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T Ganz, … , D F Bainton, R I Lehrer
Published October 1, 1985
Citation Information: J Clin Invest. 1985;76(4):1427-1435. https://doi.org/10.1172/JCI112120.
Citation Information: J Clin Invest. 1985;76(4):1427-1435. https://doi.org/10.1172/JCI112120.
Abstract
We extracted a granule-rich sediment from normal human neutrophils and subjected it to chromatographic, electrophoretic, and functional analysis. The extract contained three small (molecular weight less than 3,500) antibiotic peptides that were named human neutrophil peptide (HNP)-1, HNP-2, and HNP-3, and which will be referred to as "defensins." HNP 1-3, a mixture of the three defensins, killed Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli effectively in vitro when tested in 10 mM phosphate buffer containing certain nutrients, but it had little or no bactericidal activity in nutrient-free buffer. In contrast, the nutrient-free buffer supported a high degree of activity by HNP 1-3 against Cryptococcus neoformans. In addition to its antibacterial and antifungal properties, HNP 1-3 directly inactivated herpes simplex virus, Type 1. Two of the individual purified defensins, HNP-1 and HNP-2, were as microbicidal as the mixture HNP 1-3. HNP-3 was less active than the other defensins against most but not all of the microbes tested. Immunoperoxidase stains revealed HNP 1-3 to have a granular localization in the neutrophil's cytoplasm by light microscopy. Frozen thin section immunogold transmission electron microscopy showed HNP 1-3 to be localized in azurophil granules. These studies define a broad-spectrum antimicrobial system in human neutrophils. The defensin system may operate in conjunction with or independently from oxygen-dependent microbicidal processes to enable human neutrophils to inactivate and destroy potential pathogens.
Authors
T Ganz, M E Selsted, D Szklarek, S S Harwig, K Daher, D F Bainton, R I Lehrer
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Antibiotics: A Bibliometric Analysis of Top 100 Classics
AI Arshad, P Ahmad, MI Karobari, JA Asif, MK Alam, Z Mahmood, NA Rahman, N Mamat, MA Kamal |
Antibiotics | 2020 |
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A Crosstalk on Antimicrobial Peptides
A Borah, B Deb, S Chakraborty |
International Journal of Peptide Research and Therapeutics | 2020 |
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Identification and characterization of urinary peptides using Q-TOF mass spectrometry in cow
A Sharma, R Nigam, A Kumar, A Pal |
2020 | |
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Human Antimicrobial Peptides: Spectrum, Mode of Action and Resistance Mechanisms
BS Bazzaz, S Seyedi, NH Goki, B Khameneh |
International Journal of Peptide Research and Therapeutics | 2020 |
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Antimicrobial Peptides: An Approach to Combat Resilient Infections
D Parai, P Dey, SK Mukherjee |
Current drug discovery technologies | 2020 |
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Antibiotics: A Bibliometric Analysis of Top 100 Classics.
Arshad AI, Ahmad P, Karobari MI, Asif JA, Alam MK, Mahmood Z, Abd Rahman N, Mamat N, Kamal MA |
2020 | |
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Histone-induced thrombotic thrombocytopenic purpura in adamts13 −/− zebrafish depends on von Willebrand factor
L Zheng, MS Abdelgawwad, D Zhang, L Xu, S Wei, W Cao, XL Zheng |
Haematologica | 2019 |
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Reassessing the Host Defense Peptide Landscape
EF Haney, SK Straus, RE Hancock |
Frontiers in Chemistry | 2019 |
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Expression and Function of Host Defense Peptides at Inflammation Sites
SV Prasad, K Fiedoruk, T Daniluk, E Piktel, R Bucki |
International journal of molecular sciences | 2019 |
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Antimicrobial Peptides: Basics for Clinical Application
K Matsuzaki |
2019 | |
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Antimicrobial Peptides: Basics for Clinical Application
K Matsuzaki |
2019 | |
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Antimicrobial Peptides: Basics for Clinical Application
K Matsuzaki |
2019 | |
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Human neutrophil peptide-1 inhibits thrombus formation under arterial flow via its terminal free cysteine thiols
JK McDaniel, MS Abdelgawwad, A Hargett, MB Renfrow, K Bdeir, W Cao, DB Cines, XL Zheng |
Journal of Thrombosis and Haemostasis | 2019 |
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The role of alpha defensin in prosthetic joint infection (PJI) diagnosis: a literature review
T Bonanzinga, MC Ferrari, G Tanzi, F Vandenbulcke, A Zahar, M Marcacci |
EFORT Open Reviews | 2019 |
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A comparative study of intraoperative frozen section and alpha defensin lateral flow test in the diagnosis of periprosthetic joint infection
IK Sigmund, J Holinka, S Lang, S Stenicka, K Staats, G Hobusch, B Kubista, R Windhager |
Acta Orthopaedica | 2019 |
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Neutrophilic proteolysis in the cystic fibrosis lung correlates with a pathogenic microbiome
RA Quinn, S Adem, RH Mills, W Comstock, LD Goldasich, G Humphrey, AA Aksenov, AV Melnik, R da Silva, G Ackermann, N Bandeira, DJ Gonzalez, D Conrad, AJ ODonoghue, R Knight, PC Dorrestein |
Microbiome | 2019 |
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TmToll-7 Plays a Crucial Role in Innate Immune Responses Against Gram-Negative Bacteria by Regulating 5 AMP Genes in Tenebrio molitor
S Park, YH Jo, KB Park, HJ Ko, CE Kim, YM Bae, B Kim, SA Jun, IS Bang, YS Lee, YJ Kim, YS Han |
Frontiers in immunology | 2019 |
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DEFB1 rs11362 Polymorphism and Risk of Chronic Periodontitis: A Meta-Analysis of Unadjusted and Adjusted Data
J Shao, M Zhang, L Wu, XW Jia, YH Jin, XT Zeng |
Frontiers in Genetics | 2019 |
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Plant defensins: types, mechanism of action and prospects of genetic engineering for enhanced disease resistance in plants
RS Khan, A Iqbal, R Malak, K Shehryar, S Attia, T Ahmed, MA Khan, M Arif, M Mii |
3 Biotech | 2019 |
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Human β-defensin-3 participates in intra-amniotic host defense in women with labor at term, spontaneous preterm labor and intact membranes, and preterm prelabor rupture of membranes
R Para, R Romero, D Miller, B Panaitescu, A Varrey, T Chaiworapongsa, SS Hassan, CD Hsu, N Gomez-Lopez |
Journal of Maternal-Fetal and Neonatal Medicine | 2019 |
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Synovial fluid α-defensin in the diagnosis of periprosthetic joint infection: the lateral flow test is an effective intraoperative detection method
X Han, K Xie, X Jiang, L Wang, H Wu, X Qu, M Yan |
Journal of orthopaedic surgery and research | 2019 |
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Human salivary proteins and their peptidomimetics: Values of function, early diagnosis, and therapeutic potential in combating dental caries
K Wang, X Zhou, W Li, L Zhang |
Archives of Oral Biology | 2019 |
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Systematic mutational analysis of human neutrophil α-defensin HNP4
H Hu, B Di, WD Tolbert, N Gohain, W Yuan, P Gao, B Ma, Q He, M Pazgier, L Zhao, W Lu |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 2019 |
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Development of a multiplex and sensitive lateral flow immunoassay for the diagnosis of periprosthetic joint infection
TT Tsai, TH Huang, NY Ho, YP Chen, CA Chen, CF Chen |
Scientific Reports | 2019 |
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Human α defensins promote the expression of the inflammatory cytokine interleukin‐8 under high‐glucose conditions: Novel insights into the poor healing of diabetic foot ulcers
L Meng, X Guo, X Yang, H Liu, M Yu, Y Wu, Z Zhu |
Journal of Biochemical and Molecular Toxicology | 2019 |
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Diagnostic Accuracy of the Alpha-Defensin Test for Periprosthetic Joint Infection in Patients With Inflammatory Diseases
Y Miyamae, J George, AK Klika, WK Barsoum, CA Higuera |
The Journal of Arthroplasty | 2019 |
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Contemporary Management of Temporomandibular Disorders: Surgical Treatment
ST Connelly, GM Tartaglia, RG Silva |
2019 | |
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Bacterial Adaptation to Co-resistance
SM Mandal, D Paul |
2019 | |
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Critical determinants of human neutrophil peptide 1 for enhancing host epithelial adhesion of Shigella flexneri
C Liao, K Fang, J Xiao, W Zhang, B Zhang, W Yuan, W Lu, D Xu |
Cellular Microbiology | 2019 |
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The antimicrobial peptide database provides a platform for decoding the design principles of naturally occurring antimicrobial peptides
G Wang |
Protein science : a publication of the Protein Society | 2019 |
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Maturation of an Antimicrobial Peptide Inhibits Aeromonas hydrophila Infection in Crayfish
BR Zhao, Y Zheng, J Gao, XW Wang |
Journal of immunology (Baltimore, Md. : 1950) | 2019 |
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The Impact of α-Defensin Test in Diagnosing Periprosthetic Infection After Total Ankle Arthroplasty
DM Thiesen, A Koniker, T Gehrke, P Linke, M Ohlmeier, J Salber, M Citak |
The Journal of Foot & Ankle Surgery | 2019 |
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Reliability of synovial fluid alpha-defensin and leukocyte esterase in diagnosing periprosthetic joint infection (PJI): a systematic review and meta-analysis
Y Chen, X Kang, J Tao, Y Zhang, C Ying, W Lin |
Journal of orthopaedic surgery and research | 2019 |
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Defensinas humanas y su función en cavidad oral
MI Ortiz-Casillas, CR Alvizo-Rodríguez, YM Ortíz-García, MG Fuentes-Lerma, M Gutiérrez-Angulo, RP Mariaud-Schmidt |
2019 | |
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Modulation of Human Neutrophil Peptides on P. aeruginosa Killing, Epithelial Cell Inflammation and Mesenchymal Stromal Cell Secretome Profiles Q Dai, Y Morita, Y Huang, PC Liaw, J Wu, J Khang, D Islam, K Yu, Y Li, H Zhang |
Journal of inflammation research | 2019 |
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Antibacterial Peptides in Dermatology–Strategies for Evaluation of Allergic Potential
M Deptuła, A Wardowska, M Dzierżyńska, S Rodziewicz-Motowidło, M Pikuła |
Molecules (Basel, Switzerland) | 2018 |
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Towards the Application of Human Defensins as Antivirals
MS Park, JI Kim, I Lee, S Park, JY Bae, MS Park |
Biomolecules & therapeutics | 2018 |
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Multifaceted immune functions of human defensins and underlying mechanisms
S Fruitwala, DW El-Naccache, TL Chang |
Seminars in Cell & Developmental Biology | 2018 |
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Macrocyclic θ-defensins suppress tumor necrosis factor-α (TNF-α) shedding by inhibition of TNF-α–converting enzyme
JB Schaal, T Maretzky, DQ Tran, PA Tran, P Tongaonkar, CP Blobel, AJ Ouellette, ME Selsted |
The Journal of biological chemistry | 2018 |
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The Ontogeny of a Neutrophil: Mechanisms of Granulopoiesis and Homeostasis
SM Lawrence, R Corriden, V Nizet |
Microbiology and molecular biology reviews : MMBR | 2018 |
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Neutrophil α-defensins promote thrombosis in vivo by altering fibrin formation, structure, and stability
R Abu-Fanne, V Stepanova, RI Litvinov, S Abdeen, K Bdeir, M Higazi, E Maraga, C Nagaswami, AR Mukhitov, JW Weisel, DB Cines, AA Higazi |
Blood | 2018 |
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Alpha-defensins (α-Defs) in Crohn's disease: decrease of ileal α-Def 5 via permanent methylation and increase in plasma α-Def 1-3 concentrations offering biomarker utility: Alpha-defensins in ileal Crohn's disease
E Cerrillo, I Moret, M Iborra, D Ramos, E Busó, L Tortosa, E Sáez-González, P Nos, B Beltrán |
Clinical & Experimental Immunology | 2018 |
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The Accuracy of the Alpha Defensin Lateral Flow Device for Diagnosis of Periprosthetic Joint Infection: Comparison with a Gold Standard
T Gehrke, C Lausmann, M Citak, T Bonanzinga, L Frommelt, A Zahar |
The Journal of Bone and Joint Surgery. American volume. | 2018 |
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Relative Deficiency of Plasma A Disintegrin and Metalloprotease with Thrombospondin Type 1 Repeats 13 Activity and Elevation of Human Neutrophil Peptides in Patients with Traumatic Brain Injury
MA Kumar, W Cao, HP Pham, D Raju, K Nawalinski, E Maloney-Wilensky, J Schuster, XL Zheng |
Journal of Neurotrauma | 2018 |
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What Is the Optimal Criteria to Use for Detecting Periprosthetic Joint Infections Before Total Joint Arthroplasty?
S Kanwar, AA Al-Mansoori, MR Chand, JM Villa, JC Suarez, PD Patel |
The Journal of Arthroplasty | 2018 |
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Detection of α–defensin in blister fluids as potential biomarkers for bullous pemphigoid patients by matrix-assisted laser desorption ionization/time-of-flight mass spectrometry
CY Wu, LH Lo, H Su, J Shiea |
Clinica chimica acta; international journal of clinical chemistry | 2018 |
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Low sensitivity of a-defensin (Synovasure) test for intraoperative exclusion of prosthetic joint infection
R Scholten, J Visser, JL Susante, CJ Loon |
Acta Orthopaedica | 2018 |
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Is the Enzyme-linked Immunosorbent Assay More Accurate Than the Lateral Flow Alpha Defensin Test for Diagnosing Periprosthetic Joint Infection?:
IK Sigmund, K Yermak, C Perka, A Trampuz, N Renz |
Clinical Orthopaedics and Related Research® | 2018 |
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G.I. pros: Antimicrobial defense in the gastrointestinal tract
LK Chung, M Raffatellu |
Seminars in Cell & Developmental Biology | 2018 |
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Genomic Structure and Tissue Expression of the NK-Lysin Gene Family in Bison
MO Lee, L Dobson, BW Davis, L Skow, J Derr, JE Womack |
Journal of Heredity | 2018 |
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Human β-defensin-1: A natural antimicrobial peptide present in amniotic fluid that is increased in spontaneous preterm labor with intra-amniotic infection
A Varrey, R Romero, B Panaitescu, D Miller, T Chaiworapongsa, M Patwardhan, J Faro, P Pacora, SS Hassan, CD Hsu, N Gomez-Lopez |
American Journal of Reproductive Immunology | 2018 |
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Host defense peptides: An insight into the antimicrobial world
S Gupta, G Bhatia, A Sharma, S Saxena |
Journal of Oral and Maxillofacial Pathology : JOMFP | 2018 |
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Qualitative Alpha-defensin Versus The Main Available Tests For The Diagnosis Of Periprosthetic Joint Infection: Best Predictor Test?
G Riccio, L Cavagnaro, W Akkouche, G Carrega, L Felli, G Burastero |
Journal of Bone and Joint Infection | 2018 |
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Recent updates of marine antimicrobial peptides
MH Semreen, MI El-Gamal, S Abdin, H Alkhazraji, L Kamal, S Hammad, F El-Awady, D Waleed, L Kourbaj |
Saudi Pharmaceutical Journal | 2018 |
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Management of Infections in the Immunocompromised Host
BH Segal |
2018 | |
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The terminal complement pathway is activated in septic but not in aseptic shoulder revision arthroplasties
AK Meinshausen, N Märtens, A Berth, J Färber, F Awiszus, P Macor, CH Lohmann, J Bertrand |
Journal of Shoulder and Elbow Surgery | 2018 |
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Synovial Fluid Alpha-Defensin Is an Adjunctive Tool in the Equivocal Diagnosis of Periprosthetic Joint Infection
MP Kelly, B Darrith, CP Hannon, D Nam, PM Courtney, CJ Valle |
The Journal of Arthroplasty | 2018 |
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Antibacterial properties of human beta defensin-3 derivative: CHRG01
A Arora, S Majhi, A Mishra |
Journal of Biosciences | 2018 |
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Human Antimicrobial Peptide Isolated From Triatoma infestans Haemolymph, Trypanosoma cruzi-Transmitting Vector
LC Diniz, A Miranda, |
Frontiers in Cellular and Infection Microbiology | 2018 |
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Did cis- and trans-defensins derive from a common ancestor?
W Zhou, B Gao, S Zhu |
Immunogenetics | 2018 |
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Identification of genetic risk factors of aggressive periodontitis using genomewide association studies in association with those of chronic periodontitis
R Masumoto, J Kitagaki, C Fujihara, M Matsumoto, S Miyauchi, Y Asano, A Imai, K Kobayashi, A Nakaya, M Yamashita, S Yamada, M Kitamura, S Murakami |
Journal of Periodontal Research | 2018 |
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Structural insight into the mechanism of action of antimicrobial peptide BMAP-28(1-18) and its analogue mutBMAP18
N Agadi, S Vasudevan, A Kumar |
Journal of Structural Biology | 2018 |
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Inflammatory disorders mimicking periprosthetic joint infections may result in false-positive α-defensin
A Plate, L Stadler, R Sutter, A Anagnostopoulos, D Frustaci, R Zbinden, SF Fucentese, AS Zinkernagel, PO Zingg, Y Achermann |
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases | 2018 |
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Synthesis of peptide–vinyl polymer multiblock hybrids by nitroxide-mediated polymerization: breaking the limitations of monomer compatibility
S Nishimura, N Higashi, T Koga |
Polymer Chemistry | 2018 |
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Low Plasma ADAMTS13 Activity Is Associated with Coagulopathy, Endothelial Cell Damage and Mortality after Severe Paediatric Trauma
R Russell, J McDaniel, W Cao, M Shroyer, B Wagener, X Zheng, JF Pittet |
Thrombosis and Haemostasis | 2018 |
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Update on Chlamydia trachomatis Vaccinology
LM de la Maza, G Zhong, RC Brunham, CJ Papasian |
Clinical and vaccine immunology : CVI | 2017 |
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The Role of Defensins in HIV Pathogenesis
BT Pace, AA Lackner, E Porter, B Pahar |
Mediators of Inflammation | 2017 |
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Alarmins and immunity
D Yang, Z Han, JJ Oppenheim |
Immunological Reviews | 2017 |
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Epithelial-mesenchymal transition and inflammation at the site of the primary tumor
C Dominguez, JM David, C Palena |
Seminars in Cancer Biology | 2017 |
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HIV-Enhancing and HIV-Inhibiting Properties of Cationic Peptides and Proteins.
