Feedback regulation of pancreatic enzyme secretion occurs in rats. Whether such a system exists in man remains unsettled and the responsible mechanism is unknown. To investigate this question gastrointestinal intubation and perfusion were performed in 12 healthy subjects. Intraduodenal perfusion of trypsin-inhibited phenylalanine-, oleic acid-, and meal-stimulated chymotrypsin and lipase outputs in a dose-related manner. The minimal concentration of bovine trypsin needed to inhibit pancreatic enzyme secretion was 0.5 g/liter. 1 g/liter caused a maximal suppression of 35 +/- 4% of the phenylalanine-stimulated chymotrypsin release. This inhibitory effect was protease-specific. Intraduodenal perfusion of phenylalanine and oleic acid increased plasma cholecystokinin (CCK) from a basal level of 0.9 +/- 0.06 to 5.3 +/- 0.9 pM and 7.2 +/- 1.3 pM, respectively. Addition of bovine trypsin to the perfusates significantly reduced the plasma CCK level to basal values. This inhibitory effect of trypsin on CCK release was dose dependent and specific to proteases. Therefore, the present studies indicate that feedback regulation of pancreatic enzyme secretion is operative in man and it is mediated by release of CCK.
C Owyang, D S Louie, D Tatum
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Basal pancreatic secretion in a comparative aspect in poultry and rodents
Kuzmina IV, Tolpygo SM, Kotov AV, Shoibonov BB, Zamolodchikova TS |
Frontiers in physiology | 2024 |
Pancreatic Enzyme Use Reduces Pancreatitis Frequency in Children With Acute Recurrent or Chronic Pancreatitis: A Report From INSPPIRE.
Freeman AJ, Ng K, Wang F, Abu-El-Haija MA, Chugh A, Cress GA, Fishman DS, Gariepy CE, Giefer MJ, Goday P, Gonska TY, Grover AS, Lindblad D, Liu QY, Maqbool A, Mark JA, McFerron BA, Mehta MS, Morinville VD, Noel RA, Ooi CY, Perito ER, Schwarzenberg SJ, Sellers ZM, Wilschanski M, Zheng Y, Yuan Y, Andersen DK, Lowe ME, Uc A |
The American journal of gastroenterology | 2024 |
Clinical Pancreatology for Practising Gastroenterologists and Surgeons
JE DomínguezMuñoz |
2021 | |
Medical Management of Chronic Pancreatitis in Children: A Position Paper by the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Pancreas Committee
AJ Freeman, A Maqbool, MD Bellin, KR Goldschneider, AS Grover, C Hartzell, TL Piester, F Szabo, BD Kiernan, R Khalaf, R Kumar, M Rios, SZ Husain, VD Morinville, M Abu-El-Haija |
Journal of Pediatric Gastroenterology and Nutrition | 2021 |
Targeting obesity with plant-derived pancreatic lipase inhibitors: A comprehensive review
L Rajan, D Palaniswamy, SK Mohankumar |
Pharmacological research : the official journal of the Italian Pharmacological Society | 2020 |
Chronic Pancreatitis: Epidemiology, Diagnosis, and Management Updates
A Kichler, S Jang |
Drugs | 2020 |
Pancreatobiliary Diversion in the Mouse
X Chen, S Qiu, Q Li, L Hu, C Yao, X Xu, F Wang |
European Surgical Research | 2020 |
Therapeutic Enzymes: Function and Clinical Implications
N Labrou |
2019 | |
Therapeutic Enzymes: Function and Clinical Implications
N Labrou |
2019 | |
Therapeutic Enzymes: Function and Clinical Implications
N Labrou |
2019 | |
Therapeutic Enzymes: Function and Clinical Implications
N Labrou |
2019 | |
Therapeutic Enzymes: Function and Clinical Implications
N Labrou |
2019 | |
Therapeutic Enzymes: Function and Clinical Implications
N Labrou |
2019 | |
Therapeutic Enzymes: Function and Clinical Implications
N Labrou |
2019 | |
Plasmid DNA nicking- a Novel Activity of Soybean Trypsin Inhibitor and Bovine Aprotinin
MR Islam, K Ihenacho, JW Park, IS Islam |
Scientific Reports | 2019 |
Identification and characterization of a calcium dependent bacillopeptidase from Bacillus subtilis CFR5 with novel kunitz trypsin inhibitor degradation activity
GR Sharmila, PM Halami, G Venkateswaran |
Food research international (Ottawa, Ont.) | 2018 |
The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery
HG Beger, AL Warshaw, RH Hruban, MW Büchler, MM Lerch, JP Neoptolemos, T Shimosegawa, DC Whitcomb, C Groß |
2018 | |
Inhibition effect of food preservatives on endoproteinases
