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Metabolism of triglyceride-rich lipoproteins during alimentary lipemia.

F Karpe, … , L A Carlson, A Hamsten

F Karpe, … , L A Carlson, A Hamsten

Published March 1, 1993
Citation Information: J Clin Invest. 1993;91(3):748-758. https://doi.org/10.1172/JCI116293.

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Postprandial triglyceride levels rather than fat distribution may reflect early signs of disturbed fat metabolism in Iraqi immigrants. Stenkula KG, Klemendz LE, Fryklund C, Wierup N, Alsalim W, Landin-Olsson M, Trinh L, Månsson S, Bennet L	Lipids in Health and Disease	2022
Apolipoprotein E content of VLDL limits LPL-mediated triglyceride hydrolysis. Whitacre BE, Howles P, Street S, Morris J, Swertfeger D, Davidson WS	Journal of lipid research	2021
Reduced Reverse Cholesterol Transport Efficacy in Healthy Men with Undesirable Postprandial Triglyceride Response A Motte, J Gall, JE Salem, E Dasque, M Lebot, E Frisdal, S Galier, EF Villard, E Bouaziz-Amar, JM Lacorte, B Charbit, WL Goff, P Lesnik, M Guerin	Biomolecules	2020
Oxylipins in triglyceride-rich lipoproteins of dyslipidemic subjects promote endothelial inflammation following a high fat meal A Rajamani, K Borkowski, S Akre, A Fernandez, JW Newman, SI Simon, AG Passerini	Scientific Reports	2019
Effects of Dietary Protein and Fat Content on Intrahepatocellular and Intramyocellular Lipids during a 6-Day Hypercaloric, High Sucrose Diet: A Randomized Controlled Trial in Normal Weight Healthy Subjects A Surowska, P Jegatheesan, V Campos, AS Marques, L Egli, J Cros, R Rosset, V Lecoultre, R Kreis, C Boesch, B Pouymayou, P Schneiter, L Tappy	Nutrients	2019
Large triglyceride-rich lipoproteins in hypertriglyceridemia are associated with the severity of acute pancreatitis in experimental mice Y Zhang, W He, C He, J Wan, X Lin, , L Li, X Li, X Yang, B Yu, X Xian, Y Zhu, Y Wang, G Liu, N Lu	Cell Death and Disease	2019
Four nights of sleep restriction suppress the postprandial lipemic response and decrease satiety KM Ness, SM Strayer, NG Nahmod, MM Schade, AM Chang, GC Shearer, OM Buxton	Journal of lipid research	2019
Removal of Chylomicron Remnants from the Bloodstream is Delayed in Aged Subjects CG Vinagre, FR Freitas, CH de Mesquita, JC Vinagre, AC Mariani, R Kalil-Filho, RC Maranhão	Aging and disease	2018
Triglyceride is Significantly Increased in Remnant Lipoproteins After Food Intake and its Association with Lipoprotein Lipase in the Plasma K Nakajima, Y Tokita, A Tanaka		2018
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Triglyceride content in remnant lipoproteins is significantly increased after food intake and is associated with plasma lipoprotein lipase K Nakajima, Y Tokita, K Sakamaki, Y Shimomura, J Kobayashi, K Kamachi, A Tanaka, KL Stanhope, PJ Havel, T Wang, T Machida, M Murakami	Clinica chimica acta; international journal of clinical chemistry	2017
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Tracing the fate of dietary fatty acids: metabolic studies of postprandial lipaemia in human subjects B Fielding	Proceedings of the Nutrition Society	2011
Hypoglycemia: A Possible Link between Insulin Resistance, Metabolic Dyslipidemia, and Heart and Kidney Disease (the Cardiorenal Syndrome) M Ensling, W Steinmann, A Whaley-Connell	Cardiorenal Medicine	2011
Measurement of serum remnant-like lipoprotein particle-triglyceride (RLP-TG) and RLP-TG/total TG ratio using highly sensitive triglyceride assay reagent T Nakano, Y Tokita, T Nagamine, A Tanaka, M Okazaki, S Yatsuzuka, N Tamei, Y Shimomura, Y Ando, S Akamatsu, MQ Fujita, K Nakajima	Clinica Chimica Acta	2011
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Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation? L Hodson, SE McQuaid, SM Humphreys, R Milne, BA Fielding, KN Frayn, F Karpe	American journal of physiology. Endocrinology and metabolism	2010
Particle size of apoB-48 carrying lipoproteins in remnant lipoproteins isolated from postprandial plasma T Nakano, A Tanaka, M Okazaki, Y Tokita, T Nagamine, K Nakajima	Annals of Clinical Biochemistry	2010
