C L Karp, S H el-Safi, T A Wynn, M M Satti, A M Kordofani, F A Hashim, M Hag-Ali, F A Neva, T B Nutman, D L Sacks
Title and authors | Publication | Year |
---|---|---|
T Lymphocyte Exhaustion During Human and Experimental Visceral Leishmaniasis.
Costa-Madeira JC, Trindade GB, Almeida PHP, Silva JS, Carregaro V |
Frontiers in immunology | 2022 |
The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca2+ Homeostasis by Targeting a Unique Ion Channel.
Gupta Y, Sharma N, Singh S, Romero JG, Rajendran V, Mogire RM, Kashif M, Beach J, Jeske W, Poonam, Ogutu BR, Kanzok SM, Akala HM, Legac J, Rosenthal PJ, Rademacher DJ, Durvasula R, Singh AP, Rathi B, Kempaiah P |
Pharmaceutics | 2022 |
Centrin-deficient Leishmania mexicana confers protection against Old World visceral leishmaniasis.
Karmakar S, Volpedo G, Zhang WW, Lypaczewski P, Ismail N, Oliveira F, Oristian J, Meneses C, Gannavaram S, Kamhawi S, Hamano S, Valenzuela JG, Matlashewski G, Satoskar AR, Dey R, Nakhasi HL |
npj Vaccines | 2022 |
Potential biomarkers of immune protection in human leishmaniasis
MN Rostami, A Khamesipour |
Medical Microbiology and Immunology | 2021 |
Role of Cytokines in Experimental and Human Visceral Leishmaniasis
M Samant, U Sahu, SC Pandey, P Khare |
Frontiers in Cellular and Infection Microbiology | 2021 |
Preclinical validation of a live attenuated dermotropic Leishmania vaccine against vector transmitted fatal visceral leishmaniasis
S Karmakar, N Ismail, F Oliveira, J Oristian, WW Zhang, S Kaviraj, KP Singh, A Mondal, S Das, K Pandey, P Bhattacharya, G Volpedo, S Gannavaram, M Satoskar, S Satoskar, RM Sastry, T Oljuskin, T Sepahpour, C Meneses, S Hamano, P Das, G Matlashewski, S Singh, S Kamhawi, R Dey, JG Valenzuela, A Satoskar, HL Nakhasi |
2021 | |
Pleiotropic Effect of Hormone Insulin-Like Growth Factor-I in Immune Response and Pathogenesis in Leishmaniases
LC Reis, EM Ramos-Sanchez, FN Araujo, AF Leal, CY Ozaki, OR Sevillano, BA Uscata, H Goto, G Santos-Gomes |
Journal of Immunology Research | 2021 |
Evaluation of medullary cytokine expression and clinical and laboratory aspects in severe human visceral leishmaniasis
L de Freitas Teles, AG Viana, MS Cardoso, GR Pinheiro, GA Bento, JF Lula, T de Cássia Moreira Soares, RT Fujiwara, SF de Carvalho |
Parasite Immunology | 2021 |
Non-human primates and Leishmania immunity
S André, V Rodrigues, M Picard, R Silvestre, J Estaquier |
2020 | |
Systems and Synthetic Immunology
S Singh |
2020 | |
Liver Immunology: Principles and Practice
ME Gershwin, JM Vierling, A Tanaka, MP Manns |
2020 | |
Case Report: Severe Visceral Leishmaniasis in a Patient with HIV Coinfection Undergoing Treatment for Erythema Nodosum Leprosum
SR Aquino, LF Diniz, IT Queiroz, MA Cunha, AM Justo, ED Silva, VR Pereira, ZM Medeiros, RF Carmo |
The American journal of tropical medicine and hygiene | 2020 |
IL-10–producing Tfh cells accumulate with age and link inflammation with age-related immune suppression
M Almanan, J Raynor, I Ogunsulire, A Malyshkina, S Mukherjee, SA Hummel, JT Ingram, A Saini, MM Xie, T Alenghat, SS Way, GS Deepe, S Divanovic, H Singh, E Miraldi, AJ Zajac, AL Dent, C Hölscher, C Chougnet, DA Hildeman |
Science Advances | 2020 |
Interleukin 2 is an Upstream Regulator of CD4+ T Cells From Visceral Leishmaniasis Patients With Therapeutic Potential
SB Chauhan, R Faleiro, R Kumar, S Ng, B Singh, OP Singh, SS Singh, F Amante, F de Labastida Rivera, M Rai, J Chakravarty, D Sacks, S Nylen, S Sundar, C Engwerda |
The Journal of Infectious Diseases | 2019 |
Cytokines: Key Determinants of Resistance or Disease Progression in Visceral Leishmaniasis: Opportunities for Novel Diagnostics and Immunotherapy
A Dayakar, S Chandrasekaran, SV Kuchipudi, SK Kalangi |
Frontiers in immunology | 2019 |
IL-4 Mediated Resistance of BALB/c Mice to Visceral Leishmaniasis Is Independent of IL-4Rα Signaling via T Cells
E McFarlane, T Mokgethi, PM Kaye, R Hurdayal, F Brombacher, J Alexander, KC Carter |
Frontiers in immunology | 2019 |
Modulation of Dengue/Zika Virus Pathogenicity by Antibody-Dependent Enhancement and Strategies to Protect Against Enhancement in Zika Virus Infection
R Khandia, A Munjal, K Dhama, K Karthik, R Tiwari, YS Malik, RK Singh, W Chaicumpa |
Frontiers in immunology | 2018 |
Epitope-Binding Characteristics for Risk versus Protective DRB1 Alleles for Visceral Leishmaniasis
T Singh, M Fakiola, J Oommen, AP Singh, AK Singh, N Smith, J Chakravarty, S Sundar, JM Blackwell |
Journal of immunology (Baltimore, Md. : 1950) | 2018 |
Quantificação da IL-10 e do INF-γ em cães com ou sem sinais clínicos de infecção com Leishmania (Leishmania) chagasi
CJ do Rosário, MF Dominici, M do Socorro C.O. Braga, CA Lima, JG Pereira, FA Melo |
Pesquisa Veterinária Brasileira | 2018 |
The impact of IL-10 dynamic modulation on host immune response against visceral leishmaniasis
I Mesquita, C Ferreira, AM Barbosa, CM Ferreira, D Moreira, A Carvalho, C Cunha, F Rodrigues, RJ Dinis-Oliveira, J Estaquier, AG Castro, E Torrado, R Silvestre |
Cytokine | 2018 |
HLA-DR Class II expression on myeloid and lymphoid cells in relation to HLA-DRB1 as a genetic risk factor for visceral leishmaniasis
B Singh, M Fakiola, M Sudarshan, J Oommen, SS Singh, S Sundar, JM Blackwell |
Immunology | 2018 |
Transcriptional Profiling in Experimental Visceral Leishmaniasis Reveals a Broad Splenic Inflammatory Environment that Conditions Macrophages toward a Disease-Promoting Phenotype
F Kong, OA Saldarriaga, H Spratt, EY Osorio, BL Travi, BA Luxon, PC Melby, CR Engwerda |
PLoS pathogens | 2017 |
Immune Checkpoint Targets for Host-Directed Therapy to Prevent and Treat Leishmaniasis
R Kumar, SB Chauhan, SS Ng, S Sundar, CR Engwerda |
Frontiers in immunology | 2017 |
Anti-parasite therapy drives changes in human visceral leishmaniasis-associated inflammatory balance
T Araújo-Santos, BB Andrade, L Gil-Santana, NF Luz, PL Santos, FA de Oliveira, ML Almeida, RN de Campos, PT Bozza, RP Almeida, VM Borges |
Scientific Reports | 2017 |
Alcoholic Fractions F5 and F6 from Withania somnifera Leaves Show a Potent Antileishmanial and Immunomodulatory Activities to Control Experimental Visceral Leishmaniasis
S Chandrasekaran, J Veronica, S Sundar, R Maurya |
Frontiers in Medicine | 2017 |
Co-factor-independent phosphoglycerate mutase of Leishmania donovani modulates macrophage signalling and promotes T-cell repertoires bearing epitopes for both MHC-I and MHC-II
MK Singh, F Jamal, AK Dubey, P Shivam, S Kumari, Pushpanjali, G Ahmed, MR Dikhit, S NARAYAN, VN Das, K Pandey, KK Sinha, P DAS, SK Singh |
Parasitology | 2017 |
Vaccination with poly(D,L-lactide-co-glycolide) nanoparticles loaded with soluble Leishmania antigens and modified with a TNFα-mimicking peptide or monophosphoryl lipid A confers protection against experimental visceral leishmaniasis
M Margaroni, M Agallou, E Athanasiou, O Kammona, C Kiparissides, C Gaitanaki, E Karagouni |
