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T J Gregory, … , C Crim, T M Hyers
Published December 1, 1991
Citation Information: J Clin Invest. 1991;88(6):1976-1981. https://doi.org/10.1172/JCI115523.
Citation Information: J Clin Invest. 1991;88(6):1976-1981. https://doi.org/10.1172/JCI115523.
Abstract
Acute Respiratory Distress Syndrome (ARDS) is characterized by lung injury and damage to the alveolar type II cells. This study sought to determine if endogenous surfactant is altered in ARDS. Bronchoalveolar lavage was performed in patients at-risk to develop ARDS (AR, n = 20), with ARDS (A, n = 66) and in normal subjects (N, n = 29). The crude surfactant pellet was analyzed for total phospholipids (PL), individual phospholipids, SP-A, SP-B, and minimum surface tension (STmin). PL was decreased in both AR and A (3.48 +/- 0.61 and 2.47 +/- 0.40 mumol/ml, respectively) compared to N (7.99 +/- 0.60 mumol/ml). Phosphatidylcholine was decreased in A (62.64 +/- 2.20% PL) compared to N (76.27 +/- 2.05% PL). Phosphatidylglycerol was 11.58 +/- 1.21% PL in N and was decreased to 6.48 +/- 1.43% PL in A. SP-A was 123.64 +/- 20.66 micrograms/ml in N and was decreased to 49.28 +/- 21.68 micrograms/ml in AR and to 29.88 +/- 8.49 micrograms/ml in A. SP-B was 1.28 +/- 0.33 micrograms/ml in N and was decreased to 0.57 +/- 0.24 micrograms/ml in A. STmin was increased in AR (15.1 +/- 2.53 dyn/cm) and A (29.04 +/- 2.05 dyn/cm) compared to N (7.44 +/- 1.61 dyn/cm). These data demonstrate that the chemical composition and functional activity of surfactant is altered in ARDS. Several of these alterations also occur in AR, suggesting that these abnormalities occur early in the disease process.
Authors
T J Gregory, W J Longmore, M A Moxley, J A Whitsett, C R Reed, A A Fowler 3rd, L D Hudson, R J Maunder, C Crim, T M Hyers
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R Terjung |
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R Terjung |
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R Terjung |
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Biomarkers of acute lung injury: worth their salt?
AG Proudfoot, M Hind, MJ Griffiths |
BMC Medicine | 2011 |
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Thyroid transcription factor-1 (TTF-1) gene: identification of ZBP-89, Sp1, and TTF-1 sites in the promoter and regulation by TNF-α in lung epithelial cells
A Das, S Acharya, KR Gottipati, JB McKnight, H Chandru, JL Alcorn, V Boggaram |
American journal of physiology. Lung cellular and molecular physiology | 2011 |
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Disaturated-phosphatidylcholine and Surfactant protein-B turnover in human acute lung injury and in control patients
M Simonato, A Baritussio, C Ori, L Vedovelli, S Rossi, LD Massara, S Rizzi, VP Carnielli, PE Cogo |
Respiratory Research | 2011 |
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The influence of genetic variation in surfactant protein B on severe lung injury in African American children*
MK Dahmer, P OʼCain, PP Patwari, P Simpson, SH Li, N Halligan, MW Quasney |
Critical Care Medicine | 2011 |
|
Surfactant Therapy of ALI and ARDS
K Raghavendran, D Willson, RH Notter |
Critical Care Clinics | 2011 |
|
<i>In vivo</i> effect of surfactant on inflammatory cytokines during endotoxin-induced lung injury in rodents
N Mittal, SN Sanyal |
Journal of Immunotoxicology | 2011 |
|
Synthetic liposomes are protective from bleomycin-induced lung toxicity
WM Gwinn, MC Kapita, PM Wang, MF Cesta, WJ Martin |
American journal of physiology. Lung cellular and molecular physiology | 2011 |
|
Thyroid transcription factor-1 (TTF-1) gene: identification of ZBP-89, Sp1, and TTF-1 sites in the promoter and regulation by TNF-α in lung epithelial cells
A Das, S Acharya, KR Gottipati, JB McKnight, H Chandru, JL Alcorn, V Boggaram |
American journal of physiology. Lung cellular and molecular physiology | 2011 |
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LPCAT1 Regulates Surfactant Phospholipid Synthesis and is Required for Transitioning to Air Breathing in Mice
James Bridges, Machiko Ikegami, Lauren Brilli, Xueni Chen, Robert Mason, John Shannon |
Journal of Clinical Investigation | 2010 |
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Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice
V Besnard, Y Matsuzaki, J Clark, Y Xu, SE Wert, M Ikegami, MT Stahlman, TE Weaver, AN Hunt, AD Postle, JA Whitsett |
American journal of physiology. Lung cellular and molecular physiology | 2010 |
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Genetic Abnormalities of Surfactant Metabolism
Nogee LM, Wert SE |
2010 | |
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Cycloxygenase Inhibition Enhances the Effects of Surfactant Therapy in Endotoxin-Induced Rat Model of ARDS
N Mittal, SN Sanyal |
Inflammation | 2010 |
|
Pharmacological treatments for acute respiratory distress syndrome
AJ Frank, BT Thompson |
Current Opinion in Critical Care | 2010 |
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Nonventilatory strategies for patients with life-threatening 2009 H1N1 influenza and severe respiratory failure
LM Napolitano, PK Park, K Raghavendran, RH Bartlett |
Critical Care Medicine | 2010 |
|
Dry powder aerosolization of a recombinant surfactant protein-C–based surfactant for inhalative treatment of the acutely inflamed lung*
C Ruppert, T Kuchenbuch, M Boensch, S Schmidt, U Mathes, V Hillebrand, I Henneke, P Markart, I Reiss, RT Schermuly, W Seeger, A Günther |
Critical Care Medicine | 2010 |
|
High-frequency oscillation and surfactant treatment in an acid aspiration model
AJ Aspros, CG Coto, JF Lewis, RA Veldhuizen |
Canadian Journal of Physiology and Pharmacology | 2010 |
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Improved gas exchange and survival after KL-4 surfactant in newborn pigs with severe acute lung injury
AM Zimmermann, KD Roberts, AL Lampland, PA Meyers, CT Worwa, B Plumm, MC Pacheco, MR Wolfson, MC Mammel |
Pediatric Pulmonology | 2010 |
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Murray and Nadel's Textbook of Respiratory Medicine
MA Matthay, TR Martin |
Murray and Nadel's Textbook of Respiratory Medicine | 2010 |
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Transcriptional regulation of SP-B gene expression by nitric oxide in H441 lung epithelial cells
V Boggaram, H Chandru, KR Gottipati, V Thakur, A Das, K Berhane |
American journal of physiology. Lung cellular and molecular physiology | 2010 |
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Free Volume Theory Applied to Lateral Diffusion in Langmuir Monolayers: Atomistic Simulations for a Protein-Free Model of Lung Surfactant
M Javanainen, L Monticelli, JB de la Serna, I Vattulainen |
Langmuir | 2010 |
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Effect of a PEGylated Lipid on the Dispersion Stability and Dynamic Surface Tension of Aqueous DPPC and on the Interactions with Albumin
Y Park, EI Franses |
Langmuir | 2010 |
|
Pulmonary surfactant surface tension influences alveolar capillary shape and oxygenation
M Ikegami, TE Weaver, SN Grant, JA Whitsett |
American journal of respiratory cell and molecular biology | 2009 |
|
C/EBP{alpha} is required for pulmonary cytoprotection during hyperoxia
Y Xu, C Saegusa, A Schehr, S Grant, JA Whitsett, M Ikegami |
American journal of physiology. Lung cellular and molecular physiology | 2009 |
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Role of Lung Surfactant in Respiratory Disease: Current Knowledge in Large Animal Medicine
U Christmann, VA Buechner-Maxwell, SG Witonsky, RD Hite |
Journal of Veterinary Internal Medicine | 2009 |
|
Exogenous Natural Surfactant for Treatment of Acute Lung Injury and the Acute Respiratory Distress Syndrome
J Kesecioglu, R Beale, TE Stewart, GP Findlay, JJ Rouby, L Holzapfel, P Bruins, EJ Steenken, OK Jeppesen, B Lachmann |
American journal of respiratory and critical care medicine | 2009 |
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Phospholipase A2 subclasses in acute respiratory distress syndrome
E Kitsiouli, G Nakos, ME Lekka |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2009 |
|
ELEVATED ENDOGENOUS SURFACTANT REDUCES INFLAMMATION IN AN ACUTE LUNG INJURY MODEL
MG Walker, JM Tessolini, L McCaig, LJ Yao, JF Lewis, RA Veldhuizen |
Experimental Lung Research | 2009 |
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Variable stretch pattern enhances surfactant secretion in alveolar type II cells in culture
SP Arold, E Bartolák-Suki, B Suki |
American journal of physiology. Lung cellular and molecular physiology | 2009 |
|
C/EBPα is required for pulmonary cytoprotection during hyperoxia
Y Xu, C Saegusa, A Schehr, S Grant, JA Whitsett, M Ikegami |
American journal of physiology. Lung cellular and molecular physiology | 2009 |
|
Intensive Care Medicine
JL Vincent |
Intensive Care Medicine | 2009 |
|
Influence of Age on Surfactant Isolated from Healthy Horses Maintained on Pasture
U Christmann, RD Hite, SG Witonsky, F Elvinger, SR Werre, CD Thatcher, RH Tan, VA Buechner-Maxwell |
Journal of Veterinary Internal Medicine | 2009 |
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Competitive Adsorption: A Physical Model for Lung Surfactant Inactivation
JG Fernsler, JA Zasadzinski |
Langmuir | 2009 |
|
