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Beta-2 microglobulin is an amyloidogenic protein in man.

P D Gorevic, … , F C Prelli, B Frangione

P D Gorevic, … , F C Prelli, B Frangione

Published December 1, 1985
Citation Information: J Clin Invest. 1985;76(6):2425-2429. https://doi.org/10.1172/JCI112257.

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Citations to this article (206)

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The residues 4 to 6 at the N-terminus in particular modulate fibril propagation of β-microglobulin. Dang H, Chen Z, Chen W, Luo X, Liu P, Wang L, Chen J, Tang X, Wang Z, Liang Y	Acta Biochimica et Biophysica Sinica	2022
Beta-2-Microglobulin is an Independent Risk Factor for Asymptomatic Carotid Atherosclerosis in Patients with Primary Aldosteronism S Liang, Q Li, Q Lai, Y Zhou, H Zhang, X Chen, B Yao, W Xu, X Yang	Journal of Atherosclerosis and Thrombosis	2021
Mass spectrometry of urinary β2 microglobulin oligomer in patients with proteinuria S Akizuki, K Kawano, T Iwamoto, K Nakada, A Ohnishi	Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy	2020
Investigating the Molecular Basis of the Aggregation Propensity of the Pathological D76N Mutant of Beta-2 Microglobulin: Role of the Denatured State L Visconti, F Malagrinò, L Broggini, CD Luca, F Moda, S Gianni, S Ricagno, A Toto	International journal of molecular sciences	2019
Positron Emission Tomography Can Support the Diagnosis of Dialysis-Related Amyloidosis G Santagati, E Cataldo, V Columbano, A Chatrenet, D Penna, E Pelosi, M Hachemi, L Gendrot, L Nielsen, F Cinquantini, P Saulnier, V Arena, C Boursot, GB Piccoli	Journal of Clinical Medicine	2019
An unusual case of Aβ2M amyloid deposition in bladder cancer in a non-dialysis patient: Aβ2M amyloid in non-dialysis patient A Ishii, Y Tei, T Murakami, K Notohara	Pathology International	2019
Biopolymer nanoparticle surface chemistry dictates the nature and extent of protein hard corona A Basu, S Kundu, C Basu, SK Ghosh, R Sur, A Mukherjee	Journal of Molecular Liquids	2019
In silico -guided identification of potential inhibitors against β 2 m aggregation in dialysis-related amyloidosis SS Narang, S Shuaib, D Goyal, B Goyal	Journal of Biomolecular Structure and Dynamics	2019
Persistent fever and destructive arthritis caused by dialysis-related amyloidosis: A case report K Matsumoto, J Kikuchi, Y Kaneko, H Yasuoka, K Suzuki, H Tokuyama, K Kameyama, K Yamaoka, T Takeuchi	Medicine	2018
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Chronic kidney disease, mineral bone disease and future risk of peripheral artery disease: Do associations rule? M Hecking, C Höbaus, GH Schernthaner	Atherosclerosis	2017
Systemic Amyloidosis: Lessons from β 2 -Microglobulin M Stoppini, V Bellotti	The Journal of biological chemistry	2015
Transthyretin-derived amyloidosis: Probably a common cause of lumbar spinal stenosis P Westermark, GT Westermark, OB Suhr, S Berg	Upsala Journal of Medical Sciences	2014
2-Microglobulin, Cystatin C, and Creatinine and Risk of Symptomatic Peripheral Artery Disease MM Joosten, JK Pai, ML Bertoia, RT Gansevoort, SJ Bakker, JP Cooke, EB Rimm, KJ Mukamal	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease	2014
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IR spectroscopic analyses of amyloid fibril formation of β2-microglobulin using a simplified procedure for its in vitro generation at neutral pH H Fabian, K Gast, M Laue, KJ Jetzschmann, D Naumann, A Ziegler, B Uchanska-Ziegler	Biophysical Chemistry	2013
Advances in ion mobility spectrometry–mass spectrometry reveal key insights into amyloid assembly☆ LA Woods, SE Radford, AE Ashcroft	Biochimica et Biophysica Acta	2013
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Protein Aggregation and Fibrillogenesis in Cerebral and Systemic Amyloid Disease JR Harris		2012
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Protein Aggregation and Fibrillogenesis in Cerebral and Systemic Amyloid Disease JR Harris		2012
Protein Aggregation and Fibrillogenesis in Cerebral and Systemic Amyloid Disease JR Harris		2012
Quantitative Analysis of Deamidation and Isomerization in β2-Microglobulin by 18 O Labeling M Fukuda, T Takao	Analytical Chemistry	2012
