Acidic and basic fibroblast growth factors (aFGF and bFGF) are angiogenic polypeptide mitogens for cells of mesodermal and neuroectodermal origin. In this report we describe the purification from several normal human hearts (including a very fresh, nonischemic sample) of heparin-binding, acid-, heat- and trypsin-sensitive 14-18-kD peptides that crossreact with antisera against aFGF and bFGF. Further evidence includes (a) prevention of mitogenicity by protamine and by anti-bFGF, (b) displacement of 125I-bFGF from cell membranes, and (c) stimulation of capillary endothelial cell migration. Specific immunohistochemistry localized bFGF to endothelial cells and, surprisingly, to cardiac myocytes, with almost no immunoreactivity in smooth muscle cells. These peptides may function in cardiac embryogenesis, hypertrophy, atherogenesis, angiogenesis, and wound healing, and may also have endocrine, neurotropic, or vasomotor functions.
W Casscells, E Speir, J Sasse, M Klagsbrun, P Allen, M Lee, B Calvo, M Chiba, L Haggroth, J Folkman
Title and authors | Publication | Year |
---|---|---|
Cardiac actions of fibroblast growth factor 23
C Faul |
Bone | 2016 |
Advanced Interfere Treatment of Diabetic Cardiomyopathy Rats by aFGF-Loaded Heparin-Modified Microbubbles and UTMD Technique
M Zhang, WZ Yu, XT Shen, Q Xiang, J Xu, JJ Yang, PP Chen, ZL Fan, J Xiao, YZ Zhao, CT Lu |
Cardiovascular Drugs and Therapy | 2016 |
Therapeutic neovascularization for coronary disease: current state and future prospects
AD Lassaletta, LM Chu, FW Sellke |
Basic Research in Cardiology | 2011 |
Advances in Cancer Research
M Lemaire, S Deleu, ED Bruyne, EV Valckenborgh, E Menu, K Vanderkerken |
Advances in Cancer Research Volume 110 | 2011 |
The Most Important Angiogenic Growth Factors Influencing the Development and Function of Blood Vessels - in the Context of Coronary Artery Bypass Grafting (CABG)
K Sterzynska, P Sujka-Kordowska, W Witkiewicz |
Advances in Cell Biology | 2011 |
Ultrastructural immunolocalization of basic fibroblast growth factor in endothelial cells: morphologic evidence for unconventional secretion of a novel protein
RG Aktas, RJ Kayton |
Journal Of Molecular Histology | 2011 |
Angiogenesis
TH Adair, JP Montani |
Colloquium Series on Integrated Systems Physiology: From Molecule to Function | 2010 |
Therapeutic Angiogenesis in Diabetes and Hypercholesterolemia: Influence of Oxidative Stress
M Boodhwani, FW Sellke |
Antioxidants & Redox Signaling | 2009 |
Polymorphisms in the Promoter Region of the Basic Fibroblast Growth Factor Gene Are Not Associated with Myocardial Infarction in a Slovene Population with Type 2 Diabetes
S Kariž, D Grabar, M Krkovič, J Osredkar, D Petrovič |
J INT MED RES | 2009 |
Neurotrophic Factors in Autonomic Nervous System Plasticity and Dysfunction
MP Mattson, R Wan |
NeuroMolecular Medicine | 2008 |
Extrinsic regulation of T-type Ca2+ channel expression in chick nodose ganglion neurons
J Pachuau, M Martin-Caraballo |
Developmental Neurobiology | 2007 |
THE FUTURE OF THERAPEUTIC MYOCARDIAL ANGIOGENESIS
M Boodhwani, NR Sodha, RJ Laham, FW Sellke |
Shock | 2006 |
Impaired myocardial capillarogenesis and increased adaptive capillary growth in FGF2-deficient mice
K Amann, J Faulhaber, V Campean, V Balajew, R Dono, G Mall, H Ehmke |
Laboratory Investigation | 2005 |