Genetic Polymorphisms in Critical Care and Illness
Dahmer MK, Quasney MW |
2008 | |
|
Surfactant protein-B polymorphisms and mortality in the acute respiratory distress syndrome*
PF Currier, MN Gong, R Zhai, LJ Pothier, PD Boyce, L Xu, CL Yu, BT Thompson, DC Christiani |
Critical Care Medicine | 2008 |
|
Bronchoscopic Surfactant Administration in Pediatric Patients with Persistent Lobar Atelectasis
MF Krause, P Bismarck, HC Oppermann, T Ankermann |
Respiration | 2008 |
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Current perspectives in pulmonary surfactant — Inhibition, enhancement and evaluation
YY Zuo, RA Veldhuizen, AW Neumann, NO Petersen, F Possmayer |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 2008 |
|
Effects of eicosane, a component of nanoparticles in diesel exhaust, on surface activity of pulmonary surfactant monolayers
S Kanno, A Furuyama, S Hirano |
Archives of Toxicology | 2008 |
|
Secretory phospholipase A2 and neonatal respiratory distress: pilot study on broncho-alveolar lavage
D Luca, S Baroni, G Vento, M Piastra, D Pietrini, F Romitelli, E Capoluongo, C Romagnoli, G Conti, E Zecca |
Intensive Care Medicine | 2008 |
|
The effects of long-term conventional mechanical ventilation on the lungs of adult rats*
TC Bailey, AA Maruscak, EL Martin, AR Forbes, A Petersen, LA McCaig, LJ Yao, JF Lewis, RA Veldhuizen |
Critical Care Medicine | 2008 |
|
EFFECT OF N-ACETYL-l-CYSTEINE ON LUNG ISCHAEMIA REPERFUSION INJURY IN A PORCINE EXPERIMENTAL MODEL
TP Chamogeorgakis, GG Kostopanagiotou, CA Kalimeris, GI Kabouroglou, AN Kourtesis, CI Routsi, CC Dima, IK Toumpoulis |
ANZ Journal of Surgery | 2008 |
|
Pharmacotherapy of acute lung injury and acute respiratory distress syndrome
K Raghavendran, GS Pryhuber, PR Chess, BA Davidson, PR Knight, RH Notter |
Current medicinal chemistry | 2008 |
|
Surfactant for Pediatric Acute Lung Injury
DF Willson, PR Chess, RH Notter |
Pediatric Clinics of North America | 2008 |
|
Pneumoproteins as markers of paraquat lung injury: A clinical case
P Hantson, B Weynand, I Doyle, A Bernand, C Hermans |
Journal of Forensic and Legal Medicine | 2008 |
|
Mechanisms of Acute Lung Injury and Repair
KC Doerschug, GW Hunninghake |
Pediatric Respiratory Medicine | 2008 |
|
Surfactant Therapy
D Gommers, B Lachmann |
Mechanical Ventilation | 2008 |
|
Blunt Thoracic Trauma
A Reske, D Schreiter |
Mechanical Ventilation | 2008 |
|
The Newborn Lung
JL Aschner, CD Fike |
The Newborn Lung | 2008 |
|
STAT-3 regulates surfactant phospholipid homeostasis in normal lung and during endotoxin-mediated lung injury
M Ikegami, A Falcone, JA Whitsett |
Journal of applied physiology | 2008 |
|
The Respiratory Tract in Pediatric Critical Illness and Injury
DS Wheeler, HR Wong, TP Shanley |
2008 | |
|
Yearbook of Intensive Care and Emergency Medicine
JL Vincent |
2008 | |
|
Molecular Pathology of Lung Diseases
DS Zander, HH Popper, J Jagirdar, AK Haque, PT Cagle, R Barrios |
2008 | |
|
Science and Practice of Pediatric Critical Care Medicine
DS Wheeler, HR Wong, TP Shanley |
2008 | |
|
Secretory phospholipase A2 and neonatal respiratory distress: pilot study on broncho-alveolar lavage
DD Luca, S Baroni, G Vento, M Piastra, D Pietrini, F Romitelli, E Capoluongo, C Romagnoli, G Conti, E Zecca |
Intensive Care Medicine | 2008 |
|
Pulmonary Surfactant: Biology and Therapy
Willson DF, Chess PR, Wang Z, Notter RH |
2008 | |
|
Surfactant protein A and surfactant protein D variation in pulmonary disease
GL Sorensen, S Husby, U Holmskov |
Immunobiology | 2007 |
|
Surfactant degradation activity in bronchoalveolar lavage fluid from guinea pigs challenged with antigen
M ABO, K KURASHIMA, M FUJIMURA, S MYOU, S NAKAO, K TASHIRO, T KOBAYASHI |
Respirology | 2007 |
|
Surfactant “fortification” by topical inhibition of nuclear factor-κB activity in a newborn piglet lavage model*
P Bismarck, K Klemm, CF Wistädt, S Winoto-Morbach, U Uhlig, S Schütze, S Uhlig, B Lachmann, MF Krause |
Critical Care Medicine | 2007 |
|
Time-dependent changes in pulmonary surfactant function and composition in acute respiratory distress syndrome due to pneumonia or aspiration
R Schmidt, P Markart, C Ruppert, M Wygrecka, T Kuchenbuch, D Walmrath, W Seeger, A Guenther |
Respiratory Research | 2007 |
|
Integrin beta6 mediates phospholipid and collectin homeostasis by activation of latent TGF-beta1
LL Koth, B Alex, S Hawgood, MA Nead, D Sheppard, DJ Erle, DG Morris |
American journal of respiratory cell and molecular biology | 2007 |
|
Interactions of serum with lung surfactant extract in the bronchiolar and alveolar airway models
K Nag, A Hillier, K Parsons, MF Garcia |
Respiratory Physiology & Neurobiology | 2007 |
|
Protective role of macrophages in noninflammatory lung injury caused by selective ablation of alveolar epithelial type II Cells
Y Miyake, H Kaise, KI Isono, H Koseki, K Kohno, M Tanaka |
Journal of immunology (Baltimore, Md. : 1950) | 2007 |
|
Mechanisms of Sepsis-Induced Organ Dysfunction and Recovery
E Abraham, M Singer |
2007 | |
|
Phenotypic Heterogeneity in Lung Capillary and Extra-Alveolar Endothelial Cells. Increased Extra-Alveolar Endothelial Permeability is Sufficient to Decrease Compliance
K Lowe, D Alvarez, J King, T Stevens |
The Journal of surgical research | 2007 |
|
(K)eine Surfactant-Therapie bei Patienten mit „acute respiratory distress syndrome“?: Bedeutung einer Surfactant-Substitutionstherapie in der Behandlung des akuten Lungenversagens
S Lauer, LG Fischer, HD Stubbe, HV Aken, M Westphal |
Der Anaesthesist | 2006 |
|
Surface tension influences cell shape and phagocytosis in alveolar macrophages
H Akei |
American journal of physiology. Lung cellular and molecular physiology | 2006 |
|
Exogenous surfactant therapy for ARDS
A Maruscak, JF Lewis |
Expert Opinion on Investigational Drugs | 2006 |
|
Pulmonary surfactant in patients with Pneumocystis pneumonia and acquired immunodeficiency syndrome
R Schmidt, P Markart, C Ruppert, B Temmesfeld, R Nass, J Lohmeyer, W Seeger, A G??nther |
Critical Care Medicine | 2006 |
|
Small-dose perfluorocarbon reduces the recruitment pressure needed to open surfactant-deficient atelectatic lungs
RJ Houmes, RA Lachmann, JJ Haitsma, B Lachmann |
Acta Anaesthesiologica Scandinavica | 2006 |
|
(K)eine Surfactant-Therapie bei Patienten mit „acute respiratory distress syndrome“?
S Lauer, LG Fischer, HD Stubbe, H Aken, M Westphal |
Der Anaesthesist | 2006 |
|
Intrapulmonary application of a 5-lipoxygenase inhibitor using surfactant as a carrier reduces lung edema in a piglet model of airway lavage
T Ankermann, A Reisner, T Wiemann, H Koehler, M Krams, MF Krause |
Pediatric Pulmonology | 2006 |
|
KL4-surfactant prevents hyperoxic and LPS-induced lung injury in mice
P Kinniry, J Pick, S Stephens, D Jain, CC Solomides, R Niven, R Segal, M Christofidou-Solomidou |
Pediatric Pulmonology | 2006 |
|
Acute Lung Injury: An Indicator of Serious Systemic Illness
JP Kepros, JM Gauvin, DN Reed, J Osuch |
Current Surgery | 2006 |
|
Probing perturbation of bovine lung surfactant extracts by albumin using DSC and 2H-NMR
K Nag, KM Keough, MR Morrow |
Biophysical Journal | 2006 |
|
Mechanisms of Acute Lung Injury/Acute Respiratory Distress Syndrome
BT Suratt, PE Parsons |
Clinics in Chest Medicine | 2006 |
|
The surface activity of pulmonary surfactant from diving mammals
NJ Miller, CB Daniels, S Schürch, WM Schoel, S Orgeig |
Respiratory Physiology & Neurobiology | 2006 |
|
Kendig's Disorders of the Respiratory Tract in Children
SH Abman, JM Davis |
Kendig's Disorders of the Respiratory Tract in Children | 2006 |
|
INTERLEUKIN-6 HAS NO EFFECT ON SURFACTANT OR LUNG FUNCTION IN DIFFERENT LUNG INSULTS
T Nakamura, BZ Moyer, RA Veldhuizen, JF Lewis |
Experimental Lung Research | 2006 |
|
Encyclopedia of Respiratory Medicine
PD Wagner |
Encyclopedia of Respiratory Medicine | 2006 |
|
Functional ambivalence of phospholipid hydrolysis in lung: Implications for surfactant alteration and bacterial killing
L Touqui |
Journal of Organ Dysfunction | 2006 |
|
Ceramide decreases surfactant protein B gene expression via downregulation of TTF-1 DNA binding activity
L Sparkman, H Chandru, V Boggaram |
American journal of physiology. Lung cellular and molecular physiology | 2006 |
|
Time course of lung parenchyma remodeling in pulmonary and extrapulmonary acute lung injury
FB Santos, LK Nagato, NM Boechem, EM Negri, A Guimarães, VL Capelozzi, DS Faffe, WA Zin, PR Rocco |
Journal of applied physiology | 2006 |
|
Physiological effects of oxidized exogenous surfactant in vivo: effects of high tidal volume and surfactant protein A
TC Bailey, AA Maruscak, A Petersen, S White, JF Lewis, RA Veldhuizen |
American journal of physiology. Lung cellular and molecular physiology | 2006 |
|
Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management
MA Matthay, GA Zimmerman |
American journal of respiratory cell and molecular biology | 2005 |
|
TGF- perturbs surfactant homeostasis in vivo
M Ikegami |
American journal of physiology. Lung cellular and molecular physiology | 2005 |
|
Surfactant Proteins in Innate Host Defense of the Lung
JA Whitsett |
Neonatology | 2005 |
|
Reversibility of lung inflammation caused by SP-B deficiency
M Ikegami |
American journal of physiology. Lung cellular and molecular physiology | 2005 |
|
Genetic polymorphisms in sepsis
MK Dahmer, A Randolph, S Vitali, MW Quasney |