Removal of intact β2-microglobulin at neutral ph by using seed-conjugated polymer beads prepared with β2-microglobulin-derived peptide (58-67) S Kang, JE Yang, J Kim, M Ahn, HJ Koo, M Kim, YS Lee, SR Paik	Biotechnology Progress	2011
Characterization of the Response of Primary Cells Relevant to Dialysis-Related Amyloidosis to β2-Microglobulin Monomer and Fibrils MY Porter, KE Routledge, SE Radford, EW Hewitt	PloS one	2011
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Systemic amyloidosis: a challenge for the rheumatologist F Perfetto, A Moggi-Pignone, R Livi, A Tempestini, F Bergesio, M Matucci-Cerinic	Nature Reviews Rheumatology	2010
β2-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages C Liu, MR Sawaya, D Eisenberg	Nature Structural & Molecular Biology	2010
Mouse model to study human A β2M amyloidosis: generation of a transgenic mouse with excessive expression of human β2-microglobulin P Zhang, X Fu, J Sawashita, J Yao, B Zhang, J Qian, H Tomozawa, M Mori, Y Ando, H Naiki, K Higuchi	Amyloid	2010
Cardiac Amyloidosis HV Desai, WS Aronow, SJ Peterson, WH Frishman	Cardiology in Review	2010
Novel proteins associated with risk for coronary heart disease or stroke among postmenopausal women identified by in-depth plasma proteome profiling RL Prentice, S Paczesny, A Aragaki, LM Amon, L Chen, SJ Pitteri, M McIntosh, P Wang, TB Busald, J Hsia, RD Jackson, JE Rossouw, JE Manson, K Johnson, C Eaton, SM Hanash	Genome Medicine	2010
Glycosaminoglycans enhance the fibrillation propensity of the β2-microglobulin cleavage variant – ΔK58-β2m DB Corlin, CK Johnsen, MH Nissen, NH Heegaard	Biochemical and Biophysical Research Communications	2010
Pulmonary surfactant: an immunological perspective ZC Chroneos, Z Sever-Chroneos, VL Shepherd	Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology	2009
K3 Fragment of Amyloidogenic β2-Microglobulin Forms Ion Channels: Implication for Dialysis Related Amyloidosis M Mustata, R Capone, H Jang, FT Arce, S Ramachandran, R Lal, R Nussinov	Journal of the American Chemical Society	2009
Biomarkers of Alzheimer's disease R Craig-Schapiro, AM Fagan, DM Holtzman	Neurobiology of Disease	2009
β2-microglobulin: from physiology to amyloidosis NH Heegaard	Amyloid	2009
Nanobiotechnology for the Prevention of Dialysis-related Amyloidosis D Stamopoulos, P Bouziotis, D Benaki, PN Zirogiannis, K Kotsovassilis, V Belessi, V Dalamagas, K Papadopoulos	Therapeutic Apheresis and Dialysis	2009
Beta2-Microglobulin TB Drüeke, ZA Massy	Seminars in Dialysis	2009
Paget's Disease, Fibrous Dysplasia, Sarcoidosis, and Amyloidosis of Bone H Ilaslan, M Sundaram	Imaging of Arthritis and Metabolic Bone Disease	2009
A β2-microglobulin cleavage variant fibrillates at near-physiological pH DB Corlin, CK Johnsen, MH Nissen, NH Heegaard	Biochemical and Biophysical Research Communications	2009
Interactive sequences in the molecular chaperone, human αB crystallin modulate the fibrillation of amyloidogenic proteins JG Ghosh, SA Houck, JI Clark	The International Journal of Biochemistry & Cell Biology	2008
The influence of Cu2+ on the unfolding and refolding of intact and proteolytically processed β2-microglobulin ED Lorenzi, R Colombo, S Sabella, DB Corlin, NH Heegaard	Electrophoresis	2008
Utilization of nanobiotechnology in haemodialysis: mock-dialysis experiments on homocysteine D Stamopoulos, P Bouziotis, D Benaki, C Kotsovassilis, PN Zirogiannis	Nephrology Dialysis Transplantation	2008
Bare and protein-conjugated Fe3O4ferromagnetic nanoparticles for utilization in magnetically assisted hemodialysis: biocompatibility with human blood cells D Stamopoulos, E Manios, V Gogola, D Benaki, P Bouziotis, D Niarchos, M Pissas	Nanotechnology	2008
Early Stages of Misfolding and Association of β 2 -Microglobulin: Insights from Infrared Spectroscopy and Dynamic Light Scattering H Fabian, K Gast, M Laue, R Misselwitz, B Uchanska-Ziegler, A Ziegler, D Naumann	Biochemistry	2008
From the Cover: Nucleation of protein fibrillation by nanoparticles S Linse, C Cabaleiro-Lago, WF Xue, I Lynch, S Lindman, E Thulin, SE Radford, KA Dawson	Proceedings of the National Academy of Sciences	2007
