, L Amadio, C Iacobini, UD Mario	Journal of Endocrinological Investigation	1999
d-α-tocopherol treatment prevents glomerular dysfunctions in diabetic rats through inhibition of protein kinase C-diacylglycerol pathway D Koya, M Haneda, R Kikkawa, GL King	BioFactors	1998
CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation H Häcker, H Mischak, T Miethke, S Liptay, R Schmid, T Sparwasser, K Heeg, GB Lipford, H Wagner	The EMBO Journal	1998
Cell activation mediated by glycosylphosphatidylinositol-anchored or transmembrane forms of CD14 J Pugin, VV Kravchenko, JD Lee, L Kline, RJ Ulevitch, PS Tobias	Infection and immunity	1998
SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis S Ganiatsas, L Kwee, Y Fujiwara, A Perkins, T Ikeda, MA Labow, LI Zon	Proceedings of the National Academy of Sciences	1998
UV irradiation induces the murine urokinase-type plasminogen activator gene via the c-Jun N-terminal kinase signaling pathway: requirement of an AP1 enhancer element F Miralles, M Parra, C Caelles, Y Nagamine, J Félez, P Muñoz-Cánoves	Molecular and cellular biology	1998
A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase T Fox, JT Coll, X Xie, PJ Ford, UA Germann, MD Porter, S Pazhanisamy, MA Fleming, V Galullo, MS Su, KP Wilson	Protein science : a publication of the Protein Society	1998
Cloning of a novel gene in the human kidney homologous to rat munc13s: Its potential role in diabetic nephropathy Y Song, M Ailenberg, M Silverman	Kidney International	1998
Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNK MAPK pathways M Takekawa, T Maeda, H Saito	The EMBO Journal	1998
Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway M Rincón, H Enslen, J Raingeaud, M Recht, T Zapton, MS Su, LA Penix, RJ Davis, RA Flavell	The EMBO Journal	1998
Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1 JD Graves, Y Gotoh, KE Draves, D Ambrose, DK Han, M Wright, J Chernoff, EA Clark, EG Krebs	The EMBO Journal	1998
Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator F Posas, H Saito	The EMBO Journal	1998
Serum response factor is essential for mesoderm formation during mouse embryogenesis S Arsenian, B Weinhold, M Oelgeschläger, U Rüther, A Nordheim	The EMBO Journal	1998
Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase S Nemoto, JA DiDonato, A Lin	Molecular and cellular biology	1998
The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes M Rincón, A Whitmarsh, DD Yang, L Weiss, B Dérijard, P Jayaraj, RJ Davis, RA Flavell	Journal of Experimental Medicine	1998
JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension Y Xia, Z Wu, B Su, B Murray, M Karin	Genes & development	1998
Different protein tyrosine kinases are required for B cell antigen receptor-mediated activation of extracellular signal-regulated kinase, c-Jun NH2-terminal kinase 1, and p38 mitogen-activated protein kinase A Jiang, A Craxton, T Kurosaki, EA Clark	Journal of Experimental Medicine	1998
Coordinate activation of activator protein 1 and inflammatory cytokines in response to Neisseria gonorrhoeae epithelial cell contact involves stress response kinases M Naumann, T Rudel, B Wieland, C Bartsch, TF Meyer	Journal of Experimental Medicine	1998
Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase M Takahashi-Tezuka, Y Yoshida, T Fukada, T Ohtani, Y Yamanaka, K Nishida, K Nakajima, M Hibi, T Hirano	Molecular and cellular biology	1998
Adenovirus E1B 19,000-molecular-weight protein activates c-Jun N-terminal kinase and c-Jun-mediated transcription RH See, Y Shi	Molecular and cellular biology	1998
Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by the G-protein-coupled receptor agonist phenylephrine in the perfused rat heart A Lazou, PH Sugden, A Clerk	Biochemical Journal	1998