International Journal of Nanomedicine | 2017 |
Adenosine generated by ectonucleotidases modulates the host immune system during visceral leishmaniasis
Vijayamahantesh, A Amit, MR Dikhit, A Mishra, AK Singh, VN Das, P Das, S Bimal |
Cytokine | 2017 |
T1/ST2 deficient mice display protection against Leishmania infantum experimental infection
KE Khalid, MS Nascimento, LA Sacramento, DL Costa, DS Lima-Júnior, V Carregaro, JS da Silva |
Acta Tropica | 2017 |
Molecular, biochemical characterization and assessment of immunogenic potential of cofactor-independent phosphoglycerate mutase against Leishmania donovani: a step towards exploring novel vaccine candidate
R Tandon, S Chandra, RK Baharia, P Misra, S Das, K Rawat, MI Siddiqi, S Sundar, A Dube |
Parasitology | 2017 |
Induction of IL-10 and TGFβ from CD4+CD25+FoxP3+ T Cells Correlates with Parasite Load in Indian Kala-azar Patients Infected with Leishmania donovani
P Bhattacharya, S Ghosh, SA Ejazi, M Rahaman, K Pandey, VN Das, P Das, RP Goswami, B Saha, N Ali, PA Bates |
PLoS neglected tropical diseases | 2016 |
Protective inflammatory response against visceral leishmaniasis with potato tuber extract: A new approach of successful therapy
D Paik, P Das, K Naskar, PK Pramanik, T Chakraborti |
Biomedicine & Pharmacotherapy | 2016 |
Compartmentalized Immune Response in Leishmaniasis: Changing Patterns throughout the Disease
A Rodríguez-Cortés, E Carrillo, S Martorell, F Todolí, A Ojeda, A Martínez-Flórez, A Urniza, J Moreno, J Alberola, S Stäger |
PloS one | 2016 |
Antigen Presenting Cells Targeting and Stimulation Potential of Lipoteichoic Acid Functionalized Lipo-Polymerosome: A Chemo-Immunotherapeutic Approach against Intracellular Infectious Disease
PK Gupta, AK Jaiswal, S Asthana, A Dube, PR Mishra |
Biomacromolecules | 2015 |
Leishmania infantum Amastigotes Trigger a Subpopulation of Human B Cells with an Immunoregulatory Phenotype
G Andreani, M Ouellet, R Menasria, AM Gomez, C Barat, MJ Tremblay, PC Melby |
PLoS neglected tropical diseases | 2015 |
Recombinant NAD-dependent SIR-2 Protein of Leishmania donovani: Immunobiochemical Characterization as a Potential Vaccine against Visceral Leishmaniasis
RK Baharia, R Tandon, T Sharma, MK Suthar, S Das, MI Siddiqi, JK Saxena, S Sunder, A Dube, RT Fujiwara |
PLoS neglected tropical diseases | 2015 |
Tumor necrosis factor-alpha deficiency impairs host defense against Streptococcus pneumoniae
DG Jeong, JH Seo, SH Heo, YK Choi, ES Jeong |
Laboratory animal research | 2015 |
Evaluation of Live Recombinant Nonpathogenic Leishmania tarentolae Expressing Cysteine Proteinase and A2 Genes as a Candidate Vaccine against Experimental Canine Visceral Leishmaniasis
M Shahbazi, F Zahedifard, T Taheri, Y Taslimi, S Jamshidi, S Shirian, N Mahdavi, M Hassankhani, Y Daneshbod, SH Zarkesh-Esfahani, B Papadopoulou, S Rafati, KK Tetteh |
PloS one | 2015 |
The Immunobiology of Interleukin-27
H Yoshida, CA Hunter |
Annual Review of Immunology | 2015 |
Is the polymorphism at position -1082 of IL-10 gene associated with visceral leishmaniasis?
Mehrdad Hajilooi, Alireza Ahmadi, Pegah Lotfi, Mohammad Matini, Davood Jafari, Ahad Bazmani, Mohammad Momeni |
IRAN J PUBLIC HEALTH | 2015 |
Analysis of human B cell response to recombinant Leishmania LPG3
MH Fatahaliha, M Hosseini, S Rasolzadeh, DS Bandi, B Baradaran, F Jadidi-Niaragh, M Yousefi |
Asian Pacific Journal of Tropical Medicine | 2015 |
Abortive T Follicular Helper Development Is Associated with a Defective Humoral Response in Leishmania infantum-Infected Macaques
V Rodrigues, M Laforge, L Campillo-Gimenez, C Soundaramourty, A Correia-de-Oliveira, RJ Dinis-Oliveira, A Ouaissi, A Cordeiro-da-Silva, R Silvestre, J Estaquier, G Silvestri |
PLoS pathogens | 2014 |
Cytokine profiles amongst Sudanese patients with visceral leishmaniasis and malaria co-infections
E Bogaart, AB Talha, M Straetemans, PF Mens, ER Adams, MP Grobusch, BY Nour, HD Schallig |
BMC Immunology | 2014 |
Immunoregulation in human American leishmaniasis: balancing pathology and protection
KJ Gollob, AG Viana, WO Dutra |
Parasite Immunology | 2014 |
Dual Immune Modulatory Effect of Vitamin A in Human Visceral Leishmaniasis
Bruna L. Lima Maciel, Joanna Gardel Valverde, João Firmino Rodrigues-Neto, Francisco Freire-Neto, Tatjana S. L. Keesen, Selma Maria Bezerra Jeronimo |
PloS one | 2014 |
Growth Factor and Th2 Cytokine Signaling Pathways Converge at STAT6 to Promote Arginase Expression in Progressive Experimental Visceral Leishmaniasis
EY Osorio, BL Travi, AM da Cruz, OA Saldarriaga, AA Medina, PC Melby |
PLoS pathogens | 2014 |
Antibody Fc
MA Lindorfer, J Köhl, RP Taylor |
Antibody Fc | 2014 |
IL-4 contributes to failure, and colludes with IL-10 to exacerbate Leishmania donovani infection following administration of a subcutaneous leishmanial antigen vaccine
S Bhowmick, R Ravindran, N Ali |
BMC Microbiology | 2014 |
Immunotherapy and targeted therapies in treatment of visceral leishmaniasis: current status and future prospects
OP Singh, S Sundar |
Frontiers in immunology | 2014 |
Protection and pathology during parasite infection: IL-10 strikes the balance
SA Redpath, NM Fonseca, G Perona-Wright |
Parasite Immunology | 2014 |
A Defective Oxidative Burst and Impaired Antigen Presentation are Hallmarks of Human Visceral Leishmaniasis
S Roy, D Mukhopadhyay, S Mukherjee, S Ghosh, S Kumar, K Sarkar, D Pal, P Bhowmik, K Mandal, D Modak, SK Guha, N Pramanik, RP Goswami, B Saha, M Chatterjee |
2014 | |
Insights into the possible role of IFNG and IFNGR1 in Kala-azar and Post Kala-azar Dermal Leishmaniasis in Sudanese patients
MA Salih, M Fakiola, MH Abdelraheem, BM Younis, AM Musa, AM ElHassan, JM Blackwell, ME Ibrahim, HS Mohamed |
BMC Infectious Diseases | 2014 |
Transcriptional profiling of the spleen in progressive visceral leishmaniasis reveals mixed expression of type 1 and type 2 cytokine-responsive genes
CM Espitia, OA Saldarriaga, BL Travi, E Osorio, A Hernandez, M Band, MJ Patel, AA Medina, M Cappello, A Pekosz, PC Melby |
BMC Immunology | 2014 |
Bone Marrow Parasite Burden among Patients with New World Kala-Azar is Associated with Disease Severity
JM Silva, DA Zacarias, LC de Figueiredo, MR Soares, EA Ishikawa, DL Costa, CH Costa |
The American journal of tropical medicine and hygiene | 2014 |
Is the Polymorphism at Position -1082 of IL-10 Gene Associated with Visceral Leishmaniasis?
Mehrdad HAJILOOI, Alireza AHMADI, Pegah LOTFI, Mohammad MATINI, Davood JAFARI, Ahad BAZMANI, Mohammad MOMENI |
IRAN J PUBLIC HEALTH | 2014 |
Growth Factor and Th2 Cytokine Signaling Pathways Converge at STAT6 to Promote Arginase Expression in Progressive Experimental Visceral Leishmaniasis
EY Osorio, BL Travi, AM da Cruz, OA Saldarriaga, AA Medina, PC Melby, VB Carruthers |
PLoS pathogens | 2014 |
Is the IL-10 −819 Polymorphism Associated with Visceral Leishmaniasis?