Long-term Therapy with the Acorn Cardiac Support Device Normalizes Gene Expression of Growth Factors and Gelatinases in Dogs with Heart Failure
S Rastogi, RC Gupta, S Mishra, H Morita, EJ Tanhehco, HN Sabbah |
The Journal of Heart and Lung Transplantation | 2005 |
Intracoronary administration of FGF-2: a computational model of myocardial deposition and retention
RJ Filion, AS Popel |
American journal of physiology. Heart and circulatory physiology | 2005 |
Concentrations of Hepatocyte Growth Factor, Basic Fibroblast Growth Factor, and Vascular Endothelial Growth Factor in Pericardial Fluid and Plasma
T Kubota, A Namiki, M Fukazawa, M Ishikawa, M Moroi, K Ebine, T Yamaguchi |
Japanese Heart Journal | 2004 |
Therapeutic angiogenesis for myocardial ischemia
A Rosinberg, TA Khan, FW Sellke, RJ Laham |
Expert Review of Cardiovascular Therapy | 2004 |
Cyclin A2 Mediates Cardiomyocyte Mitosis in the Postmitotic Myocardium
HW Chaudhry, NH Dashoush, H Tang, L Zhang, X Wang, EX Wu, DJ Wolgemuth |
The Journal of biological chemistry | 2004 |
Arteriogenesis
W Schaper, J Schaper |
2004 | |
Contrast Echocardiography in Clinical Practice
JL Zamorano, MA Fernández |
2004 | |
STRESS-ACTIVATEDCYTOKINES ANDTHEHEART: From Adaptation to Maladaptation1
DL Mann |
Annual Review of Physiology | 2003 |
Therapeutic angiogenesis: review of current concepts and future directions
W Abo-Auda, RL Benza |
The Journal of Heart and Lung Transplantation | 2003 |
Invasive and non-invasive evaluation of spontaneous arteriogenesis in a novel porcine model for peripheral arterial obstructive disease
IR Buschmann, M Voskuil, N Royen, IE Hoefer, K Scheffler, S Grundmann, J Hennig, W Schaper, C Bode, JJ Piek |
Atherosclerosis | 2003 |
Peripheral monocytes from diabetic patients with coronary artery disease display increased bFGF and VEGF mRNA expression
D Panutsopulos, A Zafiropoulos, E Krambovitis, GE Kochiadakis, NE Igoumenidis, DA Spandidos |
Journal of Translational Medicine | 2003 |
Insights from Angiogenesis Trials Using Fibroblast Growth Factor for Advanced Arteriosclerotic Disease
R Khurana, M Simons |
Trends in Cardiovascular Medicine | 2003 |
Therapeutic angiogenesis for coronary artery disease
TA Khan, FW Sellke, RJ Laham |
Current Treatment Options in Cardiovascular Medicine | 2002 |
The Yin/Yang of Innate Stress Responses in the Heart
D Mann |
Cold Spring Harbor Symposia on Quantitative Biology | 2002 |
Coronary arteriogenesis and differentiation of periarterial Purkinje fibers in the chick heart: is there a link?
BS Harris, TX O'Brien, RG Gourdie |
Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital | 2002 |
Basic fibroblast growth factor changes in response to coronary angioplasty in patients with stable angina
AA Katinioti, D Tousoulis, E Economou, C Stefanadis, A Trikas, C Tentolouris, C Pitsavos, A Androulakis, P Toutouzas |
International Journal of Cardiology | 2002 |
Myocardial Contrast Echocardiography Can Be Used to Assess the Microvascular Response to Vascular Endothelial Growth Factor-121
FS Villanueva, JA Abraham, GF Schreiner, M Csikari, D Fischer, JD Mills, U Schellenberger, BJ Koci, JS Lee |
Circulation | 2002 |
Expression of basic fibroblast growth factor (bFGF), FGF receptor 1 and FGF receptor 2 in uterine leiomyomas and myometrium during the menstrual cycle, after menopause and GnRHa treatment*: Is bFGF involved in growth regulation of uterine leiomyomas?
