Plasmodium falciparum-infected erythrocytes (IE) specifically adhere to vascular endothelium in vivo and to human endothelial cells, some human melanoma cell lines, and human monocytes in vitro. The tissue cell receptor for a ligand on the surface of the infected erythrocytes is an Mr 88,000 glycoprotein (GP88) recognized by the MAb OKM5, which also blocks cytoadherence of IE. Isolated, affinity-purified GP88 (CD36) competitively blocks cytoadherence and when absorbed to plastic surfaces, specifically binds P. falciparum IE. Additionally, monoclonal and polyclonal antibodies to GP88 block cytoadherence to both target cells and immobilized GP88. Binding to GP88 by IE is unaffected by the absence of calcium or the absence of thrombospondin, a putative mediator for cytoadherence of P. falciparum IE. Thus, GP88 (CD36), which has been demonstrated to be the same as platelet glycoprotein IV, interacts directly with P. falciparum IE, presumably via a parasite-induced ligand exposed on the surface of the infected erythrocytes. CD36 is shown to be present on brain endothelium in both individuals without malaria and individuals with cerebral malaria. This would suggest that factors other than just cerebral sequestration of IE play an initiating role in the genesis of cerebral malaria.
J W Barnwell, A S Asch, R L Nachman, M Yamaya, M Aikawa, P Ingravallo
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AM Vogt, F Pettersson, K Moll, C Jonsson, J Normark, U Ribacke, TG Egwang, HP Ekre, D Spillmann, Q Chen, M Wahlgren, JC Boothroyd |
PLoS pathogens | 2006 |
Levels of Plasma Immunoglobulin G with Specificity against the Cysteine-Rich Interdomain Regions of a Semiconserved Plasmodium falciparum Erythrocyte Membrane Protein 1, VAR4, Predict Protection against Malarial Anemia and Febrile Episodes
JP Lusingu, AT Jensen, LS Vestergaard, DT Minja, MB Dalgaard, S Gesase, BP Mmbando, AY Kitua, MM Lemnge, D Cavanagh, L Hviid, TG Theander |
Infection and immunity | 2006 |
How Malaria Has Affected the Human Genome and What Human Genetics Can Teach Us about Malaria
DP Kwiatkowski |
The American Journal of Human Genetics | 2005 |
Identifying Plasmodium falciparum cytoadherence-linked asexual protein 3 (CLAG 3) sequences that specifically bind to C32 cells and erythrocytes
M Ocampo, LE Rodríguez, H Curtidor, A Puentes, R Vera, JJ Valbuena, R López, JE García, LE Ramírez, E Torres, J Cortes, D Tovar, Y López, MA Patarroyo, ME Patarroyo |
Protein science : a publication of the Protein Society | 2005 |
Carrageenans inhibit the in vitro growth of Plasmodium falciparum and cytoadhesion to CD36
Y Adams, SL Smith, R Schwartz-Albiez, KT Andrews |
Parasitology Research | 2005 |
The role of ICAM-1 in Plasmodium falciparum cytoadherence
SJ Chakravorty, A Craig |
European Journal of Cell Biology | 2005 |
Plasmodium falciparum malaria in south-west Nigerian children: Is the polymorphism of ICAM-1 and E-selectin genes contributing to the clinical severity of malaria?
OK Amodu, RA Gbadegesin, SA Ralph, AA Adeyemo, PE Brenchley, OO Ayoola, AE Orimadegun, AK Akinsola, PE Olumese, OO Omotade |
Acta Tropica | 2005 |
The Blood-Brain Barrier and Its Microenvironment: Basic Physiology to Neurological Disease
H Wolburg, A Warth |
The Blood-Brain Barrier and Its Microenvironment: Basic Physiology to Neurological Disease | 2005 |
Clinical and molecular aspects of severe malaria
K Kirchgatter, HA Portillo |
Anais da Academia Brasileira de Ciências | 2005 |
Direct Activation of Human Endothelial Cells by Plasmodium falciparum -Infected Erythrocytes
NK Viebig, U Wulbrand, R Förster, KT Andrews, M Lanzer, PA Knolle |
Infection and immunity | 2005 |
Molecular Approaches to Malaria
IW Sherman |
2005 | |
Immunohistological study on bovine, swine and ovine skeletal muscle fibers for the localization of fatty acid translocase FAT/CD36
T BANDA, D NEUPANEY, J KIM, M ISHIOROSHI, K MARUKAWA, H CHIBA, T ITO, K SAMEJIMA |
Animal Science Journal | 2004 |
Gametocytogenesis: the puberty of Plasmodium falciparum
AM Talman, O Domarle, FE McKenzie, F Ariey, V Robert |
Malaria Journal | 2004 |
Functional interdependence of the DBLβ domain and c2 region for binding of the Plasmodium falciparum variant antigen to ICAM-1
AL Springer, LM Smith, DQ Mackay, SO Nelson, JD Smith |
Molecular and Biochemical Parasitology | 2004 |
Chemical modifications of band 3 protein affect the adhesion of Plasmodium falciparum-infected erythrocytes to CD36
