JCI - Citations to Insulin-like growth factor I expression by tumors of neuroectodermal origin with the t(11;22) chromosomal translocation. A potential autocrine growth factor.

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Insulin-like growth factor I expression by tumors of neuroectodermal origin with the t(11;22) chromosomal translocation. A potential autocrine growth factor.

D Yee, … , C P Reynolds, N Rosen

D Yee, … , C P Reynolds, N Rosen

Published December 1, 1990
Citation Information: J Clin Invest. 1990;86(6):1806-1814. https://doi.org/10.1172/JCI114910.

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Shifting from a Biological-Agnostic Approach to a Molecular-Driven Strategy in Rare Cancers: Ewing Sarcoma Archetype. Caltavituro A, Buonaiuto R, Pietroluongo E, Morra R, Salomone F, De Placido P, Pagliuca M, Vaia A, Ottaviano M, Tortora M, De Placido S, Palmieri G, Giuliano M	Biomedicines	2023
Redundant Signaling as the Predominant Mechanism for Resistance to Antibodies Targeting the Type-I Insulin-Like Growth Factor Receptor in Cells Derived from Childhood Sarcoma. Shackleford TJ, Hariharan S, Vaseva AV, Alagoa K, Espinoza M, Bid HK, Li F, Zhong H, Phelps DA, Roberts RD, Cam H, London CA, Guttridge DC, Chen Y, Rao M, Shiio Y, Houghton PJ	Molecular cancer therapeutics	2023
Randomized Phase III Trial of Ganitumab With Interval-Compressed Chemotherapy for Patients With Newly Diagnosed Metastatic Ewing Sarcoma: A Report From the Children's Oncology Group. DuBois SG, Krailo MD, Glade-Bender J, Buxton A, Laack N, Randall RL, Chen HX, Seibel NL, Boron M, Terezakis S, Hill-Kayser C, Hayes A, Reid JM, Teot L, Rakheja D, Womer R, Arndt C, Lessnick SL, Crompton BD, Kolb EA, Daldrup-Link H, Eutsler E, Reed DR, Janeway KA, Gorlick RG	Journal of Clinical Oncology	2023
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Targeted Therapy in Bone and Soft Tissue Sarcoma in Children and Adolescents PA Thompson, M Chintagumpala	Current Oncology Reports	2012
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Small Is Beautiful: Insulin-Like Growth Factors and Their Role in Growth, Development, and Cancer RG Maki	Journal of Clinical Oncology	2010
Laron Syndrome - From Man to Mouse Z Laron, J Kopchick		2010
Molecularly Targeted Therapy for Childhood Cancer PJ Houghton, RJ Arceci		2010
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Development of IGF-IR inhibitors in pediatric sarcomas EA Kolb, R Gorlick	Current Oncology Reports	2009
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Anti-insulin growth factor receptor therapy in Ewing sarcoma MS Isakoff, N Marina	F1000 medicine reports	2009
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Phase I, Pharmacokinetic, and Pharmacodynamic Study of AMG 479, a Fully Human Monoclonal Antibody to Insulin-Like Growth Factor Receptor 1 AW Tolcher, J Sarantopoulos, A Patnaik, K Papadopoulos, CC Lin, J Rodon, B Murphy, B Roth, I McCaffery, KS Gorski, B Kaiser, M Zhu, H Deng, G Friberg, I Puzanov	Journal of Clinical Oncology	2009
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IGF-1 Receptor Inhibitors in Clinical Trials—Early Lessons SJ Weroha, P Haluska	Journal of Mammary Gland Biology and Neoplasia	2008
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Late Recurrence of Ewing Sarcoma During Pregnancy SG DuBois, AR Perez-Atayde, TW McLean, HE Grier	Journal of Pediatric Hematology/Oncology	2008
IGF signaling as a therapeutic target in pediatric solid tumors of the central and peripheral nervous system MA Grotzer, AS Guerreiro, JP Bourquin, A Arcaro	Expert Review of Endocrinology & Metabolism	2007
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The Biology of Ewing sarcoma N Riggi, I Stamenkovic	Cancer Letters	2007
Patients with congenital deficiency of IGF-I seem protected from the development of malignancies: A preliminary report O Shevah, Z Laron	Growth Hormone & IGF Research	2007
Regulation of apoptosis and proliferation in Ewing's sarcoma—opportunities for targeted therapy U Kontny	Hematological Oncology	2006
Kompendium Internistische Onkologie HJ Schmoll, K Höffken, K Possinger		2006
The Potential for molecular therapeutic targets in Ewing’s sarcoma NR McAllister, SL Lessnick	Current Treatment Options in Oncology	2005