X Wu, A Blanck, M Olovsson, B Möller, B Lindblom |
Acta Obstetricia et Gynecologica Scandinavica | 2001 |
Intracoronary basic fibroblast growth factor (FGF-2) in patients with severe ischemic heart disease: results of a Phase I open-label dose escalation study
RJ Laham, NA Chronos, M Pike, ME Leimbach, JE Udelson, JD Pearlman, RI Pettigrew, MJ Whitehouse, C Yoshizawa, M Simons |
Journal of the American College of Cardiology | 2000 |
Expression of Perlecan Proteoglycan in the Infarct Zone of Mouse Myocardial Infarction
M Nakahama, T Murakami, S Kusachi, I Naito, K Takeda, H Ohnishi, I Komatsubara, T Oka, Y Ninomiya, T Tsuji |
Journal of Molecular and Cellular Cardiology | 2000 |
Pericardial Fluid From Patients With Ischemic Heart Disease Accelerates the Growth of Human Vascular Smooth Muscle Cells
T Yoneda, M Fujita, Y Kihara, K Hasegawa, T Sawamura, T Tanaka, M Inanami, R Nohara, S Sasayama |
Japanese Circulation Journal | 2000 |
Transgenic Myocardial Overexpression of Fibroblast Growth Factor-1 Increases Coronary Artery Density and Branching
B Fernandez, A Buehler, S Wolfram, S Kostin, G Espanion, WM Franz, H Niemann, PA Doevendans, W Schaper, R Zimmermann |
Circulation research | 2000 |
Therapeutic Angiogenesis: Potential Role of Basic Fibroblast Growth Factor in Patients with Severe Ischaemic Heart Disease
M Simons, RJ Laham, M Post, FW Sellke |
BioDrugs | 2000 |
Fibroblast growth factor-2 mediates pressure-induced hypertrophic response
JE Schultz, SA Witt, ML Nieman, PJ Reiser, SJ Engle, M Zhou, SA Pawlowski, JN Lorenz, TR Kimball, T Doetschman |
Journal of Clinical Investigation | 1999 |
Increased Intramural Retention After Local Delivery of Molecules with Increased Binding Properties: Implications for Regional Delivery of Pharmacologic Agents
RL Wilensky, K Mehdi, KM Sowinski, SH Baek, KL March |
Journal of cardiovascular pharmacology and therapeutics | 1999 |
Physiologically Assessed Coronary Collateral Flow and Intracoronary Growth Factor Concentrations in Patients With 1- to 3-Vessel Coronary Artery Disease
M Fleisch, M Billinger, FR Eberli, AR Garachemani, B Meier, C Seiler |
Circulation | 1999 |
Effects of Chronic Heparin Administration on Coronary Vascular Adaptation to Hypertension and Ventricular Hypertrophy in Sheep
MF Flanagan, T Aoyagi, LW Arnold, C Maute, AM Fujii, J Currier, D Bergau, HB Warren, K Rakusan |
Circulation | 1999 |
Contemporary Concepts in Cardiology
R Gorlin, G Dangas, PK Toutouzas, MM Konstadoulakis |
1999 | |
Biology of the Arterial Wall
BI Levy, A Tedgui |
1999 | |
Physical, contractile and calcium handling properties of neonatal cardiac myocytes cultured on different matrices
RJ Bick, MB Snuggs, BJ Poindexter, LM Buja, WB van Winkle |
Cell Communication and Adhesion | 1998 |
Regulation of new blood vessel growth into ischemic skeletal muscle
RL Bush, WC Pevec, A Ndoye, AT Cheung, J Sasse, DN Pearson |
Journal of Vascular Surgery | 1998 |
Advances in Organ Biology
AJ Liedtke |
Advances in Organ Biology | 1998 |
Angiogenic potential of perivascularly delivered aFGF in a porcine model of chronic myocardial ischemia
JJ Lopez, ER Edelman, A Stamler, MG Hibberd, P Prasad, KA Thomas, J Disalvo, RP Caputo, JP Carrozza, PS Douglas, FW Sellke, M Simons |
American journal of physiology. Heart and circulatory physiology | 1998 |
Repetitive coronary artery occlusions induce release of growth factors into the myocardial interstitium
D Weihrauch, J Tessmer, DC Warltier, WM Chilian |
American journal of physiology. Heart and circulatory physiology | 1998 |
Tumor Necrosis Factor-α Confers Resistance to Hypoxic Injury in the Adult Mammalian Cardiac Myocyte
M Nakano, AA Knowlton, Z Dibbs, DL Mann |
Circulation | 1998 |
Electron Microscopic Immunolocalization of Basic Fibroblast Growth Factor-Like Molecules in Capillary Endothelial Cells
RG Aktas, RJ Kayton |