Cole AM, Cole AL |
Viruses | 2017 |
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Snake Venoms
H Inagaki, CW Vogel, AK Mukherjee, TR Rahmy |
Snake Venoms | 2017 |
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Synthetic approaches to radiochemical probes for imaging of bacterial infections
J Dutta, T Naicker, T Ebenhan, HG Kruger, PI Arvidsson, T Govender |
European Journal of Medicinal Chemistry | 2017 |
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Clinical and Basic Immunodermatology
AA Gaspari, SK Tyring, DH Kaplan |
Clinical and Basic Immunodermatology | 2017 |
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Friends or Foes? Host defense (antimicrobial) peptides and proteins in human skin diseases
F Niyonsaba, C Kiatsurayanon, P Chieosilapatham, H Ogawa |
Experimental Dermatology | 2017 |
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Bioresources and Bioprocess in Biotechnology
S Sugathan, NS Pradeep, S Abdulhameed |
Bioresources and Bioprocess in Biotechnology | 2017 |
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Targeting and inactivation of bacterial toxins by human defensins
E Kudryashova, SM Seveau, DS Kudryashov |
Biological Chemistry | 2017 |
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Perspectives for clinical use of engineered human host defense antimicrobial peptides
ME Pachón-Ibáñez, Y Smani, J Pachón, J Sánchez-Céspedes |
FEMS Microbiology Reviews | 2017 |
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Pathogenesis of Periodontal Diseases
N Bostanci, GN Belibasakis |
Pathogenesis of Periodontal Diseases | 2017 |
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Defensins in Viral Infection and Pathogenesis
MK Holly, K Diaz, JG Smith |
Annual Review of Virology | 2017 |
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Variations in the interaction of human defensins with Escherichia coli: Possible implications in bacterial killing
B Mathew, R Nagaraj, K Zeth |
PloS one | 2017 |
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Comparative genomic identification and validation of β-defensin genes in the Ovis aries genome
TJ Hall, C McQuillan, EK Finlay, C OFarrelly, S Fair, KG Meade |
BMC Genomics | 2017 |
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Ubiquitous Nature of Fluoroquinolones: The Oscillation between Antibacterial and Anticancer Activities
T Idowu, F Schweizer |
Antibiotics | 2017 |
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Antimicrobial peptides as an alternative to anti-tuberculosis drugs
M AlMatar, EA Makky, G Yakıcı, I Var, B Kayar, F Köksal |
Pharmacological Research | 2017 |
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Small Bioactive Peptides for Biomaterials Design and Therapeutics
IW Hamley |
Chemical Reviews | 2017 |
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Surrogate Fecal Biomarkers in Inflammatory Bowel Disease: Rivals or Complementary Tools of Fecal Calprotectin?
MD Ruscio, F Vernia, A Ciccone, G Frieri, G Latella |
Inflammatory Bowel Diseases | 2017 |
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Targeting a cell wall biosynthesis hot spot
A Müller, A Klöckner, T Schneider |
Natural Product Reports | 2017 |
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Evolutionary Biology: Self/Nonself Evolution, Species and Complex Traits Evolution, Methods and Concepts
P Pontarotti |
2017 | |
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Synovial Fluid α-Defensin as a Biomarker for Peri-Prosthetic Joint Infection: A Systematic Review and Meta-Analysis
B Li, F Chen, Y Liu, G Xu |
Surgical Infections | 2017 |
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Expression of the zebrafish β-defensin 3 mature peptide in Pichia pastoris and its purification and antibacterial activity
Y Tao, CF Song, W Li |
Applied Biochemistry and Microbiology | 2017 |
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Role of Streptococcus mutans two-component systems in antimicrobial peptide resistance in the oral cavity
M Kawada-Matsuo, H Komatsuzawa |
The Japanese dental science review | 2017 |
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Associations between HBD3 and Pro-Inflammatory Cytokines in Asymptomatic Irreversible Pulpitis
A Aminoshariae, M Bakkar, T Bonfield, S Ghosh, TA Montagnese, AK Mickel |
2017 | |
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Granulopoiesis and granules of human neutrophils
JB Cowland, N Borregaard |
Immunological Reviews | 2016 |
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Interaction between antimicrobial peptides and mycobacteria
T Gutsmann |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 2016 |
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Antimicrobial peptides and wound healing: biological and therapeutic considerations
ML Mangoni, AM McDermott, M Zasloff |
Experimental Dermatology | 2016 |
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The role of antimicrobial peptides in chronic inflammatory skin diseases
M Marcinkiewicz, S Majewski |
POSTEP DERM ALERGOL | 2016 |
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Mammalian host defense peptides and their implication on combating Leishmania infection
Z Abdossamadi, N Seyed, S Rafati |
Cellular Immunology | 2016 |
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Alarmin human α defensin HNP1 activates plasmacytoid dendritic cells by triggering NF-κB and IRF1 signaling pathways
F Wang, L Qiao, X Lv, A Trivett, R Yang, JJ Oppenheim, D Yang, N Zhang |
Cytokine | 2016 |
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Polymorphisms in -Defensin-Encoding DEFA1A3 Associate with Urinary Tract Infection Risk in Children with Vesicoureteral Reflux
AL Schwaderer, H Wang, S Kim, JM Kline, D Liang, PD Brophy, KM McHugh, GC Tseng, V Saxena, E Barr-Beare, KR Pierce, N Shaikh, JR Manak, DM Cohen, B Becknell, JD Spencer, PB Baker, CY Yu, DS Hains |
Journal of the American Society of Nephrology : JASN | 2016 |
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Human beta-defensins 2 and -3 cointernalize with human immunodeficiency virus via heparan sulfate proteoglycans and reduce infectivity of intracellular virions in tonsil epithelial cells
R Herrera, M Morris, K Rosbe, Z Feng, A Weinberg, S Tugizov |
Virology | 2016 |
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Antimicrobial peptides as natural bio-preservative to enhance the shelf-life of food
M Rai, R Pandit, S Gaikwad, G Kövics |
Journal of Food Science and Technology | 2016 |
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Mechanisms and consequences of bacterial resistance to antimicrobial peptides
DI Andersson, D Hughes, JZ Kubicek-Sutherland |
Drug Resistance Updates | 2016 |
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Human neutrophil peptide-1 affects matrix metalloproteinase-2, -8 and -9 secretions of oral squamous cell carcinoma cell lines in vitro
AA Musrati, T Tervahartiala, M Gürsoy, E Könönen, D Fteita, T Sorsa, VJ Uitto, UK Gürsoy |
Archives of Oral Biology | 2016 |
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Effect of mutated defensin NP-1 on sciatic nerve regeneration after transection—A pivot study
C Xu, L Bai, Y Chen, C Fan, Z Hu, H Xu, B Jiang |
Neuroscience Letters | 2016 |
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The Defensins Consist of Two Independent, Convergent Protein Superfamilies
TM Shafee, FT Lay, MD Hulett, MA Anderson |
Molecular Biology and Evolution | 2016 |
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Fat body and hemocyte contribution to the antimicrobial peptide synthesis in Calliphora vicina R.-D. (Diptera: Calliphoridae) larvae
AY Yakovlev, AP Nesin, NP Simonenko, NA Gordya, DV Tulin, AA Kruglikova, SI Chernysh |
In vitro cellular & developmental biology. Animal | 2016 |
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Sequential and Structural Aspects of Antifungal Peptides from Animals, Bacteria and Fungi Based on Bioinformatics Tools
Neelabh, K Singh, J Rani |
Probiotics and Antimicrobial Proteins | 2016 |
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Molecular detection of intrauterine microbial colonization in women with endometriosis
KN Khan, A Fujishita, H Masumoto, H Muto, M Kitajima, H Masuzaki, J Kitawaki |
European Journal of Obstetrics & Gynecology and Reproductive Biology | 2016 |
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CORR Insights®: The Alpha-defensin Test for Periprosthetic Joint Infection is Not Affected by Prior Antibiotic Administration
MJ Spangehl |
Clinical Orthopaedics and Related Research® | 2016 |
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Reduction Impairs the Antibacterial Activity but Benefits the LPS Neutralization Ability of Human Enteric Defensin 5
C Wang, M Shen, N Zhang, S Wang, Y Xu, S Chen, F Chen, K Yang, T He, A Wang, Y Su, T Cheng, J Zhao, J Wang |
Scientific Reports | 2016 |
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Elevated Concentration of Defensins in Hepatitis C Virus-Infected Patients
EH Mattar, HA Almehdar, AA AlJaddawi, IE Zeid, EM Redwan |
Journal of Immunology Research | 2016 |
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Salivary antimicrobial defensins in pregnancy
M Gürsoy, UK Gürsoy, A Liukkonen, T Kauko, S Penkkala, E Könönen |
Journal of Clinical Periodontology | 2016 |
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Towards a paradigm shift in innate immunity—seminal work by Hans G. Boman and co-workers
I Faye, BG Lindberg |
Philosophical Transactions of the Royal Society B: Biological Sciences | 2016 |
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Antimicrobial and antiviral effects of human defensins: pathogenetic value and prospective application to medicinal therapy
VI Vaschenko, VN Vilyaninov, PD Shabanov |
Review on Clinical Pharmacology and Medicinal Therapy | 2016 |
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Chemistry of Antibiotics and Related Drugs
MK Bhattacharjee |
Chemistry of Antibiotics and Related Drugs | 2016 |
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Bactericidal Hydrogels via Surface Functionalization with Cecropin A
MA Cole, TF Scott, CM Mello |
ACS Biomaterials Science & Engineering | 2016 |
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Novel Insight Into the Role of Antimicrobial (Host Defense) Peptides/Proteins in Human Skin Diseases
F Niyonsaba |
Juntendo Medical Journal | 2016 |
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Bacterial membrane binding and pore formation abilities of carbohydrate recognition domain of fish lectin
A Arasu, V Kumaresan, R Palanisamy, MV Arasu, NA Al-Dhabi, MR Ganesh, J Arockiaraj |
Developmental & Comparative Immunology | 2016 |
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Advances in Experimental Medicine and Biology
O Borens, PS Corona, L Frommelt, S Lazarinis, MR Reed, CL Romano |
Advances in experimental medicine and biology | 2016 |
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Establishing a reference array for the CS-αβ superfamily of defensive peptides
DE Tarr |
BMC Research Notes | 2016 |
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The role of human β-defensins in allergic diseases
F Niyonsaba, C Kiatsurayanon, H Ogawa |
Clinical & Experimental Allergy | 2016 |
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Characterization of the antimicrobial peptide family defensins in the Tasmanian devil (Sarcophilus harrisii), koala (Phascolarctos cinereus), and tammar wallaby (Macropus eugenii)
EA Jones, Y Cheng, D OMeally, K Belov |
Immunogenetics | 2016 |
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Zinc induces LPS-mediated upregulation of HBD-2 via ERK1/2 and p38MAPK signaling pathways in human prostate epithelial cells
MS Kim, K Ko, HJ Kim, J Lee, SC Myung |
Animal Cells and Systems | 2016 |
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MicroRNA-orchestrated pathophysiologic control in gut homeostasis and inflammation
Juneyoung Lee, Eun Jeong Park, Hiroshi Kiyono |
BMB Reports | 2016 |
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Low concentrations of human neutrophil peptide ameliorate experimental murine colitis
T Maeda, T Sakiyama, S Kanmura, S Hashimoto, K Ibusuki, S Tanoue, Y Komaki, S Arima, Y Nasu, F Sasaki, H Taguchi, M Numata, H Uto, H Tsubouchi, A Ido |
International journal of molecular medicine | 2016 |
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Advancements in Diagnosing Periprosthetic Joint Infections after Total Hip and Knee Arthroplasty
R Patel, P Alijanipour, J Parvizi |
The open orthopaedics journal | 2016 |
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Laser-activated transforming growth factor-β1 induces human β-defensin 2: implications for laser therapies for periodontitis and peri-implantitis
E Tang, I Khan, S Andreana, PR Arany |
Journal of Periodontal Research | 2016 |
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CORR Insights®: How Reliable Is the Alpha-Defensin Immunoassay Test for Diagnosing Periprosthetic Joint Infection? A Prospective Study
TW Bauer |
Clinical Orthopaedics and Related Research® | 2016 |
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CORR Insights®: How Reliable Is the Alpha-Defensin Immunoassay Test for Diagnosing Periprosthetic Joint Infection? A Prospective Study
TW Bauer |
Clinical Orthopaedics and Related Research® | 2016 |
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Host Defense Peptides and Their Potential as Therapeutic Agents
RM Epand |
2016 | |
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Innate Antibacterial Activity in Female Genital Tract Secretions Is Associated with Increased Risk of HIV Acquisition
RP Madan, L Masson, J Tugetman, L Werner, A Grobler, K Mlisana, Y Lo, D Che, KB Arnold, SS Karim, JA Passmore, BC Herold |
AIDS Research and Human Retroviruses | 2015 |
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Processing of Neutrophil α-Defensins Does Not Rely on Serine Proteases In Vivo
A Glenthøj, K Nickles, J Cowland, N Borregaard, D Hartl |
PloS one | 2015 |
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The Potential Use of Natural and Structural Analogues of Antimicrobial Peptides in the Fight against Neglected Tropical Diseases
L Angélique, W Frederik, J Garmi, D Hester |
Molecules (Basel, Switzerland) | 2015 |
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Diverse functions of defensins and other antimicrobial peptides in periodontal tissues
H Dommisch, S Jepsen |
Periodontology 2000 | 2015 |
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Antimicrobial Peptides in Human Sepsis
L Martin, A Meegern, S Doemming, T Schuerholz |
Frontiers in immunology | 2015 |
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Antimicrobial potentials and structural disorder of human and animal defensins
EH Mattar, HA Almehdar, HA Yacoub, VN Uversky, EM Redwan |
Cytokine & Growth Factor Reviews | 2015 |
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Now you see me, now you don't: the interaction of Salmonella with innate immune receptors
AM Keestra-Gounder, RM Tsolis, AJ Bäumler |
Nature Reviews Microbiology | 2015 |
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Peptides and Peptidomimetics for Antimicrobial Drug Design
B Mojsoska, H Jenssen |
Pharmaceuticals (Basel, Switzerland) | 2015 |
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Calprotectin Increases the Activity of the SaeRS Two Component System and Murine Mortality during Staphylococcus aureus Infections
H Cho, DW Jeong, Q Liu, WS Yeo, T Vogl, EP Skaar, WJ Chazin, T Bae, FR DeLeo |
PLoS pathogens | 2015 |
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Antimicrobial peptides and peptidomimetics - potent therapeutic allies for staphylococcal infections.
Mohammad H, Thangamani S, Seleem MN |
Current pharmaceutical design | 2015 |
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Human β-defensin-3 increases the expression of interleukin-37 through CCR6 in human keratinocytes
R Smithrithee, F Niyonsaba, C Kiatsurayanon, H Ushio, S Ikeda, K Okumura, H Ogawa |
Journal of Dermatological Science | 2015 |
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The Alpha-defensin Test for Periprosthetic Joint Infection Responds to a Wide Spectrum of Organisms
C Deirmengian, K Kardos, P Kilmartin, S Gulati, P Citrano, RE Booth |
Clinical Orthopaedics and Related Research® | 2015 |
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Mechanisms of group A Streptococcus resistance to reactive oxygen species
A Henningham, S Dohrmann, V Nizet, JN Cole |
FEMS Microbiology Reviews | 2015 |
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Biologically Active and Antimicrobial Peptides from Plants
CE Salas, JA Badillo-Corona, G Ramírez-Sotelo, C Oliver-Salvador |
BioMed Research International | 2015 |
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Oral Antimicrobial Peptides: Types and Role in the Oral Cavity
Z Khurshid, M Naseem, Z Sheikh, S Najeeb, S Shahab, MS Zafar |
Saudi Pharmaceutical Journal | 2015 |
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The new insights into the oyster antimicrobial defense: Cellular, molecular and genetic view
E Bachère, RD Rosa, P Schmitt, AC Poirier, N Merou, GM Charrière, D Destoumieux-Garzón |
Fish & Shellfish Immunology | 2015 |
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An Evolutionary History of Defensins: A Role for Copy Number Variation in Maximizing Host Innate and Adaptive Immune Responses
LR Machado, B Ottolini |
Frontiers in immunology | 2015 |
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Mass spectral analysis of urine proteomic profiles of dairy cows suffering from clinical ketosis
C Xu, S Shu, C Xia, P Wang, Y Sun, C Xu, C Li |
Veterinary Quarterly | 2015 |
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RNA-seq Transcriptional Profiling of an Arbuscular Mycorrhiza Provides Insights into Regulated and Coordinated Gene Expression in Lotus japonicus and Rhizophagus irregularis
Y Handa, H Nishide, N Takeda, Y Suzuki, M Kawaguchi, K Saito |
Plant and Cell Physiology | 2015 |
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The Frog Skin-Derived Antimicrobial Peptide Esculentin-1a(1-21)NH2 Promotes the Migration of Human HaCaT Keratinocytes in an EGF Receptor-Dependent Manner: A Novel Promoter of Human Skin Wound Healing?
