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Citations to this article

1,25-dihydroxyvitamin D3 prevents the in vivo induction of murine experimental autoimmune encephalomyelitis.
J M Lemire, D C Archer
J M Lemire, D C Archer
Published March 1, 1991
Citation Information: J Clin Invest. 1991;87(3):1103-1107. https://doi.org/10.1172/JCI115072.
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1,25-dihydroxyvitamin D3 prevents the in vivo induction of murine experimental autoimmune encephalomyelitis.

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Abstract

The hormone, 1,25-dihydroxyvitamin D3 (1,25-[OH]2-D3), inhibits lymphocyte activation in vitro. We studied the ability of the vitamin D metabolite to interfere in vivo with a primary T cell-mediated model of autoimmunity, murine experimental autoimmune encephalomyelitis (EAE). Within 2 wk of antigenic challenge, immunized animals will develop acute paralysis with central nervous tissue inflammation. If mice survive, a rise in antibody titer develops within a month. The administration of 0.1 microgram 1,25-(OH)2-D3 i.p. given every other day for 15 d, starting 3 d before immunization, significantly prevented the development of EAE. The rise in antibody titer to myelin basic protein was also abrogated. Histopathologic lesions of EAE were inhibited by treatment with the sterol. These results suggest a potent immunosuppressive role for 1,25-(OH)2-D3 in vivo in the modulation of a cell-mediated model of autoimmunity.

Authors

J M Lemire, D C Archer

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P Millet, V Landel, I Virard, M Morello, F Féron
Cahiers de Nutrition et de Diététique 2014
Role of vitamin D3 in Treatment of Lumbar Disc Herniation—Pain and Sensory Aspects: Study Protocol for a Randomized Controlled Trial
M Sedighi, A Haghnegahdar
Trials 2014
Vitamin D and Crohn’s Disease in the Adult Patient: A Review
A Basson
JPEN. Journal of parenteral and enteral nutrition 2014
Higher weight in adolescence and young adulthood is associated with an earlier age at multiple sclerosis onset
KS Kavak, BE Teter, J Hagemeier, K Zakalik, B Weinstock-Guttman, K Edwards, A Goodman, M Gottesman, J Herbert, I Kister, B Jubelt, P Coyle, L Krupp, M Lenihan, A Gerber, A Perel, R Zivadinov, C Granger
Multiple sclerosis (Houndmills, Basingstoke, England) 2014
1,25-Dihydroxyvitamin D3 selectively and reversibly impairs T helper-cell CNS localization
IV Grishkan, AN Fairchild, PA Calabresi, AR Gocke
Proceedings of the National Academy of Sciences 2013
The neuropathology of obesity: insights from human disease
EB Lee, MP Mattson
Acta Neuropathologica 2013
Vitamin D Biology Revealed Through the Study of Knockout and Transgenic Mouse Models
S Christakos, T Seth, J Hirsch, A Porta, A Moulas, P Dhawan
Annual Review of Nutrition 2013
Can we prevent or treat multiple sclerosis by individualised vitamin D supply?
J Dörr, A Döring, F Paul
The EPMA Journal 2013
Serum levels of 25-hydroxy vitamin D in normal Biozzi and C57BL/6 mice and during the course of chronic relapsing experimental autoimmune encephalomyelitis (CR EAE)
C Bolton, J Gates, G Giovannoni
Inflammation Research 2013
Suppression of experimental autoimmune encephalomyelitis by 300–315nm ultraviolet light
Y Wang, SJ Marling, SM McKnight, AL Danielson, KS Severson, HF Deluca
Archives of Biochemistry and Biophysics 2013
Dietary vitamin D deficiency in rats from middle to old age leads to elevated tyrosine nitration and proteomics changes in levels of key proteins in brain: Implications for low vitamin D-dependent age-related cognitive decline
JT Keeney, S Förster, R Sultana, LD Brewer, CS Latimer, J Cai, JB Klein, NM Porter, DA Butterfield
Free radical biology & medicine 2013
Sex-specific environmental influences affecting MS development
J Correale, ME Aguirre, MF Farez
Clinical Immunology 2013
Textbook of Natural Medicine
JA Bralley, RS Lord
Textbook of Natural Medicine 2013
The influence of vitamin D supplementation on melatonin status in patients with multiple sclerosis
D Golan, E Staun-Ram, L Glass-Marmor, I Lavi, O Rozenberg, S Dishon, M Barak, S Ish-Shalom, A Miller
Brain, Behavior, and Immunity 2013
Review: The role of vitamin D in nervous system health and disease: Vitamin D and the brain
GC DeLuca, SM Kimball, J Kolasinski, SV Ramagopalan, GC Ebers
Neuropathology and Applied Neurobiology 2013
Efficacy of vitamin D in treating multiple sclerosis-like neuroinflammation depends on developmental stage
MZ Adzemovic, M Zeitelhofer, S Hochmeister, SA Gustafsson, M Jagodic
Experimental Neurology 2013
Effects of Vitamin D3, Calcipotriol and FTY720 on the Expression of Surface Molecules and Cytolytic Activities of Human Natural Killer Cells and Dendritic Cells
Z Al-Jaderi, A Maghazachi
Toxins 2013
Intradermal application of vitamin D3 increases migration of CD14+ dermal dendritic cells and promotes the development of Foxp3+ regulatory T cells
G Bakdash, LP Schneider, TM van Capel, ML Kapsenberg, MB Teunissen, EC de Jong
Human Vaccines & Immunotherapeutics 2013
Intradermal application of vitamin D3 increases migration of CD14 (+) dermal dendritic cells and promotes the development of Foxp3 (+) regulatory T cells
G Bakdash, LP Schneider, TM van Capel, ML Kapsenberg, MB Teunissen, EC de Jong
Human Vaccines & Immunotherapeutics 2013
Environmental factors acting during development to influence MS risk: insights from animal studies
DN Krementsov, C Teuscher
Multiple sclerosis (Houndmills, Basingstoke, England) 2013
Environmental factors and their regulation of immunity in multiple sclerosis
MW Koch, LM Metz, SM Agrawal, VW Yong
Journal of the Neurological Sciences 2013
The Ifng Gene Is Essential for Vdr Gene Expression and Vitamin D 3 -Mediated Reduction of the Pathogenic T Cell Burden in the Central Nervous System in Experimental Autoimmune Encephalomyelitis, a Multiple Sclerosis Model
JA Spanier, FE Nashold, JK Olson, CE Hayes
Journal of immunology (Baltimore, Md. : 1950) 2012