Microscopy and Microanalysis | 1998 |
The Role of Angiotensin Receptors in Cardiovascular Diseases
K Helin, M Stoll, S Meffert, U Stroth, T Linger |
Annals of Medicine | 1997 |
Increased accumulation of acidic fibroblast growth factor in left ventricular myocytes of patients with idiopathic cardiomyopathy
Y Tomita, Y Kusama, Y Seino, K Munakata, H Kishida, H Hayakawa |
American Heart Journal | 1997 |
Protection of Rat Myocardium by Mitogenic and Non-Mitogenic Fibroblast Growth Factor During Post-Ischemic Reperfusion
P Cuevas, F Carceller, RM Lozano, A Crespo, M Zazo, G Giménez-Gallego |
Growth Factors | 1997 |
Adenovirus-Mediated Expression of the Secreted Form of Basic Fibroblast Growth Factor (FGF-2) Induces Cellular Proliferation and Angiogenesis In Vivo
H Ueno, JJ Li, S Masuda, Z Qi, H Yamamoto, A Takeshita |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
Hypertension and the Heart
A Zanchetti, RB Devereux, L Hansson, S Gorini |
1997 | |
Trophic Effect of Human Pericardial Fluid on Adult Cardiac Myocytes: Differential Role of Fibroblast Growth Factor-2 and Factors Related to Ventricular Hypertrophy
S Corda, A Mebazaa, MP Gandolfini, C Fitting, F Marotte, J Peynet, D Charlemagne, JM Cavaillon, D Payen, L Rappaport, JL Samuel |
Circulation research | 1997 |
Role of transiently altered sarcolemmal membrane permeability and basic fibroblast growth factor release in the hypertrophic response of adult rat ventricular myocytes to increased mechanical activity in vitro
D Kaye, D Pimental, S Prasad, T Mäki, HJ Berger, PL McNeil, TW Smith, RA Kelly |
Journal of Clinical Investigation | 1996 |
Stress activated cytokines and the heart
DL Mann |
Cytokine & Growth Factor Reviews | 1996 |
Extracellular proteolysis and the migrating vascular smooth muscle cell
RT Leeuwen |
Fibrinolysis | 1996 |
Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart
FJ Giordano, P Ping, MD McKirnan, S Nozaki, AN DeMaria, WH Dillmann, O Mathieu-Costello, HK Hammond |
Nature Medicine | 1996 |
The effect of basic fibroblast growth factor on the blood flow and morphologic features of a latissimus dorsi cardiomyoplasty
JD Mannion, V Blood, W Bailey, TL Bauer, MG Magno, F DiMeo, A Epple, FG Spinale |
The Journal of Thoracic and Cardiovascular Surgery | 1996 |
Stimulation of endothelial cells by doses of basic FGF-saporin that are lethal to smooth muscle cells
S Biro, S Shrivastav, ZX Yu, DA Lappi, A Baird, W Casscells |
Drug Delivery | 1996 |
Evidence that fibroblast growth factors 1 and 4 participate in regulation of cardiogenesis
X Zhu, J Sasse, D McAllister, J Lough |
Developmental Dynamics | 1996 |
Reduction in Myocardial Infarct Size by Basic Fibroblast Growth Factor After Temporary Coronary Occlusion in a Canine Model
MC Horrigan, AI MacIsaac, FA Nicolini, DG Vince, P Lee, SG Ellis, EJ Topol |
Circulation | 1996 |
Regulation of Angiogenesis
ID Goldberg, EM Rosen |
1996 | |
Disappearance of cyclin A correlates with permanent withdrawal of cardiomyocytes from the cell cycle in human and rat hearts
M Yoshizumi, WS Lee, CM Hsieh, JC Tsai, J Li, MA Perrella, C Patterson, WO Endege, R Schlegel, ME Lee |
Journal of Clinical Investigation | 1995 |
Stimulation of Proliferative Events in the Adult Amphibian Cardiac Myocyte
JO Oberpriller, JC Oberpriller, DG Matz, MH Soonpaa |
Annals of the New York Academy of Sciences | 1995 |
Modulation of Coronary Collateral Angiogenesis: A Canine Model of Neovascularization Induced by Chronic Ischemia
JR Kersten, DC Warltier |
Journal of Cardiac Surgery | 1995 |
Angiogenic therapy of acute myocardial infarction by intrapericardial injection of basic fibroblast growth factor and heparin sulfate: An experimental study
Y Uchida, A Yanagisawa-Miwa, F Nakamura, K Yamada, T Tomaru, K Kimura, T Morita |
American Heart Journal | 1995 |
Salutary effects of myocardial ischemia in coronary artery disease