Fatty Acids from Very Low-Density Lipoprotein Lipolysis Products Induce Lipid Droplet Accumulation in Human Monocytes LJ den Hartigh, JE Connolly-Rohrbach, S Fore, TR Huser, JC Rutledge	Journal of immunology (Baltimore, Md. : 1950)	2010
Beneficial effects of designed dietary fatty acid compositions on lipids in triacylglycerol-rich lipoproteins among Chinese patients with type 2 diabetes mellitus J Dai, YX Su, S Bartell, NA Le, WH Ling, YQ Liang, L Gao, HY Wu, E Veledar, V Vaccarino	Metabolism	2009
Differences in partitioning of meal fatty acids into blood lipid fractions: a comparison of linoleate, oleate, and palmitate L Hodson, SE McQuaid, F Karpe, KN Frayn, BA Fielding	American journal of physiology. Endocrinology and metabolism	2009
Oral fat load effects on inflammation and endothelial stress markers in healthy subjects G Derosa, I Ferrari, A DAngelo, SA Salvadeo, E Fogari, A Gravina, R Mereu, I Palumbo, P Maffioli, S Randazzo, AF Cicero	Heart and Vessels	2009
Modern Nutrition K LaPoint, M McIntosh	Handbook of Nutrition in the Aged, Fourth Edition	2008
The ApoC-I Content of VLDL Particles is Associated with Plaque Size in Persons with Carotid Atherosclerosis AT Notø, EB Mathiesen, J Brox, J Björkegren, JB Hansen	Lipids	2008
Postprandial chylomicrons and adipose tissue lipoprotein lipase are altered in type 2 diabetes independently of obesity and whole-body insulin resistance G Annuzzi, R Giacco, L Patti, LD Marino, CD Natale, G Costabile, M Marra, C Santangelo, R Masella, AA Rivellese	Nutrition, Metabolism and Cardiovascular Diseases	2008
Therapeutic Effects of Fibrates in Postprandial Lipemia GD Kolovou, PM Kostakou, KK Anagnostopoulou, DV Cokkinos	American Journal of Cardiovascular Drugs	2008
Respuesta posprandial de la apolipoproteína B-48 y del perfil lipídico en pacientes con diabetes mellitus tipo 2 JR Villodres, YP Molina, P Valdivielso, MJ Ariza, MÁ Chaparro, PG Santos	Clínica e Investigación en Arteriosclerosis	2008
Parallel activation of de novo lipogenesis and stearoyl-CoA desaturase activity after 3 d of high-carbohydrate feeding MF Chong, L Hodson, AS Bickerton, R Roberts, M Neville, F Karpe, KN Frayn, BA Fielding	The American journal of clinical nutrition	2008
Impact of testosterone treatment on postprandial triglyceride metabolism in elderly men with subnormal testosterone levels I Agledahl, JB Hansen, J Svartberg	Scandinavian Journal of Clinical & Laboratory Investigation	2008
Wild-Type Food in Health Promotion and Disease Prevention FD Meester, RR Watson		2008
The contribution of splanchnic fat to VLDL triglyceride is greater in insulin-resistant than insulin-sensitive men and women: studies in the postprandial state L Hodson, AS Bickerton, SE McQuaid, R Roberts, F Karpe, KN Frayn, BA Fielding	Diabetes	2007
Methodology for studying postprandial lipid metabolism D Lairon, J Lopez-Miranda, C Williams	European Journal of Clinical Nutrition	2007
Mechanisms of Disease: lessons from ethnicity in the role of triglyceride metabolism in ischemic heart disease IF Godsland, DG Johnston, N Chaturvedi	Nature Clinical Practice Endocrinology & Metabolism	2007
ApoB-100 carrying lipoprotein, but not apoB-48, is the major subset of proatherogenic remnant-like lipoprotein particles detected in plasma of sudden cardiac death cases K Nakajima, Y Nakajima, S Takeichi, MQ Fujita	Atherosclerosis	2007
Tissue-specific stable isotope measurements of postprandial lipid metabolism in familial combined hyperlipidaemia K Evans, GC Burdge, SA Wootton, JM Collins, ML Clark, GD Tan, F Karpe, KN Frayn	Atherosclerosis	2007
Correlation of serum IGF-I and IGFBP-1 and -3 to cardiovascular risk indicators and early carotid atherosclerosis in healthy middle-aged men S Boquist, G Ruotolo, C Skoglund-Andersson, R Tang, J Björkegren, MG Bond, U Faire, K Brismar, A Hamsten	Clinical Endocrinology	2007
Dietary fatty acids make a rapid and substantial contribution to VLDL-triacylglycerol in the fed state RB Heath, F Karpe, RW Milne, GC Burdge, SA Wootton, KN Frayn	American journal of physiology. Endocrinology and metabolism	2007