E Winograd, S Eda, IW Sherman |
Molecular and Biochemical Parasitology | 2004 |
Clinical features and pathogenesis of severe malaria
CL Mackintosh, JG Beeson, K Marsh |
Trends in Parasitology | 2004 |
Src-family kinase signaling modulates the adhesion ofPlasmodium falciparum on human microvascular endothelium under flow
BG Yipp, SM Robbins, ME Resek, DI Baruch, S Looareesuwan, M Ho |
Blood | 2003 |
Plasmodium coatneyi-Infected Erythrocytes Bind to C32 Amelanotic Melanoma Cells under Static and Flow Conditions
S KAWAI, M YOSHINARI, J MATSUMOTO, M KIRINOKI, M AIKAWA, M MINAMI, H MATSUDA |
Journal of Veterinary Medical Science | 2003 |
Sub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regions
T Lavstsen, A Salanti, AT Jensen, DE Arnot, TG Theander |
Malaria Journal | 2003 |
ICAM-1 can play a major role in mediating P. falciparum adhesion to endothelium under flow
C Gray, C McCormick, G Turner, A Craig |
Molecular and Biochemical Parasitology | 2003 |
Divergent binding sites on intercellular adhesion molecule-1 (ICAM-1) for variant Plasmodium falciparum isolates
MT Tse, K Chakrabarti, C Gray, CE Chitnis, A Craig |
Molecular Microbiology | 2003 |
Heparan sulfate on endothelial cells mediates the binding ofPlasmodium falciparum–infected erythrocytes via the DBL1α domain of PfEMP1
AM Vogt, A Barragan, Q Chen, F Kironde, D Spillmann, M Wahlgren |
Blood | 2003 |
Malarial Nephropathy
S Eiam-Ong |
Seminars in Nephrology | 2003 |
Plasmodium yoelii Sporozoites Infect CD36-Deficient Mice
P Sinnis, M Febbraio |
Experimental Parasitology | 2002 |
CD36, a Class B Scavenger Receptor, Is Expressed on Microglia in Alzheimer's Disease Brains and Can Mediate Production of Reactive Oxygen Species in Response to β-Amyloid Fibrils
IS Coraci, J Husemann, JW Berman, C Hulette, JH Dufour, GK Campanella, AD Luster, SC Silverstein, JB el Khoury |
The American Journal of Pathology | 2002 |
Febrile temperatures induce cytoadherence of ring-stage Plasmodium falciparum-infected erythrocytes
R Udomsangpetch, B Pipitaporn, K Silamut, R Pinches, S Kyes, S Looareesuwan, C Newbold, NJ White |
Proceedings of the National Academy of Sciences | 2002 |
Immunization of Aotus monkeys with a functional domain of the Plasmodium falciparum variant antigen induces protection against a lethal parasite line
DI Baruch, B Gamain, JW Barnwell, JA Sullivan, A Stowers, GG Galland, LH Miller, WE Collins |
Proceedings of the National Academy of Sciences | 2002 |
CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils
IS Coraci, J Husemann, JW Berman, C Hulette, JH Dufour, GK Campanella, AD Luster, SC Silverstein, JB El-Khoury |
The American Journal of Pathology | 2002 |
Scavenger receptors in neurobiology and neuropathology: Their role on microglia and other cells of the nervous system
J Husemann, JD Loike, R Anankov, M Febbraio, SC Silverstein |
Glia | 2002 |
Malaria pathogenesis: a jigsaw with an increasing number of pieces
A Heddini |
International Journal for Parasitology | 2002 |
Evaluating specific adhesion of Plasmodium falciparum-infected erythrocytes to immobilised hyaluronic acid with comparison to binding of mammalian cells
JG Beeson, SJ Rogerson, GV Brown |
International Journal for Parasitology | 2002 |
Impaired Macrophage Responses May Contribute to Exacerbation of Blood-StagePlasmodium chabaudi chabaudiMalaria in Interleukin-12-Deficient Mice
KR Bastos, R Barboza, RM Elias, LR Sardinha, MG Grisotto, CR Marinho, GP Amarante-Mendes, JM Alvarez, MR Lima |
Journal of Interferon & Cytokine Research | 2002 |
Methods in Cell Biology
JW Smith |
Methods in cell biology | 2002 |
Impaired Macrophage Responses May Contribute to Exacerbation of Blood-Stage Plasmodium chabaudi chabaudi Malaria in Interleukin-12-Deficient Mice
KR Bastos, R Barboza, RM Elias, LR Sardinha, MG Grisotto, CR Marinho, GP Amarante-Mendes, JM Alvarez, MR Lima |
Journal of Interferon & Cytokine Research | 2002 |
Nitric Oxide and Infection
FC Fang |
2002 | |
Malaria-Induced Acquisition of Antibodies to Plasmodium falciparum Variant Surface Antigens
MF Ofori, D Dodoo, T Staalsoe, JA Kurtzhals, K Koram, TG Theander, BD Akanmori, L Hviid |
Infection and immunity | 2002 |
A role for CD36 in the regulation of dendritic cell function
BC Urban, N Willcox, DJ Roberts |
Proceedings of the National Academy of Sciences | 2001 |
Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria
A Pain, DJ Ferguson, O Kai, BC Urban, B Lowe, K Marsh, DJ Roberts |