Pediatric Critical Care Medicine | 2005 |
|
Ischemic and Endotoxin Pre-Conditioning Reduce Lung Reperfusion Injury-Induced Surfactant Alterations
P Markart, R Schmidt, C Ruppert, C Höres, RE Silber, J Börgermann, A Günther, I Friedrich |
The Journal of Heart and Lung Transplantation | 2005 |
|
Topical inhibition of nuclear factor-??B enhances reduction in lung edema by surfactant in a piglet model of airway lavage
T Ankermann, A Reisner, T Wiemann, M Krams, H K??hler, MF Krause |
Critical Care Medicine | 2005 |
|
Evolution of treatments for patients with acute lung injury
AM Esper, GS Martin |
Expert Opinion on Investigational Drugs | 2005 |
|
Lysophospholipid and fatty acid inhibition of pulmonary surfactant: Non-enzymatic models of phospholipase A2 surfactant hydrolysis
RD Hite, MC Seeds, RB Jacinto, BL Grier, BM Waite, DA Bass |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 2005 |
|
Serum biomarkers in acute respiratory distress syndrome an ailing prognosticator
A Tzouvelekis, I Pneumatikos, D Bouros |
Respiratory Research | 2005 |
|
Critical structure-function determinants within the N-terminal region of pulmonary surfactant protein SP-B
AG Serrano, M Ryan, TE Weaver, J Pérez-Gil |
Biophysical Journal | 2005 |
|
Upregulation of aldose reductase by homocysteine in type II alveolar epithelial cells
H Jiang, XF Wang, L Fang, C Tang, Y Zhu, X Wang |
Biochemical and Biophysical Research Communications | 2005 |
|
Surfactant reduces extravascular lung water and invasion of polymorphonuclear leukocytes into the lung in a piglet model of airway lavage
MF Krause, T Wiemann, A Reisner, M Orlowska-Volk, H Köhler, T Ankermann |
Pulmonary Pharmacology & Therapeutics | 2005 |
|
Surfactant phospholipid changes after antigen challenge: a role for phosphatidylglycerol in dysfunction
RD Hite, MC Seeds, DL Bowton, BL Grier, AM Safta, R Balkrishnan, BM Waite, DA Bass |
American journal of physiology. Lung cellular and molecular physiology | 2005 |
|
Pulmonary and extrapulmonary acute lung injury: inflammatory and ultrastructural analyses
SL Menezes, PT Bozza, HC Neto, AP Laranjeira, EM Negri, VL Capelozzi, WA Zin, PR Rocco |
Journal of applied physiology | 2005 |
|
Yearbook of Intensive Care and Emergency Medicine 2005
JL Vincent |
2005 | |
|
Surfactant metabolism: factors affecting lipid uptake in vivo and in vitro
Poelma DL, Van Iwaarden JF, Lachmann B |
2005 | |
|
Stat-3 is Required for Pulmonary Homeostasis During Hyperoxia
Isamu Hokuto, Machiko Ikegami, Mitsuhiro Yoshida, Kiyoshi Takeda, Shizuo Akira, Anne-Karina T. Perl, William M. Hull, Susan E. Wert, Jeffrey A. Whitsett |
Journal of Clinical Investigation | 2004 |
|
Nitric oxide synthase-2 down-regulates surfactant protein-B expression and enhances endotoxin-induced lung injury in mice
RM Baron, IM Carvajal, LE Fredenburgh, X Liu, Y Porrata, ML Cullivan, KJ Haley, LA Sonna, GT de Sanctis, EP Ingenito, MA Perrella |
The FASEB Journal | 2004 |
|
Foxa2 is required for transition to air breathing at birth
H Wan, Y Xu, M Ikegami, MT Stahlman, KH Kaestner, SL Ang, JA Whitsett |
Proceedings of the National Academy of Sciences | 2004 |
|
Stat-3 is required for pulmonary homeostasis during hyperoxia
Hokuto I, Ikegami M, Yoshida M, Takeda K, Akira S, Perl AK, Hull WM, Wert SE, Whitsett JA |
Journal of Clinical Investigation | 2004 |
|
Non-Ventilatory–Based Strategies in the Management of Acute Respiratory Distress Syndrome
Y Klein, L Blackbourne, ES Barquist |
The Journal of Trauma: Injury, Infection, and Critical Care | 2004 |
|
Changes in pulmonary surfactant function and composition in bleomycin-induced pneumonitis and fibrosis
R Schmidt, C Ruppert, P Markart, N Lübke, L Ermert, N Weissmann, A Breithecker, M Ermert, W Seeger, A Günther |
Toxicology and Applied Pharmacology | 2004 |
|
Ventilation and oxygen: Just what the doctor ordered. . .Unfortunately*
J Lewis, R Veldhuizen |
Critical Care Medicine | 2004 |
|
Association between surfactant protein B + 1580 polymorphism and the risk of respiratory failure in adults with community-acquired pneumonia*
MW Quasney, GW Waterer, MK Dahmer, GK Kron, Q Zhang, LA Kessler, RG Wunderink |
Critical Care Medicine | 2004 |
|
Time course of respiratory mechanics and pulmonary structural remodelling in acute lung injury
PR Rocco, LD Facchinetti, HC Ferreira, EM Negri, VL Capelozzi, DS Faffe, WA Zin |
Respiratory Physiology & Neurobiology | 2004 |
|
Acute lung injury and acute respiratory distress syndrome in pregnancy
VD Bandi, U Munnur, MA Matthay |
Critical Care Clinics | 2004 |
|
Dysfunction of Pulmonary Surfactant in Chronically Ventilated Premature Infants
JD Merrill, RA Ballard, A Cnaan, AM Hibbs, RI Godinez, MH Godinez, WE Truog, PL Ballard |
Pediatric Research | 2004 |
|
The Lung
KH Albertine, TJ Psysher |
The Lung | 2004 |
|
Functional Genomics of Lung Disease
JA Whitsett, CJ Bachurski, KC Barnes, PA Bunn, LM Case, DN Cook, D Crooks, MW Duncan, L Dwyer-Nield, RC Elston, MB Fessler, WA Franklin, N Friedman, JG Garcia, MW Geraci, C Glasgow, SW Glasser, WD Hardie, LM Henning, GL Johnson, K Kawkitinarong, RL Keith, TR Korfhagen, GD Leikauf, SB Liggett, KC Malcolm, AM Malkinson, TJ Mariani, SA McDowell, DW McGraw, M Medvedovic, J Moss, LM Nogee, S Nonas, G Pacheco-Rodriguez, LJ Palmer, DG Peters, DR Prows, S Redline, A Regev, MA Sartor, DA Schwartz, EK Silverman, WK Steagall, RS Stearman, A Taveira-DaSilva, JW Tichelaar, CR Tomlinson, K Tsukada, TE Weaver, SE Wert, SC Wesselkamper, GS Worthen, Y Xu, L Zerbe, Y Zhang, Y Zhang, AM Choi, N Kaminski |
American journal of respiratory cell and molecular biology | 2004 |
|
Les déficits secondaires en surfactant
B Escande, P Kuhn, S Rivera, J Messer |
Archives de Pédiatrie | 2004 |
|
Polymorphism in the Surfactant Protein-B Gene, Gender, and the Risk of Direct Pulmonary Injury and ARDS
MN Gong, Z Wei, LL Xu, DP Miller, BT Thompson, DC Christiani |
Chest | 2004 |
|
In vivo clearance of surfactant lipids during acute pulmonary inflammation
JL Malloy, JR Wright |
Respiratory Research | 2004 |
|
Surfactant function in children with chronic airway inflammation
A Braun, M Steinecker, S Schumacher, M Griese |
Journal of applied physiology | 2004 |
|
Tissue heterogeneity in the mouse lung: effects of elastase treatment
S Ito, EP Ingenito, SP Arold, H Parameswaran, NT Tgavalekos, KR Lutchen, B Suki |
Journal of applied physiology | 2004 |
|
Distinct effects of SP-B and SP-C on the uptake of surfactant-like liposomes by alveolar cells in vivo and in vitro
DL Poelma, LJ Zimmermann, WA van Cappellen, JJ Haitsma, B Lachmann, JF van Iwaarden |
American journal of physiology. Lung cellular and molecular physiology | 2004 |
|
Perioperative and Critical Care Medicine
A Gullo, G Berlot, U Lucangelo, T Pellis |
2004 | |
|
Pulmonary Biology in Health and Disease
EE Bittar |
2004 | |
|
Elevation of lung surfactant phosphatidylcholine in mouse models of Sandhoff and of Niemann-Pick A disease
R Buccoliero, L Ginzburg, AH Futerman |
Journal of Inherited Metabolic Disease | 2004 |
|
Inhibitory effects of surfactant protein A on surfactant phospholipid hydrolysis by secreted phospholipases A2
S Chabot, K Koumanov, G Lambeau, MH Gelb, V Balloy, M Chignard, JA Whitsett, L Touqui |
Journal of immunology (Baltimore, Md. : 1950) | 2003 |
|
Surfactant protein�A and B genetic variants predispose to idiopathic pulmonary fibrosis
M Selman, HM Lin, M Montao, AL Jenkins, A Estrada, Z Lin, G Wang, SL DiAngelo, X Guo, TM Umstead, CM Lang, A Pardo, DS Phelps, J Floros |
Human Genetics | 2003 |
|
Transforming growth factor-β: A mediator of cell regulation in acute respiratory distress syndrome
JF Dhainaut, J Charpentier, JD Chiche |
Critical Care Medicine | 2003 |
|
THEROLE OFEXOGENOUSSURFACTANT IN THETREATMENT OFACUTELUNGINJURY
JF Lewis, R Veldhuizen |
Annual Review of Physiology | 2003 |
|
Prognostic value of surfactant proteins A and D in patients with acute lung injury*
IW Cheng, LB Ware, KE Greene, TJ Nuckton, MD Eisner, MA Matthay |
Critical Care Medicine | 2003 |
|
Changes in biochemical and biophysical surfactant properties with cardiopulmonary bypass in children
B Friedrich, R Schmidt, I Reiss, A Günther, W Seeger, M Müller, J Thul, D Schranz, L Gortner |
Critical Care Medicine | 2003 |
|
Aerosolized surfactant and dextran for experimental acute respiratory distress syndrome caused by acidified milk in rats
XG Cui, K Tashiro, H Matsumoto, Y Tsubokawa, T Kobayashi |
Acta Anaesthesiologica Scandinavica | 2003 |
|
The use of surfactant in children with acute respiratory distress syndrome: efficacy in terms of oxygenation, ventilation and mortality
H Yapıcıoğlu, D Yıldızdaş, İ Bayram, Y Sertdemir, HL Yılmaz |
Pulmonary Pharmacology & Therapeutics | 2003 |
|
Surfactant biology and clinical application
SE Poynter, AM LeVine |
Critical Care Clinics | 2003 |
|
Lung Biology in Health and Disease
N Zamel |
Lung Biology in Health and Disease: Experimental Models and Therapeutic Potential | 2003 |
|
Chemokines in the Lung
W Tsai, B Mehrad |
Chemokines in the Lung | 2003 |
|
Effect of Corticosteroid on Lung Parenchyma Remodeling at an Early Phase of Acute Lung Injury
PR Rocco, AB Souza, DS Faffe, CP Pássaro, FB Santos, EM Negri, JG Lima, RS Contador, VL Capelozzi, WA Zin |
American journal of respiratory and critical care medicine | 2003 |
|
