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Thrombin is an important mediator of platelet aggregation in stenosed canine coronary arteries with endothelial injury.

J F Eidt, … , L M Buja, J T Willerson

J F Eidt, … , L M Buja, J T Willerson

Published July 1, 1989
Citation Information: J Clin Invest. 1989;84(1):18-27. https://doi.org/10.1172/JCI114138.

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Coronary Microembolization A Skyschally, R Erbel, G Heusch	Circulation Journal	2003
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Heparin Cofactor II Inhibits Thrombus Formation in a Rat Thrombosis Model K Yamanaga, T Yuuki, M Tsukada, H Koshiba, T Nakajima, K Takechi, N Nakamura	Thrombosis Research	2000
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Pulse Dispersion due to Atrial Fibrillation Causes Arterial Thrombosis in a Rabbit Experimental Model N Kamiyama, Y Koyama, Y Saito, M Akiyama, T Akasaka, K Yoshida	Japanese Circulation Journal	2000
Recognition of the Importance of Embolization in Atherosclerotic Vascular Disease EJ Topol, JS Yadav	Circulation	2000
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Comparative Study of Antiplatelet Drugs in Vitro Y Matsumoto, K Marukawa, H Okumura, T Adachi, T Tani, Y Kimura	Thrombosis Research	1999
Solid phase chemistry approach to the SAR development of a novel class of active site-directed thrombin inhibitors MG Johnson, DD Bronson, JE Gillespie, DS Gifford-Moore, K Kalter, MP Lynch, JR McCowan, CC Redick, DJ Sall, GF Smith, RJ Foglesong	Tetrahedron	1999
Endothelial Injuries of Coronary Arteries Distal to Thrombotic Sites: Role of Adhesive Interaction Between Endothelial P-Selectin and Leukocyte Sialyl Lewis X H Eguchi, H Ikeda, T Murohara, H Yasukawa, N Haramaki, S Sakisaka, T Imaizumi	Circulation research	1999
Adhesive Interaction Between P-Selectin and Sialyl Lewis x Plays an Important Role in Recurrent Coronary Arterial Thrombosis in Dogs H Ikeda, T Ueyama, T Murohara, H Yasukawa, N Haramaki, H Eguchi, A Katoh, Y Takajo, I Onitsuka, T Ueno, SJ Tojo, T Imaizumi	Arteriosclerosis, thrombosis, and vascular biology	1999
Volatile anaesthetics reduce adhesion of blood platelets under low-flow conditions in the coronary system of isolated guinea pig hearts B Heindl, BF Becker, S Zahler, PF Conzen	Acta Anaesthesiologica Scandinavica	1998
The cleaved peptide of the thrombin receptor is a strong platelet agonist MI Furman, L Liu, SE Benoit, RC Becker, MR Barnard, AD Michelson	Proceedings of the National Academy of Sciences	1998
Effect of direct thrombin inhibition with Bivalirudin (Hirulog) on restenosis after coronary angioplasty JE Burchenal, DS Marks, JT Mann, MJ Schweiger, MT Rothman, P Ganz, B Adelman, JA Bittl	The American Journal of Cardiology	1998
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Dissolution of Mural Thrombus by Specific Thrombin Inhibition With r-Hirudin: Comparison With Heparin and Aspirin BJ Meyer, JJ Badimon, JH Chesebro, JT Fallon, V Fuster, L Badimon	Circulation	1998
Early Plus Delayed Hirudin Reduces Restenosis in the Atherosclerotic Rabbit More Than Early Administration Alone: Potential Implications for Dosing of Antithrombin Agents LM Thome, LW Gimple, BG Bachhuber, CA McNamara, M Ragosta, SD Gertz, ER Powers, GK Owens, JE Humphries, IJ Sarembock	Circulation	1998
Inhibition of Repetitive Thrombus Formation in the Stenosed Canine Coronary Artery by Enoxaparin, But Not by Unfractionated Heparin RJ Leadley, CJ Kasiewski, JS Bostwick, R Bentley, CT Dunwiddie, MH Perrone	Arteriosclerosis, thrombosis, and vascular biology	1998