Proceedings of the National Academy of Sciences | 2001 |
ANTIGENICVARIATION AT THEINFECTEDREDCELLSURFACE INMALARIA
S Kyes, P Horrocks, C Newbold |
Annual Review of Microbiology | 2001 |
Epitopes for modified band 3 monoclonal antibody 1C4 are not exposed on the malaria-infected red blood cell surface
RE Hayward, KP Day |
Molecular and Biochemical Parasitology | 2001 |
Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar β-amyloid
J Husemann, JD Loike, T Kodama, SC Silverstein |
Journal of Neuroimmunology | 2001 |
Association of adhesion molecule PECAM-1/CD31 polymorphism with susceptibility to cerebral malaria in Thais
M Kikuchi, S Looareesuwan, R Ubalee, O Tasanor, F Suzuki, Y Wattanagoon, K Na-Bangchang, A Kimura, M Aikawa, K Hirayama |
Parasitology International | 2001 |
Fresh Isolates from Children with Severe Plasmodium falciparum Malaria Bind to Multiple Receptors
WA Petri, A Heddini, F Pettersson, O Kai, J Shafi, J Obiero, Q Chen, A Barragan, M Wahlgren, K Marsh |
Infection and immunity | 2001 |
Modifications in the CD36 binding domain of the Plasmodium falciparum variant antigen are responsible for the inability of chondroitin sulfate A adherent parasites to bind CD36
B Gamain, JD Smith, LH Miller, DI Baruch |
Blood | 2001 |
Molecular aspects of severe malaria
Q Chen, M Schlichtherle, M Wahlgren |
Clinical microbiology reviews | 2000 |
clag9: A cytoadherence gene in Plasmodium falciparum essential for binding of parasitized erythrocytes to CD36
KR Trenholme, DL Gardiner, DC Holt, EA Thomas, AF Cowman, DJ Kemp |
Proceedings of the National Academy of Sciences | 2000 |
Identification of a Plasmodium falciparum intercellular adhesion molecule-1 binding domain: a parasite adhesion trait implicated in cerebral malaria
JD Smith, AG Craig, N Kriek, D Hudson-Taylor, S Kyes, T Fagan, T Fagen, R Pinches, DI Baruch, CI Newbold, LH Miller |
Proceedings of the National Academy of Sciences | 2000 |
Cerebral malaria and immunogenetics
D Mazier, J Nitcheu, M Idrissa-Boubou |
Parasite Immunology | 2000 |
The ves Multigene Family of B. bovis Encodes Components of Rapid Antigenic Variation at the Infected Erythrocyte Surface
DR Allred, JM Carlton, RL Satcher, JA Long, WC Brown, PE Patterson, RM O'Connor, SE Stroup |
Molecular Cell | 2000 |
Assessing the impact of Plasmodium falciparum genome sequencing
S Bowman, P Horrocks |
Microbes and Infection | 2000 |
Severe falciparum malaria
WH Organization |
Transactions of the Royal Society of Tropical Medicine and Hygiene | 2000 |
Haptoglobin 1-1 is associated with susceptibility to severe Plasmodium falciparum malaria
IK Quaye, FA Ekuban, BQ Goka, V Adabayeri, JA Kurtzhals, B Gyan, NA Ankrah, L Hviid, BD Akanmori |
Transactions of the Royal Society of Tropical Medicine and Hygiene | 2000 |
Identification of a Plasmodium falciparum intercellular adhesion molecule-1 binding domain: A parasite adhesion trait implicated in cerebral malaria
JD Smith, AG Craig, N Kriek, D Hudson-Taylor, S Kyes, T Fagan, R Pinches, DI Baruch, CI Newbold, LH Miller |
Proceedings of the National Academy of Sciences | 2000 |
The Semiconserved Head Structure of Plasmodium falciparum Erythrocyte Membrane Protein 1 Mediates Binding to Multiple Independent Host Receptors
Q Chen, A Heddini, A Barragan, V Fernandez, SF Pearce, M Wahlgren |
Journal of Experimental Medicine | 2000 |
Characterization of Proteoglycans of Human Placenta and Identification of Unique Chondroitin Sulfate Proteoglycans of the Intervillous Spaces That Mediate the Adherence of Plasmodium falciparum -infected Erythrocytes to the Placenta
RN Achur, M Valiyaveettil, A Alkhalil, CF Ockenhouse, DC Gowda |
The Journal of biological chemistry | 2000 |
Plasma Antibodies from Malaria-Exposed Pregnant Women Recognize Variant Surface Antigens on Plasmodium falciparum -Infected Erythrocytes in a Parity-Dependent Manner and Block Parasite Adhesion to Chondroitin Sulfate A
CH Ricke, T Staalsoe, K Koram, BD Akanmori, EM Riley, TG Theander, L Hviid |
Journal of immunology (Baltimore, Md. : 1950) | 2000 |
Dermal Microvascular Endothelial Cells Express the 180-kDa Macrophage Mannose Receptor In Situ and In Vitro
M Gröger, W Holnthoner, D Maurer, S Lechleitner, K Wolff, BB Mayr, W Lubitz, P Petzelbauer |
Journal of immunology (Baltimore, Md. : 1950) | 2000 |
Sulfated glycoconjugates enhance CD36-dependent adhesion ofPlasmodium falciparum–infected erythrocytes to human microvascular endothelial cells