Preferential uptake of dietary Fatty acids in adipose tissue and muscle in the postprandial period AS Bickerton, R Roberts, BA Fielding, L Hodson, EE Blaak, AJ Wagenmakers, M Gilbert, F Karpe, KN Frayn	Diabetes	2006
Atorvastatin or fenofibrate on post-prandial lipaemia in type 2 diabetic patients with hyperlipidaemia C Iovine, S Lilli, A Gentile, L Patti, LD Marino, P Cipriano, G Riccardi, AA Rivellese	European Journal of Clinical Investigation	2006
Impact of postprandial lipaemia on low-density lipoprotein (LDL) size and oxidized LDL in patients with coronary artery disease M Granér, J Kahri, T Nakano, SJ Sarna, MS Nieminen, M Syvänne, MR Taskinen	European Journal of Clinical Investigation	2006
Dietary diacylglycerol in a typical meal suppresses postprandial increases in serum lipid levels compared with dietary triacylglycerol K Tomonobu, T Hase, I Tokimitsu	Nutrition	2006
Postprandial Lipemia and Remnant Lipoproteins JS Cohn	Clinics in Laboratory Medicine	2006
Delayed secretory pathway contributions to VLDL-triglycerides from plasma NEFA, diet, and de novo lipogenesis in humans A Vedala, W Wang, RA Neese, MP Christiansen, MK Hellerstein	Journal of lipid research	2006
Microsomal triglyceride transfer protein −493T variant reduces IDL plus LDL apoB production and the plasma concentration of large LDL particles B Lundahl, C Skoglund-Andersson, M Caslake, D Bedford, P Stewart, A Hamsten, CJ Packard, F Karpe	American journal of physiology. Endocrinology and metabolism	2006
Postprandial changes in LDL phenotypes in patients with myocardial infarction S Koba, F Tsunoda, T Hirano, Y Iso, H Suzuki, E Geshi, T Katagiri	European Journal of Clinical Investigation	2005
Remnant lipoproteins and atherosclerosis TB Twickler, GM Dallinga-Thie, MJ Chapman, JS Cohn	Current Atherosclerosis Reports	2005
Diurnal and acute patterns of postprandial apolipoprotein B-48 in VLDL, IDL, and LDL from normolipidemic humans H Campos, C Khoo, FM Sacks	Atherosclerosis	2005
Cell-mediated LDL oxidation: The impact of transition metals and transferrin AV Campenhout, E Heytens, CV Campenhout, AR Lagrou, B Manuel-y-Keenoy	Biochemical and Biophysical Research Communications	2005
The apolipoprotein CI content of triglyceride-rich lipoproteins independently predicts early atherosclerosis in healthy middle-aged men A Hamsten, A Silveira, S Boquist, R Tang, MG Bond, U Faire, J Björkegren	Journal of the American College of Cardiology	2005
Intestinal Lipoprotein Overproduction, a Newly Recognized Component of Insulin Resistance, Is Ameliorated by the Insulin Sensitizer Rosiglitazone: Studies in the Fructose-Fed Syrian Golden Hamster GF Lewis, K Uffelman, M Naples, L Szeto, M Haidari, K Adeli	Endocrinology	2005
Meal ingestion provokes entry of lipoproteins containing fat from the previous meal: possible metabolic implications KD Silva, JW Wright, CM Williams, JA Lovegrove	European Journal of Nutrition	2004
Association Between Small Dense Low-Density Lipoprotein and Postprandial Accumulation of Triglyceride-Rich Remnant-Like Particles in Normotriglyceridemic Patients With Myocardial Infarction F Tsunoda, S Koba, T Hirano, Y Ban, Y Iso, H Suzuki, E Geshi, T Katagiri	Circulation Journal	2004
Apolipoprotein B-48: comparison of fasting concentrations measured in normolipidaemic individuals using SDS–PAGE, immunoblotting and ELISA KG Jackson, CM Williams	Atherosclerosis	2004
Self-monitoring of plasma triglyceride levels to evaluate postprandial response to different nutrients C Iovine, A Gentile, A Hattemer, D Pacioni, G Riccardi, AA Rivellese	Metabolism	2004
A randomized study comparing the effects of a low-carbohydrate diet and a conventional diet on lipoprotein subfractions and C-reactive protein levels in patients with severe obesity P Seshadri, N Iqbal, L Stern, M Williams, KL Chicano, DA Daily, J McGrory, EJ Gracely, DJ Rader, FF Samaha	The American Journal of Medicine	2004
Chylomicron and VLDL TAG structures and postprandial lipid response induced by lard and modified lard KM Yli-Jokipii, US Schwab, RL Tahvonen, JP Kurvinen, HM Mykkänen, HP Kallio	Lipids	2003
Effect of meal sequence on postprandial lipid, glucose and insulin responses in young men GC Burdge, AE Jones, SM Frye, L Goodson, SA Wootton	European Journal of Clinical Nutrition	2003