EN Esimbekova, AA Asanova, AA Deeva, VA Kratasyuk |
Food Chemistry | 2017 |
Guidelines for the understanding and management of pain in chronic pancreatitis
AM Drewes, SA Bouwense, CM Campbell, GO Ceyhan, M Delhaye, IE Demir, PK Garg, H Goor, C Halloran, S Isaji, JP Neoptolemos, SS Olesen, T Palermo, PJ Pasricha, A Sheel, T Shimosegawa, E Szigethy, DC Whitcomb, D Yadav |
Pancreatology | 2017 |
Management of pain in chronic pancreatitis with emphasis on exogenous pancreatic enzymes
PM Hobbs, WG Johnson, DY Graham |
World journal of gastrointestinal pharmacology and therapeutics | 2016 |
Hawthorn Nectar Enhances Gastrointestinal Motility as Well as Stimulates Intestinal Am-ylase and Lipase Activities in Mice
S Zou, J Li, C Ma, J Chen, PK Leong, HY Leung, WM Chan, HS Wong, KM Ko |
Chinese medicine | 2015 |
Yamada' s Textbook of Gastroenterology
DK Podolsky, M Camilleri, JG Fitz, AN Kalloo, F Shanahan, TC Wang |
Yamada' s Textbook of Gastroenterology | 2015 |
Comprehensive Physiology
SN Cheuvront, RW Kenefick |
Comprehensive Physiology | 2014 |
Modern Treatment of Patients with Chronic Pancreatitis
G Trikudanathan, U Navaneethan, SS Vege |
Gastroenterology Clinics of North America | 2012 |
Regulation of pancreatic exocrine secretion in goats: differential effects of short- and long-term duodenal phenylalanine treatment : Phenylalanine affects pancreatic exocrine secretion of goats
ZP Yu, M Xu, JH Yao, K Liu, F Li, Y Liu, F Wang, FF Sun, NN Liu |
Journal of Animal Physiology and Animal Nutrition | 2012 |
The Exocrine Pancreas
SJ Pandol |
Colloquium Series on Integrated Systems Physiology: From Molecule to Function | 2011 |
Amino acids stimulate cholecystokinin release through the Ca 2+ -sensing receptor
Y Wang, R Chandra, LA Samsa, B Gooch, BE Fee, JM Cook, SR Vigna, AO Grant, RA Liddle |
AJP Gastrointestinal and Liver Physiology | 2011 |
Physiological parameters governing the action of pancreatic lipase
IA Brownlee, DJ Forster, MD Wilcox, PW Dettmar, CJ Seal, JP Pearson |
Nutrition Research Reviews | 2010 |
Hormones, Brain and Behavior
J Bernal |
Hormones, Brain and Behavior | 2009 |
Microbiota-triggered colonic delivery: Robustness of the polysaccharide approach in the fed state in man
AW Basit, MD Short, EL McConnell |
Journal of Drug Targeting | 2009 |
Negative Control of Human Pancreatic Secretion
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Pancreas | 2008 |
Pain management in chronic pancreatitis
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World journal of gastroenterology : WJG | 2008 |
Ileal exposure to pig pancreatic juice and bile inhibit exocrine pancreatic secretion in pigs
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Livestock Science | 2007 |
Postprandial Gastrointestinal Hormone Production Is Different, Depending on the Type of Reconstruction Following Total Gastrectomy
K Kalmár, J Németh, D Kelemen, A Kelemen, E Agoston, OP Horváth |
Annals of Surgery | 2006 |
Role of cholecystokinin in the gastric motor response to a meal in horses
M Lorenzo-Figueras, AM Merritt |
American Journal of Veterinary Research | 2006 |
Biochemistry and Biology of SPINK-PSTI and Monitor Peptide
R Graf, D Bimmler |
Endocrinology and metabolism clinics of North America | 2006 |
Human pancreatic exocrine response to nutrients in health and disease
J Keller, P Layer |
Gut | 2005 |
Fisiopatología, diagnóstico y tratamiento de la insuficiencia pancreática exocrina tras pancreatitis aguda
JM Sempere, M Pérez-Mateo |
Gastroenterología y Hepatología | 2005 |
Pancreatitis: Advances in Pathobiology, Diagnosis and Treatment
RW Ammann, G Adler, MW Büchler, EP DiMagno, M Sarner |
2005 | |
Encyclopedia of Endocrine Diseases
J Borén, O Wiklund |
Encyclopedia of Endocrine Diseases | 2004 |
Tropical chronic pancreatitis
KK Barman, G Premalatha, V Mohan |
Postgraduate medical journal | 2003 |
Encyclopedia of Hormones
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Inhibition of endogenous pancreatic enzyme secretion by oral pancreatic enzyme treatment
J Walkowiak, H Witmanowski, K Strzykala, B Bychowiec, T Songin, K Borski, KH Herzig |
European Journal of Clinical Investigation | 2003 |