Treatment of Acute Respiratory Distress Syndrome with Recombinant Surfactant Protein C Surfactant
RG Spragg, JF Lewis, W Wurst, D Häfner, RP Baughman, MD Wewers, JJ Marsh |
American journal of respiratory and critical care medicine | 2003 |
|
Surfactant Protein B Inhibits Endotoxin-Induced Lung Inflammation
R Epaud, M Ikegami, JA Whitsett, AH Jobe, TE Weaver, HT Akinbi |
American journal of respiratory cell and molecular biology | 2003 |
|
Bronchoalveolar Lavage Fluid Surfactant Protein-A and Surfactant Protein-D Are Inversely Related to Inflammation in Early Cystic Fibrosis
TL Noah, PC Murphy, JJ Alink, MW Leigh, WM Hull, MT Stahlman, JA Whitsett |
American journal of respiratory and critical care medicine | 2003 |
|
SP-B deficiency causes respiratory failure in adult mice
KR Melton, LL Nesslein, M Ikegami, JW Tichelaar, JC Clark, JA Whitsett, TE Weaver |
American journal of physiology. Lung cellular and molecular physiology | 2003 |
|
Surfactant strengthens the inhibitory effect of C-reactive protein on human lung macrophage cytokine release
C Casals, J Arias-Díaz, F Valiño, A Sáenz, C García, JL Balibrea, E Vara |
American journal of physiology. Lung cellular and molecular physiology | 2003 |
|
Early surfactant administration protects against lung dysfunction in a mouse model of ARDS
VP Rasaiah, JL Malloy, JF Lewis, RA Veldhuizen |
American journal of physiology. Lung cellular and molecular physiology | 2003 |
|
Nitric oxide inhibits surfactant protein B gene expression in lung epithelial cells
D Salinas, L Sparkman, K Berhane, V Boggaram |
American journal of physiology. Lung cellular and molecular physiology | 2003 |
|
Surfactant protein B: unambiguously necessary for adult pulmonary function
FS Cole |
American journal of physiology. Lung cellular and molecular physiology | 2003 |
|
Alterations in bronchoalveolar lavage fluid during ischemia-induced acute hepatic failure in the pig
G Kostopanagiotou |
Hepatology | 2003 |
|
Die Intensivtherapie bei akutem Lungenversagen
R Kuhlen, R Rossaint |
2003 | |
|
Monitoring alveolar epithelial function in acute lung injury
R H Hastings |
Journal of Clinical Monitoring and Computing | 2003 |
|
Regulation of surfactant proteins by LPS and proinflammatory cytokines in fetal and newborn lung
O Väyrynen, V Glumoff, M Hallman |
American journal of physiology. Lung cellular and molecular physiology | 2002 |
|
Clinical acute lung injury and acute respiratory distress syndrome
MA Matthay, T Uchida, X Fang |
Current Treatment Options in Cardiovascular Medicine | 2002 |
|
In vitro and in vivo intrapulmonary distribution of fluorescently labeled surfactant
RV Diemel, M Walch, HP Haagsman, G Putz |
Critical Care Medicine | 2002 |
|
Inhaled diazeniumdiolates (NONOates) as selective pulmonary vasodilators
PV van Heerden, S Sviri, KF Ilett, CF Lam |
Expert Opinion on Investigational Drugs | 2002 |
|
Surfactant Deficiency in Adults
RD Hite |
Clinical Pulmonary Medicine | 2002 |
|
The pulmonary epithelium is an important mediator of ventilator-induced lung injury*
MA Matthay |
Critical Care Medicine | 2002 |
|
Inhibition of human surfactant protein A function by oxidation intermediates of nitrite
IC Davis, S Zhu, JB Sampson, JP Crow, S Matalon |
Free radical biology & medicine | 2002 |
|
Clinical developments for treating ARDS
G Martin, S Eaton |
Expert Opinion on Investigational Drugs | 2002 |
|
Hydrophobic Surfactant Proteins in Lung Function and Disease
JA Whitsett, TE Weaver |
New England Journal of Medicine | 2002 |
|
Pharmacology of Acute Lung Injury
S Tasaka, N Hasegawa, A Ishizaka |
Pulmonary Pharmacology & Therapeutics | 2002 |
|
Acute respiratory distress syndrome epidemiology and pathophysiology
RJ Morrison, A Bidani |
Chest Surgery Clinics of North America | 2002 |
|
Chemical coupling of a monoclonal antisurfactant protein-B antibody to human urokinase for targeting surfactant-incorporating alveolar fibrin
C Ruppert, R Schmidt, F Grimminger, Y Suzuki, W Seeger, CM Lehr, A Günther |
Bioconjugate Chemistry | 2002 |
|
An ELISA technique for quantification of surfactant apoprotein (SP)-C in bronchoalveolar lavage fluid
R Schmidt, W Steinhilber, C Ruppert, C Daum, F Grimminger, W Seeger, A Günther |
American journal of respiratory and critical care medicine | 2002 |
|
Effect Of CTP:Phosphocholine Cytidylyltransferase Overexpression on the Mouse Lung Surfactant System
J Li, JJ Marsh, RG Spragg |
American journal of respiratory cell and molecular biology | 2002 |
|
Acute Lung Injury
GD Leikauf, SA McDowell, SC Wesselkamper, WD Hardie, JE Leikauf, TR Korfhagen, DR Prows |
Chest | 2002 |
|
Sharing signals: connecting lung epithelial cells with gap junction channels
M Koval |
American journal of physiology. Lung cellular and molecular physiology | 2002 |
|
The late asthmatic response is linked with increased surface tension and reduced surfactant protein B in mice
A Haczku, EN Atochina, Y Tomer, Y Cao, C Campbell, ST Scanlon, SJ Russo, G Enhorning, MF Beers |
American journal of physiology. Lung cellular and molecular physiology | 2002 |
|
Selected Contribution: Lung hypoxia: antioxidant and antiapoptotic effects of liposomal α-tocopherol
T Minko, A Stefanov, V Pozharov |
Journal of applied physiology | 2002 |
|
Altered fatty acid composition of lung surfactant phospholipids in interstitial lung disease
R Schmidt, U Meier, P Markart, F Grimminger, HG Velcovsky, H Morr, W Seeger, A Günther |
American journal of physiology. Lung cellular and molecular physiology | 2002 |
|
Effect of surface tension on alveolar surface area
JP Butler, RE Brown, D Stamenović, JP Morris, GP Topulos |
Journal of applied physiology | 2002 |
|
Surfactant Therapy in Infants and Children: Three Years Experience in a Pediatric Intensive Care Unit:
MM Hermon, J Golej, G Burda, H Boigner, E Stoll, K Vergesslich, W Strohmaier, A Pollak, G Trittenwein |
Shock | 2002 |
|
Infant animal model of pulmonary mycotoxicosis induced by Stachybotrys chartarum
Iwona Yike, Martha J Miller, W G Sorenson, Ronald Walenga, Joseph F Tomashefski Jr, Dorr G Dearborn |
Mycopathologia | 2002 |
|
Ischemic pre-conditioning of 5 minutes but not of 10 minutes improves lung function after warm ischemia in a canine model
I Friedrich, J Spillner, EX Lu, B Bartling, M Barnscheid, A Sablotzki, U Schade, JC Reidemeister, RE Silber, A Gunther, J Borgermann |
The Journal of Heart and Lung Transplantation | 2001 |
|
Surfactant and corticosteroid effects on lung function in a rat model of acute lung injury
CM Chen, CL Fang, CH Chang |
Critical Care Medicine | 2001 |
|
Therapeutic time-window of a group IIA phospholipase A2 inhibitor in rabbit acute lung injury: Correlation with lung surfactant protection
S Furue, K Mikawa, K Nishina, M Shiga, M Ueno, Y Tomita, K Kuwabara, I Teshirogi, T Ono, Y Hori, A Matsukawa, M Yoshinaga, H Obara |
Critical Care Medicine | 2001 |
|
Calfactant
D Willson |
Expert Opinion on Pharmacotherapy | 2001 |
|
Surfactant alteration and replacement in acute respiratory distress syndrome
A Günther, C Ruppert, R Schmidt, P Markart, F Grimminger, D Walmrath, W Seeger |
Respiratory Research | 2001 |
|
Surfactant proteins: role in lung physiology and disease in early life
G.B.Mallory |
Paediatric Respiratory Reviews | 2001 |
|
Surfactant in respiratory distress syndrome and lung injury
M Hallman, V Glumoff, M Rämet |
Comparative Biochemistry and Physiology - Part A Molecular & Integrative Physiology | 2001 |
|
Treatment and Prevention of Acute Respiratory Failure
GF de Anda, B Lachmann |
Archives of Medical Research | 2001 |
|
Surfactant proteins a and d and pulmonary host defense
JC Clark, SE Wert, CJ Bachurski, MT Stahlman, BR Stripp, TE Weaver, JA Whitsett |
Annual Review of Physiology | 2001 |
|
Functional Tests for the Characterization of Surfactant Protein B (SP-B) and a Fluorescent SP-B Analog
RV Diemel, D Bader, M Walch, B Hotter, LM van Golde, A Amann, HP Haagsman, G Putz |
Archives of Biochemistry and Biophysics | 2001 |
|
Respiratory support of critically ill children
S Nakagawa, D Bohn |
Clinical Intensive Care | 2001 |
|
Surfactant proteins a and d and pulmonary host defense
JC Clark, SE Wert, CJ Bachurski, MT Stahlman, BR Stripp, TE Weaver, JA Whitsett |
Annual Review of Physiology | 2001 |
|
Decreased Surfactant Protein-B Expression and Surfactant Dysfunction in a Murine Model of Acute Lung Injury
EP Ingenito, R Mora, M Cullivan, Y Marzan, K Haley, L Mark, LA Sonna |
American journal of respiratory cell and molecular biology | 2001 |
|
Alteration of Fatty Acid Profiles in Different Pulmonary Surfactant Phospholipids in Acute Respiratory Distress Syndrome and Severe Pneumonia
R Schmidt, U Meier, M Yabut-Perez, D Walmrath, F Grimminger, W Seeger, A Günther |
American journal of respiratory and critical care medicine | 2001 |
|
Lung Tissue Mechanics and Extracellular Matrix Remodeling in Acute Lung Injury
PR Rocco, EM Negri, PM Kurtz, FP Vasconcellos, GH Silva, VL Capelozzi, PV Romero, WA Zin |
American journal of respiratory and critical care medicine | 2001 |
|
Elevated Plasma Surfactant Protein-B Predicts Development of Acute Respiratory Distress Syndrome in Patients with Acute Respiratory Failure
AD Bersten, T Hunt, TE Nicholas, IR Doyle |
American journal of respiratory and critical care medicine | 2001 |
|
Acute lung injury: cellular mechanisms and derangements
MA Schwarz |
Paediatric Respiratory Reviews | 2001 |