CJ McCormick, CI Newbold, AR Berendt |
Blood | 2000 |
Differential Binding of Clonal Variants of Plasmodium falciparum to Allelic Forms of Intracellular Adhesion Molecule 1 Determined by Flow Adhesion Assay
JM Mansfield, S Adams, GD Turner, GB Nash, K Micklem, CI Newbold, AG Craig |
Infection and immunity | 2000 |
Plasmodium chabaudi -Infected Erythrocytes Adhere to CD36 and Bind to Microvascular Endothelial Cells in an Organ-Specific Way
JM Mansfield, MM Mota, W Jarra, E Hirst, PK Patnaik, AA Holder |
Infection and immunity | 2000 |
Plasmodium falciparum isolates from infected pregnant women and children are associated with distinct adhesive and antigenic properties
JG Beeson, GV Brown, ME Molyneux, C Mhango, F Dzinjalamala, SJ Rogerson |
The Journal of Infectious Diseases | 1999 |
The adhesion of Plasmodium falciparum-infected erythrocytes to chondroitin sulfate A is mediated by P. falciparum erythrocyte membrane protein 1
JC Reeder, AF Cowman, KM Davern, JG Beeson, JK Thompson, SJ Rogerson, GV Brown |
Proceedings of the National Academy of Sciences | 1999 |
Plasmodium falciparum-infected erythrocyte adhesion to the type 3 repeat domain of thrombospondin-1 is mediated by a modified band 3 protein
S Eda, J Lawler, IW Sherman |
Molecular and Biochemical Parasitology | 1999 |
Cytoadherence, pathogenesis and the infected red cell surface in Plasmodium falciparum
C Newbold, A Craig, S Kyes, A Rowe, D Fernandez-Reyes, T Fagan |
International Journal for Parasitology | 1999 |
T cell response in malaria pathogenesis: selective increase in T cells carrying the TCR V 8 during experimental cerebral malaria
MI Boubou, A Collette, D Voegtle, D Mazier, PA Cazenave, S Pied |
International Immunology | 1999 |
Plasmodium falciparum: Pathogenesis, polymorphism and the infected red cell surface
C Newbold, A Craig, S Kyes, A Rowe, D Fernandez-Reyes, T Fagan |
Transfusion Clinique et Biologique | 1999 |
Molecular mechanisms of cytoadherence in malaria
M Ho, NJ White |
American journal of physiology. Cell physiology | 1999 |
CD36, a Novel Receptor for Oxidized Low-Density Lipoproteins, Is Highly Expressed on Lipid-Laden Macrophages in Human Atherosclerotic Aorta
A Nakata, Y Nakagawa, M Nishida, S Nozaki, J Miyagawa, T Nakagawa, R Tamura, K Matsumoto, K Kameda-Takemura, S Yamashita, Y Matsuzawa |
Arteriosclerosis, thrombosis, and vascular biology | 1999 |
Plasmodium falciparum-infected erythrocytes modulate the maturation of dendritic cells
BC Urban, DJ Ferguson, A Pain, N Willcox, M Plebanski, JM Austyn, DJ Roberts |
Nature | 1999 |
Cell adhesion molecules in the pathogenesis of and host defence against microbial infection
JR Kerr |
Molecular Pathology | 1999 |
The biology of Plasmodium falciparum transmission stages
KP Day, RE Hayward, M Dyer |
Parasitology | 1998 |
CD36 is rapidly and transiently upregulated on phytohemagglutinin (PHA)-stimulated peripheral blood lymphocytes. Analysis by a new monoclonal antibody (UN7)
P Tassone, F Tuccillo, P Bonelli, MC Turco, L Cecco, M Cerra, HM Bond, V Barbieri, S Venuta |
Tissue Antigens | 1998 |
Inhibition of binding of malaria-infected erythrocytes by a tetradecasaccharide fraction from chondroitin sulfate A
JG Beeson, W Chai, SJ Rogerson, AM Lawson, GV Brown |
Infection and immunity | 1998 |
CD36-dependent adhesion and knob expression of the transmission stages of Plasmodium falciparum is stage-specific
KP Day, RE Hayward, D Smith, JG Culvenor |
Molecular and Biochemical Parasitology | 1998 |
Analysis of adhesive domains from the A4VAR Plasmodium falciparum erythrocyte membrane protein-1 identifies a CD36 binding domain
JD Smith, S Kyes, AG Craig, T Fagan, D Hudson-Taylor, LH Miller, DI Baruch, CI Newbold |
Molecular and Biochemical Parasitology | 1998 |
The role of rosetting in the multiplication of Plasmodium falciparum: rosette formation neither enhances nor targets parasite invasion into uninfected red cells
B Clough, FA Atilola, G Pasvol |
British Journal of Haematology | 1998 |
Molecular basis for evasion of host immunity and pathogenesis in malaria
R Ramasamy |
Biochimica et Biophysica Acta | 1998 |
Oxidized LDL Increases and Interferon-γ Decreases Expression of CD36 in Human Monocyte–Derived Macrophages
T Nakagawa, S Nozaki, M Nishida, JM Yakub, Y Tomiyama, A Nakata, K Matsumoto, T Funahashi, K Kameda-Takemura, Y Kurata, S Yamashita, Y Matsuzawa |
Arteriosclerosis, thrombosis, and vascular biology | 1998 |