M Hajilooi, K Sardarian, M Dadmanesh, M Matini, P Lotfi, A Bazmani, MA Tabatabaiefar, MK Arababadi, M Momeni |
Inflammation | 2013 |
Case study for a vaccine against leishmaniasis
J Alvar, SL Croft, P Kaye, A Khamesipour, S Sundar, SG Reed |
Vaccine | 2013 |
In vivo and in vitro antileishmanial activity of Bungarus caeruleus snake venom through alteration of immunomodulatory activity
S Bhattacharya, P Ghosh, T De, A Gomes, A Gomes, SR Dungdung |
Experimental Parasitology | 2013 |
Clinical and Immunological Aspects of Post–Kala-Azar Dermal Leishmaniasis in Bangladesh
SP Luby, MA Bhuiyan, R Haque, MW Rahman, M Ozaki, MM Zahid, C Bern, E Kenah, S Islam, CM Ghalib, D Martin, B Goodhew, JH Maguire, KM Rahman |
The American journal of tropical medicine and hygiene | 2013 |
Involvement and interactions of different immune cells and their cytokines in human visceral leishmaniasis
P Bhattacharya, N Ali |
Revista da Sociedade Brasileira de Medicina Tropical | 2013 |
Leishmania and Leishmaniasis
A Kumar |
2013 | |
Leishmania -Infected MHC Class II high Dendritic Cells Polarize CD4 + T Cells toward a Nonprotective T-bet + IFN-γ + IL-10 + Phenotype
M Resende, D Moreira, J Augusto, J Cunha, B Neves, MT Cruz, J Estaquier, A Cordeiro-da-Silva, R Silvestre |
Journal of immunology (Baltimore, Md. : 1950) | 2013 |
Pathogenic Exploitation of Fc Activity
Halstead SB |
Antibody Fc | 2013 |
Progressive Visceral Leishmaniasis Is Driven by Dominant Parasite-induced STAT6 Activation and STAT6-dependent Host Arginase 1 Expression
EY Osorio, W Zhao, C Espitia, O Saldarriaga, L Hawel, CV Byus, BL Travi, PC Melby |
PLoS pathogens | 2012 |
T Helper1/T Helper2 Cells and Resistance/Susceptibility to Leishmania Infection: Is This Paradigm Still Relevant?
J Alexander, F Brombacher |
Frontiers in immunology | 2012 |
Immunopathogenesis of non-healing American cutaneous leishmaniasis and progressive visceral leishmaniasis
L Soong, CA Henard, PC Melby |
Seminars in Immunopathology | 2012 |
Therapeutic immunization with radio-attenuated Leishmania parasites through i.m. route revealed protection against the experimental murine visceral leishmaniasis
S Datta, M Manna, S Khanra, M Ghosh, R Bhar, A Chakraborty, S Roy |
Parasitology Research | 2012 |
T cell exhaustion in protozoan disease
JP Gigley, R Bhadra, MM Moretto, IA Khan |
Trends in Parasitology | 2012 |
Antineoplastic drug, carboplatin, protects mice against visceral leishmaniasis
T Kaur, P Makkar, K Randhawa, S Kaur |
Parasitology Research | 2012 |
Immunization with Leishmania Vaccine-Alum-BCG and Montanide ISA 720 Adjuvants Induces Low-Grade Type 2 Cytokines and High Levels of IgG2 Subclass Antibodies in the Vervet Monkey ( Chlorocebus aethiops ) Model: Alum-BCG and Montanide ISA 720 Induces Robust IgG2
JM Mutiso, JC Macharia, MM Gicheru |
Scandinavian Journal of Immunology | 2012 |
Reassessment of immune correlates in human visceral leishmaniasis as defined by cytokine release in whole blood
OP Singh, K Gidwani, R Kumar, S Nylén, SL Jones, M Boelaert, D Sacks, S Sundar |
Clinical and vaccine immunology : CVI | 2012 |
Immunogenicity and immune modulatory effects of in silico predicted L. donovani candidate peptide vaccines
ME Elfaki, EA Khalil, AS de Groot, AM Musa, A Gutierrez, BM Younis, KA Salih, AM El-Hassan |
Human Vaccines & Immunotherapeutics | 2012 |
Lipopolysaccharide-Induced Cellular Activation May Participate in the Immunopathogenesis of Visceral Leishmaniasis Alone or in HIV Coinfection
JR Santos-Oliveira, AM Da-Cruz |
International journal of microbiology | 2012 |
Progressive Visceral Leishmaniasis Is Driven by Dominant Parasite-induced STAT6 Activation and STAT6-dependent Host Arginase 1 Expression
EY Osorio, W Zhao, C Espitia, O Saldarriaga, L Hawel, CV Byus, BL Travi, PC Melby, M Olivier |
PLoS pathogens | 2012 |
Evaluation of Leishmania donovani Protein Disulfide Isomerase as a Potential Immunogenic Protein/Vaccine Candidate against Visceral Leishmaniasis
PK Kushawaha, R Gupta, CD Tripathi, S Sundar, A Dube, LC Leite |
PloS one | 2012 |
Cytokines and visceral leishmaniasis: a comparison of plasma cytokine profiles between the clinical forms of visceral leishmaniasis
AS Costa, GC Costa, DM de Aquino, VR de Mendonça, A Barral, M Barral-Netto, AJ Caldas |
Memórias do Instituto Oswaldo Cruz | 2012 |
IL-27 and IL-21 are Associated with T Cell IL-10 Responses in Human Visceral Leishmaniasis
NA Ansari, R Kumar, S Gautam, S Nylén, OP Singh, S Sundar, D Sacks |
Journal of immunology (Baltimore, Md. : 1950) | 2011 |
Restoration of IFNγR Subunit Assembly, IFNγ Signaling and Parasite Clearance in Leishmania donovani Infected Macrophages: Role of Membrane Cholesterol
S Sen, K Roy, S Mukherjee, R Mukhopadhyay, S Roy |
PLoS pathogens | 2011 |
Therapeutic Enhancement of Protective Immunity during Experimental Leishmaniasis
S Divanovic, A Trompette, JI Ashworth, MB Rao, CL Karp |
PLoS neglected tropical diseases | 2011 |
Approach to the Patient with HIV and Coinfecting Tropical Infectious Diseases
Karp CL, Mahanty S |
Tropical Infectious Diseases: Principles, Pathogens and Practice | 2011 |
Cytokines
L Cassetta, G Poli, M Alfano |
Cytokines | 2011 |
Cellular vaccination with bone marrow-derived dendritic cells pulsed with a peptide of Leishmania infantum KMP-11 and CpG oligonucleotides induces protection in a murine model of visceral leishmaniasis
M Agallou, M Margaroni, E Karagouni |
Vaccine | 2011 |
Advances in Parasitology
H Huang |
Chagas Disease, Part A | 2011 |
Post-kala-azar dermal leishmaniasis: recent developments
S Singh, U Sharma, J Mishra |
International Journal of Dermatology | 2011 |
Immunomodulation by chemotherapeutic agents against Leishmaniasis
P Saha, D Mukhopadhyay, M Chatterjee |
International Immunopharmacology | 2011 |
Use of Antimony in the Treatment of Leishmaniasis: Current Status and Future Directions
AK Haldar, P Sen, S Roy |
Molecular Biology International | 2011 |
Tropical Infectious Diseases: Principles, Pathogens and Practice
TB Nutman, JW Kazura |
Tropical Infectious Diseases: Principles, Pathogens and Practice | 2011 |
Therapeutic Enhancement of Protective Immunity during Experimental Leishmaniasis
S Divanovic, A Trompette, JI Ashworth, MB Rao, CL Karp, D McMahon-Pratt |