Antithrombotic Effect of Crotalin, a Platelet Membrane Glycoprotein Ib Antagonist From Venom of Crotalus atrox MC Chang, HK Lin, HC Peng, TF Huang	Blood	1998
No Effect of Clot Age or Thrombolysis on Argatroban’s Inhibition of Thrombin RR Hantgan, WG Jerome, MJ Hursting	Blood	1998
Guidelines for the Management of Patients with Acute Myocardial Infarction A Salvioni, GB Perego, G Marenzi, S Galli, E Assanelli, MD Becker	Journal of Thrombosis and Thrombolysis	1998
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Thrombin Generation in Patients with Acute Myocardial Infarction Treated with Front-Loaded rt-PA and Recombinant Hirudin (HBW 023) Zeymer, Mateblowski, Neuhaus	Journal of Thrombosis and Thrombolysis	1998
Comparison of Argatroban and Hirudin for the Reperfusion of Thrombotic Arterial Occlusion by Tissue Plasminogen Activator Boeve, Reed, de Oliveira NC, Titus, Janssens, Giugliano, Torchiana, Daggett, Schwarz, Jang	Journal of Thrombosis and Thrombolysis	1998
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Failure of heparin to inhibit the expression of the thrombin receptor following endothelial injury of the rabbit carotid artery AF Guitteny, JM Herbert	European Journal of Pharmacology	1997
ADJUVANT EFFECT OF ARGATROBAN ON STAPHYLOKINASE INDUCED THROMBOLYSIS OF PLATELET RICH THROMBI IN RAT MESENTERIC VENULES IN VIVO M Kawano, S Watanabe, Y Sasaki, JC Giddings, J Yamamoto	Thrombosis Research	1997
Advances in Molecular and Cell Biology KJ Clemetson	Advances in Molecular and Cell Biology	1997
James Thornton Willerson, MD: A Conversation With the Editor WC MD	The American Journal of Cardiology	1997
Synthesis and biological activity of P2–P4 azapeptidomimetic P1-argininal and P1-ketoargininamide derivatives: a novel class of serine protease inhibitors JE Semple, DC Rowley, TK Brunck, WC Ripka	Bioorganic & Medicinal Chemistry Letters	1997
Antithrombotic effects in a rat model of aspirin-insensitive arterial thrombosis of desethyl KBT-3022, the main active metabolite of a new antiplatelet agent, KBT-3022 M Shimazawa, Y Takiguchi, K Umemura, K Kondo, M Nakashima	European Journal of Pharmacology	1997
State-of-the-Art Review: The Preclinical and Clinical Pharmacology of Novastan (Argatroban): A Small-Molecule, Direct Thrombin Inhibitor RP Schwarz, JC Becker, RL Brooks, MJ Hursting, JL Joffrion, GD Knappenberger, TP Kogan, PW Kogan, AA McKinney	Clinical and Applied Thrombosis/Hemostasis	1997
Profound and Sustained Inhibition of Platelet Aggregation by Fradafiban, a Nonpeptide Platelet Glycoprotein IIb/IIIa Antagonist, and Its Orally Active Prodrug, Lefradafiban, in Men TH Müller, H Weisenberger, R Brickl, H Narjes, F Himmelsbach, J Krause	Circulation	1997
A Tissue Plasminogen Activator/P-Selectin Fusion Protein Is an Effective Thrombolytic Agent K Fujise, BM Revelle, L Stacy, EL Madison, ET Yeh, JT Willerson, PJ Beck	Circulation	1997
Effects of Monoclonal Antibody to P-Selectin and Analogue of Sialyl Lewis X on Cyclic Flow Variations in Stenosed and Endothelium-Injured Canine Coronary Arteries T Ueyama, H Ikeda, N Haramaki, K Kuwano, T Imaizumi	Circulation	1997
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Textbook of Coronary Thrombosis and Thrombolysis RC Becker		1997
Discovery of a Novel, Selective, and Orally Bioavailable Class of Thrombin Inhibitors Incorporating Aminopyridyl Moieties at the P1 Position DM Feng, SJ Gardell, SD Lewis, MG Bock, Z Chen, RM Freidinger, AM Naylor-Olsen, HG Ramjit, R Woltmann, EP Baskin, JJ Lynch, R Lucas, JA Shafer, KB Dancheck, IW Chen, SS Mao, JA Krueger, TR Hare, AM Mulichak, JP Vacca	Journal of Medicinal Chemistry	1997