The Plasmodium falciparum–CD36 Interaction Is Modified by a Single Amino Acid Substitution in CD36
L Serghides, I Crandall, E Hull, KC Kain |
Blood | 1998 |
Biological and Biochemical Characteristics of Cytoadhesion of Plasmodium falciparum -Infected Erythrocytes to Chondroitin-4-Sulfate
JM Mansfield, B Pouvelle, T Fusaï, C Lépolard, J Gysin |
Infection and immunity | 1998 |
Multiple Adhesive Phenotypes Linked to Rosetting Binding of Erythrocytes in Plasmodium falciparum Malaria
V Fernandez, CJ Treutiger, GB Nash, M Wahlgren |
Infection and immunity | 1998 |
Intercellular adhesion molecule-1 and CD36 synergize to mediate adherence of Plasmodium falciparum-infected erythrocytes to cultured human microvascular endothelial cells
CJ McCormick, A Craig, D Roberts, CI Newbold, AR Berendt |
Journal of Clinical Investigation | 1997 |
Characterization of Two Vaccinia CD36 Recombinant-Virus-Generated Monoclonal Antibodies (10/5, 13/10). Effects on Malarial cytoadherence and Platelet Functions
L Daviet, AG Craig, L Mcgregor, R Pinches, TF Wild, AR Berendt, CI Newbold, JL Mcgregor |
European Journal of Biochemistry | 1997 |
Failure to block adhesion of Plasmodium falciparum-infected erythrocytes to ICAM-1 with soluble ICAM-1
AG Craig, R Pinches, S Khan, DJ Roberts, GD Turner, CI Newbold, AR Berendt |
Infection and immunity | 1997 |
The chromosomal organization of the Plasmodium falciparum var gene family is conserved
JK Thompson, JP Rubio, S Caruana, A Brockman, ME Wickham, AF Cowman |
Molecular and Biochemical Parasitology | 1997 |
ImagingPlasmodium falciparum-Infected Ghost and Parasite by Atomic Force Microscopy
CR Garcia, M Takeuschi, K Yoshioka, H Miyamoto |
Journal of Structural Biology | 1997 |
Cerebral Malaria
G Turner |
Brain Pathology | 1997 |
Plasmodium fragile:Efficacy of Arteether (α/β) against Cerebral Malaria Model
R Tripathi, RA Vishwakarma, GP Dutta |
Experimental Parasitology | 1997 |
Targeted Gene Disruption Shows That Knobs Enable Malaria-Infected Red Cells to Cytoadhere under Physiological Shear Stress
BS Crabb, BM Cooke, JC Reeder, RF Waller, SR Caruana, KM Davern, ME Wickham, GV Brown, RL Coppel, AF Cowman |
Cell | 1997 |
PfEMP1, polymorphism and pathogenesis
CI Newbold, AG Craig, S Kyes, AR Berendt, RW Snow, N Peshu, K Marsh |
Annals of Tropical Medicine and Parasitology | 1997 |
Host—parasite interaction and morbidity in malaria endemic areas
FY Liew, K Vickerman, K Marsh, RW Snow |
Philosophical Transactions of The Royal Society B Biological Sciences | 1997 |
Identification of a Region of PfEMP1 That Mediates Adherence of Plasmodium falciparum Infected Erythrocytes to CD36: Conserved Function With Variant Sequence
DI Baruch, XC Ma, HB Singh, X Bi, BL Pasloske, RJ Howard |
Blood | 1997 |
Cerebral malaria.
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Brain Pathology | 1997 |
Functional roles of membrane glycoprotein CD36
L Daviet, JL McGregor |
Platelets | 1996 |
Variant antigens and endothelial receptor adhesion in Plasmodium falciparum
JP Gardner, RA Pinches, DJ Roberts, CI Newbold |
Proceedings of the National Academy of Sciences | 1996 |
CD36 and intercellular adhesion molecule 1 mediate adhesion of developing Plasmodium falciparum gametocytes
NJ Rogers, O Daramola, GA Targett, BS Hall |
Infection and immunity | 1996 |
Plasmodium falciparum gametocyte adhesion to C32 cells via CD36 is inhibited by antibodies to modified band 3
NJ Rogers, GA Targett, BS Hall |
Infection and immunity | 1996 |
Plasmodium falciparum erythrocyte membrane protein 1 is a parasitized erythrocyte receptor for adherence to CD36, thrombospondin, and intercellular adhesion molecule 1
DI Baruch, JA Gormely, C Ma, RJ Howard, BL Pasloske |
Proceedings of the National Academy of Sciences | 1996 |
Release of malaria circumsporozoite protein into the host cell cytoplasm and interaction with ribosomes
FU Hügel, G Pradel, U Frevert |
Molecular and Biochemical Parasitology | 1996 |
Antigenic variation and immune evasion in Plasmodium falciparum malaria
JC Reeder, GV Brown |
Immunology and Cell Biology | 1996 |
Novel fibrillar structure confers adhesive property to malaria–infected erythrocytes
C Scholander, CJ Treutiger, K Hultenby, M Wahlgren |
Nature Medicine | 1996 |
The human anion transport protein, band 3, contains a CD36-like binding domain for Plasmodium falciparum-infected erythrocytes
I Crandall, IW Sherman |
Parasitology | 1996 |
To tell the truth: Will the real CD36 please stand up?