PLoS neglected tropical diseases | 2011 |
Restoration of IFNγR Subunit Assembly, IFNγ Signaling and Parasite Clearance in Leishmania donovani Infected Macrophages: Role of Membrane Cholesterol
S Sen, K Roy, S Mukherjee, R Mukhopadhyay, S Roy, DL Sacks |
PLoS pathogens | 2011 |
Identification of Small Molecule Lead Compounds for Visceral Leishmaniasis Using a Novel Ex Vivo Splenic Explant Model System
Y Osorio, BL Travi, AR Renslo, AG Peniche, PC Melby, TG Geary |
PLoS neglected tropical diseases | 2011 |
Evidence That Lipopolisaccharide May Contribute to the Cytokine Storm and Cellular Activation in Patients with Visceral Leishmaniasis
JR Santos-Oliveira, EG Regis, CR Leal, RV Cunha, PT Bozza, AM Da-Cruz, EM Carvalho |
PLoS neglected tropical diseases | 2011 |
Elongation Factor-2, a Th1 Stimulatory Protein of Leishmania donovani , Generates Strong IFN-γ and IL-12 Response in Cured Leishmania -Infected Patients/Hamsters and Protects Hamsters against Leishmania Challenge
PK Kushawaha, R Gupta, S Sundar, AA Sahasrabuddhe, A Dube |
Journal of immunology (Baltimore, Md. : 1950) | 2011 |
Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes
SB Halstead, S Mahalingam, MA Marovich, S Ubol, DM Mosser |
The Lancet Infectious Diseases | 2010 |
Immune evasive mechanisms contributing to persistent Leishmania donovani infection
S Stäger, T Joshi, R Bankoti |
Immunologic Research | 2010 |
Murine visceral leishmaniasis: IgM and polyclonal B-cell activation lead to disease exacerbation
E Deak, A Jayakumar, KW Cho, K Goldsmith-Pestana, B Dondji, JD Lambris, D McMahon-Pratt |
European Journal of Immunology | 2010 |
Quantification of parasite load in clinical samples of leishmaniasis patients: IL-10 level correlates with parasite load in visceral leishmaniasis
S Verma, R Kumar, GK Katara, LC Singh, NS Negi, V Ramesh, P Salotra |
PloS one | 2010 |
Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases
VG Fowler, WM Scheld, AS Bayer |
Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases | 2010 |
A Curative Immune Profile One Week after Treatment of Indian Kala-Azar Patients Predicts Success with a Short-Course Liposomal Amphotericin B Therapy
S Mondal, P Bhattacharya, M Rahaman, N Ali, RP Goswami, P Sinnis |
PLoS neglected tropical diseases | 2010 |
Immunostimulatory Properties of Dendritic Cells after Leishmania donovani Infection Using an In Vitro Model of Liver Microenvironment
L Donaghy, F Cabillic, A Corlu, O Rostan, O Toutirais, C Guguen-Guillouzo, C Guiguen, JP Gangneux, A Rodriguez |
PLoS neglected tropical diseases | 2010 |
Novel role for the double-stranded RNA-activated protein kinase PKR: modulation of macrophage infection by the protozoan parasite Leishmania
RM Pereira, KL Teixeira, V Barreto-de-Souza, TC Calegari-Silva, LD De-Melo, DC Soares, DC Bou-Habib, AM Silva, EM Saraiva, UG Lopes |
The FASEB Journal | 2010 |
Molecular detection of host cytokine expression in Helicobacter pylori infected patients via semi-quantitative RT-PCR
ME Hosseini, A Oghalaie, G Habibi, A Nahvijoo, ZM Hosseini, M Tashakoripoor, M Mohammadi |
Indian Journal of Medical Microbiology | 2010 |
B7-H1 blockade increases survival of dysfunctional CD8(+) T cells and confers protection against Leishmania donovani infections
T Joshi, S Rodriguez, V Perovic, IA Cockburn, S Stäger |
PLoS pathogens | 2009 |
Tracing immunity to human leishmaniasis
S Nylén, H Akuffo |
Future Microbiology | 2009 |
Homeostatic regulation of T effector to Treg ratios in an area of seasonal malaria transmission
OC Finney, D Nwakanma, DJ Conway, M Walther, EM Riley |
European Journal of Immunology | 2009 |
KMP-11 DNA immunization significantly protects against L. donovani infection but requires exogenous IL-12 as an adjuvant for comparable protection against L. major
S Bhaumik, R Basu, S Sen, K Naskar, S Roy |
Vaccine | 2009 |
Complete protection against experimental visceral leishmaniasis with complete soluble antigen from attenuated Leishmania donovani promastigotes involves Th1-immunity and down-regulation of IL-10
SK Bhaumik, K Naskar, T De |
European Journal of Immunology | 2009 |
Leprosy coinfection with kala-azar
A Rijal, S Rijal, S Bhandari |
International Journal of Dermatology | 2009 |
Sub-optimal dose of Sodium Antimony Gluconate (SAG)-diperoxovanadate combination clears organ parasites from BALB/c mice infected with antimony resistant Leishmania donovani by expanding antileishmanial T-cell repertoire and increasing IFN-γ to IL-10 ratio
AK Haldar, S Banerjee, K Naskar, D Kalita, NS Islam, S Roy |
Experimental Parasitology | 2009 |
Immunoactivation and immunopathogeny during active visceral leishmaniasis
H Goto, MG Prianti |
Revista do Instituto de Medicina Tropical de São Paulo | 2009 |
Phagocyte-Pathogen Interactions: Macrophages and the Host Response to Infection
DG Russell, S Gordon |
2009 | |
IL-27 Regulates IL-10 and IL-17 from CD4 + Cells in Nonhealing Leishmania major Infection
CF Anderson, JS Stumhofer, CA Hunter, D Sacks |
Journal of immunology (Baltimore, Md. : 1950) | 2009 |
Immunization with the DNA-Encoding N-Terminal Domain of Proteophosphoglycan of Leishmania donovani Generates Th1-Type Immunoprotective Response against Experimental Visceral Leishmaniasis
M Samant, R Gupta, S Kumari, P Misra, P Khare, PK Kushawaha, AA Sahasrabuddhe, A Dube |
Journal of immunology (Baltimore, Md. : 1950) | 2009 |
IL-10: The Master Regulator of Immunity to Infection
KN Couper, DG Blount, EM Riley |
Journal of immunology (Baltimore, Md. : 1950) | 2008 |
A detrimental role for IgG and FcgammaR in Leishmania mexicana infection
LU Buxbaum |
Immunologic Research | 2008 |
Immunization with the cysteine proteinase Ldccys1 gene from Leishmania (Leishmania) chagasi and the recombinant Ldccys1 protein elicits protective immune responses in a murine model of visceral leishmaniasis
JH Ferreira, LG Gentil, SS Dias, CE Fedeli, S Katz, CL Barbiéri |
Vaccine | 2008 |
Could the lower frequency of CD8+CD18+CD45RO+ lymphocytes be biomarkers of human VL?
J Clarencio, CI de Oliveira, C Favali, O Medina, A Caldas, CH Costa, DL Costa, C Brodskyn, A Barral, M Barral-Netto |
International Immunology | 2008 |
Can type-1 responses against intracellular pathogens be T helper 2 cytokine dependent?