AD Grazia, F Cappiello, A Imanishi, A Mastrofrancesco, M Picardo, R Paus, ML Mangoni, J Harder |
PloS one | 2015 |
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Molecular Medical Microbiology
M Reglinski, S Sriskandan |
2015 | |
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Foldamers as Anticancer Therapeutics: Targeting Protein-Protein Interactions and the Cell Membrane
S Fahs, Y Patil-Sen, TJ Snape |
ChemBioChem | 2015 |
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Antimicrobial activity of human α-defensin 5 and its linear analogs: N-terminal fatty acylation results in enhanced antimicrobial activity of the linear analogs
B Mathew, R Nagaraj |
Peptides | 2015 |
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In Vitro Studies on the Antimicrobial Peptide Human Beta-Defensin 9 (HBD9): Signalling Pathways and Pathogen-Related Response (An American Ophthalmological Society Thesis)
Harminder S Dua, Ahmad Muneer Otri, Andrew Hopkinson, Imran Mohammed |
Transactions of the American Ophthalmological Society | 2015 |
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Peptide Chemistry and Drug Design: Dunn/Peptide Chemistry and Drug Design
JT Nguyen, Y Kiso |
Peptide Chemistry and Drug Design: Dunn/Peptide Chemistry and Drug Design | 2015 |
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Activity of Genital Tract Secretions and Synthetic Antimicrobial Peptides against Group B Streptococcus
N Agarwal, N Buckley, N Nakra, P Gialanella, W Yuan, JP Ghartey |
American Journal of Reproductive Immunology | 2015 |
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Plasma α-defensins are elevated during exacerbation of atopic dermatitis
NN Tsybikov, IV Petrisheva, EV Fefelova, BI Kuznik, E Magen |
Clinical and Experimental Dermatology | 2015 |
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Antimicrobial activity of human α-defensin 6 analogs: insights into the physico-chemical reasons behind weak bactericidal activity of HD6 in vitro: Analogs of Human Defensin HD6 Show Antibacterial Activity
B Mathew, R Nagaraj |
Journal of Peptide Science | 2015 |
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PPARα agonists inhibit inflammatory activation of macrophages through upregulation of β-defensin 1
S Ann, JH Chung, BH Park, SH Kim, J Jang, S Park, SM Kang, SH Lee |
Atherosclerosis | 2015 |
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An intimate link between antimicrobial peptide sequence diversity and binding to essential components of bacterial membranes
P Schmitt, RD Rosa, D Destoumieux-Garzón |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 2015 |
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Antimicrobial Proteins and Peptides in Human Lung Diseases: A Friend and Foe Partnership with Host Proteases
F Lecaille, G Lalmanach, PM Andrault |
Biochimie | 2015 |
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Optimized Expression and Characterization of Antimicrobial Peptides, LPcin Analogs: Expression and Characterization of Antimicrobial Peptides
JS Kim, JH Jeong, KS Kim, Y Kim |
Bulletin of the Korean Chemical Society | 2015 |
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Salivary Antimicrobial Peptides in Early Detection of Periodontitis
GN Güncü, D Yilmaz, E Könönen, UK Gürsoy |
Frontiers in Cellular and Infection Microbiology | 2015 |
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Rhesus macaque -defensin RTD-1 inhibits proinflammatory cytokine secretion and gene expression by inhibiting the activation of NF- B and MAPK pathways
P Tongaonkar, KK Trinh, JB Schaal, D Tran, PS Gulko, AJ Ouellette, ME Selsted |
Journal of leukocyte biology | 2015 |
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Diet and Nutrition in Critical Care
D Youssef, K Amrein, C Schnedl, H Dobnig, AN Peiris |
Diet and Nutrition in Critical Care | 2015 |
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Biomaterials in Regenerative Medicine and the Immune System
L Santambrogio |
2015 | |
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Complexity of antimicrobial peptide regulation during pathogen–host interactions
GM Wassing, P Bergman, L Lindbom, AM van der Does |
International Journal of Antimicrobial Agents | 2014 |
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Functional intersection of Human Defensin 5 with the TNF receptor pathway
W Lu, E Leeuw |
FEBS Letters | 2014 |
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Defensins: antifungal lessons from eukaryotes
PM Silva, S Gonçalves, NC Santos |
Frontiers in microbiology | 2014 |
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ProHNPs are specific markers of normal myelopoiesis
F Emmertsen, A Glenthøj, J Sønderskov, P Kampmann, H Sengeløv, N Borregaard |
Blood Cancer Journal | 2014 |
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Innate Immunity to Adenovirus
R Hendrickx, N Stichling, J Koelen, L Kuryk, A Lipiec, UF Greber |
Human Gene Therapy | 2014 |
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High-quality 3D structures shine light on antibacterial, anti-biofilm and antiviral activities of human cathelicidin LL-37 and its fragments
G Wang, B Mishra, RF Epand, RM Epand |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 2014 |
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Ultrastructural immunocytochemistry suggests that periderm granules in embryonic chick epidermis contain beta-defensins
L Alibardi |
Acta Histochemica | 2014 |
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Herpes Simplex epithelial keratitis associated with daily disposable contact lens wear
A Hamroush, J Welch |
Contact Lens and Anterior Eye | 2014 |
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Functional intersection of Human Defensin 5 with the TNF receptor pathway
W Lu, E Leeuw |
FEBS Letters | 2014 |
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Defensins are natural peptide antibiotics of higher eukaryotes
DV Grishin, NN Sokolov |
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry | 2014 |
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Induction of human defensins by intestinal Caco-2 cells after interactions with opportunistic Candida species
A Gácser, Z Tiszlavicz, T Németh, G Seprényi, Y Mándi |
Microbes and Infection | 2014 |
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The Alpha-defensin Test for Periprosthetic Joint Infection Outperforms the Leukocyte Esterase Test Strip
C Deirmengian, K Kardos, P Kilmartin, A Cameron, K Schiller, RE Booth, J Parvizi |
Clinical Orthopaedics and Related Research® | 2014 |
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Membrane Disruptive antimicrobial activities of human β-defensin-3 analogs
US Sudheendra, V Dhople, A Datta, RK Kar, CE Shelburne, A Bhunia, A Ramamoorthy |
European Journal of Medicinal Chemistry | 2014 |
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Inferring mechanisms of copy number change from haplotype structures at the human DEFA1A3 locus
HA Black, FF Khan, J Tyson, JA Armour |
BMC Genomics | 2014 |
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Discovery of modulators of HIV-1 infection from the human peptidome
J Münch, L Ständker, WG Forssmann, F Kirchhoff |
Nature Reviews Microbiology | 2014 |
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Molecular Evolution of the Primate α-/θ-Defensin Multigene Family
DQ Cheng, Y Li, JF Huang, AM Cole |
PloS one | 2014 |
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Antimicrobial Peptides from Fish
JA Masso-Silva, G Diamond |
Pharmaceuticals (Basel, Switzerland) | 2014 |
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Modulation of Antimicrobial Peptide Human β-defensin-3 by Toll-like Receptor Ligands in Vaginal Epithelial Cells
SY Lee, H Kim, IH Chang, JH Han, KD Kim, YT Moon, SC Myung |
The Korean Journal of Urogenital Tract Infection and Inflammation | 2014 |
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Utilization of plant-derived recombinant human β-defensins (hBD-1 and hBD-2) for averting salmonellosis
S Patro, S Maiti, SK Panda, N Dey |
Transgenic Research | 2014 |
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Inhibition of Pseudomonas aeruginosa with a recombinant RNA-based viral vector expressing human β-defensin 4
S Park, J Kim, I Lee, JY Bae, MW Hwang, D Kim, SI Jang, H Kim, M Park, HJ Kwon, JW Song, Y Cho, W Chun, MS Park |
BMC Microbiology | 2014 |
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Insight into the impact of environments on structure of chimera C3 of human β-defensins 2 and 3 from molecular dynamics simulations
Q Li, H Yu, X Zhao, X Huang |
Journal of Biomolecular Structure and Dynamics | 2014 |
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Altered α -defensin 5 expression in cervical squamocolumnar junction: implication in the formation of a viral/tumour-permissive microenvironment: Altered α-defensin 5 expression in squamocolumnar junction
P Hubert, L Herman, P Roncarati, C Maillard, V Renoux, S Demoulin, C Erpicum, JM Foidart, J Boniver, A Noël, P Delvenne, M Herfs |
The Journal of Pathology | 2014 |
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Microbial biofilms: biosurfactants as antibiofilm agents
IM Banat, MA de Rienzo, GA Quinn |
Applied Microbiology and Biotechnology | 2014 |
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Epithelial Antimicrobial Peptides: Guardian of the Oral Cavity
M Hans, VM Hans |
International Journal of Peptides | 2014 |
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The Transcriptomic and Proteomic Landscapes of Bone Marrow and Secondary Lymphoid Tissues
S Andersson, K Nilsson, L Fagerberg, BM Hallström, C Sundström, A Danielsson, K Edlund, M Uhlen, A Asplund, P Rameshwar |
PloS one | 2014 |
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Hydrophobic Determinants of -Defensin Bactericidal Activity
KP Tai, VV Le, ME Selsted, AJ Ouellette |
Infection and immunity | 2014 |
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Isotretinoin therapy changes the expression of antimicrobial peptides in acne vulgaris
A Borovaya, Y Dombrowski, S Zwicker, O Olisova, T Ruzicka, R Wolf, J Schauber, M Sárdy |
Archives of Dermatological Research | 2014 |
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Joint Replacement Technology
A Nair, DW Baker, L Tang |
Joint Replacement Technology | 2014 |
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Effective Control of Salmonella Infections by Employing Combinations of Recombinant Antimicrobial Human -Defensins hBD-1 and hBD-2
S Maiti, S Patro, S Purohit, S Jain, S Senapati, N Dey |
Antimicrobial agents and chemotherapy | 2014 |
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Antimycobacterial activity of Pichia pastoris-derived mature bovine neutrophil β-defensins 5
J Kang, D Zhao, Y Lyu, L Tian, X Yin, L Yang, K Teng, X Zhou |
European Journal of Clinical Microbiology & Infectious Diseases | 2014 |
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A novel subclass of bovine β-defensins links reproduction and immunology
F Narciandi, A Lloyd, KG Meade, C O'Farrelly |
Reproduction, Fertility and Development | 2014 |
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Intra-uterine microbial colonization and occurrence of endometritis in women with endometriosis
KN Khan, A Fujishita, M Kitajima, K Hiraki, M Nakashima, H Masuzaki |
Human Reproduction | 2014 |
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Human neutrophil peptide 1-3, a component of the neutrophil extracellular trap, as a potential biomarker of lupus nephritis
FJ Cheng, XJ Zhou, YF Zhao, MH Zhao, H Zhang |
International Journal of Rheumatic Diseases | 2014 |
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Innate Immunity of the Epidermis (2) :: Antimicrobial Peptide Derived from Human Keratinocytes
M MURAKAMI, K SAYAMA |
Nishi Nihon Hifuka | 2014 |
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Novel Anti-Microbial Peptide SR-0379 Accelerates Wound Healing via the PI3 Kinase/Akt/mTOR Pathway
H Tomioka, H Nakagami, A Tenma, Y Saito, T Kaga, T Kanamori, N Tamura, K Tomono, Y Kaneda, R Morishita, GC Jagetia |
PloS one | 2014 |
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Bovine β-defensin gene family: opportunities to improve animal health?
KG Meade, P Cormican, F Narciandi, A Lloyd, C O'Farrelly |
Physiological genomics | 2014 |
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Defensins – natural peptide antibiotics of higher eucariotes
DV Grishin, NN Sokolov |
Biomeditsinskaya Khimiya | 2014 |
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Antimycobacterial activity of Pichia pastoris-derived mature bovine neutrophil β-defensins 5.
Kang J, Zhao D, Lyu Y, Tian L, Yin X, Yang L, Teng K, Zhou X |
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology | 2014 |
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Cationic host defence peptides: potential as antiviral therapeutics
EG Findlay, SM Currie, DJ Davidson |
BioDrugs | 2013 |
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Antiviral Mechanisms of Human Defensins
SS Wilson, ME Wiens, JG Smith |
Journal of Molecular Biology | 2013 |
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Single, double and quadruple alanine substitutions at oligomeric interfaces identify hydrophobicity as the key determinant of human neutrophil alpha defensin HNP1 function
L Zhao, WD Tolbert, B Ericksen, C Zhan, X Wu, W Yuan, X Li, M Pazgier, W Lu |
PloS one | 2013 |
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Probiotics, Prebiotics and Immunomodulation of Gut Mucosal Defences: Homeostasis and Immunopathology
H Hardy, J Harris, E Lyon, J Beal, A Foey |
Nutrients | 2013 |
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The Drosophila IMD pathway in the activation of the humoral immune response
A Kleino, N Silverman |
Developmental & Comparative Immunology | 2013 |
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Assays optimized for detection and quantification of antibacterial activity in shark cell lysates under high salt conditions
SL Smith, NH Vaughan |
Fish & Shellfish Immunology | 2013 |
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Granulocytes of reptilian sauropsids contain beta-defensin-like peptides: A comparative ultrastructural survey: Beta-Defensins in Reptilian Granulocytes
L Alibardi |
Journal of Morphology | 2013 |
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ProHNPs are the principal α-defensins of human plasma
A Glenthøj, AJ Glenthøj, N Borregaard |
European Journal of Clinical Investigation | 2013 |
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Defensins: Natural component of human innate immunity
J Jarczak, EM Kościuczuk, P Lisowski, N Strzałkowska, A Jóźwik, J Horbańczuk, J Krzyżewski, L Zwierzchowski, E Bagnicka |
Human Immunology | 2013 |
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Localization of the anti-cancer peptide EGFR-lytic hybrid peptide in human pancreatic cancer BxPC-3 cells by immunocytochemistry: LOCALIZATION OF EGFR-LYTIC PEPTIDE IN BXPC-3 CELLS BY IMMUNOSTAIN
K Ohara, M Kohno, K Kawakami |
Journal of Peptide Science | 2013 |
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Mouse Paneth cell antimicrobial function is independent of Nod2
MT Shanahan, IM Carroll, E Grossniklaus, A White, RJ von Furstenberg, R Barner, AA Fodor, SJ Henning, RB Sartor, AS Gulati |
Gut | 2013 |
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Structure of the polypeptide crotamine from the Brazilian rattlesnake Crotalus durissus terrificus
MA Coronado, A Gabdulkhakov, D Georgieva, B Sankaran, MT Murakami, RK Arni, C Betzel |
Acta Crystallographica Section D Biological Crystallography | 2013 |
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Characterization of Antimicrobial Peptides toward the Development of Novel Antibiotics
W Aoki, M Ueda |
Pharmaceuticals (Basel, Switzerland) | 2013 |
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Current scenario of peptide-based drugs: the key roles of cationic antitumor and antiviral peptides
KC Mulder, LA Lima, VJ Miranda, SC Dias, OL Franco |
Frontiers in microbiology | 2013 |
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Antifungal proteins: More than antimicrobials?
N Hegedüs, F Marx |
Fungal Biology Reviews | 2013 |
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The human antimicrobial peptide LL-37, but not the mouse ortholog, mCRAMP, can stimulate signaling by poly(I:C) through a FPRL1-dependent pathway
D Singh, R Qi, JL Jordan, LS Mateo, CC Kao |
The Journal of biological chemistry | 2013 |
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Neutrophils: Neglected Players in Viral Diseases
C Gabriel, Z Her, LF Ng |
DNA and Cell Biology | 2013 |
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Neutrophils and emerging targets for treatment in chronic obstructive pulmonary disease
M Meijer, GT Rijkers, FJ van Overveld |
Expert Review of Clinical Immunology | 2013 |
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An optimized Fmoc synthesis of human defensin 5
E Vernieri, J Valle, D Andreu, BG de la Torre |
Amino Acids | 2013 |
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Host defense peptides: general overview and an update on their activity against Chlamydia spp
AD Francesco, A Favaroni, M Donati |
Expert Review of Anti-infective Therapy | 2013 |
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An innovative biologic recycling process of leukoreduction filters to produce active human antimicrobial peptides: Innovative production of active HNPs 1 to 3
L Vossier, F Leon, C Bachelier, H Marchandin, S Lehmann, JP Leonetti, K Brodolin, J Coste, C Fournier-Wirth |
Transfusion | 2013 |
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Entry of a cationic lytic-type peptide into the cytoplasm via endocytosis-dependent and -independent pathways in human glioma U251 cells
K Ohara, M Kohno, T Hamada, K Kawakami |
Peptides | 2013 |
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Integration of defensins: a promising clinical tool
P Singh |
International journal of preventive medicine | 2013 |
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Antimicrobial peptides and colitis
S Ho, C Pothoulakis, HW Koon |
Current pharmaceutical design | 2013 |
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The role of gut microbiota in programming the immune phenotype
M Weng, WA Walker |
Journal of Developmental Origins of Health and Disease | 2013 |
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Microbicidal effects of - and -defensins against antibiotic-resistant Staphylococcus aureus and Pseudomonas aeruginosa
KP Tai, K Kamdar, J Yamaki, VV Le, D Tran, P Tran, ME Selsted, AJ Ouellette, A Wong-Beringer |
Innate immunity | 2013 |
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Single, Double and Quadruple Alanine Substitutions at Oligomeric Interfaces Identify Hydrophobicity as the Key Determinant of Human Neutrophil Alpha Defensin HNP1 Function
L Zhao, WD Tolbert, B Ericksen, C Zhan, X Wu, W Yuan, X Li, M Pazgier, W Lu, G Maga |
PloS one | 2013 |
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Cellular Response to Trypanosoma cruzi Infection Induces Secretion of Defensin α-1, Which Damages the Flagellum, Neutralizes Trypanosome Motility, and Inhibits Infection
CA Johnson, G Rachakonda, YY Kleshchenko, PN Nde, MN Madison, S Pratap, TC Cardenas, C Taylor, MF Lima, F Villalta, JF Urban |
Infection and immunity | 2013 |
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Nasal Physiology and Pathophysiology of Nasal Disorders
TM Önerci |
2013 | |
|