Mass spectrometric characterization of conformational preludes to β2-microglobulin aggregation TJ Jørgensen, L Cheng, NH Heegaard	International Journal of Mass Spectrometry	2007
New Ligand Coupling Procedure for Formation of an Immunoadsorption Wall TH Yang, CL Feng	ASAIO Journal	2007
In vitro utilization of ferromagnetic nanoparticles in hemodialysis therapy D Stamopoulos, D Benaki, P Bouziotis, PN Zirogiannis	Nanotechnology	2007
Related disorders of bone FL Weng, S Goldfarb	Clinical Reviews in Bone and Mineral Metabolism	2007
Dialysis-related amyloidosis of the hip joints in long-term hemodialysis patients-MRI findings of hip joints in twelve female hemodialysis patients- H Suzuki, A Shibuya, T Akiba, K Nitta, M Ando	Nihon Toseki Igakkai Zasshi	2007
Protein Misfolding, Aggregation, and Conformational Diseases VN Uversky, AL Fink		2007
Variants of β2-microglobulin cleaved at lysine-58 retain the main conformational features of the native protein but are more conformationally heterogeneous and unstable at physiological temperature MC Mimmi, TJ Jørgensen, F Pettirossi, A Corazza, P Viglino, G Esposito, ED Lorenzi, S Giorgetti, M Pries, DB Corlin, MH Nissen, NH Heegaard	FEBS Journal	2006
Gastrointestinal β2microglobulin amyloidosis in hemodialysis patients: biochemical analysis of amyloid proteins in small formalin-fixed paraffin-embedded tissue specimens B Kaplan, BM Martin, A Livoff, D Yeremenko, A Livneh, HI Cohen	Modern Pathology	2005
Assessment of the Stability of an Immunoadsorbent for the Extracorporeal Removal of Beta-2-Microglobulin from Blood CM Daniels, EM Woolverton, SM Sprague, GA Ameer	Blood Purification	2005
Proteomics of β2-microglobulin amyloid fibrils M Stoppini, P Mangione, M Monti, S Giorgetti, L Marchese, P Arcidiaco, L Verga, S Segagni, P Pucci, G Merlini, V Bellotti	Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics	2005
Interactions of charged ligands with β2-microglobulin conformers in affinity capillary electrophoresis NH Heegaard, ED Lorenzi	Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics	2005
Towards an understanding of the structural molecular mechanism of β2-microglobulin amyloid formation in vitro SE Radford, WS Gosal, GW Platt	Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics	2005
Quantification of Cleaved β2-Microglobulin in Serum from Patients Undergoing Chronic Hemodialysis DB Corlin, JW Sen, S Ladefoged, GB Lund, MH Nissen, NH Heegaard	Clinical chemistry	2005
Co-populated Conformational Ensembles of β 2 -Microglobulin Uncovered Quantitatively by Electrospray Ionization Mass Spectrometry AJ Borysik, SE Radford, AE Ashcroft	The Journal of biological chemistry	2004
In Vitro and in Vivo Interactions of Homocysteine with Human Plasma Transthyretin A Lim, S Sengupta, ME McComb, R Théberge, WG Wilson, CE Costello, DW Jacobsen	The Journal of biological chemistry	2003
Dialysis-Related Amyloidosis Revisited MF Lam, S Tang, KN Lai	The International Journal of Artificial Organs	2003
ß 2 -Microglobulin Clearance with Super High Flux Hemodialysis: an Ex Vivo Study WC Lee, S Uchino, N Fealy, I Baldwin, S Panagiotopoulos, H Goehl, S Morgera, HH Neumayer, R Bellomo	The International Journal of Artificial Organs	2003
Sequence and Expression Analysis Of The β-2-Microglobulin Gene In Dialysis Patients S Canaider, GL Manna, P Strippoli, D Rondelli, G Cianciolo, G Donati, R Casadei, M Arpinati, S Stefoni, P Carinci	Amyloid	2002
Rare presentation of intestinal amyloidosis with acute intestinal pseudo-obstruction and perforation SB Ng, IA Busmanis	Journal of clinical pathology	2002
UNINEPHRECTOMY INCREASES KIDNEY β2-MICROGLOBULIN: CAN IT PLAY A ROLE IN THE PROGRESSION OF KIDNEY DAMAGE? C Bianchi, C Donadio, G Tramonti, C Consani, P Lorusso, C Bonino, F Lunghi	Renal Failure	2001
Evaluation of99mTc-MAMA-chrysamine G as anin vivoprobe for amyloidosis NA Dezutter, WJ Landman, PL Jager, TJ de Groot, PJ Dupont, PC Tooten, B Zekarias, E Gruys, AM Verbruggen	Amyloid	2001
Modalities for the Removal of β2-Microglobulin from Blood GA Ameer	Seminars in Dialysis	2001
Symptomatic destructive spondyloarthropathy secondary to β2-microglobulin amyloidosis. Report of four cases JM Campisto, S Garcia, A Combalia, M Sole, R Ramon	Amyloid	2001
