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Inactivation of endothelial derived relaxing factor by oxidized lipoproteins.

J H Chin, … , S Azhar, B B Hoffman

J H Chin, … , S Azhar, B B Hoffman

Published January 1, 1992
Citation Information: J Clin Invest. 1992;89(1):10-18. https://doi.org/10.1172/JCI115549.

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Effects of atorvastatin treatment on the oxidatively modified low density lipoprotein in hyperlipidemic patients Q Zhu, J McMaster, D Mymin, T Dembinski, G Hatch, P C Choy, E A Kroeger	Molecular and Cellular Biochemistry	2000
Homocysteine, a risk factor for cardiovascular disease K Prasad	International Journal of Angiology	1999
A Single High Dose of Vitamin C Counteracts the Acute Negative Effect on Microcirculation Induced by Smoking a Cigarette J Zhang, X Ying, Q Lu, A Kallner, RJ Xiu, P Henriksson, I Björkhem	Microvascular Research	1999
Role of oxidatively modified low density lipoproteins and anti-oxidants in atherothrombosis P Holvoet	Expert Opinion on Investigational Drugs	1999
Oxidative stress and diabetes mellitus Pathogenesis of long-term complications J Kuyvenhoven	European Journal of Internal Medicine	1999
HMG CoA reductase inhibitors are related to improved systemic endothelial function in coronary artery disease MJ Järvisalo, JO Toikka, T Vasankari, J Mikkola, JS Viikari, JJ Hartiala, OT Raitakari	Atherosclerosis	1999
Constantly low HDL-cholesterol concentration relates to endothelial dysfunction and increased in vivo LDL-oxidation in healthy young men JO Toikka, M Ahotupa, JS Viikari, H Niinikoski, MR Taskinen, K Irjala, JJ Hartiala, OT Raitakari	Atherosclerosis	1999
Vitamin E improves arterial compliance in middle-aged men and women P Mottram	Atherosclerosis	1999
Endothelium-dependent relaxation by acetylcholine is impaired in hypertriglyceridemic humans with normal levels of plasma LDL cholesterol TV Lewis, AM Dart, JP Chin-Dusting	Journal of the American College of Cardiology	1999
Endothelial Dysfunction, Oxidation of Low-Density Lipoprotein, and Cardiovascular Disease P Holvoet	Therapeutic Apheresis and Dialysis	1999
Oxidized LDL from subjects with different dietary habits modifies atherogenic processes in endothelial and smooth muscle cells TA Lähteenmäki, L Seppo, J Laakso, R Korpela, H Vanhanen, MJ Tikkanen, H Vapaatalo	Life Sciences	1999
Oxidant stress in the vasculature M Maytin, J Leopold, J Loscalzo	Current Atherosclerosis Reports	1999
Cholesterol lowering and endothelial function RA Vogel	The American Journal of Medicine	1999
Lipid peroxidation and atherosclerosis in type II diabetes WA Oranje, BH Wolffenbuttel	Journal of Laboratory and Clinical Medicine	1999
Mechanism by which quinapril improves vascular function in coronary artery disease KK Koh, MN Bui, L Hathaway, G Csako, MA Waclawiw, JA Panza, RO Cannon	The American Journal of Cardiology	1999
Effects of age, gender and metabolic factors on endothelium-dependent vasodilation: a population-based study M Sarabi, J Millgård, L Lind	Journal of Internal Medicine	1999
Inhibition by a coantioxidant of aortic lipoprotein lipid peroxidation and atherosclerosis in apolipoprotein E and low density lipoprotein receptor gene double knockout mice PK Witting, K Pettersson, AM Ostlund-Lindqvist, C Westerlund, AW Eriksson, R Stocker	The FASEB Journal	1999
