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Citations to this article

In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma.
C L Karp, … , T B Nutman, D L Sacks
C L Karp, … , T B Nutman, D L Sacks
Published April 1, 1993
Citation Information: J Clin Invest. 1993;91(4):1644-1648. https://doi.org/10.1172/JCI116372.
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In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma.

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Abstract

Authors

C L Karp, S H el-Safi, T A Wynn, M M Satti, A M Kordofani, F A Hashim, M Hag-Ali, F A Neva, T B Nutman, D L Sacks

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Homeostatic regulation of T effector to Treg ratios in an area of seasonal malaria transmission
OC Finney, D Nwakanma, DJ Conway, M Walther, EM Riley
European Journal of Immunology 2009
KMP-11 DNA immunization significantly protects against L. donovani infection but requires exogenous IL-12 as an adjuvant for comparable protection against L. major
S Bhaumik, R Basu, S Sen, K Naskar, S Roy
Vaccine 2009
Complete protection against experimental visceral leishmaniasis with complete soluble antigen from attenuated Leishmania donovani promastigotes involves Th1-immunity and down-regulation of IL-10
SK Bhaumik, K Naskar, T De
European Journal of Immunology 2009
Leprosy coinfection with kala-azar
A Rijal, S Rijal, S Bhandari
International Journal of Dermatology 2009
Sub-optimal dose of Sodium Antimony Gluconate (SAG)-diperoxovanadate combination clears organ parasites from BALB/c mice infected with antimony resistant Leishmania donovani by expanding antileishmanial T-cell repertoire and increasing IFN-γ to IL-10 ratio
AK Haldar, S Banerjee, K Naskar, D Kalita, NS Islam, S Roy
Experimental Parasitology 2009
Immunoactivation and immunopathogeny during active visceral leishmaniasis
H Goto, MG Prianti
Revista do Instituto de Medicina Tropical de São Paulo 2009
Phagocyte-Pathogen Interactions: Macrophages and the Host Response to Infection
DG Russell, S Gordon
2009
IL-27 Regulates IL-10 and IL-17 from CD4 + Cells in Nonhealing Leishmania major Infection
CF Anderson, JS Stumhofer, CA Hunter, D Sacks
Journal of immunology (Baltimore, Md. : 1950) 2009
Immunization with the DNA-Encoding N-Terminal Domain of Proteophosphoglycan of Leishmania donovani Generates Th1-Type Immunoprotective Response against Experimental Visceral Leishmaniasis
M Samant, R Gupta, S Kumari, P Misra, P Khare, PK Kushawaha, AA Sahasrabuddhe, A Dube
Journal of immunology (Baltimore, Md. : 1950) 2009
IL-10: The Master Regulator of Immunity to Infection
KN Couper, DG Blount, EM Riley
Journal of immunology (Baltimore, Md. : 1950) 2008
A detrimental role for IgG and FcgammaR in Leishmania mexicana infection
LU Buxbaum
Immunologic Research 2008
Immunization with the cysteine proteinase Ldccys1 gene from Leishmania (Leishmania) chagasi and the recombinant Ldccys1 protein elicits protective immune responses in a murine model of visceral leishmaniasis
JH Ferreira, LG Gentil, SS Dias, CE Fedeli, S Katz, CL Barbiéri
Vaccine 2008
Could the lower frequency of CD8+CD18+CD45RO+ lymphocytes be biomarkers of human VL?
J Clarencio, CI de Oliveira, C Favali, O Medina, A Caldas, CH Costa, DL Costa, C Brodskyn, A Barral, M Barral-Netto
International Immunology 2008
Can type-1 responses against intracellular pathogens be T helper 2 cytokine dependent?
