JCI - Citations to Purification and partial sequencing of the nuclear autoantigen RA33 shows that it is indistinguishable from the A2 protein of the heterogeneous nuclear ribonucleoprotein complex.

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Purification and partial sequencing of the nuclear autoantigen RA33 shows that it is indistinguishable from the A2 protein of the heterogeneous nuclear ribonucleoprotein complex.

G Steiner, … , A Barta, J S Smolen

G Steiner, … , A Barta, J S Smolen

Published September 1, 1992
Citation Information: J Clin Invest. 1992;90(3):1061-1066. https://doi.org/10.1172/JCI115921.

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Biomarkers for rheumatoid arthritis: From molecular processes to diagnostic applications-current concepts and future perspectives B Nakken, G Papp, V Bosnes, M Zeher, G Nagy, P Szodoray	Immunology Letters	2017
cDNA phage display for the discovery of theranostic autoantibodies in rheumatoid arthritis P Vandormael, P Verschueren, LD Winter, V Somers	Immunologic Research	2016
Antibodies to native and citrullinated RA33 (hnRNP A2/B1) challenge citrullination as the inciting principle underlying loss of tolerance in rheumatoid arthritis MF Konig, JT Giles, PA Nigrovic, F Andrade	Annals of the rheumatic diseases	2016
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Autoantibody to heterogeneous nuclear ribonucleoprotein-A2 (RA33) in juvenile idiopathic arthritis: Clinical significance HY Tomoum, GA Mostafa, EM El-Shahat	Pediatrics International	2009
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What can we learn from the presence of anti-cyclic citrullinated peptide antibodies in systemic lupus erythematosus? Y Zhao, J Li, X Li, C Li, L Li, Z Li	Joint Bone Spine	2009
Kelley's Textbook of Rheumatology J Degroot, AM Zuurmond, PP Tak	Kelley's Textbook of Rheumatology	2009
Anticorps anti-peptides cycliques citrullinés dans le lupus érythémateux systémique Y Zhao, J Li, X Li, C Li, L Li, Z Li	Revue du Rhumatisme	2009
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Proteomic analysis of autoantigens associated with systemic lupus erythematosus: Anti-aldolase A antibody as a potential marker of lupus nephritis S Serada, M Fujimoto, T Takahashi, P He, A Hayashi, T Tanaka, K Hagihara, T Yamadori, M Mochizuki, N Norioka, S Norioka, I Kawase, T Naka	PROTEOMICS – CLINICAL APPLICATIONS	2007
The Rheumatoid Arthritis-Associated Autoantigen hnRNP-A2 (RA33) Is a Major Stimulator of Autoimmunity in Rats with Pristane-Induced Arthritis MH Hoffmann, J Tuncel, K Skriner, M Tohidast-Akrad, B Türk, S Pinol-Roma, G Serre, G Schett, JS Smolen, R Holmdahl, G Steiner	Journal of immunology (Baltimore, Md. : 1950)	2007
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Update on autoantibodies in rheumatoid arthritis SL Bridges	Current Rheumatology Reports	2004
Autoantibodies against heterogeneous nuclear ribonucleoprotein B1 in CSF of MS patients E Sueoka, M Yukitake, K Iwanaga, N Sueoka, T Aihara, Y Kuroda	Annals of Neurology	2004
Anti-CCP antibodies, a highly specific marker for (early) rheumatoid arthritis ER Vossenaar, WJ van Venrooij	Clinical and Applied Immunology Reviews	2004
Advances in B-cell epitope analysis of autoantigens in connective tissue diseases M Mahler, M Blüthner, KM Pollard	Clinical Immunology	2003
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Characterization of autoreactive T cells to the autoantigens heterogeneous nuclear ribonucleoprotein A2 (RA33) and filaggrin in patients with rheumatoid arthritis R Fritsch, D Eselböck, K Skriner, B Jahn-Schmid, C Scheinecker, B Bohle, M Tohidast-Akrad, S Hayer, J Neumüller, S Pinol-Roma, JS Smolen, G Steiner	Journal of immunology (Baltimore, Md. : 1950)	2002