ANTIOXIDANT VITAMINS AND PREVENTION OF CARDIOVASCULAR DISEASE: LABORATORY, EPIDEMIOLOGICAL AND CLINICAL TRIAL DATA R MARCHIOLI	Pharmacological Research	1999
Possible role of high susceptibility of high-density lipoprotein to lipid peroxidative modification and oxidized high-density lipoprotein in genesis of coronary artery spasm H Ohmura, Y Watanabe, C Hatsumi, H Sato, H Daida, H Mokuno, H Yamaguchi	Atherosclerosis	1999
Pressor hyperreactivity to mental and hand-grip stresses in patients with hypercholesterolemia M Minami, K Atarashi, A Ishiyama, Y Hirata, A Goto, M Omata	Journal of Hypertension	1999
Relative Effects of α- and γ-Tocopherol on Low-Density Lipoprotein Oxidation and Superoxide Dismutase and Nitric Oxide Synthase Activity and Protein Expression in Rats D Li, T Saldeen, F Romeo, JL Mehta	Journal of cardiovascular pharmacology and therapeutics	1999
AT 1 Receptor Antagonism Reduces Endothelial Dysfunction and Intimal Thickening in Atherosclerotic Rabbits N de las Heras, P Aragoncillo, R Maeso, S Vazquez-Pérez, J Navarro-Cid, M DeGasparo, J Mann, LM Ruilope, V Cachofeiro, V Lahera	Hypertension	1999
Cytokines in Severe Sepsis and Septic Shock H Redl, G Schlag		1999
Molecular Cardiology in Clinical Practice M Sanders, JB Kostis		1999
Argatroban increases nitric oxide levels in patients with peripheral arterial obstructive disease: placebo-controlled study Y Ueki, K Matsumoto, Y Kizaki, K Yoshida, Y Matsunaga, M Yano, S Miyake, Y Tominaga, K Eguchi	Journal of Thrombosis and Thrombolysis	1999
A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans. Turpeinen AM, Basu S, Mutanen M	Lipids	1999
L-2-Oxothiazolidine-4-carboxylic acid reverses endothelial dysfunction in patients with coronary artery disease JA Vita, B Frei, M Holbrook, N Gokce, C Leaf, JF Keaney	Journal of Clinical Investigation	1998
Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells O Hernández-Perera, D Pérez-Sala, J Navarro-Antolín, R Sánchez-Pascuala, G Hernández, C Díaz, S Lamas	Journal of Clinical Investigation	1998
Dyslipoproteinaemia and hyperoxidative stress in the pathogenesis of endothelial dysfunction in non-insulin dependent diabetes mellitus: an hypothesis GF Watts, DA Playford	Atherosclerosis	1998
N-Acetylcysteine Enhances Endothelium-Dependent Vasorelaxation in the Isolated Rat Mesenteric Artery BL Lopez, JW Snyder, DS Birenbaum, X Ma	Annals of Emergency Medicine	1998
Cholesterol, endothelial function and cardiovascular disease IB Wilkinson, JR Cockcroft	Current Opinion in Lipidology	1998
Responses to endothelium-dependent agonists in subcutaneous arteries excised from hypercholesterolaemic men TV Lewis, BA Cooper, AM Dart, JP Chin-Dusting	British Journal of Pharmacology	1998
Efficient inhibition of intimal hyperplasia by adenovirus-mediated inducible nitric oxide synthase gene transfer to rats and pigs in vivo LL Shears, MR Kibbe, AD Murdock, TR Billiar, A Lizonova, I Kovesdi, SC Watkins, E Tzeng	Journal of the American College of Surgeons	1998
Endothelial dysfunction occurs in children with two genetic hyperlipidemias: Improvement with antioxidant vitamin therapy M Mietus-Snyder, MJ Malloy	The Journal of Pediatrics	1998
Glyc-oxidized LDL impair endothelial function more potently than oxidized LDL: role of enhanced oxidative stress J Galle, R Schneider, B Winner, C Lehmann-Bodem, R Schinzel, G Münch, E Conzelmann, C Wanner	Atherosclerosis	1998