2-Arachidonoyl-glycerol- and arachidonic acid-stimulated neutrophils release antimicrobial effectors against E. coli, S. aureus, HSV-1, and RSV
F Chouinard, C Turcotte, X Guan, MC Larose, S Poirier, L Bouchard, V Provost, L Flamand, N Grandvaux, N Flamand |
Journal of leukocyte biology | 2012 |
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Tissue-specific human beta-defensins (HBD)-1, HBD-2 and HBD-3 secretion profile from human amniochorionic membranes stimulated with Candida albicans in a two-compartment tissue culture system
V Zaga-Clavellina, M Ruiz, P Flores-Espinosa, R Vega-Sanchez, A Flores-Pliego, G Estrada-Gutierrez, I Sosa-Gonzalez, I Morales-Méndez, M Osorio-Caballero |
Reproductive Biology and Endocrinology | 2012 |
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Azurophil Granule Proteins Constitute the Major Mycobactericidal Proteins in Human Neutrophils and Enhance the Killing of Mycobacteria in Macrophages
P Jena, S Mohanty, T Mohanty, S Kallert, M Morgelin, T Lindstrøm, N Borregaard, S Stenger, A Sonawane, OE Sørensen |
PloS one | 2012 |
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Interleukin-6 Induces S100A9 Expression in Colonic Epithelial Cells through STAT3 Activation in Experimental Ulcerative Colitis
MJ Lee, JK Lee, JW Choi, CS Lee, JH Sim, CH Cho, KH Lee, IH Cho, MH Chung, HR Kim, SK Ye, DL Boone |
PloS one | 2012 |
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The Antimicrobial Defense of the Pacific Oyster, Crassostrea gigas. How Diversity may Compensate for Scarcity in the Regulation of Resident/Pathogenic Microflora
P Schmitt, RD Rosa, M Duperthuy, J Lorgeril, E Bachère, D Destoumieux-Garzón |
Frontiers in microbiology | 2012 |
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Antimicrobial peptide defensin: Identification of novel isoforms and the characterization of their physiological roles and their significance in the pathogenesis of diseases
Y Yamaguchi, Y Ouchi |
Proceedings of the Japan Academy. Series B, Physical and biological sciences | 2012 |
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Recombinant human beta 2-defensin fusion proteins as a tool to investigate defensin structure and function in small human intestinal tissue samples
A Coordes, A Andreou, U Erben, T Stroh, K Blunert, N Slavova, B Siegmund, HJ Buhr, AJ Kroesen |
Inflammation Research | 2012 |
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Methods in Enzymology
JD Stone, AS Chervin, DH Aggen, DM Kranz |
Protein Engineering for Therapeutics Part B | 2012 |
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LL37 and hBD-3 elevate the β-1,3-exoglucanase activity of <i>Candida albicans</i> Xog1p, resulting in reduced fungal adhesion to plastic
HT Chang, PW Tsai, HH Huang, YS Liu, TS Chien, CY Lan |
Biochemical Journal | 2012 |
|
Human Neutrophil Defensins and Their Effect on Epithelial Cells
UK Gursoy, E Könönen, N Luukkonen, VJ Uitto |
Journal of Periodontology | 2012 |
|
Physiology of the Gastrointestinal Tract, Two Volume Set
PR Kiela, JF Collins, FK Ghishan |
Physiology of the Gastrointestinal Tract, Two Volume Set | 2012 |
|
Next generation of antimicrobial peptides as molecular targeted medicines
W Aoki, K Kuroda, M Ueda |
Journal of Bioscience and Bioengineering | 2012 |
|
Antimicrobial activity of human β-defensin 4 analogs: insights into the role of disulfide linkages in modulating activity
H Sharma, R Nagaraj |
Peptides | 2012 |
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Construction of recombinant E. coli Nissle 1917 (EcN) strains for the expression and secretion of defensins
E Seo, S Weibel, J Wehkamp, TA Oelschlaeger |
International Journal of Medical Microbiology | 2012 |
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Lipopeptide biosurfactants from Paenibacillus polymyxa inhibit single and mixed species biofilms
GA Quinn, AP Maloy, S McClean, B Carney, JW Slater |
Biofouling | 2012 |
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Functional determinants of human enteric α-defensin HD5: crucial role for hydrophobicity at dimer interface
M Rajabi, B Ericksen, X Wu, E Leeuw, L Zhao, M Pazgier, W Lu |
The Journal of biological chemistry | 2012 |
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Dimerization of plant defensin NaD1 enhances its antifungal activity
FT Lay, GD Mills, IK Poon, NP Cowieson, N Kirby, AA Baxter, NL van der Weerden, C Dogovski, MA Perugini, MA Anderson, M Kvansakul, MD Hulett |
The Journal of biological chemistry | 2012 |
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Invariant gly residue is important for α-defensin folding, dimerization, and function: a case study of the human neutrophil α-defensin HNP1
L Zhao, B Ericksen, X Wu, C Zhan, W Yuan, X Li, M Pazgier, W Lu |
The Journal of biological chemistry | 2012 |
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Sometimes it takes two to tango: contributions of dimerization to functions of human α-defensin HNP1 peptide
M Pazgier, G Wei, B Ericksen, G Jung, Z Wu, E Leeuw, W Yuan, H Szmacinski, WY Lu, J Lubkowski, RI Lehrer, W Lu |
The Journal of biological chemistry | 2012 |
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Antibacterial Activity of Four Human Beta-Defensins: HBD-19, HBD-23, HBD-27, and HBD-29
BT Chow, M Soto, BL Lo, DC Crosby, D Camerini |
Polymers | 2012 |
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Peptidylarginine Deiminases Present in the Airways during Tobacco Smoking and Inflammation Can Citrullinate the Host Defense Peptide LL-37, Resulting in Altered Activities
O Kilsgård, P Andersson, M Malmsten, SL Nordin, HM Linge, M Eliasson, E Sörenson, JS Erjefält, J Bylund, AI Olin, OE Sørensen, A Egesten |
American journal of respiratory cell and molecular biology | 2012 |
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Human Defensins: Potential Tools for Clinical Applications
J Winter, M Wenghoefer |
Polymers | 2012 |
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Azurophil Granule Proteins Constitute the Major Mycobactericidal Proteins in Human Neutrophils and Enhance the Killing of Mycobacteria in Macrophages
P Jena, S Mohanty, T Mohanty, S Kallert, M Morgelin, T Lindstrøm, N Borregaard, S Stenger, A Sonawane, OE Sørensen, N Bovenschen |
PloS one | 2012 |
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Rhesus Macaque Theta Defensins Suppress Inflammatory Cytokines and Enhance Survival in Mouse Models of Bacteremic Sepsis
JB Schaal, D Tran, P Tran, G Ösapay, K Trinh, KD Roberts, KM Brasky, P Tongaonkar, AJ Ouellette, ME Selsted, J Zimmer |
PloS one | 2012 |
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Antimicrobial Peptides and Innate Immunity
PS Hiemstra, SA Zaat |
2012 | |
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Relative Spatial Positions of Tryptophan and Cationic Residues in Helical Membrane-active Peptides Determine Their Cytotoxicity
Ø Rekdal, BE Haug, M Kalaaji, HN Hunter, I Lindin, I Israelsson, T Solstad, N Yang, M Brandl, D Mantzilas, HJ Vogel |
The Journal of biological chemistry | 2012 |
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Human antimicrobial proteins in ear wax
M Schwaab, A Gurr, A Neumann, S Dazert, A Minovi |
European Journal of Clinical Microbiology & Infectious Diseases | 2011 |
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Dangers Within: DAMP Responses to Damage and Cell Death in Kidney Disease
DL Rosin, MD Okusa |
Journal of the American Society of Nephrology : JASN | 2011 |
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Kaposi's Sarcoma-Associated Herpesvirus Infection of Endothelial Cells Inhibits Neutrophil Recruitment through an Interleukin-6-Dependent Mechanism: a New Paradigm for Viral Immune Evasion
LM Butler, HC Jeffery, RL Wheat, PC Rae, K Townsend, KR Alkharsah, TF Schulz, GB Nash, DJ Blackbourn |
Journal of virology | 2011 |
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Protecting the boundary: the sentinel role of host defense peptides in the skin
JJ Bernard, RL Gallo |
Cellular and Molecular Life Sciences | 2011 |
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Antimicrobial peptides: Old Molecules with New Ideas
T Nakatsuji, RL Gallo |
Journal of Investigative Dermatology | 2011 |
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Innate Immunity in the Human Female Reproductive Tract: Endocrine Regulation of Endogenous Antimicrobial Protection Against HIV and Other Sexually Transmitted Infections
CR Wira, MV Patel, M Ghosh, L Mukura, JV Fahey |
American Journal of Reproductive Immunology | 2011 |
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Paneth cell α-defensins in enteric innate immunity
AJ Ouellette |
Cellular and Molecular Life Sciences | 2011 |
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Innate Immune System of Skin and Oral Mucosa
KE Burke, N Anandasabapathy |
Innate Immune System of Skin and Oral Mucosa | 2011 |
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Differential suppression of epidermal antimicrobial protein expression in atopic dermatitis and in EFAD mice by pimecrolimus compared to corticosteroids
JM Jensen, K Ahrens, J Meingassner, A Scherer, M Bräutigam, A Stütz, T Schwarz, R Fölster-Holst, J Harder, R Gläser, E Proksch |
Experimental Dermatology | 2011 |
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Cathelicidins—Therapeutic antimicrobial and antitumor host defense peptides for oral diseases
K Okumura |
Japanese Dental Science Review | 2011 |
|
Human β-defensin 3 (DEFB103) and its influence on Staphylococcus aureus nasal carriage
P Fode, M Stegger, PS Andersen |
International Journal of Infectious Diseases | 2011 |
|
Biological characteristics of defensin and its disease-resistance genetic engineering
LB FU, JL YU, WH LIU |
Hereditas (Beijing) | 2011 |
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Induction of Human -defensins and Psoriasin in Vulvovaginal Human Papillomavirus-Associated Lesions
W Erhart, O Alkasi, G Brunke, F Wegener, N Maass, N Arnold, A Arlt, I Meinhold-Heerlein |
The Journal of Infectious Diseases | 2011 |
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Growth-phase dependence of susceptibility to antimicrobial peptides in Staphylococcus aureus
M Matsuo, Y Oogai, F Kato, M Sugai, H Komatsuzawa |
Microbiology | 2011 |
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An antimicrobial protein, lactoferrin exists in the sweat: proteomic analysis of sweat
JH Park, GT Park, IH Cho, SM Sim, JM Yang, DY Lee |
Experimental Dermatology | 2011 |
|
Peptidome profiling of induced sputum by mesoporous silica beads and MALDI-TOF MS for non-invasive biomarker discovery of chronic inflammatory lung diseases
R Terracciano, M Preianò, GP Palladino, GE Carpagnano, MP Barbaro, G Pelaia, R Savino, R Maselli |
PROTEOMICS | 2011 |
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Human neutrophil peptide-1 aggravates dextran sulfate sodium-induced colitis
S Hashimoto, H Uto, S Kanmura, T Sakiyama, M Oku, Y Iwashita, R Ibusuki, F Sasaki, K Ibusuki, Y Takami, A Moriuchi, M Oketani, A Ido, H Tsubouchi |
Inflammatory Bowel Diseases | 2011 |
|
Antimicrobial peptides important in innate immunity : Antimicrobial peptides important in innate immunity
A Cederlund, GH Gudmundsson, B Agerberth |
FEBS Journal | 2011 |
|
Annual Reports in Medicinal Chemistry
JJ Liu, TW Lee |
Annual Reports in Medicinal Chemistry Volume 46 | 2011 |
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Wounding in lizards results in the release of beta-defensins at the wound site and formation of an antimicrobial barrier
L Alibardi, A Celeghin, LD Valle |
Developmental & Comparative Immunology | 2011 |
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Novel Anti-bacterial Activities of β-defensin 1 in Human Platelets: Suppression of Pathogen Growth and Signaling of Neutrophil Extracellular Trap Formation
BF Kraemer, RA Campbell, H Schwertz, MJ Cody, Z Franks, ND Tolley, WH Kahr, S Lindemann, P Seizer, CC Yost, GA Zimmerman, AS Weyrich |
PLoS pathogens | 2011 |
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Peptide polarity and the position of arginine as sources of selectivity during positive electrospray ionisation mass spectrometry : Peptide polarity and position of arginine as sources of selectivity
DA Abaye, FS Pullen, BV Nielsen |
Rapid Communications in Mass Spectrometry | 2011 |
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Intestinal defensin secretion in infancy is associated with the emergence of sensitization and atopic dermatitis
EM Savilahti, AK Kukkonen, T Haahtela, T Tuure, M Kuitunen, E Savilahti |
Clinical & Experimental Allergy | 2011 |
|
ACS Symposium Series
SF Peteu, S Banihani, MM Gunesekera, P Peiris, OA Sicuia, M Bayachou |
Oxidative Stress Diagnostics Prevention and Therapy | 2011 |
|
Antimicrobial Peptides
JF Marcos, P Manzanares |
Antimicrobial Polymers Lagaron/Antimicrobial Polymers | 2011 |
|
Proteinase 3 carries small unusual carbohydrates and associates with αlpha-defensins
MZ Hansen, T Ravnsborg, P Højrup, G Houen, C Schou |
Journal of Proteomics | 2011 |
|
α-Defensins in human innate immunity : α-Defensins
RI Lehrer, W Lu |
Immunological Reviews | 2011 |
|
Current Topics in Developmental Biology
JE Qualls, PJ Murray |
Cancer and Development | 2011 |
|
Identification and characterization of a novel cathelicidin from ayu, Plecoglossus altivelis
XJ Lu, J Chen, ZA Huang, YH Shi, JN Lυ¨ |
Fish & Shellfish Immunology | 2011 |
|
Novel Anti-bacterial Activities of β-defensin 1 in Human Platelets: Suppression of Pathogen Growth and Signaling of Neutrophil Extracellular Trap Formation
BF Kraemer, RA Campbell, H Schwertz, MJ Cody, Z Franks, ND Tolley, WH Kahr, S Lindemann, P Seizer, CC Yost, GA Zimmerman, AS Weyrich, FR DeLeo |
PLoS pathogens | 2011 |
|
HIV-1 Enhancing Effect of Prostatic Acid Phosphatase Peptides Is Reduced in Human Seminal Plasma
JA Martellini, AL Cole, P Svoboda, O Stuchlik, LM Chen, KX Chai, BK Gangrade, OE Sørensen, J Pohl, AM Cole, TB Geijtenbeek |
PloS one | 2011 |
|
Phagosome dynamics during phagocytosis by neutrophils
P Nordenfelt, H Tapper |
Journal of leukocyte biology | 2011 |
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Efficient Screening of a Novel Antimicrobial Peptide from Jatropha curcas by Cell Membrane Affinity Chromatography
J Xiao, H Zhang, L Niu, X Wang |
Journal of Agricultural and Food Chemistry | 2011 |
|
Host-defense peptides: from biology to therapeutic strategies
ML Mangoni |
Cellular and Molecular Life Sciences | 2011 |
|
Neutrophil alpha-defensins cause lung injury by disrupting the capillary-epithelial barrier
K Bdeir, AA Higazi, I Kulikovskaya, M Christofidou-Solomidou, SA Vinogradov, TC Allen, S Idell, R Linzmeier, T Ganz, DB Cines |
American journal of respiratory and critical care medicine | 2010 |
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Inactivation of HIV after transcytosis via adult oral epithelial cells but not fetal epithelial cells
Sharof Tugizov, Rossana Herrera, Piri Veluppillai, Deborah Greenspan, Vanessa Soros, Warner C. Greene, Jay Levy, Joel M. Palefsky |
Virology | 2010 |
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Neuroendocrine Nicotinic Receptor Activation Increases Susceptibility to Bacterial Infections by Suppressing Antimicrobial Peptide Production
KA Radek, PM Elias, L Taupenot, SK Mahata, DT O'Connor, RL Gallo |
Cell Host & Microbe | 2010 |
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Cyclic and acyclic defensins inhibit human immunodeficiency virus type-1 replication by different mechanisms
A Seidel, Y Ye, LR de Armas, M Soto, W Yarosh, RA Marcsisin, D Tran, ME Selsted, D Camerini |
PloS one | 2010 |
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Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression
M Rodríguez-García, N Climent, H Oliva, V Casanova, R Franco, A Leon, JM Gatell, F García, T Gallart |
PloS one | 2010 |
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Antimicrobial Peptides Human β-Defensins and Cathelicidin LL-37 Induce the Secretion of a Pruritogenic Cytokine IL-31 by Human Mast Cells
F Niyonsaba, H Ushio, M Hara, H Yokoi, M Tominaga, K Takamori, N Kajiwara, H Saito, I Nagaoka, H Ogawa, K Okumura |
Journal of immunology (Baltimore, Md. : 1950) | 2010 |
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Differential activity of innate defense antimicrobial peptides against Nocardia species
S Rieg, B Meier, E Fähnrich, A Huth, D Wagner, WV Kern, H Kalbacher |
BMC Microbiology | 2010 |
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Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis
B Riepl, S Grässel, R Wiest, M Fleck, RH Straub |
Arthritis Research & Therapy | 2010 |
|
Topley & Wilson's Microbiology and Microbial Infections
PM Pitha, MS Künzi |
Topley & Wilson's Microbiology and Microbial Infections | 2010 |
|
Neutrophil function after bone marrow and hematopoietic stem cell transplant
C Ramaprasad, S Pouch, DL Pitrak |
Leukemia & Lymphoma | 2010 |
|
Resonance assignment and three-dimensional structure determination of a human alpha-defensin, HNP-1, by solid-state NMR
Y Zhang, T Doherty, J Li, W Lu, C Barinka, J Lubkowski, M Hong |
Journal of Molecular Biology | 2010 |
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Elevated expression of Paneth cell CRS4C in ileitis-prone SAMP1/YitFc mice: regional distribution, subcellular localization, and mechanism of action
MT Shanahan, A Vidrich, Y Shirafuji, CL Dubois, A Henschen-Edman, SJ Hagen, SM Cohn, AJ Ouellette |
The Journal of biological chemistry | 2010 |
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3D (13)C-(13)C-(13)C correlation NMR for de novo distance determination of solid proteins and application to a human alpha-defensin
S Li, Y Zhang, M Hong |
Journal of magnetic resonance (San Diego, Calif. : 1997) | 2010 |
|
MDP-NOD2 stimulation induces HNP-1 secretion, which contributes to NOD2 antibacterial function
JK Yamamoto-Furusho, N Barnich, T Hisamatsu, DK Podolsky |
Inflammatory Bowel Diseases | 2010 |
|
Peptide-based Antifungal Therapies against Emerging Infections
A Matejuk, Q Leng, MD Begum, MC Woodle, P Scaria, ST Chou, AJ Mixson |
Drugs of the future | 2010 |
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Roles of human β-defensins in innate immune defense at the ocular surface: arming and alarming corneal and conjunctival epithelial cells
F Garreis, T Schlorf, D Worlitzsch, P Steven, L Bräuer, K Jäger, FP Paulsen |
Histochemistry and Cell Biology | 2010 |
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Development of adenoviral vector-based mucosal vaccine against influenza
IL Tutykhina, DY Logunov, DN Shcherbinin, MM Shmarov, AI Tukhvatulin, BS Naroditsky, AL Gintsburg |
Journal of Molecular Medicine | 2010 |
|
Defensins in the oral cavity: distribution and biological role
PS Gomes, MH Fernandes |
Journal of Oral Pathology & Medicine | 2010 |
|
Characterization of Kunitz-type protease inhibitor purified from hemolymph of Galleria mellonella larvae
JH Lee, CH Kim, YP Shin, HJ Park, S Park, HM Lee, BS Kim, IH Lee |
Insect Biochemistry and Molecular Biology | 2010 |
|
Antifungal activity of recombinant mouse beta-defensin 3
Y Jiang, Y Wang, B Wang, D Yang, K Yu, X Yang, F Liu, Z Jiang, M Li |
Letters in Applied Microbiology | 2010 |
|
Mechanisms and physiological effects of protamine resistance in Salmonella enterica serovar Typhimurium LT2
M Pranting, DI Andersson |
Journal of Antimicrobial Chemotherapy | 2010 |
|
Role of Two-component System of Streptococcus mutans in the Adaptive Response to the Oral Environment
M Matsuo, H Komatsuzawa |
Journal of Oral Biosciences | 2010 |
|
Expression of human neutrophil proteins in acne vulgaris
