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Citations to this article

Binding and covalent cross-linking of purified von Willebrand factor to native monomeric collagen.
P Bockenstedt, … , J McDonagh, R I Handin
P Bockenstedt, … , J McDonagh, R I Handin
Published August 1, 1986
Citation Information: J Clin Invest. 1986;78(2):551-556. https://doi.org/10.1172/JCI112608.
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Binding and covalent cross-linking of purified von Willebrand factor to native monomeric collagen.

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Abstract

We have analyzed the interaction of the adhesive glycoprotein, von Willebrand factor (vWF), with native monomeric collagen monolayers by adsorbing acid soluble Types I and III collagen derived from calf skin to polystyrene microtiter wells and incubating the wells with purified human 125I-vWF. The binding of 125I-vWF was saturable, reversible, specific, and was abolished by heat denaturation of the collagen monomers. Binding was half-maximal at 5 micrograms/ml, and, at saturation, 7.5 ng 125I-vWF were bound to each microgram of immobilized collagen. 125I-vWF did not bind to wells coated with other extracellular matrix or plasma proteins such as fibronectin, fibrinogen, gelatin, or the q subunit of the first component of complement (C1q). In addition, bound 125I-vWF could not be displaced from collagen by the addition of either fibronectin or fibrinogen. After incubation with Factor XIIIa, plasma transglutaminase, 125I-vWF bound to collagen could no longer be displaced by vWF, which suggests covalent cross-linking of vWF to collagen monomers. Factor XIIIa-dependent covalent cross-linking of vWF to collagen, but not to fibronectin or laminin, was also demonstrated by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate.

Authors

P Bockenstedt, J McDonagh, R I Handin

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Total citations by year

Year: 2016 2012 2007 2005 2003 2002 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 Total
Citations: 1 2 1 1 1 2 2 2 1 2 3 1 4 2 2 2 3 4 5 1 2 44
Citation information
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Citations to this article (44)