Anti-oxidant status and lipid peroxidation in patients with essential hypertension C Russo, O Olivieri, D Girelli, G Faccini, ML Zenari, S Lombardi, R Corrocher	Journal of Hypertension	1998
The atherogenic lipoprotein phenotype and vascular endothelial dysfunction N Sattar, JR Petrie, AJ Jaap	Atherosclerosis	1998
Oxidized cholesterol in oxidized low density lipoprotein may be responsible for the inhibition of LPS-induced nitric oxide production in macrophages1The project was supported by National Natural Science Foundation of China.1 SX Liu, Y Chen, M Zhou, J Wan	Atherosclerosis	1998
Additional benefit of vitamin E supplementation to simvastatin therapy on vasoreactivity of the brachial artery of hypercholesterolemic men T Neunteufl, K Kostner, R Katzenschlager, M Zehetgruber, G Maurer, F Weidinger	Journal of the American College of Cardiology	1998
RESTORATION OF NITRIC OXIDE FUNCTION IN HUMAN HYPERLIPIDAEMIA, CONGESTIVE HEART FAILURE AND LIVER CIRRHOSIS JP Chin-Dusting, DM Kaye	Clinical and Experimental Pharmacology and Physiology	1998
A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans AM Turpeinen, S Basu, M Mutanen	Prostaglandins, Leukotrienes and Essential Fatty Acids	1998
Homocysteine and Atherothrombosis FH Epstein, GN Welch, J Loscalzo	New England Journal of Medicine	1998
A Protein-bound Polysaccharide Synergistic with Lipopolysaccharide Induces Nitric Oxide Release and Antioxidant Enzyme Activities in Mouse Peritoneal Macrophages ZJ Pang, M Zhou, Y Chen, J Wan	The American journal of Chinese medicine	1998
Oxidizability of low-density lipoproteins from neoral and tacrolimus-treated renal transplant patients Z Varghese, RL Fernando, G Turakhia, E Psimenou, C Brunton, ON Fernando, A Davenport, A Burns, P Sweny, SH Powis, JF Moorhead	Transplantation Proceedings	1998
Lipid Oxidation Products and Vascular Function KR Bruckdorfer	Free Radical Research	1998
Depression of endothelial and smooth muscle cell oxygen consumption by endotoxin R Motterlini, H Kerger, CJ Green, RM Winslow, M Intaglietta	American journal of physiology. Heart and circulatory physiology	1998
Oxidized LDL promotes vascular endothelial cell pinocytosis via a prooxidation mechanism S Chow, R Lee, SH Shih, J Chen	The FASEB Journal	1998
Oxidized Low Density Lipoproteins in Patients With Transplant-Associated Coronary Artery Disease P Holvoet, JM Stassen, JV Cleemput, D Collen, J Vanhaecke	Arteriosclerosis, thrombosis, and vascular biology	1998
Coronary Artery Responses to Physiological Stimuli Are Improved by Deferoxamine but not by l -Arginine in Non–Insulin-Dependent Diabetic Patients With Angiographically Normal Coronary Arteries and No Other Risk Factors A Nitenberg, F Paycha, S Ledoux, R Sachs, JR Attali, P Valensi	Circulation	1998
Inhibition by Cholesterol Oxides of NO Release From Human Vascular Endothelial Cells V Deckert, A Brunet, F Lantoine, G Lizard, EM Brussel, S Monier, L Lagrost, M David-Dufilho, P Gambert, MA Devynck	Arteriosclerosis, thrombosis, and vascular biology	1998
NITRIC OXIDE SYNTHASE: Role in the Genesis of Vascular Disease JP MD, VJ MD	Annual Review of Medicine	1997
The role of nitric oxide in cardiac surgery Y Nonami	Surgery Today	1997
Inhibition of Low-Density Lipoprotein Oxidation by Oral Herbal Mixtures Maharishi Amrit Kalash-4 and Maharishi Amrit Kalash-5 in Hyperlipidemic Patients V Sundaram, AN Hanna, GP Lubow, L Koneru, JM Falko, HM Sharma	The American Journal of the Medical Sciences	1997