A conserved p38 mitogen-activated protein kinase pathway regulates Drosophila immunity gene expression ZS Han, H Enslen, X Hu, X Meng, IH Wu, T Barrett, RJ Davis, YT Ip	Molecular and cellular biology	1998
Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation J Xing, JM Kornhauser, Z Xia, EA Thiele, ME Greenberg	Molecular and cellular biology	1998
A splicing variant of a death domain protein that is regulated by a mitogen-activated kinase is a substrate for c-Jun N-terminal kinase in the human central nervous system Y Zhang, L Zhou, CA Miller	Proceedings of the National Academy of Sciences	1998
Epidermal growth factor induction of the c-jun promoter by a Rac pathway N Clarke, N Arenzana, T Hai, A Minden, R Prywes	Molecular and cellular biology	1998
Activation of stress-activated MAP protein kinases up-regulates expression of transgenes driven by the cytomegalovirus immediate/early promoter W Bruening, B Giasson, W Mushynski, HD Durham	Nucleic Acids Research	1998
Insulin-stimulated expression of c-fos, fra1 and c-jun accompanies the activation of the activator protein-1 (AP-1) transcriptional complex MR Griffiths, EJ Black, AA Culbert, M Dickens, PE Shaw, DA Gillespie, JM Tavaré	Biochemical Journal	1998
CDC42 and FGD1 cause distinct signaling and transforming activities IP Whitehead, K Abe, JL Gorski, CJ Der	Molecular and cellular biology	1998
Heat stress activates fission yeast Spc1/StyI MAPK by a MEKK-independent mechanism K Shiozaki, M Shiozaki, P Russell	Molecular biology of the cell	1998
Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase I Rogatsky, SK Logan, MJ Garabedian	Proceedings of the National Academy of Sciences	1998
Endothelin-1-induced mesangial cell contraction involves activation of protein kinase C-α, -δ, and -ε JA Dlugosz, S Munk, X Zhou, CI Whiteside	American journal of physiology. Renal physiology	1998
Arachidonic acid potentiates the feedback response of mesangial BK Ca channels to angiotensin II JD Stockand, M Silverman, D Hall, T Derr, B Kubacak, SC Sansom	American journal of physiology. Renal physiology	1998
Inactivation of kinase cascades in mesangial cells grown on collagen type I T Miralem, DM Templeton	American journal of physiology. Renal physiology	1998
Induction of c- fos Proto-oncogene in Mesangial Cells by Cadmium Z Wang, DM Templeton	The Journal of biological chemistry	1998
Endocrinology of Cardiovascular Function ER Levin, JL Nadler		1998
Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons A Eilers, J Whitfield, C Babij, L L Rubin, J Ham	The Journal of neuroscience : the official journal of the Society for Neuroscience	1998
Motoneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway A C Maroney, M A Glicksman, A N Basma, K M Walton, E Knight Jr, C A Murphy, B A Bartlett, J P Finn, T Angeles, Y Matsuda, N T Neff, C A Dionne	The Journal of neuroscience : the official journal of the Society for Neuroscience	1998
Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons A Watson, A Eilers, D Lallemand, J Kyriakis, L L Rubin, J Ham	The Journal of neuroscience : the official journal of the Society for Neuroscience	1998
In vivo expression and regulation of Elk-1, a target of the extracellular-regulated kinase signaling pathway, in the adult rat brain V Sgambato, P Vanhoutte, C Pagès, M Rogard, R Hipskind, M J Besson, J Caboche	The Journal of neuroscience : the official journal of the Society for Neuroscience	1998
Interleukin-1β Expression after Inhibition of Protein Phosphatases in Endotoxin-Tolerant Cells BK Yoza, JD Wells, CE McCall	Clinical and diagnostic laboratory immunology	1998
Common and distinct intracellular signaling pathways in human neutrophils utilized by platelet activating factor and FMLP JA Nick, NJ Avdi, SK Young, C Knall, P Gerwins, GL Johnson, GS Worthen	Journal of Clinical Investigation	1997
Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats D Koya, MR Jirousek, YW Lin, H Ishii, K Kuboki, GL King	Journal of Clinical Investigation	1997
Regulation of filtration rate by glomerular mesangial cells in health and diabetic renal disease JD Stockand, SC Sansom	American Journal of Kidney Diseases	1997
Pathogenesis of diabetic nephropathy R Kikkawa, M Haneda	Clinical and Experimental Nephrology	1997
Mesangial cell actin disassembly in high glucose mediated by protein kinase C and the polyol pathway X Zhou, C Li, J Dlugosz, J Kapor-Drezgic, S Munk, C Whiteside	Kidney International	1997
A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression D Zechner, DJ Thuerauf, DS Hanford, PM McDonough, CC Glembotski	The Journal of Cell Biology	1997
Preferential activation of the p46 isoform of JNK/SAPK in mouse macrophages by TNF alpha ED Chan, BW Winston, MB Jarpe, MW Wynes, DW Riches	Proceedings of the National Academy of Sciences	1997
Adenovirus infection stimulates the Raf/MAPK signaling pathway and induces interleukin-8 expression JT Bruder, I Kovesdi	Journal of virology	1997
Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinases C Knall, GS Worthen, GL Johnson	Proceedings of the National Academy of Sciences	1997
Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes H Nishina, M Bachmann, AJ Oliveira-dos-Santos, I Kozieradzki, KD Fischer, B Odermatt, A Wakeham, A Shahinian, H Takimoto, A Bernstein, TW Mak, JR Woodgett, PS Ohashi, JM Penninger	Journal of Experimental Medicine	1997
Mast cell tumor necrosis factor alpha production is regulated by MEK kinases T Ishizuka, N Terada, P Gerwins, E Hamelmann, A Oshiba, GR Fanger, GL Johnson, EW Gelfand	Proceedings of the National Academy of Sciences	1997
Sodium salicylate induces apoptosis via p38 mitogen-activated protein kinase but inhibits tumor necrosis factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activation P Schwenger, P Bellosta, I Vietor, C Basilico, EY Skolnik, J Vilcek	Proceedings of the National Academy of Sciences	1997
Effect of inhibition of aldose reductase on glucose flux, diacylglycerol formation, protein kinase C, and phospholipase A2 activation RJ Keogh, ME Dunlop, RG Larkins	Metabolism	1997
Protective effect of d-α-tocopherol on the function of human mesangial cells exposed to high glucose concentrations H Tada, H Ishii, S Isogai	Metabolism	1997
Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38) A Cuenda, P Cohen, V Buée-Scherrer, M Goedert	The EMBO Journal	1997
MAP kinase- and Rho-dependent signals interact to regulate gene expression but not actin morphology in cardiac muscle cells J Thorburn, S Xu, A Thorburn	The EMBO Journal	1997
MAP kinase- and Rho-dependent signals interact to regulate gene expression but not actin morphology in cardiac muscle cells J Thorburn, S Xu, A Thorburn	The EMBO Journal	1997
A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses T Moriguchi, F Toyoshima, N Masuyama, H Hanafusa, Y Gotoh, E Nishida	The EMBO Journal	1997
NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain YC Su, J Han, S Xu, M Cobb, EY Skolnik	The EMBO Journal	1997
Tumor necrosis factor alpha-induced activation of c-jun N-terminal kinase is mediated by TRAF2 C Reinhard, B Shamoon, V Shyamala, LT Williams	The EMBO Journal	1997
BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C Y Kato, VV Kravchenko, RI Tapping, J Han, RJ Ulevitch, JD Lee	The EMBO Journal	1997
A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways M Takekawa, F Posas, H Saito	The EMBO Journal	1997
Convergence of MAP kinase pathways on the ternary complex factor Sap-1a R Janknecht, T Hunter	The EMBO Journal	1997