Dynamic of β2-Microglobulin Fibril Formation and Reabsorption: The Role of Proteolysis V Bellotti, M Gallieni, S Giorgetti, D Brancaccio	Seminars in Dialysis	2001
Structural diversity of ex vivo amyloid fibrils studied by cryo-electron microscopy JL Jiménez, G Tennent, M Pepys, HR Saibil	Journal of Molecular Biology	2001
Congophilicity (Congo red affinity) of different β2-microglobulin conformations characterized by dye affinity capillary electrophoresis NH Heegaard, JW Sen, MH Nissen	Journal of Chromatography A	2000
Amyloidosis and the respiratory tract JD Gillmore, PN Hawkins	Thorax	1999
Quality Assurance in Dialysis LW Henderson, RS Thuma		1998
β2-microglobulin amyloidosis J Kay	Amyloid	1997
Amyloid β2-microglobulin is modified with imidazolone, a novel advanced glycation end product, in dialysis-related amyloidosis T Niwa, T Katsuzaki, S Miyazaki, T Momoi, T Akiba, T Miyazaki, K Nokura, F Hayase, N Tatemichi, Y Takei	Kidney International	1997
Ultrastructural organization of hemodialysis-associated β2-microglobulin amyloid fibrils S Inoue, M Kuroiwa, K Ohashi, M Hara, R Kisilevsky	Kidney International	1997
Suki and Massry’s THERAPY OF RENAL DISEASES AND RELATED DISORDERS WN Suki, SG Massry		1997
A case of carpal tunnel syndrome due to dialysis-related amyloidosis in a patient undergoing long-term hemodialysis. Chung YJ, Choi KC, Ha JH, Kim KY, Lee SC, Kim SW, Kim NH, Kang YJ, Moon ES, Lee MC	The Korean Journal of Internal Medicine	1997
Amyloid β2-microglobulin is modified with Nɛ-(carboxymethyl)lysine in dialysis-related amyloidosis T Niwa, M Sato, T Katsuzaki, T Tomoo, T Miyazaki, N Tatemichi, Y Takei, T Kondo	Kidney International	1996
Polymerization of normal and intact β2-microglobulin as the amyloidogenic protein in dialysis-amyloidosis JM Campistol, D Bernard, G Papastoitsis, M Solé, J Kasirsky, M Skinner	Kidney International	1996
Dialysis-related amyloidosis: Pathogenetic aspects and therapeutic considerations J Schaeffer, G Ehlerding, KM Koch	Nephrology	1996
Regenerated Cellulose-Based Hemodialyzers with Immobilized Proteins as Potential Devices for Extracorporeal Immunoadsorption Procedures: An Assessment of Protein Coupling Capacity and In Vitro Dialysis Performances L Vallar, C Rivat	Artificial Organs	1996
Modification of β2m with advanced glycation end products as observed in dialysis-related amyloidosis by 3-DG accumulating in uremic serum T Niwa, T Katsuzaki, T Momoi, T Miyazaki, H Ogawa, A Saito, S Miyazaki, K Maeda, N Tatemichi, Y Takei	Kidney International	1996
Clinical Manifestations and Pathogenesis of Dialysis-Related Amyloidosis SM Sprague, SM Moe	Seminars in Dialysis	1996
Upper extremity musculoskeletal manifestations of dialysis-associated amyloidosis DC Fitzpatrick, PJ Jebson, SM Madey, CM Steyers	The Iowa orthopaedic journal	1996
Beta-amyloid peptide blocks the fast-inactivating K+ current in rat hippocampal neurons TA Good, DO Smith, RM Murphy	Biophysical Journal	1996
The role of proteolytic enzymes in the deposition of amyloid proteins A Sato, M Kawamura, M Nishioka, S Nakamura, J Minaguchi	Advances in Enzyme Regulation	1996
High prevalence of pancreatic islet amyloid in patients with end-stage renal failure on dialysis treatment EJ de Koning, KA Fleming, DW Gray, A Clark	The Journal of Pathology	1995
Role of IL-1β and prostaglandins in β2-microglobulin-induced bone mineral dissolution SM Moe, BK Hack, SA Cummings, SM Sprague	Kidney International	1995
Shoulder Pain in the Dialysis Patient J Kay	Seminars in Dialysis	1995
Immunohistochemical detection of advanced glycation end products in dialysis-related amyloidosis T Niwa, S Miyazaki, T Katsuzaki, N Tatemichi, Y Takei, T Miyazaki, T Morita, Y Hirasawa	Kidney International	1995
Immunoadsorption procedure as a potential method for the specific β2-microglobulin removal from plasma of patients with chronic renal failure L Vallar, PM Costa, A Teixeira, M Pfister, R Barrois, PP Costa, C Rivat	Journal of Chromatography B Biomedical Sciences and Applications	1995
Advanced glycosylation end products in diabetic renal and vascular disease R Bucala, H Vlassara	American Journal of Kidney Diseases	1995
Dialysis-Associated Amyloidosis T Drüeke, M Touam, J Zingraff	Advances in renal replacement therapy	1995