J Alexander, E McFarlane |
Microbes and Infection | 2008 |
Leishmania donovani: Role of CD2 on CD4+ T-cell function in Visceral Leishmaniasis
S Bimal, SK Singh, S Sinha, K Pandey, PK Sinha, A Ranjan, SK Bhattacharya, P Das |
Experimental Parasitology | 2008 |
Macrophage and T-Cell Gene Expression in a Model of Early Infection with the Protozoan Leishmania chagasi
NA Ettinger, ME Wilson, G Matlashewski |
PLoS neglected tropical diseases | 2008 |
Kinesin Motor Domain of Leishmania donovani as a Future Vaccine Candidate
A Dey, P Sharma, NS Redhu, S Singh |
Clinical and vaccine immunology : CVI | 2008 |
Immunological and Genetic Evidence for a Crucial Role of IL-10 in Cutaneous Lesions in Humans Infected with Leishmania braziliensis
A Salhi, V Rodrigues, F Santoro, H Dessein, A Romano, LR Castellano, M Sertorio, S Rafati, C Chevillard, A Prata, A Alcaïs, L Argiro, A Dessein |
Journal of immunology (Baltimore, Md. : 1950) | 2008 |
Interleukin-10 and the pathogenesis of human visceral leishmaniasis
S Nylén, D Sacks |
Trends in Immunology | 2007 |
Atypical cutaneous leishmaniasis cases display elevated antigen-induced interleukin-10
B Rodriguez, R Beatty, A Belli, A Barreto, X Palacios, F Marin, E Harris |
Parasite Immunology | 2007 |
Evaluation of transformation growth factor β1, interleukin-10, and interferon-γ in male symptomatic and asymptomatic dogs naturally infected by Leishmania (Leishmania) chagasi
AP Corrêa, AC Dossi, RO Vasconcelos, DP Munari, VM de Lima |
Veterinary Parasitology | 2007 |
Immunogenicity of the P-8 amastigote antigen in the experimental model of canine visceral leishmaniasis
E Carrillo, S Ahmed, K Goldsmith-Pestana, J Nieto, Y Osorio, B Travi, J Moreno, D McMahon-Pratt |
Vaccine | 2007 |
Analysis of the cytokine profile in spleen cells from dogs naturally infected by Leishmania chagasi
RS Lage, GC Oliveira, SU Busek, LL Guerra, RC Giunchetti, R Corrêa-Oliveira, AB Reis |
Veterinary Immunology and Immunopathology | 2007 |
Leishmania infantum: Mixed T-helper-1/T-helper-2 immune response in experimentally infected BALB/c mice
N Rolão, S Cortes, S Gomes-Pereira, L Campino |
Experimental Parasitology | 2007 |
Splenic accumulation of IL-10 mRNA in T cells distinct from CD4 + CD25 + (Foxp3) regulatory T cells in human visceral leishmaniasis
S Nylén, R Maurya, L Eidsmo, KD Manandhar, S Sundar, D Sacks |
Journal of Experimental Medicine | 2007 |
CD4 + CD25 − Foxp3 − Th1 cells are the source of IL-10–mediated immune suppression in chronic cutaneous leishmaniasis
CF Anderson, M Oukka, VJ Kuchroo, D Sacks |
Journal of Experimental Medicine | 2007 |
Monocyte subpopulations and their differentiation patterns during infection
D Strauss-Ayali, SM Conrad, DM Mosser |
Journal of leukocyte biology | 2007 |
Splenic immune responses during canine visceral leishmaniasis
D Strauss-Ayali, G Baneth, CL Jaffe |
Veterinary Research | 2007 |
IL-10- and TGF-β-Mediated Susceptibility in Kala-azar and Post-kala-azar Dermal Leishmaniasis: The Significance of Amphotericin B in the Control of Leishmania donovani Infection in India
S Saha, S Mondal, R Ravindran, S Bhowmick, D Modak, S Mallick, M Rahman, S Kar, R Goswami, SK Guha, N Pramanik, B Saha, N Ali |
Journal of immunology (Baltimore, Md. : 1950) | 2007 |
Hybrid Cell Vaccination Resolves Leishmania donovani Infection by Eliciting a Strong CD8 + Cytotoxic T-Lymphocyte Response with Concomitant Suppression of Interleukin-10 (IL-10) but Not IL-4 or IL-13
R Basu, S Bhaumik, AK Haldar, K Naskar, T De, SK Dana, P Walden, S Roy |
Infection and immunity | 2007 |
Activation of the MAPK, ERK, following Leishmania amazonensis Infection of Macrophages
Z Yang, DM Mosser, X Zhang |
Journal of immunology (Baltimore, Md. : 1950) | 2007 |
Reduced nitric oxide synthase 2 (NOS2) promoter activity in the Syrian hamster renders the animal functionally deficient in NOS2 activity and unable to control an intracellular pathogen
LE Perez, B Chandrasekar, OA Saldarriaga, W Zhao, LT Arteaga, BL Travi, PC Melby |
Journal of immunology (Baltimore, Md. : 1950) | 2006 |
Distinct roles for IL-6 and IL-12p40 in mediating protection againstLeishmania donovani and the expansion of IL-10+ CD4+ T cells
S Stäger, A Maroof, S Zubairi, SL Sanos, M Kopf, PM Kaye |
European Journal of Immunology | 2006 |
Approach to the Patient with HIV and Coinfecting Tropical Infectious Diseases
KARP CL, COLEBUNDERS R |
2006 | |
Mixed inflammatory/regulatory cytokine profile marked by simultaneous raise of interferon-? and interleukin-10 and low frequency of tumour necrosis factor-?+monocytes are hallmarks of active human visceral Leishmaniasis due to Leishmania chagasi infection
V Peruhype-Magalhães, OA Martins-Filho, A Prata, LD Silva, A Rabello, A Teixeira-Carvalho, RM Figueiredo, SF Guimarães-Carvalho, TC Ferrari, JV Weyenbergh, R Correa-Oliveira |
Clinical & Experimental Immunology | 2006 |
Genome-wide scan for visceral leishmaniasis susceptibility genes in Brazil
SE Jamieson, EN Miller, CS Peacock, M Fakiola, ME Wilson, A Bales-Holst, MA Shaw, F Silveira, JJ Shaw, SM Jeronimo, JM Blackwell |
Genes and Immunity | 2006 |
Multiplex analysis of circulating cytokines in the sera of patients with different clinical forms of visceral leishmaniasis
KM Kurkjian, AJ Mahmutovic, KL Kellar, R Haque, C Bern, WE Secor |
Cytometry Part A | 2006 |
The two faces of interleukin 10 in human infectious diseases
JL Mege, S Meghari, A Honstettre, C Capo, D Raoult |
The Lancet Infectious Diseases | 2006 |
Surrogate markers of immunity to Leishmania major in leishmanin skin test negative individuals from an endemic area re-visited
S Nylén, A Khamesipour, A Mohammadi, R Jafari-Shakib, L Eidsmo, S Noazin, F Modabber, H Akuffo |
Vaccine | 2006 |
Immune privilege in sites of chronic infection: Leishmania and regulatory T cells
N Peters, D Sacks |
Immunological Reviews | 2006 |
Balancing immunity and pathology in visceral leishmaniasis
AC Stanley, CR Engwerda |
Immunology and Cell Biology | 2006 |
Elevated levels of interferon-gamma, interleukin-10, and interleukin-6 during active disease in Indian kala azar
NA Ansari, S Saluja, P Salotra |
Clinical Immunology | 2006 |
Real-Time Reverse Transcription-PCR Quantification of Cytokine mRNA Expression in Golden Syrian Hamster Infected with Leishmania infantum and Treated with a New Amphotericin B Formulation
SR Iñiguez, MA Dea-Ayuela, JA Sanchez-Brunete, JJ Torrado, JM Alunda, F Bolas-Fernández |
Antimicrobial agents and chemotherapy | 2006 |
Antagonizing deactivating cytokines to enhance host defense and chemotherapy in experimental visceral leishmaniasis
HW Murray, KC Flanders, DD Donaldson, JP Sypek, PJ Gotwals, J Liu, X Ma |
Infection and immunity | 2005 |
Interleukin-12 augments a Th1-type immune response manifested as lymphocyte proliferation and interferon gamma production in Leishmania infantum-infected dogs
D Strauss-Ayali, G Baneth, S Shor, F Okano, CL Jaffe |
International Journal for Parasitology | 2005 |
T cell subset and cytokine profiles in human visceral leishmaniasis during active and asymptomatic or sub-clinical infection with Leishmania donovani
A Hailu, D Baarle, GJ Knol, N Berhe, F Miedema, PA Kager |
Clinical Immunology | 2005 |
Immunopathogenesis of infection with the visceralizing Leishmania species
ME Wilson, SM Jeronimo, RD Pearson |
Microbial Pathogenesis | 2005 |
Interleukin 10 receptor blockade—pentavalent antimony treatment in experimental visceral leishmaniasis
HW Murray |
Acta Tropica | 2005 |
Semi-quantitative analysis of cytokine expression in asymptomatic canine leishmaniasis
C Chamizo, J Moreno, J Alvar |
Veterinary Immunology and Immunopathology | 2005 |
Leishmania donovani: identification of novel vaccine candidates using human reactive sera and cell lines
SK Arora, NS Pal, S Mujtaba |
Experimental Parasitology | 2005 |
Respuesta immune a la leishmaniasis: algo más que linfocitos T
DL Bonilla-Escobar |
Piel | 2005 |
A role for IgG immune complexes during infection with the intracellular pathogen Leishmania
SA Miles, SM Conrad, RG Alves, SM Jeronimo, DM Mosser |
Journal of Experimental Medicine | 2005 |
Current understandings on the immunology of leishmaniasis and recent developments in prevention and treatment
MT Roberts |
British Medical Bulletin | 2005 |
Kinetoplastid Membrane Protein-11 DNA Vaccination Induces Complete Protection against Both Pentavalent Antimonial-Sensitive and -Resistant Strains of Leishmania donovani That Correlates with Inducible Nitric Oxide Synthase Activity and IL-4 Generation: Evidence for Mixed Th1- and Th2-Like Responses in Visceral Leishmaniasis
R Basu, S Bhaumik, JM Basu, K Naskar, T De, S Roy |
Journal of immunology (Baltimore, Md. : 1950) | 2005 |
Nonhealing Infection despite Th1 Polarization Produced by a Strain of Leishmania major in C57BL/6 Mice
CF Anderson, S Mendez, DL Sacks |
Journal of immunology (Baltimore, Md. : 1950) | 2005 |
Does the Leishmania major paradigm of pathogenesis and protection hold for New World cutaneous leishmaniases or the visceral disease?