Ligation of major histocompatability complex (MHC) class I molecules on human T cells induces cell death through PI-3 kinase-induced c-Jun NH2-terminal kinase activity: a novel apoptotic pathway distinct from Fas-induced apoptosis S Skov, P Klausen, MH Claesson	The Journal of Cell Biology	1997
Molecular cloning and characterization of human JNKK2, a novel Jun NH2-terminal kinase-specific kinase Z Wu, J Wu, E Jacinto, M Karin	Molecular and cellular biology	1997
Fas induces cytoplasmic apoptotic responses and activation of the MKK7-JNK/SAPK and MKK6-p38 pathways independent of CPP32-like proteases F Toyoshima, T Moriguchi, E Nishida	The Journal of Cell Biology	1997
Thrombin produces phosphorylation of cytosolic phospholipase A2 by a mitogen-activated protein kinase kinase-independent mechanism in the human astrocytoma cell line 1321N1 M Hernández, Y Bayón, MS Crespo, ML Nieto	Biochemical Journal	1997
Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-alpha) translation: glucocorticoids inhibit TNF-alpha translation by blocking JNK/SAPK JL Swantek, MH Cobb, TD Geppert	Molecular and cellular biology	1997
Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase K Diener, XS Wang, C Chen, CF Meyer, G Keesler, M Zukowski, TH Tan, Z Yao	Proceedings of the National Academy of Sciences	1997
The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents D Wilhelm, K Bender, A Knebel, P Angel	Molecular and cellular biology	1997
Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase C Tournier, AJ Whitmarsh, J Cavanagh, T Barrett, RJ Davis	Proceedings of the National Academy of Sciences	1997
Ribotoxic stress response: activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alpha-sarcin/ricin loop in the 28S rRNA MS Iordanov, D Pribnow, JL Magun, TH Dinh, JA Pearson, SL Chen, BE Magun	Molecular and cellular biology	1997
Discrete roles of the Spc1 kinase and the Atf1 transcription factor in the UV response of Schizosaccharomyces pombe G Degols, P Russell	Molecular and cellular biology	1997
Downstream of Crk adaptor signaling pathway: activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G S Tanaka, T Ouchi, H Hanafusa	Proceedings of the National Academy of Sciences	1997
The structure of mitogen-activated protein kinase p38 at 2.1-A resolution Z Wang, PC Harkins, RJ Ulevitch, J Han, MH Cobb, EJ Goldsmith	Proceedings of the National Academy of Sciences	1997
Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity D Yang, C Tournier, M Wysk, HT Lu, J Xu, RJ Davis, RA Flavell	Proceedings of the National Academy of Sciences	1997
Lipopolysaccharide and Raf-1 kinase regulate secretory interleukin-1 receptor antagonist gene expression by mutually antagonistic mechanisms CJ Guthridge, D Eidlen, WP Arend, A Gutierrez-Hartmann, MF Smith	Molecular and cellular biology	1997
Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases P Juo, CJ Kuo, SE Reynolds, RF Konz, J Raingeaud, RJ Davis, HP Biemann, J Blenis	Molecular and cellular biology	1997
Positioning atypical protein kinase C isoforms in the UV-induced apoptotic signaling cascade E Berra, MM Municio, L Sanz, S Frutos, MT Diaz-Meco, J Moscat	Molecular and cellular biology	1997
A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses T Moriguchi, F Toyoshima, N Masuyama, H Hanafusa, Y Gotoh, E Nishida	The EMBO Journal	1997
BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C Y Kato, VV Kravchenko, RI Tapping, J Han, RJ Ulevitch, JD Lee	The EMBO Journal	1997
A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways M Takekawa, F Posas, H Saito	The EMBO Journal	1997
Differential disposition of lysophosphatidylcholine in diabetes compared with raised glucose: implications for prostaglandin production in the diabetic kidney glomerulus in vivo ME Dunlop, E Muggli, S Clark	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1997