Insulin and lipid metabolism: new developments in drug therapy AJ Mackay, JR Petrie	Expert Opinion on Investigational Drugs	1997
Increased nitric oxide deactivation by polymorphonuclear leukocytes in patients with intermittent claudication SE Akopov, SS Pogossian, EN Toromanian, GG Grigorian, ES Gabrielian	Journal of Vascular Surgery	1997
Progress in Interventional Cardiology JD Talley, P Manavalan, T Stewart	Journal of Interventional Cardiology	1997
The influence of oxidized lipoproteins, oxidation products and antioxidants on the release of nitric oxide from the endothelium and the response of platelets to nitric oxide KR Bruckdorfer, KM Naseem, B Mohammadi, S Chirico, C Ettelaie, A Gleeson, T Young, JM Adam, B Wilbourn, VO Skinner, AH Goodall, J Khan, SC Gates, M Jacobs	BioFactors	1997
Nitric oxide function in atherosclerosis KE Matthys, H Bult	Mediators of Inflammation	1997
Involvement of protein kinase C in the supersensitivity to 5-HT caused by oxidized low-density lipoproteins A Encabo, M Ferrer, MV Conde, A Porres, JA Gómez-Gerique, J Marín, G Balfagón	Life Sciences	1997
Modulatory role of lipoprotein oxidation on platelet-vessel wall interactions KR Bruckdorfer	Prostaglandins, Leukotrienes and Essential Fatty Acids	1997
Antioxidants and Atherosclerotic Heart Disease FH Epstein, MN Diaz, B Frei, JA Vita, JF Keaney	New England Journal of Medicine	1997
Advances in Molecular and Cell Biology KJ Clemetson	Advances in Molecular and Cell Biology	1997
Oxidized low-density lipoprotein stimulates endothelin-1 release and mRNA expression from rat mesangial cells MS Tan, YJ Lee, SJ Shin, JH Tsai	Journal of Laboratory and Clinical Medicine	1997
Non-specific inhibition by human lipoproteins of endothelium dependent relaxation in rat aorta may be attributed to lipoprotein phospholipids TV Lewis, AM Dart, JP Chin-Dusting	Cardiovascular Research	1997
Xanthine Oxidase Inhibition With Oxypurinol Improves Endothelial Vasodilator Function in Hypercholesterolemic but Not in Hypertensive Patients C Cardillo, CM Kilcoyne, RO Cannon, AA Quyyumi, JA Panza	Hypertension	1997
Vitamin C Reduces Cholesterol-Induced Microcirculatory Changes in Rabbits A Freyschuss, RJ Xiu, J Zhang, X Ying, U Diczfalusy, T Jogestrand, P Henriksson, I Björkhem	Arteriosclerosis, thrombosis, and vascular biology	1997
Vitamin C Improves Endothelial Dysfunction of Epicardial Coronary Arteries in Hypertensive Patients U Solzbach, B Hornig, M Jeserich, H Just	Circulation	1997
Mildly Oxidized Low-Density Lipoprotein Impairs Responses of Carotid but Not Basilar Artery in Rabbits C Napoli, R Paternò, FM Faraci, H Taguchi, A Postiglione, DD Heistad	Stroke; a journal of cerebral circulation	1997
Long-term Probucol Treatment Reverses the Severity of Myocardial Injury in Watanabe Heritable Hyperlipidemic Rabbits S Hoshida, N Yamashita, J Igarashi, K Aoki, T Kuzuya, M Hori	Arteriosclerosis, thrombosis, and vascular biology	1997
Hyperhomocyst(e)inemia Is Associated With Impaired Endothelium-Dependent Vasodilation in Humans A Tawakol, T Omland, M Gerhard, JT Wu, MA Creager	Circulation	1997
Endogenous Estrogen and Acetylcholine-Induced Vasodilation in Normotensive Women S Pinto, A Virdis, L Ghiadoni, GP Bernini, M Lombardo, F Petraglia, AR Genazzani, S Taddei, A Salvetti	Hypertension	1997