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RM Mitchell, MF Byrne, J Baillie |
The Lancet | 2003 |
Development of the Pancreas and Small Intestine in Rat
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The Showa University Journal of Medical Sciences | 2003 |
Differential mechanism and site of action of CCK on the pancreatic secretion and growth in rats
M Yamamoto, M Otani, DM Jia, KI Fukumitsu, H Yoshikawa, T Akiyama, M Otsuki |
AJP Gastrointestinal and Liver Physiology | 2003 |
Clinical Evaluation of Oral Administration of a Cholecystokinin-A Receptor Antagonist (Loxiglumide) to Patients with Acute, Painful Attacks of Chronic Pancreatitis: A Multicenter Dose–Response Study in Japan
K Shiratori, T Takeuchi, K Satake, S Matsuno |
Pancreas | 2002 |
Conservative treatment of chronic pancreatitis
A Khalid, DC Whitcomb |
European Journal of Gastroenterology & Hepatology | 2002 |
Chronic pancreatitis: Asia-Pacific consensus report
RK Tandon, N Sato, PK Garg |
Journal of Gastroenterology and Hepatology | 2002 |
Persistent decreased plasma cholecystokinin levels in celiac patients under gluten-free diet: respective roles of histological changes and nutrient hydrolysis
P Deprez, C Sempoux, BE van Beers, A Jouret, A Robert, J Rahier, A Geubel, S Pauwels, P Mainguet |
Regulatory Peptides | 2002 |
Pathological evaluation, clinical chemistry and plasma cholecystokinin in neonatal and young miniature swine fed soy trypsin inhibitor from 1 to 39 weeks of age
LH Garthoff, GR Henderson, AO Sager, TJ Sobotka, DW Gaines, MW O'Donnell, R Chi, SJ Chirtel, CN Barton, LH Brown, FA Hines, T Solomon, J Turkleson, D Berry, H Dick, F Wilson, MA Khan |
Food and Chemical Toxicology | 2002 |
Biliary acute pancreatitis:a review
Osvaldo M Tiscornia, Susana Hamamura, Enriqueta S Lehmann, Graciela Otero, Hipolito Waisman, Patricia Tiscornia-Wasserman, Simmy Bank |
World journal of gastroenterology : WJG | 2002 |
Luminal CCK-releasing factor stimulates CCK release from human intestinal endocrine and STC-1 cells
Y Wang, V Prpic, GM Green, JR Reeve, RA Liddle |
AJP Gastrointestinal and Liver Physiology | 2002 |
Pancreatic enzyme replacement therapy
L Peter, K Jutta, PG Lankisch |
Current Gastroenterology Reports | 2001 |
Feedback control of pancreatic exocrine secretion: its relationship to the management of the abdominal pain associated with chronic pancreatitis
PP Toskes |
Transactions of the American Clinical and Climatological Association | 2001 |
Diazepam-binding inhibitor mediates feedback regulation of pancreatic secretion and postprandial release of cholecystokinin
Y Li, Y Hao, C Owyang |
Journal of Clinical Investigation | 2000 |
Pathophysiological role of cholecystokinin in humans
M Otsuki |
Journal of Gastroenterology and Hepatology | 2000 |
Adaptation of the exocrine pancreas to dietary fats
MD Yago, E Martínez-Victoria, RJ Díaz, MA Martínez, J Singh, M Mañas |
Journal of Physiology and Biochemistry | 2000 |
A secretin releasing peptide exists in dog pancreatic juice
P Li, Y Song, KY Lee, TM Chang, WY Chey |
Life Sciences | 2000 |
Biliary acute pancreatitis: A review
Osvaldo M. Tiscornia, Susana Hamamura, Enriqueta S. de Lehmann, Graciela Otero, Hipólito Waisman, Patricia Tiscornia-Wasserman, Simmy Bank |
World journal of gastroenterology : WJG | 2000 |
Pathogenesis and managenent of pain in chronic pancreatitis
C.S.Pitchumoni |
World journal of gastroenterology : WJG | 2000 |
Cellular mechanism of sodium oleate-stimulated secretion of cholecystokinin and secretin
CH Chang, WY Chey, TM Chang |
AJP Gastrointestinal and Liver Physiology | 2000 |
Effects of Intraluminal Trypsin and Bile on the Exocrine and Endocrine Pancreas After Pancreaticobiliary Diversion and Biliodigestive Shunt:
B Ohlsson, T Yusa, JF Rehfeld, I Lundquist, I Ihse, J Axelson |
Pancreas | 2000 |
Drug Development
TS Gaginella, A Guglietta |
2000 | |
Assessment of Pancreatic Enzyme Secretory Capacity by a Modified Lundh Test
L Czakó, F Hajnal, J Németh, J Lonovics |
International Journal of Gastrointestinal Cancer | 2000 |
Pathogenesis and managenent of pain in chronic pancreatitis.