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Tumor necrosis factor decreases thrombin receptor expression in endothelial cells W Yan, C Tiruppathi, R Qiao, H Lum, AB Malik	Journal of Cellular Physiology	1996
Low-Molecular-Weight Heparin (Fragmin) and Thrombin Active-Site Inhibitor (Argatroban) Compared in Experimental Arterial and Venous Thrombosis and Bleeding Time WA Schumacher, CL Heran, TE Steinbacher	Journal of Cardiovascular Pharmacology	1996
Differential progression of complex culprit stenoses in patients with stable and unstable angina pectoris L Chen, MR Chester, R Crook, JC Kaski	Journal of the American College of Cardiology	1996
Antithrombotic actions of the thrombin inhibitor, argatroban, in a canine model of coronary cyclic flow: comparison with heparin N Duval, C Lunven, DP O'Brien, A Grosset, SE O'Connor, CN Berry	British Journal of Pharmacology	1996
AUTOANTIBODIES TO KININOGEN-PHOSPHATIDYLETHANOLAMINE COMPLEXES AUGMENT THROMBIN-INDUCED PLATELET AGGREGATION T Sugi, JA McIntyre	Thrombosis Research	1996
Sustained-release local hirulog therapy decreases early thrombosis but not neointimal thickening after arterial stenting DW Muller, D Gordon, EJ Topol, RJ Levy, G Golomb	American Heart Journal	1996
Effect of Thrombin Inhibition With Desulfatohirudin on Early Kinetics of Cellular Proliferation After Balloon Angioplasty in Atherosclerotic Rabbits M Ragosta, WL Barry, LW Gimple, SD Gertz, KW McCoy, GA Stouffer, CA McNamara, ER Powers, GK Owens, IJ Sarembock	Circulation	1996
Triggering of Acute Coronary Syndromes SN Willich, JE Muller		1996
Potent and Selective Thrombin Inhibitors Incorporating the Constrained Arginine Mimic l -3-Piperidyl( N -guanidino)alanine at P 1 OE Levy, JE Semple, ML Lim, J Reiner, WE Rote, E Dempsey, BM Richard, E Zhang, A Tulinsky, WC Ripka, RF Nutt	Journal of Medicinal Chemistry	1996
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Novel antithrombotic strategies for the treatment of coronary artery thrombosis: A critical appraisal PR Eisenberg	Journal of Thrombosis and Thrombolysis	1995
Thrombin generation and activity during thrombolysis and concomitant heparin therapy in patients with acute myocardial infarction PA Merlini, KA Bauer, L Oltrona, D Ardissino, A Spinola, M Cattaneo, M Broccolino, PM Mannucci, RD Rosenberg	Journal of the American College of Cardiology	1995
Binding of Biotinylated Thrombin Receptor Peptide to Cloned Human Thrombin Receptor Overexpressed in Baby Hamster Kidney Cells M Takada, O Ito, M Kogushi, H Kobayashi, T Yamada, H Tanaka, S Yoshitake, I Saito	Journal of Receptors and Signal Transduction	1995
Antithrombotic effect of a novel recombinant hirudin analogue, CX-397, in a rat arterial thrombosis model Y Takiguchi, F Asai, K Wada, H Hayashi, M Nakashima	British Journal of Pharmacology	1995
Conversion from chronic to acute coronary heart disease syndromes. Role of platelets and platelet products JT Willerson	Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital	1995
Gene therapy to restore prostacyclin presence to injured endothelium JT Willerson, P Zoldhelyi, R Meidell, J McNatt, XM Xu, KK Wu	Transactions of the American Clinical and Climatological Association	1995
The combination of thrombin inhibitor and thromboxane synthase inhibitor on experimental thrombosis and bleeding H Kawai, Y Tamao	Thrombosis Research	1995
Effect of argatroban on thrombus formation during acute coronary occlusion after balloon angioplasty S Suzuki, S Sakamoto, K Adachi, K Mizutani, M Koide, N Ohga, T Miki, T Matsuo	Thrombosis Research	1995