M Fujita |
International Journal of Cardiology | 1995 |
Basic Fibroblast Growth Factor Activates Calcium Channels in Neonatal Rat Cardiomyocytes
PL Merle, JJ Feige, J Verdetti |
The Journal of biological chemistry | 1995 |
Contraction-Induced Cell Wounding and Release of Fibroblast Growth Factor in Heart
MS Clarke, RW Caldwell, H Chiao, K Miyake, PL McNeil |
Circulation research | 1995 |
Effects of Chronic Systemic Administration of Basic Fibroblast Growth Factor on Collateral Development in the Canine Heart
DF Lazarous, M Scheinowitz, M Shou, E Hodge, MA Rajanayagam, S Hunsberger, WG Robison, JA Stiber, R Correa, SE Epstein, EF Unger |
Circulation | 1995 |
Time course of growth factor staining in a rabbit model of traumatic tractional retinal detachment
I Westra, SG Robbins, DJ Wilson, JE Robertson, LM O'Rourke, JT Rosenbaum, CE Hart |
Graefe's Archive for Clinical and Experimental Ophthalmology | 1995 |
Factors involved in capillary growth in the heart
O Hudlick, MD Brown, H Walter, JB Weiss, A Bate |
Molecular and Cellular Biochemistry | 1995 |
Basic fibroblast growth factor improves myocardial function in chronically ischemic porcine hearts
K Harada, W Grossman, M Friedman, ER Edelman, PV Prasad, CS Keighley, WJ Manning, FW Sellke, M Simons |
Journal of Clinical Investigation | 1994 |
Determinants of collateral development in a canine model with repeated coronary occlusion
M Fujita, K Yamanishi, E Araie, S Sasayama, DP McKown, D Franklin |
Heart and Vessels | 1994 |
Idiopathic Dilated Cardiomyopathy
GW Dec, V Fuster |
New England Journal of Medicine | 1994 |
Basal and acidic fibroblast growth factor-induced atrial natriuretic peptide gene expression and secretion is inhibited by staurosporine
H Tokola, K Salo, O Vuolteenaho, H Ruskoaho |
European Journal of Pharmacology: Molecular Pharmacology | 1994 |
Potential effects of bradykinin on myocardial capillary growth after angiotensin converting enzyme inhibition
C Tschöpe, M Stoll, P Gohlke, T Unger |
Expert Opinion on Investigational Drugs | 1994 |
Induction of myocardial insulin-like growth factor-I gene expression in left ventricular hypertrophy
TJ Donohue, LD Dworkin, MN Lango, K Fliegner, RP Lango, JA Benstein, WR Slater, VM Catanese |
Circulation | 1994 |
Induction of acidic fibroblast growth factor and full-length platelet-derived growth factor expression in human cardiac allografts. Analysis by PCR, in situ hybridization, and immunohistochemistry
XM Zhao, TK Yeoh, WH Frist, DL Porterfield, GG Miller |
Circulation | 1994 |
Expression and subcellular distribution of basic fibroblast growth factor are regulated during migration of endothelial cells
S Biro, ZX Yu, YM Fu, G Smale, J Sasse, J Sanchez, VJ Ferrans, W Casscells |
Circulation research | 1994 |
Factors altering DNA synthesis in the cardiac myocyte of the adult newt, Notophthalmus viridescens
MH Soonpaa, JO Oberpriller, JC Oberpriller |
Cell and Tissue Research | 1994 |
Cell-cell signaling between adult rat ventricular myocytes and cardiac microvascular endothelial cells in heterotypic primary culture
M Nishida, JP Springhorn, RA Kelly, TW Smith |
Journal of Clinical Investigation | 1993 |
Purification of a basic fibroblast growth factor-binding proteoglycan from bovine cardiac plasma membrane
CR Ross, S Kubinak, CC Hale |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 1993 |
Intracoronary injection of basic fibroblast growth factor enhances angiogenesis in infarcted swine myocardium
A Battler, M Scheinowitz, A Bor, D Hasdai, Z Vered, ED Segni, N Varda-Bloom, D Nass, S Engelberg, M Eldar, M Belkin, N Savion |
Journal of the American College of Cardiology | 1993 |
Basic fibroblastic growth factor as a potential meningeal angiogenic factor
JJ Olson, A Reisner, JM Klemm, RA Bakay |
Skull base surgery | 1993 |