Ewing’s sarcoma family of tumors MJ García	Clinical and Translational Oncology	2005
Insulin-like growth factor 1 signaling in human gastrointestinal carcinoid tumor cells JJ van Gompel, H Chen	Surgery	2004
Basic Fibroblast Growth Factor-induced Cell Death Is Effected through Sustained Activation of p38 MAPK and Up-regulation of the Death Receptor p75 NTR AJ Williamson, BC Dibling, JR Boyne, P Selby, SA Burchill	The Journal of biological chemistry	2004
Contribution of MEK/MAPK and PI3-K signaling pathway to the malignant behavior of Ewing's sarcoma cells: Therapeutic prospects S Benini, MC Manara, V Cerisano, S Perdichizzi, R Strammiello, M Serra, P Picci, K Scotlandi	International Journal of Cancer	2003
Handbook of Cell Signaling MF White	Handbook of Cell Signaling	2003
Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells A Üren, MS Merchant, CJ Sun, MI Vitolo, Y Sun, M Tsokos, PB Illei, M Ladanyi, A Passaniti, C Mackall, JA Toretsky	Oncogene	2003
Anchorage-independent multi-cellular spheroids as an in vitro model of growth signaling in Ewing tumors ER Lawlor, C Scheel, J Irving, PH Sorensen	Oncogene	2002
Effectiveness of insulin-like growth factor I receptor antisense strategy against Ewing's sarcoma cells K Scotlandi, C Maini, MC Manara, S Benini, M Serra, V Cerisano, R Strammiello, N Baldini, PL Lollini, P Nanni, G Nicoletti, P Picci	Cancer Gene Therapy	2002
Expression of an IGF-I receptor dominant negative mutant induces apoptosis, inhibits tumorigenesis and enhances chemosensitivity in Ewing's sarcoma cells K Scotlandi, S Avnet, S Benini, MC Manara, M Serra, V Cerisano, S Perdichizzi, PL Lollini, CD Giovanni, L Landuzzi, P Picci	International Journal of Cancer	2002
Human Cell Culture MR Koller, BO Palsson, JR Masters		2002
Insulin-like growth factor type 1 (IGF-1) and IGF binding protein-3 in patients with Ewing sarcoma family of tumors JA Toretsky, SM Steinberg, M Thakar, D Counts, BP B.A., CP B.A., A Eskenazi, L Helman, LH Wexler	Cancer	2001
Regulation of glutamine transport by the type I insulin-like growth factor receptor in a human neuroblastoma cell line HS Wang, M Wasa, A Okada	Cancer Letters	2001
Sensitivity of Ewing's sarcoma to TRAIL-induced apoptosis HU Kontny, K Hämmerle, R Klein, P Shayan, CL Mackall, CM Niemeyer	Cell Death and Differentiation	2001
Association of EWS-FLI1 type 1 fusion with lower proliferative rate in Ewing's sarcoma E Alava, A Panizo, CR Antonescu, AG Huvos, FJ Pardo-Mindán, FG Barr, M Ladanyi	The American Journal of Pathology	2000
A link between basic fibroblast growth factor (bFGF) and EWS/FLI-1 in Ewing's sarcoma cells L Girnita, A Girnita, M Wang, JM Meis-Kindblom, LG Kindblom, O Larsson	Oncogene	2000
Regulation of the human poly(ADP-ribose) polymerase promoter by the ETS transcription factor VA Soldatenkov, A Albor, BK Patel, R Dreszer, A Dritschilo, V Notario	Oncogene	1999
The role of insulin-like growth factor system in soft tissue sarcomas: from physiopathology to targeted therapeutic approaches W Zumkeller	Sarcoma	1998
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Growth Factors and Cytokines in Health and Disease P Martin, J McCluskey, P Mallucci, S Nodder	Growth Factors and Cytokines in Health and Disease	1997
The Insulin-like Growth Factor-I Receptor Is Required for EWS/FLI-1 Transformation of Fibroblasts JA Toretsky, T Kalebic, V Blakesley, D LeRoith, LJ Helman	The Journal of biological chemistry	1997
Olfactory neuroblastoma is a peripheral primitive neuroectodermal tumor related to Ewing sarcoma PH Sorensen, JK Wu, KW Berean, JF Lim, W Donn, HF Frierson, CP Reynolds, D López-Terrada, TJ Triche	Proceedings of the National Academy of Sciences	1996
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Induction of Cardiac Insulin-Like Growth Factor I Gene Expression in Pressure Overload Hypertrophy MC Hanson, KA Fath, RW Alexander, P Delafontaine	The American Journal of the Medical Sciences	1993
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Discussion: Gut Neuroendocrine Disease H Ahlman	The Yale journal of biology and medicine	1992
Type I and type II insulin-like growth factor receptors and their function in human Ewing's sarcoma cells F van Valen, W Winkelmann, H Jürgens	Journal of Cancer Research and Clinical Oncology	1992
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