E AdıÅen, J Yüksek, O Erdem, FN Aksakal, AB Aksakal |
Journal of the European Academy of Dermatology and Venereology | 2010 |
|
Antimicrobial Peptides from the Marine Fishes
S Ravichandr, K Kumaravel, G Rameshkuma, TT AjithKumar |
Research Journal of Immunology | 2010 |
|
Functional Interaction of Human Neutrophil Peptide-1 with the cell wall precursor Lipid II
E Leeuw, C Li, P Zeng, C Li, MD Buin, WY Lu, E Breukink, W Lu |
FEBS Letters | 2010 |
|
Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases
VG Fowler, WM Scheld, AS Bayer |
Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases | 2010 |
|
Rook's Textbook of Dermatology: Burns/Rook's Textbook of Dermatology
PS Friedmann, MR Ardern-Jones, CA Holden |
Rook's Textbook of Dermatology: Burns/Rook's Textbook of Dermatology | 2010 |
|
Cummings Otolaryngology - Head and Neck Surgery
BW O’Malley, D Li, WM Abuzeid, H Staecker |
Cummings Otolaryngology - Head and Neck Surgery | 2010 |
|
Comprehensive Natural Products II
RL Fagan, BA Palfey |
Comprehensive Natural Products II | 2010 |
|
Trp-26 Imparts Functional Versatility to Human α-Defensin HNP1
G Wei, M Pazgier, E Leeuw, M Rajabi, J Li, G Zou, G Jung, W Yuan, WY Lu, RI Lehrer, W Lu |
The Journal of biological chemistry | 2010 |
|
Insight into the Mechanisms of Adenovirus Capsid Disassembly from Studies of Defensin Neutralization
JG Smith, M Silvestry, S Lindert, W Lu, GR Nemerow, PL Stewart, B Sherry |
PLoS pathogens | 2010 |
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Rhesus macaque θ-defensin isoforms: expression, antimicrobial activities, and demonstration of a prominent role in neutrophil granule microbicidal activities
P Tongaonkar, P Tran, K Roberts, J Schaal, G Ösapay, D Tran, AJ Ouellette, ME Selsted |
Journal of leukocyte biology | 2010 |
|
Review: Defensins and cathelicidins in lung immunity
N Palaniyar, T Tecle, S Tripathi, KL Hartshorn |
Innate immunity | 2010 |
|
Human β-Defensin 2 and β-Defensin 3 Chimeric Peptides Reveal the Structural Basis of the Pathogen Specificity of Their Parent Molecules
S Jung, J Mysliwy, B Spudy, I Lorenzen, K Reiss, C Gelhaus, R Podschun, M Leippe, J Grötzinger |
Antimicrobial agents and chemotherapy | 2010 |
|
Induction of neutrophil degranulation by S100A9 via a MAPK-dependent mechanism
JC Simard, D Girard, PA Tessier |
Journal of leukocyte biology | 2010 |
|
The Future of Aging
GM Fahy, MD West, LS Coles, SB Harris |
2010 | |
|
National Institute of Allergy and Infectious Diseases, NIH
VS Georgiev |
2010 | |
|
Marsupial Genetics and Genomics
JE Deakin, PD Waters, JA Graves |
2010 | |
|
Interaction of Human β-Defensin 2 (HBD2) with Glycosaminoglycans
ES Seo, BS Blaum, T Vargues, MD Cecco, JA Deakin, M Lyon, PE Barran, DJ Campopiano, D Uhrín |
Biochemistry | 2010 |
|
The Membrane-Bound Structure and Topology of a Human α-Defensin Indicate a Dimer Pore Mechanism for Membrane Disruption
Y Zhang, W Lu, M Hong |
Biochemistry | 2010 |
|
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
|
Alarmins link neutrophils and dendritic cells
D Yang, G la Rosa, P Tewary, JJ Oppenheim |
Trends in Immunology | 2009 |
|
Alarmins and antimicrobial immunity
D Yang, JJ Oppenheim |
Medical Mycology | 2009 |
|
Borrelia burgdorferi Resistance to a Major Skin Antimicrobial Peptide Is Independent of Outer Surface Lipoprotein Content
A Sarkar, K Tilly, P Stewart, A Bestor, JM Battisti, PA Rosa |
Antimicrobial agents and chemotherapy | 2009 |
|
Through the looking glass, mechanistic insights from enantiomeric human defensins
G Wei, E Leeuw, M Pazgier, W Yuan, G Zou, J Wang, B Ericksen, WY Lu, RI Lehrer, W Lu |
The Journal of biological chemistry | 2009 |
|
On the Physiology and Pathophysiology of Antimicrobial Peptides
R Pálffy, R Gardlík, M Behuliak, L Kadasi, J Turna, P Celec |
Molecular Medicine | 2009 |
|
Differential expression pattern of genes encoding for anti-microbial peptides in the fetal membranes of patients with spontaneous preterm labor and intact membranes and those with preterm prelabor rupture of the membranes
O Erez, R Romero, AL Tarca, T Chaiworapongsa, YM Kim, NG Than, E Vaisbuch, S Draghici, G Tromp |
Journal of Maternal-Fetal and Neonatal Medicine | 2009 |
|
Alarmins and antimicrobial immunity
D Yang, JJ Oppenheim |
Medical Mycology | 2009 |
|
Impact of α-defensins1–3 on the maturation and differentiation of human monocyte-derived DCs. Concentration-dependent opposite dual effects
M Rodríguez-García, H Oliva, N Climent, MM Escribese, F García, TM Moran, JM Gatell, T Gallart |
Clinical Immunology | 2009 |
|
Study of human neutrophil peptides in saliva by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
MH Yang, LH Lo, YH Chen, J Shiea, PC Wu, YC Tyan, YJ Jong |
Rapid Communications in Mass Spectrometry | 2009 |
|
Protease inhibitors derived from elafin and SLPI and engineered to have enhanced specificity towards neutrophil serine proteases
ML Zani, K Baranger, N Guyot, S Dallet-Choisy, T Moreau |
Protein science : a publication of the Protein Society | 2009 |
|
Differential Processing of {alpha}- and {beta}-Defensin Precursors by Matrix Metalloproteinase-7 (MMP-7)
CL Wilson, AP Schmidt, E Pirilä, EV Valore, N Ferri, T Sorsa, T Ganz, WC Parks |
The Journal of biological chemistry | 2009 |
|
Host defense and pathogenesis in Staphylococcus aureus infections
FR DeLeo, BA Diep, M Otto |
Infectious Disease Clinics of North America | 2009 |
|
Structure, membrane orientation, mechanism, and function of pexiganan--a highly potent antimicrobial peptide designed from magainin
LM Gottler, A Ramamoorthy |
Biochimica et Biophysica Acta | 2009 |
|
Antimicrobial peptide mimics for improved therapeutic properties
S Rotem, A Mor |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 2009 |
|
Multifunctional host defense peptides: Antimicrobial peptides, the small yet big players in innate and adaptive immunity
C Auvynet, Y Rosenstein |
FEBS Journal | 2009 |
|
Inhibitory effect of HMGN2 protein on human hepatitis B virus expression and replication in the HepG2.2.15 cell line
Y Feng, F He, P Zhang, Q Wu, N Huang, H Tang, X Kong, Y Li, J Lu, Q Chen, B Wang |
Antiviral Research | 2009 |
|
A peptide with potent antifungal and antiproliferative activities from Nepalese large red beans
DZ Ma, HX Wang, TB Ng |
Peptides | 2009 |
|
Soluble fusion expression and characterization of bioactive human beta-defensin 26 and 27
L Huang, SS Leong, R Jiang |
Applied Microbiology and Biotechnology | 2009 |
|
A defensin with highly potent antipathogenic activities from the seeds of purple pole bean
P Lin, JH Wong, TB Ng |
Bioscience Reports | 2009 |
|
Selective arginines are important for the antibacterial activity and host cell interaction of human α-defensin 5
E Leeuw, M Rajabi, G Zou, M Pazgier, W Lu |
FEBS Letters | 2009 |
|
Existence of functional lingual antimicrobial peptide in bovine milk
N Isobe, J Nakamura, H Nakano, Y Yoshimura |
Journal of Dairy Science | 2009 |
|
Electropositive Charge in α-Defensin Bactericidal Activity: Functional Effects of Lys-for-Arg Substitutions Vary with the Peptide Primary Structure▿ §
RA Llenado, CS Weeks, MJ Cocco, AJ Ouellette |
Infection and immunity | 2009 |
|
Antimicrobial properties of the equine α-defensin DEFA1 against bacterial horse pathogens
O Bruhn, J Cauchard, M Schlusselhuber, C Gelhaus, R Podschun, G Thaller, C Laugier, M Leippe, J Grötzinger |
Veterinary Immunology and Immunopathology | 2009 |
|
Cationic polypeptides contribute to the anti-HIV-1 activity of human seminal plasma
JA Martellini, AL Cole, N Venkataraman, GA Quinn, P Svoboda, BK Gangrade, J Pohl, OE Sørensen, AM Cole |
The FASEB Journal | 2009 |
|
Bioactive Peptides
J Rehfeld |
Bioactive Peptides | 2009 |
|
Atopic Dermatitis, Second Edition
E Proksch, R Fölster-Holst, JM Jensen |
Atopic Dermatitis, Second Edition | 2009 |
|
Preparation of isotopically labelled recombinant β-defensin for NMR studies
ES Seo, T Vargues, DJ Clarke, D Uhrín, DJ Campopiano |
Protein Expression and Purification | 2009 |
|
Differential Processing of α- and β-Defensin Precursors by Matrix Metalloproteinase-7 (MMP-7)
CL Wilson, AP Schmidt, E Pirilä, EV Valore, N Ferri, T Sorsa, T Ganz, WC Parks |
The Journal of biological chemistry | 2009 |
|
α-Defensins in Enteric Innate Immunity: FUNCTIONAL PANETH CELL α-DEFENSINS IN MOUSE COLONIC LUMEN
JR Mastroianni, AJ Ouellette |
The Journal of biological chemistry | 2009 |
|
NOD2/CARD15 on bone marrow CD34+ hematopoietic cells mediates induction of cytokines and cell differentiation
M Sioud, Y Fløisand |
Journal of leukocyte biology | 2009 |
|
Human defensins activate monocyte-derived dendritic cells, promote the production of proinflammatory cytokines, and up-regulate the surface expression of CD91
P Presicce, S Giannelli, A Taddeo, ML Villa, SD Bella |
Journal of leukocyte biology | 2009 |
|
Human α-Defensins Inhibit Hemolysis Mediated by Cholesterol-Dependent Cytolysins
RI Lehrer, G Jung, P Ruchala, W Wang, ED Micewicz, AJ Waring, EJ Gillespie, KA Bradley, AJ Ratner, RF Rest, W Lu |
Infection and immunity | 2009 |
|
Multivalent Binding of Carbohydrates by the Human α-Defensin, HD5
RI Lehrer, G Jung, P Ruchala, S Andre, HJ Gabius, W Lu |
Journal of immunology (Baltimore, Md. : 1950) | 2009 |
|
Neutrophil-derived HBP and HNP1-3 boost bacterial phagocytosis by macrophage
Oliver Soehnlein, Ylva Kai-Larsen, Robert Frithiof, Ole E. Sorensen, Ellinor Kenne, Karin Scharffetter-Kochanek, Einar E. Eriksson, Heiko Herwald, Birgitta Agerberth, Lennart Lindbom |
Journal of Clinical Investigation | 2008 |
|
Host defense peptides in wound healing
L Steinstraesser, T Koehler, F Jacobsen, A Daigeler, O Goertz, S Langer, M Kesting, H Steinau, E Eriksson, T Hirsch |
Molecular Medicine | 2008 |
|
Salivary mucins inhibit antibacterial activity of the cathelicidin-derived LL-37 peptide but not the cationic steroid CSA-13
R Bucki, DB Namiot, Z Namiot, PB Savage, PA Janmey |
The Journal of antimicrobial chemotherapy | 2008 |
|
The role of antimicrobial peptides at the ocular surface
AM McDermott |
Ophthalmic Research | 2008 |
|
Molecular regulation of inflammation and cell death
G Yeretssian, K Labbé, M Saleh |
Cytokine | 2008 |
|
Antimicrobial peptides, skin infections, and atopic dermatitis
TR Hata, RL Gallo |
Seminars in Cutaneous Medicine and Surgery | 2008 |
|
Novartis Foundation Symposia
EJ Campbell |
Ciba Foundation Symposium 44 - Research and Medical Practice: Their Interaction | 2008 |
|
The phagocytes: neutrophils and monocytes
DC Dale, L Boxer, WC Liles |
Blood | 2008 |
|
rVSV(MΔ51)-M3 Is an Effective and Safe Oncolytic Virus for Cancer Therapy
L Wu, T Huang, M Meseck, J Altomonte, O Ebert, K Shinozaki, A García-Sastre, J Fallon, J Mandeli, SL Woo |
Human Gene Therapy | 2008 |
|
Studies on anticancer activities of antimicrobial peptides
DW Hoskin, A Ramamoorthy |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 2008 |
|
Urinary protein profiling with surface-enhanced laser desorption/ionization time-of-flight mass spectrometry in ETBreceptor-deficient ratsThis article is one of a selection of papers published in the special issue (part 2 of 2) on Forefronts in Endothelin
J Raila, P Kalk, T Pfab, C Thöne-Reineke, M Godes, M Yanagisawa, FJ Schweigert, B Hocher |
Canadian Journal of Physiology and Pharmacology | 2008 |
|
A role for antimicrobial peptides in intestinal microsporidiosis
GJ Leitch, C Ceballos |
Parasitology | 2008 |
|
Molecular determinants for the interaction of human neutrophil alpha defensin 1 with its propeptide
G Zou, E Leeuw, J Lubkowski, W Lu |
Journal of Molecular Biology | 2008 |
|
Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides
NP Chongsiriwatana, JA Patch, AM Czyzewski, MT Dohm, A Ivankin, D Gidalevitz, RN Zuckermann, AE Barron |
Proceedings of the National Academy of Sciences | 2008 |
|
Microbicidal protein psoriasin is a multifunctional modulator of neutrophil activation
Y Zheng, F Niyonsaba, H Ushio, S Ikeda, I Nagaoka, K Okumura, H Ogawa |
Immunology | 2008 |
|
Toll-like receptors in skin infections and inflammatory diseases
Y Lai, RL Gallo |
Infectious disorders drug targets | 2008 |
|
In vitro susceptibility of the Streptococcus milleri group to antimicrobial peptides
KL Bartie, DA Devine, MJ Wilson, MA Lewis |
International Endodontic Journal | 2008 |
|
In vivo modulation of the rainbow trout (Oncorhynchus mykiss) immune response by the human alpha defensin 1, HNP1
A Falco, I Brocal, L Pérez, JM Coll, A Estepa, C Tafalla |
Fish & Shellfish Immunology | 2008 |
|
Mechanism of Adenovirus Neutralization by Human α-Defensins
JG Smith, GR Nemerow |
Cell Host & Microbe | 2008 |
|
Production and purification of a cecropin family antibacterial peptide, hinnavin II, in Escherichia coli
CS Kang, CW Park, IS Bang |
Biotechnology and Bioprocess Engineering | 2008 |
|
Role of antimicrobial peptides in host defense against mycobacterial infections
P Méndez-Samperio |
Peptides | 2008 |
|
Functional domains of the human epididymal protease inhibitor, eppin
MT McCrudden, TR Dafforn, DF Houston, PT Turkington, DJ Timson |
FEBS Journal | 2008 |
|
Using antimicrobial host defense peptides as anti-infective and immunomodulatory agents
T Kruse, HH Kristensen |
Expert Review of Anti-infective Therapy | 2008 |
|
Transcriptional Profile of Escherichia coli in Response to Novispirin G10
T Kruse, B Christensen, D Raventós, AK Nielsen, JD Nielsen, N Vukmirovic, HH Kristensen |
International Journal of Peptide Research and Therapeutics | 2008 |
|
Az antimikrobiális (gazdavédő) kis peptidek élettani és kórtani jelentősége
K Lapis |
Orvosi Hetilap | 2008 |
|
An antifungal protein fromBacillus amyloliquefaciens
JH Wong, J Hao, Z Cao, M Qiao, H Xu, Y Bai, TB Ng |
Journal of Applied Microbiology | 2008 |
|
Expression of human β-defensin -1, -2, and -3 in non-inflamed pseudocyst, mucoceles
MK Frederic, T Yamaai, N Mizukawa, Y Kaneda, N Katase, M Gunduz, H Nagatsuka, T Sugahara |
Oral Diseases | 2008 |
|
Human neutrophil peptides 1-3 are useful biomarkers in patients with active ulcerative colitis
S Kanmura, H Uto, M Numata, S Hashimoto, A Moriuchi, H Fujita, M Oketani, A Ido, M Kodama, H Ohi, H Tsubouchi |
Inflammatory Bowel Diseases | 2008 |
|
Handbook of New Technologies for Genetic Improvement of Legumes
T Ng, J Wong |
Handbook of New Technologies for Genetic Improvement of Legumes | 2008 |
|
Host Defense Systems of the Lung
JB Kang, GL Larsen |
Pediatric Respiratory Medicine | 2008 |
|
Avian defensins
A Dijk, EJ Veldhuizen, HP Haagsman |
Veterinary Immunology and Immunopathology | 2008 |
|
Studies in Natural Products Chemistry
M Seki |
Studies in Natural Products Chemistry | 2008 |
|
Urinary protein profiling with surface-enhanced laser desorption/ionization time-of-flight mass spectrometry in ET B receptor-deficient ratsThis article is one of a selection of papers published in the special issue (part 2 of 2) on Forefronts in Endothelin
J Raila, P Kalk, T Pfab, C Thöne-Reineke, M Godes, M Yanagisawa, FJ Schweigert, B Hocher |
Canadian Journal of Physiology and Pharmacology | 2008 |
|
Clinical Biochemistry of Domestic Animals
BC Tennant, SA Center |
Clinical Biochemistry of Domestic Animals | 2008 |
|
Textbook of Pleural Diseases Second Edition
S Shetty, J John, S Idell |
Textbook of Pleural Diseases Second Edition: pleural disease other than mesothelioma | 2008 |
|
Beta defensin 2 gene copy variations influence mRNA expression and protein release in whole blood cultures from healthy individuals: 12AP1-1
M Book, Q Chen, X Zhang, A Hoeft, F Stuber |
European Journal of Anaesthesiology | 2008 |
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Ocular Therapeutics
MY Kahook, JS Schuman |
Ocular Therapeutics | 2008 |
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The Conserved Salt Bridge in Human α-Defensin 5 Is Required for Its Precursor Processing and Proteolytic Stability
M Rajabi, E Leeuw, M Pazgier, J Li, J Lubkowski, W Lu |
The Journal of biological chemistry | 2008 |
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In Vitro Activation of the Rhesus Macaque Myeloid α-Defensin Precursor proRMAD-4 by Neutrophil Serine Proteinases
K Kamdar, A Maemoto, X Qu, SK Young, AJ Ouellette |
The Journal of biological chemistry | 2008 |
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Pathophysiology of the Pleura
MA Jantz, VB Antony |
Respiration | 2008 |
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Neutrophils Play an Essential Role in Cooperation with Antibody in both Protection against and Recovery from Pulmonary Infection with Influenza Virus in Mice
H Fujisawa |
Journal of virology | 2008 |
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Comprehensive Defensin Assay for Saliva
MS Gardner, MD Rowland, AY Siu, JL Bundy, DK Wagener, JL Stephenson |
Analytical Chemistry | 2008 |
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Avian defensins
A van Dijk, EJ Veldhuizen, HP Haagsman |
Veterinary Immunology and Immunopathology | 2008 |
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Alpha-defensins block the early steps of HIV-1 infection: interference with the binding of gp120 to CD4
L Furci, F Sironi, M Tolazzi, L Vassena, P Lusso |
Blood | 2007 |
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Human Defensin α-1 Causes Trypanosoma cruzi Membrane Pore Formation and Induces DNA Fragmentation, Which Leads to Trypanosome Destruction
MN Madison, YY Kleshchenko, PN Nde, KJ Simmons, MF Lima, F Villalta |
Infection and immunity | 2007 |
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Antimicrobial peptides: natural effectors of the innate immune system
K Radek, R Gallo |
Seminars in Immunopathology | 2007 |
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Antimicrobial peptides in human skin disease
K Yamasaki, RL Gallo |
European journal of dermatology : EJD | 2007 |
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Host factors influencing susceptibility to HIV infection and AIDS progression
J Lama, V Planelles |
Retrovirology | 2007 |
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Leukotriene B 4 Triggers the In Vitro and In Vivo Release of Potent Antimicrobial Agents
L Flamand, MJ Tremblay, P Borgeat |
Journal of immunology (Baltimore, Md. : 1950) | 2007 |
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Effects of surfactant protein D on growth, adhesion and epithelial invasion of intestinal Gram-negative bacteria
A Hogenkamp, MV Herías, PC Tooten, EJ Veldhuizen, HP Haagsman |
Molecular Immunology | 2007 |
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Impact of pro segments on the folding and function of human neutrophil alpha-defensins
Z Wu, X Li, B Ericksen, E Leeuw, G Zou, P Zeng, C Xie, C Li, J Lubkowski, WY Lu, W Lu |
Journal of Molecular Biology | 2007 |
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Inhibition of human neutrophil degranulation by transforming growth factor-beta1
L Shen, JM Smith, Z Shen, M Eriksson, C Sentman, CR Wira |
Clinical & Experimental Immunology | 2007 |
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Protective immunity against cryptococcus neoformans infection
J Schop |
McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students | 2007 |
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The expression of human alpha and beta defensin in the endometrium and their effect on implantation
S Das, GS Vince, I Lewis-Jones, MD Bates, R Gazvani |
Journal of Assisted Reproduction and Genetics | 2007 |
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Intein-mediated expression is an effective approach in the study of β-defensins
H Diao, C Guo, D Lin, Y Zhang |
Biochemical and Biophysical Research Communications | 2007 |