Cyclic Mechanical Deformation Stimulates Human Lung Fibroblast Proliferation and Autocrine Growth Factor Activity
JE Bishop, JJ Mitchell, PM Absher, L Baldor, HA Geller, J Woodcock-Mitchell, MJ Hamblin, P Vacek, RB Low |
American journal of respiratory cell and molecular biology | 1993 |
Molecular atherectomy for restenosis
W Casscells, DA Lappi, A Baird |
Trends in Cardiovascular Medicine | 1993 |
Heparin Does Not Stimulate Coronary-Collateral Growth in a Canine Model of Progressive Coronary-Artery Narrowing and Occlusion
MV Cohen, N Chukwuogo, A Yarlagadda |
The American Journal of the Medical Sciences | 1993 |
A 49-year-old woman with hypertension who deteriorates after acute myocardial infarction
W Casscells, G Schroth, LM Buja |
Circulation | 1993 |
Acidic fibroblast growth factor and heart development. Role in myocyte proliferation and capillary angiogenesis
GL Engelmann, CA Dionne, MC Jaye |
Circulation research | 1993 |
Heparin accelerates coronary collateral development in a porcine model of coronary artery occlusion
SM Carroll, FC White, DM Roth, CM Bloor |
Circulation | 1993 |
Growth Factors and the Cardiovascular System
P Cummins |
1993 | |
Augmented production of heparin-binding mitogenic proteins by preadipocytes from massively obese persons
K Teichert-Kuliszewska, BS Hamilton, M Deitel, DA Roncari |
Journal of Clinical Investigation | 1992 |
Fibroblast growth factor upregulates PGG/H synthase in rabbit microvascular endothelia cells by a glucocorticoid independent mechanism
T Moatter, ME Gerritsen |
Journal of Cellular Physiology | 1992 |
Immunolocalization of basic fibroblast growth factor to the micro vasculature of human brain tumors
S Brem, AM Tsanaclis, S Gately, JL Gross, WF Herblin |
Cancer | 1992 |
Release of cell surface-associated basic fibroblast growth factor by glycosylphosphatidylinositol-specific phospholipase C
P Bashkin, G Neufeld, H Gitay-Goren, I Vlodavsky |
Journal of Cellular Physiology | 1992 |
Enhanced angiogenesis and growth of collaterals by in vivo administration of recombinant basic fibroblast growth factor in a rabbit model of acute lower limb ischemia: Dose-response effect of basic fibroblast growth factor
R Baffour, J Berman, JL Garb, SW Rhee, J Kaufman, P Friedmann |
Journal of Vascular Surgery | 1992 |
Elimination of smooth muscle cells in experimental restenosis: targeting of fibroblast growth factor receptors
W Casscells, DA Lappi, BB Olwin, C Wai, M Siegman, EH Speir, J Sasse, A Baird |
Proceedings of the National Academy of Sciences | 1992 |
Stimulation of coronary collateral growth: Current developments in angiogenesis and future clinical applications
RW Kass, MN Kotler, S Yazdanfar |
American Heart Journal | 1992 |
Distribution of Acidic and Basic Fibroblast Growth Factors (FGF) in the Foetal Rat Eye: Implications for Lens Development
R Iongh, JW McAvoy |
Growth Factors | 1992 |
Never Ending Growth and a Growth Factor. I. Immunocytochemical Evidence for the Presence of Basic Fibroblast Growth Factor in a Tapeworm
MK Gustafsson, K Eriksson |
Growth Factors | 1992 |
Migration of smooth muscle and endothelial cells. Critical events in restenosis
W Casscells |
Circulation | 1992 |
Role of epicardial mesothelial cells in the modification of phenotype and function of adult rat ventricular myocytes in primary coculture
H Eid, DM Larson, JP Springhorn, MA Attawia, RC Nayak, TW Smith, RA Kelly |
Circulation research | 1992 |
Acidic and basic fibroblast growth factors in adult rat heart myocytes. Localization, regulation in culture, and effects on DNA synthesis
E Speir, V Tanner, AM Gonzalez, J Farris, A Baird, W Casscells |
Circulation research | 1992 |
Recent insights into coronary collateral circulation
S Sasayama, M Fujita |
Circulation | 1992 |
Chronic reduction of myocardial ischemia does not attenuate coronary collateral development in miniswine
JD Symons, KF Pitsillides, JC Longhurst |