Single LDL Apheresis Improves Endothelium-Dependent Vasodilatation in Hypercholesterolemic Humans O Tamai, H Matsuoka, H Itabe, Y Wada, K Kohno, T Imaizumi	Circulation	1997
Vascular Superoxide Dismutase Deficiency Impairs Endothelial Vasodilator Function Through Direct Inactivation of Nitric Oxide and Increased Lipid Peroxidation SM Lynch, B Frei, JD Morrow, LJ Roberts, A Xu, T Jackson, R Reyna, LM Klevay, JA Vita, JF Keaney	Arteriosclerosis, thrombosis, and vascular biology	1997
Arterial Remodeling: A Critical Factor in Restenosis A Lafont, EJ Topol		1997
Clinical Research in Diabetes and Obesity B Draznin, R Rizza		1997
Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance HO Steinberg, H Chaker, R Leaming, A Johnson, G Brechtel, AD Baron	Journal of Clinical Investigation	1996
Vascular incorporation of alpha-tocopherol prevents endothelial dysfunction due to oxidized LDL by inhibiting protein kinase C stimulation JF Keaney, Y Guo, D Cunningham, GT Shwaery, A Xu, JA Vita	Journal of Clinical Investigation	1996
Effect of dietary fish oil supplementation on peroxidation of serum lipids in patients with non-insulin dependent diabetes mellitus LT McGrath, GM Brennan, JP Donnelly, GD Johnston, JR Hayes, GE McVeigh	Atherosclerosis	1996
The Antioxidant and Antiatherogenic Effects of MAK-4 In WHHL Rabbits JY Lee, AN Hanna, JA Lott, HM Sharma	The Journal of Alternative and Complementary Medicine	1996
Enhanced Antiproliferative Effect of Nitric Oxide in Cultured Smooth Muscle Cells from Diabetic Rats P Etienne, N Parés-Herbuté, L Monnier	Journal of Cardiovascular Pharmacology	1996
CLINICALLY RELEVANT DOSES AND BLOOD LEVELS PRODUCE EXPERIMENTAL CYCLOSPORINE NEPHROTOXICITY WHEN COMBINED WITH NITRIC OXIDE INHIBITION1 MP Gardner, DC Houghton, TF Andoh, J Lindsley, WM Bennett	Transplantation	1996
Nitric Oxide Metabolite Levels in Acute Vaso-occlusive Sickle-cell Crisis BL Lopez, J Barnett, SK Ballas, TA Christopher, L Davis-Moon, X Ma	Academic Emergency Medicine	1996
Cigarette smoke-modified low density lipoprotein impairs endothelium-dependent relaxation in isolated rabbit arteries S Kagota, Y Yamaguchi, K Shinozuka, YM Kwon, M Kunitomo	General Pharmacology: The Vascular System	1996
Alteration in the pulsatility index values of the internal carotid and middle cerebral arteries after suspension of postmenopausal hormone replacement therapy: A randomized crossover study Penotti, Farina, Castiglioni, Gaffuri, Barletta, Gabrielli, Vignali	American Journal of Obstetrics and Gynecology	1996
Reversal by high-density lipoprotein of the effect of oxidized low-density lipoprotein on nitric oxide synthase protein expression in human platelets JL Mehta, LY Chen	Journal of Laboratory and Clinical Medicine	1996
Monocyte-Induced Downregulation of Nitric Oxide Synthase in Cultured Aortic Endothelial Cells N Marczin, A Antonov, A Papapetropoulos, DH Munn, R Virmani, FD Kolodgie, R Gerrity, JD Catravas	Arteriosclerosis, thrombosis, and vascular biology	1996
Vitamin E Deficiency in Variant Angina K Miwa, Y Miyagi, A Igawa, K Nakagawa, H Inoue	Circulation	1996
Oxidized LDL Decreases l -Arginine Uptake and Nitric Oxide Synthase Protein Expression in Human Platelets: Relevance of the Effect of Oxidized LDL on Platelet Function LY Chen, P Mehta, JL Mehta	Circulation	1996
Endocrinology of the Vasculature JR Sowers		1996
Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide generation JF Keaney, A Xu, D Cunningham, T Jackson, B Frei, JA Vita	Journal of Clinical Investigation	1995
Susceptibility of plasma low density lipoprotein to cupric ion—induced peroxidation in patients with variant angina K Miwa, Y Miyagi, M Fujita	Journal of the American College of Cardiology	1995
Low-density lipoproteins inhibit histamine and NaNO2 relaxations of the coronary vasculature and reduce contractile function in isolated rat hearts GJ Harrison, LR Jordan, ML Selley, RJ Willis	Heart and Vessels	1995
Hyperlipidaemia, hypertension, and coronary heart disease GK Goode, JP Miller, AM Heagerty	The Lancet	1995
Effects of LDL on intracellular free calcium and nitric oxide-dependent cGMP formation in porcine endothelial cells U Pohl, N Heydari, J Galle	Atherosclerosis	1995
Interactions Between Endothelial Mediators RJ Gryglewski	Pharmacology & Toxicology	1995
Nitric Oxide RA Schroeder, PC Kuo	Anesthesia & Analgesia	1995
Enhanced renal perfusion improves function in severe nephrosis with focal segmental glomerulosclerosis P FUTRAKUL, N FUTRAKUL, V SITPRIJA	Nephrology	1995
Regulation of inducible nitric oxide synthase expression in rat mesangial cells and isolated glomeruli M Saura, S López, MR Puyol, DR Puyol, S Lamas	Kidney International	1995
Influence of chronic treatment with a nitric oxide donor on fatty streak development and reactivity of the rabbit aorta H Bult, GR de Meyer, AG Herman	British Journal of Pharmacology	1995
Nitric oxide. Novel biology with clinical relevance TR Billiar	Annals of Surgery	1995
Cardiovascular disease and nutrient antioxidants: Role of low‐density lipoprotein oxidation B Frei	Critical Reviews in Food Science and Nutrition	1995
Immunopharmacology of Free Radical Species C Rice-Evans	Immunopharmacology of Free Radical Species	1995
Oxidation of parenteral lipid emulsion by ambient and phototherapy lights: Potential toxicity of routine parenteral feeding J Neuzil, BA Darlow, TE Inder, KB Sluis, CC Winterbourn, R Stocker	The Journal of Pediatrics	1995
Thyronines and probucol inhibition of human capillary endothelial cell-induced low density lipoprotein oxidation AN Hanna, LC Titterington, LE Lantry, RE Stephens, HA Newman	Biochemical Pharmacology	1995
Reduction of nitric oxide synthase activity in human neutrophils by oxidized low-density lipoproteins JL Mehta, JL Bryant, P Mehta	Biochemical Pharmacology	1995
Chronic Administration of the Nitric Oxide Synthase Inhibitor, L-NAME, Increases Circulating Endothelin Levels in Guinea Pigs MJ Miller, UK Munshi, XJ Zhang, H Sadowska-Krowicka, P Savage, JL Kakkis, S Eloby-Childress, DA Clark, SA Bustamante, AY Jeng	Endothelium : journal of endothelial cell research	1995
Oxidized Low-density Lipoprotein Decreases the Expression of Endothelial Nitric Oxide Synthase JK Liao, WS Shin, WY Lee, SL Clark	The Journal of biological chemistry	1995
Antioxidants and Cardiovascular Disease KR Bruckdorfer		1995
Transcriptional Induction of Endothelial Nitric Oxide Synthase Type III by Lysophosphatidylcholine A Zembowicz, J Tang, KK Wu	The Journal of biological chemistry	1995
Effects of magnesium on nitric oxide synthase activity in endothelial cells AB Howard, RW Alexander, WR Taylor	American journal of physiology. Cell physiology	1995
Formation of F 2 -Isoprostanes During Oxidation of Human Low-Density Lipoprotein and Plasma by Peroxynitrite KP Moore, V Darley-Usmar, J Morrow, LJ Roberts	Circulation research	1995
