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Metabolic effects of cachectin/tumor necrosis factor are modified by site of production. Cachectin/tumor necrosis factor-secreting tumor in skeletal muscle induces chronic cachexia, while implantation in brain induces predominantly acute anorexia.

K J Tracey, … , K R Manogue, A Cerami

K J Tracey, … , K R Manogue, A Cerami

Published December 1, 1990
Citation Information: J Clin Invest. 1990;86(6):2014-2024. https://doi.org/10.1172/JCI114937.

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