Thrombin induces production in human umbilical vein endothelial cells K Murakami, A Ueno, K Yamanouchi, T Kondo	Thrombosis Research	1995
Immunopharmacology of Platelets MH Kroll, AI Schafer	Immunopharmacology of Platelets	1995
Contrast Media Effects on Hemostatic and Thrombotic Parameters: Possible Consequences for Practical Techniques and Prophylactic Measures H Stormorken, KS Sakariassen	Acta Radiologica	1995
Effect of thrombin inhibition on patients with peripheral arterial obstructive disease: A multicenter clinical trial of argatroban T Matsuo, K Kario, S Matsuda, N Yamaguchi, E Kakishita	Journal of Thrombosis and Thrombolysis	1995
Measurement of Platelet-Activating Factor in a Canine Model of Coronary Thrombosis and in Endarterectomy Samples From Patients With Advanced Coronary Artery Disease HW Mueller, CA Haught, JM McNatt, K Cui, SJ Gaskell, DA Johnston, JT Willerson	Circulation research	1995
Effect of Selective Factor Xa Inhibition on Arterial Thrombus Formation Triggered by Tissue Factor/Factor VIIa or Collagen in an Ex Vivo Model of Shear-Dependent Human Thrombogenesis U Ørvim, RM Barstad, GP Vlasuk, KS Sakariassen	Arteriosclerosis, thrombosis, and vascular biology	1995
An Antibody Against the Exosite of the Cloned Thrombin Receptor Inhibits Experimental Arterial Thrombosis in the African Green Monkey JJ Cook, GR Sitko, B Bednar, C Condra, MJ Mellott, DM Feng, RF Nutt, JA Shafer, RJ Gould, TM Connolly	Circulation	1995
Blockade of Platelet GPIIb/IIIa Receptors as an Antithrombotic Strategy BS Coller	Circulation	1995
Cardiovascular Disease 2 LL Gallo		1995
Inhibitory Effect of Clopidogrel, Vapiprost and Argatroban on the Middle Cerebral Artery Thrombosis in the Rat K Umemura, H Kawai, H Ishihara, M Nakashima	The Japanese Journal of Pharmacology	1995
Effect of Argatroban on Microthrombi Formation and Brain Damage in the Rat Middle Cerebral Artery Thrombosis Model H Kawai, K Umemura, M Nakashima	The Japanese Journal of Pharmacology	1995
Thrombin generation in human coronary arteries after percutaneous transluminal balloon angioplasty JD Marmur, SK Sharma, N Khaghan, SR Torre, DH Israel, PA Merlini, D Ardissino, JA Ambrose	Journal of the American College of Cardiology	1994
Free oxygen radicals contribute to platelet aggregation and cyclic flow variations in stenosed and endothelium-injured canine coronary arteries H Ikeda, Y Koga, T Oda, K Kuwano, H Nakayama, T Ueno, H Toshima, LH Michael, ML Entman	Journal of the American College of Cardiology	1994
Specific Thrombin Inhibitors in Vivo D Fitzgerald	Annals of the New York Academy of Sciences	1994
New recombinant glycosylated prourokinase for treatment of patients with acute myocardial infarction WD Weaver, JR Hartmann, JL Anderson, PS Reddy, JC Sobolski, AA Sasahara	Journal of the American College of Cardiology	1994
Failure of fixed dose intravenous heparin to suppress increases in thrombin activity after coronary thrombolysis with streptokinase M Galvani, DR Abendschein, D Ferrini, F Ottani, F Rusticali, PR Eisenberg	Journal of the American College of Cardiology	1994
Thrombin and antithrombotic therapy in interventional cardiology JP Herrman, PW Serruys	Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital	1994
Inhibition of factor Xa-induced platelet aggregation by a selective thrombin inhibitor, argatroban H Kawai, T Yamamoto, H Hara, Y Tamao	Thrombosis Research	1994
The antithrombotic effect of human activated protein c on He-Ne laser-induced thrombosis in rat mesenteric microvessels T Yamashita, A Matsuoka, A Funatsu, J Yamamoto	Thrombosis Research	1994