Postprandial enrichment of remnant lipoproteins with apoC-I in healthy normolipidemic men with early asymptomatic atherosclerosis J Björkegren, A Silveira, S Boquist, R Tang, F Karpe, MG Bond, U Faire, A Hamsten	Arteriosclerosis, thrombosis, and vascular biology	2002
Insulin resistance affects the regulation of lipoprotein lipase in the postprandial period and in an adipose tissue-specific manner D Panarotto, P Remillard, L Bouffard, P Maheux	European Journal of Clinical Investigation	2002
Effects of atorvastatin on postprandial plasma lipoproteins in postinfarction patients with combined hyperlipidaemia S Boquist, F Karpe, K Danell-Toverud, A Hamsten	Atherosclerosis	2002
Apolipoprotein B Metabolism: Tracer Kinetics, Models, and Metabolic Studies JR Burnett, PH Barrett	Critical Reviews in Clinical Laboratory Sciences	2002
Cholesteryl ester flux from HDL to VLDL-1 is preferentially enhanced in type IIB hyperlipidemia in the postprandial state M Guerin, P Egger, C Soudant, WL Goff, A Tol, R Dupuis, MJ Chapman	Journal of lipid research	2002
Postprandial Lipemia is Associated With Platelet and Monocyte Activation and Increased Monocyte Cytokine Expression in Normolipemic Men DA Hyson, TG Paglieroni, T Wun, JC Rutledge	Clinical and Applied Thrombosis/Hemostasis	2002
Timing of vagal stimulation affects postprandial lipid metabolism in humans MD Robertson, AO Mason, KN Frayn	The American journal of clinical nutrition	2002
Postprandial changes of apoB-100 and apoB-48 in TG rich lipoproteins in familial combined hyperlipidemia C Verseyden, S Meijssen, MC Cabezas	Journal of lipid research	2002
Therapeutic considerations for postprandial dyslipidaemia JR Burnett, GF Watts	Diabetes, Obesity and Metabolism	2001
Isolation of remnant particles by immunoseparation: a new approach for investigation of postprandial lipoprotein metabolism in normolipidemic subjects P Schreuder	Atherosclerosis	2001
Measurement of human chylomicron triglyceride clearance with a labeled commercial lipid emulsion Y Park, BD Damron, JM Miles, WS Harris	Lipids	2001
Effects of androgen manipulation on postprandial triglyceridaemia, low-density lipoprotein particle size and lipoprotein(a) in men MS Hislop, AS Gibson, MI Lambert, TD Noakes, AD Marais	Atherosclerosis	2001
Effect of 6 dietary fatty acids on the postprandial lipid profile, plasma fatty acids, lipoprotein lipase, and cholesterol ester transfer activities in healthy young men T Tholstrup, B Sandström, A Bysted, G Hølmer	The American journal of clinical nutrition	2001
Fate of intravenously administered squalene and plant sterols in human subjects H Relas, H Gylling, TA Miettinen	Journal of lipid research	2001
Postprandial lipemia and coronary risk W Patsch, H Esterbauer, B Föger, JR Patsch	Current Atherosclerosis Reports	2000
Postprandial Retinyl Palmitate and Squalene Metabolism Is Age Dependent H Relas, H Gylling, RA Rajaratnam, TA Miettinen	The Journals of Gerontology Series A: Biological Sciences and Medical Sciences	2000
Is abnormal postprandial lipemia a familial risk factor for coronary artery disease in individuals with normal fasting concentrations of triglycerides and cholesterol? K Przybycien, Z Kornacewicz-Jach, B Torbus-Lisiecka, M Naruszewicz	Coronary Artery Disease	2000
The contribution of candidate genes to the response of plasma lipids and lipoproteins to dietary challenge Y Friedlander, E Leitersdorf, R Vecsler, H Funke, J Kark	Atherosclerosis	2000
Decreased Hepatic Expression of the Low-Density Lipoprotein (LDL) Receptor and LDL Receptor-Related Protein in Aging Rats Is Associated With Delayed Clearance of Chylomicrons From the Circulation PA Field, GF Gibbons	Metabolism	2000
Effect of stanol ester on postabsorptive squalene and retinyl palmitate H Relas, H Gylling, TA Miettinen	Metabolism	2000
Mobilisation of triacylglycerol stores GF Gibbons, K Islam, RJ Pease	Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids	2000