J Alexander, E McFarlane
Microbes and Infection 2008
Leishmania donovani: Role of CD2 on CD4+ T-cell function in Visceral Leishmaniasis
S Bimal, SK Singh, S Sinha, K Pandey, PK Sinha, A Ranjan, SK Bhattacharya, P Das
Experimental Parasitology 2008
Macrophage and T-Cell Gene Expression in a Model of Early Infection with the Protozoan Leishmania chagasi
NA Ettinger, ME Wilson, G Matlashewski
PLoS neglected tropical diseases 2008
Kinesin Motor Domain of Leishmania donovani as a Future Vaccine Candidate
A Dey, P Sharma, NS Redhu, S Singh
Clinical and vaccine immunology : CVI 2008
Immunological and Genetic Evidence for a Crucial Role of IL-10 in Cutaneous Lesions in Humans Infected with Leishmania braziliensis
A Salhi, V Rodrigues, F Santoro, H Dessein, A Romano, LR Castellano, M Sertorio, S Rafati, C Chevillard, A Prata, A Alcaïs, L Argiro, A Dessein
Journal of immunology (Baltimore, Md. : 1950) 2008
Interleukin-10 and the pathogenesis of human visceral leishmaniasis
S Nylén, D Sacks
Trends in Immunology 2007
Atypical cutaneous leishmaniasis cases display elevated antigen-induced interleukin-10
B Rodriguez, R Beatty, A Belli, A Barreto, X Palacios, F Marin, E Harris
Parasite Immunology 2007
Evaluation of transformation growth factor β1, interleukin-10, and interferon-γ in male symptomatic and asymptomatic dogs naturally infected by Leishmania (Leishmania) chagasi
AP Corrêa, AC Dossi, RO Vasconcelos, DP Munari, VM de Lima
Veterinary Parasitology 2007
Immunogenicity of the P-8 amastigote antigen in the experimental model of canine visceral leishmaniasis
E Carrillo, S Ahmed, K Goldsmith-Pestana, J Nieto, Y Osorio, B Travi, J Moreno, D McMahon-Pratt
Vaccine 2007
Analysis of the cytokine profile in spleen cells from dogs naturally infected by Leishmania chagasi
RS Lage, GC Oliveira, SU Busek, LL Guerra, RC Giunchetti, R Corrêa-Oliveira, AB Reis
Veterinary Immunology and Immunopathology 2007
Leishmania infantum: Mixed T-helper-1/T-helper-2 immune response in experimentally infected BALB/c mice
N Rolão, S Cortes, S Gomes-Pereira, L Campino
Experimental Parasitology 2007
Splenic accumulation of IL-10 mRNA in T cells distinct from CD4 + CD25 + (Foxp3) regulatory T cells in human visceral leishmaniasis
S Nylén, R Maurya, L Eidsmo, KD Manandhar, S Sundar, D Sacks
Journal of Experimental Medicine 2007
CD4 + CD25 − Foxp3 − Th1 cells are the source of IL-10–mediated immune suppression in chronic cutaneous leishmaniasis
CF Anderson, M Oukka, VJ Kuchroo, D Sacks
Journal of Experimental Medicine 2007
Monocyte subpopulations and their differentiation patterns during infection
D Strauss-Ayali, SM Conrad, DM Mosser
Journal of leukocyte biology 2007
Splenic immune responses during canine visceral leishmaniasis
D Strauss-Ayali, G Baneth, CL Jaffe
Veterinary Research 2007
IL-10- and TGF-β-Mediated Susceptibility in Kala-azar and Post-kala-azar Dermal Leishmaniasis: The Significance of Amphotericin B in the Control of Leishmania donovani Infection in India
S Saha, S Mondal, R Ravindran, S Bhowmick, D Modak, S Mallick, M Rahman, S Kar, R Goswami, SK Guha, N Pramanik, B Saha, N Ali
Journal of immunology (Baltimore, Md. : 1950) 2007
Hybrid Cell Vaccination Resolves Leishmania donovani Infection by Eliciting a Strong CD8 + Cytotoxic T-Lymphocyte Response with Concomitant Suppression of Interleukin-10 (IL-10) but Not IL-4 or IL-13
R Basu, S Bhaumik, AK Haldar, K Naskar, T De, SK Dana, P Walden, S Roy
Infection and immunity 2007
Activation of the MAPK, ERK, following Leishmania amazonensis Infection of Macrophages
Z Yang, DM Mosser, X Zhang
Journal of immunology (Baltimore, Md. : 1950) 2007
Reduced nitric oxide synthase 2 (NOS2) promoter activity in the Syrian hamster renders the animal functionally deficient in NOS2 activity and unable to control an intracellular pathogen
LE Perez, B Chandrasekar, OA Saldarriaga, W Zhao, LT Arteaga, BL Travi, PC Melby
Journal of immunology (Baltimore, Md. : 1950) 2006
Distinct roles for IL-6 and IL-12p40 in mediating protection againstLeishmania donovani and the expansion of IL-10+ CD4+ T cells
S Stäger, A Maroof, S Zubairi, SL Sanos, M Kopf, PM Kaye
European Journal of Immunology 2006
Approach to the Patient with HIV and Coinfecting Tropical Infectious Diseases
KARP CL, COLEBUNDERS R
2006