The in vitro pharmacological profile of SK&F 106760, a novel GPIIB/IIIA antagonist AJ Nichols, JA Vasko, RE Valocik, LJ Kopaciewicz, BL Storer, FE Ali, T Romoff, R Calvo, JM Samanen	Thrombosis Research	1994
Human neutrophil cathepsin G is a potent platelet activator CA LaRosa, MJ Rohrer, SE Benoit, LJ Rodino, MR Barnard, AD Michelson	Journal of Vascular Surgery	1994
Platelet-induced vasomotion of isolated canine coronary artery in the presence of halothane or isoflurane GA Blaise, M Parent, S Laurin, A Omri, TA Reader, JM Moutquin	Journal of Cardiothoracic and Vascular Anesthesia	1994
Thrombin receptor function and cardiovascular disease SR Coughlin	Trends in Cardiovascular Medicine	1994
Pharmacology of Current and Future Antithrombotic Therapies TH Müller, K Binder, BD Guth	Cardiology Clinics	1994
Pathogenesis of acute myocardial infarction. Novel regulatory systems of bioactive substances in the vessel wall C Kawai	Circulation	1994
Inhibition of growth of thrombus on fresh mural thrombus. Targeting optimal therapy BJ Meyer, JJ Badimon, A Mailhac, A Fernández-Ortiz, JH Chesebro, V Fuster, L Badimon	Circulation	1994
Thrombin plays a key role in late platelet thrombus growth and/or stability. Effect of a specific thrombin inhibitor on thrombogenesis induced by aortic subendothelium exposed to flowing rabbit blood A Gast, TB Tschopp, HR Baumgartner	Arteriosclerosis Thrombosis and Vascular Biology	1994
Persistent thrombin generation in humans during specific thrombin inhibition with hirudin P Zoldhelyi, J Bichler, WG Owen, DE Grill, V Fuster, JS Mruk, JH Chesebro	Circulation	1994
Platelet activation results in a redistribution of glycoprotein IV (CD36) AD Michelson, JD Wencel-Drake, AS Kestin, MR Barnard	Arteriosclerosis Thrombosis and Vascular Biology	1994
Tissue-type plasminogen activator and its inhibitor in rat aorta. Effect of endotoxin T Padró, PH Quax, CM van den Hoogen, P Roholl, JH Verheijen, JJ Emeis	Arteriosclerosis Thrombosis and Vascular Biology	1994
Arterial diastolic pressure augmentation by intra-aortic balloon counterpulsation enhances the onset of coronary artery reperfusion by thrombolytic therapy PA Gurbel, RD Anderson, CS MacCord, H Scott, SF Komjathy, J Poulton, JL Stafford, J Godard	Circulation	1994
Thrombin in inflammation and healing: relevance to rheumatoid arthritis R Morris, PG Winyard, DR Blake, CJ Morris	Annals of the rheumatic diseases	1994
The Modern Era of Coronary Thrombolysis RC Becker		1994
Thrombin receptor-activating peptides differentially stimulate platelet-derived growth factor production, monocytic cell adhesion, and E-selectin expression in human umbilical vein endothelial cells R Shankar, CA de la Motte, EJ Poptic, PE DiCorleto	The Journal of biological chemistry	1994
Surface 12-Lead Electrocardiographic Findings and Plasma Markers of Thrombin Activity and Generation in Patients with Myocardial Ischemia at Rest Becker, Tracy, Bovill, Corrao, Baker, Ball, Mann	Journal of Thrombosis and Thrombolysis	1994
Platelet Activation Determined by Flow Cytometry Persists Despite Antithrombotic Therapy in Patients with Unstable Angina and Non-Q-Wave Myocardial Infarction Becker, Bovill, Corrao, Ball, Ault, Mann, Tracy	Journal of Thrombosis and Thrombolysis	1994
Evidence for a rebound coagulation phenomenon after cessation of a 4-hour infusion of a specific thrombin inhibitor in patients with unstable angina pectoris HK Gold, FW Torres, HD Garabedian, W Werner, IK Jang, A Khan, JN Hagstrom, T Yasuda, RC Leinbach, JB Newell, EG Bovill, DC Stump, D Collen	Journal of the American College of Cardiology	1993