Intestinal absorption of β-carotene ingested with a meal rich in sunflower oil or beef tallow: postprandial appearance in triacylglycerol-rich lipoproteins in women X Hu, RJ Jandacek, WS White	The American journal of clinical nutrition	2000
Differences in glucose-dependent insulinotrophic polypeptide hormone and hepatic lipase in subjects of southern and northern Europe: implications for postprandial lipemia KG Jackson, A Zampelas, JM Knapper, HM Roche, MJ Gibney, A Kafatos, BJ Gould, JW Wright, CM Williams	The American journal of clinical nutrition	2000
Dietary medium-chain triacylglycerol prevents the postprandial rise of plasma triacylglycerols but induces hypercholesterolemia in primary hypertriglyceridemic subjects L Asakura, AM Lottenberg, MQ Neves, VS Nunes, JC Rocha, M Passarelli, ER Nakandakare, EC Quintão	The American journal of clinical nutrition	2000
Effect of postprandial lipaemia and Taq 1B polymorphism of the cholesteryl ester transfer protein (CETP) gene on CETP mass, activity, associated lipoproteins and plasma lipids E Noone, HM Roche, I Black, AM Tully, MJ Gibney	British Journal of Nutrition	2000
Remnant-like particle cholesterol and triglyceride levels of hypertriglyceridemic patients in the fed and fasted state C Marcoux, PN Hopkins, T Wang, ET Leary, K Nakajima, J Davignon, JS Cohn	Journal of lipid research	2000
Atorvastatin Improves Postprandial Lipoprotein Metabolism in Normolipidemic Subjects1 KG Parhofer, PH Barrett, P Schwandt	The Journal of clinical endocrinology and metabolism	2000
Insulin-like growth factor-I lowers fasting and postprandial triglyceride levels without affecting chylomicron clearance in healthy men T Bianda, J Zapf, ER Froesch, C Schmid	Journal of Internal Medicine	1999
Understanding coronary heart disease as a consequence of defective regulation of apolipoprotein B metabolism CJ Packard	Current Opinion in Lipidology	1999
Improvement of endothelial vasomotor dysfunction by treatment with alpha-tocopherol in patients with high remnant lipoproteins levels K Kugiyama, T Motoyama, H Doi, H Kawano, N Hirai, H Soejima, Y Miyao, K Takazoe, Y Moriyama, Y Mizuno, R Tsunoda, H Ogawa, T Sakamoto, S Sugiyama, H Yasue	Journal of the American College of Cardiology	1999
Differences in postprandial concentrations of very—low-density lipoprotein and chylomicron remnants between normotriglyceridemic and hypertriglyceridemic men with and without coronary heart disease F Karpe, ML Hellénius, A Hamsten	Metabolism	1999
Human apolipoprotein (Apo) B-48 and ApoB-100 kinetics with stable isotopes FK Welty, AH Lichtenstein, PH Barrett, GG Dolnikowski, EJ Schaefer	Arteriosclerosis, thrombosis, and vascular biology	1999
Postprandial lipoprotein metabolism and atherosclerosis F Karpe	Journal of Internal Medicine	1999
(n-3) Fatty Acid Supplementation in Moderately Hypertriglyceridemic Adults Changes Postprandial Lipid and Apolipoprotein B Responses to a Standardized Test Meal LF Tinker, EJ Parks, SR Behr, BO Schneeman, PA Davis	The Journal of nutrition	1999
Postprandial Triacylglycerols from Dietary Virgin Olive Oil Are Selectively Cleared in Humans R Abia, JS Perona, YM Pacheco, E Montero, FJ Muriana, V Ruiz-Gutiérrez	The Journal of nutrition	1999
Alimentary Lipemia, Postprandial Triglyceride-Rich Lipoproteins, and Common Carotid Intima-Media Thickness in Healthy, Middle-Aged Men S Boquist, G Ruotolo, R Tang, J Björkegren, MG Bond, U de Faire, F Karpe, A Hamsten	Circulation	1999
Detection, Quantification, and Characterization of Potentially Atherogenic Triglyceride-Rich Remnant Lipoproteins JS Cohn, C Marcoux, J Davignon	Arteriosclerosis, thrombosis, and vascular biology	1999
Effects of Native, Triglyceride-Enriched, and Oxidatively Modified LDL on Plasminogen Activator Inhibitor-1 Expression in Human Endothelial Cells BA Allison, L Nilsson, F Karpe, A Hamsten, P Eriksson	Arteriosclerosis, thrombosis, and vascular biology	1999
Differential binding of triglyceride-rich lipoproteins to lipoprotein lipase SQ Xiang, K Cianflone, D Kalant, AD Sniderman	Journal of lipid research	1999
VLDL activation of plasminogen activator inhibitor-1 (PAI-1) expression: involvement of the VLDL receptor L Nilsson, M Gåfvels, L Musakka, K Ensler, DK Strickland, B Angelin, A Hamsten, P Eriksson	Journal of lipid research	1999