Achieving optimal reperfusion without adjunctive antithrombotic therapy: Novel thrombolytic dosing strategies RC Becker	Journal of Thrombosis and Thrombolysis	1995
Human Atherosclerotic Plaque Contains Both Oxidized Lipids and Relatively Large Amounts of α-Tocopherol and Ascorbate C Suarna, RT Dean, J May, R Stocker	Arteriosclerosis, thrombosis, and vascular biology	1995
Impairment of Endothelium-Dependent Dilation in Rabbit Renal Arteries by Oxidized Lipoprotein(a): Role of Oxygen-Derived Radicals J Galle, J Bengen, P Schollmeyer, C Wanner	Circulation	1995
Atherosclerosis, oxidative stress, and antioxidant protection in endothelium-derived relaxing factor action JF Keaney, JA Vita	Progress in Cardiovascular Diseases	1995
Mediators in the Cardiovascular System: Regional Ischemia K Schrör, CR Pace-Asciak		1995
Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response PA Craven, RK Studer, FR DeRubertis	Journal of Clinical Investigation	1994
Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits JF Keaney, JM Gaziano, A Xu, B Frei, J Curran-Celentano, GT Shwaery, J Loscalzo, JA Vita	Journal of Clinical Investigation	1994
The antioxidant butylated hydroxytoluene prevents early cholesterol-induced microcirculatory changes in rabbits RJ Xiu, A Freyschuss, X Ying, L Berglund, P Henriksson, I Björkhem	Journal of Clinical Investigation	1994
Nitric Oxide and the Cardiovascular System G Welch, J Loscalto	Journal of Cardiac Surgery	1994
Enhanced LDL oxidation by murine macrophage foam cells and their failure to secrete nitric oxide EJ Bolton, W Jessup, KK Stanley, RT Dean	Atherosclerosis	1994
Why are low-density lipoproteins atherogenic? SG Young, S Parthasarathy	The Western journal of medicine	1994
Coronary atherosclerotic wall thickening and vascular reactivity in humans. Elevated high-density lipoprotein levels ameliorate abnormal vasoconstriction in early atherosclerosis AM Zeiher, V Schächlinger, SH Hohnloser, B Saurbier, H Just	Circulation	1994
Physical and chemical interactions between nitric oxide and nitroxides RJ Singh, N Hogg, HS Mchaourab, B Kalyanaraman	Biochimica et Biophysica Acta (BBA) - General Subjects	1994
Natural Antioxidants in Human Health and Disease M Levine, KR Dhariwal, Y Wang, JB Park, RW Welch	Natural Antioxidants in Human Health and Disease	1994
Lipid Peroxidation in Pregnancy SW Walsh	Hypertension in Pregnancy	1994
Free Radical Chemistry of Nitric Oxide B Freeman	Chest	1994
Inhibition of inducible nitric oxide synthase in macrophages by oxidized low-density lipoproteins X Yang, B Cai, RR Sciacca, PJ Cannon	Circulation research	1994
Oxidized lipoproteins inhibit endothelium-dependent vasodilation. Effects of pressure and high-density lipoprotein J Galle, M Ochslen, P Schollmeyer, C Wanner	Hypertension	1994
17 beta-estradiol preserves endothelial vasodilator function and limits low-density lipoprotein oxidation in hypercholesterolemic swine JF Keaney, GT Shwaery, A Xu, RJ Nicolosi, J Loscalzo, TL Foxall, JA Vita	Circulation	1994
The basal and stimulated release of the endothelium-derived relaxing factor from isolated pig coronary arteries does not interfere with the vascular release of superoxide RP Brandes, A Dwenger, A Mgge	Naunyn-Schmiedeberg's Archives of Pharmacology	1994