Unifying features of systemic and cerebral amyloidosis J Ghiso, T Wisniewski, B Frangione	Molecular Neurobiology	1994
Role of 1–123 serum amyloid Srotein in the etection of familial amyloidosis in Oriental cats K Piirsalu, R McLean, R Zuber, K Bannistert, S Penglis, J Bellen, R Bais	Journal of Small Animal Practice	1994
Diffusive and convective solute transport through hemodialysis membranes: A hydrodynamic analysis LJ Langsdorf, AL Zydney	Journal of Biomedical Materials Research	1994
Determinants of the serum concentrations of low molecular weight proteins in patients on maintenance hemodialysis A Kabanda, M Jadoul, JM Pochet, R Lauwerys, CY de Strihou, A Bernard	Kidney International	1994
Dialysis-associated arthropathy — Role of age M Kessler, P Netter, M Claudon, A Gaucher	Geriatric Nephrology and Urology	1994
β2-Microglobulin Amyloidosis: Illustrative Cases MM Picken, S Shen	Ultrastructural Pathology	1994
β2-Microglobulin and the Kidney: An Overview EA Turbat-Herrera	Ultrastructural Pathology	1994
Molecular variants of beta 2-microglobulin in renal insufficiency C Vincent, L Dennoroy, JP Revillard	Biochemical Journal	1994
Excess-substrate inhibition in enzymology and high-dose inhibition in pharmacology: a reinterpretation [corrected] PW Kühl	Biochemical Journal	1994
Diagnosis and monitoring of amyloidosis PN Hawkins	Baillière's Clinical Rheumatology	1994
Role of Bioincompatibility in Dialysis Morbidity and Mortality JM Lazarus, WF Owen	American Journal of Kidney Diseases	1994
In Vivo Effect of β2-Microglobulin on Bone Resorption J Petersen, MS Kang	American Journal of Kidney Diseases	1994
Behavior of Beta 2-microglobulin (B2-m) serum levels in uremic patients VA Mioli, E Balestra, L Bibiano, S Dellabella, E Fanciulli, G Gaffi, A Perilli, F Petroselli, AM Ricciatti, P Carletti	The International Journal of Artificial Organs	1994
Amyloid Bone Disease and Highly Permeable Synthetic Membranes M Boccalatte, G Pratesi, G Calabrese, A Bignazzi, M Gonella	The International Journal of Artificial Organs	1994
Complement Activation in Dialysis: Effects on Cytokines, Lymphocyte Activation and β 2 Microglobulin M Gardinali, A Calcagno, L Conciato, A Agostoni, A Rosti, P Cori, N Vozzo, A Moroni, A Anelli, U Zoni, MD Prete	The International Journal of Artificial Organs	1994
The Textbook of Peritoneal Dialysis R Gokal, KD Nolph		1994
Bioincompatibility Plays a Major Role in β2-Microglobulin Amyloidosis CR DiRaimondo, VE Pollak	Seminars in Dialysis	1993
De Novo Amyloidosis in a Renal Allograft: A Case Report and Review of the Literature KL Harrison, CE Alpers, CL Davis	American Journal of Kidney Diseases	1993
Bone Disease in Kidney Failure: Diagnosis and Management RE Cronin	The American Journal of the Medical Sciences	1993
Serum Alpha-1-Antitrypsin in Hemodialysis Patients with Dialysis Arthropathy D Docci, R Bilancioni, L Baldrati, C Capponcini, C Delvecchio, C Feletti	The International Journal of Artificial Organs	1993
Reduction of Disulfide Bonds in an Amyloidogenic Bence Jones Protein Leads to Formation of “Amyloid-Like” Fibrils in Vitro HW KLAFKI, AI PICK, I PARDOWITZ, T COLE, LA AWNI, HU BARNIKOL, F MAYER, HD KRATZIN, N HILSCHMANN	Biological Chemistry Hoppe-Seyler	1993
Biological Barriers to Protein Delivery KL Audus, TJ Raub		1993
Iodine-123-labelled serum amyloid P component scintigraphy in amyloidosis R Sale, M Deveaux, E Hachulla, J Descamps, B Duquesnoy, X Marchandise	European Journal of Nuclear Medicine	1993
Complement neoantigen and vitronectin are components of plaques in amyloid AL neuropathy GL Zanusso, G Moretto, B Bonetti, S Monaco, N Rizzuto	The Italian Journal of Neurological Sciences	1992
Demonstration of plasma proteinase inhibitors in β2-microglobulin amyloid deposits JM Campistol, T Shirahama, CR Abraham, OG Rodgers, M Solé, AS Cohen, M Skinner	Kidney International	1992
Backfiltration During Dialysis: A Critical Assessment J Petersen, SW Hyver, J Cajias	Seminars in Dialysis	1992
In vitro spontaneous synthesis of beta 2-microglobulin amyloid fibrils in peripheral blood mononuclear cell culture JM Campistol, M Solé, JA Bombi, R Rodriguez, E Mirapeix, J Muñoz-Gomez, OW Revert	The American Journal of Pathology	1992
Dialysis-related amyloidosis KM Koch	Kidney International	1992