Mixed inflammatory/regulatory cytokine profile marked by simultaneous raise of interferon-? and interleukin-10 and low frequency of tumour necrosis factor-?+monocytes are hallmarks of active human visceral Leishmaniasis due to Leishmania chagasi infection
V Peruhype-Magalhães, OA Martins-Filho, A Prata, LD Silva, A Rabello, A Teixeira-Carvalho, RM Figueiredo, SF Guimarães-Carvalho, TC Ferrari, JV Weyenbergh, R Correa-Oliveira
Clinical & Experimental Immunology 2006
Genome-wide scan for visceral leishmaniasis susceptibility genes in Brazil
SE Jamieson, EN Miller, CS Peacock, M Fakiola, ME Wilson, A Bales-Holst, MA Shaw, F Silveira, JJ Shaw, SM Jeronimo, JM Blackwell
Genes and Immunity 2006
Multiplex analysis of circulating cytokines in the sera of patients with different clinical forms of visceral leishmaniasis
KM Kurkjian, AJ Mahmutovic, KL Kellar, R Haque, C Bern, WE Secor
Cytometry Part A 2006
The two faces of interleukin 10 in human infectious diseases
JL Mege, S Meghari, A Honstettre, C Capo, D Raoult
The Lancet Infectious Diseases 2006
Surrogate markers of immunity to Leishmania major in leishmanin skin test negative individuals from an endemic area re-visited
S Nylén, A Khamesipour, A Mohammadi, R Jafari-Shakib, L Eidsmo, S Noazin, F Modabber, H Akuffo
Vaccine 2006
Immune privilege in sites of chronic infection: Leishmania and regulatory T cells
N Peters, D Sacks
Immunological Reviews 2006
Balancing immunity and pathology in visceral leishmaniasis
AC Stanley, CR Engwerda
Immunology and Cell Biology 2006
Elevated levels of interferon-gamma, interleukin-10, and interleukin-6 during active disease in Indian kala azar
NA Ansari, S Saluja, P Salotra
Clinical Immunology 2006
Real-Time Reverse Transcription-PCR Quantification of Cytokine mRNA Expression in Golden Syrian Hamster Infected with Leishmania infantum and Treated with a New Amphotericin B Formulation
SR Iñiguez, MA Dea-Ayuela, JA Sanchez-Brunete, JJ Torrado, JM Alunda, F Bolas-Fernández
Antimicrobial agents and chemotherapy 2006
Antagonizing deactivating cytokines to enhance host defense and chemotherapy in experimental visceral leishmaniasis
HW Murray, KC Flanders, DD Donaldson, JP Sypek, PJ Gotwals, J Liu, X Ma
Infection and immunity 2005
Interleukin-12 augments a Th1-type immune response manifested as lymphocyte proliferation and interferon gamma production in Leishmania infantum-infected dogs
D Strauss-Ayali, G Baneth, S Shor, F Okano, CL Jaffe
International Journal for Parasitology 2005
T cell subset and cytokine profiles in human visceral leishmaniasis during active and asymptomatic or sub-clinical infection with Leishmania donovani
A Hailu, D Baarle, GJ Knol, N Berhe, F Miedema, PA Kager
Clinical Immunology 2005
Immunopathogenesis of infection with the visceralizing Leishmania species
ME Wilson, SM Jeronimo, RD Pearson
Microbial Pathogenesis 2005
Interleukin 10 receptor blockade—pentavalent antimony treatment in experimental visceral leishmaniasis
HW Murray
Acta Tropica 2005
Semi-quantitative analysis of cytokine expression in asymptomatic canine leishmaniasis
C Chamizo, J Moreno, J Alvar
Veterinary Immunology and Immunopathology 2005
Leishmania donovani: identification of novel vaccine candidates using human reactive sera and cell lines
SK Arora, NS Pal, S Mujtaba
Experimental Parasitology 2005
Respuesta immune a la leishmaniasis: algo más que linfocitos T
DL Bonilla-Escobar
Piel 2005
A role for IgG immune complexes during infection with the intracellular pathogen Leishmania
SA Miles, SM Conrad, RG Alves, SM Jeronimo, DM Mosser
Journal of Experimental Medicine 2005
Current understandings on the immunology of leishmaniasis and recent developments in prevention and treatment
MT Roberts
British Medical Bulletin 2005
Kinetoplastid Membrane Protein-11 DNA Vaccination Induces Complete Protection against Both Pentavalent Antimonial-Sensitive and -Resistant Strains of Leishmania donovani That Correlates with Inducible Nitric Oxide Synthase Activity and IL-4 Generation: Evidence for Mixed Th1- and Th2-Like Responses in Visceral Leishmaniasis
R Basu, S Bhaumik, JM Basu, K Naskar, T De, S Roy
Journal of immunology (Baltimore, Md. : 1950) 2005
Nonhealing Infection despite Th1 Polarization Produced by a Strain of Leishmania major in C57BL/6 Mice
CF Anderson, S Mendez, DL Sacks
Journal of immunology (Baltimore, Md. : 1950) 2005
Does the Leishmania major paradigm of pathogenesis and protection hold for New World cutaneous leishmaniases or the visceral disease?