Pitchumoni CS |
World Journal of Gastroenterology | 2000 |
Pancreatic Enzymes: Secretion and Luminal Nutrient Digestion in Health and Disease
P Layer, J Keller |
Journal of Clinical Gastroenterology | 1999 |
Chronic Pancreatitis: Complications and Management
MV Apte, GW Keogh, JS Wilson |
Journal of Clinical Gastroenterology | 1999 |
Pain Management in chronic pancreatitis
DL Conwell, G Zuccaro |
Current Treatment Options in Gastroenterology | 1999 |
ENZYMATIC THERAPY IN PATIENTS WITH CHRONIC PANCREATITIS
NJ Greenberger |
Gastroenterology Clinics of North America | 1999 |
PALLIATION OF PAIN IN CHRONIC PANCREATITIS
J Mössner |
Surgical Clinics of North America | 1999 |
Inhibition of digestive proteases by vegetable meals in three fish species; seabream (Sparus aurata), tilapia (Oreochromis niloticus) and African sole (Solea senegalensis)
FJ López, IM Dı́az, MD López, FJ López |
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology | 1999 |
Radiology of the Pancreas
AL Baert, G Delorme, LV Hoe |
1999 | |
Darmkrankheiten
WF Caspary, J Stein |
1999 | |
Adaptation of the human pancreas to inhibition of luminal proteolytic activity
H Friess, J Kleeff, R Isenmann, P Malfertheiner, MW Büchler |
Gastroenterology | 1998 |
Regulation of the action of the novel cholecystokinin-releasing peptide diazepam binding inhibitor by inhibitory hormones and taurocholate
KH Herzig, C Wilgus, I Schön, K Tatemoto, UR Fölsch |
Regulatory Peptides | 1998 |
Chronic Pancreatitis
CS Pitchumoni |
Journal of Clinical Gastroenterology | 1998 |
AGA technical review: Treatment of pain in chronic pancreatitis
AL Warshaw, PA Banks, CF Castillo |
Gastroenterology | 1998 |
Involvement of Endogenous Cholecystokinin and Somatostatin in Gastroprotection Induced by Intraduodenal Fat
T Brzozowski, PC Konturek, SJ Konturek, S Kwiecień, R Pajdo, I Brzozowska, EG Hahn |
Journal of Clinical Gastroenterology | 1998 |
CCK-, secretin-, and cholinergic-independent pancreatic fluid hypersecretion in protease inhibitor-treated rats
M Yamamoto, H Shirohara, M Otsuki |
AJP Gastrointestinal and Liver Physiology | 1998 |
Influence of High-Dose Pancreatic Enzyme Treatment on Pancreatic Function in Healthy Volunteers
H Friess, J Kleeff, P Malfertheiner, MW Müller, K Homuth, MW Büchler |
International Journal of Gastrointestinal Cancer | 1998 |
Cholecystokinin-A receptor antagonists: therapies for gastrointestinal disorders
M D'Amato, LC Rovati |
Expert Opinion on Investigational Drugs | 1997 |
CHOLECYSTOKININ CELLS
RA Liddle |
Annual Review of Physiology | 1997 |
The potency of dietary amino acids in elevating plasma cholecystokinin immunoreactivity in cats is related to amino acid hydrophobicity
RC Backus, KA Howard, QR Rogers |
Regulatory Peptides | 1997 |
Plasma cholecystokinin and its precursors in hepatic cirrhosis
LI Paloheimo, O Clemmesen, K Dalhoff, JF Rehfeld |
Journal of Hepatology | 1997 |
Clinical Studies of Human Pancreatic Enzyme Synthesis
SJ O'Keefe |
The Yale journal of biology and medicine | 1997 |
Plasma Concentrations of Cholecystokinin and Neurotensin in Patients with Cystic Fibrosis
KH Herzig, J Domagk, R Nustede, M Stern, B Bewig, WK Cichy, UR Fölsch |
Scandinavian Journal of Gastroenterology | 1997 |
Feedback Regulation of Pancreatic Exocrine Secretion in Minipigs
T Houe, SS Sætre, P Svendsen, O Olsen, JF Rehfeld, OB de Muckadell |
Scandinavian Journal of Gastroenterology | 1997 |
Distribution and Localization of a Novel Cholecystokinin-Releasing Factor in the Rat Gastrointestinal Tract*
N Tarasova, AW Spannagel, GM Green, G Gomez, JT Reed, JC Thompson, MR Hellmich, JR Reeve, RA Liddle, GH Greeley |
Endocrinology | 1997 |
Clinical Pathology of Pancreatic Disorders
JA Lott |
1997 | |
Diagnostic Procedures in Pancreatic Disease
P Malfertheiner, JE Domínguez-Muñoz, HU Schulz, H Lippert |
1997 | |