A Asch |
Journal of Laboratory and Clinical Medicine | 1996 |
Primary culture of human lung microvessel endothelial cells : A useful in vitro model for studying Plasmodium falciparum-infected erythrocyte cytoadherence
K Muanza, F Gay, C Behr, A Scherf |
Research in Immunology | 1996 |
CD36 participates in the phagocytosis of rod outer segments by retinal pigment epithelium
SW Ryeom, JR Sparrow, RL Silverstein |
Journal of cell science | 1996 |
Cytoadhesion and Falciparum Malaria: Going with the flow
BM Cooke, RL Coppel |
Parasitology Today | 1995 |
Identification of a Functional Site on CD36 Involved in the Interaction Between Platelets and Collagen
N Mercier, B Catimel, MP Reck, D Pellecchia, JL McGregor |
Platelets | 1995 |
Listeria monocytogenes infects human endothelial cells by two distinct mechanisms
DA Drevets, RT Sawyer, TA Potter, PA Campbell |
Infection and immunity | 1995 |
Detection of a LFA-1-like epitope on the surface of erythrocytes infected with a strain of Plasmodium falciparum
F Tacchini-Cottier, JN Lou, DJ Roberts, AM Garcia, GE Grau |
Immunology | 1995 |
Molecular cloning of a gene from Plasmodium falciparum that codes for a protein sharing motifs found in adhesive molecules from mammals and Plasmodia
F Trottein, T Triglia, AF Cowman |
Molecular and Biochemical Parasitology | 1995 |
Switches in expression of plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes
JD Smith, CE Chitnis, AG Craig, DJ Roberts, DE Hudson-Taylor, DS Peterson, R Pinches, CI Newbold, LH Miller |
Cell | 1995 |
Isolation and characterization of brain microvascular endothelial cells from Saimiri monkeys An in vitro model for sequestration of Plasmodium falciparum-infected erythrocytes
F Gay, C Robert, B Pouvelle, S Peyrol, A Scherf, J Gysin |
Journal of Immunological Methods | 1995 |
Anti-adhesive antibodies and peptides as potential therapeutics for Plasmodium falciparum malaria
KM Land, IW Sherman, J Gysin, IE Crandall |
Parasitology Today | 1995 |
Immune Evasion by Babesia bovis and Plasmodium falciparum: Cliff-dwellers of the Parasite World
DR Allred |
Parasitology Today | 1995 |
Chondroitin-4-sulphate (proteoglycan) a receptor for Plasmodium falciparum-infected erythrocyte adherence on brain microvascular endothelial cells
C Robert, B Pouvelle, P Meyer, K Muanza, H Fujioka, M Aikawa, A Scherf, J Gysin |
Research in Immunology | 1995 |
Switches in Expression of Plasmodium falciparum var Genes Correlate with Changes in Antigenic and Cytoadherent Phenotypes of Infected Erythrocytes
JD Smith, CE Chitnis, AG Craig, DJ Roberts, DE Hudson-Taylor, DS Peterson, R Pinches, CI Newbold, LH Miller |
Cell | 1995 |
MALARIA, THE RED CELL, AND THE ENDOTHELIUM
BL Ph.D, RJ Ph.D |
Annual Review of Medicine | 1994 |
Vascular Endothelium
MA Gimbrone, MI Cybulsky, N Kume, T Collins, N Resnick |
Annals of the New York Academy of Sciences | 1994 |
An immunohistochemical study of the pathology of fatal malaria. Evidence for widespread endothelial activation and a potential role for intercellular adhesion molecule-1 in cerebral sequestration
GD Turner, H Morrison, M Jones, TM Davis, S Looareesuwan, ID Buley, KC Gatter, CI Newbold, S Pukritayakamee, B Nagachinta |
The American Journal of Pathology | 1994 |
Multiple ligands for cytoadherence can be present simultaneously on the surface of Plasmodium falciparum-infected erythrocytes
SC Chaiyaroj, RL Coppel, S Novakovic, GV Brown |
Proceedings of the National Academy of Sciences | 1994 |
Characterization of trafficking pathways and membrane genesis in malaria-infected erythrocytes
B Pouvelle, JA Gormley, TF Taraschi |
Molecular and Biochemical Parasitology | 1994 |
A Plasmodium falciparum isolate with a chromosome 9 deletion expresses a trypsin-resistant cytoadherence molecule
SC Chaiyaroj, RL Coppel, C Magowan, GV Brown |
Molecular and Biochemical Parasitology | 1994 |
Rolling and stationary cytoadhesion of red blood cells parasitized by Plasmodium falciparum: separate roles for ICAM-1, CD36 and thrombospondin
BM Cooke, AR Berendt, AG Craig, J MacGregor, CI Newbold, GB Nash |
British Journal of Haematology | 1994 |
Molecular mechanisms of sequestration in malaria
AR Berendt, DJ Ferguson, J Gardner, G Turner, A Rowe, C McCormick, D Roberts, A Craig, R Pinches, BC Elford, CI Newbold |
Parasitology | 1994 |
Rosetting
M Wahlgren, V Fernandez, C Scholander, J Carlson |
Parasitology Today | 1994 |