|
Immunohistochemistry of pulmonary surfactant-associated protein A in acute respiratory distress syndrome
BL Zhu, K Ishida, L Quan, MQ Fujita, H Maeda |
Legal Medicine | 2001 |
|
Evaluation of Exogenous Surfactant in HCl-induced Lung Injury
AM Brackenbury, PS Puligandla, LY McCAIG, V Nikore, LJ Yao, RA Veldhuizen, JF Lewis |
American journal of respiratory and critical care medicine | 2001 |
|
LUNG SALVAGE AND PROTECTION VENTILATORY TECHNIQUES
D Bohn |
Pediatric Clinics of North America | 2001 |
|
Functional Mapping of Surfactant Protein A
FX McCormack |
Pediatric Pathology & Molecular Medicine | 2001 |
|
Interaction of bacterial lipopolysaccharide with mouse surfactant protein C inserted into lipid vesicles
L Augusto, KL Blay, G Auger, D Blanot, R Chaby |
American journal of physiology. Lung cellular and molecular physiology | 2001 |
|
Mechanical ventilation of isolated septic rat lungs: effects on surfactant and inflammatory cytokines
T Nakamura, J Malloy, L McCaig, LJ Yao, M Joseph, J Lewis, R Veldhuizen |
Journal of applied physiology | 2001 |
|
Molecular Biology of Acute Lung Injury
HR Wong, TP Shanley |
2001 | |
|
Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E
A Gullo |
2001 | |
|
Gene Therapy for Acute and Acquired Diseases
P Factor |
2001 | |
|
Postnatal development and control of the pulmonary surfactant system in the tammar wallaby Macropus eugenii
NJ Miller, S Orgeig, CB Daniels, RV Baudinette |
The Journal of experimental biology | 2001 |
|
Thirty years of clinical trials in acute respiratory distress syndrome
RC McIntyre, EJ Pulido, DD Bensard, BD Shames, E Abraham |
Critical Care Medicine | 2000 |
|
Phospholipase A secreted byLegionella pneumophiladestroys alveolar surfactant phospholipids
A Flieger, S Gong, M Faigle, HA Mayer, U Kehrer, J MuÃotter, P Bartmann, B Neumeister |
FEMS Microbiology Letters | 2000 |
|
Biphasic Regulation of Fc-Receptor Mediated Phagocytosis of Rabbit Alveolar Macrophages by Surfactant Phospholipids
T Morito, K Oishi, M Yamamoto, K Matsumoto |
The Tohoku Journal of Experimental Medicine | 2000 |
|
Mitochondrial Glutathione Replacement Restores Surfactant Synthesis and Secretion in Alveolar Epithelial Cells of Ethanol-Fed Rats
DM Guidot, AS Brown |
Alcoholism, clinical and experimental research | 2000 |
|
Polymorphisms of human SP-A, SP-B, and SP-D genes: association of SP-B Thr131Ile with ARDS
Z Lin, C Pearson, V Chinchilli, SM Pietschmann, J Luo, U Pison, J Floros |
Clinical Genetics | 2000 |
|
Composition of alveolar surfactant changes with training in humans
IR Doyle, S Morton, AJ Crockett, HA Barr, KG Davidson, MJ Jones, ME Jones, TE Nicholas |
Respirology | 2000 |
|
Pulmonary surfactant is altered during mechanical ventilation of isolated rat lung
RA Veldhuizen, LN Tremblay, A Govindarajan, BA van Rozendaal, HP Haagsman, AS Slutsky |
Critical Care Medicine | 2000 |
|
Pathophysiology and Implications for Treatment of Acute Respiratory Distress Syndrome
MH van Soeren, WL Diehl-Jones, RJ Maykut, WM Haddara |
AACN Clinical Issues: Advanced Practice in Acute & Critical Care | 2000 |
|
Very low surfactant protein C contents in newborn Belgian White and Blue calves with respiratory distress syndrome
F Danlois, S Zaltash, J Johansson, B Robertson, HP Haagsman, M Eijk, MF Beers, F Rollin, JM Ruysschaert, G Vandenbussche |
Biochemical Journal | 2000 |
|
ACUTE RESPIRATORY DISTRESS SYNDROME
BD Conner, GR Bernard |
Clinics in Chest Medicine | 2000 |
|
SURFACTANT REPLACEMENT THERAPY
RG Spragg |
Clinics in Chest Medicine | 2000 |
|
Soluble Nitric Oxide Donor and Surfactant Improve Oxygenation and Pulmonary Hypertension in Porcine Lung Injury
BR Jacobs, DJ Smith, B Zingarelli, DJ Passerini, ET Ballard, RJ Brilli |
Nitric Oxide | 2000 |
|
Immunohistochemistry of pulmonary surfactant apoprotein A in forensic autopsy: reassessment in relation to the causes of death
BL Zhu, K Ishida, L Quan, MQ Fujita, H Maeda |
Forensic Science International | 2000 |
|
Surfactant Modulates Intracellular Signaling of the Adhesion Receptor L-Selectin
B Brenner, S Junge, A Birle, S Kadel, O Linderkamp |
Pediatric Research | 2000 |
|
Unified nomenclature for the winged helix/forkhead transcription factors
LB Ware, MA Matthay |
Genes & development | 2000 |
|
Recognition of Bacterial Endotoxin in the Lungs
TR Martin |
American journal of respiratory cell and molecular biology | 2000 |
|
Differential Impact of Ultrasonically Nebulized Versus Tracheal-instilled Surfactant on Ventilation-Perfusion (V˙ A /Q˙) Mismatch in a Model of Acute Lung Injury
RT Schermuly, A Günther, N Weissmann, HA Ghofrani, W Seeger, F Grimminger, D Walmrath |
American journal of respiratory and critical care medicine | 2000 |
|
Degree of Lung Maturity Determines the Direction of the Interleukin-1– Induced Effect on the Expression of Surfactant Proteins
V Glumoff, O Väyrynen, T Kangas, M Hallman |
American journal of respiratory cell and molecular biology | 2000 |
|
Differential Gene Expression in the Initiation and Progression of Nickel-Induced Acute Lung Injury
SA McDowell, K Gammon, CJ Bachurski, JS Wiest, JE Leikauf, DR Prows, GD Leikauf |
American journal of respiratory cell and molecular biology | 2000 |
|
Pivotal Role of Anionic Phospholipids in Determining Dynamic Behavior of Lung Surfactant
EP Ingenito, R Mora, L Mark |
American journal of respiratory and critical care medicine | 2000 |
|
Commercial versus Native Surfactants: Surface Activity, Molecular Components, and the Effect of Calcium
W Bernhard, J Mottaghian, A Gebert, GA Rau, HO von der HARDT, CF Poets |
American journal of respiratory and critical care medicine | 2000 |
|
Surfactant—A review for pediatric surgeons
AJ McCabe, DT Wilcox, BA Holm, PL Glick |
Journal of Pediatric Surgery | 2000 |
|
Mitochondrial Glutathione Replacement Restores Surfactant Synthesis and Secretion in Alveolar Epithelial Cells of Ethanol-Fed Rats:
DM Guidot, LA Brown |
Alcoholism, clinical and experimental research | 2000 |
|
At surfactant deficiency, application of "the open lung concept" prevents protein leakage and attenuates changes in lung mechanics:
A Hartog, GF de Anda, D Gommers, U Kaisers, B Lachmann |
Critical Care Medicine | 2000 |
|
Function and Composition of Pulmonary Surfactant and Surfactant-Derived Fatty Acid Profiles Are Altered in Young Adults With Cystic Fibrosis
KC Meyer, A Sharma, R Brown, M Weatherly, FR Moya, J Lewandoski, JJ Zimmerman |
Chest | 2000 |
|
Effects of ventilation on the surfactant system in sepsis-induced lung injury
JL Malloy, RA Veldhuizen, JF Lewis |
Journal of applied physiology | 2000 |
|
Effects of intratracheal instillation of TNF-α on surfactant metabolism
RG Salome, DM McCoy, AJ Ryan, RK Mallampalli |
Journal of applied physiology | 2000 |
|
Determinants of surfactant function in acute lung injury and early recovery
R Mora, S Arold, Y Marzan, B Suki, EP Ingenito |
American journal of physiology. Lung cellular and molecular physiology | 2000 |
|
Effect of recombinant SP-C surfactant in a porcine lavage model of acute lung injury
RG Spragg, RM Smith, K Harris, J Lewis, D Häfner, P Germann |
Journal of applied physiology | 2000 |
|
Characterization of rabbit SP-B promoter region responsive to downregulation by tumor necrosis factor-α
K Berhane, RK Margana, V Boggaram |
American journal of physiology. Lung cellular and molecular physiology | 2000 |
|
Alveolar environment influences the metabolic and biophysical properties of exogenous surfactants
PS Puligandla, T Gill, LA McCaig, LJ Yao, RA Veldhuizen, F Possmayer, JF Lewis |
Journal of applied physiology | 2000 |
|
P. carinii induces selective alterations in component expression and biophysical activity of lung surfactant
EN Atochina, MF Beers, ST Scanlon, AM Preston, JM Beck |
American journal of physiology. Lung cellular and molecular physiology | 2000 |
|
Surfactant components modulate fibroblast apoptosis and type I collagen and collagenase-1 expression
LV de Lara, C Becerril, M Montaño, C Ramos, V Maldonado, J Meléndez, DS Phelps, A Pardo, M Selman |
American journal of physiology. Lung cellular and molecular physiology | 2000 |
|
Adenoviral E3-14.7K protein in LPS-induced lung inflammation
KS Harrod, AD Mounday, JA Whitsett |
American journal of physiology. Lung cellular and molecular physiology | 2000 |
|
Alveolar type II cell abnormalities and peroxide formation in lungs of rats given IL-1 intratracheally
B M Hybertson, Y M Lee, H G Cho, O J Cho, J E Repine |
Inflammation | 2000 |
|
Ethanol Ingestion Impairs Alveolar Epithelial Glutathione Homeostasis and Function, and Predisposes to Endotoxin-Mediated Acute Lung Injury
D Guidot, M Moss, F Holguin, M Lois, L Brown |
Journal of Clinical Investigation | 1999 |
|
Instillation of calf lung surfactant extract (calfactant) is beneficial in pediatric acute hypoxemic respiratory failure
DF Willson, A Zaritsky, LA Bauman, K Dockery, RL James, D Conrad, H Craft, WE Novotny, EA Egan, H Dalton |
Critical Care Medicine | 1999 |
|
Keratinocyte Growth Factor Protects Alveolar Epithelium and Endothelium from Oxygen-Induced Injury in Mice
C Barazzone, YR Donati, AF Rochat, C Vesin, CD Kan, JC Pache, PF Piguet |
The American Journal of Pathology | 1999 |
|
Hydrophobic lung surfactant proteins B and C remain associated with surface film during dynamic cyclic area changes