Purification and characterization of a luminal cholecystokinin-releasing factor from rat intestinal secretion
AW Spannagel, GM Green, D Guan, RA Liddle, K Faull, JR Reeve |
Proceedings of the National Academy of Sciences | 1996 |
Effects of intravenous infusion of amino acids on cholecystokinin release and gallbladder contraction in humans
H Shirohara, A Tabaru, M Otsuki |
Journal of Gastroenterology | 1996 |
Effects of nafamostat mesilate, somatostatin, and glucagon on caerulein-induced acute pancreatitis in rats
K Mori, Y Marugami, Y Sakurai, M Ochiai, S Hasegawa, H Imazu, T Matsubara, M Suganuma, A Shikata, T Funabiki |
Journal of Hepato-Biliary-Pancreatic Surgery | 1996 |
Chronic Bile Diversion to the Urinary Bladder Enhances Cholecystokinin Release and Suppresses Gastric Inhibitory Polypeptide Release in Dogs
M Takahashi, I Sasaki, H Naito, Y Funayama, C Shibata, S Matsuno |
The Tohoku Journal of Experimental Medicine | 1996 |
Bile-pancreatic juice replacement not cholinergic-and cholecystokinin-receptor blockade reverses acinar cell hyperstimulation after bile-pancreatic duct ligation
I Samuel, RJ Joehl |
The American Journal of Surgery | 1996 |
Adaptation to high-fat diets: effects on eating behaviour and plasma cholecystokinin
SJ French, B Murray, RD Rumsey, R Fadzlin, NW Read |
British Journal of Nutrition | 1995 |
Decreased plasma levels of cholecystokinin in healthy males after chronic ingestion of a heat-treated soya product
LJ Lu, KE Anderson, G Gomez, WH Nealon |
Cancer Letters | 1995 |
No Effect of Long-Term Treatment with Pancreatic Extract on Recurrent Abdominal Pain in Patients with Chronic Pancreatitis
A Malesci, E Gaia, A Fioretta, P Bocchia, G Ciravegna, P Cantor, I Vantini |
Scandinavian Journal of Gastroenterology | 1995 |
Pain in Chronic Pancreatitis
JB Jansen, JH Kuijpers, FJ Zitman, R Dongen |
Scandinavian Journal of Gastroenterology | 1995 |
Effect of predigested fat on intestinal stimulation of plasma cholecystokinin and gall bladder motility in coeliac disease
WP Hopman, G Rosenbusch, MP Hectors, JB Jansen |
Gut | 1995 |
Profound duodenogastric reflux causes pancreatic growth in rats
T Gasslander, H Mukaida, MK Herrington, RA Hinder, TE Adrian |
Gut | 1995 |
Chirurgisches Forum ’95 für experimentelle und klinische Forschung
HG Beger, G Hierholzer, J Seifert, W Hartel |
1995 | |
On the role of cholecystokinin in pancreatic cancer
MK Herrington, TE Adrian |
International Journal of Gastrointestinal Cancer | 1995 |
Time-course of the pancreatic changes following long-term stimulation or inhibition of the CCK-A receptor
B Ohlsson, J Axelson, B Sternby, JF Rehfeld, I Ihse |
International Journal of Gastrointestinal Cancer | 1995 |
No negative feedback regulation between plasma CCK levels and luminal tryptic activities in patients with pancreatic insufficiency
T Nakamura, K Takebe, K Kudoh, M Ishii, K Imamura, H Kikuchi, F Kasai, Y Tandoh, N Yamada, Y Arai, A Terada, K Machida |
International Journal of Gastrointestinal Cancer | 1995 |
Feedback Inhibition of Cholecystokinin Secretion by Bile Acids and Pancreatic Proteases
GM Green |
Annals of the New York Academy of Sciences | 1994 |
Biological actions of cholecystokinin
JN Crawley, RL Corwin |
Peptides | 1994 |
Regulation of Cholecystokinin Gene Expression in Rat Intestine
RA Liddle |
Annals of the New York Academy of Sciences | 1994 |
Relationship between postprandial release of CCK and PP in health and in chronic pancreatitis
B Glasbrenner, JE Dominguez-Muñoz, DK Nelson, RL Riepl, M Büchler, P Malfertheiner |
Regulatory Peptides | 1994 |
Effect of bile salt binding or protease inactivation on plasma cholecystokinin and gallbladder responses to bombesin
PW Thimister, WP Hopman, CE Sloots, G Rosenbusch, A Tangerman, HL Willems, CB Lamers, JB Jansen |
Gastroenterology | 1994 |
Roles of gut hormones in negative-feedback regulation of pancreatic exocrine secretion in humans