Thrombin inhibitors in unstable angina: Rebound or continuation of angina after argatroban withdrawal? JT Willerson, W Casscells	Journal of the American College of Cardiology	1993
Biologic effects of recombinant hirudin (CGP 39393) in human volunteers M Verstraete, M Nurmohamed, J Kienast, M Siebeck, G Silling-Engelhardt, H Büller, B Hoet, J Bichler, P Close	Journal of the American College of Cardiology	1993
Thrombus and unstable angina W Casscells, JJ Ferguson, JT Willerson, RD Fish, G Schroth, R Smalling, HV Anderson, W Casscells, JT Willerson, LM Buja	The Lancet	1993
Evidence for common structural changes in thrombin induced by active-site or exosite binding MA Parry, SR Stone, J Hofsteenge, MP Jackman	Biochemical Journal	1993
Mr 6,400 aurin tricarboxylic acid directly activates platelets Z Guo, MJ Weinstein, MD Phillips, MH Kroll	Thrombosis Research	1993
The antithrombotic effect of low molecular weight synthetic thrombin inhibitors, argatroban and PPACK, on He-Ne laser-induced thrombosis in rat mesenteric microvessels T Yamashita, J Yamamoto, Y Sasaki, A Matsuoka	Thrombosis Research	1993
Activation of the hemostatic system during thrombolytic therapy PA Merlini, M Cattaneo, A Spinpla, D Ardissino, L Oltrona, C Belli, PM Mannucci	The American Journal of Cardiology	1993
Effect of strenuous exercise on platelet activation state and reactivity AS Kestin, PA Ellis, MR Barnard, A Errichetti, BA Rosner, AD Michelson	Circulation	1993
Comparison of hirudin and heparin as adjuncts to streptokinase thrombolysis in a canine model of coronary thrombosis DF Rigel, RW Olson, RW Lappe	Circulation research	1993
Short-term and long-term role of platelet activating factor as a mediator of in vivo platelet aggregation P Golino, G Ambrosio, M Ragni, I Pascucci, M Triggiani, A Oriente, J McNatt, LM Buja, M Condorelli, M Chiariello	Circulation	1993
Illusion of reperfusion. Does anyone achieve optimal reperfusion during acute myocardial infarction? AM Lincoff, EJ Topol	Circulation	1993
Combined use of aspirin and heparin inhibits in vivo acute carotid thrombosis ZS Huang, CM Teng, TK Lee, CT Shun, CY Wang	Stroke; a journal of cerebral circulation	1993
Use of a direct antithrombin, hirulog, in place of heparin during coronary angioplasty EJ Topol, R Bonan, D Jewitt, U Sigwart, VV Kakkar, M Rothman, D de Bono, J Ferguson, JT Willerson, J Strony	Circulation	1993
The Design of Synthetic Inhibitors of Thrombin G Claeson, MF Scully, VV Kakkar, J Deadman		1993
Nuclear Imaging in Drug Discovery, Development, and Approval HD Burns, RE Gibson, RF Dannals, PK Siegl		1993
Serotonin: From Cell Biology to Pharmacology and Therapeutics PM Vanhoutte, PR Saxena, R Paoletti, N Brunello, AS Jackson		1993
Effects of trimetazidine on in vivo coronary arterial platelet thrombosis. Belcher PR, Drake-Holland AJ, Hynd JW, Noble MI	Cardiovascular Drugs and Therapy	1993
Characterization of a functional thrombin receptor. Issues and opportunities SR Coughlin, TK Vu, DT Hung, VI Wheaton	Journal of Clinical Investigation	1992
Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation DT Hung, TK Vu, VI Wheaton, K Ishii, SR Coughlin	Journal of Clinical Investigation	1992
Thrombin receptor expression in normal and atherosclerotic human arteries NA Nelken, SJ Soifer, J O'Keefe, TK Vu, IF Charo, SR Coughlin	Journal of Clinical Investigation	1992
Dynamics in Thrombus Formation E Falk	Annals of the New York Academy of Sciences	1992
Antiplatelet and anticoagulant drugs in coronary vascular disease GA FitzGerald, E Shipp	Annals of Epidemiology	1992