Nitric Oxide and the Kidney MS Goligorsky, SS Gross		1997
Study of proline-directed protein kinases involved in phosphorylation of the heavy neurofilament subunit B I Giasson, W E Mushynski	The Journal of neuroscience : the official journal of the Society for Neuroscience	1997
Mitogen-activated protein kinase phosphatase-1 in rat arterial smooth muscle cell proliferation K Lai, H Wang, WS Lee, MK Jain, ME Lee, E Haber	Journal of Clinical Investigation	1996
Selective activation of the mitogen-activated protein kinase subgroups c-Jun NH2 terminal kinase and p38 by IL-1 and TNF in human articular chondrocytes Y Geng, J Valbracht, M Lotz	Journal of Clinical Investigation	1996
SYMPOSIUM: Experimental Biology 1995 Role of Mesangial Cell Ion Transport in Glomerular Physiology and Disease: PHYSIOLOGICAL ROLE OF LARGE, Ca2+-ACTIVATED K+ CHANNELS IN HUMAN GLOMERULAR MESANGIAL CELLS SC Sansom, JD Stockand	Clinical and Experimental Pharmacology and Physiology	1996
Production of hyaluronan by glomerular mesangial cells in response to fibronectin and platelet-derived growth factor ME Dunlop, S Clark, P Mahadevan, E Muggli, RG Larkins	Kidney International	1996
Urea-inducible Egr-1 transcription in renal inner medullary collecting duct (mIMCD3) cells is mediated by extracellular signal-regulated kinase activation DM Cohen	Proceedings of the National Academy of Sciences	1996
Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling DT Denhardt	Biochemical Journal	1996
The relationship between plasma insulin level, prostaglandin production by adipose tissue, and blood pressure in normal rats and rats with diabetes mellitus and diabetic ketoacidosis K Chatzipanteli, C Head, J Megerman, L Axelrod	Metabolism	1996
The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor J Raingeaud, S Gupta, JS Rogers, M Dickens, J Han, RJ Ulevitch, RJ Davis	The EMBO Journal	1996
MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6 LA Tibbles, YL Ing, F Kiefer, J Chan, N Iscove, JR Woodgett, NJ Lassam	The EMBO Journal	1996
HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway F Kiefer, LA Tibbles, M Anafi, A Janssen, BW Zanke, N Lassam, T Pawson, JR Woodgett, NN Iscove	The EMBO Journal	1996
The p38 and ERK MAP kinase pathways cooperate to activate Ternary Complex Factors and c-fos transcription in response to UV light MA Price, FH Cruzalegui, R Treisman	The EMBO Journal	1996
The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase M Cavigelli, WW Li, A Lin, B Su, K Yoshioka, M Karin	The EMBO Journal	1996
rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation DJ Sulciner, K Irani, ZX Yu, VJ Ferrans, P Goldschmidt-Clermont, T Finkel	Molecular and cellular biology	1996
3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathways S Ludwig, K Engel, A Hoffmeyer, G Sithanandam, B Neufeld, D Palm, M Gaestel, UR Rapp	Molecular and cellular biology	1996
FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2 Y Tan, J Rouse, A Zhang, S Cariati, P Cohen, MJ Comb	The EMBO Journal	1996
Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress- and cytokine-stimulated monocytes and epithelial cells A Cuenda, G Alonso, N Morrice, M Jones, R Meier, P Cohen, AR Nebreda	The EMBO Journal	1996
Newly identified stress-responsive protein kinases, Krs-1 and Krs-2 LK Taylor, HC Wang, RL Erikson	Proceedings of the National Academy of Sciences	1996
UV irradiation-induced apoptosis leads to activation of a 36-kDa myelin basic protein kinase in HL-60 cells ML Lu, M Sato, B Cao, JP Richie	Proceedings of the National Academy of Sciences	1996
Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase LA Groom, AA Sneddon, DR Alessi, S Dowd, SM Keyse	The EMBO Journal	1996
