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Citations to this article

Isolation, characterization, and localization of heparin-binding growth factors in the heart.
W Casscells, … , L Haggroth, J Folkman
W Casscells, … , L Haggroth, J Folkman
Published February 1, 1990
Citation Information: J Clin Invest. 1990;85(2):433-441. https://doi.org/10.1172/JCI114456.
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Isolation, characterization, and localization of heparin-binding growth factors in the heart.

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Abstract

Acidic and basic fibroblast growth factors (aFGF and bFGF) are angiogenic polypeptide mitogens for cells of mesodermal and neuroectodermal origin. In this report we describe the purification from several normal human hearts (including a very fresh, nonischemic sample) of heparin-binding, acid-, heat- and trypsin-sensitive 14-18-kD peptides that crossreact with antisera against aFGF and bFGF. Further evidence includes (a) prevention of mitogenicity by protamine and by anti-bFGF, (b) displacement of 125I-bFGF from cell membranes, and (c) stimulation of capillary endothelial cell migration. Specific immunohistochemistry localized bFGF to endothelial cells and, surprisingly, to cardiac myocytes, with almost no immunoreactivity in smooth muscle cells. These peptides may function in cardiac embryogenesis, hypertrophy, atherogenesis, angiogenesis, and wound healing, and may also have endocrine, neurotropic, or vasomotor functions.

Authors

W Casscells, E Speir, J Sasse, M Klagsbrun, P Allen, M Lee, B Calvo, M Chiba, L Haggroth, J Folkman

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Year: 2016 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1987 Total
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Role of epicardial mesothelial cells in the modification of phenotype and function of adult rat ventricular myocytes in primary coculture
H Eid, DM Larson, JP Springhorn, MA Attawia, RC Nayak, TW Smith, RA Kelly
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Acidic and basic fibroblast growth factors in adult rat heart myocytes. Localization, regulation in culture, and effects on DNA synthesis
E Speir, V Tanner, AM Gonzalez, J Farris, A Baird, W Casscells
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A Yanagisawa-Miwa, Y Uchida, F Nakamura, T Tomaru, H Kido, T Kamijo, T Sugimoto, K Kaji, M Utsuyama, C Kurashima, H Ito
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Immunolocalization of basic fibroblast growth factor during chicken cardiac development
SA Consigli, J Joseph-Silverstein
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Culture-induced increase in acidic and basic fibroblast growth factor activities and their association with the nuclei of vascular endothelial and smooth muscle cells
E Speir, J Sasse, S Shrivastav, W Casscells
Journal of Cellular Physiology 1991
Basic Fibroblast Growth Factor in Cultured Cardiac Myocytes
E Kardami, L Liu, BW Doble
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Acidic Fibroblast Growth Factor, Heart Development, and Capillary Angiogenesis
GL Engelmann, CA Dionne, MC Jaye
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Acidic fibroblast growth factor in the developing rat embryo
YM Fu, P Spirito, ZX Yu, S Biro, J Sasse, J Lei, VJ Ferrans, SE Epstein, W Casscells
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A growth factor for cardiac myocytes is produced by cardiac nonmyocytes
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Macrophage-derived angiogenesis factors
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Indirect angiogenic agents do not release fibroblast growth factors from extracellular matrix
GE Terrell, JL Swain
Matrix 1991
Distinctive patterns of basic fibroblast growth factor (bFGF) distribution in degenerating and regenerating areas of dystrophic (mdx) striated muscles
JE Anderson, L Liu, E Kardami
Developmental Biology 1991
Basic fibroblast growth factor is a substrate for phosphorylation by human neutrophil ecto-protein kinase activity
KM Skubitz, SA Goueli
Biochemical and Biophysical Research Communications 1991
Smooth muscle cell growth factors
W Casscells
Progress in Growth Factor Research 1991
Cardiac growth factors
MD Schneider, TG Parker
Progress in Growth Factor Research 1991
Amplification and sequencing of mRNA encoding acidic fibroblast growth factor (aFGF) from porcine heart
M Schmidt, HS Sharma, RJ Schott, W Schaper
Biochemical and Biophysical Research Communications 1991
Myocardial angiogenesis and coronary perfusion in left ventricular pressure-overload hypertrophy in the young lamb. Evidence for inhibition with chronic protamine administration
MF Flanagan, AM Fujii, SD Colan, RG Flanagan, JE Lock
Circulation research 1991
Immunohistochemical localization of basic and acidic fibroblast growth factors in the developing rat heart
P Spirito, YM Fu, ZX Yu, SE Epstein, W Casscells
Circulation 1991
Biochemical and ultrastructural evidence for the association of basic fibroblast growth factor with cardiac gap junctions
E Kardami, RM Stoski, BW Doble, T Yamamoto, EL Hertzberg, JI Nagy
The Journal of biological chemistry 1991
Characterization of two Preparations of Antibodies to Basic Fibroblast Growth Factor which Exhibit Distinct Patterns of Immunolocalization
E Kardami, LJ Murphy, L Liu, RR Padua, RR Fandrich
Growth Factors 1990
Autocrine regulation of cell growth and transformation by basic fibroblast growth factor
A Yayon, M Klagsbrun
Cancer and Metastasis Reviews 1990
Introduction
LD Peachey, JP Heath, KR Porter, HP Thompson, KR Porter, F Kallman
Journal of Electron Microscopy Technique 1987

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