Efficacy of Vitamin D Supplementation in Multiple Sclerosis (EVIDIMS Trial): study protocol for a randomized controlled trial
J Dörr, S Ohlraun, H Skarabis, F Paul
Trials 2012
Pathogenesis of multiple sclerosis via environmental and genetic dysregulation of N-glycosylation
A Grigorian, H Mkhikian, CF Li, BL Newton, RW Zhou, M Demetriou
Seminars in Immunopathology 2012
Vitamin D deficiency affects the immunity against Mycobacterium tuberculosis infection in mice
H Yang, Z Zhang, Z Chang, K Tang, D Lin, J Xu
Clinical and Experimental Medicine 2012
Multiple Sclerosis: New Insights in Pathogenesis and Novel Therapeutics
D Ontaneda, M Hyland, JA Cohen
Annual Review of Medicine 2012
Development of experimental autoimmune encephalomyelitis (EAE) in mice requires vitamin D and the vitamin D receptor
Y Wang, SJ Marling, JG Zhu, KS Severson, HF DeLuca
Proceedings of the National Academy of Sciences 2012
Epidemiology and Genetics
PL de Jager
Multiple Sclerosis Diagnosis and Therapy 2012
Extraskeletal Effects of Vitamin D
H Wolden-Kirk, C Gysemans, A Verstuyf, C Mathieu
Endocrinology and metabolism clinics of North America 2012
Effects of ultraviolet light on human serum 25-hydroxyvitamin D and systemic immune function
SV Milliken, H Wassall, BJ Lewis, J Logie, RN Barker, H Macdonald, MA Vickers, AD Ormerod
Journal of Allergy and Clinical Immunology 2012
Vitamin D und Multiple Sklerose: Der Stellenwert für das Erkrankungsrisiko und die Behandlung
A Döring, F Paul, J Dörr
Der Nervenarzt 2012
The nervous system's potential role in multiple sclerosis associated bone loss
S Josyula, BK Mehta, Y Karmon, B Teter, S Batista, J Ostroff, B Weinstock-Guttman
Journal of the Neurological Sciences 2012
Hazai konszenzus a D-vitamin szerepéről a betegségek megelőzésében és kezelésében
I Takács, I Benkő, E Toldy, N Wikonkál, L Szekeres, E Bodolay, E Kiss, Z Jambrik, B Szabó, B Merkely, Z Valkusz, T Kovács, A Szabó, O Grigoreff, Z Nagy, J Demeter, HC Horváth, N Bittner, S Várbíró, P Lakatos
Orvosi Hetilap 2012
Fat-soluble vitamins as disease modulators in multiple sclerosis
Ø Torkildsen, KI Løken-Amsrud, S Wergeland, KM Myhr, T Holmøy
Acta Neurologica Scandinavica 2012
Role of Vitamin D in the Onset, Progression and Severity of Multiple Sclerosis
S Mesliniene, L Ramrattan, S Giddings, M Sheikh-Ali
Endocrine Practice 2012
Oxidative Stress and Disease: Oxidative Stress, Immunity, and Aging
P Singh, M Campbell
Oxidative Stress and Disease 2012
Cerebrospinal fluid proteome comparison between multiple sclerosis patients and controls
AC Kroksveen, A Guldbrandsen, C Vedeler, KM Myhr, JA Opsahl, FS Berven
Acta Neurologica Scandinavica 2012
1,25-Dihyroxyvitamin D3 promotes FOXP3 expression via binding to vitamin D response elements in its conserved noncoding sequence region
SW Kang, SH Kim, N Lee, WW Lee, KA Hwang, MS Shin, SH Lee, WU Kim, I Kang
Journal of immunology (Baltimore, Md. : 1950) 2012
Contribution of vitamin D insufficiency to the pathogenesis of multiple sclerosis
C Pierrot-Deseilligny, JC Souberbielle
Therapeutic advances in neurological disorders 2012
Vitamin D Responsive Elements within the HLA-DRB1 Promoter Region in Sardinian Multiple Sclerosis Associated Alleles
E Cocco, A Meloni, MR Murru, D Corongiu, S Tranquilli, E Fadda, R Murru, L Schirru, MA Secci, G Costa, I Asunis, S Cuccu, G Fenu, L Lorefice, N Carboni, G Mura, MC Rosatelli, MG Marrosu, M Campbell
PloS one 2012
1,25-Dihyroxyvitamin D 3 Promotes FOXP3 Expression via Binding to Vitamin D Response Elements in Its Conserved Noncoding Sequence Region
SW Kang, SH Kim, N Lee, WW Lee, KA Hwang, MS Shin, SH Lee, WU Kim, I Kang
Journal of immunology (Baltimore, Md. : 1950) 2012
The beneficial role of vitamin D in systemic lupus erythematosus (SLE)
K vinh quốc Lương, LT Nguyễn
Clinical Rheumatology 2012
Vitamin D, Multiple Sclerosis and Inflammatory Bowel Disease
MT Cantorna
Archives of Biochemistry and Biophysics 2011
Impact of Vitamin D in the Treatment of Tuberculosis
K Luong, LT Nguyen
The American Journal of the Medical Sciences 2011
Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis
H Mkhikian, A Grigorian, CF Li, HL Chen, B Newton, RW Zhou, C Beeton, S Torossian, GG Tatarian, SU Lee, K Lau, E Walker, KA Siminovitch, KG Chandy, Z Yu, JW Dennis, M Demetriou
Nature Communications 2011
Predominance of Th2 polarization by vitamin D through a STAT6-dependent mechanism
S Sloka, C Silva, J Wang, VW Yong
Journal of Neuroinflammation 2011
Vitamin D receptor (VDR) gene SNPs influence VDR expression and modulate protection from multiple sclerosis in HLA-DRB1*15-positive individuals
C Agliardi, FR Guerini, M Saresella, D Caputo, MA Leone, M Zanzottera, E Bolognesi, I Marventano, N Barizzone, ME Fasano, N Al-Daghri, M Clerici
Brain, Behavior, and Immunity 2011
Assessment of evidence for a protective role of vitamin D in multiple sclerosis
HE Hanwell, B Banwell
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2011
Vitamin D in the healthy and inflamed central nervous system
J Smolders, SM Moen, J Damoiseaux, I Huitinga, T Holmøy
Journal of the Neurological Sciences 2011
Therapeutic Effect of Vitamin D3 in Multiple Sclerosis Patients
G Mosayebi, A Ghazavi, K Ghasami, Y Jand, P Kokhaei
Immunological Investigations 2011
Individual and Joint Action of Environmental Factors and Risk of MS
IA der Mei, S Simpson, J Stankovich, BV Taylor
Neurologic Clinics 2011
Environmental Factors in Multiple Sclerosis: Epstein-Barr Virus, Vitamin D, and Cigarette Smoking
DM Wingerchuk
Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine 2011
Vitamin D deficiency diminishes the severity and delays onset of experimental autoimmune encephalomyelitis
HF DeLuca, LA Plum
Archives of Biochemistry and Biophysics 2011
Efficacy and mechanisms of action of vitamin D in experimental polyarthritis
M Moghaddami, G Mayrhofer, PH Anderson, HA Morris, MV der Hoek, LG Cleland
Immunology and Cell Biology 2011
Vitamin D and multiple sclerosis: can vitamin D prevent disease progression?