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Immunocytochemical localization of lysozyme and β-defensin in the apocrine glands of the equine scrotum
T Yasui, K Fukui, T Nara, I Habata, W Meyer, A Tsukise |
Archives of Dermatological Research | 2007 |
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Innate Immune Defences in the Human Uterus during Pregnancy
AE King, RW Kelly, JM Sallenave, AD Bocking, JR Challis |
Placenta | 2007 |
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The role of human innate immune factors in nasal colonization by Staphylococcus aureus
A Belkum, M Emonts, H Wertheim, C Jongh, J Nouwen, H Bartels, A Cole, A Cole, P Hermans, H Boelens, NL Toom, S Snijders, H Verbrugh, W Leeuwen |
Microbes and Infection | 2007 |
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Defensins in the immunology of bacterial infections
A Menendez, BB Finlay |
Current Opinion in Immunology | 2007 |
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The role of cathelicidin and defensins in pulmonary inflammatory diseases
C Herr, R Shaykhiev, R Bals |
Expert Opinion on Biological Therapy | 2007 |
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Analysis of differential gene expression between chronic hepatitis B patients and asymptomatic hepatitis B carriers
C Tang, Z Chen, G Peng, Z Yang, L Zhou |
Journal of Gastroenterology and Hepatology | 2007 |
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Effects of Acute Ethanol Exposure on the Early Inflammatory Response After Excisional Injury
DJ Fitzgerald, KA Radek, M Chaar, DE Faunce, LA DiPietro, EJ Kovacs |
Alcoholism, clinical and experimental research | 2007 |
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Genetics of the innate immune response in inflammatory bowel disease
JV Limbergen, RK Russell, ER Nimmo, GT Ho, ID Arnott, DC Wilson, J Satsangi |
Inflammatory Bowel Diseases | 2007 |
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The polymorphism in the ?4-defensin gene and its association with production and somatic cell count in Holstein-Friesian cows
E Bagnicka, N Strzałkowska, K Flisikowski, T Szreder, A Jóźwik, B Prusak, J Krzyżewski, L Zwierzchowski |
Journal of Animal Breeding and Genetics | 2007 |
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Phagocytosis and antigen presentation in dendritic cells
A Savina, S Amigorena |
Immunological Reviews | 2007 |
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Cathelicidin LL-37 induces the generation of reactive oxygen species and release of human α-defensins from neutrophils
Y Zheng, F Niyonsaba, H Ushio, I Nagaoka, S Ikeda, K Okumura, H Ogawa |
British Journal of Dermatology | 2007 |
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Dual antiviral activity of human alpha-defensin-1 against viral haemorrhagic septicaemia rhabdovirus (VHSV): Inactivation of virus particles and induction of a type I interferon-related response
A Falco, V Mas, C Tafalla, L Perez, JM Coll, A Estepa |
Antiviral Research | 2007 |
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Discovery of α-defensins in basal mammals
DJ Lynn, DG Bradley |
Developmental & Comparative Immunology | 2007 |
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REVIEW ARTICLE: Antimicrobial Polypeptides are Key Anti-HIV-1 Effector Molecules of Cervicovaginal Host Defense
AM Cole, AL Cole |
American Journal of Reproductive Immunology | 2007 |
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Molecular cloning and characterization of lysozyme II fromArtogeia rapaeand its expression in Baculovirus‐infected insect cells
IS Bang, CS Kang |
Integrative Biosciences | 2007 |
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Efficient production of soluble human beta-defensin-3–4 fusion proteins in Escherichia coli cell-free system
H Chen, L Fan, Z Xu, X Yin, P Cen |
Process Biochemistry | 2007 |
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Human β-defensin-2: A natural antimicrobial peptide present in amniotic fluid participates in the host response to microbial invasion of the amniotic cavity
E Soto, J Espinoza, JK Nien, JP Kusanovic, O Erez, K Richani, J Santolaya-Forgas, RR Chief |
Journal of Maternal-Fetal and Neonatal Medicine | 2007 |
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Review: Human antimicrobial proteins — effectors of innate immunity
J Harder, R Gläser, JM Schröder |
Journal of Endotoxin Research | 2007 |
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Human immature monocyte-derived dendritic cells produce and secrete α-defensins 1-3
M Rodríguez-García, H Oliva, N Climent, F García, JM Gatell, T Gallart |
Journal of leukocyte biology | 2007 |
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Differential Expression of Human Beta Defensin 2 and Human Beta Defensin 3 in Human Middle Ear Cholesteatoma
JJ Song, SW Chae, JS Woo, HM Lee, HH Jung, SJ Hwang |
The Annals of otology, rhinology, and laryngology | 2007 |
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Toward Understanding the Cationicity of Defensins: ARG AND LYS VERSUS THEIR NONCODED ANALOGS
G Zou, E Leeuw, C Li, M Pazgier, C Li, P Zeng, WY Lu, J Lubkowski, W Lu |
The Journal of biological chemistry | 2007 |
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Mechanisms of action of ostrich β-defensins against Escherichia coli
H Sugiarto, PL Yu |
FEMS Microbiology Letters | 2007 |
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New Insights in Medical Mycology
K Kavanagh |
2007 | |
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The β-Defensin Gallinacin-6 Is Expressed in the Chicken Digestive Tract and Has Antimicrobial Activity against Food-Borne Pathogens
A van Dijk, EJ Veldhuizen, SI Kalkhove, JL Bokhoven, RA Romijn, HP Haagsman |
Antimicrobial agents and chemotherapy | 2007 |
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Study of the Interaction of Human Defensins with Cell Membrane Models: Relationships between Structure and Biological Activity
MR Lourenzoni, AM Namba, L Caseli, L Degrève, ME Zaniquelli |
The Journal of Physical Chemistry B | 2007 |
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In Vitro Activity of Human β-Defensin 2 against Pseudomonas aeruginosa in the Presence of Tear Fluid
LC Huang, RL Redfern, S Narayanan, RY Reins, AM McDermott |
Antimicrobial agents and chemotherapy | 2007 |
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A novel horse α-defensin: gene transcription, recombinant expression and characterization of the structure and function
O Bruhn, P Regenhard, M Michalek, S Paul, C Gelhaus, S Jung, G Thaller, R Podschun, M Leippe, J Grötzinger, E Kalm |
Biochemical Journal | 2007 |
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The Expression Patterns of Peritoneal Defensins
A Grupp, M Kimmel, P Fritz, B Voggenreiter, H Stöltzing, U Kuhlmann, EF Stange, T Mettang, K Fellermann, DM Alscher |
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis | 2007 |
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Alpha-defensin increase in peripheral blood mononuclear cells from patients with hepatitis C virus chronic infection
A Aceti, ML Mangoni, C Pasquazzi, D Fiocco, M Marangi, R Miele, B Zechini, M Borro, I Versace, M Simmaco |
Journal of Viral Hepatitis | 2006 |
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Antimicrobial Peptides and Human Disease
WM Shafer |
2006 | |
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The changing of the guard: Molecular diversity and rapid evolution of β-defensins
CA Semple, P Gautier, K Taylor, JR Dorin |
Molecular Diversity | 2006 |
|
CC Chemokines Induce Neutrophils to Chemotaxis, Degranulation, and ??-Defensin Release
MS Jan, YH Huang, B Shieh, RH Teng, YP Yan, YT Lee, KK Liao, C Li |
JAIDS Journal of Acquired Immune Deficiency Syndromes | 2006 |
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Defensins in innate antiviral immunity
ME Klotman, TL Chang |
Nature Reviews Immunology | 2006 |
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Crystal structures of human alpha-defensins HNP4, HD5, and HD6
A Szyk, Z Wu, K Tucker, D Yang, W Lu, J Lubkowski |
Protein science : a publication of the Protein Society | 2006 |
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Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: an association study
AM Wallace, JQ He, KM Burkett, J Ruan, JE Connett, NR Anthonisen, PD Paré, AJ Sandford |
Respiratory Research | 2006 |
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The front line of enteric host defense against unwelcome intrusion of harmful microorganisms: mucins, antimicrobial peptides, and microbiota
VL Moal, AL Servin |
Clinical microbiology reviews | 2006 |
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Expression of β Defensins in Ocular Surface Tissue of Experimentally Developed Allergic Conjunctivitis Mouse Model
A Ikeda, Y Nakanishi, T Sakimoto, J Shoji, M Sawa, N Nemoto |
Japanese Journal of Ophthalmology | 2006 |
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Aurelin, a novel antimicrobial peptide from jellyfish Aurelia aurita with structural features of defensins and channel-blocking toxins
TV Ovchinnikova, SV Balandin, GM Aleshina, AA Tagaev, YF Leonova, ED Krasnodembsky, AV Men’shenin, VN Kokryakov |
Biochemical and Biophysical Research Communications | 2006 |
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Antimicrobial Activity of Inducible Human β Defensin-2 Against Mycoplasma pneumoniae
K Kuwano, N Tanaka, T Shimizu, Y Kida |
Current Microbiology | 2006 |
|
A mitogenic defensin from white cloud beans (Phaseolus vulgaris)
JH Wong, XQ Zhang, HX Wang, TB Ng |
Peptides | 2006 |
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Recent advances in the research and development of human defensins
H Chen, Z Xu, L Peng, X Fang, X Yin, N Xu, P Cen |
Peptides | 2006 |
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Expression Pattern of Human Neutrophil Peptides (HNP 1-3) in Chronic Hyperplastic Candidiasis
AA Sewvandini, I Morio, M Sunakawa, K Nagumo, N Okada |
Oral Medicine & Pathology | 2006 |
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The MprF protein is required for lysinylation of phospholipids in listerial membranes and confers resistance to cationic antimicrobial peptides (CAMPs) on Listeria monocytogenes
K Thedieck, T Hain, W Mohamed, BJ Tindall, M Nimtz, T Chakraborty, J Wehland, L Jänsch |
Molecular Microbiology | 2006 |
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Advances in antimicrobial peptide immunobiology
NY Yount, AS Bayer, YQ Xiong, MR Yeaman |
Biopolymers | 2006 |
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Defensin: a multifunctional molecule lives up to its versatile name
C Kim, SH Kaufmann |
Trends in Microbiology | 2006 |
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Expression and purification of Artogeia rapae lysozyme II cDNA in a baculovirus/insect cell system
IS BANG, SM YOE, CS KANG |
Entomological Research | 2006 |
|
Associations between Defensin Polymorphism and Somatic Cell Count in Milk and Milk Utility Traits in Jersey Dairy Cows
K Wojdak-Maksymiec, M Kmieć, A ŻUkiewicz |
Journal of Veterinary Medicine Series A | 2006 |
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Defensins as anti-infective and immunomodulatory agents
K Adermann |
Expert Opinion on Therapeutic Patents | 2006 |
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A flow cytometric assay to monitor antimicrobial activity of defensins and cationic tissue extracts
S Nuding, K Fellermann, J Wehkamp, HA Mueller, EF Stange |
Journal of Microbiological Methods | 2006 |
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Paneth cell antimicrobial peptides: Topographical distribution and quantification in human gastrointestinal tissues
J Wehkamp, H Chu, B Shen, RW Feathers, RJ Kays, SK Lee, CL Bevins |
FEBS Letters | 2006 |
|
Antifungal activity of synthetic peptide derived from halocidin, antimicrobial peptide from the tunicate, Halocynthia aurantium
WS Jang, HK Kim, KY Lee, SA Kim, YS Han, IH Lee |
FEBS Letters | 2006 |
|
Expression and purification of recombinant human α-defensins in Escherichia coli
M Pazgier, J Lubkowski |
Protein Expression and Purification | 2006 |
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Structural and Functional Characterization of the Conserved Salt Bridge in Mammalian Paneth Cell α-Defensins: SOLUTION STRUCTURES OF MOUSE CRYPTDIN-4 AND (E15D)-CRYPTDIN-4
KJ Rosengren, NL Daly, LM Fornander, LM Jönsson, Y Shirafuji, X Qu, HJ Vogel, AJ Ouellette, DJ Craik |
The Journal of biological chemistry | 2006 |
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Oral Antimicrobial Peptides and Biological Control of Caries
BA Dale, R Tao, JR Kimball, RJ Jurevic |
BMC oral health | 2006 |
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Macrophages Acquire Neutrophil Granules for Antimicrobial Activity against Intracellular Pathogens
BH Tan, C Meinken, M Bastian, H Bruns, A Legaspi, MT Ochoa, SR Krutzik, BR Bloom, T Ganz, RL Modlin, S Stenger |
Journal of immunology (Baltimore, Md. : 1950) | 2006 |
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Immune Response and Immunotherapy to Cryptococcus Infections
Q Zhou, WJ Murphy |
Immunologic Research | 2006 |
|
Antimicrobial activity of inducible human beta defensin-2 against Mycoplasma pneumoniae.
Kuwano K, Tanaka N, Shimizu T, Kida Y |
Current Microbiology | 2006 |
|
Peptides Selected for Binding to a Virulent Strain of Haemophilus influenzae by Phage Display Are Bactericidal
SL Bishop-Hurley, FJ Schmidt, AL Erwin, AL Smith |
Antimicrobial agents and chemotherapy | 2005 |
|
Inhibition of pathologic retinal neovascularization by alpha-defensins
M Economopoulou, K Bdeir, DB Cines, F Fogt, Y Bdeir, J Lubkowski, W Lu, KT Preissner, HP Hammes, T Chavakis |
Blood | 2005 |
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Expression and regulation of antimicrobial peptides in articular joints
D Varoga, T Pufe, R Mentlein, S Kohrs, S Grohmann, B Tillmann, J Hassenpflug, F Paulsen |
Annals of Anatomy - Anatomischer Anzeiger | 2005 |
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New mechanisms of skin innate immunity: ASK1-mediated keratinocyte differentiation regulates the expression of beta-defensins, LL37, and TLR2
K Sayama, H Komatsuzawa, K Yamasaki, Y Shirakata, Y Hanakawa, K Ouhara, S Tokumaru, X Dai, M Tohyama, PT Dijke, M Sugai, H Ichijo, K Hashimoto |
European Journal of Immunology | 2005 |
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Human β-Defensins Suppress Human Immunodeficiency Virus Infection: Potential Role in Mucosal Protection
L Sun, CM Finnegan, T Kish-Catalone, R Blumenthal, P Garzino-Demo, GM Maggiore, S Berrone, C Kleinman, Z Wu, S Abdelwahab, W Lu, A Garzino-Demo |
Journal of virology | 2005 |
|
Cationic Polypeptides Are Required for Anti-HIV-1 Activity of Human Vaginal Fluid
N Venkataraman, AL Cole, P Svoboda, J Pohl, AM Cole |
Journal of immunology (Baltimore, Md. : 1950) | 2005 |
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Innate defences against methicillin-resistantStaphylococcus aureus (MRSA) infection
H Komatsuzawa, K Ouhara, S Yamada, T Fujiwara, K Sayama, K Hashimoto, M Sugai |
The Journal of Pathology | 2005 |
|
Evolution of caprine and ovine β-defensin genes
K Luenser, J Fickel, A Ludwig |
Immunogenetics | 2005 |
|
Identification and functional analysis ofSalmonella entericaserovar Typhimurium PmrA-regulated genes
R Tamayo, AM Prouty, JS Gunn |
FEMS Immunology & Medical Microbiology | 2005 |
|
Paneth cell α-defensins: peptide mediators of innate immunity in the small intestine
AJ Ouellette |
Springer Seminars in Immunopathology | 2005 |
|
Roles of Group IIA Phospholipase A2 and Complement in Killing of Bacteria by Acute Phase Serum
JO Gronroos, JH Salonen, M Viander, TJ Nevalainen, VJ Laine |
Scandinavian Journal of Immunology | 2005 |
|
Salivary antimicrobial peptide expression and dental caries experience in children
R Tao, RJ Jurevic, KK Coulton, MT Tsutsui, MC Roberts, JR Kimball, N Wells, J Berndt, BA Dale |
Antimicrobial agents and chemotherapy | 2005 |
|
Proline conformation-dependent antimicrobial activity of a proline-rich histone h1 N-terminal Peptide fragment isolated from the skin mucus of Atlantic salmon
T Lüders, GA Birkemo, J Nissen-Meyer, Ø Andersen, IF Nes |
Antimicrobial agents and chemotherapy | 2005 |
|
Human alpha-defensins neutralize anthrax lethal toxin and protect against its fatal consequences
C Kim, N Gajendran, HW Mittrücker, M Weiwad, YH Song, R Hurwitz, M Wilmanns, G Fischer, SH Kaufmann |
Proceedings of the National Academy of Sciences | 2005 |
|
Human defensins
JJ Schneider, A Unholzer, M Schaller, M Schäfer-Korting, HC Korting |
Journal of Molecular Medicine | 2005 |
|
alpha-Helical domain is essential for antimicrobial activity of high mobility group nucleosomal binding domain 2 (HMGN2)1
Y FENG, N HUANG, Q WU, L BAO, B WANG |
Acta Pharmacologica Sinica | 2005 |
|
Effect of Chain Length of Cationic Model Peptides on Antibacterial Activity
T Niidome, N Matsuyama, M Kunihara, T Hatakeyama, H Aoyagi |
Bulletin of the Chemical Society of Japan | 2005 |
|
Antimicrobial peptides: New candidates in the fight against bacterial infections
O Toke |
Biopolymers | 2005 |
|
Susceptibility to infection in patients with neutropenia: the role of the innate immune system
OW Neth, M Bajaj-Elliott, MW Turner, NJ Klein |
British Journal of Haematology | 2005 |
|
Comprehensive sequence analysis of horseshoe crab cuticular proteins and their involvement in transglutaminase-dependent cross-linking
M Iijima, T Hashimoto, Y Matsuda, T Nagai, Y Yamano, T Ichi, T Osaki, S Kawabata |
FEBS Journal | 2005 |
|
Kenojeinin I, antimicrobial peptide isolated from the skin of the fermented skate, Raja kenojei
SH Cho, BD Lee, H An, JB Eun |
Peptides | 2005 |
|
Effects of two hemolymph proteins on humoral defense reactions in the wax moth, Galleria mellonella
SY Park, CH Kim, WH Jeong, JH Lee, SJ Seo, YS Han, IH Lee |
Developmental & Comparative Immunology | 2005 |
|
Innate immune defence in the human gastrointestinal tract
R Dommett, M Zilbauer, JT George, M Bajaj-Elliott |
Molecular Immunology | 2005 |
|
Antimicrobial peptides
A Izadpanah, RL Gallo |
Journal of the American Academy of Dermatology | 2005 |
|
Mucosal Immunology
WR Brown |
Mucosal Immunology | 2005 |
|
Human neutrophil α-defensin 4 inhibits HIV-1 infection in vitro
Z Wu, F Cocchi, D Gentles, B Ericksen, J Lubkowski, A DeVico, RI Lehrer, W Lu |
FEBS Letters | 2005 |
|
Antibacterial activity and specificity of the six human {alpha}-defensins
B Ericksen, Z Wu, W Lu, RI Lehrer |
Antimicrobial agents and chemotherapy | 2005 |
|
Les mécanismes de résistance à la transmission sexuelle du VIH-1
A Eberhard, B Ponceau, F Biron, B Verrier |
Médecine et Maladies Infectieuses | 2005 |
|
Oral Diagnostics for the Geriatric Populations: Current Status and Future Prospects
YA Slaughter, D Malamud |
Dental clinics of North America | 2005 |
|
Susceptibilities of periodontopathogenic and cariogenic bacteria to antibacterial peptides, β-defensins and LL37, produced by human epithelial cells
K Ouhara, H Komatsuzawa, S Yamada, H Shiba, T Fujiwara, M Ohara, K Sayama, K Hashimoto, H Kurihara, M Sugai |
Journal of Antimicrobial Chemotherapy | 2005 |
|
Prodefensins are matrix proteins of specific granules in human neutrophils
M Faurschou, S Kamp, JB Cowland, L Udby, AH Johnsen, J Calafat, H Winther, N Borregaard |
Journal of leukocyte biology | 2005 |
|
HMGN2: a novel antimicrobial effector molecule of human mononuclear leukocytes?
Y Feng, N Huang, Q Wu, B Wang |
Journal of leukocyte biology | 2005 |
|
Why Is the Arg 5 -Glu 13 Salt Bridge Conserved in Mammalian α-Defensins?