The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability T Tanaka, M Kurokawa, K Ueki, K Tanaka, Y Imai, K Mitani, K Okazaki, N Sagata, Y Yazaki, Y Shibata, T Kadowaki, H Hirai	Molecular and cellular biology	1996
Actions of Rho family small G proteins and p21-activated protein kinases on mitogen-activated protein kinase family members JA Frost, S Xu, MR Hutchison, S Marcus, MH Cobb	Molecular and cellular biology	1996
Raf, but not MEK or ERK, is sufficient for differentiation of hippocampal neuronal cells WL Kuo, M Abe, J Rhee, EM Eves, SA McCarthy, M Yan, DJ Templeton, M McMahon, MR Rosner	Molecular and cellular biology	1996
Selective interaction of JNK protein kinase isoforms with transcription factors S Gupta, T Barrett, AJ Whitmarsh, J Cavanagh, HK Sluss, B Dérijard, RJ Davis	The EMBO Journal	1996
A tyrosine kinase profile of prostate carcinoma D Robinson, F He, T Pretlow, HJ Kung	Proceedings of the National Academy of Sciences	1996
Activation and regulation of the Spc1 stress-activated protein kinase in Schizosaccharomyces pombe G Degols, K Shiozaki, P Russell	Molecular and cellular biology	1996
The Ras-Raf pathway is activated in human immunodeficiency virus-infected monocytes and particpates in the activation of NF-kappa B L Folgueira, A Algeciras, WS MacMorran, GD Bren, CV Paya	Journal of virology	1996
CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency PS Cohen, H Nakshatri, J Dennis, T Caragine, M Bianchi, A Cerami, KJ Tracey	Proceedings of the National Academy of Sciences	1996
Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase A Salmeron, TB Ahmad, GW Carlile, D Pappin, RP Narsimhan, SC Ley	The EMBO Journal	1996
Analysis of ATF3, a transcription factor induced by physiological stresses and modulated by gadd153/Chop10 BP Chen, CD Wolfgang, T Hai	Molecular and cellular biology	1996
Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages J Hambleton, SL Weinstein, L Lem, AL DeFranco	Proceedings of the National Academy of Sciences	1996
Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2 BS Yang, CA Hauser, G Henkel, MS Colman, CV Beveren, KJ Stacey, DA Hume, RA Maki, MC Ostrowski	Molecular and cellular biology	1996
Tyrosine kinase activation is an immediate and essential step in hypotonic cell swelling-induced ERK activation and c-fos gene expression in cardiac myocytes J Sadoshima, Z Qiu, JP Morgan, S Izumo	The EMBO Journal	1996
Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade H Enslen, H Tokumitsu, PJ Stork, RJ Davis, TR Soderling	Proceedings of the National Academy of Sciences	1996
Heparin Inhibits Mitogen-activated Protein Kinase-dependent and -independent c- fos Induction in Mesangial Cells T Miralem, A Wang, CI Whiteside, DM Templeton	The Journal of biological chemistry	1996
Regulatory role of eicosanoids in extracellular matrix overproduction induced by long-term exposure to high glucose in cultured rat mesangial cells F Pricci, G Pugliese, P Menè, G Romeo, G Romano, G Galli, A Casini, CM Rotella, UD Mario, F Pugliese	Diabetologia	1996
Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism Z Xia, H Dudek, C K Miranti, M E Greenberg	The Journal of neuroscience : the official journal of the Society for Neuroscience	1996
Na+/H+ exchange in hypertension and in diabetes mellitus?facts and hypotheses W Siffert, R Dsing	Basic Research in Cardiology	1996
Identification of the mechanism for the inhibition of Na+,K(+)-adenosine triphosphatase by hyperglycemia involving activation of protein kinase C and cytosolic phospholipase A2 P Xia, RM Kramer, GL King	Journal of Clinical Investigation	1995
Transmembrane signaling in kidney health and disease N Hack, A Schultz, P Clayman, H Goldberg, KL Skorecki	Pediatric Nephrology	1995