B Mehta, M Ramanathan, B Weinstock-Guttman
Expert Review of Neurotherapeutics 2011
Vitamin D-mediated immune regulation in Multiple Sclerosis
J Correale, MC Ysrraelit, MI Gaitán
Journal of the Neurological Sciences 2011
Sun Exposure, Vitamin D Intake and Progression to Disability among Veterans with Progressive Multiple Sclerosis
TY McDowell, S Amr, WJ Culpepper, P Langenberg, W Royal, C Bever, DD Bradham
Neuroepidemiology 2011
Seasonal, gestational and postnatal influences on multiple sclerosis: The beneficial role of a vitamin D supplementation during early life
DA de Abreu, V Landel, F Féron
Journal of the Neurological Sciences 2011
Does Vitamin D Affect Risk of Developing Autoimmune Disease?: A Systematic Review
MA Kriegel, JA Manson, KH Costenbader
Seminars in Arthritis and Rheumatism 2011
Minireview: Vitamin D: Is There a Role in Extraskeletal Health?
S Christakos, HF DeLuca
Endocrinology 2011
Polymorphisms in the vitamin D receptor gene and multiple sclerosis risk: A meta-analysis of case–control studies
J Huang, ZF Xie
Journal of the Neurological Sciences 2011
Vitamine D et auto-immunité. Deuxième partie : aspects cliniques
Y Schoindre, B Terrier, JE Kahn, D Saadoun, JC Souberbielle, O Benveniste, Z Amoura, JC Piette, P Cacoub, N Costedoat-Chalumeau
La Revue de Médecine Interne 2011
Vitamin D and the immune system: Getting it right
C Mathieu
IBMS BoneKEy 2011
Vitamin D and Multiple Sclerosis
CE Hayes, FE Nashold, CG Mayne, JA Spanier, CD Nelson
Vitamin D 2011
Control of Adaptive Immunity by Vitamin D Receptor Agonists
L Adorini
Vitamin D 2011
XVI European Charcot Foundation lecture: nutrition and environment: can MS be prevented?
KC Simon, KL Munger, A Ascherio
Journal of the Neurological Sciences 2011
Vitamin D and multiple sclerosis: Potential pathophysiological role and clinical implications
SJ Dudani, S Kalhan, SP Sharma
International journal of applied & basic medical research 2011
Regulation of Mycobacterium-Specific Mononuclear Cell Responses by 25-Hydroxyvitamin D3
CD Nelson, BJ Nonnecke, TA Reinhardt, WR Waters, DC Beitz, JD Lippolis, JH Fritz
PloS one 2011
1,25-Dihydroxyvitamin D3 Ameliorates Th17 Autoimmunity via Transcriptional Modulation of Interleukin-17A
S Joshi, LC Pantalena, XK Liu, SL Gaffen, H Liu, C Rohowsky-Kochan, K Ichiyama, A Yoshimura, L Steinman, S Christakos, S Youssef
Molecular and cellular biology 2011
Clinical Neuroimmunology
SA Rizvi, PK Coyle
2011
Therapeutic approaches to multiple sclerosis: an update on failed, interrupted, or inconclusive trials of neuroprotective and alternative treatment strategies
SG Meuth, S Bittner, JC Ulzheimer, C Kleinschnitz, BC Kieseier, H Wiendl
BioDrugs 2010
Therapeutic approaches to multiple sclerosis: an update on failed, interrupted, or inconclusive trials of neuroprotective and alternative treatment strategies
SG Meuth, S Bittner, JC Ulzheimer, C Kleinschnitz, BC Kieseier, H Wiendl
BioDrugs 2010
The essential role of Epstein-Barr virus in the pathogenesis of multiple sclerosis
MP Pender
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 2010
Lineage-specific Effects of 1,25-Dihydroxyvitamin D3 on the Development of Effector CD4 T Cells*
MT Palmer, YK Lee, CL Maynard, JR Oliver, DD Bikle, AM Jetten, CT Weaver
The Journal of biological chemistry 2010
Vitamin D, disease and therapeutic opportunities
LA Plum, HF DeLuca
Nature Reviews Drug Discovery 2010
Vitamin D and multiple sclerosis
A Ascherio, KL Munger, KC Simon
The Lancet Neurology 2010
The expanding spectrum of biological actions of vitamin D
J Rojas-Rivera, CD la Piedra, A Ramos, A Ortiz, J Egido
Nephrology Dialysis Transplantation 2010
Is hypovitaminosis D one of the environmental risk factors for multiple sclerosis?
C Pierrot-Deseilligny, JC Souberbielle
Brain 2010
Fall prevention and vitamin D in the elderly: an overview of the key role of the non-bone effects
C Annweiler, M Montero-Odasso, AM Schott, G Berrut, B Fantino, O Beauchet
Journal of neuroengineering and rehabilitation 2010
Complementary and alternative medicine for the treatment of multiple sclerosis
V Yadav, L Shinto, D Bourdette
Expert Review of Clinical Immunology 2010
UV radiation suppresses experimental autoimmune encephalomyelitis independent of vitamin D production
BR Becklund, KS Severson, SV Vang, HF DeLuca
Proceedings of the National Academy of Sciences 2010
The impact of vitamin D on dendritic cell function in patients with systemic lupus erythematosus
I Ben-Zvi, C Aranow, M Mackay, A Stanevsky, DL Kamen, LM Marinescu, CE Collins, GS Gilkeson, B Diamond, JA Hardin
PloS one 2010
Role of vitamin D in immune responses and autoimmune diseases, with emphasis on its role in multiple sclerosis
HL Zhang, J Wu
Neuroscience Bulletin 2010
Multiple Sclerosis and Vitamin D: A Review and Recommendations
AJ Solomon, RH Whitham
Current Neurology and Neuroscience Reports 2010
Very low levels of vitamin D in systemic sclerosis patients
P Caramaschi, AD Gassa, O Ruzzenente, A Volpe, V Ravagnani, I Tinazzi, G Barausse, LM Bambara, D Biasi
Clinical Rheumatology 2010
1α,25-Dihydroxyvitamin D3 and all-trans retinoic acid synergistically inhibit the differentiation and expansion of Th17 cells
U Ikeda, D Wakita, T Ohkuri, K Chamoto, H Kitamura, Y Iwakura, T Nishimura
Immunology Letters 2010
The beneficial role of vitamin D and its analogs in cancer treatment and prevention
K Luong, LT Nguyen
Critical Reviews in Oncology/Hematology 2010
Vitamin D and multiple sclerosis: what are the guidelines for a reliable clinical trial?