D McMahon-Pratt, J Alexander
Immunological Reviews 2004
Re-examination of the immunosuppressive mechanisms mediating non-cure of Leishmania infection in mice
D Sacks, C Anderson
Immunological Reviews 2004
Progress in the treatment of a neglected infectious disease: visceral leishmaniasis
HW Murray
Expert Review of Anti-infective Therapy 2004
Vaccination withLeishmaniasoluble antigen and immunostimulatory oligodeoxynucleotides induces specific immunity and protection againstLeishmania donovaniinfection
P Tewary, J Mehta, B Sukumaran, R Madhubala
FEMS Immunology & Medical Microbiology 2004
Immunostimulatory oligodeoxynucleotides are potent enhancers of protective immunity in mice immunized with recombinant ORFF leishmanial antigen
P Tewary, B Sukumaran, S Saxena, R Madhubala
Vaccine 2004
Characterization of immunoglobulin G and its subclass response to Indian kala-azar infection before and after chemotherapy
R Ravindran, K Anam, BC Bairagi, B Saha, N Pramanik, SK Guha, RP Goswami, D Banerjee, N Ali
Infection and immunity 2004
Immunity and immunosuppression in experimental visceral leishmaniasis
H Goto, JA Lindoso
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] 2004
Inbred Strains Derived from Feral Mice Reveal New Pathogenic Mechanisms of Experimental Leishmaniasis Due to Leishmania major
BE Babay, H Louzir, C Kebaïer, S Boubaker, K Dellagi, PA Cazenave
Infection and immunity 2004
Vaccination with DNA encoding ORFF antigen confers protective immunity in mice infected with Leishmania donovani
B Sukumaran, P Tewary, S Saxena, R Madhubala
Vaccine 2003
The role of CD4+CD25+ regulatory T cells in Leishmania infection
Y Belkaid
Expert Opinion on Biological Therapy 2003
The site of cutaneous infection influences the immunological response and clinical outcome of hamsters infected with Leishmania panamensis
Y Osorio, PC Melby, C Pirmez, B Chandrasekar, N Guarin, BL Travi
Parasite Immunology 2003
Development of a leishmaniasis vaccine: the importance of MPL
SG Reed, RN Coler, A Campos-Neto
Expert Review of Vaccines 2003
Intradermal infection model for pathogenesis and vaccine studies of murine visceral leishmaniasis
S Ahmed, M Colmenares, L Soong, K Goldsmith-Pestana, L Munstermann, R Molina, D McMahon-Pratt
Infection and immunity 2003
The Relative Contribution of IL-4 Receptor Signaling and IL-10 to Susceptibility to Leishmania major
N Noben-Trauth, R Lira, H Nagase, WE Paul, DL Sacks
Journal of immunology (Baltimore, Md. : 1950) 2003
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
Y Belkaid, CA Piccirillo, S Mendez, EM Shevach, DL Sacks
Nature 2002
IL-15 in human visceral leishmaniasis caused by Leishmania infantum
S Milano, GD Bella, P D'Agostino, C Barbera, R Caruso, ML Rosa, V Ferlazzo, G Vitale, CL Russa, G Gambino, N Chifari, S Mansueto, E Cillari
Clinical & Experimental Immunology 2002
Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy
HW Murray, CM Lu, S Mauze, S Freeman, AL Moreira, G Kaplan, RL Coffman
Infection and immunity 2002
IL-10 leads to a higher parasite persistence in a resistant mouse model of Leishmania major infection
AV da Costa, M Huerre, M Delacre, C Auriault, JM Costa, C Verwaerde
Parasitology International 2002
The immunology of susceptibility and resistance to Leishmania major in mice
D Sacks, N Noben-Trauth
Nature Reviews Immunology 2002
Leishmania
JP Farrell
2002
Gender Is a Major Determinant of the Clinical Evolution and Immune Response in Hamsters Infected with Leishmania spp
BL Travi, Y Osorio, PC Melby, B Chandrasekar, L Arteaga, NG Saravia
Infection and immunity 2002
Characterization of Leishmania donovani Antigens Encapsulated in Liposomes That Induce Protective Immunity in BALB/c Mice
F Afrin, R Rajesh, K Anam, M Gopinath, S Pal, N Ali
Infection and immunity 2002
Cytokine responses to mitogen and Schistosoma haematobium antigens are different in children with distinct infection histories
JT Scott, CR Turner, F Mutapi, ME Woolhouse, PD Ndhlovu, P Hagan
Parasite Immunology 2001
Cytokine Gene Expression in Healing and Non-Healing Cases of Cutaneous Leishmaniasis in Response to In vitro Stimulation with Recombinant gp63 Using Semi-Quantitative RT-PCR
GR Habibi, A Khamesipour, WR McMaster, F Mahboudi
Scandinavian Journal of Immunology 2001
iNOS expression by activated neutrophils from patients with sepsis
Y Tsukahara, T Morisaki, M Kojima, A Uchiyama, M Tanaka
ANZ Journal of Surgery 2001
Clinical and experimental advances in treatment of visceral leishmaniasis
HW Murray
