JCI - Citations to Mechanism of Hb F stimulation by S-stage compounds. In vitro studies with bone marrow cells exposed to 5-azacytidine, Ara-C, or hydroxyurea.

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Mechanism of Hb F stimulation by S-stage compounds. In vitro studies with bone marrow cells exposed to 5-azacytidine, Ara-C, or hydroxyurea.

R Galanello, … , G Stamatoyannopoulos, T Papayannopoulou

Published April 1, 1988
Citation Information: J Clin Invest. 1988;81(4):1209-1216. https://doi.org/10.1172/JCI113437.

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Citations to this article (22)

Title and authors	Publication	Year
Salubrinal induces fetal hemoglobin expression via the stress-signaling pathway in human sickle erythroid progenitors and sickle cell disease mice Lopez NH, Li B, Palani C, Siddaramappa U, Takezaki M, Xu H, Zhi W, Pace BS	PloS one	2022
FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors L Makala, SD Maro, TF Lou, S Sivanand, JM Ahn, BS Pace	Anemia	2012
The proinflammatory cytokine GM-CSF downregulates fetal hemoglobin expression by attenuating the cAMP-dependent pathway in sickle cell disease T Ikuta, AD Adekile, DR Gutsaeva, JB Parkerson, SD Yerigenahally, B Clair, A Kutlar, N Odo, CA Head	Blood Cells Molecules and Diseases	2011
Enzymatic Methylation of DNA in Cultured Human Cells Studied by Stable Isotope Incorporation and Mass Spectrometry JL Herring, DK Rogstad, LC Sowers	Chemical Research in Toxicology	2009
Developmental- and differentiation-specific patterns of human gamma- and beta-globin promoter DNA methylation R Mabaera, CA Richardson, K Johnson, M Hsu, S Fiering, CH Lowrey	Blood	2007
Understanding mechanisms of γ-globin gene regulation to develop strategies for pharmacological fetal hemoglobin induction BS Pace, S Zein	Developmental Dynamics	2006
Control of globin gene expression during development and erythroid differentiation G Stamatoyannopoulos	Experimental Hematology	2005
Pharmacological Induction of Fetal Hemoglobin Synthesis using Histone Deacetylase Inhibitors H Cao	Hematology	2004
Mechanism for fetal globin gene expression: role of the soluble guanylate cyclase-cGMP-dependent protein kinase pathway T Ikuta, S Ausenda, MD Cappellini	Proceedings of the National Academy of Sciences	2001
Advances in experimental treatment of β-thalassaemia GP Rodgers, Y Saunthararajah	Expert Opinion on Investigational Drugs	2001
Mechanism for fetal globin gene expression: Role of the soluble guanylate cyclase-cGMP-dependent protein kinase pathway T Ikuta, S Ausenda, MD Cappellini	Proceedings of the National Academy of Sciences	2001
Pharmacologic Induction of Fetal Hemoglobin Synthesis: Cellular and Molecular Mechanisms YM Yang, B Pace	Pediatric Pathology & Molecular Medicine	2001
Fetal Erythropoiesis after Allogeneic Bone Marrow Transplantation Estimated by the Peripheral Blood Erythrocytes Containing Hemoglobin F (F-cells) J Meletis, M Dalekou, M Samarkos, E Paravasiliou, C Meletis, K Konstantopoulos, E Apostolidou, V Komninaka, E Terpos, O Benopoulou, K Korovesis, E Variami, D Loukopoulos	Hematology	2001
Reduction of the Clinical Severity of Sickle Cell/β-Thalassemia with Hydroxyurea: The Experience of a Single Center in Greece D Loukopoulos, E Voskaridou, V Kalotychou, M Schina, A Loutradi, I Theodoropoulos	Blood Cells, Molecules, and Diseases	2000
Butyrate-inducible elements in the human γ-globin promoter BS Pace, YR Chen, A Thompson, SR Goodman	Experimental Hematology	2000
Long-term hydroxyurea treatment in young sickle cell patients M Maier-Redelsperger, D Labie, J Elion	Current Opinion in Hematology	1999
UNDERSTANDING FETAL GLOBIN GENE EXPRESSION: A STEP TOWARDS EFFECTIVE HbF REACTIVATION IN HAEMOGLOBINOPATHIES SM Jane, JM Cunningham	British Journal of Haematology	1998
Alterations in Protein-DNA Interactions in the γ-Globin Gene Promoter in Response to Butyrate Therapy T Ikuta, YW Kan, PS Swerdlow, DV Faller, SP Perrine	Blood	1998
A Bioavailability and Pharmacokinetic Study of Oral and Intravenous Hydroxyurea GI Rodriguez, JG Kuhn, GR Weiss, SG Hilsenbeck, JR Eckardt, A Thurman, DA Rinaldi, S Hodges, DD Hoff, EK Rowinsky	Blood	1998
Transgenic mouse model of pharmacologic induction of fetal hemoglobin: Studies using a new ribonucleotide reductase inhibitor, didox BS Pace, HL Elford, G Stamatoyannopoulos	American Journal of Hematology	1994
Effects of hydroxyurea and cyclic adenosine monophosphate/protein kinase A inhibitors on the expression of the human chorionic gonadotropin alpha subunit and c-myc genes in choriocarcinoma JL Arbiser, ZK Arbiser, JA Majzoub	Journal of Endocrinological Investigation	1993
Impact of 5-azacytidine on insulin binding and insulin-induced receptor formation in Tetrahymena G Csaba, P Kovács	Biochemical and Biophysical Research Communications	1990

Citations to this article

Mechanism of Hb F stimulation by S-stage compounds. In vitro studies with bone marrow cells exposed to 5-azacytidine, Ara-C, or hydroxyurea.

Mechanism of Hb F stimulation by S-stage compounds. In vitro studies with bone marrow cells exposed to 5-azacytidine, Ara-C, or hydroxyurea.

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