High glucose augments angiotensin II action by inhibiting NO synthesis in in vitro microperfused rabbit afferent arterioles S Arima, S Ito, K Omata, K Takeuchi, K Abe	Kidney International	1995
High glucose concentrations and protein kinase C isoforms in vascular smooth muscle cells H Haller, E Baur, P Quass, M Behrend, C Lindschau, A Distler, FC Luft	Kidney International	1995
Identification of the mechanism for the inhibition of Na+,K(+)-adenosine triphosphatase by hyperglycemia involving activation of protein kinase C and cytosolic phospholipase A2 P Xia, RM Kramer, GL King	Journal of Experimental Medicine	1995
Arachidonic acid and eicosanoids as targets and effectors in second messenger interactions VD Marzo	Prostaglandins, Leukotrienes and Essential Fatty Acids	1995
Protein kinase C in diabetic nephropathy PA Craven, RK Studer, H Negrete, FR DeRubertis	Journal of Diabetes and its Complications	1995
The mammalian mitogen activated protein kinase network P Lenormand	Clinical molecular pathology	1995
Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation M Cavigelli, F Dolfi, FX Claret, M Karin	The EMBO Journal	1995
Evidence for a role of MEK and MAPK during signal transduction by protein kinase C zeta E Berra, MT Díaz-Meco, J Lozano, S Frutos, MM Municio, P Sánchez, L Sanz, J Moscat	The EMBO Journal	1995
Activation of mitogen-activated protein kinase by heat shock treatment in Drosophila F Chen, M Torres, RF Duncan	Biochemical Journal	1995
The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation AB Raitano, JR Halpern, TM Hambuch, CL Sawyers	Proceedings of the National Academy of Sciences	1995
RAS signalling is abnormal in a c-raf1 MEK1 double mutant D Bottorff, S Stang, S Agellon, JC Stone	Molecular and cellular biology	1995
Dissection of stress-activated glucose transport from insulin-induced glucose transport in mammalian cells using wortmannin and ML-9 LF Barros, RB Marchant, SA Baldwin	Biochemical Journal	1995
Differential calcium dependence in the activation of c-Jun kinase and mitogen-activated protein kinase by muscarinic acetylcholine receptors in rat 1a cells FM Mitchell, M Russell, GL Johnson	Biochemical Journal	1995
RSK3 encodes a novel pp90rsk isoform with a unique N-terminal sequence: growth factor-stimulated kinase function and nuclear translocation Y Zhao, C Bjørbaek, S Weremowicz, CC Morton, DE Moller	Molecular and cellular biology	1995
A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function AD Catling, HJ Schaeffer, CW Reuter, GR Reddy, MJ Weber	Molecular and cellular biology	1995
The activation of distinct mitogen-activated protein kinase cascades is required for the stimulation of 2-deoxyglucose uptake by interleukin-1 and insulin-like growth factor-1 in KB cells GW Gould, A Cuenda, FJ Thomson, P Cohen	Biochemical Journal	1995
Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates Max protein AS Zervos, L Faccio, JP Gatto, JM Kyriakis, R Brent	Proceedings of the National Academy of Sciences	1995
Increased hyaluronan production in the glomeruli from diabetic rats: a link between glucose-induced prostaglandin production and reduced sulphated proteoglycan P Mahadevan, RG Larkins, JR Fraser, AJ Fosang, ME Dunlop	Diabetologia	1995
Increased phosphorylation of focal adhesion kinase in diabetic rat kidney glomeruli S Clark, E Muggli, NL Greca, ME Dunlop	Diabetologia	1995
High glucose can induce lipid peroxidation in the isolated rat glomeruli H Ha, SJ Yoon, KH Kim	Kidney International	1994
Cl- regulation of a Ca(2+)-activated nonselective cation channel in beta-agonist-treated fetal distal lung epithelium KG Mendelson, LR Contois, SG Tevosian, RJ Davis, KE Paulson	The American journal of physiology	1994

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