F Féron
Expert Review of Neurotherapeutics 2010
Season of birth and multiple sclerosis in Sweden
J Salzer, A Svenningsson, P Sundström
Acta Neurologica Scandinavica 2010
New hypotheses on sunlight and the geographic variability of multiple sclerosis prevalence
BK Mehta
Journal of the Neurological Sciences 2010
Vitamins & Hormones
KJ Hare, FK Knop
Vitamins & Hormones 2010
The Effect of Vitamin D3 Alone and Mixed With IFN-γ on Tachyzoites of Toxoplasma gondii (RH Strain) Proliferation and Nitric Oxide (NO) Production in Infected Macrophages of BALB/C Mice
F Ghaffarifar, MA Pour, Z Sharifi, AD Asl, E Al-Kawaz
Iranian Journal of Parasitology 2010
Blue Books of Neurology
H Wiendl, N Melzer, C Kleinschnitz, SG Meuth
Blue Books of Neurology 2010
Vitamin D and Multiple Sclerosis:
E Stevens
Topics in clinical nutrition 2010
Les effets extra-osseux de la vitamine D : faits, questions et controverses
B Bouvard, C Annveiller, A Sallé, O Beauchet, D Chappard, M Audran, E Legrand
Revue du Rhumatisme 2010
Lineage-specific Effects of 1,25-Dihydroxyvitamin D 3 on the Development of Effector CD4 T Cells
MT Palmer, YK Lee, CL Maynard, JR Oliver, DD Bikle, AM Jetten, CT Weaver
The Journal of biological chemistry 2010
Regulation of calcium signaling in dendritic cells by 1,25-dihydroxyvitamin D 3
E Shumilina, NT Xuan, N Matzner, M Bhandaru, IM Zemtsova, F Lang
The FASEB Journal 2010
Gender Differences in 1,25 Dihydroxyvitamin D 3 Immunomodulatory Effects in Multiple Sclerosis Patients and Healthy Subjects
J Correale, MC Ysrraelit, MI Gaitán
Journal of immunology (Baltimore, Md. : 1950) 2010
Enhancement of 1,25-dihydroxyvitamin D3-mediated suppression of experimental autoimmune encephalomyelitis by calcitonin
BR Becklund, DW Hansen, HF Deluca
Proceedings of the National Academy of Sciences 2009
Combination treatment with progesterone and vitamin D hormone may be more effective than monotherapy for nervous system injury and disease
M Cekic, I Sayeed, DG Stein
Frontiers in Neuroendocrinology 2009
Epidemiology of Multiple Sclerosis: Environmental Factors
Ascherio A, Munger KL
Blue Books of Neurology 2009
Body size and risk of MS in two cohorts of US women
KL Munger, T Chitnis, A Ascherio
Neurology 2009
Impact on allergic immune response after treatment with vitamin A
V Matheu, K Berggård, Y Barrios, Y Barrios, MR Arnau, JM Zubeldia, ML Baeza, O Back, S Issazadeh-Navikas
Nutrition & Metabolism 2009
Clinical implications of a possible role of vitamin D in multiple sclerosis
C Pierrot-Deseilligny
Journal of Neurology 2009
Paricalcitol reduces basal and lipopolysaccharide-induced (LPS) TNF-α and IL-8 production by human peripheral blood mononuclear cells
T Eleftheriadis, G Antoniadi, V Liakopoulos, C Kartsios, I Stefanidis, G Galaktidou
International Urology and Nephrology 2009
Vitamin-regulated cytokines and growth factors in the CNS and elsewhere
G Scalabrino
Journal of Neurochemistry 2009
Long-term trends in the incidence of type 1 diabetes in Denmark: the seasonal variation changes over time
J Svensson, A Lyngaae-Jørgensen, B Carstensen, LB Simonsen, HB Mortensen
Pediatric Diabetes 2009
Multiple sclerosis: clinical features, pathophysiology, neuroimaging and future therapies
AP Borazanci, MK Harris, RN Schwendimann, E Gonzalez-Toledo, AH Maghzi, M Etemadifar, N Alekseeva, J Pinkston, RE Kelley, A Minagar
Future Neurology 2009
Immunomodulatory effects of Vitamin D in multiple sclerosis
J Correale, MC Ysrraelit, MI Gaitan
Brain 2009
Gender differences in multiple sclerosis: Cytokines and vitamin D
MJ Eikelenboom, J Killestein, JJ Kragt, BM Uitdehaag, CH Polman
Journal of the Neurological Sciences 2009
Vitamin D, a neuro-immunomodulator: Implications for neurodegenerative and autoimmune diseases
DA de Abreu, D Eyles, F Féron
Psychoneuroendocrinology 2009
A salmon based diet protects mice from behavioural changes in the cuprizone model for demyelination
Ø Torkildsen, LA Brunborg, AM Milde, SJ Mørk, KM Myhr, L Bø
Clinical Nutrition 2009
The calcitonin/calcitonin gene related peptide-α gene is not required for 1α,25-dihydroxyvitamin D3-mediated suppression of experimental autoimmune encephalomyelitis
BR Becklund, BJ James, RF Gagel, HF DeLuca
Archives of Biochemistry and Biophysics 2009
Higher levels of 25-hydroxyvitamin D are associated with a lower incidence of multiple sclerosis only in women
JJ Kragt, BM Amerongen, J Killestein, CD Dijkstra, BM Uitdehaag, CH Polman, P Lips
Multiple sclerosis (Houndmills, Basingstoke, England) 2009
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.