Platelet activation results in a redistribution of glycoprotein IV (CD36)
AD Michelson, JD Wencel-Drake, AS Kestin, MR Barnard |
Arteriosclerosis Thrombosis and Vascular Biology | 1994 |
Tropical respiratory medicine. 4. Acute tropical infections and the lung
S Johnson, R Wilkinson, RN Davidson |
Thorax | 1994 |
Parasite virulence factors during falciparum malaria: rosetting, cytoadherence, and modulation of cytoadherence by cytokines
P Ringwald, F Peyron, JP Lepers, P Rabarison, C Rakotomalala, M Razanamparany, M Rabodonirina, J Roux, JL Bras |
Infection and immunity | 1993 |
Antigenic and functional differences in adhesion of Plasmodium falciparum-infected erythrocytes to human and bovine CD36
CF Ockenhouse, NN Tandon, GA Jamieson, DE Greenwalt |
Infection and immunity | 1993 |
Cloning and characterization of a Plasmodium falciparum gene encoding a novel high-molecular weight host membrane-associated protein, PfEMP3
BL Pasloske, DI Baruch, MR van Schravendlijk, SM Handunnetti, M Aikawa, H Fujioka, TF Taraschi, JA Gormley, RJ Howard |
Molecular and Biochemical Parasitology | 1993 |
Adhesion of parasitized red blood cells to cultured endothelial cells: a flow-based study of isolates from Gambian children with falciparum malaria
BM Cooke, S Morris-Jones, BM Greenwood, GB Nash |
Parasitology | 1993 |
Sequestration and its discontents: infected erythrocyte-endothelial cell interactions in Plasmodium falciparum malaria
AR Berendt |
Research in Immunology | 1993 |
Peptides 1992
CH Schneider, AN Eberle |
1993 | |
Analysis of CD36 Binding Domains: Ligand Specificity Controlled by Dephosphorylation of an Ectodomain
AS Asch, I Liu, FM Briccetti, JW Barnwell, F Kwakye-Berko, A Dokun, J Goldberger, M Pernambuco |
Science | 1993 |
Plasmodium falciparum: diversity of isolates from Malawi in their cytoadherence to melanoma cells and monocytes in vitro
JD Goldring, ME Molyneux, T Taylor, J Wirima, M Hommel |
British Journal of Haematology | 1992 |
Normal aggregations of glycoprotein IV (CD36)-deficient platelets from seven healthy Japanese donors
N Yamamoto, N Akamatsu, H Yamazaki, K Tanoue |
British Journal of Haematology | 1992 |
Epitopic Heterogeneity of the CD36 Antigen Expressed by Normal and Neoplastic Endothelial Cells: An Immunohistochemical Study with a Novel Monoclonal Antibody 8C9
E Kudo, T Hirose, T Sano, K Hizawa |
Pathology International | 1992 |
Plasmodium falciparum-infected erythrocytes bind ICAM-1 at a site distinct from LFA-1, Mac-1, and human rhinovirus
CF Ockenhouse, R Betageri, TA Springer, DE Staunton |
Cell | 1992 |
Cytoadherence characteristics of rosette-forming Plasmodium falciparum
R Udomsangpetch, HK Webster, K Pattanapanyasat, S Pitchayangkul, S Thaithong |
Infection and immunity | 1992 |
Human platelet glycoprotein IIIb binds to thrombospondin fragments bearing the C-terminal region, and/or the type I repeats (CSVTCG motif), but not to the N-terminal heparin-binding region
B Catimel, L Leung, H Ghissasi, N Mercier, J McGregor |
Biochemical Journal | 1992 |
Blood-brain barrier and new approaches to brain drug delivery
WM Pardridge, RJ Boado, KL Black, PA Cancilla |
The Western journal of medicine | 1992 |
Trafficking of malarial proteins to the host cell cytoplasm and erythrocyte surface membrane involves multiple pathways
JA Gormley, RJ Howard, TF Taraschi |
The Journal of Cell Biology | 1992 |
Human vascular endothelial cell adhesion receptors for Plasmodium falciparum-infected erythrocytes: roles for endothelial leukocyte adhesion molecule 1 and vascular cell adhesion molecule 1
CF Ockenhouse, T Tegoshi, Y Maeno, C Benjamin, M Ho, KE Kan, Y Thway, K Win, M Aikawa, RR Lobb |
Journal of Experimental Medicine | 1992 |
Plasmodium falciparum-infected erythrocytes do not adhere well to C32 melanoma cells or CD36 unless rosettes with uninfected erythrocytes are first disrupted
SM Handunnetti, TH Hasler, RJ Howard |
Infection and immunity | 1992 |
Thrombospondin sequence motif (CSVTCG) is responsible for CD36 binding
AS Asch, S Silbiger, E Heimer, RL Nachman |
Biochemical and Biophysical Research Communications | 1992 |
The binding site on ICAM-1 for plasmodium falciparum-infected erythrocytes overlaps, but is distinct from, the LFA-1-binding site
AR Berendt, A McDowall, AG Craig, PA Bates, MJ Sternberg, K Marsh, CI Newbold, N Hogg |
Cell | 1992 |
Malaria-a neglected disease?