Z Wu, X Li, E Leeuw, B Ericksen, W Lu |
The Journal of biological chemistry | 2005 |
|
Targeting Breast and Prostate Cancers Through Their Hormone Receptors1
C Leuschner, W Hansel |
Biology of reproduction | 2005 |
|
Leukotriene B 4 Protects Latently Infected Mice against Murine Cytomegalovirus Reactivation following Allogeneic Transplantation
J Gosselin, P Borgeat, L Flamand |
Journal of immunology (Baltimore, Md. : 1950) | 2005 |
|
Pathogenicity of Influenza Viruses with Genes from the 1918 Pandemic Virus: Functional Roles of Alveolar Macrophages and Neutrophils in Limiting Virus Replication and Mortality in Mice
TM Tumpey, A García-Sastre, JK Taubenberger, P Palese, DE Swayne, MJ Pantin-Jackwood, S Schultz-Cherry, A Solórzano, NV Rooijen, JM Katz, CF Basler |
Journal of virology | 2005 |
|
Colonization of Mucosal Surfaces
JP Nataro, PS Cohen, HL Mobley, JN Weiser |
2005 | |
|
Induction of Keratinocyte Migration via Transactivation of the Epidermal Growth Factor Receptor by the Antimicrobial Peptide LL-37
S Tokumaru, K Sayama, Y Shirakata, H Komatsuzawa, K Ouhara, Y Hanakawa, Y Yahata, X Dai, M Tohyama, H Nagai, L Yang, S Higashiyama, A Yoshimura, M Sugai, K Hashimoto |
Journal of immunology (Baltimore, Md. : 1950) | 2005 |
|
Regulation of neovascularization by human neutrophil peptides (alpha-defensins): a link between inflammation and angiogenesis
T Chavakis, DB Cines, JS Rhee, OD Liang, U Schubert, HP Hammes, AA Higazi, PP Nawroth, KT Preissner, K Bdeir |
The FASEB Journal | 2004 |
|
High bactericidal efficiency of type iia phospholipase A2 against Bacillus anthracis and inhibition of its secretion by the lethal toxin
AP Gimenez, YZ Wu, M Paya, C Delclaux, L Touqui, PL Goossens |
Journal of immunology (Baltimore, Md. : 1950) | 2004 |
|
Primate defensins
RI Lehrer |
Nature Reviews Microbiology | 2004 |
|
Multiple Roles of Antimicrobial Defensins, Cathelicidins, and Eosinophil-Derived Neurotoxin in Host Defense*
D Yang, A Biragyn, DM Hoover, J Lubkowski, JJ Oppenheim |
Annual Review of Immunology | 2004 |
|
Human α Defensin in HIV-Exposed But Uninfected Individuals
D Trabattoni, SL Caputo, G Maffeis, F Vichi, M Biasin, P Pierotti, F Fasano, M Saresella, M Franchini, P Ferrante, F Mazzotta, M Clerici |
JAIDS Journal of Acquired Immune Deficiency Syndromes | 2004 |
|
Defensins and other antimicrobial peptides at the ocular surface
AM McDermott |
The ocular surface | 2004 |
|
Exploiting the potential of insects for in vivo pathogenicity testing of microbial pathogens
K Kavanagh, EP Reeves |
FEMS Microbiology Reviews | 2004 |
|
Purification of antimicrobial factor from granules of channel catfish peripheral blood leucocytes
DD Ourth, KT Chung |
Biochemical and Biophysical Research Communications | 2004 |
|
Antimicrobial peptides and the skin
A Bardan, V Nizet, RL Gallo |
Expert Opinion on Biological Therapy | 2004 |
|
Gingival defensins: linking the innate and adaptive immune responses to dental plaque
RI Marshall |
Periodontology 2000 | 2004 |
|
Insights into the anti-microbial defense of marine invertebrates: the penaeid shrimps and the oyster Crassostrea gigas
E Bachere, Y Gueguen, M Gonzalez, J Lorgeril, J Garnier, B Romestand |
Immunological Reviews | 2004 |
|
The Paneth cell and the innate immune response
CL Bevins |
Current Opinion in Gastroenterology | 2004 |
|
Penicillin-induced killing and postantibiotic effect in oral streptococci are enhanced by platelet microbicidal proteins
SY Lee, SJ Choe |
International Journal of Antimicrobial Agents | 2004 |
|
Antimicrobial peptides: premises and promises
KV Reddy, RD Yedery, C Aranha |
International Journal of Antimicrobial Agents | 2004 |
|
Defensin-mediated innate immunity in the small intestine
AJ Ouellette |
Best Practice & Research Clinical Gastroenterology | 2004 |
|
Lysozyme levels in the nasal secretions of patients with perennial allergic rhinitis and recurrent sinusitis
VC Kalfa, SL Spector, T Ganz, AM Cole |
Annals of Allergy Asthma & Immunology | 2004 |
|
Equine β-defensin-1: full-length cDNA sequence and tissue expression
EG Davis, Y Sang, F Blecha |
Veterinary Immunology and Immunopathology | 2004 |
|
Host defense peptides in burns
L Steinstraesser, Y Oezdogan, S Wang, H Steinau |
Burns | 2004 |
|
Defensins: antimicrobial peptides of vertebrates
T Ganz |
Comptes Rendus Biologies | 2004 |
|
Defensins and Other Antimicrobial Peptides at the Ocular Surface
AM McDermott |
The ocular surface | 2004 |
|
Lesional T cells and dermal dendrocytes in psoriasis plaque express increased levels of granulysin
SP Raychaudhuri, WY Jiang, SK Raychaudhuri, AM Krensky |
Journal of the American Academy of Dermatology | 2004 |
|
Purification and primary structure of two isoforms of arenicin, a novel antimicrobial peptide from marine polychaeta Arenicola marina
TV Ovchinnikova, GM Aleshina, SV Balandin, AD Krasnosdembskaya, ML Markelov, EI Frolova, YF Leonova, AA Tagaev, EG Krasnodembsky, VN Kokryakov |
FEBS Letters | 2004 |
|
Skin Immune System: Cutaneous Immunology and Clinical Immunodermatology, Third Edition
E Guigné, J Revuz, JC Roujeau |
Skin Immune System: Cutaneous Immunology and Clinical Immunodermatology, Third Edition | 2004 |
|
High-level expression and purification of a recombinant hBD-1 fused to LMM protein in Escherichia coli
I Čipáková, E Hostinová, J Gašperı́k, V Velebný |
Protein Expression and Purification | 2004 |
|
Neutrophil Defensins Enhance Lung Epithelial Wound Closure and Mucin Gene Expression In Vitro
J Aarbiou, RM Verhoosel, S Wetering, WI de Boer, JH van Krieken, SV Litvinov, KF Rabe, PS Hiemstra |
American journal of respiratory cell and molecular biology | 2004 |
|
Identification of Defensin α6 as a Potential Biomarker in Colon Adenocarcinoma
MJ Nam, MK Kee, R Kuick, SM Hanash |
The Journal of biological chemistry | 2004 |
|
Dynamic interaction between airway epithelial cells and Staphylococcus aureus
MC da Silva, JM Zahm, D Gras, O Bajolet, M Abely, J Hinnrasky, M Milliot, MC de Assis, C Hologne, N Bonnet, M Merten, MC Plotkowski, E Puchelle |
American journal of physiology. Lung cellular and molecular physiology | 2004 |
|
Neutrophils and keratinocytes in innate immunity-cooperative actions to provide antimicrobial defense at the right time and place
N Borregaard, K Theilgaard-Mönch, JB Cowland, M Ståhle, OE Sørensen |
Journal of leukocyte biology | 2004 |
|
Interactions between neutrophil-derived antimicrobial peptides and airway epithelial cells
S Wetering, GS Tjabringa, PS Hiemstra |
Journal of leukocyte biology | 2004 |
|
Evidence of Positively Selected Sites in Mammalian α-Defensins
DJ Lynn, AT Lloyd, MA Fares, C O'Farrelly |
Molecular Biology and Evolution | 2004 |
|
??-Defensins Released Into Stimulated CD8+ T-Cell Supernatants Are Likely Derived From Residual Granulocytes Within the Irradiated Allogeneic Peripheral Blood Mononuclear Cells Used as Feeders:
GJ Zaharatos, T He, P Lopez, W Yu, J Yu, L Zhang |
Journal of acquired immune deficiency syndromes (1999) | 2004 |
|
Increased Bronchoalveolar Lavage Human ??-Defensin Type 2 in Bronchiolitis Obliterans Syndrome after Lung Transplantation:
DJ Ross, AM Cole, D Yoshioka, AK Park, JA Belperio, H Laks, RM Strieter, JP Lynch, B Kubak, A Ardehali, T Ganz |
Transplantation | 2004 |
|
Proteomic Analysis of Human Tears: Defensin Expression after Ocular Surface Surgery
L Zhou, LQ Huang, RW Beuerman, ME Grigg, SF Li, FT Chew, L Ang, ME Stern, D Tan |
Journal of Proteome Research | 2004 |
|
Differential Effects on Human Immunodeficiency Virus Type 1 Replication by α-Defensins with Comparable Bactericidal Activities
H Tanabe, AJ Ouellette, MJ Cocco, WE Robinson |
Journal of virology | 2004 |
|
Solution Structure of Cryptdin-4, a Mouse Paneth Cell α-Defensin ,
W Jing, HN Hunter, H Tanabe, AJ Ouellette, HJ Vogel |
Biochemistry | 2004 |
|
Paneth Cell α-Defensins from Rhesus Macaque Small Intestine
H Tanabe, J Yuan, MM Zaragoza, S Dandekar, A Henschen-Edman, ME Selsted, AJ Ouellette |
Infection and immunity | 2004 |
|
Engagement of the Pathogen Survival Response Used by Group A Streptococcus to Avert Destruction by Innate Host Defense
JM Voyich, KR Braughton, DE Sturdevant, C Vuong, SD Kobayashi, SF Porcella, M Otto, JM Musser, FR DeLeo |
Journal of immunology (Baltimore, Md. : 1950) | 2004 |
|
Surfactant proteins A and D inhibit the growth of gram negative bacteria by increasing membrane permeability
Huixing Wu, Alexander Kuzmenko, Sijue Wan, Lyndsay Schaffer, Alison Weiss, James H. Fisher, Kwang Sik Kim, Francis X. McCormack |
Journal of Clinical Investigation | 2003 |
|
Antimicrobial Peptides: Current Status and Therapeutic Potential
AR Koczulla, R Bals |
Drugs | 2003 |
|
Mammalian antibiotic peptides
P Šíma, I Trebichavský, K Sigler |
Folia Microbiologica | 2003 |
|
Minidefensins and other antimicrobial peptides: candidate anti-HIV microbicides
AM Cole |
Expert Opinion on Therapeutic Targets | 2003 |
|
α-Defensins in the gastrointestinal tract
RN Cunliffe |
Molecular Immunology | 2003 |
|
Innate immune defences in the human endometrium
AE King, HO Critchley, RW Kelly |
Reproductive biology and endocrinology : RB&E | 2003 |
|
Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3
Z Wu, DM Hoover, D Yang, C Boulègue, F Santamaria, JJ Oppenheim, J Lubkowski, W Lu |
Proceedings of the National Academy of Sciences | 2003 |
|
Trypsin and host defence: a new role for an old enzyme
M Bajaj-Elliott |
Gut | 2003 |
|
Neutrophil granules and secretory vesicles in inflammation
M Faurschou, N Borregaard |
Microbes and Infection | 2003 |
|
Differential expression of alpha- and beta-defensins in human peripheral blood
XM Fang, Q Shu, QX Chen, M Book, HG Sahl, A Hoeft, F Stuber |
European Journal of Clinical Investigation | 2003 |
|
Purification and cDNA cloning of inducible antibacterial peptides fromProtaetia brevitarsis (Coleoptera)
HS Yoon, CS Lee, SY Lee, CS Choi, IH Lee, SM Yeo, HR Kim |
Archives of Insect Biochemistry and Physiology | 2003 |
|
Identification, structure and differential expression of novel pleurocidins clustered on the genome of the winter flounder, Pseudopleuronectes americanus (Walbaum)
SE Douglas, A Patrzykat, J Pytyck, JW Gallant |
European Journal of Biochemistry | 2003 |
|
Localization of human beta-defensin-2 and human neutrophil peptides in superficial folliculitis
T Oono, WK Huh, Y Shirafuji, H Akiyama, K Iwatsuki |
British Journal of Dermatology | 2003 |
|
Quantitative interactions between cryptdin-4 amino terminal variants and membranes
DP Satchell, T Sheynis, S Kolusheva, J Cummings, TK Vanderlick, R Jelinek, ME Selsted, AJ Ouellette |
Peptides | 2003 |
|
Mechanisms of bronchopulmonary C-fiber hypersensitivity induced by cationic proteins
LY Lee, Q Gu |
Pulmonary Pharmacology & Therapeutics | 2003 |
|
Presence of Human β-Defensin-2 in Oral Lichen Planus and its Histamine Releasing Effect
N Mizukawa, K Sawaki, H Nagatsuka, E Yamachika, T Ueno, J Fukunaga, S Takagi, T Sugahara |
Asian Journal of Oral and Maxillofacial Surgery | 2003 |
|
Lung Biology in Health and Disease
N Zamel |
Lung Biology in Health and Disease: Experimental Models and Therapeutic Potential | 2003 |
|
Human β-Defensin-2 Induction in Human Foreskin Keratinocyte by Synergetic Stimulation with Foods and Escherichia Coli
E Nishimura, M Kato, S Hashizume |
Cytotechnology | 2003 |
|
α-Defensins can have anti-HIV activity but are not CD8 cell anti-HIV factors:
CE Mackewicz, J Yuan, P Tran, L Diaz, E Mack, ME Selsted, JA Levy |
AIDS | 2003 |
|
α-Defensin expression during myelopoiesis: identification of cis and trans elements that regulate expression of NP-3 in rat promyelocytes
CM Yamamoto, N Banaiee, NY Yount, B Patel, ME Selsted |
Journal of leukocyte biology | 2003 |
|
Immune defense at the ocular surface
EK Akpek, JD Gottsch |
Eye | 2003 |
|
Structure-Activity Determinants in Paneth Cell α-Defensins: LOSS-OF-FUNCTION IN MOUSE CRYPTDIN-4 BY CHARGE-REVERSAL AT ARGININE RESIDUE POSITIONS
H Tanabe, X Qu, CS Weeks, JE Cummings, S Kolusheva, KB Walsh, R Jelinek, TK Vanderlick, ME Selsted, AJ Ouellette |
The Journal of biological chemistry | 2003 |
|
Defensins: antimicrobial peptides of innate immunity
T Ganz |
Nature Reviews Immunology | 2003 |
|
Antimicrobial Peptides: Potential Use in Skin Infections
H Ulvatne |
American Journal of Clinical Dermatology | 2003 |
|
The Macrophage as Therapeutic Target
S Gordon |
2003 | |
|
Staphylococcus aureus Susceptibility to Innate Antimicrobial Peptides, β-Defensins and CAP18, Expressed by Human Keratinocytes
K Midorikawa, K Ouhara, H Komatsuzawa, T Kawai, S Yamada, T Fujiwara, K Yamazaki, K Sayama, MA Taubman, H Kurihara, K Hashimoto, M Sugai |
Infection and immunity | 2003 |
|
Enteric Salmonella Infection Inhibits Paneth Cell Antimicrobial Peptide Expression
NH Salzman, MM Chou, H de Jong, L Liu, EM Porter, Y Paterson |
Infection and immunity | 2003 |
|
FcγRIIIb Allele-Sensitive Release of α-Defensins: Anti-Neutrophil Cytoplasmic Antibody-Induced Release of Chemotaxins
S Tanaka, JC Edberg, W Chatham, G Fassina, RP Kimberly |
Journal of immunology (Baltimore, Md. : 1950) | 2003 |
|
Productive Folding of Human Neutrophil α-Defensins in Vitro without the Pro-peptide
Z Wu, R Powell, W Lu |
Journal of the American Chemical Society | 2003 |
|
From pro defensins to defensins: synthesis and characterization of human neutrophil pro α-defensin-1 and its mature domain: Human neutrophil α-defensin
Z Wu, A Prahl, R Powell, B Ericksen, J Lubkowski, W Lu |
Journal of Peptide Research | 2003 |
|
Antimicrobial Characterization of Human β-Defensin 3 Derivatives
DM Hoover, Z Wu, K Tucker, W Lu, J Lubkowski |
Antimicrobial agents and chemotherapy | 2003 |
|
Decreased excretion of antimicrobial proteins and peptides in saliva of patients with oral candidiasis: Antimicrobial peptides in saliva
T Tanida, T Okamoto, A Okamoto, H Wang, T Hamada, E Ueta, T Osaki |
Journal of Oral Pathology and Medicine | 2003 |
|
Microbial Pathogenesis and the Intestinal Epithelial Cell
GA Hecht |
2003 | |
|
Human beta-Defensin-2 Induction in Human Foreskin Keratinocyte by Synergetic Stimulation with Foods and Escherichia Coli.
Nishimura E, Kato M, Hashizume S |
Cytotechnology | 2003 |
|
The cell-mediated immune reaction in the cutaneous lesion of chromoblastomycosis and their correlation with different clinical forms of the disease.