Nature Genetics 2009
Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice
R Bouillon, G Carmeliet, L Verlinden, E van Etten, A Verstuyf, HF Luderer, L Lieben, C Mathieu, M Demay
Endocrine reviews 2008
Vitamin effects on the immune system: vitamins A and D take centre stage
JR Mora, M Iwata, UH von Andrian
Nature Reviews Immunology 2008
Vitamin D deficiency modulates Graves' hyperthyroidism induced in BALB/c mice by thyrotropin receptor immunization
A Misharin, M Hewison, CR Chen, V Lagishetty, HA Aliesky, Y Mizutori, B Rapoport, SM McLachlan
Endocrinology 2008
The paradoxical effects of vitamin D on type 1 mediated immunity
MT Cantorna, S Yu, D Bruce
Molecular Aspects of Medicine 2008
Vitamin D in systemic lupus erythematosus
D Kamen, C Aranow
Current Opinion in Rheumatology 2008
Vitamin D analogs: Therapeutic applications and mechanisms for selectivity
AJ Brown, E Slatopolsky
Molecular Aspects of Medicine 2008
Novel therapeutic strategies for multiple sclerosis — a multifaceted adversary
RS Lopez-Diego, HL Weiner
Nature Reviews Drug Discovery 2008
Vitamin D and multiple sclerosis
A Raghuwanshi, SS Joshi, S Christakos
Journal of Cellular Biochemistry 2008
Vitamin D as an immune modulator in multiple sclerosis, a review
J Smolders, J Damoiseaux, P Menheere, R Hupperts
Journal of Neuroimmunology 2008
Vitamin D2Potentiates Axon Regeneration
JF Chabas, O Alluin, G Rao, S Garcia, MN Lavaut, JJ Risso, R Legre, G Magalon, M Khrestchatisky, T Marqueste, P Decherchi, F Feron
Journal of Neurotrauma 2008
Vitamin D and rheumatoid arthritis: is there a link?
G KIRAN, D DEBASHISH
International Journal of Rheumatic Diseases 2008
Examining the evidence: complementary adjunctive therapies for multiple sclerosis
M Namaka, A Crook, A Doupe, K Kler, M Vasconcelos, M Klowak, Y Gong, A Wojewnik-Smith, M Melanson
Neurological Research 2008
Principles of Bone Biology
CJ Rosen, T Niu
Principles of Bone Biology 2008
Vitamin D signaling in immune-mediated disorders: Evolving insights and therapeutic opportunities
F Baeke, E Etten, C Gysemans, L Overbergh, C Mathieu
Molecular Aspects of Medicine 2008
Association of vitamin D metabolite levels with relapse rate and disability in multiple sclerosis
J Smolders, P Menheere, A Kessels, J Damoiseaux, R Hupperts
Multiple sclerosis (Houndmills, Basingstoke, England) 2008
Vitamin D and autoimmunity: new aetiological and therapeutic considerations
Y Arnson, H Amital, Y Shoenfeld
Annals of the rheumatic diseases 2007
Vitamin D receptor signaling contributes to susceptibility to infection with Leishmania major
J Ehrchen, L Helming, G Varga, B Pasche, K Loser, M Gunzer, C Sunderkötter, C Sorg, J Roth, A Lengeling
The FASEB Journal 2007
Vitamin D Receptor Agonists in the Treatment of Autoimmune Diseases: Selective Targeting of Myeloid but Not Plasmacytoid Dendritic Cells
G Penna, S Amuchastegui, G Laverny, L Adorini
Journal of Bone and Mineral Research 2007
Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes
R Bailey, JD Cooper, L Zeitels, DJ Smyth, JH Yang, NM Walker, E Hyppönen, DB Dunger, E Ramos-Lopez, K Badenhoop, S Nejentsev, JA Todd
Diabetes 2007
Novel insights in the immune function of the vitamin D system: Synergism with interferon-beta
E Etten, C Gysemans, DD Branisteanu, A Verstuyf, R Bouillon, L Overbergh, C Mathieu
The Journal of Steroid Biochemistry and Molecular Biology 2007
Vitamin D levels in people with multiple sclerosis and community controls in Tasmania, Australia
IA Mei, AL Ponsonby, T Dwyer, L Blizzard, BV Taylor, T Kilpatrick, H Butzkueven, AJ McMichael
Journal of Neurology 2007
Risk factors in the development of multiple sclerosis
KL Munger, A Ascherio
Expert Review of Clinical Immunology 2007
Environmental risk factors for multiple sclerosis. Part II: Noninfectious factors
A Ascherio, KL Munger
Annals of Neurology 2007
Control of T Cell-mediated Autoimmunity by Metabolite Flux to N -Glycan Biosynthesis
A Grigorian, SU Lee, W Tian, IJ Chen, G Gao, R Mendelsohn, JW Dennis, M Demetriou
The Journal of biological chemistry 2007
Safety of vitamin D3 in adults with multiple sclerosis
SM Kimball, MR Ursell, P O'Connor, R Vieth
The American journal of clinical nutrition 2007
The Biology of Dendritic Cells and HIV Infection
S Gessani, F Belardelli
2007
1,25-Dihydroxyvitamin D3 inhibits lipopolysaccharide-induced immune activation in human endothelial cells
O Equils, Y Naiki, AM Shapiro, K Michelsen, D Lu, J Adams, S Jordan
Clinical & Experimental Immunology 2006
Interaction among vitamin D3 analogue KH 1060, TNF-α, and vitamin D receptor protein in peripheral blood mononuclear cells of inflammatory bowel disease patients
M Stio, M Martinesi, S Bruni, C Treves, G d'Albasio, S Bagnoli, AG Bonanomi
International Immunopharmacology 2006
IL-10 Signaling Is Essential for 1,25-Dihydroxyvitamin D 3 -Mediated Inhibition of Experimental Autoimmune Encephalomyelitis
KM Spach, FE Nashold, BN Dittel, CE Hayes
Journal of immunology (Baltimore, Md. : 1950) 2006
Hypercalcemia produced by parathyroid hormone suppresses experimental autoimmune encephalomyelitis in female but not male mice
TF Meehan, J Vanhooke, J Prahl, HF DeLuca
Archives of Biochemistry and Biophysics 2005
Vitamin D3 confers protection from autoimmune encephalomyelitis only in female mice
KM Spach, CE Hayes
Journal of immunology (Baltimore, Md. : 1950) 2005
22-ene-25-oxa-vitamin D: a new vitamin D analogue with profound immunosuppressive capacities