K Marsh |
Parasitology | 1992 |
Plasmodium falciparum: Cytoadherence of malaria-infected erythrocytes to human brain capillary and umbilical vein endothelial cells—A comparative study of adhesive ligands
H Smith, JA Nelson, CG Gahmberg, I Crandall, IW Sherman |
Experimental Parasitology | 1992 |
Rapid switching to multiple antigenic and adhesive phenotypes in malaria
DJ Roberts, Craig, AR Berendt, R Pinches, G Nash, K Marsh, CI Newbold |
Nature | 1992 |
Asexual deviants take over
RJ Howard |
Nature | 1992 |
Sense and antisense cDNA transfection of CD36 (glycoprotein IV) in melanoma cells. Role of CD36 as a thrombospondin receptor
RL Silverstein, M Baird, SK Lo, LM Yesner |
The Journal of biological chemistry | 1992 |
CD36 peptides enhance or inhibit CD36-thrombospondin binding. A two-step process of ligand-receptor interaction
LL Leung, WX Li, JL McGregor, G Albrecht, RJ Howard |
The Journal of biological chemistry | 1992 |
Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human platelets
MM Huang, JB Bolen, JW Barnwell, SJ Shattil, JS Brugge |
Proceedings of the National Academy of Sciences | 1991 |
Separation of important new platelet glycoproteins (GPIa, GPIc, GPIc*, GPIIa and GMP-140) by f.p.l.c. Characterization by monoclonal antibodies and gas-phase sequencing
B Catimel, S Parmentier, LL Leung, JL McGregor |
Biochemical Journal | 1991 |
Clinical correlates of in vitro Plasmodium falciparum cytoadherence
M Ho, B Singh, S Looareesuwan, TM Davis, D Bunnag, NJ White |
Infection and immunity | 1991 |
Sequestrin, a CD36 recognition protein on Plasmodium falciparum malaria-infected erythrocytes identified by anti-idiotype antibodies
CF Ockenhouse, FW Klotz, NN Tandon, GA Jamieson |
Proceedings of the National Academy of Sciences | 1991 |
CD36-mediated signal transduction in human monocytes by anti-CD36 antibodies but not by anti-thrombospondin antibodies recognizing cell membrane-bound thrombospondin
BJ Schüepp, H Pfister, KJ Clemetson, RL Silverstein, TW Jungi |
Biochemical and Biophysical Research Communications | 1991 |
Thrombospondin-exposed human monocytes display augmented luminol-enhanced chemiluminescence upon receptor triggering
BJ Schüepp, TW Jungi |
Biochemical and Biophysical Research Communications | 1991 |
Cytoadherence of knobby and knobless Plasmodium falciparum-infected erythrocytes
W Ruangjirachuporn, BA Afzelius, S Paulie, M Wahlgren, K Berzins, P Perlmann |
Parasitology | 1991 |
Plasmodium falciparum: The effect of pH and Ca2+ concentration on the in vitro cytoadherence of infected erythrocytes to amelanotic melanoma cells
I Crandall, H Smith, IW Sherman |
Experimental Parasitology | 1991 |
International Review of Cytology
RA Miller |
International Review of Cytology | 1991 |
Knobs, knob proteins and cytoadherence in falciparum malaria
YD Sharma |
International Journal of Biochemistry | 1991 |
Disruption of plasmodium falciparum-infected erythrocyte cytoadherence to human melanoma cells with inhibitors of glycoprotein processing
PS Wright, DE Cross-Doersen, KK Schroeder, TL Bowlin, PP McCann, AJ Bitonti |
Biochemical Pharmacology | 1991 |
Knob-independent cytoadherence of Plasmodium falciparum to the leukocyte differentiation antigen CD36
BA Biggs, L Goozé, K Wycherley, D Wilkinson, AW Boyd, KP Forsyth, L Edelman, GV Brown, JH Leech |
Journal of Experimental Medicine | 1990 |
Severe and complicated malaria
WH Organization |
Transactions of the Royal Society of Tropical Medicine and Hygiene | 1990 |
Falciparum malaria parasitized erythrocytes bind to a carboxy-terminal thrombospondin fragment and not the amino-terminal heparin-binding region
JA Sherwood, DD Roberts, SL Spitalnik, JW Lawler, LH Miller, RJ Howard |
Molecular and Biochemical Parasitology | 1990 |
Human cerebral malaria: association with erythrocyte rosetting and lack of anti-rosetting antibodies
J Carlson, H Helmby, M Wahlgren, J Carlson, H Helmby, M Wahlgren, AV Hill, D Brewster, BM Greenwood |
The Lancet | 1990 |
Plasmodium falciparum: A rapid assay for cytoadherence of [3H]hypoxanthine-labeled infected erythrocytes to human melanoma cells
PS Wright, D Cross-Doersen, PP McCann, AJ Bitonti |
Experimental Parasitology | 1990 |
Sequestration in Plasmodium falciparum malaria: Sticky cells and sticky problems
AR Berendt, DJ Ferguson, CI Newbold |
Parasitology Today | 1990 |
PAS IV, an integral membrane protein of mammary epithelial cells, is related to platelet and endothelial cell CD36 (GP IV)
DE Greenwalt, KW Watt, OY So, N Jiwani |
Biochemistry | 1990 |
Structural, functional, and antigenic differences between bovine heart endothelial CD36 and human platelet CD36
DE Greenwalt, KW Watt, T Hasler, RJ Howard, S Patel |
The Journal of biological chemistry | 1990 |
Cytoadherence and sequestration in falciparum malaria
JW Barnwell |
Experimental Parasitology | 1989 |