G Putz, M Walch, M Vaneijk, H Haagsman |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 1999 |
|
Pneumocystis carinii pneumonia in HIV-infected patients: effect of steroid therapy on surfactant level
J Dichter, J Lundgren, T Nielsen, B Jensen, J Schattenkerk, T Benfield, M Lawrence, J Shelhamer |
Respiratory Medicine | 1999 |
|
Surfactant treatment for acute respiratory distress syndrome
J López-Herce, N Lucas, A Carrillo, A Bustinza, R Moral |
Archives of disease in childhood | 1999 |
|
Endogenous Surfactant Metabolism in Critically Ill Infants Measured with Stable Isotope Labeled Fatty Acids
PE Cogo, VP Carnielli, JE Bunt, T Badon, G Giordano, F Zacchello, PJ Sauer, LJ Zimmermann |
Pediatric Research | 1999 |
|
Multiple Mechanisms of Lung Surfactant Inhibition
BA Holm, Z Wang, RH Notter |
Pediatric Research | 1999 |
|
A role for phospholipase A2 in ARDS pathogenesis
L Touqui, L Arbibe |
Molecular Medicine Today | 1999 |
|
Inhibition of lung surfactant protein B expression during Pneumocystis carinii pneumonia in mice
MF Beers, EN Atochina, AM Preston, JM Beck |
Journal of Laboratory and Clinical Medicine | 1999 |
|
Normal surfactant pool sizes and inhibition-resistant surfactant from mice that overexpress surfactant protein A
BM Elhalwagi, M Zhang, M Ikegami, HS Iwamoto, RE Morris, ML Miller, K Dienger, FX McCormack |
American journal of respiratory cell and molecular biology | 1999 |
|
Damage to surfactant-specific protein in acute respiratory distress syndrome
HJ Hoppe, KB Reid |
Lancet | 1999 |
|
Bronchiolitis: A Four-Year Comparative Evaluation of the Impact of a Clinical Care Pathway on Patient Outcome and Resource Utilization Using a Large National Dataset
J Todd, D Bertoch, S Dolan |
Pediatric Research | 1999 |
|
Lung Epithelium–specific Proteins: Characteristics and Potential Applications as Markers
C Hermans, A Bernard |
American journal of respiratory and critical care medicine | 1999 |
|
Serial Changes in Surfactant-associated Proteins in Lung and Serum before and after Onset of ARDS
KE Greene, JR Wright, KP Steinberg, JT Ruzinski, E Caldwell, WB Wong, W Hull, JA Whitsett, T Akino, Y Kuroki, H Nagae, LD Hudson, TR Martin |
American journal of respiratory and critical care medicine | 1999 |
|
Cleavage of Surfactant-Incorporating Fibrin by Different Fibrinolytic Agents: Kinetics of Lysis and Rescue of Surface Activity
A Günther, P Markart, M Kalinowski, C Ruppert, F Grimminger, W Seeger |
American journal of respiratory cell and molecular biology | 1999 |
|
Surfactant Protein B Deficiency Worsens Hyperoxic Injury to the Alveolar Epithelium
J Hickman-Davis, S Matalon |
American journal of respiratory cell and molecular biology | 1999 |
|
Prostacyclin Enhances Stretch-induced Surfactant Secretion in Alveolar Epithelial Type II Cells
F Rose, K Zwick, HA Ghofrani, U Sibelius, W Seeger, D Walmrath, F Grimminger |
American journal of respiratory and critical care medicine | 1999 |
|
Surfactant Protein Levels in Severe Respiratory Syncytial Virus Infection
MH Kerr, JY Paton |
American journal of respiratory and critical care medicine | 1999 |
|
Local effect of lung contusion on lung surfactant composition in multiple trauma patients:
M Aufmkolk, R Fischer, G Voggenreiter, C Kleinschmidt, KP Schmit-Neuerburg, U Obertacke |
Critical Care Medicine | 1999 |
|
Oxidant-mediated lung injury in the acute respiratory distress syndrome:
MA Matthay, T Geiser, S Matalon, H Ischiropoulos |
Critical Care Medicine | 1999 |
|
Lung Cytokines and ARDS
TR Martin |
Chest | 1999 |
|
Compositional, structural, and functional alterations in pulmonary surfactant in surgical patients after the early onset of systemic inflammatory response syndrome or sepsis:
K Raymondos, M Leuwer, PL Haslam, B Vangerow, M Ensink, H Tschorn, W Schurmann, H Husstedt, H Rueckoldt, S Piepenbrock |
Critical Care Medicine | 1999 |
|
SP-A enhances viral clearance and inhibits inflammation after pulmonary adenoviral infection
KS Harrod, BC Trapnell, K Otake, TR Korfhagen, JA Whitsett |
American journal of physiology. Lung cellular and molecular physiology | 1999 |
|
The effect of perfluoroisobutene and phosgene on rat lavage fluid surfactant phospholipids
B Jugg, J Jenner, P Rice |
Human & Experimental Toxicology | 1999 |
|
Regulation of mouse SP-B gene promoter by AP-1 family members
Z Sever-Chroneos, CJ Bachurski, C Yan, JA Whitsett |
American journal of physiology. Lung cellular and molecular physiology | 1999 |
|
Chemokines in Disease
CA Hébert |
1999 | |
|
Temporal Sequence of Pulmonary and Systemic Inflammatory Responses to Graded Polymicrobial Peritonitis in Mice
RN Moore, C Stamme, DS Bundschuh, T Hartung, U Gebert, L Wollin, R Nüsing, A Wendel, S Uhlig |
Infection and immunity | 1999 |
|
Adjunctive Drug Treatment in Severe Hypoxic Respiratory Failure:
S Elsasser, H Schchinger, W Strobel |
Drugs | 1999 |
|
Generation of lyso-phospholipids from surfactant in acute lung injury is mediated by type-II phospholipase A2 and inhibited by a direct surfactant protein A-phospholipase A2 protein interaction
L Arbibe, K Koumanov, D Vial, C Rougeot, G Faure, N Havet, S Longacre, BB Vargaftig, G Béréziat, DR Voelker, C Wolf, L Touqui |
Journal of Clinical Investigation | 1998 |
|
Surfactant protein-A : New insights into an old protein-II
AR Kumar, JM Snyder |
The Indian Journal of Pediatrics | 1998 |
|
The association of type II pneumocytes and endothelial permeability with the pulmonary custocyte system in experimental acute pancreatitis
Wang, Borjesson, Sun, Wallen, Deng, Zhang, Hallberg, Andersson |
European Journal of Clinical Investigation | 1998 |
|
Bronchoalveolar lavage fluid characteristics of early intermediate and late phases of ARDS
G Nakos, EI Kitsiouli, I Tsangaris, ME Lekka |
Intensive Care Medicine | 1998 |
|
RESPIRATORY MECHANICS AND SURFACTANT IN THE ACUTE RESPIRATORY DISTRESS SYNDROME
AD Bersten, K Davidson, TE Nicholas, IR Doyle |
Clinical and Experimental Pharmacology and Physiology | 1998 |
|
SURFACTANT PROTEINS: Molecular Genetics of Neonatal Pulmonary Diseases
J Floros, P Kala |
Annual Review of Physiology | 1998 |
|
Regulation and Function of Pulmonary Surfactant Protein B
GS Pryhuber |
Molecular Genetics and Metabolism | 1998 |
|
Nitric oxide decreases surfactant protein A gene expression in H441 cells
O Ayad, HR Wong |
Critical Care Medicine | 1998 |
|
Studies in Interface Science
R Herold, R Dewitz, S Schürch, U Pison |
Studies in Interface Science | 1998 |
|
Oxidative damage of the pulmonary surfactant system
HP Haagsman |
Seminars in Neonatology | 1998 |
|
Transient surfactant protein B deficiency in a term infant with severe respiratory failure
JM Klein, MW Thompson, JM Snyder, TN George, JA Whitsett, EF Bell, PB McCray, LM Nogee |
The Journal of Pediatrics | 1998 |
|
The American–European Consensus Conference on ARDS, Part 2: Ventilatory, Pharmacologic, Supportive Therapy, Study Design Strategies, and Issues Related to Recovery and Remodeling
A Artigas, GR Bernard, J Carlet, D Dreyfuss, L Gattinoni, L Hudson, M Lamy, JJ Marini, MA Matthay, MR Pinsky, R Spragg, PM Suter |
American journal of respiratory and critical care medicine | 1998 |
|
Artificial Surfactant (Surfactant TA) Modulates Adherence and Superoxide Production of Neutrophils
A Suwabe, K Otake, N Yakuwa, H Suzuki, M Ito, H Tomoike, Y Saito, K Takahashi |
American journal of respiratory and critical care medicine | 1998 |
|
Additivity of Protein and Nonprotein Inhibitors of Lung Surfactant Activity
Z Wang, RH Notter |
American journal of respiratory and critical care medicine | 1998 |
|
Lavage Administration of Dilute Surfactants after Acute Lung Injury in Neonatal Piglets
V Balaraman, J Meister, TL Ku, SL Sood, E Tam, J Killeen, CF Uyehara, E Egan, D Easa |
American journal of respiratory and critical care medicine | 1998 |
|
Hepatocyte Growth Factor and Keratinocyte Growth Factor in the Pulmonary Edema Fluid of Patients with Acute Lung Injury: Biologic and Clinical Significance
GM Verghese, K McCORMICK-SHANNON, RJ Mason, MA Matthay |
American journal of respiratory and critical care medicine | 1998 |
|
Pulmonary Surfactant Activity Is Impaired in Lung Transplant Recipients
JM Hohlfeld, E Tiryaki, H Hamm, HG Hoymann, N Krug, A Haverich, H Fabel |
American journal of respiratory and critical care medicine | 1998 |
|
Early Alterations in Intracellular and Alveolar Surfactant of the Rat Lung in Response to Endotoxin
H Fehrenbach, F Brasch, S Uhlig, M Weisser, C Stamme, A Wendel, J Richter |
American journal of respiratory and critical care medicine | 1998 |
|
Effects of Ventilation Strategies on the Efficacy of Exogenous Surfactant Therapy in a Rabbit Model of Acute Lung Injury
Y Ito, SE Manwell, CL Kerr, RA Veldhuizen, LJ Yao, D Bjarneson, LY McCAIG, AJ Bartlett, JF Lewis |
American journal of respiratory and critical care medicine | 1998 |
|
Intensive care support of the patient with pneumonia: Current approaches to mechanical ventilation and other adjuvant therapies
AE Thompson |
Seminars in Pediatric Infectious Diseases | 1998 |
|
Aerosolized Surfactant Improves Pulmonary Function in Endotoxin-induced Lung Injury
C Lutz, D Carney, C Finck, A Picone, LA Gatto, A Paskanik, E Langenback, G Nieman |
American journal of respiratory and critical care medicine | 1998 |
|
A subject of ongoing investigation: Can exogenous surfactant be used to treat ARDS?