Hereditary heparin cofactor II deficiency and coronary artery disease T Matsuo, K Kario, S Sakamoto, T Yamada, T Miki, T Hirase, H Kobayashi	Thrombosis Research	1992
Reactivation of Unstable Angina after the Discontinuation of Heparin P Théroux, D Waters, J Lam, M Juneau, J McCans	New England Journal of Medicine	1992
Recurrent myocardial ischemia following thrombolytic therapy: guidelines for practicing clinicians RC Becker	American Heart Journal	1992
High-dose aspirin inhibits shear-induced platelet reaction involving thrombin generation CP Ratnatunga, SF Edmondson, GM Rees, IB Kovacs	Circulation	1992
Endothelium-derived relaxing factor modulates platelet aggregation in an in vivo model of recurrent platelet activation P Golino, M Cappelli-Bigazzi, G Ambrosio, M Ragni, E Russolillo, M Condorelli, M Chiariello	Circulation research	1992
Selective factor Xa inhibition by recombinant antistasin prevents vascular graft thrombosis in baboons LW Schaffer, JT Davidson, GP Vlasuk, CT Dunwiddie, PK Siegl	Arteriosclerosis Thrombosis and Vascular Biology	1992
Tethered ligand agonist peptides. Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function RM Scarborough, MA Naughton, W Teng, DT Hung, J Rose, TK Vu, VI Wheaton, CW Turck, SR Coughlin	The Journal of biological chemistry	1992
Molecular cloning of the rat vascular smooth muscle thrombin receptor. Evidence for in vitro regulation by basic fibroblast growth factor C Zhong, DJ Hayzer, MA Corson, MS Runge	The Journal of biological chemistry	1992
Streptokinase Inhibits Acute Platelet Thrombus Formation in Stenosed Dog Coronary Arteries JD Folts, BS Schwartz, MH Kroll, AI Schafer	Platelets	1991
Argatroban, A Selective, Potent Thrombin Inhibitor LR Bush	Cardiovascular Drug Reviews	1991
Monoclonal Antibodies to Platelet Glycoprotein IIb/IIIa as Antithrombotic Agents BS Coller, LE Scudder, J Beer, HK Gold, JD Folts, J Cavagnaro, R Jordan, C Wagner, J Iuliucci, D Knight, J Ghrayeb, C Smith, HF Weisman, H Berger	Annals of the New York Academy of Sciences	1991
Concurrent nitroglycerin administration decreases thrombolytic potential of tissue-type plasminogen activator JL Mehta, FA Nicolini, WW Nichols, TG Saldeen, AC Wilson, LV Thompson	Journal of the American College of Cardiology	1991
Spontaneous alterations in coronary blood flow velocity before and after coronary angioplasty in patients with severe angina EJ Eichhorn, PA Grayburn, JE Willard, HV Anderson, JB Bedotto, M Carry, JK Kahn, JT Willerson	Journal of the American College of Cardiology	1991
Overview: Current Status of Thrombolytic Therapy in Acute Myocardial Infarction T Yasuda	Expert Opinion on Therapeutic Patents	1991
The 29-kDa proteins phosphorylated in thrombin-activated human platelets are forms of the estrogen receptor-related 27-kDa heat shock protein ME Mendelsohn, Y Zhu, S O'Neill	Proceedings of the National Academy of Sciences	1991
Documentation of experimentally induced thrombus formation using intravascular ultrasound JJ Ferguson, JC Ober, SK Edelman, LM Buja, JT Willerson	Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital	1991
Unstable angina pectoris and the progression to acute myocardial infarction. Role of platelets and platelet-derived mediators JT Willerson, SK Yao, JJ Ferguson, HV Anderson, P Golino, LM Buja	Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital	1991
Acute carotid artery occlusive thrombosis and its pharmacological prevention in the rabbit C Bevilacqua, M Finesso, M Prosdocimi	Thrombosis Research	1991