D McMahon-Pratt, J Alexander |
Immunological Reviews | 2004 |
Re-examination of the immunosuppressive mechanisms mediating non-cure of Leishmania infection in mice
D Sacks, C Anderson |
Immunological Reviews | 2004 |
Progress in the treatment of a neglected infectious disease: visceral leishmaniasis
HW Murray |
Expert Review of Anti-infective Therapy | 2004 |
Vaccination withLeishmaniasoluble antigen and immunostimulatory oligodeoxynucleotides induces specific immunity and protection againstLeishmania donovaniinfection
P Tewary, J Mehta, B Sukumaran, R Madhubala |
FEMS Immunology & Medical Microbiology | 2004 |
Immunostimulatory oligodeoxynucleotides are potent enhancers of protective immunity in mice immunized with recombinant ORFF leishmanial antigen
P Tewary, B Sukumaran, S Saxena, R Madhubala |
Vaccine | 2004 |
Characterization of immunoglobulin G and its subclass response to Indian kala-azar infection before and after chemotherapy
R Ravindran, K Anam, BC Bairagi, B Saha, N Pramanik, SK Guha, RP Goswami, D Banerjee, N Ali |
Infection and immunity | 2004 |
Immunity and immunosuppression in experimental visceral leishmaniasis
H Goto, JA Lindoso |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] | 2004 |
Inbred Strains Derived from Feral Mice Reveal New Pathogenic Mechanisms of Experimental Leishmaniasis Due to Leishmania major
BE Babay, H Louzir, C Kebaïer, S Boubaker, K Dellagi, PA Cazenave |
Infection and immunity | 2004 |
Vaccination with DNA encoding ORFF antigen confers protective immunity in mice infected with Leishmania donovani
B Sukumaran, P Tewary, S Saxena, R Madhubala |
Vaccine | 2003 |
The role of CD4+CD25+ regulatory T cells in Leishmania infection
Y Belkaid |
Expert Opinion on Biological Therapy | 2003 |
The site of cutaneous infection influences the immunological response and clinical outcome of hamsters infected with Leishmania panamensis
Y Osorio, PC Melby, C Pirmez, B Chandrasekar, N Guarin, BL Travi |
Parasite Immunology | 2003 |
Development of a leishmaniasis vaccine: the importance of MPL
SG Reed, RN Coler, A Campos-Neto |
Expert Review of Vaccines | 2003 |
Intradermal infection model for pathogenesis and vaccine studies of murine visceral leishmaniasis
S Ahmed, M Colmenares, L Soong, K Goldsmith-Pestana, L Munstermann, R Molina, D McMahon-Pratt |
Infection and immunity | 2003 |
The Relative Contribution of IL-4 Receptor Signaling and IL-10 to Susceptibility to Leishmania major
N Noben-Trauth, R Lira, H Nagase, WE Paul, DL Sacks |
Journal of immunology (Baltimore, Md. : 1950) | 2003 |
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
Y Belkaid, CA Piccirillo, S Mendez, EM Shevach, DL Sacks |
Nature | 2002 |
IL-15 in human visceral leishmaniasis caused by Leishmania infantum
S Milano, GD Bella, P D'Agostino, C Barbera, R Caruso, ML Rosa, V Ferlazzo, G Vitale, CL Russa, G Gambino, N Chifari, S Mansueto, E Cillari |
Clinical & Experimental Immunology | 2002 |
Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy
HW Murray, CM Lu, S Mauze, S Freeman, AL Moreira, G Kaplan, RL Coffman |
Infection and immunity | 2002 |
IL-10 leads to a higher parasite persistence in a resistant mouse model of Leishmania major infection
AV da Costa, M Huerre, M Delacre, C Auriault, JM Costa, C Verwaerde |
Parasitology International | 2002 |
The immunology of susceptibility and resistance to Leishmania major in mice
D Sacks, N Noben-Trauth |
Nature Reviews Immunology | 2002 |
Leishmania
JP Farrell |
2002 | |
Gender Is a Major Determinant of the Clinical Evolution and Immune Response in Hamsters Infected with Leishmania spp
BL Travi, Y Osorio, PC Melby, B Chandrasekar, L Arteaga, NG Saravia |
Infection and immunity | 2002 |
Characterization of Leishmania donovani Antigens Encapsulated in Liposomes That Induce Protective Immunity in BALB/c Mice
F Afrin, R Rajesh, K Anam, M Gopinath, S Pal, N Ali |
Infection and immunity | 2002 |
Cytokine responses to mitogen and Schistosoma haematobium antigens are different in children with distinct infection histories
JT Scott, CR Turner, F Mutapi, ME Woolhouse, PD Ndhlovu, P Hagan |
Parasite Immunology | 2001 |
Cytokine Gene Expression in Healing and Non-Healing Cases of Cutaneous Leishmaniasis in Response to In vitro Stimulation with Recombinant gp63 Using Semi-Quantitative RT-PCR
GR Habibi, A Khamesipour, WR McMaster, F Mahboudi |
Scandinavian Journal of Immunology | 2001 |
iNOS expression by activated neutrophils from patients with sepsis
Y Tsukahara, T Morisaki, M Kojima, A Uchiyama, M Tanaka |
ANZ Journal of Surgery | 2001 |
Clinical and experimental advances in treatment of visceral leishmaniasis
HW Murray |
Antimicrobial agents and chemotherapy | 2001 |
Interleukin-13 in Iranian patients with visceral leishmaniasis: relationship to other Th2 and Th1 cytokines
Z Babaloo, PM Kaye, MB Eslami |
Transactions of the Royal Society of Tropical Medicine and Hygiene | 2001 |
Interleukin-10 and the interleukin-10 receptor
KW Moore, RW Malefyt, RL Coffman, A O'Garra |
Annual Review of Immunology | 2001 |
Immunization with A2 protein results in a mixed Th1/Th2 and a humoral response which protects mice against Leishmania donovani infections
A Ghosh, WW Zhang, G Matlashewski |
Vaccine | 2001 |
The dual role of CTLA-4 in Leishmania infection
NA Gomes, GA DosReis |
Trends in Parasitology | 2001 |
Immunology of Infectious Diseases
SH Kaufmann, A Sher, R Ahmed |
2001 | |
The Hamster as a Model of Human Visceral Leishmaniasis: Progressive Disease and Impaired Generation of Nitric Oxide in the Face of a Prominent Th1-Like Cytokine Response
PC Melby, B Chandrasekar, W Zhao, JE Coe |
Journal of immunology (Baltimore, Md. : 1950) | 2001 |
Detection of specific antibody isotypes and subtypes before and after treatment of American visceral leishmaniasis
VL da Matta, S Hoshino-Shimizu, R Dietze, CE Corbett |
Journal of Clinical Laboratory Analysis | 2000 |
Endogenous IL-4 is necessary for effective drug therapy against visceral leishmaniasis
J Alexander, KC Carter, N Al-Fasi, A Satoskar, F Brombacher |
European Journal of Immunology | 2000 |
Resistance/susceptibility to Echinococcus multilocularis infection and cytokine profile in humans. I. Comparison of patients with progressive and abortive lesions
V Godot, S Harraga, I Beurton, M Deschaseaux, E Sarciron, B Gottstein, DA Vuitton |
Clinical & Experimental Immunology | 2000 |
Treatment of visceral leishmaniasis (kala-azar): A decade of progress and future approaches
HW Murray |
International Journal of Infectious Diseases | 2000 |
Role of CD8+ T cells in endogenous interleukin-10 secretion associated with visceral leishmaniasis
BJ Holaday |
Memórias do Instituto Oswaldo Cruz | 2000 |
Early in vitro priming of distinct Th cell subsets determines polarized growth of visceralizing Leishmania in macrophages
NA Gomes, V Barreto-de-Souza, GA DosReis |
International Immunology | 2000 |
A Novel Leishmania infantum Recombinant Antigen Which Elicits Interleukin 10 Production by Peripheral Blood Mononuclear Cells of Patients with Visceral Leishmaniasis
TR Kozel, I Suffia, B Ferrua, X Stien, B Mograbi, P Marty, D Rousseau, K Fragaki, J Kubar |
Infection and immunity | 2000 |
Mitogenesis in glioblastoma multiforme cell lines: a role for NGF and its TrkA receptors
H S Singer, B Hansen, D Martinie, C L Karp |
Journal of Neuro-Oncology | 2000 |