Delayed increase in high density lipoprotein-phospholipids after ingestion of a fat load in normolipidemic patients with coronary artery disease JE Groener, LM Scheek, E Ramshorst, XH Krauss, A Tol	Atherosclerosis	1998
β-VLDL accumulation in familial dysbetalipoproteinemia is associated with increased exchange or diffusion of chylomicron lipids to apo B-100 containing triglyceride-rich lipoproteins PN Demacker, SJ Bredie, JM Vogelaar, MP Hectors, P Heijst, PM Stuyt, AF Stalenhoef	Atherosclerosis	1998
Comparison of three fatty meals in healthy normolipidaemic men: high post-prandial retinyl ester response to soybean oil Mero, Syvanne, Rosseneu, Labeur, Hilden, Taskinen	European Journal of Clinical Investigation	1998
Kinetics of triglyceride rich lipoproteins: chylomicrons and very low density lipoproteins PH Barrett	Atherosclerosis	1998
Effects of a cardioselective β-blocker on postprandial triglyceride-rich lipoproteins, low density lipoprotein particle size and glucose-insulin homeostasis in middle-aged men with modestly increased cardiovascular risk S Boquist, G Ruotolo, ML Hellénius, K Danell-Toverud, F Karpe, A Hamsten	Atherosclerosis	1998
Magnitude of alimentary lipemia is related to intima-media thickness of the common carotid artery in middle-aged men F Karpe, U Faire, M Mercuri, MG Bond, ML Hellénius, A Hamsten	Atherosclerosis	1998
Effect of acarbose on postprandial lipid metabolism in type 2 diabetes mellitus S Kado	Diabetes Research and Clinical Practice	1998
Alimentary lipemia enhances the membrane expression of platelet P-selectin without affecting other markers of platelet activation A Bröijersén, F Karpe, A Hamsten, AH Goodall, P Hjemdahl	Atherosclerosis	1998
Very-low-density lipoprotein response element in the promoter region of the human plasminogen activator inhibitor-1 gene implicated in the impaired fibrinolysis of hypertriglyceridemia P Eriksson, L Nilsson, F Karpe, A Hamsten	Arteriosclerosis, thrombosis, and vascular biology	1998
Single daily oral dose of gemfibrozil reduces postprandial hyperlipidemia in hyperlipidemic patients O Descamps, JC Hondekijn, T Godrie, JP Desager, FR Heller	Current Therapeutic Research	1998
Remnants of chylomicron and very low density lipoprotein impair endothelium-dependent vasorelaxation H Doi, K Kugiyama, M Ohgushi, S Sugiyama, T Matsumura, Y Ohta, T Nakano, K Nakajima, H Yasue	Atherosclerosis	1998
Unsaturated Fatty Acids Increase Plasminogen Activator Inhibitor-1 Expression in Endothelial Cells L Nilsson, C Banfi, U Diczfalusy, E Tremoli, A Hamsten, P Eriksson	Arteriosclerosis, thrombosis, and vascular biology	1998
The HMG-CoA Reductase Inhibitor Atorvastatin Increases the Fractional Clearance Rate of Postprandial Triglyceride-Rich Lipoproteins in Miniature Pigs JR Burnett, PH Barrett, P Vicini, DB Miller, DE Telford, SJ Kleinstiver, MW Huff	Arteriosclerosis, thrombosis, and vascular biology	1998
Transient triglyceridemia in healthy normolipidemic men increases cellular processing of large very low density lipoproteins by fibroblasts in vitro J Björkegren, F Karpe, S Vitols, P Tornvall, A Hamsten	Journal of lipid research	1998
Differences in apolipoprotein and lipid composition between human chylomicron remnants and very low density lipoproteins isolated from fasting and postprandial plasma J Björkegren, F Karpe, RW Milne, A Hamsten	Journal of lipid research	1998
Preferential clearance of apoB-48-containing lipoproteins after heparin-induced lipolysis is modulated by lipoprotein lipase activity AP van Beek, HH van Barlingen, FC de Ruijter-Heijstek, H Jansen, DW Erkelens, GM Dallinga-Thie, TW de Bruin	Journal of lipid research	1998
Apolipoprotein B-48 and retinyl palmitate are not equivalent markers of postprandial intestinal lipoproteins S Lemieux, R Fontani, KD Uffelman, GF Lewis, G Steiner	Journal of lipid research	1998
Postprandial lipid metabolism in relation to coronary heart disease F Karpe	Proceedings of the Nutrition Society	1997
Low-density lipoprotein subclasses: mechanisms of formation and modulation BA Griffin	Proceedings of the Nutrition Society	1997