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Autoantibody systems in rheumatoid arthritis: specificity, sensitivity and diagnostic value MA van Boekel, ER Vossenaar, FH van Hoogen, WJ van Venrooij	Arthritis research	2001
Rheumatoid factors, anti-filaggrin antibodies and low in vitro interleukin-2 and interferon-γ production are useful immunological markers for early diagnosis of community cases of rheumatoid arthritis. A preliminary study O Vittecoq, F Jouen-Beades, K Krzanowska, I Bichon-Tauvel, JF Ménard, A Daragon, F Tron, XL Loët	Joint Bone Spine	2001
Les facteurs rhumatoïdes, les anticorps antifilaggrine et la faible production in vitro d’interleukine 2 et d’interféron-γ sont des marqueurs immunologiques utiles au diagnostic précoce de la polyarthrite rhumatoïde dans une population de recrutement libéral. Étude préliminaire O Vittecoq, F Jouen-Beades, K Krzanowska, I Bichon-Tauvel, JF Ménard, A Daragon, F Tron, XL Loët	Revue du Rhumatisme	2001
Progress in the use of biochemical and biological markers for evaluation of rheumatoid arthritis Nakamura RM	Journal of Clinical Laboratory Analysis	2001
Progress in the use of biochemical and biological markers for evaluation of rheumatoid arthritis RM Nakamura	Journal of Clinical Laboratory Analysis	2000
In the rheumatoid pannus, anti-filaggrin autoantibodies are produced by local plasma cells and constitute a higher proportion of IgG than in synovial fluid and serum C Masson-Bessière, M Sebbag, JJ Durieux, L Nogueira, C Vincent, E Girbal-Neuhauser, R Durroux, A Cantagrel, G Serre	Clinical & Experimental Immunology	2000
Mouse homologue of the human SART3 gene encoding tumor-rejection antigen K Harada, A Yamada, T Mine, N Kawagoe, H Takasu, K Itoh	Japanese journal of cancer research : Gann	2000
Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset R Goldbach-Mansky, J Lee, A McCoy, J Hoxworth, C Yarboro, JS Smolen, G Steiner, A Rosen, C Zhang, HA Ménard, ZJ Zhou, T Palosuo, WJ Venrooij, RL Wilder, JH Klippel, HR Schumacher, HS El-Gabalawy	Arthritis Research & Therapy	2000
B and T Cell Responses to the Spliceosomal Heterogeneous Nuclear Ribonucleoproteins A2 and B1 in Normal and Lupus Mice H Dumortier, F Monneaux, B Jahn-Schmid, JP Briand, K Skriner, PL Cohen, JS Smolen, G Steiner, S Muller	Journal of immunology (Baltimore, Md. : 1950)	2000
Mouse homologue of the human SART3 gene encoding tumor-rejection antigen. Harada K, Yamada A, Mine T, Kawagoe N, Takasu H, Itoh K	Japanese journal of cancer research : Gann	2000
Serum samples of patients with rheumatoid arthritis contain a specific autoantibody to "denatured" aldolase A in the osteoblast-like cell line, MG-63 F Ukaji, I Kitajima, T Kubo, C Shimizu, T Nakajima, I Maruyama	Annals of the rheumatic diseases	1999
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Molecular definition of heterogeneous nuclear ribonucleoprotein R (hnRNP R) using autoimmune antibody: Immunological relationship with hnRNP P W Hassfeld, EK Chan, DA Mathison, D Portman, G Dreyfuss, G Steiner, EM Tan	Nucleic Acids Research	1998
Autoantibodies to a Novel Early Endosome Antigen 1 RL Waite, JW Sentry, H Stenmark, BH Toh	Clinical Immunology and Immunopathology	1998
The concurrence of rheumatoid arthritis and limited systemic sclerosis: Clinical and serologic characteristics of an overlap syndrome C Zimmermann, G Steiner, K Skriner, W Hassfeld, P Petera, JS Smolen	Arthritis & Rheumatism	1998
Anti-A2/RA33 autoantibodies are directed to the RNA binding region of the A2 protein of the heterogeneous nuclear ribonucleoprotein complex. Differential epitope recognition in rheumatoid arthritis, systemic lupus erythematosus, and mixed connective tissu K Skriner, WH Sommergruber, V Tremmel, I Fischer, A Barta, JS Smolen, G Steiner	Journal of Clinical Investigation	1997