C Daniel, T Schlauch, U Zugel, A Steinmeyer, HH Radeke, D Steinhilber, J Stein
European Journal of Clinical Investigation 2005
The role of vitamin D in protecting type 1 diabetes mellitus
K Luong, LT Nguyen, DN Nguyen
Diabetes/Metabolism Research and Reviews 2005
Immunomodulating effects of vitamin D analogs in hemodialysis patients
E Seibert, NW Levin, MK Kuhlmann
Hemodialysis International 2005
Immunoregulation by 1,25-dihydroxyvitamin D3: Basic concepts
E Etten, C Mathieu
The Journal of Steroid Biochemistry and Molecular Biology 2005
Intervention in autoimmunity: The potential of vitamin D receptor agonists
L Adorini
Cellular Immunology 2005
Calcium and 1?,25-dihydroxyvitamin?D3 target the TNF-? pathway to suppress experimental inflammatory bowel disease
Y Zhu, BD Mahon, M Froicu, MT Cantorna
European Journal of Immunology 2005
Vitamin D Receptor Polymorphisms are Associated with Graves' Disease in German and Polish But not in Serbian Patients
E Ramos-Lopez, A Kurylowicz, T Bednarczuk, J Paunkovic, C Seidl, K Badenhoop
Thyroid 2005
Mucosal Immunology
WR Brown
Mucosal Immunology 2005
Heterogeneity of vitamin D receptor gene association with celiac disease and type 1 diabetes mellitus
JI Pedro, JR Bilbao, GP de Nanclares, JC Vitoria, P Martul, L Castaño
Autoimmunity 2005
Treatment with 1, 25-Dihydroxyvitamin D3 Preserves Glomerular Slit Diaphragm-Associated Protein Expression in Experimental Glomerulonephritis
M Migliori, L Giovannini, V Panichi, C Filippi, D Taccola, N Origlia, C Mannari, G Camussi
International journal of immunopathology and pharmacology 2005
25-Hydroxyvitamin D levels in serum at the onset of multiple sclerosis
M Soilu-Hänninen, L Airas, I Mononen, A Heikkilä, M Viljanen, A Hänninen
Multiple sclerosis (Houndmills, Basingstoke, England) 2005
Transcriptional Profiling of γδ T Cells Identifies a Role for Vitamin D in the Immunoregulation of the Vγ9Vδ2 Response to Phosphate-Containing Ligands
L Chen, MT Cencioni, DF Angelini, G Borsellino, L Battistini, CF Brosnan
Journal of immunology (Baltimore, Md. : 1950) 2005
Micronutrients and the Risk of Type 1 Diabetes: Vitamin D, Vitamin E, and Nicotinamide
E Hypponen
Nutrition Reviews 2004
Prediabetes: prediction and prevention trials
F Vendrame, PA Gottlieb
Endocrinology & Metabolism Clinics of North America 2004
CYP27B1 polymorphisms variants are associated with type 1 diabetes mellitus in Germans
ER Lopez, K Regulla, MA Pani, M Krause, KH Usadel, K Badenhoop
The Journal of Steroid Biochemistry and Molecular Biology 2004
Immunoendocrinology in Health and Disease
N Martens, E Hooghe-Peters, R Hooghe
Immunoendocrinology in Health and Disease 2004
Gene expression analysis suggests that 1,25-dihydroxyvitamin D 3 reverses experimental autoimmune encephalomyelitis by stimulating inflammatory cell apoptosis
KM Spach, LB Pedersen, FE Nashold, T Kayo, BS Yandell, TA Prolla, CE Hayes
Physiological genomics 2004
Multiple sclerosis and vitamin D: an update
BM VanAmerongen, CD Dijkstra, P Lips, CH Polman
European Journal of Clinical Nutrition 2004
Effect of Anti-TNF Therapy and Vitamin D Derivatives on the Proliferation of Peripheral Blood Mononuclear Cells in Crohn's Disease
M Stio, C Treves, M Martinesi, G d'Albasio, S Bagnoli, AG Bonanomi
Digestive Diseases and Sciences 2004
VITAMINDAND ITSANALOGS ASREGULATORS OFIMMUNEACTIVATION ANDANTIGENPRESENTATION
MD Griffin, N Xing, R Kumar
Annual Review of Nutrition 2003
The pleiotropic actions of vitamin D
R Lin, JH White
BioEssays 2003
New insights into the mechanisms of vitamin D action
S Christakos, P Dhawan, Y Liu, X Peng, A Porta
Journal of Cellular Biochemistry 2003
Treatment of experimental autoimmune encephalomyelitis in rat by 1,25-dihydroxyvitamin D3 leads to early effects within the central nervous system
E Garcion, L Sindji, S Nataf, P Brachet, F Darcy, CN Montero-Menei
Acta Neuropathologica 2003
Role of Hypolipidemic Drug Clofibrate in Altering Iron Regulatory Proteins IRP1 and IRP2 Activities and Hepatic Iron Metabolism in Rats Fed a Low-Iron Diet
HL Huang, NS Shaw
Toxicology and Applied Pharmacology 2002
CD8(+) T cells are not necessary for 1 alpha,25-dihydroxyvitamin D(3) to suppress experimental autoimmune encephalomyelitis in mice
TF Meehan, HF DeLuca
Proceedings of the National Academy of Sciences 2002
A Novel Immunosuppressive 1alpha,25-Dihydroxyvitamin D3 Analog with Reduced Hypercalcemic Activity
U Zugel, A Steinmeyer, C Giesen, K Asadullah
Journal of Investigative Dermatology 2002
The coming of age of 1,25-dihydroxyvitamin D3 analogs as immunomodulatory agents
C Mathieu, L Adorini
Trends in Molecular Medicine 2002
New clues about vitamin D functions in the nervous system
E Garcion, N Wion-Barbot, CN Montero-Menei, F Berger, D Wion
Trends in Endocrinology & Metabolism 2002
Retinoic acid promotes the development of Th2-like human myelin basic protein-reactive T cells
AE Lovett-Racke, MK Racke
Cellular Immunology 2002
Immunomodulatory effects of vitamin D receptor ligands in autoimmune diseases
L Adorini
International Immunopharmacology 2002
The vitamin D receptor is necessary for 1α,25-dihydroxyvitamin D3 to suppress experimental autoimmune encephalomyelitis in mice
TF Meehan, HF DeLuca
Archives of Biochemistry and Biophysics 2002
A 1 ,25-Dihydroxyvitamin D3 Analog Enhances Regulatory T-Cells and Arrests Autoimmune Diabetes in NOD Mice
S Gregori, N Giarratana, S Smiroldo, M Uskokovic, L Adorini