Postprandial hemorrheology and apolipoprotein B metabolism in patients with familial hypertriglyceridemia C Otto, V Pschierer, AC Soennichsen, P Schwandt, WO Richter	Metabolism	1997
Very-low-density lipoprotein subfraction composition and metabolism by adipose tissue RM Fisher, JM Miles, BA Kottke, KN Frayn, SW Coppack	Metabolism	1997
Olive oil increases the magnitude of postprandial chylomicron remnants compared to milk fat and safflower oil K Higashi, T Ishikawa, H Shige, K Tomiyasu, H Yoshida, T Ito, K Nakajima, A Yonemura, S Sawada, H Nakamura	Journal of the American College of Nutrition	1997
Influence of apo E phenotype on postprandial triglyceride and glucose responses in subjects with and without coronary heart disease A Dart	Atherosclerosis	1997
Lipoprotein Heterogeneity and Apolipoprotein B Metabolism CJ Packard, J Shepherd	Arteriosclerosis, thrombosis, and vascular biology	1997
Clearance of lipoprotein remnant particles in adipose tissue and muscle in humans F Karpe, SM Humphreys, JS Samra, LK Summers, KN Frayn	Journal of lipid research	1997
Alterations of VLDL composition during alimentary lipemia J Björkegren, A Hamsten, RW Milne, F Karpe	Journal of lipid research	1997
Guinea pig apolipoprotein C-II: expression in E. coli, functional studies of recombinant wild-type and mutated variants, and distribution on plasma lipoproteins Y Andersson, A Lookene, Y Shen, S Nilsson, L Thelander, G Olivecrona	Journal of lipid research	1997
Lipoprotein lipase deficiency with pancreatitis in mink: biochemical characterization and pathology B Christophersen, K Nordstoga, Y Shen, T Olivecrona, G Olivecrona	Journal of lipid research	1997
Abnormal postprandial apolipoprotein B-48 and triglyceride responses in normolipidemic women with greater than 70% stenotic coronary artery disease: a case-control study E Meyer, HT Westerveld, FC de Ruyter-Meijstek, MM van Greevenbroek, R Rienks, HJ van Rijn, DW Erkelens, TW de Bruin	Atherosclerosis	1996
Disposition of lipids in the postprandial state CM Williams	Proceedings of the Nutrition Society	1996
Hypertriglyceridemia and its Metabolic Consequences as a Risk Factor for Atherosclerotic Cardiovascular Disease in Non-Insulin-Dependent Diabetes Mellitus GF Lewis, G Steiner	Diabetes/Metabolism Reviews	1996
Elevated triglyceride-rich lipoproteins in diabetes A Curtin, P Deegan, D Owens, P Collins, A Johnson, GH Tomkin	Acta Diabetologica	1996
Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis IJ Goldberg	Journal of lipid research	1996
Method to measure apolipoprotein B-48 and B-100 secretion rates in an individual mouse: evidence for a very rapid turnover of VLDL and preferential removal of B-48- relative to B-100-containing lipoproteins X Li, F Catalina, SM Grundy, S Patel	Journal of lipid research	1996
A frequently occurring mutation in the lipoprotein lipase gene (Asn291Ser) results in altered postprandial chylomicron triglyceride and retinyl palmitate response in normolipidemic carriers SN Pimstone, SM Clee, SE Gagné, L Miao, H Zhang, EA Stein, MR Hayden	Journal of lipid research	1996
Accumulation of large very low density lipoprotein in plasma during intravenous infusion of a chylomicron-like triglyceride emulsion reflects competition for a common lipolytic pathway J Bjorkegren, CJ Packard, A Hamsten, D Bedford, M Caslake, L Foster, J Shepherd, P Stewart, F Karpe	Journal of lipid research	1996
Elevated triglyceride-rich lipoproteins in diabetes: A study of apolipoprotein B-48 A Curtin, P Deegan, D Owens, P Collins, A Johnson, GH Tomkin	Acta Diabetologica	1996
Common variation in the gene for apolipoprotein B modulates postprandial lipoprotein metabolism: a hypothesis generating study RE Peacock, F Karpe, PJ Talmud, A Hamsten, SE Humphries	Atherosclerosis	1995
Postprandial triacylglycerolaemia—Nutritional implications HM Roche, MJ Gibney	Progress in Lipid Research	1995
Modulation of low density lipoprotein subclasses by alimentary lipemia in control and normotriglyceridemic non-insulin-dependent diabetic subjects N Attia, V Durlach, JL Paul, T Soni, D Betoulle, A Girard-Globa	Atherosclerosis	1995