Reference sera for antinuclear antibodies. II. Further definition of antibody specificities in international antinuclear antibody reference sera by immunofluorescence and western blotting JS Smolen, B Butcher, MJ Fritzler, T Gordon, J Hardin, JR Kalden, R Lahita, RN Maini, W Reeves, M Reichlin, N Rothfield, Y Takasaki, WJ van Venrooij, EM Tan	Arthritis & Rheumatism	1997
Heterogenous nuclear RNP C1 and C2 core proteins are targets for an autoantibody found in the serum of a patient with systemic sclerosis and psoriatic arthritis J Vencovský, J Kafková, D Staněk, I Raška	Arthritis & Rheumatism	1997
The p542 Gene Encodes an Autoantigen that Cross-Reacts with EBNA-1 of the Epstein Barr Virus and which may be a Heterogeneous Nuclear Ribonucleoprotein GH Rhodes, JR Valbracht, MD Nguyen, JH Vaughan	Journal of Autoimmunity	1997
Normal human epidermal keratinocytes express in vitro specific molecular forms of (pro)filaggrin recognized by rheumatoid arthritis-associated antifilaggrin autoantibodies E Girbal-Neuhauser, M Montézin, F Croute, M Sebbag, M Simon, JJ Durieux, G Serre	Molecular Medicine	1997
Recognition of subsets of the mammalian A/B-type core heterogeneous nuclear ribonucleoprotein polypeptides by novel autoantibodies A Dangli, A Plomaritoglou, E Boutou, N Vassiliadou, HM Moutsopoulos, A Guialis	Biochemical Journal	1996
Manual of Biological Markers of Disease WJ van Venrooij, RN Maini		1996
Autoimmune diseases: nuclear autoantigens can be found at the cell-surface P Jordan, D Kbler	Molecular Biology Reports	1996
Clinical and immunological aspects of autoantibodies to RA33/hnRNP-A/B proteins ? A link between RA, SLE and MCTD G Steiner, K Skriner, W Hassfeld, JS Smolen	Molecular Biology Reports	1996
Detection and expression of a cDNA clone that encodes a polypeptide containing two inhibitory domains of human calpastatin and its recognition by rheumatoid arthritis sera N Després, G Talbot, B Plouffe, G Boire, HA Ménard	Journal of Clinical Investigation	1995
The antiperinuclear factor and the so-called antikeratin antibodies are the same rheumatoid arthritis-specific autoantibodies M Sebbag, M Simon, C Vincent, C Masson-Bessière, E Girbal, JJ Durieux, G Serre	Journal of Clinical Investigation	1995
Autoimmune response to the spliceosome W Hassfeld, GÜ Steiner, A Studnicka-Benke, K Skriner, W Graninger, I Fischer, JS Smolen	Arthritis & Rheumatism	1995
Antibodies to synovial antigens in recent-onset rheumatoid arthritis GJ Mccol, DS Cram, LC Harrison	Arthritis & Rheumatism	1995
Marker antibodies of rheumatoid arthritis: Diagnostic and pathogenetic implications K Aho, T Palosuo, P Kurki	Seminars in Arthritis and Rheumatism	1994
Immunology of the Connective Tissue Diseases GS Panayi		1994
Immunoblotting detection of so-called 'antikeratin antibodies': a new assay for the diagnosis of rheumatoid arthritis V Gomes-Daudrix, M Sebbag, E Girbal, C Vincent, M Simon, J Rakotoarivony, M Abbal, B Fournie, G Serre	Annals of the rheumatic diseases	1994
Conserved Structures and Diversity of Functions of RNA-Binding Proteins CG Burd, G Dreyfuss	Science	1994
The cytokeratin filament-aggregating protein filaggrin is the target of the so-called "antikeratin antibodies," autoantibodies specific for rheumatoid arthritis M Simon, E Girbal, M Sebbag, V Gomès-Daudrix, C Vincent, G Salama, G Serre	Journal of Clinical Investigation	1993
The Kaleidoscope of Autoimmunity Y Shoenfeld	Autoimmunity	1993
Autoantibodies MH Lessof, SP Asper	American Heart Journal	1960

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