HO Jin, CW Song, TM Chang, WY Chey |
Gastroenterology | 1994 |
Endogenous cholecystokinin stimulates pancreatic enzyme secretion via vagal afferent pathway in rats
Y Li, C Owyang |
Gastroenterology | 1994 |
Facing the Pancreatic Dilemma
P Pederzoli, G Cavallini, C Bassi, M Falconi |
1994 | |
Pancreatic enzymes in chronic pancreatitis
P Layer, G Holtmann |
International Journal of Gastrointestinal Cancer | 1994 |
Gastrin-releasing peptide and CCK after intraduodenal inhibition of proteases in dogs
R Nustede, WE Schmidt, M Jäger, F Stöckmann, H Köhler, UR Fölsch, HJ Peiper |
International Journal of Gastrointestinal Cancer | 1994 |
Effect of jejunal infusion of different caloric loads on pancreatic enzyme secretion and gastro-intestinal hormone response in man
A Pfeiffer, N Vidon, GE Feurle, JA Chayvialle, JJ Bernier |
European Journal of Clinical Investigation | 1993 |
Effect of duodenal juice on bombesin-stimulated cholecystokinin release during loxigIumide administration in man
MC Jebbink, JB Jansen, FG van der Kleij, DM Mooy, LC Rovatit, CB Lamers |
European Journal of Clinical Investigation | 1993 |
Endogenous somatostatin possibly controls pancreatic growth: Further evidence for feedback regulation
M Rünzi, MK Müller, H Goebell |
Regulatory Peptides | 1993 |
Role of secretin in negative feedback regulation of postprandial pancreatic secretion in dogs
M Imamura, KY Lee, Y Song, M Moriyasu, TM Chang, WY Chey |
Gastroenterology | 1993 |
Standards in Pancreatic Surgery
HG Beger, M Büchler, P Malfertheiner |
1993 | |
Ökosystem Darm V
M Zeitz, WF Caspary, J Bockemühl, G Lux |
1993 | |
Duodenal juice total protein and pancreatic enzyme synthesis, turnover, and secretion in patients after acute pancreatitis
JM Ogden, SJ O'Keefe, JA Louw, G Adams, IN Marks |
Gut | 1993 |
Ökosystem Darm IV
J Bockemühl, R Ottenjann, M Zeitz, G Lux |
1993 | |
The influence of bile acids on the regulation of exocrine pancreatic secretion and on the plasma concentrations of neurotensin and CCK in dogs
R Nustede, WE Schmidt, H Köhler, UR Fölsch, A Schafmayer |
International Journal of Gastrointestinal Cancer | 1993 |
Cholecystokinin cells purified by fluorescence-activated cell sorting respond to monitor peptide with an increase in intracellular calcium
RA Liddle, MA Misukonis, L Pacy, AE Balber |
Proceedings of the National Academy of Sciences | 1992 |
Trypsin inhibitor and maternal reunion increase plasma cholecystokinin in neonatal rats
A Weller, ES Corp, A Tyrka, RC Ritter, L Brenner, J Gibbs, GP Smith |
Peptides | 1992 |
Evidence against autocrine feedback regulation of cholecystokinin secretion in man
MC Jebbink, JB Jansen, DM Mooy, CM Schouten, CB Lamers |
Peptides | 1992 |
Effect of chymotrypsin on human cholecystokinin release: use of clostripain in the validation of a new radioimmunoassay
K Beardshall, P Deprez, RJ Playford, M Alexander, J Calam |
Regulatory Peptides | 1992 |
Influence of dietary protein concentrations or of duodenal amino acid infusion on cholecystokinin release in goats
M Furuse, M Kato, SI Yang, K Asakura, J Okumura |
Comparative Biochemistry and Physiology Part A: Physiology | 1992 |
The effect of the cholecystokinin receptor antagonist MK-329 on meal-stimulated pancreaticobiliary output in humans
P Cantor, PE Mortensen, J Myhre, I Gjorup, H Worning, E Stahl, TT Survill |
Gastroenterology | 1992 |
A New Twist in the Brain-Gut Axis
DC Whitcomb, IL Taylor |
The American Journal of the Medical Sciences | 1992 |
Pancreatic Fistulas
P Pederzoli, C Bassi, S Vesentini |
1992 | |
Cholecystokinin receptor antagonist loxiglumide modulates plasma levels of gastro-entero-pancreatic hormones in man Feedback control of cholecystokinin and gastrin secretion
WE Schmidt, W Creutzfeldt, M Höcker, R Nustede, AR Choudhury, A Schleser, LC Rovati, UR Fölsch |