Antimicrobial agents and chemotherapy 2001
Interleukin-13 in Iranian patients with visceral leishmaniasis: relationship to other Th2 and Th1 cytokines
Z Babaloo, PM Kaye, MB Eslami
Transactions of the Royal Society of Tropical Medicine and Hygiene 2001
Interleukin-10 and the interleukin-10 receptor
KW Moore, RW Malefyt, RL Coffman, A O'Garra
Annual Review of Immunology 2001
Immunization with A2 protein results in a mixed Th1/Th2 and a humoral response which protects mice against Leishmania donovani infections
A Ghosh, WW Zhang, G Matlashewski
Vaccine 2001
The dual role of CTLA-4 in Leishmania infection
NA Gomes, GA DosReis
Trends in Parasitology 2001
Immunology of Infectious Diseases
SH Kaufmann, A Sher, R Ahmed
2001
The Hamster as a Model of Human Visceral Leishmaniasis: Progressive Disease and Impaired Generation of Nitric Oxide in the Face of a Prominent Th1-Like Cytokine Response
PC Melby, B Chandrasekar, W Zhao, JE Coe
Journal of immunology (Baltimore, Md. : 1950) 2001
Detection of specific antibody isotypes and subtypes before and after treatment of American visceral leishmaniasis
VL da Matta, S Hoshino-Shimizu, R Dietze, CE Corbett
Journal of Clinical Laboratory Analysis 2000
Endogenous IL-4 is necessary for effective drug therapy against visceral leishmaniasis
J Alexander, KC Carter, N Al-Fasi, A Satoskar, F Brombacher
European Journal of Immunology 2000
Resistance/susceptibility to Echinococcus multilocularis infection and cytokine profile in humans. I. Comparison of patients with progressive and abortive lesions
V Godot, S Harraga, I Beurton, M Deschaseaux, E Sarciron, B Gottstein, DA Vuitton
Clinical & Experimental Immunology 2000
Treatment of visceral leishmaniasis (kala-azar): A decade of progress and future approaches
HW Murray
International Journal of Infectious Diseases 2000
Role of CD8+ T cells in endogenous interleukin-10 secretion associated with visceral leishmaniasis
BJ Holaday
Memórias do Instituto Oswaldo Cruz 2000
Early in vitro priming of distinct Th cell subsets determines polarized growth of visceralizing Leishmania in macrophages
NA Gomes, V Barreto-de-Souza, GA DosReis
International Immunology 2000
A Novel Leishmania infantum Recombinant Antigen Which Elicits Interleukin 10 Production by Peripheral Blood Mononuclear Cells of Patients with Visceral Leishmaniasis
TR Kozel, I Suffia, B Ferrua, X Stien, B Mograbi, P Marty, D Rousseau, K Fragaki, J Kubar
Infection and immunity 2000
Mitogenesis in glioblastoma multiforme cell lines: a role for NGF and its TrkA receptors
H S Singer, B Hansen, D Martinie, C L Karp
Journal of Neuro-Oncology 2000
Detection of specific antibody isotypes and subtypes before and after treatment of American visceral leishmaniasis
da Matta VL, Hoshino\u2010Shimizu S, Dietze R, Corbett CE
Journal of Clinical Laboratory Analysis 2000
Les leishmanioses: un modèle d'étude des interactions hôte-parasite; implications pour la maladie humaine
H Louzir, K Dellagi
Annales de l'Institut Pasteur/Actualités 1999
Leishmaniasis
BL Herwaldt
The Lancet 1999
Receptor mediated subversion of macrophage cytokine production by intracellular pathogens
DM Mosser, L arpt
Current Opinion in Immunology 1999
Leishmanin skin test lymphoproliferative responses and cytokine production after symptomatic or asymptomatic Leishmania major infection in Tunisia
A Sassi, H Louzir, AB Salah, M Mokni, AB Osman, K Dellagi
Clinical & Experimental Immunology 1999
Leishmania-specific T cells expressing interferon-gamma (IFN-gamma) and IL-10 upon activation are expanded in individuals cured of visceral leishmaniasis
K Kemp, M Kemp, A Kharazmi, A Ismail, JA Kurtzhals, L Hviid, TG Theander
Clinical & Experimental Immunology 1999
Differential decline in Leishmania membrane antigen-specific immunoglobulin G (IgG), IgM, IgE, and IgG subclass antibodies in Indian kala-azar patients after chemotherapy
K Anam, F Afrin, D Banerjee, N Pramanik, SK Guha, RP Goswami, SK Saha, N Ali
Infection and immunity 1999
T-cell response in human leishmaniasis
A Kharazmi, K Kemp, A Ismail, S Gasim, A Gaafar, JA Kurtzhals, AM Hassan, TG Theander, M Kemp
Immunology Letters 1999
Interferon-γ- and Tumour Necrosis Factor-α-Producing Cells in Humans who are Immune to Cutaneous Leishmaniasis: IFN-γ and TNF-α in Leishmaniasis
KEMP, THEANDER, HVIID, GARFAR, KHARAZMI, KEMP
Scandinavian Journal of Immunology 1999
Leishmania–HIV Interaction: Immunopathogenic Mechanisms
D Wolday, N Berhe, H Akuffo, S Britton
Parasitology Today 1999