Proton NMR assignments and secondary structure of human .beta.2-microglobulin in solution M Okon, P Bray, D Vucelic	Biochemistry	1992
Granulocyte Elastase, β-Thromboglobulin, and C3D during Acetate or Bicarbonate Hemodialysis with Hemophan® Compared to a Cellulose Acetate Membrane BG Stegmayr, K Esbensen, A Gutierrez, L Lundberg, B Nielsen, CE Stroemsaeter, B Wehle	The International Journal of Artificial Organs	1992
Beta 2-Microglobulin Synthesis of Mononuclear Cells in Chronic Dialysis Patients K Kumano, M Nanbu, S Kusakari, T Sakai	The International Journal of Artificial Organs	1992
In Vivo Clearance and Elimination of Nine Marker Substances during Hemofiltration with Different Membranes BK Krämer, A Pickert, C Hohmann, HM Liebich, GA Müller, M Hablitzel, T Risler	The International Journal of Artificial Organs	1992
Aktuelle Aspekte der Osteologie TH Ittel, HG Sieberth, HH Matthiaß		1992
Aberrant cytokine production from tenosynovium in dialysis associated amyloidosis N Miyasaka, K Sato, Y Kitano, M Higaki, K Nishioka, K Ohta	Annals of the rheumatic diseases	1992
Serum ?1-microglobulin and ?2-microglobulin for the estimation of fetal glomerular renal function S Nolte, B Mueller, W Pringsheim	Pediatric Nephrology	1991
Beta2-microglobulin deposition in bone in chronic renal failure S Qnishi, DL Andress, NA Maloney, JW Coburn, DJ Sherrard	Kidney International	1991
Stimulation of beta2-microglobulin synthesis in lymphocytes after exposure to Cuprophan dialyzer membranes B Jahn, M Betz, R Deppisch, O Janssen, GM Hänsch, E Ritz	Kidney International	1991
Effect of dialysis membrane and patient's age on signs of dialysis-related amyloidosis CY de Strihou, M Jadoul, J Malghem, B Maldague, J Jamart	Kidney International	1991
Beta2-microglobulin kinetics in end-stage renal failure RA Odell, P Slowiaczek, JE Moran, K Schindhelm	Kidney International	1991
Structural modifications of human beta 2 microglobulin treated with oxygen-derived radicals C Capeillere-Blandin, T Delaveau, B Descamps-Latscha	Biochemical Journal	1991
Imaging of haemodialysis-associated amyloidosis with 123I-serum amyloid P component SR Nelson, PN Hawkins, S Richardson, MB Pepys, JP Lavender, D Sethi, PE Gower, CW Pugh, CG Winearls, DO Oliver	The Lancet	1991
Purification and partial characterization of a new 85 KDa amyloidosis-related protein in chronic hemodialysis D Brancaccio, GM Ghiggeri, A Garberi, A Anelli, F Ginevri, G Loggi, R Gusmano	Biochemical and Biophysical Research Communications	1991
Can the Nephrologist Prevent Dialysis-Related Amyloidosis? J Zingraff, T Drüeke	American Journal of Kidney Diseases	1991
Increased Concentrations of Free Light Chain Lambda in Sera from Chronic Hemodialysis Patients K Wakasugi, M Sasaki, M Suzuki, N Azuma, T Nobuto	Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology	1991
An Experimental Study on Selective Elimination of β2-Microglobulin Using Immunoadsorption Method in Patients with Chronic Renal Failure H Nakano, H Gomi, T Shibasaki, F Ishimoto, O Sakai	Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology	1991
Amyloid and Amyloidosis 1990 JB Natvig, Ø Førre, G Husby, A Husebekk, B Skogen, K Sletten, P Westermark		1991
Pathological fractures and lytic bone lesion of the femoral neck associated with ?2-microglobulin amyloid deposition in long-term dialysis patients GF Scheumann, M Holch, ML Nerlich, A Brandis, H Ostertag, H Tscherne	Archives of Orthopaedic and Trauma Surgery	1991
High affinity interactions between the Alzheimer's beta-amyloid precursor proteins and the basement membrane form of heparan sulfate proteoglycan S Narindrasorasak, D Lowery, P Gonzalez-DeWhitt, RA Poorman, B Greenberg, R Kisilevsky	The Journal of biological chemistry	1991
Imaging of dialysis-related amyloid (AB-amyloid) deposits with 131I-β2-microglobulin J Floege, W Burchert, A Brandis, P Gielow, B Nonnast-Daniel, E Spindler, H Hundeshagen, S Shaldon, KM Koch	Kidney International	1990
Serumspiegel und organablagerungen vonΒ 2-mikroglobulin bei dialysepatienten G Stein, A Schneider, H To\, R Linke, K Schaefer, E Ritz	Klinische Wochenschrift	1990
β 2-microglobulin amyloidosis CP Maury	Rheumatology International	1990