Monoclonal Antibodies to Platelet Glycoprotein IIb/IIIa as Antithrombotic Agentsa BS Coller, LE Scudder, J Beer, HK Gold, JD Folts, J Cavagnaro, R Jordan, C Wagner, J Iuliucci, D Knight, J Ghrayeb, C Smith, HF Weisman, H Berger	Annals of the New York Academy of Sciences	1991
Coronary thrombosis: Pathogenesis and clinical manifestations E Falk	The American Journal of Cardiology	1991
New Horizons in the Treatment of Coronary Artery Thrombosis MS Runge	The American Journal of the Medical Sciences	1991
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation T K Vu, D T Hung, V I Wheaton, S R Coughlin	Cell	1991
Combined administration of aspirin and a specific thrombin inhibitor in man RJ Clarke, G Mayo, GA FitzGerald, DJ Fitzgerald	Circulation	1991
Antithrombotic efficacy of recombinant tick anticoagulant peptide. A potent inhibitor of coagulation factor Xa in a primate model of arterial thrombosis LW Schaffer, JT Davidson, GP Vlasuk, PK Siegl	Circulation	1991
Differential effects of thromboxane A2 synthase inhibition, singly or combined with thromboxane A2/prostaglandin endoperoxide receptor antagonism, on occlusive thrombosis elicited by endothelial cell injury or by deep vascular damage in canine coronary arteries G Vandeplassche, C Hemans, AV de Water, R Xhonneux, L Wouters, KV Ammel, FD Clerck	Circulation research	1991
Effectiveness of recombinant desulphatohirudin in reducing restenosis after balloon angioplasty of atherosclerotic femoral arteries in rabbits IJ Sarembock, SD Gertz, LW Gimple, RM Owen, ER Powers, WC Roberts	Circulation	1991
Prevention of arterial reocclusion after thrombolysis with recombinant lipoprotein-associated coagulation inhibitor EJ Haskel, SR Torr, KC Day, MO Palmier, TC Wun, BE Sobel, DR Abendschein	Circulation	1991
Thrombin-induced platelet aggregates have a dynamic structure. Time-dependent redistribution of glycoprotein IIb-IIIa complexes and secreted adhesive proteins E Heilmann, P Hourdillé, A Pruvost, A Paponneau, AT Nurden	Arteriosclerosis Thrombosis and Vascular Biology	1991
Relative efficacy of antithrombin compared with antiplatelet agents in accelerating coronary thrombolysis and preventing early reocclusion EJ Haskel, NA Prager, BE Sobel, DR Abendschein	Circulation	1991
Hirudin and nitrates inhibit the thrombin-induced release of endothelin from the intact porcine aorta CM Boulanger, TF Lüscher	Circulation research	1991
Comparative effects of aspirin, a synthetic thrombin inhibitor and a monoclonal antiplatelet glycoprotein IIb/IIIa antibody on coronary artery reperfusion, reocclusion and bleeding with recombinant tissue-type plasminogen activator in a canine preparation T Yasuda, HK Gold, H Yaoita, RC Leinbach, JL Guerrero, IK Jang, R Holt, JT Fallon, D Collen	Journal of the American College of Cardiology	1990
Ultrathrombolysis EJ Topol	Journal of the American College of Cardiology	1990
In vivo thrombin inhibition enhances and sustains arterial recanalization with recombinant tissue-type plasminogen activator IK Jang, HK Gold, RC Leinbach, JT Fallon, D Collen	Circulation research	1990
Dietary fish oil accelerates the response to coronary thrombolysis with tissue-type plasminogen activator. Evidence for a modest platelet inhibitory effect in vivo GA Braden, HR Knapp, DJ Fitzgerald, GA FitzGerald	Circulation	1990
Aurintricarboxylic acid in a canine model of coronary artery thrombosis J Strony, M Phillips, D Brands, J Moake, B Adelman	Circulation	1990
Prevention of thrombosis and rethrombosis. New approaches MS Runge	Circulation	1990

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