Circulation | 1992 |
Collateral Circulation
W Schaper, J Schaper |
1992 | |
Angiogenesis in Health and Disease
ME Maragoudakis, P Gullino, PI Lelkes |
1992 | |
Cellular and Molecular Biology of Atherosclerosis
AM Gotto |
1992 | |
Cardiac Adaptation in Heart Failure
J Holtz, H Drexler, H Just |
1992 | |
Salvage of Infarcted Myocardium by Angiogenic Action of Basic Fibroblast Growth Factor
A Yanagisawa-Miwa, Y Uchida, F Nakamura, T Tomaru, H Kido, T Kamijo, T Sugimoto, K Kaji, M Utsuyama, C Kurashima, H Ito |
Science | 1992 |
Immunolocalization of basic fibroblast growth factor during chicken cardiac development
SA Consigli, J Joseph-Silverstein |
Journal of Cellular Physiology | 1991 |
Culture-induced increase in acidic and basic fibroblast growth factor activities and their association with the nuclei of vascular endothelial and smooth muscle cells
E Speir, J Sasse, S Shrivastav, W Casscells |
Journal of Cellular Physiology | 1991 |
Basic Fibroblast Growth Factor in Cultured Cardiac Myocytes
E Kardami, L Liu, BW Doble |
Annals of the New York Academy of Sciences | 1991 |
Acidic Fibroblast Growth Factor, Heart Development, and Capillary Angiogenesis
GL Engelmann, CA Dionne, MC Jaye |
Annals of the New York Academy of Sciences | 1991 |
Acidic fibroblast growth factor in the developing rat embryo
YM Fu, P Spirito, ZX Yu, S Biro, J Sasse, J Lei, VJ Ferrans, SE Epstein, W Casscells |
The Journal of Cell Biology | 1991 |
A growth factor for cardiac myocytes is produced by cardiac nonmyocytes
CS Long, CJ Henrich, PC Simpson |
Cell regulation | 1991 |
Macrophage-derived angiogenesis factors
C Sunderkötter, M Goebeler, K Schulze-Osthoff, R Bhardwaj, C Sorg |
Pharmacology & Therapeutics | 1991 |
Indirect angiogenic agents do not release fibroblast growth factors from extracellular matrix
GE Terrell, JL Swain |
Matrix | 1991 |
Distinctive patterns of basic fibroblast growth factor (bFGF) distribution in degenerating and regenerating areas of dystrophic (mdx) striated muscles
JE Anderson, L Liu, E Kardami |
Developmental Biology | 1991 |
Basic fibroblast growth factor is a substrate for phosphorylation by human neutrophil ecto-protein kinase activity
KM Skubitz, SA Goueli |
Biochemical and Biophysical Research Communications | 1991 |
Smooth muscle cell growth factors
W Casscells |
Progress in Growth Factor Research | 1991 |
Cardiac growth factors
MD Schneider, TG Parker |
Progress in Growth Factor Research | 1991 |
Amplification and sequencing of mRNA encoding acidic fibroblast growth factor (aFGF) from porcine heart
M Schmidt, HS Sharma, RJ Schott, W Schaper |
Biochemical and Biophysical Research Communications | 1991 |
Myocardial angiogenesis and coronary perfusion in left ventricular pressure-overload hypertrophy in the young lamb. Evidence for inhibition with chronic protamine administration
MF Flanagan, AM Fujii, SD Colan, RG Flanagan, JE Lock |
Circulation research | 1991 |
Immunohistochemical localization of basic and acidic fibroblast growth factors in the developing rat heart
P Spirito, YM Fu, ZX Yu, SE Epstein, W Casscells |
Circulation | 1991 |
Biochemical and ultrastructural evidence for the association of basic fibroblast growth factor with cardiac gap junctions
E Kardami, RM Stoski, BW Doble, T Yamamoto, EL Hertzberg, JI Nagy |
The Journal of biological chemistry | 1991 |
Characterization of two Preparations of Antibodies to Basic Fibroblast Growth Factor which Exhibit Distinct Patterns of Immunolocalization
E Kardami, LJ Murphy, L Liu, RR Padua, RR Fandrich |
Growth Factors | 1990 |
Autocrine regulation of cell growth and transformation by basic fibroblast growth factor
A Yayon, M Klagsbrun |
Cancer and Metastasis Reviews | 1990 |
Introduction
LD Peachey, JP Heath, KR Porter, HP Thompson, KR Porter, F Kallman |
Journal of Electron Microscopy Technique | 1987 |