Immunotherapy for Visceral Leishmaniasis: Ability of Factors Produced during Anti-leishmania Responses of Skin Test Positive Adults to Inhibit Peripheral Blood Mononuclear Cell Activities Associated with Visceral Leishmaniasis
BJ Holaday
Memórias do Instituto Oswaldo Cruz 1999
Differential Decline in Leishmania Membrane Antigen-Specific Immunoglobulin G (IgG), IgM, IgE, and IgG Subclass Antibodies in Indian Kala-Azar Patients after Chemotherapy
SH Kaufmann, K Anam, F Afrin, D Banerjee, N Pramanik, SK Guha, RP Goswami, SK Saha, N Ali
Infection and immunity 1999
Leishmania species: models of intracellular parasitism
J Alexander, AR Satoskar, DG Russell
Journal of cell science 1999
Immunoglobulin Subclass Distribution and Diagnostic Value of Leishmania donovani Antigen-Specific Immunoglobulin G3 in Indian Kala-Azar Patients
K Anam, F Afrin, D Banerjee, N Pramanik, SK Guha, RP Goswami, PN Gupta, SK Saha, N Ali
Clinical and diagnostic laboratory immunology 1999
Distribution of IgG subclasses in antimonial unresponsive Indian kala-azar patients
M Chatterjee, K Basu, D Basu, D Bannerjee, N Pramanik, SK Guha, RP Goswami, SK Saha, C Mandal
Clinical & Experimental Immunology 1998
High levels of plasma IL-10 and expression of IL-10 by keratinocytes during visceral leishmaniasis predict subsequent development of post-kala-azar dermal leishmaniasis
S Gasim, AM Elhassan, EA Khalil, A Ismail, AM Kadaru, A Kharazmi, TG Theander
Clinical & Experimental Immunology 1998
Mapping of specific and promiscuous HLA-DR-restricted T-cell epitopes on the Plasmodium falciparum 27-kilodalton sexual stage-specific antigen
CE Contreras, IN Ploton, RF Siliciano, CL Karp, R Viscidi, N Kumar
Infection and immunity 1998
Decreased mRNA Expression of Several Basement Membrane Components in Basal Cell Carcinoma
A Chopra, B Maitra, NJ Korman
Journal of Investigative Dermatology 1998
Human_Leishmaniasis@cytokines.bahia.br
M Barral-Netto, C Brodskyn, EM Carvalho, A Barral
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] 1998
Presence of Circulating Levels of Interferon-g, Interleukin-10 and Tumor Necrosis Factor-a in Patients with Visceral Leishmaniasis
IM de MEDEIROS, A CASTELO, R SALOMÃO
Revista do Instituto de Medicina Tropical de São Paulo 1998
Cytokine profile and pathology in human leishmaniasis
A Ribeiro-de-Jesus, RP Almeida, H Lessa, O Bacellar, EM Carvalho
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] 1998
Regional Differences in the Cellular Immune Response to Experimental Cutaneous or Visceral Infection with Leishmania donovani
PC Melby, YZ Yang, J Cheng, W Zhao
Infection and immunity 1998
Cloning of Syrian Hamster ( Mesocricetus auratus ) Cytokine cDNAs and Analysis of Cytokine mRNA Expression in Experimental Visceral Leishmaniasis
PC Melby, VV Tryon, B Chandrasekar, GL Freeman
Infection and immunity 1998
Importance of Interleukin-10 in Genetic Susceptibility of Mice to Coccidioides immitis
TR Kozel, J Fierer, L Walls, L Eckmann, T Yamamoto, TN Kirkland
Infection and immunity 1998
Interleukin-10 and interleukin-4 inhibit intracellular killing ofLeishmania infantum andLeishmania major by human macrophages by decreasing nitric oxide generation
I Vouldoukis, PA Bécherel, V Riveros-Moreno, M Arock, OD Silva, P Debré, D Mazier, MD Mossalayi
European Journal of Immunology 1997
Adjuvanticity and protective immunity elicited by Leishmania donovani antigens encapsulated in positively charged liposomes
F Afrin, N Ali
Infection and immunity 1997
Association of Leishmania heat shock protein 83 antigen and immunoglobulin G4 antibody titers in Brazilian patients with diffuse cutaneous leishmaniasis
YA Skeiky, DR Benson, JL Costa, R Badaro, SG Reed
Infection and immunity 1997
T helper type 2 like cytokine responses to peptides from P0 and P2 myelin proteins during the recovery phase of Guillain-Barré syndrome
C Dahle, C Ekerfelt, M Vrethem, M Samuelsson, J Ernerudh
Journal of the Neurological Sciences 1997
Regulator and effector functions of T-cell subsets in human Leishmanaia infections
M Kemp
APMIS 1997
Zinc-controlled Th1/Th2 switch significantly determines development of diseases
JE Sprietsma
Medical Hypotheses 1997
Behavior of  Visceral Leishmania donovani in an Experimentally Induced T Helper Cell 2 (Th2)-Associated Response Model
HW Murray, J Hariprashad, RL Coffman
Journal of Experimental Medicine 1997
Cell-Mediated Immune System Regulation in Periodontal Diseases
A Mathur, BS Michalowicz
Critical Reviews in Oral Biology & Medicine 1997