Detection of specific antibody isotypes and subtypes before and after treatment of American visceral leishmaniasis
da Matta VL, Hoshino\u2010Shimizu S, Dietze R, Corbett CE |
Journal of Clinical Laboratory Analysis | 2000 |
Les leishmanioses: un modèle d'étude des interactions hôte-parasite; implications pour la maladie humaine
H Louzir, K Dellagi |
Annales de l'Institut Pasteur/Actualités | 1999 |
Leishmaniasis
BL Herwaldt |
The Lancet | 1999 |
Receptor mediated subversion of macrophage cytokine production by intracellular pathogens
DM Mosser, L arpt |
Current Opinion in Immunology | 1999 |
Leishmanin skin test lymphoproliferative responses and cytokine production after symptomatic or asymptomatic Leishmania major infection in Tunisia
A Sassi, H Louzir, AB Salah, M Mokni, AB Osman, K Dellagi |
Clinical & Experimental Immunology | 1999 |
Leishmania-specific T cells expressing interferon-gamma (IFN-gamma) and IL-10 upon activation are expanded in individuals cured of visceral leishmaniasis
K Kemp, M Kemp, A Kharazmi, A Ismail, JA Kurtzhals, L Hviid, TG Theander |
Clinical & Experimental Immunology | 1999 |
Differential decline in Leishmania membrane antigen-specific immunoglobulin G (IgG), IgM, IgE, and IgG subclass antibodies in Indian kala-azar patients after chemotherapy
K Anam, F Afrin, D Banerjee, N Pramanik, SK Guha, RP Goswami, SK Saha, N Ali |
Infection and immunity | 1999 |
T-cell response in human leishmaniasis
A Kharazmi, K Kemp, A Ismail, S Gasim, A Gaafar, JA Kurtzhals, AM Hassan, TG Theander, M Kemp |
Immunology Letters | 1999 |
Interferon-γ- and Tumour Necrosis Factor-α-Producing Cells in Humans who are Immune to Cutaneous Leishmaniasis: IFN-γ and TNF-α in Leishmaniasis
KEMP, THEANDER, HVIID, GARFAR, KHARAZMI, KEMP |
Scandinavian Journal of Immunology | 1999 |
Leishmania–HIV Interaction: Immunopathogenic Mechanisms
D Wolday, N Berhe, H Akuffo, S Britton |
Parasitology Today | 1999 |
Immunotherapy for Visceral Leishmaniasis: Ability of Factors Produced during Anti-leishmania Responses of Skin Test Positive Adults to Inhibit Peripheral Blood Mononuclear Cell Activities Associated with Visceral Leishmaniasis
BJ Holaday |
Memórias do Instituto Oswaldo Cruz | 1999 |
Differential Decline in Leishmania Membrane Antigen-Specific Immunoglobulin G (IgG), IgM, IgE, and IgG Subclass Antibodies in Indian Kala-Azar Patients after Chemotherapy
SH Kaufmann, K Anam, F Afrin, D Banerjee, N Pramanik, SK Guha, RP Goswami, SK Saha, N Ali |
Infection and immunity | 1999 |
Leishmania species: models of intracellular parasitism
J Alexander, AR Satoskar, DG Russell |
Journal of cell science | 1999 |
Immunoglobulin Subclass Distribution and Diagnostic Value of Leishmania donovani Antigen-Specific Immunoglobulin G3 in Indian Kala-Azar Patients
K Anam, F Afrin, D Banerjee, N Pramanik, SK Guha, RP Goswami, PN Gupta, SK Saha, N Ali |
Clinical and diagnostic laboratory immunology | 1999 |
Distribution of IgG subclasses in antimonial unresponsive Indian kala-azar patients
M Chatterjee, K Basu, D Basu, D Bannerjee, N Pramanik, SK Guha, RP Goswami, SK Saha, C Mandal |
Clinical & Experimental Immunology | 1998 |
High levels of plasma IL-10 and expression of IL-10 by keratinocytes during visceral leishmaniasis predict subsequent development of post-kala-azar dermal leishmaniasis
S Gasim, AM Elhassan, EA Khalil, A Ismail, AM Kadaru, A Kharazmi, TG Theander |
Clinical & Experimental Immunology | 1998 |
Mapping of specific and promiscuous HLA-DR-restricted T-cell epitopes on the Plasmodium falciparum 27-kilodalton sexual stage-specific antigen
CE Contreras, IN Ploton, RF Siliciano, CL Karp, R Viscidi, N Kumar |
Infection and immunity | 1998 |
Decreased mRNA Expression of Several Basement Membrane Components in Basal Cell Carcinoma
A Chopra, B Maitra, NJ Korman |
Journal of Investigative Dermatology | 1998 |
Human_Leishmaniasis@cytokines.bahia.br
M Barral-Netto, C Brodskyn, EM Carvalho, A Barral |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] | 1998 |
Presence of Circulating Levels of Interferon-g, Interleukin-10 and Tumor Necrosis Factor-a in Patients with Visceral Leishmaniasis
IM de MEDEIROS, A CASTELO, R SALOMÃO |
Revista do Instituto de Medicina Tropical de São Paulo | 1998 |
Cytokine profile and pathology in human leishmaniasis
A Ribeiro-de-Jesus, RP Almeida, H Lessa, O Bacellar, EM Carvalho |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] | 1998 |
Regional Differences in the Cellular Immune Response to Experimental Cutaneous or Visceral Infection with Leishmania donovani
PC Melby, YZ Yang, J Cheng, W Zhao |
Infection and immunity | 1998 |
Cloning of Syrian Hamster ( Mesocricetus auratus ) Cytokine cDNAs and Analysis of Cytokine mRNA Expression in Experimental Visceral Leishmaniasis
PC Melby, VV Tryon, B Chandrasekar, GL Freeman |
Infection and immunity | 1998 |
Importance of Interleukin-10 in Genetic Susceptibility of Mice to Coccidioides immitis
TR Kozel, J Fierer, L Walls, L Eckmann, T Yamamoto, TN Kirkland |
Infection and immunity | 1998 |
Interleukin-10 and interleukin-4 inhibit intracellular killing ofLeishmania infantum andLeishmania major by human macrophages by decreasing nitric oxide generation
I Vouldoukis, PA Bécherel, V Riveros-Moreno, M Arock, OD Silva, P Debré, D Mazier, MD Mossalayi |
European Journal of Immunology | 1997 |
Adjuvanticity and protective immunity elicited by Leishmania donovani antigens encapsulated in positively charged liposomes
F Afrin, N Ali |
Infection and immunity | 1997 |
Association of Leishmania heat shock protein 83 antigen and immunoglobulin G4 antibody titers in Brazilian patients with diffuse cutaneous leishmaniasis
YA Skeiky, DR Benson, JL Costa, R Badaro, SG Reed |
Infection and immunity | 1997 |
T helper type 2 like cytokine responses to peptides from P0 and P2 myelin proteins during the recovery phase of Guillain-Barré syndrome
C Dahle, C Ekerfelt, M Vrethem, M Samuelsson, J Ernerudh |
Journal of the Neurological Sciences | 1997 |
Regulator and effector functions of T-cell subsets in human Leishmanaia infections
M Kemp |
APMIS | 1997 |
Zinc-controlled Th1/Th2 switch significantly determines development of diseases
JE Sprietsma |
Medical Hypotheses | 1997 |
Behavior of Visceral Leishmania donovani in an Experimentally Induced T Helper Cell 2 (Th2)-Associated Response Model
HW Murray, J Hariprashad, RL Coffman |
Journal of Experimental Medicine | 1997 |
Cell-Mediated Immune System Regulation in Periodontal Diseases
A Mathur, BS Michalowicz |
Critical Reviews in Oral Biology & Medicine | 1997 |
Asymptomatic Leishmania chagasi Infection in Relatives and Neighbors of Patients with Visceral Leishmaniasis
AD Júnior, SR Costa, AB Barbosa, ML la Orge, EM Carvalho |
Memórias do Instituto Oswaldo Cruz | 1997 |
Evidence of a T helper type 2 activation in human schistosomiasis
MI Araújo, AR de Jesus, O Bacellar, E Sabin, E Pearce, EM Carvalho |
European Journal of Immunology | 1996 |
In situ expression of interleukin-10 and interleukin-12 in active human cutaneous leishmaniasis
PC Melby, F Andrade-Narvaez, BJ Darnell, G Valencia-Pacheco |
FEMS Immunology & Medical Microbiology | 1996 |
Early commitment to the eosinophil lineage by cultured human peripheral blood CD34+ cells: Messenger RNA analysis
M Shalit, S Sekhsaria, F Li, S Mauhorter, S Mahanti, HL Malech |
Journal of Allergy and Clinical Immunology | 1996 |
Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases
DR Lucey, M Clerici, GM Shearer |
Clinical microbiology reviews | 1996 |
Evidence for a predominant proinflammatory conjunctival cytokine response in individuals with trachoma
L Bobo, N Novak, H Mkocha, S Vitale, S West, TC Quinn |
Infection and immunity | 1996 |
Cross-modulation by transforming growth factor beta in human tuberculosis: suppression of antigen-driven blastogenesis and interferon gamma production
CS Hirsch, R Hussain, Z Toossi, G Dawood, F Shahid, JJ Ellner |
Proceedings of the National Academy of Sciences | 1996 |
Lipophosphoglycan from Leishmania suppresses agonist-induced interleukin 1 beta gene expression in human monocytes via a unique promoter sequence
DE Hatzigeorgiou, J Geng, B Zhu, Y Zhang, K Liu, WN Rom, MJ Fenton, SJ Turco, JL Ho |
Proceedings of the National Academy of Sciences | 1996 |
Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice
L Carrera, RT Gazzinelli, R Badolato, S Hieny, W Muller, R Kuhn, DL Sacks |
Journal of Experimental Medicine | 1996 |
VISCERAL LEISHMANIASIS
ME Wilson, JA Streit |
Gastroenterology Clinics of North America | 1996 |
The contrasting roles of CD4+ T cells in intracellular infections in humans: leishmaniasis as an example
M Kemp, TG Theander, A Kharazmi |
Immunology Today | 1996 |
Lipophosphoglycan from Leishmania suppresses agonist-induced interleukin 1 gene expression in human monocytes via a unique promoter sequence
DE Hatzigeorgiou, J Geng, B Zhu, Y Zhang, K Liu, WN Rom, MJ Fenton, SJ Turco, JL Ho |
Proceedings of the National Academy of Sciences | 1996 |
Interferon β-1b effects on cytokine mRNA in peripheral mononuclear cells in multiple sclerosis
PV Byskosh, AT Reder |
Multiple sclerosis (Houndmills, Basingstoke, England) | 1996 |
Mechanism of Suppression of Cell-Mediated Immunity by Measles Virus
CL Karp, M Wysocka, LM Wahl, JM Ahearn, PJ Cuomo, B Sherry, G Trinchieri, DE Griffin |
Science | 1996 |
Dichotomy of the T cell response to Leishmania antigens in patients suffering from cutaneous leishmaniasis; absence or scarcity of Th1 activity is associated with severe infections
A Gaafar, A Kharazmi, A Ismail, M Kemp, A Hey, CB Christensen, M Dafalla, AY Kadaro, AM Hassan, TG Theander |
Clinical & Experimental Immunology | 1995 |
CD28 activation promotes Th2 subset differentiation by human CD4+ cells
CL King, RJ Stupi, N Craighead, CH June, G Thyphronitis |
European Journal of Immunology | 1995 |
Switch from a type 2 to a type 1 T helper cell response and cure of established Leishmania major infection in mice is induced by combined therapy with interleukin 12 and Pentostam
GS Nabors, LC Afonso, JP Farrell, P Scott |
Proceedings of the National Academy of Sciences | 1995 |
Human T-cell activation by 14- and 18-kilodalton nuclear proteins of Leishmania infantum
I Suffia, JF Quaranta, MC Eulalio, B Ferrua, P Marty, YL Fichoux, J Kubar |
Infection and immunity | 1995 |
Allergen-stimulated interleukin-4 and interferon-gamma production in primary culture: responses of subjects with allergic rhinitis and normal controls
M Imada, FE Simons, FT Jay, KT Hayglass |
Immunology | 1995 |
Interleukin 12 is effective treatment for an established systemic intracellular infection: experimental visceral leishmaniasis
HW Murray, J Hariprashad |
Journal of Experimental Medicine | 1995 |
Disruption of the murine interleukin-4 gene inhibits disease progression during Leishmania mexicana infection but does not increase control of Leishmania donovani infection
A Satoskar, H Bluethmann, J Alexander |
Infection and immunity | 1995 |
Interleukin-10
JE de Vries, R de Waal Malefyt |
1995 | |
Dichotomy of the T cell response to Leishmania antigens in patients suffering from cutaneous leishmaniasis; absence or scarcity of Th1 activity is associated with severe infections.
Gaafar A, Kharazmi A, Ismail A, Kemp M, Hey A, Christensen CB, Dafalla M, el Kadaro AY, el Hassan AM, Theander TG |
Clinical & Experimental Immunology | 1995 |
Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus
M Clerici, TA Wynn, JA Berzofsky, SP Blatt, CW Hendrix, A Sher, RL Coffman, GM Shearer |
Journal of Clinical Investigation | 1994 |
Cytokines in the treatment of leishmaniasis: From studies of immunopathology to patient therapy
JL Ho, R Badaro, D Hatzigeorgiou, SG Reed, WD Johnson |
Biotherapy | 1994 |
Dichotomy in the human CD4+T-cell response toLeishmaniaparasites
MI Kemp, JØ Kurtzhals, AR Kharazmi, TH Theander |
APMIS | 1994 |
T lymphocytes derived from skin lesions of patients with psoriasis vulgaris express a novel cytokine pattern that is distinct from that of T helper type 1 and T helper type 2 cells
S Vollmer, A Menssen, P Trommler, D Schendel, JC Prinz |
European Journal of Immunology | 1994 |
Increased expression of proinflammatory cytokines in chronic lesions of human cutaneous leishmaniasis
PC Melby, FJ Andrade-Narvaez, BJ Darnell, G Valencia-Pacheco, VV Tryon, A Palomo-Cetina |
Infection and immunity | 1994 |
Th1 and Th2 cell-associated cytokines in experimental visceral leishmaniasis
GD Miralles, MY Stoeckle, DF McDermott, FD Finkelman, HW Murray |
Infection and immunity | 1994 |
Divergent T-cell cytokine patterns in inflammatory arthritis
AK Simon, E Seipelt, J Sieper |
Proceedings of the National Academy of Sciences | 1994 |
Limiting dilution analysis of antigen stimulated IL-4 and IFN-γ production in human mononuclear cell populations
Y Li, WP Stefura, FE Simons, FT Jay, KT Hayglass |
Journal of Immunological Methods | 1994 |
The Th1–Th2 hypothesis of HIV infection: new insights
M Clerici, GM Shearer |
Immunology Today | 1994 |
Interleukin 12 and the regulation of CD4+ T-cell subset responses during murine Leishmaniasis
FP Heinzel |
Parasitology Today | 1994 |
CD23 and IgE expression during the human immune response to cutaneous leishmaniasis : Possible role in monocyte activation
I Vouldoukis, F Issaly, C Fourcade, N Paul-Eugène, M Arock, JP Kolb, OA da Silva, L Monjour, H Poinsot, Y Tselentis, B Dugas, P Debré, MD Mossalayi |
Research in Immunology | 1994 |
Leishmania infantum Tropism: Strain genotype or host immune status?
L Gradoni, M Gramiccia |
Parasitology Today | 1994 |
Cytokines and T Cell Switching
E Gemmell, GJ Seymour |
Critical Reviews in Oral Biology & Medicine | 1994 |
Cytokines in the Treatment of Infectious Diseases
BJ Kullberg, JW Meer |
1994 | |
Lack of Evidence for the Dichotomy of T H 1 and T H 2 Predominance in HIV-Infected Individuals
C Graziosi, G Pantaleo, KR Gantt, JP Fortin, JF Demarest, OJ Cohen, RP Sékaly, AS Fauci |
Science | 1994 |
Cytokine control of parasite-specific anergy in human lymphatic filariasis. Preferential induction of a regulatory T helper type 2 lymphocyte subset
CL King, S Mahanty, V Kumaraswami, JS Abrams, J Regunathan, K Jayaraman, EA Ottesen, TB Nutman |
Journal of Clinical Investigation | 1993 |
Potential role for interleukin-10 in the immunosuppression associated with kala azar
BJ Holaday, MM Pompeu, S Jeronimo, MJ Texeira, AA Sousa, AW Vasconcelos, RD Pearson, JS Abrams, RM Locksley |
Journal of Clinical Investigation | 1993 |
T-cell and cytokine responses in leishmaniasis
SG Reed, P Scott |
Current Opinion in Immunology | 1993 |
Type 2 cytokines and negative immune regulation in human infections
RL Modlin, TB Nutman |
Current Opinion in Immunology | 1993 |