Lipid intolerance in smokers M Axelsen, B Eliasson, E Joheim, RA Lenner, MR Taskinen, U Smith	Journal of Internal Medicine	1995
Relationships between triglycerides, lipoproteins, glucose and coronary artery disease GA Hobbs, SG Wagner, SS Levinson	Clinica Chimica Acta	1995
Dietary rat models in which the development of hypertriglyceridemia and that of insulin resistance are dissociated A Boivin, Y Deshaies	Metabolism	1995
Low-density lipoprotein heterogeneity BA Griffin	Baillière's Clinical Endocrinology and Metabolism	1995
Association of postprandial triglyceride and retinyl palmitate responses with newly diagnosed exercise-induced myocardial ischemia in middle-aged men and women HN Ginsberg, J Jones, WS Blaner, A Thomas, W Karmally, L Fields, D Blood, MD Begg	Arteriosclerosis, thrombosis, and vascular biology	1995
Post-prandial lipaemia R Kirchmair, CF Ebenbichler, JR Patsch	Baillière's Clinical Endocrinology and Metabolism	1995
Influence of Diets Rich in Saturated and Omega-6 Polyunsaturated Fatty Acids on the Postprandial Responses of Apolipoproteins B-48, B-100, E, and Lipids in Triglyceride-Rich Lipoproteins N Bergeron, RJ Havel	Arteriosclerosis, thrombosis, and vascular biology	1995
Lipoprotein Lipase Mass and Activity in Plasma and Their Increase After Heparin Are Separate Parameters With Different Relations to Plasma Lipoproteins P Tornvall, G Olivecrona, F Karpe, A Hamsten, T Olivecrona	Arteriosclerosis, thrombosis, and vascular biology	1995
Quantification of Postprandial Triglyceride-Rich Lipoproteins in Healthy Men by Retinyl Ester Labeling and Simultaneous Measurement of Apolipoproteins B-48 and B-100 F Karpe, M Bell, J Björkegren, A Hamsten	Arteriosclerosis, thrombosis, and vascular biology	1995
Quantification of apolipoproteins B-100, B-48, and E in human triglyceride-rich lipoproteins L Kotite, N Bergeron, RJ Havel	Journal of lipid research	1995
Endogenous triglyceride-rich lipoproteins accumulate in rat plasma when competing with a chylomicron-like triglyceride emulsion for a common lipolytic pathway F Karpe, M Hultin	Journal of lipid research	1995
Fasting plasma triacylglycerol concentrations predict adverse changes in lipoprotein metabolism after a normal meal JL Potts, SM Humphreys, SW Coppack, RM Fisher, GF Gibbons, KN Fray	British Journal of Nutrition	1994
Postprandial lipoproteins and progression of coronary atherosclerosis F Karpe, G Steiner, K Uffelman, T Olivecrona, A Hamsten	Atherosclerosis	1994
Postprandial apolipoprotein B100 and B48 metabolism in familial combined hyperlipidaemia before and after reduction of fasting plasma triglycerides* MC Cabezas, DW Erkelens, LA Kock, TW de Bruin	European Journal of Clinical Investigation	1994
Evaluation of effects of unmodified niacin on fasting and postprandial plasma lipids in normolipidemic men with hypoalphalipoproteinemia JM King, JR Crouse, JG Terry, TM Morgan, BJ Spray, NE Miller	The American Journal of Medicine	1994
Activation of coagulation factor VII during alimentary lipemia A Silveira, F Karpe, M Blombäck, G Steiner, G Walldius, A Hamsten	Arteriosclerosis Thrombosis and Vascular Biology	1994
Abnormal metabolism of postprandial lipoproteins in patients with non-insulin-dependent diabetes mellitus is not related to coronary artery disease M Syvänne, H Hilden, MR Taskinen	Journal of lipid research	1994
Determination of apolipoproteins B-48 and B-100 in triglyceride-rich lipoproteins by analytical SDS-PAGE F Karpe, A Hamsten	Journal of lipid research	1994
Clinical Relevance of Reducing Triglycerides: Implications for Ischaemic Heart Disease Treatment AN Nafziger	Drugs	1994
Human intestinal alkaline phosphatase—release to the blood is linked to lipid absorption, but removal from the blood is not linked to lipoprotein clearance U Domar, F Karpe, A Hamsten, T Stigbrand, T Olivecrona	European Journal of Clinical Investigation	1993
Low density lipoprotein receptors bind and mediate cellular catabolism of normal very low density lipoproteins in vitro DA Chappell, GL Fry, MA Waknitz, LE Muhonen, MW Pladet	The Journal of biological chemistry	1993

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