Assessing the adequacy of dialysis RM Hakim	Kidney International	1990
New Insights into the Pathogenesis of Hemodialysis-Associated Amyloidosis A Argilés, G Mourad, RC Atkins, CM Mion	Seminars in Dialysis	1990
Amyloses — Aspects biochimiques G Grateau	La Revue de Médecine Interne	1990
A Study of β2-Microglobulin Skin Deposits in Dialyzed Patients and Healthy Controls AG Assounga, S Bascoul, B Canaud, PA Bouya, JP Vendrell, JP Sciolla, G Mourad, P Baldet, A Serre, C Mion	American Journal of Kidney Diseases	1990
Tumor Necrosis Factor, Interleukin-1 and Beta 2-Microglobulin Levels in Chronic Hemodialysis Patients RJ Caruana, SA Lobel, MS Leffell, H Campbell, PL Cheek	The International Journal of Artificial Organs	1990
International Yearbook of Nephrology 1990 VE Andreucci, LG Fine, CM Kjellstrand, N Sugino		1990
Serumspiegel und organablagerungen vonΒ 2-mikroglobulin bei dialysepatienten G Stein, A Schneider, H To, R Linke, K Schaefer, E Ritz	Klinische Wochenschrift	1990
β 2-microglobulin amyloidosis: A systemic amyloid disease affecting primarily synovium and bone in long-term dialysis patients CP Maury	Rheumatology International	1990
The Interleukin Hypothesis: A Reappraisal after 6 Years S Shaldon	Seminars in Dialysis	1989
Amyloid syndromes associated with hemodialysis KS Kleinman, JW Coburn	Kidney International	1989
Erosive Spondyloarthropathy in a Long-Term Chronic Hemodialysis Patient WF Owen	Seminars in Dialysis	1989
Rheumatic syndromes and β2-microglobulin amyloidosis in patients receiving long-term peritoneal dialysis F Cornéalis, T Bardin, B Faller, C Verger, M Allouache, P Raymond, J Rottembourg, D Tourlière, C Benhamou, LH Noel, D Kuntz	Arthritis & Rheumatism	1989
Lysine-specific cleavage of β2-microglobulin in amyloid deposits associated with hemodialysis RP Linke, H Hampl, H Lobeck, E Ritz, J Bommer, R Waldherr, M Eulitz	Kidney International	1989
Comparison of Various Treatment Modes in Terms of ß2-Microglobulin Removal: Hemodialysis, Hemofiltration, and Push/Pull HDF T Shinzato, H Kobayakawa, K Maeda	Artificial Organs	1989
Adsorption of β2-Microglobulin on PMMA, PAN and cellulosic membranes K Sakai, M Nagase, S Tsuda	The Chemical Engineering Journal	1989
β2-Microglobulin Kinetics in Maintenance Hemodialysis: A Comparison of Conventional and High-Flux Dialyzers and the Effects of Dialyzer Reuse CR DiRaimondo, VE Pollak	American Journal of Kidney Diseases	1989
A Study of the Basic Principles Determining the Performance of Several High-Flux Dialyzers KK Jindal, J McDougall, B Woods, L Nowakowski, MB Goldstein	American Journal of Kidney Diseases	1989
Infarction of intestine with massive amyloid deposition in two patients on long-term hemodialysis HH Choi, D Heller, MM Picken, GS Sidhu, T Kahn	Gastroenterology	1989
Adsorption of ß2-Microglobulin on Dialysis Membranes: Comparison of Different Dialyzers and Effects of Reuse Procedures M Goldman, M Lagmiche, M Dhaene, Z Amraoui, C Thayse, JL Vanherweghem	The International Journal of Artificial Organs	1989
Clinical Evaluation of a New High-Flux Cellulose Acetate Membrane RM Schaefer, L Huber, U Gilge, K Bausewein, J Vienken, A Heidland	The International Journal of Artificial Organs	1989
'Dialysis related arthropathy': a survey of 95 patients receiving chronic haemodialysis with special reference to beta 2 microglobulin related amyloidosis NP Hurst, R van den Berg, A Disney, M Alcock, L Albertyn, M Green, V Pascoe	Annals of the rheumatic diseases	1989
Beta-2 Microglobulin Amyloidosis in a Patient on LongTerm Continuous Ambulatory Peritoneal Dialysis (CAPD) A Colombi, W Wegmann	Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis	1989
Beta-2 Microglobulin in Patients on Peritoneal Dialysis and Hemodialysis A Scalamogna, E Imbasciati', AD Vecchi, C Castelnovo, B Pagliari', VD Cristofaro', C Ponticelli	Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis	1989
Amyloidosis PN Hawkins	Blood Reviews	1988
Dialysis — relatedβ2 microglobulin — Amyloid arthropathy Improvement of clinical symptoms after a switch of dialysis membranes P Hardouin, RM Flipo, P Foissac-Gegoux, A Dumont, B Duquesnoy, B Delcambre	Clinical Rheumatology	1988
Methods for Staining Amyloid in Tissues: A Review MT Elghetany, A Saleem	Biotechnic & Histochemistry	1988