Diabetes 2002
Effects of 1α,25(OH) 2 D 3 and its analogs on dendritic cell function: 1α,25(OH) 2 D 3 and Dendritic Cells
MD Griffin, R Kumar
Journal of Cellular Biochemistry 2002
Vitamin D and autoimmune diabetes: Vitamin D and Autoimmune Diabetes
JB Zella, HF DeLuca
Journal of Cellular Biochemistry 2002
Association of vitamin D receptor gene BsmI polymorphisms in Chinese patients with systemic lupus erythematosus
CM Huang, MC Wu, JY Wu, FJ Tsai
Lupus 2002
1,25-Dihydroxyvitamin D 3 Inhibits IFN-γ and IL-4 Levels During In Vitro Polarization of Primary Murine CD4 + T Cells
TP Staeva-Vieira, LP Freedman
Journal of immunology (Baltimore, Md. : 1950) 2002
Vitamin D3 and Its Synthetic Analogs Inhibit the Spontaneous in Vitro Immunoglobulin Production by SLE-Derived PBMC
M Linker-Israeli, E Elstner, JR Klinenberg, DJ Wallace, HP Koeffler
Clinical Immunology 2001
Dendritic cell modulation by 1alpha,25 dihydroxyvitamin D3 and its analogs: a vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro and in vivo
MD Griffin, W Lutz, VA Phan, LA Bachman, DJ McKean, R Kumar
Proceedings of the National Academy of Sciences 2001
Effects of 1,25(OH)2D3 in experimental mesangial proliferative nephritis in rats
V Panichi, M Migliori, D Taccola, C Filippi, LD Nisco, L Giovannini, R Palla, C Tetta, G Camussi
Kidney International 2001
Influence of vitamin D receptor gene polymorphisms on mortality risk in hemodialysis patients
MP Marco, L Craver, A Betriu, J Fibla, E Fernández
American Journal of Kidney Diseases 2001
1α,25-Dihydroxyvitamin D3 Has a Direct Effect on Naive CD4 + T Cells to Enhance the Development of Th2 Cells
A Boonstra, FJ Barrat, C Crain, VL Heath, HF Savelkoul, A OGarra
Journal of immunology (Baltimore, Md. : 1950) 2001
Influence of cholecalciferol (vitamin D3) on the course of experimental systemic lupus erythematosus in F1 (NZBxW) mice
MW Vaisberg, R Kaneno, MF Franco, NF Mendes
Journal of Clinical Laboratory Analysis 2000
1,25-Dihydroxyvitamin D3 treatment decreases macrophage accumulation in the CNS of mice with experimental autoimmune encephalomyelitis
FE Nashold, DJ Miller, CE Hayes
Journal of Neuroimmunology 2000
Potent Inhibition of Dendritic Cell Differentiation and Maturation by Vitamin D Analogs
MD Griffin, WH Lutz, VA Phan, LA Bachman, DJ McKean, R Kumar
Biochemical and Biophysical Research Communications 2000
Recent developments in the use of vitamin D analogues
A Verstuyf, S Segaert, L Verlinden, R Bouillon, C Mathieu
Expert Opinion on Investigational Drugs 2000
Rat oligodendrocytes express the vitamin D3 receptor and respond to 1,25-dihydroxyvitamin D3
D Baas, K Pr�fer, ME Ittel, S Kuchler-Bopp, G Labourdette, LL Sarli�ve, P Brachet
Glia 2000
Vitamin D and Autoimmunity: Is Vitamin D Status an Environmental Factor Affecting Autoimmune Disease Prevalence?
MT Cantorna
Proceedings of the Society for Experimental Biology and Medicine 2000
Vitamin D: a natural inhibitor of multiple sclerosis
CE Hayes
Proceedings of the Nutrition Society 2000
Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles
M Niino, T Fukazawa, I Yabe, S Kikuchi, H Sasaki, K Tashiro
Journal of the Neurological Sciences 2000
Expression of 1,25-Dihydroxyvitamin D3 Receptor in the Immune System
CM Veldman, MT Cantorna, HF DeLuca
Archives of Biochemistry and Biophysics 2000
ANALOGS OF 1,25-DIHYDROXYVITAMIN D 3 AS DOSE-REDUCING AGENTS FOR CLASSICAL IMMUNOSUPPRESSANTS12:
E van Etten, DD Branisteanu, A Verstuyf, M Waer, R Bouillon, C Mathieu
Transplantation 2000
1,25-Dihydroxycholecalciferol Prevents and Ameliorates Symptoms of Experimental Murine Inflammatory Bowel Disease
MT Cantorna, C Munsick, C Bemiss, BD Mahon
The Journal of nutrition 2000
Neuro-Immune Interactions in Neurologic and Psychiatric Disorders
P Patterson, C Kordon, Y Christen
2000
1α,25-Dihydroxyvitamin D 3 Inhibits Differentiation, Maturation, Activation, and Survival of Dendritic Cells Leading to Impaired Alloreactive T Cell Activation
G Penna, L Adorini
Journal of immunology (Baltimore, Md. : 1950) 2000
Influence of cholecalciferol (vitamin D3) on the course of experimental systemic lupus erythematosus in F1 (NZBxW) mice
Vaisberg MW, Kaneno R, Franco MF, Mendes NF
Journal of Clinical Laboratory Analysis 2000
Autocrine control of vitamin D metabolism in synovial cells from arthritic patients
SJ Smith, ME Hayes, PL Selby, EB Mawer
Annals of the rheumatic diseases 1999
Association of vitamin D receptor gene polymorphism with multiple sclerosis in Japanese
T Fukazawa, I Yabe, S Kikuchi, H Sasaki, T Hamada, K Miyasaka, K Tashiro
Journal of the Neurological Sciences 1999
Dietary Calcium Is a Major Factor in 1,25-Dihydroxycholecalciferol Suppression of Experimental Autoimmune Encephalomyelitis in Mice
MT Cantorna, J Humpal-Winter, HF DeLuca
The Journal of nutrition 1999
Inhibition of IL-12 production by 1,25-dihydroxyvitamin D3. Involvement of NF-kappaB downregulation in transcriptional repression of the p40 gene
D D'Ambrosio, M Cippitelli, MG Cocciolo, D Mazzeo, PD Lucia, R Lang, F Sinigaglia, P Panina-Bordignon
Journal of Clinical Investigation 1998
A vitamin D analogue (MC 1288) has immunomodulatory properties and suppresses collagen-induced arthritis (CIA) without causing hypercalcaemia
P Larsson, L Mattsson, L Klareskog, C Johnsson
Clinical & Experimental Immunology 1998
Expression of inducible nitric oxide synthase during rat brain inflammation: Regulation by 1,25-dihydroxyvitamin D3