D Serna, M Brenner, JC Chen |
Critical Care Medicine | 1998 |
|
Exogenous surfactant and positive end-expiratory pressure in the treatment of endotoxin-induced lung injury:
CJ Lutz, A Picone, LA Gatto, A Paskanik, S Landas, GF Nieman |
Critical Care Medicine | 1998 |
|
Acute Respiratory Distress Syndrome: Potential Pharmacologic Interventions
B Kaufman, P Dhar |
Journal of Pharmacy Practice | 1998 |
|
Regulation of surfactant proteins A and B by TNF-α and phorbol ester independent of NF-κB
GS Pryhuber, R Khalak, Q Zhao |
American journal of physiology. Lung cellular and molecular physiology | 1998 |
|
Surfactant protein A and surfactant protein D in health and disease
RJ Mason, K Greene, DR Voelker |
American journal of physiology. Lung cellular and molecular physiology | 1998 |
|
TGF-β1 inhibits surfactant component expression and epithelial cell maturation in cultured human fetal lung
MF Beers, KO Solarin, SH Guttentag, J Rosenbloom, A Kormilli, LW Gonzales, PL Ballard |
American journal of physiology. Lung cellular and molecular physiology | 1998 |
|
Hydrolysis of surfactant-associated phosphatidylcholine by mammalian secretory phospholipases A 2
RD Hite, MC Seeds, RB Jacinto, R Balasubramanian, M Waite, D Bass |
American journal of physiology. Lung cellular and molecular physiology | 1998 |
|
Anaesthesia, Pain, Intensive Care and Emergency Medicine - A.P.I.C.E
A Gullo |
1998 | |
|
Applied Physiology in Respiratory Mechanics
J Milic-Emili |
1998 | |
|
Liquid Ventilation
RC Leonard |
ANAESTH INTENS CARE | 1998 |
|
The American-European consensus conference on ARDS, Part 2: Ventilatory, pharmacologic, supportive therapy, study design strategies and issues related to recovery and remodeling
A Artigas, GR Bernard, J Carlet, D Dreyfuss, L Gattinoni, L Hudson, M Lamy, JJ Marini, MA Matthay, MR Pinsky, R Spragg, PM Suter |
Intensive Care Medicine | 1998 |
|
Bronchoalveolar lavage fluid characteristics of early intermediate and late phases of ARDS: Alterations in leukocytes, proteins, PAF and surfactant components
G Nakos, EI Kitsiouli, I Tsangaris, ME Lekka |
Intensive Care Medicine | 1998 |
|
PULMONARY SURFACTANT: PHYSICAL CHEMISTRY, PHYSIOLOGY, AND REPLACEMENT
RH Notter, Z Wang |
Reviews in Chemical Engineering | 1997 |
|
Surfactant replacement therapy in ARDS: white knight or noise in the system?
TE Nicholas, IR Doyle, AD Bersten |
Thorax | 1997 |
|
Effect of genotype on the levels of surfactant protein A mRNA and on the SP-A2 splice variants in adult humans
AM Karinch, DE deMello, J Floros |
Biochemical Journal | 1997 |
|
Transcriptional regulation of surfactant proteins SP-A and SP-B by phorbol ester
BC Planer, Y Ning, SA Kumar, PL Ballard |
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression | 1997 |
|
Lung transplantation for treatment of infants with surfactant protein B deficiency
A Hamvas, LM Nogee, GB Mallory, TL Spray, CB Huddleston, A August, LP Dehner, DE deMello, M Moxley, R Nelson, FS Cole, HR Colten |
The Journal of Pediatrics | 1997 |
|
Surfactant protein B deficiency: Insights into inherited disorders of lung cell metabolism
A Hamvas |
Current Problems in Pediatrics | 1997 |
|
Primary Importance of Zwitterionic Over Anionic Phospholipids in the Surface-active Function of Calf Lung Surfactant Extract
Z Wang, O Gurel, S Weinbach, RH Notter |
American journal of respiratory and critical care medicine | 1997 |
|
Surfactant Proteins-A and -B Are Elevated in Plasma of Patients with Acute Respiratory Failure
IR Doyle, AD Bersten, TE Nicholas |
American journal of respiratory and critical care medicine | 1997 |
|
Ultrasonic Nebulization for Efficient Delivery of Surfactant in a Model of Acute Lung Injury: Impact on Gas Exchange
R Schermuly, T Schmehl, A Günther, F Grimminger, W Seeger, D Walmrath |
American journal of respiratory and critical care medicine | 1997 |
|
Intratracheal Aerosolization of Endotoxin (LPS) in the Rat: A Comprehensive Animal Model to Study Adult (Acute) Respiratory Distress Syndrome
HP van Helden, WC Kuijpers, D Steenvoorden, C Go, PL Bruijnzeel, M Eijk, HP Haagsman |
Experimental Lung Research | 1997 |
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Mechanisms of Surfactant Dysfunction in Early Acute Lung Injury
M Kennedy, D Phelps, E Ingenito |
Experimental Lung Research | 1997 |
|
Hyaluronan Production in vitro by Fetal Lung Fibroblasts and Epithelial Cells Exposed to Surfactants of N-acetylcysteine
H Johnsson, P Heldin, G Sedin, TC Laurent |
Upsala Journal of Medical Sciences | 1997 |
|
Exosurf enhances adenovirus-mediated gene transfer to alveolar type II cells
SM Manuel, Y Guo, S Matalon |
American journal of physiology. Lung cellular and molecular physiology | 1997 |
|
Pulmonary dysfunction in neonatal SP-B-deficient mice
K Tokieda, JA Whitsett, JC Clark, TE Weaver, K Ikeda, KB McConnell, AH Jobe, M Ikegami, HS Iwamoto |
American journal of physiology. Lung cellular and molecular physiology | 1997 |
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Effect of Thyroid Hormone (T sub 3)-responsive Changes in Surfactant Apoproteins on Surfactant Function During Sepsis:
AM Raafat, AP Franko, R Zafar, SA Dulchavsky, LN Diebel, S Ksenzenko |
The Journal of Trauma: Injury, Infection and Critical Care | 1997 |
|
Applied Cardiovascular Physiology
MR Pinsky |
1997 | |
|
Effect of N-nitroso-N-methylurethane on gas exchange, lung compliance, and surfactant function of rabbits
D Pappert, N Gilliard, G Heldt, TA Merritt, PD Wagner, RG Spragg |
Intensive Care Medicine | 1996 |
|
Surfactant: a review of its functions and relevance in adult respiratory disorders
H Hamm, C Kroegel, J Hohlfeld |
Respiratory Medicine | 1996 |
|
Effects of human polymorphonuclear leukocyte elastase upon surfactant proteins in vitro
D Liau |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1996 |
|
The pulmonary surfactant system: biological functions, components, physicochemical properties and alterations during lung disease
U Pison |
Colloids and Surfaces A: Physicochemical and Engineering Aspects | 1996 |
|
Lung preservation: The importance of endothelial and alveolar type II cell integrity
RJ Novick, KE Gehman, IS Ali, J Lee |
The Annals of Thoracic Surgery | 1996 |
|
Consensus on Surfactant and Inhaled Nitric Oxide for ARDS
JE Gadek |
Journal of Aerosol Medicine | 1996 |
|
Clinical diagnostic criteria of the adult respiratory distress syndrome in the intensive care unit
DS Zaccardelli, EN Pattishall |
Critical Care Medicine | 1996 |
|
Surfactant treatment in experimental Escherichia coli pneumonia
GW Song, B Robertson, T Curstedt, XZ Gan, WX Huang |
Acta Anaesthesiologica Scandinavica | 1996 |
|
Effects of Prenatal Treatment with Betamethasone,L-Carnitine, or Betamethasone-L-Carnitine Combinations on the Phosphatidylcholine Content and Composition of the Foetal and Maternal Rat Lung
A Lohninger, HP Krieglsteiner, F Hajos, H Stangl, R Marz |
Clinical Chemistry and Laboratory Medicine | 1996 |
|
Surfactant: Current and Potential Therapeutic Application in Infants and Adults
J Lewis, RA Veldhuizen |
Journal of Aerosol Medicine | 1996 |
|
ADJUNCTS TO MECHANICAL VENTILATION
A Nahum, R Shapiro |
Clinics in Chest Medicine | 1996 |
|
The Acute Respiratory Distress Syndrome
MA Matthay |
New England Journal of Medicine | 1996 |
|
Aerosolized Surfactant in Adults with Sepsis-Induced Acute Respiratory Distress Syndrome
A Anzueto, RP Baughman, KK Guntupalli, JG Weg, HP Wiedemann, AA Raventós, F Lemaire, W Long, DS Zaccardelli, EN Pattishall |
New England Journal of Medicine | 1996 |
|
Functional impairment of bronchoalveolar lavage phospholipids in early Pneumocystis carinii pneumonia in rats
TH Su, V Natarajan, DL Kachel, MA Moxley, WJ Longmore, WJ Martin |
Journal of Laboratory and Clinical Medicine | 1996 |
|
A profile of amino acid and catecholamine levels during endotoxin-induced acute lung injury in sheep: Searching for potential markers of the acute respiratory distress syndrome
JM Hofford, L Milakofsky, S Pell, W Vogel |
Journal of Laboratory and Clinical Medicine | 1996 |
|
Surfactant and acquired lung diseases
HP Wiedemann |
Journal of Laboratory and Clinical Medicine | 1996 |
|
Surfactant content in children with inflammatory lung disease:
AM LeVine, A Lotze, S Stanley, C Stroud, R O'Donnell, J Whitsett, MM Pollack |
Critical Care Medicine | 1996 |
|
Clara Cell Protein (CC-16) and Surfactant-Associated Protein A (SP-A) in Asbestos-Exposed Workers
O Lesur, AM Bernard, RO Bégin |
Chest | 1996 |
|
Aerosolized and instilled surfactant therapies for acute lung injury caused by intratracheal endotoxin in rats:
K Tashiro, K Yamada, WZ Li, Y Matsumoto, T Kobayashi |
Critical Care Medicine | 1996 |
|
Susceptibility of exogenous surfactant to phospholipase Α 2 degradation
JE Duncan, GM Hatch, J Belik |
Canadian Journal of Physiology and Pharmacology | 1996 |
|
Effect of Lung Contusion on Surfactant Composition in Multiple-Trauma Patients:
M Aufmkolk, R Fischer, C Kleinschmidt, U Obertacke, KP Schmit-Neuerburg |
The Journal of Trauma: Injury, Infection and Critical Care | 1996 |
|
Oxygen Transport to Tissue XVII
C Ince, J Kesecioglu, L Telci, K Akpir |
1996 | |
|
ARDS Acute Respiratory Distress in Adults
TW Evans, C Haslett |
1996 | |
|
59. Jahrestagung der Deutschen Gesellschaft für Unfallchirurgie e.V
G Muhr, KE Rehm |
1996 | |
|
Inhibitory effect of porcine surfactant on the respiratory burst oxidase in human neutrophils. Attenuation of p47phox and p67phox membrane translocation as the mechanism
W Chao, RG Spragg, RM Smith |
Journal of Clinical Investigation | 1995 |
|
In VitroandIn VivoTransfer and Expression of Human Surfactant SP-A- and SP-B-Associated Protein cDNAs Mediated by Replication-Deficient, Recombinant Adenoviral Vectors
RJ Korst, B Bewig, RG Crystal |
Human Gene Therapy | 1995 |
|
Surfactant replacement therapy for non-respiratory distress syndrome neonatal respiratory disease —research or clinical application?