Title and authors Publication Year
Von Willebrand Factor Interacts with Surface-Bound C1q and Induces Platelet Rolling
R Kölm, M Schaller, LT Roumenina, I Niemiec, JA Hovinga, E Khanicheh, BA Kaufmann, H Hopfer, M Trendelenburg
Journal of immunology (Baltimore, Md. : 1950) 2016
Substrates of Factor XIII-A: roles in thrombosis and wound healing
VR Richardson, P Cordell, KF Standeven, AM Carter
Clinical Science 2012
Collagen XVI in health and disease
S Grässel, RJ Bauer
Matrix Biology 2012
The Potential Utility of Fibrin Sealant Dressing in Repair of Vascular Injury in Swine
BS Kheirabadi, EM Acheson, R Deguzman, JM Crissey, AV Delgado, SJ Estep, JB Holcomb
The Journal of Trauma: Injury, Infection, and Critical Care 2007
Hemostatic Efficacy of Two Advanced Dressings in an Aortic Hemorrhage Model in Swine
BS Kheirabadi, EM Acheson, R Deguzman, JL Sondeen, KL Ryan, A Delgado, EJ Dick, JB Holcomb
The Journal of Trauma: Injury, Infection, and Critical Care 2005
Mapping the Collagen-binding Site in the von Willebrand Factor-A3 Domain
RA Romijn, E Westein, B Bouma, ME Schiphorst, JJ Sixma, PJ Lenting, EG Huizinga
The Journal of biological chemistry 2003
Type XVI Collagen is Expressed in Factor XIIIa+ Monocyte-Derived Dermal Dendrocytes and Constitutes a Potential Substrate for Factor XIIIa
A Akagi, S Tajima, A Ishibashi, Y Matsubara, M Takehana, S Kobayashi, N Yamaguchi
Journal of Investigative Dermatology 2002
Role of factor XIII in fibrin clot formation and effects of genetic polymorphisms
RA Ariëns, TS Lai, JW Weisel, CS Greenberg, PJ Grant
Blood 2002
Proteolysis of Subendothelial Adhesive Glycoproteins (Fibronectin, Thrombospondin, and von Willebrand Factor) by Plasmin, Leukocyte Cathepsin G, and Elastase
A Bonnefoy, C Legrand
Thrombosis Research 2000
Identification of the Collagen-binding Site of the von Willebrand Factor A3-domain
RA Romijn, B Bouma, W Wuyster, P Gros, J Kroon, JJ Sixma, EG Huizinga
The Journal of biological chemistry 2000
Blood Coagulation Factor XIII
L Muszbek, VC Yee, Z Hevessy
Thrombosis Research 1999
Hämostaseologie
G Müller-Berghaus, B Pötzsch
Hämostaseologie 1999
The role of fibrin tissue adhesives in surgery of haemophilia patients
U Martinowitz, D Varon, M Heim
Haemophilia 1998
Crystal structure of the A3 domain of human von Willebrand factor: implications for collagen binding
EG Huizinga, RM van der Plas, J Kroon, JJ Sixma, P Gros
Structure 1997
Fibrin Sealant: Scientific Rationale, Production Methods, Properties, and Current Clinical Use
M Radosevich, HA Goubran, T Burnouf
Vox Sanguinis 1997
The A-Domain of Integrin alpha2 Binds Specifically to a Range of Collagens but is not a General Receptor for the Collagenous Motif
DS Tuckwell, KB Reid, MJ Barnes, MJ Humphries
European Journal of Biochemistry 1996
Role of Fibrin Sealants in Surgical Procedures on Patients With Hemostatic Disorders:
U Martinowitz, S Schulman, H Horoszowski, M Heim
Clinical Orthopaedics and Related Research 1996
Novel Aspects of Blood Coagulation Factor XIII. I. Structure, Distribution, Activation, and Function
L Muszbek, R Adany, H Mikkola
Critical Reviews in Clinical Laboratory Sciences 1996
Interaction of the von Willebrand Factor (vWF) with Collagen: LOCALIZATION OF THE PRIMARY COLLAGEN-BINDING SITE BY ANALYSIS OF RECOMBINANT vWF A DOMAIN POLYPEPTIDES
MA Cruz, H Yuan, JR Lee, RJ Wise, RI Handin
The Journal of biological chemistry 1995
beta1-integrin-mediated adhesion of melanoma cells to the propolypeptide of von Willebrand factor
J TAKAGI, Y SUDO, T SAITO, Y SAITO
European Journal of Biochemistry 1994
Immunohistochemical Localization of Factor XIIIa in Chronic Venous Insufficiency
W Vanscheidt, A Laubert, H Laaff, JM Weiss, E Schöpf
Phlebology / Venous Forum of the Royal Society of Medicine 1994
24. Hämophilie-Symposion
I Scharrer, W Schramm
1994
Direct binding of collagen to the I domain of integrin alpha 2 beta 1 (VLA-2, CD49b/CD29) in a divalent cation-independent manner
T Kamata, Y Takada
The Journal of biological chemistry 1994
Co-localization of von Willebrand factor and type VI collagen in human vascular subendothelium
JH Rand, XX Wu, BJ Potter, RR Uson, RE Gordon
The American Journal of Pathology 1993
Factor XIIIa-derived peptides inhibit transglutaminase activity. Localization of substrate recognition sites
KE Achyuthan, TF Slaughter, MA Santiago, JJ Enghild, CS Greenberg
The Journal of biological chemistry 1993
Propolypeptide and mature portions of von Willebrand factor of bovine origin recognize different sites on type-I collagen obtained from bovine tendon
T USUI, T FUJISAWA, J TAKAGI, Y SAITO
European Journal of Biochemistry 1992
Functional analysis of a recombinant glycoprotein Ib alpha polypeptide which inhibits von Willebrand factor binding to the platelet glycoprotein Ib-IX complex and to collagen
MA Cruz, E Petersen, SM Turci, RI Handin
The Journal of biological chemistry 1992
150-kD von Willebrand factor binding protein extracted from human vascular subendothelium is type VI collagen
JH Rand, ND Patel, E Schwartz, SL Zhou, BJ Potter
Journal of Clinical Investigation 1991
Effect of deletion of the A1 domain of von Willebrand factor on its binding to heparin, collagen and platelets in the presence of ristocetin
JJ SIXMA, ME SCHIPHORST, CL VERWEIJ, H PANNEKOEK
European Journal of Biochemistry 1991
Human platelet factor V is crosslinked to actin by FXIIIa during platelet activation by thrombin
DL Wang, AE Annamalai, S Ghosh, AM Gewirtz, RW Colman
Thrombosis Research 1990
Binding and degradation of blood coagulation factor XIII by cultured fibroblasts
EL Barry, DF Mosher
The Journal of biological chemistry 1990
Formation of high molecular weight dermatan sulfate proteoglycan in bovine aortic endothelial cell cultures. Evidence for transglutaminase-catalyzed cross-linking to fibronectin
MG Kinsella, TN Wight
The Journal of biological chemistry 1990
Factor XIIIa is expressed by fibroblasts in fibrovascular tumors*
AJ Nemeth, NS Penneys
Journal of Cutaneous Pathology 1989
Differing polarity of the constitutive and regulated secretory pathways for von Willebrand factor in endothelial cells
LA Sporn, VJ Marder, DD Wagner
The Journal of Cell Biology 1989
Glycocalicin binding to von Willebrand factor adsorbed onto collagen-coated or polystyrene surfaces
A Inbal, J Loscalzo
Thrombosis Research 1989
Factor XIIIa-mediated Cross-linking of Fibronectin in Fibroblast Cell Layers
EL Barry, DF Mosher
The Journal of biological chemistry 1989
”A“ subunit of factor XIII is present on bovine platelet membrane and mediates collagen-induced platelet activation
K Kasahara, J Takagi, F Sekiya, Y Inada, Y Saito
Thrombosis Research 1988
Characterization of the fibrin polymer structure that accelerates thrombin cleavage of plasma factor XIII
CS Greenberg, KE Achyuthan, S Rajagopalan, SV Pizzo
Archives of Biochemistry and Biophysics 1988
Platelet vinculin: a substrate of activated Factor XIII
GM Asijee, L Muszbek, J Kappelmayer, J Polgár, A Horváth, A Sturk
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 1988
Fibrous papule: A tumor of fibrohistiocytic cells that contain factor XIIIa
AJ Nemeth, NS Penneys, HB Bernstein
Journal of the American Academy of Dermatology 1988
Human Fibrinogen
HA Scheraga, JA Shafer, DL Higgins
Critical Reviews in Clinical Laboratory Sciences 1988
Isolation and characterization of two domains of human von Willebrand factor that interact with fibrillar collagen types I and III
FI Pareti, K Niiya, JM McPherson, ZM Ruggeri
The Journal of biological chemistry 1987
Structure of pre-pro-von Willebrand factor and its expression in heterologous cells
DT Bonthron, RI Handin, RJ Kaufman, LC Wasley, EC Orr, LM Mitsock, B Ewenstein, J Loscalzo, D Ginsburg, SH Orkin
Nature 1986
Localization of binding sites within human von Willebrand factor for monomeric type III collagen
GJ Roth, K Titani, LW Hoyer, MJ Hickey
Biochemistry 1986

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