DIAGNOSTIC RADIONUCLIDE IMAGING OF AMYLOID: BIOLOGICAL TARGETING BY CIRCULATING HUMAN SERUM AMYLOID P COMPONENT PN Hawkins, JP Lavender, MJ Myers, MB Pepys	The Lancet	1988
Beta-2-Microglobulin Adsorption and Release in-Vitro: Influence of Membrane Material, Osmolality and Heparin B Klinke, A Röckel, W Perschel, S Abdelhamid, P Fiegel, D Walb, S Meairs	The International Journal of Artificial Organs	1988
The Kidney in Plasma Cell Dyscrasias L Minetti, G DAmico, C Ponticelli		1988
Beta-2 Microglobulin in Peritoneal Dialysis Patients: Serum Levels and Peritoneal Clearances CR DiRaimondo, P McCarley, WJ Stone	Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis	1988
Dialysis — relatedβ2 microglobulin — Amyloid arthropathy Improvement of clinical symptoms after a switch of dialysis membranes P Hardouin, , P Foissac-Gegoux, A Dumont, B Duquesnoy, B Delcambre	Clinical Rheumatology	1988
Reply to letter by Casey et a1 JP Huaux, H Noël, JM Vandenbroucke, CY de van Strihou, CD Deuxchaisnes	Arthritis & Rheumatism	1987
β2-microglobulin: Its significance in the evaluation of renal function GH Schardijn, LW van Eps	Kidney International	1987
β2-Microglobulin, Different Fragments and Polymers thereof in Synovial Amyloid in Long-Term Hemodialysis RP LINKE, H HAMPL, S BARTEL-SCHWARZE, M EULITZ	Biological Chemistry Hoppe-Seyler	1987
Chemical heterogeneity of amyloid in the carpal tunnel syndrome K Stein, S St�rkel, RP Linke, HH Goebel	Virchows Archiv A Pathological Anatomy and Histopathology	1987
Degradation and deposition of amyloid AA fibril are tissue specific F Prelli, M Pras, B Frangione	Biochemistry	1987
Aβ 2 m Amyloidosis CR Raimondo, WJ Stone	The International Journal of Artificial Organs	1987
Synovial amyloid in chronic haemodialysis contains beta 2 microglobulin FE Bruckner, M Burke, RS Pereira, AJ Eisinger, M Bending, J Kwan, AK Osman, B Watson	Annals of the rheumatic diseases	1987
Dialysis arthropathy, amyloidosis and beta-2 microglobulin JS Cameron	Pediatric Nephrology	1987
Systemic amyloidosis of beta 2-microglobulin type: a complication of long-term haemodialysis JM Theaker, AE Raine, AJ Rainey, A Heryet, A Clark, DO Oliver	Journal of clinical pathology	1987
Uremia Therapy HJ Gurland		1987
Pathologie des Bandapparates W Mohr		1987
Chemical heterogeneity of amyloid in the carpal tunnel syndrome K Stein, S Strkel, RP Linke, HH Goebel	Virchows Archiv A Pathological Anatomy and Histopathology	1987
Dialysis-related amyloid is amyloid of beta-2-microglobulin (AMβ2M) origin TT Casey, WJ Stone, CR Diraimondo, DL Page, PD Gorevic	Arthritis & Rheumatism	1986
HAEMODIALYSIS MEMBRANES, SERUM β2-MICROGLOBULIN, AND DIALYSIS AMYLOIDOSIS D Hauglustaine, M Waer, P Michielsen, J Goebels, M Vandeputte	The Lancet	1986
β2-MICROGLOBULIN-ASSOCIATED AMYLOIDOSIS IN CHRONIC HAEMODIALYSIS PATIENTS J Chanard, S Lavaud, O Toupance, JP Melin, P Gillery, JP Revillard	The Lancet	1986
Polymerization of intact beta 2-microglobulin in tissue causes amyloidosis in patients on chronic hemodialysis PD Gorevic, PC Munoz, TT Casey, CR DiRaimondo, WJ Stone, FC Prelli, MM Rodrigues, MD Poulik, B Frangione	Proceedings of the National Academy of Sciences	1986
Primary amyloidosis associated with multiple myeloma. Predictors of successful therapy K Fielder, BG Durie	The American Journal of Medicine	1986
Tumoral amyloidosis of bone of beta2-microglobulin origin in association with long-term hemodialysis: A new type of amyloid disease TT Casey, WJ Stone, CR Diraimondo, BD Brantley, CV Diraimondo, PD Gorevic, DL Page	Human Pathology	1986
Amyloid kidney stone of uremic patients consist of Beta2-microglobulin fragments RP Linke, J Bommer, E Ritz, R Waldherr, M Eulitz	Biochemical and Biophysical Research Communications	1986
Inhibitory effects of β2-microglobulin on in vitro calcification of osteoblastic cells H Kataoka, F Gejyo, S Yamada, T Kunitomo, M Arakawa	Biochemical and Biophysical Research Communications	1986
Therapy of Renal Diseases and Related Disorders WN Suki, SG Massry		1984
Contemporary Nephrology S Klahr, SG Massry		1981
Replacement of Renal Function by Dialysis W Drukker, FM Parsons, JF Maher		1979

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