A Greenough |
European Journal of Pediatrics | 1995 |
|
Frequency and importance of barotrauma in 100 patients with acute lung injury
LM Schnapp, DP Chin, N Szaflarski, MA Matthay |
Critical Care Medicine | 1995 |
|
Measurement of lung volumes and pulmonary mechanics during weaning of newborn infants with intractable respiratory failure from extracorporeal membrane oxygenation
A Kugelman, K Saiki, AC Platzker, M Garg |
Pediatric Pulmonology | 1995 |
|
Morphometric characterisation of the fine structure of human type II pneumocytes
H Fehrenbach, A Schmiedl, T Wahlers, SW Hirt, F Brasch, D Riemann, J Richter |
The Anatomical Record | 1995 |
|
Surfactant replacement therapy--room for improvement
RJ Mason |
The Western journal of medicine | 1995 |
|
Translation in vivo of 5' untranslated-region splice variants of human surfactant protein-A
AM Karinch, J Floros |
Biochemical Journal | 1995 |
|
Dose-response comparisons of five lung surfactant factor (LSF) preparations in an animal model of adult respiratory distress syndrome (ARDS)
D Häfner, R Beume, U Kilian, G Krasznai, B Lachmann |
British Journal of Pharmacology | 1995 |
|
In Vivo Studies of Aerosolized Exogenous Surfactant
JF Lewis |
Aerosol Science and Technology | 1995 |
|
New concepts in the treatment of children with acute respiratory distress syndrome
TE Paulson, RM Spear, BM Peterson |
The Journal of Pediatrics | 1995 |
|
Recent advances in the treatment of ARDS
R Rossaint, D Pappert, G Fritz |
Clinical Intensive Care | 1995 |
|
New Therapies for ARDS
LD Hudson |
Chest | 1995 |
|
Tumor Necrosis Factor-α Inhibits Surfactant Protein C Gene Transcription
CJ Bachurski, GS Pryhuber, SW Glasser, SE Kelly, JA Whitsett |
The Journal of biological chemistry | 1995 |
|
58. Jahrestagung der Deutschen Gesellschaft für Unfallchirurgie e.V
A Rüter, KE Rehm |
1995 | |
|
Pulmonary surfactant: unanswered questions
NJ Gross |
Thorax | 1995 |
|
Prevention and therapy of the adult respiratory distress syndrome
B Temmesfeld-Wollbrück, D Walmrath, F Grimminger, W Seeger |
Lung | 1995 |
|
Respiratorische Therapie nach operativen Eingriffen
E Rügheimer |
1995 | |
|
Exposure of the hydrophobic components of porcine lung surfactant to oxidant stress alters surface tension properties
N Gilliard, GP Heldt, J Loredo, H Gasser, H Redl, TA Merritt, RG Spragg |
Journal of Clinical Investigation | 1994 |
|
Tumor necrosis factor-alpha-induced inhibition of phosphatidylcholine synthesis by human type II pneumocytes is partially mediated by prostaglandins
J Arias-Díaz, E Vara, C García, JL Balibrea |
Journal of Clinical Investigation | 1994 |
|
In vivo evaluation of the inhibitory capacity of human plasma on exogenous surfactant function
B Lachmann, EP Eijking, KL So, D Gommers |
Intensive Care Medicine | 1994 |
|
Host defence capacities of pulmonary surfactant: evidence for ‘non-surfactant’ functions of the surfactant system
U Pison, M Max, A Neuendank, S WEIßBACH, S Pietschmann |
European Journal of Clinical Investigation | 1994 |
|
Fatty acid composition of lung, macrophage and surfactant phospholipids after short-term enteral feeding with n−3 lipids
JD Palombo, EE Lydon, PL Chen, BR Bistrian, RA Forse |
Lipids | 1994 |
|
Surface-area cycling of different surfactant preparations: SP-A and SP-B are essential for large-aggregate integrity
RA Veldhuizen, SA Hearn, JF Lewis, F Possmayer |
Biochemical Journal | 1994 |
|
Role of alveolar type II cells and of surfactant-associated protein C mRNA levels in the pathogenesis of respiratory distress in mink kits infected with Aleutian mink disease parvovirus
B Viuff, B Aasted, S Alexandersen |
Journal of virology | 1994 |
|
Binding of human collectins (SP-A and MBP) to influenza virus
R Malhotra, JS Haurum, S Thiel, RB Sim |
Biochemical Journal | 1994 |
|
Advances and issues in bronchopulmonary dysplasia
JJ Zimmerman, PM Farrell |
Current Problems in Pediatrics | 1994 |
|
Surfactant protein B deficiency: Antenatal diagnosis and prospective treatment with surfactant replacement
A Hamvas, FS Cole, DE deMello, M Moxley, JA Whitsett, HR Colten, LM Nogee |
The Journal of Pediatrics | 1994 |
|
Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis
G Dranoff, AD Crawford, M Sadelain, B Ream, A Rashid, RT Bronson, GR Dickersin, CJ Bachurski, EL Mark, JA Whitsett |
Science | 1994 |
|
Bronchoalveolar lavage studies of pulmonary surfactant
PL Haslam |
Archivos de Bronconeumología | 1994 |
|
Acute Effects of a Single Dose of Porcine Surfactant on Patients With the Adult Respiratory Distress Syndrome
RG Spragg, N Gilliard, P Richman, RM Smith, RD Hite, D Pappert, B Robertson, T Curstedt, D Strayer |
Chest | 1994 |
|
Novel Therapies for acute Respiratory Failure
JC Ring, GL Stidham |
Pediatric Clinics of North America | 1994 |
|
Role of the Coagulation System in ARDS
N Hasegawa, AW Husari, WT Hart, TG Kandra, TA Raffin |
Chest | 1994 |
|
Yearbook of Intensive Care and Emergency Medicine 1994
JL Vincent |
1994 | |
|
Metabolismus
G Kleinberger, K Lenz, R Ritz, B Schneeweiß, HP Schuster, W Waldhäusl |
1994 | |
|
Exogenous surfactant therapy in thirty-eight hour lung graft preservation for transplantation
RJ Novick, RA Veldhuizen, F Possmayer, J Lee, D Sandler, JF Lewis |
The Journal of Thoracic and Cardiovascular Surgery | 1994 |
|
Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large tumor antigen transgenic mice
KA Wikenheiser, DK Vorbroker, WR Rice, JC Clark, CJ Bachurski, HK Oie, JA Whitsett |
Proceedings of the National Academy of Sciences | 1993 |
|
Exosurf treatment following wood smoke inhalation
D Feldbaum, D Wormuth, G Nieman, M Paskanik, W Clark, T Hakim |
Burns | 1993 |
|
Improved pulmonary outcome after exogenous surfactant therapy for respiratory failure in term infants requiring extracorporeal membrane oxygenation
A Lotze, GR Knight, GR Martin, DI Bulas, WM Hull, RM O'Donnell, JA Whitsett, BL Short |
The Journal of Pediatrics | 1993 |
|
Surfactant and the Adult Respiratory Distress Syndrome
JF Lewis, AH Jobe |
American journal of respiratory and critical care medicine | 1993 |
|
Alterations in Pulmonary Surfactant Composition and Activity after Experimental Lung Transplantation
RA Veldhuizen, J Lee, D Sandler, W Hull, JA Whitsett, J Lewis, F Possmayer, RJ Novick |
American journal of respiratory and critical care medicine | 1993 |
|
Physiologic Responses and Distribution of Aerosolized Surfactant (Survanta®) in a Nonuniform Pattern of Lung Injury
JF Lewis, MH Ikegami, AH Jobe, D Absolom |
American journal of respiratory and critical care medicine | 1993 |
|
Decreased Surfactant Protein A in Patients with Bacterial Pneumonia
RP Baughman, RI Sternberg, W Hull, JA Buchsbaum, J Whitsett |
American journal of respiratory and critical care medicine | 1993 |
|
Other Uses of Surfactant
DL Brown, EN Pattishall |
Clinics in Perinatology | 1993 |
|
Pathophysiology of Shock, Sepsis, and Organ Failure
G Schlag, H Redl |
1993 | |
|
Alveolar surfactant and adult respiratory distress syndrome: Pathogenetic role and therapeutic prospects
W Seeger, A Gnther, HD Walmrath, F Grimminger, HG Lasch |
The Clinical Investigator | 1993 |
|
Acute ozone-induced lung injury in rats: Structural-functional relationships of developing alveolar edema
JF Paterson, MD Hammond, MR Montgomery, JT Sharp, SE Farrier, JU Balis |
Toxicology and Applied Pharmacology | 1992 |
|
Utilisation des surfactants exogènes dans le traitement du syndrome de détresse respiratoire de l'adulte
H Walti |
Réanimation Urgences | 1992 |
|
Reduction of Pulmonary Surfactant in Patients with Human Immunodeficiency Virus Infection and Pneumocystis carinii Pneumonia
AG Hoffman, MG Lawrence, FP Ognibene, AF Suffredini, GY Lipschik, JA Kovacs, H Masur, JH Shelhamer |
Chest | 1992 |
|
Therapie innerer Krankheiten
G Riecker |
1991 |
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