Asymptomatic Leishmania chagasi Infection in Relatives and Neighbors of Patients with Visceral Leishmaniasis
AD Júnior, SR Costa, AB Barbosa, ML la Orge, EM Carvalho
Memórias do Instituto Oswaldo Cruz 1997
Evidence of a T helper type 2 activation in human schistosomiasis
MI Araújo, AR de Jesus, O Bacellar, E Sabin, E Pearce, EM Carvalho
European Journal of Immunology 1996
In situ expression of interleukin-10 and interleukin-12 in active human cutaneous leishmaniasis
PC Melby, F Andrade-Narvaez, BJ Darnell, G Valencia-Pacheco
FEMS Immunology & Medical Microbiology 1996
Early commitment to the eosinophil lineage by cultured human peripheral blood CD34+ cells: Messenger RNA analysis
M Shalit, S Sekhsaria, F Li, S Mauhorter, S Mahanti, HL Malech
Journal of Allergy and Clinical Immunology 1996
Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases
DR Lucey, M Clerici, GM Shearer
Clinical microbiology reviews 1996
Evidence for a predominant proinflammatory conjunctival cytokine response in individuals with trachoma
L Bobo, N Novak, H Mkocha, S Vitale, S West, TC Quinn
Infection and immunity 1996
Cross-modulation by transforming growth factor beta in human tuberculosis: suppression of antigen-driven blastogenesis and interferon gamma production
CS Hirsch, R Hussain, Z Toossi, G Dawood, F Shahid, JJ Ellner
Proceedings of the National Academy of Sciences 1996
Lipophosphoglycan from Leishmania suppresses agonist-induced interleukin 1 beta gene expression in human monocytes via a unique promoter sequence
DE Hatzigeorgiou, J Geng, B Zhu, Y Zhang, K Liu, WN Rom, MJ Fenton, SJ Turco, JL Ho
Proceedings of the National Academy of Sciences 1996
Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice
L Carrera, RT Gazzinelli, R Badolato, S Hieny, W Muller, R Kuhn, DL Sacks
Journal of Experimental Medicine 1996
VISCERAL LEISHMANIASIS
ME Wilson, JA Streit
Gastroenterology Clinics of North America 1996
The contrasting roles of CD4+ T cells in intracellular infections in humans: leishmaniasis as an example
M Kemp, TG Theander, A Kharazmi
Immunology Today 1996
Lipophosphoglycan from Leishmania suppresses agonist-induced interleukin 1  gene expression in human monocytes via a unique promoter sequence
DE Hatzigeorgiou, J Geng, B Zhu, Y Zhang, K Liu, WN Rom, MJ Fenton, SJ Turco, JL Ho
Proceedings of the National Academy of Sciences 1996
Interferon β-1b effects on cytokine mRNA in peripheral mononuclear cells in multiple sclerosis
PV Byskosh, AT Reder
Multiple sclerosis (Houndmills, Basingstoke, England) 1996
Mechanism of Suppression of Cell-Mediated Immunity by Measles Virus
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Science 1996
Dichotomy of the T cell response to Leishmania antigens in patients suffering from cutaneous leishmaniasis; absence or scarcity of Th1 activity is associated with severe infections
A Gaafar, A Kharazmi, A Ismail, M Kemp, A Hey, CB Christensen, M Dafalla, AY Kadaro, AM Hassan, TG Theander
Clinical & Experimental Immunology 1995
CD28 activation promotes Th2 subset differentiation by human CD4+ cells
CL King, RJ Stupi, N Craighead, CH June, G Thyphronitis
European Journal of Immunology 1995
Switch from a type 2 to a type 1 T helper cell response and cure of established Leishmania major infection in mice is induced by combined therapy with interleukin 12 and Pentostam
GS Nabors, LC Afonso, JP Farrell, P Scott
Proceedings of the National Academy of Sciences 1995
Human T-cell activation by 14- and 18-kilodalton nuclear proteins of Leishmania infantum
I Suffia, JF Quaranta, MC Eulalio, B Ferrua, P Marty, YL Fichoux, J Kubar
Infection and immunity 1995
Allergen-stimulated interleukin-4 and interferon-gamma production in primary culture: responses of subjects with allergic rhinitis and normal controls
M Imada, FE Simons, FT Jay, KT Hayglass
Immunology 1995
Interleukin 12 is effective treatment for an established systemic intracellular infection: experimental visceral leishmaniasis
HW Murray, J Hariprashad
Journal of Experimental Medicine 1995
Disruption of the murine interleukin-4 gene inhibits disease progression during Leishmania mexicana infection but does not increase control of Leishmania donovani infection
A Satoskar, H Bluethmann, J Alexander
Infection and immunity 1995
Interleukin-10
JE de Vries, R de Waal Malefyt
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Dichotomy of the T cell response to Leishmania antigens in patients suffering from cutaneous leishmaniasis; absence or scarcity of Th1 activity is associated with severe infections.