E Garcion, L Sindji, C Montero-Menei, C Andre, P Brachet, F Darcy
Glia 1998
Calcitriol modulates in vivo and in vitro cytokine production: A role for intracellular calcium
V Panichi, SD Pietro, B Andreini, AM Bianchi, M Migliori, D Taccola, L Giovannini, C Tetta, R Palla
Kidney International 1998
Effect of 1,25(OH)2 vitamin D3 on glomerulosclerosis in subtotally nephrectomized rats
U Schwarz, K Amann, SR Orth, A Simonaviciene, S Wessels, E Ritz
Kidney International 1998
Neuroinflammation
PL Wood
Neuroinflammation 1998
The effect of 1,25(OH)2 vitamin D3 on subsets of T lymphocytes in postmenopausal women
I Žofková, RL Kancheva
Life Sciences 1997
1,25-Dihydroxyvitamin D3 inhibits the expression of inducible nitric oxide synthase in rat central nervous system during experimental allergic encephalomyelitis
E Garcion, S Nataf, A Berod, F Darcy, P Brachet
Brain research. Molecular brain research 1997
A VITAMIN D ANALOG, MC1288, INHIBITS ADVENTITIAL INFLAMMATION AND SUPPRESSES INTIMAL LESIONS IN RAT AORTIC ALLOGRAFTS:
AK Risnen-Sokolowski, IS Pakkala, SP Samila, L Binderup, PJ Hyry, NA Pakkala
Transplantation 1997
Effect of 1,25-dihydroxyvitamin D3 on mouse thymus: role of extracellular calcium
M Mohamed
Biochimica et Biophysica Acta (BBA) - General Subjects 1996
Vitamin D Analogues in Insulin-Dependent Diabetes Mellitus and Other Autoimmune Diseases: A Therapeutic Perspective
D Mauricio, T Mandrup-Poulsen, J Nerup
Diabetes/Metabolism Reviews 1996
1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis
MT Cantorna, CE Hayes, HF DeLuca
Proceedings of the National Academy of Sciences 1996
Induction of common mucosal immunity by hormonally immunomodulated peripheral immunization
RA Daynes, EY Enioutina, S Butler, HH Mu, ZA McGee, AA B
Infection and immunity 1996
Experimental allergic encephalomyelitis in the rat is inhibited by aminoguanidine, an inhibitor of nitric oxide synthase
W Zhao, RG Tilton, JA Corbett, ML McDaniel, TP Misko, JR Williamson, AH Cross, WF Hickey
Journal of Neuroimmunology 1996
Combination of Vitamin D Analogues and Immunosuppressants: Potential Clinical Use
DD Branisteanu, C Mathieu, K Casteels, R Bouillon
Clinical immunotherapeutics 1996
Immunomodulatory actions of 1,25-Dihydroxyvitamin D3
JM Lemire
The Journal of Steroid Biochemistry and Molecular Biology 1995
Optimal concentration of tacalcitol in once-daily treatment of psoriasis
O Baadsgaard, J Traulsen, J Roed-Petersen, H Jakobsen
Journal of Dermatological Treatment 1995
Advances in Drug Research
CL Crespi
Advances in Drug Research 1995
Non-hypercalcemic pharmacological aspects of vitamin D analogs
R Bouillon, A Verstuyf, L Verlinden, K Allewaert, D Branisteanu, C Mathieu, HV Baelen
Biochemical Pharmacology 1995
Treating tumor-bearing mice with vitamin D3 diminishes tumor-induced myelopoiesis and associated immunosuppression, and reduces tumor metastasis and recurrence
MR Young, J Ihm, Y Lozano, MA Wright, MM Prechel
Cancer Immunology, Immunotherapy 1995
Effects of In Vivo Administration of 1,25-Dihydroxyvitamin D3 on In Vitro Proliferation of Bovine Lymphocytes1
FG Hustmyer, DC Beitz, JP Goff, BJ Nonnecke, RL Horst, TA Reinhardt
Journal of Dairy Science 1994
MC 1288 - A vitamin D analogue with immunosuppressive effects on heart and small bowel grafts
C Johnsson, G Tufveson
Transplant International 1994
MC 1288 ? A vitamin D analogue with immunosuppressive effects on heart and small bowel grafts
C Johnsson, G Tufveson
Transplant International 1994
Prevention of autoimmune diabetes in NOD mice by 1,25 dihydroxyvitamin D3
C Mathieu, M Waer, J Laureys, O Rutgeerts, R Bouillon
Diabetologia 1994
Effects of two new vitamin D3 derivatives, 22-oxa-1α-25-dihydroxyvitamin D3 (OCT) and 2β-(3-hydroxypropoxy)-1α,25-dihydroxyvitamin D3 (ED-71), on bone metabolism in organ culture
K Sato, Y Nishii, FN Woodiel, LG Raisz
Bone 1993
Partial prevention of active Heymann nephritis by 1 alpha, 25 dihydroxyvitamin D3
DD Branisteanu, P Leenaerts, B Damme, R Bouillon
Clinical & Experimental Immunology 1993
Partial prevention of active Heymann nephritis by lα, 25 dihydroxyvitamin D3
DD Branisteanu, P Leenaerts, B Damme, R Bouillon
Clinical & Experimental Immunology 1993
Physiological Actions and Clinical Applications of Transforming Growth Factor-β (TGF-β)
AB Roberts, MB Sporn
Growth Factors 1993
Immunomodulatory role of 1,25-dihydroxyvitamin D3
JM Lemire
Journal of Cellular Biochemistry 1992
1,25-Dihydroxyvitamin D3 inhibits the passive transfer of cellular immunity by a myelin basic protein-specific T cell clone
JM Lemire, JS Adams
Journal of Bone and Mineral Research 1992
1,25-Dihydroxyvitamin D3Attenuates of Expression of Experimental Murine Lupus of MRL/1 Mice
JM Lemire, A Ince, M Takashima
Autoimmunity 1992
Potential role of prostaglandins and leukotrienes in multiple sclerosis and experimental allergic encephalomyelitis
DJ Fretland
Prostaglandins Leukotrienes and Essential Fatty Acids 1992
Vitamin neurotoxicity
SR Snodgrass
Molecular Neurobiology 1992
1,25-Dihydroxyvitamin D3 enhances the generation of nonspecific suppressor cells while inhibiting the induction of cytotoxic cells in a human MLR
MA Meehan, RH Kerman, JM Lemire
Cellular Immunology 1992
Immunological properties of vitamin D analogues and metabolites
L Binderup
Biochemical Pharmacology 1992
Vitamin D
A Portale, Β Halloran, E Lonergan, R Morris
Vitamin D 1988

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