European Journal of Clinical Investigation | 1991 |
A note on plasma cholecystokinin concentration in dairy cows
M Furuse, SI Yang, YH Choi, N Kawamura, A Takahashi, J Okumura |
Animal Production | 1991 |
The importance of gastric secretion in the feedback control of interdigestive and postprandial pancreatic secretion in rats
SJ Konturek, E Krzyzek, J Bilski |
Regulatory Peptides | 1991 |
Factors Influencing the Release of Cholecystokinin Induced by Gastrin-Releasing Peptide in Man
L Lundell, P Cantor, M Sjövall, JF Rehfeld, L Olbe |
Scandinavian Journal of Gastroenterology | 1991 |
Pancreatic Enzymes in Health and Disease
PG Lankisch |
1991 | |
Regulation of pancreatic exocrine secretion
WY Chey |
International Journal of Gastrointestinal Cancer | 1991 |
Perspectives of CCK antagonists in pancreatic research: Part II. Experimental studies
T Takács, Á Pap |
International Journal of Gastrointestinal Cancer | 1991 |
Perspectives of CCK antagonists in pancreatic research and clinical use: Part I
LC Rovati |
International Journal of Gastrointestinal Cancer | 1991 |
Is there a duodenum-pancreas negative feedback?: Views: Pro and con
DF Magee |
International Journal of Gastrointestinal Cancer | 1991 |
Interactions of pancreatic secretory trypsin inhibitor in small intestinal juice: Its hydrolysis and protection by intraluminal factors
TC Freeman, R Davies, J Calam |
Clinica Chimica Acta | 1990 |
Oral administration of proteinase inhibitor II from potatoes reduces energy intake in man
AJ Hill, SR Peikin, CA Ryan, JE Blundell |
Physiology & Behavior | 1990 |
Feedback regulation of pancreatic exocrine secretion in animal and man
UR Fölsch |
European Journal of Clinical Investigation | 1990 |
Gastrointestinal Endocrinology
CC Wang, YH Tu, WY Zhu |
Gastrointestinal Endocrinology | 1990 |
Role of Cholecystokinin in the Regulation of Pancreatic Enzyme Secretion in the Rat
AJ de Jong, JB Jansen, CB Lamers |
Scandinavian Journal of Gastroenterology | 1990 |
Enhanced Release of Cholecystokinin by Soya-Bean Trypsin Inhibitor in Chickens
M Furuse, SI Yang, T Muramatsu, J Okumura |
Scandinavian Journal of Gastroenterology | 1990 |
Feedback Regulation of Human Pancreatic Secretion
P Layer, JB Jansen, L Cherian, CB Lamers, H Goebell |
Gastroenterology | 1990 |
Effect of pancreatic proteases on plasma cholecystokinin, secretin, and pancreatic exocrine secretion in response to sodium oleate
P Li, KY Lee, XS Ren, TM Chang, WY Chey |
Gastroenterology | 1990 |
Effect of partial gastrectomy with Billroth II or Roux-en-Y anastomosis on postprandial and cholecystokinin-stimulated gallbladder contraction and secretion of cholecystokinin and pancreatic polypeptide
PN Rieu, JB Jansen, WP Hopman, HJ Joosten, CB Lamers |
Digestive Diseases and Sciences | 1990 |
Hyperlipidemic Pancreatitis
PP Toskes |
Gastroenterology Clinics of North America | 1990 |
A critical appraisal of studies of the pancreas: Animal models used in pancreas research: Studies on feedback regulations of the pancreas
B Göke |
International Journal of Gastrointestinal Cancer | 1990 |
Effects of a novel cholecystokinin (CCK) receptor antagonist, MK-329, on gallbladder contraction and gastric emptying in humans. Implications for the physiology of CCK
RA Liddle, BJ Gertz, S Kanayama, L Beccaria, LD Coker, TA Turnbull, ET Morita |
Journal of Clinical Investigation | 1989 |
Endogenous cholecystokinin regulates growth of human cholangiocarcinoma
BM Evers, G Gomez, CM Townsend, S Rajaraman, JC Thompson |
Annals of Surgery | 1989 |
Down-regulation of pancreatic growth and gallbladder contractility by bile salts
G Gomez, CM Townsend, R Maani, P Singh, GG Greeley, JC Thompson |
The American Journal of Surgery | 1989 |
Effect of pancreatic enzyme supplementation on postprandial plasma cholecystokinin secretion in patients with pancreatic insufficiency