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Clinical & Experimental Immunology 1995
Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus
M Clerici, TA Wynn, JA Berzofsky, SP Blatt, CW Hendrix, A Sher, RL Coffman, GM Shearer
Journal of Clinical Investigation 1994
Cytokines in the treatment of leishmaniasis: From studies of immunopathology to patient therapy
JL Ho, R Badaro, D Hatzigeorgiou, SG Reed, WD Johnson
Biotherapy 1994
Dichotomy in the human CD4+T-cell response toLeishmaniaparasites
MI Kemp, JØ Kurtzhals, AR Kharazmi, TH Theander
APMIS 1994
T lymphocytes derived from skin lesions of patients with psoriasis vulgaris express a novel cytokine pattern that is distinct from that of T helper type 1 and T helper type 2 cells
S Vollmer, A Menssen, P Trommler, D Schendel, JC Prinz
European Journal of Immunology 1994
Increased expression of proinflammatory cytokines in chronic lesions of human cutaneous leishmaniasis
PC Melby, FJ Andrade-Narvaez, BJ Darnell, G Valencia-Pacheco, VV Tryon, A Palomo-Cetina
Infection and immunity 1994
Th1 and Th2 cell-associated cytokines in experimental visceral leishmaniasis
GD Miralles, MY Stoeckle, DF McDermott, FD Finkelman, HW Murray
Infection and immunity 1994
Divergent T-cell cytokine patterns in inflammatory arthritis
AK Simon, E Seipelt, J Sieper
Proceedings of the National Academy of Sciences 1994
Limiting dilution analysis of antigen stimulated IL-4 and IFN-γ production in human mononuclear cell populations
Y Li, WP Stefura, FE Simons, FT Jay, KT Hayglass
Journal of Immunological Methods 1994
The Th1–Th2 hypothesis of HIV infection: new insights
M Clerici, GM Shearer
Immunology Today 1994
Interleukin 12 and the regulation of CD4+ T-cell subset responses during murine Leishmaniasis
FP Heinzel
Parasitology Today 1994
CD23 and IgE expression during the human immune response to cutaneous leishmaniasis : Possible role in monocyte activation
I Vouldoukis, F Issaly, C Fourcade, N Paul-Eugène, M Arock, JP Kolb, OA da Silva, L Monjour, H Poinsot, Y Tselentis, B Dugas, P Debré, MD Mossalayi
Research in Immunology 1994
Leishmania infantum Tropism: Strain genotype or host immune status?
L Gradoni, M Gramiccia
Parasitology Today 1994
Cytokines and T Cell Switching
E Gemmell, GJ Seymour
Critical Reviews in Oral Biology & Medicine 1994
Cytokines in the Treatment of Infectious Diseases
BJ Kullberg, JW Meer
1994
Lack of Evidence for the Dichotomy of T H 1 and T H 2 Predominance in HIV-Infected Individuals
C Graziosi, G Pantaleo, KR Gantt, JP Fortin, JF Demarest, OJ Cohen, RP Sékaly, AS Fauci
Science 1994
Cytokine control of parasite-specific anergy in human lymphatic filariasis. Preferential induction of a regulatory T helper type 2 lymphocyte subset
CL King, S Mahanty, V Kumaraswami, JS Abrams, J Regunathan, K Jayaraman, EA Ottesen, TB Nutman
Journal of Clinical Investigation 1993
Potential role for interleukin-10 in the immunosuppression associated with kala azar
BJ Holaday, MM Pompeu, S Jeronimo, MJ Texeira, AA Sousa, AW Vasconcelos, RD Pearson, JS Abrams, RM Locksley
Journal of Clinical Investigation 1993
T-cell and cytokine responses in leishmaniasis
SG Reed, P Scott
Current Opinion in Immunology 1993
Type 2 cytokines and negative immune regulation in human infections
RL Modlin, TB Nutman
Current Opinion in Immunology 1993

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