Probucol inhibits mononuclear cell adhesion to vascular endothelium in the cholesterol-fed rabbit GA Ferns, L Forster, A Stewart-Lee, J Nourooz-Zadeh, EE Änggård	Atherosclerosis	1993
Stickoxid-freisetzende Substanzen und Inhibitoren der NO-Synthase R Henning	Nachrichten aus Chemie, Technik und Laboratorium	1993
Stimulation of endothelin-1 release by low density and very low density lipoproteins in cultured human endothelial cells T Horio, M Kohno, K Yasunari, K Murakawa, K Yokokawa, M Ikeda, T Fukui, T Takeda	Atherosclerosis	1993
Autoinhibition of murine macrophage-mediated oxidation of low-density lipoprotein by nitric oxide synthesis W Jessup, RT Dean	Atherosclerosis	1993
Oxidized low density lipoprotein inhibits the migration of aortic endothelial cells in vitro G Murugesan, GM Chisolm, PL Fox	The Journal of Cell Biology	1993
Dietary antioxidants preserve endothelium-dependent vessel relaxation in cholesterol-fed rabbits JF Keaney, JM Gaziano, A Xu, B Frei, J Curran-Celentano, GT Shwaery, J Loscalzo, JA Vita	Proceedings of the National Academy of Sciences	1993
The role of endothelial cells on the alterations in vascular reactivity induced by insulin-dependent diabetes mellitus: Effects of insulin treatment Ç Karasu, VM Altan	General Pharmacology: The Vascular System	1993
Inhibition of low-density lipoprotein oxidation by nitric oxide Potential role in atherogenesis N Hogg, B Kalyanaraman, J Joseph, A Struck, S Parthasarathy	FEBS Letters	1993
Dissent What is truth said Pontius Pilate and would not wait for an answer: A biological reply to Dr Stehbens AD Sniderman	Journal of Clinical Epidemiology	1993
Responsiveness to bradykinin in veins of hypercholesterolemic humans GV Bedarida, E Bushell, WE Haefeli, TF Blaschke, BB Hoffman	Circulation	1993
Hypercholesterolemia is associated with a reduced response of smooth muscle guanylyl cyclase to nitrovasodilators K Schmidt, P Klatt, B Mayer	Arteriosclerosis Thrombosis and Vascular Biology	1993
Metabolism and excretion of nitric oxide in humans. An experimental and clinical study A Wennmalm, G Benthin, A Edlund, L Jungersten, N Kieler-Jensen, S Lundin, UN Westfelt, AS Petersson, F Waagstein	Circulation research	1993
Hypercholesterolemia promotes endothelial dysfunction in vitamin E- and selenium-deficient rats L Raij, J Nagy, K Coffee, EG DeMaster	Hypertension	1993
Physical conditioning can modulate endothelium-dependent vasorelaxation in rabbits HI Chen, HT Li	Arteriosclerosis Thrombosis and Vascular Biology	1993
Growth Factors and the Cardiovascular System P Cummins		1993
Hypercholesterolaemia alters arterial and blood factors related to atherosclerosis in hypertension J Levenson, MD Pino, M Razavian, I Merli, V Filitti, A Simon	Atherosclerosis	1992
Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform S Lamas, PA Marsden, GK Li, P Tempst, T Michel	Proceedings of the National Academy of Sciences	1992
Low density lipoprotein inhibits accumulation of nitrites in murine brain endothelial cell cultures M Bereta, J Bereta, S Cohen, MC Cohen	Biochemical and Biophysical Research Communications	1992
Endothelial vasomotor regulation in health and disease NR Searle, P Sahab	Canadian Journal of Anesthesia/Journal canadien d'anesthésie	1992
Subcellular Biochemistry DB Roodyn	Subcellular Biochemistry	1981
Arteriosclerosis R Gubner, HE Ungerleider	The American Journal of Medicine	1949

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