JB Jansen, MC Jebbink, HJ Mulders, CB Lamers |
Regulatory Peptides | 1989 |
Enhanced release of cholecystokinin by dietary amino acids in chicks (Gallus domesticus)
SI Yang, F Mitsuhiro, M Tatsuo, O Jun-Ichi |
Comparative Biochemistry and Physiology Part A: Physiology | 1989 |
Responses of the pancreatic digestive enzyme secretion to various combinations of amino acids and cholecystokinin in chicks (Gallus domesticus)
SI Yang, F Mitsuhiro, M Tatsuo, O Jun-Ichi |
Comparative Biochemistry and Physiology Part A: Physiology | 1989 |
Pancreatic Secretion and the Release of Cholecystokinin after a Meal in Dogs with and without Exclusion of Pancreatic Juice
M Kogire, K Inoue, R Hosotani, YS Huang, JC Thompson, T Tobe |
Scandinavian Journal of Gastroenterology | 1989 |
Differential effects of atropine and a cholecystokinin receptor antagonist on pancreatic secretion
G Adler, M Reinshagen, I Koop, B Göke, A Schafmayer, LC Rovati, R Arnold |
Gastroenterology | 1989 |
Effect of pancreatic juice diversion on secretin release in rats
G Sun, KY Lee, TM Chang, WY Chey |
Gastroenterology | 1989 |
Effect of Pancreatic juice and Trypsin on Oleic Acid-Stimulated Pancreatic Secretion and Plasma Secretin in Dogs
K Shiratori, YH Jo, KY Lee, TM Chang, WY Chey |
Gastroenterology | 1989 |
Influence of treatment with pancreatic extracts on pancreatic enzyme secretion
J Mossner, HP Wresky, W Kestel, J Zeeh, U Regner, W Fischbach |
Gut | 1989 |
Integrated Actions of Cholecystokinin on the Gastrointestinal Tract: Use of the Cholecystokinin Bioassay
RA Liddle |
Gastroenterology Clinics of North America | 1989 |
Gastrointestinal Peptides
DW Green, G Gomez, GH Greeley |
Gastroenterology Clinics of North America | 1989 |
Feedback regulation of stimulated pancreatic enzyme secretion during intraduodenal perfusion of trypsin in man
J Dlugosz, UR Fölsch, A Czajkowski, A Gabryelewicz |
European Journal of Clinical Investigation | 1988 |
Stimulation of pancreatic secretion in man by a protease inhibitor (camostate)
G Adler, A Müllenhoff, I Koop, T Bozkurt, B Göke, C Beglinger, R Arnold |
European Journal of Clinical Investigation | 1988 |
Participation of gastric mechanoreceptors and intestinal chemoreceptors in the gastrocolonic response
J Wiley, D Tatum, R Keinath, C Owyang |
Gastroenterology | 1988 |
Regulation of the release of cholecystokinin by bile salts in dogs and humans
G Gomez, JR Upp, F Lluis, RW Alexander, GJ Poston, GH Greeley, JC Thompson |
Gastroenterology | 1988 |
Temporal relationships of cholecystokinin release, pancreatobiliary secretion, and gastric emptying of a mixed meal
M Fried, EA Mayer, JB Jansen, CB Lamers, IL Taylor, SR Bloom, JH Meyer |
Gastroenterology | 1988 |
Pancreatic secretory response to ordinary meals: Studies with pure pancreatic juice
L Gullo, P Priori, R Pezzilli, G Biliotti, G Mattioli, L Barbara |
Gastroenterology | 1988 |
Effect of Trypsin on the Hormonal Regulation of the Fat-Stimulated Human Exocrine Pancreas
O Olsen, OB de Muckadell, P Cantor, C Erlanson-Albertsson, CP Hansen, H Worning |
Scandinavian Journal of Gastroenterology | 1988 |
Plasma CCK levels in patients with pancreatic insufficiency
T Bozkurt, G Adler, I Koop, H Koop, W Trmer, R Arnold |
Digestive Diseases and Sciences | 1988 |
Lack of insulinotropic effect of endogenous and exogenous cholecystokinin in man
J Reimers, M Nauck, W Creutzfeldt, J Strietzel, R Ebert, P Cantor, G Hoffmann |
Diabetologia | 1988 |
Raw soya-bean flour increases cholecystokinin release in man
J Calam, JC Bojarski, CJ Springer |
British Journal of Nutrition | 1987 |
Trypsin suppression of pancreatic enzyme secretion
C Owyang, D May, DS Louie |
Gastroenterology | 1986 |
Pancreatic Disease
EC Kafka, MH Kalser |
Postgraduate Medicine | 1975 |
Advances in Metabolic Disorders
G Aurbach, JT Potts |
Advances in Metabolic Disorders | 1964 |