d'Avila SC, Pagliari C, Duarte MI |
Mycopathologia | 2003 |
|
In vivo microdialysis for determination of nasal liquid ion composition
BR Grubb, JL Chadburn, RC Boucher |
American journal of physiology. Cell physiology | 2002 |
|
Human α-Defensins HNPs-1, -2, and -3 in Renal Cell Carcinoma
CA Müller, J Markovic-Lipkovski, T Klatt, J Gamper, G Schwarz, H Beck, M Deeg, H Kalbacher, S Widmann, JT Wessels, V Becker, GA Müller, T Flad |
The American Journal of Pathology | 2002 |
|
Tumor necrosis factor alpha stimulates killing of Mycobacterium tuberculosis by human neutrophils
KO Kisich, M Higgins, G Diamond, L Heifets |
Infection and immunity | 2002 |
|
Expression of beta-defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells
LA Duits, B Ravensbergen, M Rademaker, PS Hiemstra, PH Nibbering |
Immunology | 2002 |
|
Identification and genetic characterization of PmrA-regulated genes and genes involved in polymyxin B resistance in Salmonella enterica serovar typhimurium
R Tamayo, SS Ryan, AJ McCoy, JS Gunn |
Infection and immunity | 2002 |
|
The use of antimicrobial peptides in ophthalmology: an experimental study in corneal preservation and the management of bacterial keratitis
MJ Mannis |
Transactions of the American Ophthalmological Society | 2002 |
|
Human alpha-defensins HNPs-1, -2, and -3 in renal cell carcinoma: influences on tumor cell proliferation
CA Müller, J Markovic-Lipkovski, T Klatt, J Gamper, G Schwarz, H Beck, M Deeg, H Kalbacher, S Widmann, JT Wessels, V Becker, GA Müller, T Flad |
The American Journal of Pathology | 2002 |
|
Thermolysin-linearized microcin J25 retains the structured core of the native macrocyclic peptide and displays antimicrobial activity
A Blond, M Cheminant, D Destoumieux-Garzón, I Ségalas-Milazzo, J Peduzzi, C Goulard, S Rebuffat |
European Journal of Biochemistry | 2002 |
|
New agents for the treatment of systemic fungal infections – current status
JH Rex, S Arikan |
Expert Opinion on Emerging Drugs | 2002 |
|
Immunohistochemical study on expression of -defensin and -defensin-2 in human buccal epithelia with candidiasis
K Sawaki, N Mizukawa, T Yamaai, J Fukunaga, T Sugahara |
Oral Diseases | 2002 |
|
Human beta-Defensin-2 Production in Keratinocytes is Regulated by Interleukin-1, Bacteria, and the State of Differentiation
AY Liu, D Destoumieux, AV Wong, CH Park, EV Valore, L Liu, T Ganz |
Journal of Investigative Dermatology | 2002 |
|
Immunolocalization of clavanins in Styela clava hemocytes
LP Menzel, IH Lee, B Sjostrand, RI Lehrer |
Developmental & Comparative Immunology | 2002 |
|
Comparative study on characteristics of lysozymes from the hemolymph of three lepidopteran larvae, Galleria mellonella, Bombyx mori, Agrius convolvuli
KH Yu, KN Kim, JH Lee, HS Lee, SH Kim, KY Cho, MH Nam, IH Lee |
Developmental & Comparative Immunology | 2002 |
|
Comprehensive gene expression analysis of human NK cells and CD8+ T lymphocytes
A Obata-Onai, S Hashimoto, N Onai, M Kurachi, S Nagai, K Shizuno, T Nagahata, K Matsushima |
International Immunology | 2002 |
|
Histamine Release from Rat Mast Cells Induced by Human α-Defensin-1 Present in Jaw Cyst Fluid
N Mizukawa, K Sawaki, M Kamio, J Fukunaga, T Ueno, S Takagi, T Sugahara |
Asian Journal of Oral and Maxillofacial Surgery | 2002 |
|
Biology and clinical relevance of naturally occurring antimicrobial peptides
RL Gallo, M Murakami, T Ohtake, M Zaiou |
Journal of Allergy and Clinical Immunology | 2002 |
|
Halocidin: a new antimicrobial peptide from hemocytes of the solitary tunicate, Halocynthia aurantium
WS Jang, KN Kim, YS Lee, MH Nam, IH Lee |
FEBS Letters | 2002 |
|
The Role of Defensins in Lung Biology and Therapy
AM Cole, AJ Waring |
American Journal of Respiratory Medicine | 2002 |
|
Antimicrobial components of vaginal fluid
EV Valore, CH Park, SL Igreti, T Ganz |
American Journal of Obstetrics and Gynecology | 2002 |
|
Antimicrobial factors in the cervical mucus plug
M Hein, EV Valore, RB Helmig, N Uldbjerg, T Ganz |
American Journal of Obstetrics and Gynecology | 2002 |
|
Defensin-rich granules of human neutrophils: characterization of secretory properties
M Faurschou, OE Sørensen, AH Johnsen, J Askaa, N Borregaard |
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2002 |
|
Contribution of Human -Defensin 1, 2, and 3 to the Anti-HIV-1 Activity of CD8 Antiviral Factor
L Zhang, W Yu, T He, J Yu, RE Caffrey, EA Dalmasso, S Fu, T Pham, J Mei, JJ Ho, W Zhang, P Lopez, DD Ho |
Science | 2002 |
|
The Structure of Human Macrophage Inflammatory Protein-3α/CCL20: LINKING ANTIMICROBIAL AND CC CHEMOKINE RECEPTOR-6-BINDING ACTIVITIES WITH HUMAN β-DEFENSINS
DM Hoover, C Boulègue, D Yang, JJ Oppenheim, K Tucker, W Lu, J Lubkowski |
The Journal of biological chemistry | 2002 |
|
Antimicrobial Defensin Peptides of the Human Nasal Mucosa
SH Lee, JE Kim, HM Lee, HH Lim, JO Choi |
The Annals of otology, rhinology, and laryngology | 2002 |
|
Cationic Polypeptides Are Required for Antibacterial Activity of Human Airway Fluid
AM Cole, HI Liao, O Stuchlik, J Tilan, J Pohl, T Ganz |
Journal of immunology (Baltimore, Md. : 1950) | 2002 |
|
Antimicrobial Peptides Initiate IL-1β Posttranslational Processing: A Novel Role Beyond Innate Immunity
DG Perregaux, K Bhavsar, L Contillo, J Shi, CA Gabel |
Journal of immunology (Baltimore, Md. : 1950) | 2002 |
|
Identification of Multiple Novel Epididymis-Specific β-Defensin Isoforms in Humans and Mice
Y Yamaguchi, T Nagase, R Makita, S Fukuhara, T Tomita, T Tominaga, H Kurihara, Y Ouchi |
Journal of immunology (Baltimore, Md. : 1950) | 2002 |
|
Cutaneous Injury Induces the Release of Cathelicidin Anti-Microbial Peptides Active Against Group A Streptococcus
RA Dorschner, VK Pestonjamasp, S Tamakuwala, T Ohtake, J Rudisill, V Nizet, B Agerberth, GH Gudmundsson, RL Gallo |
Journal of Investigative Dermatology | 2001 |
|
Adenoviral augmentation of elafin protects the lung against acute injury mediated by activated neutrophils and bacterial infection
AJ Simpson, WA Wallace, ME Marsden, JR Govan, DJ Porteous, C Haslett, JM Sallenave |
Journal of immunology (Baltimore, Md. : 1950) | 2001 |
|
Human defensin 5 is stored in precursor form in normal Paneth cells and is expressed by some villous epithelial cells and by metaplastic Paneth cells in the colon in inflammatory bowel disease
RN Cunliffe, FR Rose, J Keyte, L Abberley, WC Chan, YR Mahida |
Gut | 2001 |
|
Innate antimicrobial peptide protects the skin from invasive bacterial infection
V Nizet, T Ohtake, X Lauth, J Trowbridge, J Rudisill, RA Dorschner, V Pestonjamasp, J Piraino, K Huttner, RL Gallo |
Nature | 2001 |
|
Inhibition of hBD-3, but Not hBD-1 and hBD-2, mRNA Expression by Corticosteroids
LA Duits, M Rademaker, B Ravensbergen, MA van Sterkenburg, E Strijen, PS Hiemstra, PH Nibbering |
Biochemical and Biophysical Research Communications | 2001 |
|
Defensins ??? innate immunity at the epithelial frontier
K Fellermann, EF Stange |
European Journal of Gastroenterology & Hepatology | 2001 |
|
Human α-defensin 1 (HNP-1) inhibits adenoviral infection in vitro
A Bastian, H Schäfer |
Regulatory Peptides | 2001 |
|
Human antimicrobial peptides :
HC Ryley |
Reviews in Medical Microbiology | 2001 |
|
Calcitermin, a novel antimicrobial peptide isolated from human airway secretions
AM Cole, YH Kim, S Tahk, T Hong, P Weis, AJ Waring, T Ganz |
FEBS Letters | 2001 |
|
Peptide Antibiotics: Discovery Modes Of Action And Applications
D Andreu, L Rivas |
Peptide Antibiotics: Discovery Modes Of Action And Applications | 2001 |
|
Modulation of Mouse Paneth Cell α-Defensin Secretion by mIKCa1, a Ca 2+ -activated, Intermediate Conductance Potassium Channel
T Ayabe, H Wulff, D Darmoul, MD Cahalan, KG Chandy, AJ Ouellette |
The Journal of biological chemistry | 2001 |
|
Groups IV, V, and X Phospholipases A 2 s in Human Neutrophils: ROLE IN EICOSANOID PRODUCTION AND GRAM-NEGATIVE BACTERIAL PHOSPHOLIPID HYDROLYSIS
N Degousee, F Ghomashchi, E Stefanski, A Singer, BP Smart, N Borregaard, R Reithmeier, TF Lindsay, C Lichtenberger, W Reinisch, G Lambeau, J Arm, J Tischfield, MH Gelb, BB Rubin |
The Journal of biological chemistry | 2001 |
|
A Novel Mouse β-Defensin, mBD-6, Predominantly Expressed in Skeletal Muscle
Y Yamaguchi, S Fukuhara, T Nagase, T Tomita, S Hitomi, S Kimura, H Kurihara, Y Ouchi |
The Journal of biological chemistry | 2001 |
|
Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils
DJ Elzi, AJ Bjornsen, T MacKenzie, TH Wyman, CC Silliman |
American journal of physiology. Cell physiology | 2001 |
|
The Solution Structures of the Human β-Defensins Lead to a Better Understanding of the Potent Bactericidal Activity of HBD3 against Staphylococcus aureus
DJ Schibli, HN Hunter, V Aseyev, TD Starner, JM Wiencek, PB McCray, BF Tack, HJ Vogel |
The Journal of biological chemistry | 2001 |
|
Antimicrobial peptides: a potential role in ocular therapy
Y Aliwarga, EB Hume, J Lan, MD Willcox |
Clinical & Experimental Ophthalmology | 2001 |
|
Diversity in Antistaphylococcal Mechanisms among Membrane-Targeting Antimicrobial Peptides
JD Clements, SP Koo, AS Bayer, MR Yeaman |
Infection and immunity | 2001 |
|
Interaction of pleurocidin and its analogs with phospholipid membrane and their antibacterial activity: Pleurocidin-phospholipid membrane interaction
K Yoshida, Y Mukai, T Niidome, C Takashi, Y Tokunaga, T Hatakeyama, H Aoyagi |
Journal of Peptide Research | 2001 |
|
Biologically Active Proteins from Natural Product Extracts
BR O'Keefe |
Journal of Natural Products | 2001 |
|
Three-Dimensional Structure of RTD-1, a Cyclic Antimicrobial Defensin from Rhesus Macaque Leukocytes ,
M Trabi, HJ Schirra, DJ Craik |
Biochemistry | 2001 |
|
Immunology of Infectious Diseases
SH Kaufmann, A Sher, R Ahmed |
2001 | |
|
Toward Proteomics in Uroscopy: Urinary Protein Profiles after Radiocontrast Medium Administration
DJ Hampel, C Sansome, MA Sha, S Brodsky, WE Lawson, MS Goligorsky |
Journal of the American Society of Nephrology : JASN | 2001 |
|
Cutting Edge: IFN-Inducible ELR − CXC Chemokines Display Defensin-Like Antimicrobial Activity
AM Cole, T Ganz, AM Liese, MD Burdick, L Liu, RM Strieter |
Journal of immunology (Baltimore, Md. : 1950) | 2001 |
|
Expression of Defensin Antimicrobial Peptides in the Peritoneal Cavity of Patients on Peritoneal Dialysis
KH Zarrinkalam, DI Leavesley, JM Stanley, GJ Atkins, RJ Faull |
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis | 2001 |
|
Stimulation of bacterial adherence by neutrophil defensins varies among bacterial species but not among host cell types
AD Gorter, PS Hiemstra, S Bentzmann, S Wetering, J Dankert, L Alphen |
FEMS Immunology & Medical Microbiology | 2000 |
|
Mechanisms of the in vitro fungicidal effects of human neutrophils against Penicillium marneffei induced by granulocyte-macrophage colony-stimulating factor (GM-CSF)
N Kudeken, K Kawakami, A Saito |
Clinical & Experimental Immunology | 2000 |
|
Epithelial antimicrobial peptides in host defense against infection
R Bals |
Respiratory Research | 2000 |
|
Large-scale synthesis and functional elements for the antimicrobial activity of defensins
PA Raj, KJ Antonyraj, T Karunakaran |
Biochemical Journal | 2000 |
|
Androctonin, a hydrophilic disulphide-bridged non-haemolytic anti-microbial peptide: a plausible mode of action
C Hetru, L Letellier, Z Oren, JA Hoffmann, Y Shai |
Biochemical Journal | 2000 |
|
Antifungal peptides: potential candidates for the treatment of fungal infections
AJ de Lucca |
Expert Opinion on Investigational Drugs | 2000 |
|
New agents for treatment of systemic fungal infections
S Arikan, JH Rex |
Expert Opinion on Emerging Drugs | 2000 |
|
Simultaneous cytofluorometric measurement of phagocytosis, burst production and killing of human phagocytes using Candida albicans and Staphylococcus aureus as target organisms
HR Salih, L Husfeld, D Adam |
Clinical Microbiology and Infection | 2000 |
|
Synthesis, microbicidal activity, and solution structure of the dodecapeptide from bovine neutrophils
PA Raj, T Karunakaran, DK Sukumaran |
Biopolymers | 2000 |
|
Sensitivity of Actinobacillus actinomycetemcomitans and Capnocytophaga spp. to the bactericidal action of LL-37: a cathelicidin found in human leukocytes and epithelium
D Tanaka, KT Miyasaki, RI Lehrer |
Oral Microbiology and Immunology | 2000 |
|
Determination of defensin HNP-1, HNP-2, and HNP-3 in human saliva by using LC/MS
C Goebel, LG Mackay, ER Vickers, LE Mather |
Peptides | 2000 |
|
Recombinant granulocyte colony-stimulating factor induces production of human neutrophil peptides in lung cancer patients with neutropenia
J Ashitani, M Nakazato, H Mukae, H Taniguchi, Y Date, S Matsukura |
Regulatory Peptides | 2000 |
|
Original involvement of antimicrobial peptides in mussel innate immunity
G Mitta, F Vandenbulcke, P Roch |
FEBS Letters | 2000 |
|
Antibacterial properties and partial cDNA sequences of cecropin-like antibacterial peptides from the common cutworm, Spodoptera litura
CS Choi, IH Lee, E Kim, SI Kim, HK Kim |
Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology | 2000 |
|
HIV: reactive oxygen species, enveloped viruses and hyperbaric oxygen
MA Baugh |
Medical Hypotheses | 2000 |
|
Detection of human α-defensin-1, an antimicrobial peptide, in the fluid of jaw cysts
N Mizukawa, K Sugiyama, T Ueno, K Mishima, S Takagi, T Sugahara |
Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology | 2000 |
|
Thrombocidins, Microbicidal Proteins from Human Blood Platelets, Are C-terminal Deletion Products of CXC Chemokines
J Krijgsveld, SA Zaat, J Meeldijk, PA van Veelen, G Fang, B Poolman, E Brandt, JE Ehlert, AJ Kuijpers, GH Engbers, J Feijen, J Dankert |
The Journal of biological chemistry | 2000 |
|
Characterization of Histatin 5 with Respect to Amphipathicity, Hydrophobicity, and Effects on Cell and Mitochondrial Membrane Integrity Excludes a Candidacidal Mechanism of Pore Formation
EJ Helmerhorst, W Hof, P Breeuwer, EC Veerman, T Abee, RF Troxler, AV Amerongen, FG Oppenheim |
The Journal of biological chemistry | 2000 |
|
Inherited Neutrophil Disorders
MC Dinauer, JA Lekstrom-Himes, DC Dale |
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program | 2000 |
|
Role of CCAAT/Enhancer-Binding Protein Site in Transcription of Human Neutrophil Peptide-1 and -3 Defensin Genes
Y Tsutsumi-Ishii, T Hasebe, I Nagaoka |
Journal of immunology (Baltimore, Md. : 1950) | 2000 |
|
Human Neutrophil-Mediated Nonoxidative Antifungal Activity against Cryptococcus neoformans
WA Petri, SS Mambula, ER Simons, R Hastey, ME Selsted, SM Levitz |
Infection and immunity | 2000 |
|
Identification of Constituents of Human Neutrophil Azurophil Granules That Mediate Fungistasis againstHistoplasma capsulatum
JM Mansfield, SL Newman, L Gootee, JE Gabay, ME Selsted |
Infection and immunity | 2000 |
|
Differential distribution and defence involvement of antimicrobial peptides in mussel
G Mitta, F Vandenbulcke, T Noel, B Romestand, JC Beauvillain, M Salzet, P Roch |
Journal of cell science | 2000 |
|
Antibiotic peptides from higher eukaryotes: biology and applications
T Ganz, RI Lehrer |
Molecular Medicine Today | 1999 |
|
Defensins impair phagocytic killing by neutrophils in biomaterial-related infection
SS Kaplan, RP Heine, RL Simmons |
Infection and immunity | 1999 |
|
Defensins and innate host defence of the gastrointestinal tract
CL Bevins, E Martin-Porter, T Ganz |
Gut | 1999 |
|
Neutrophils aid in protection of the vaginal mucosae of immune mice against challenge with herpes simplex virus type 2
GN Milligan |
Journal of virology | 1999 |
|
Antimicrobial defensin peptides of the human ocular surface
RJ Haynes, PJ Tighe, HS Dua |
The British journal of ophthalmology | 1999 |
|
Detection of cryptdin in mouse skin
Y Shirafuji, T Oono, H Kanzaki, S Hirakawa, J Arata |
Clinical and diagnostic laboratory immunology | 1999 |
|
In vitro antibacterial activities of platelet microbicidal protein and neutrophil defensin against Staphylococcus aureus are influenced by antibiotics differing in mechanism of action
YQ Xiong, MR Yeaman, AS Bayer |
Antimicrobial agents and chemotherapy | 1999 |
|
Mechanisms for induction of acquired host immunity by neutrophil peptide defensins
JW Lillard, PN Boyaka, O Chertov, JJ Oppenheim, JR McGhee |
Proceedings of the National Academy of Sciences | 1999 |
|
Antifungal peptides: novel therapeutic compounds against emerging pathogens
AJ de Lucca, TJ Walsh |
Antimicrobial agents and chemotherapy | 1999 |
|
Cecropin D-like antibacterial peptides from the sphingid moth,Agrius convolvuli
IH Lee, KY Chang, CS Choi, HR Kim |
Archives of Insect Biochemistry and Physiology | 1999 |
|
Immunomagnetic recovery of human neutrophil defensins from the human gingival crevice
MS McKay, E Olson, MA Hesla, A Panyutich, T Ganz, S Perkins, EF Rossomando |
Oral Microbiology and Immunology | 1999 |
|
Defensin-1, an antimicrobial peptide present in the saliva of patients with oral diseases
N Mizukawa, K Sugiyama, T Ueno, K Mishima, S Takagi, T Sugahara |
Oral Diseases | 1999 |
|
Interleukin 12 and innate molecules for enhanced mucosal immunity
PN Boyaka, JW Lillard, J McGhee |
Immunologic Research | 1999 |
|
Distinct granule populations in human neutrophils and lysosomal organelles identified by immuno-electron microscopy
DF Bainton |
Journal of Immunological Methods | 1999 |
|
Processing and targeting of granule proteins in human neutrophils
U Gullberg, N Bengtsson, E Bülow, D Garwicz, A Lindmark, I Olsson |
Journal of Immunological Methods | 1999 |
|
THE GUT'S ROLE IN METABOLISM, MUCOSAL BARRIER FUNCTION, AND GUT IMMUNOLOGY
RC DeWitt, KA Kudsk |
Infectious Disease Clinics of North America | 1999 |
|
Pore-forming properties and antibacterial activity of proteins extracted from epidermal mucus of fish
N Ebran, S Julien, N Orange, P Saglio, C Lemaı̂tre, G Molle |
Comparative Biochemistry and Physiology - Part A Molecular & Integrative Physiology | 1999 |
|
Antimicrobial Peptides as Mediators of Epithelial Host Defense
KM Huttner, CL Bevins |
Pediatric Research | 1999 |
|
Elafin (elastase-specific inhibitor) has anti-microbial activity against Gram-positive and Gram-negative respiratory pathogens
AJ Simpson, AI Maxwell, JR Govan, C Haslett, JM Sallenave |
FEBS Letters | 1999 |
|
Chronic Lung Disease in Early Infancy
D Riley |
Chronic Lung Disease in Early Infancy | 1999 |
|
Levels of human defensin-1, an antimicrobial peptide, in saliva of patients with oral inflammation
N Mizukawa, K Sugiyama, T Ueno, K Mishima, S Takagi, T Sugahara |
Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology | 1999 |
|
Alkaline Phosphatase, Defensin Gene Expression and Effect of Myeloid Cell Growth Factors in Normal and Leukemic Cells
T Tsuruta, K Tani, A Hoshikaa, S Asano |
Leukemia & Lymphoma | 1999 |
|
Lentivirus-derived antimicrobial peptides: increased potency by sequence engineering and dimerization
SB Tencza, DJ Creighton, T Yuan, HJ Vogel, RC Montelaro, TA Mietzner |
Journal of Antimicrobial Chemotherapy | 1999 |
|
Cloning and Expression of Bovine Neutrophil β-Defensins: BIOSYNTHETIC PROFILE DURING NEUTROPHILIC MATURATION AND LOCALIZATION OF MATURE PEPTIDE TO NOVEL CYTOPLASMIC DENSE GRANULES
NY Yount, J Yuan, A Tarver, T Castro, G Diamond, PA Tran, JN Levy, C McCullough, JS Cullor, CL Bevins, ME Selsted |
The Journal of biological chemistry | 1999 |
|
Antibacterial and antifungal drug discovery
A Persidis |
Nature Biotechnology | 1999 |
|
Sepsis and Organ Dysfunction
AE Baue, G Berlot, A Gullo, JL Vincent |
1999 | |
|
Innate Antimicrobial Activity of Nasal Secretions
JR McGhee, AM Cole, P Dewan, T Ganz |
Infection and immunity | 1999 |
|
Innate Antimicrobial Activity of Nasal Secretions
JR McGhee, AM Cole, P Dewan, T Ganz |
Infection and immunity | 1999 |
|
Innate Antimicrobial Activity of Nasal Secretions
JR McGhee, AM Cole, P Dewan, T Ganz |
Infection and immunity | 1999 |
|
Defensins Impair Phagocytic Killing by Neutrophils in Biomaterial-Related Infection
RN Moore, SS Kaplan, RP Heine, RL Simmons |
Infection and immunity | 1999 |
|
Membrane Thinning Effect of the β-Sheet Antimicrobial Protegrin
WT Heller, AJ Waring, RI Lehrer, TA Harroun, TM Weiss, L Yang, HW Huang |
Biochemistry | 1999 |
|
Phylogenetic Perspectives in Innate Immunity
JA Hoffmann, FC Kafatos, CA Janeway, RA Ezekowitz |
Science | 1999 |
|
Antifungal Peptides: Novel Therapeutic Compounds against Emerging Pathogens
AJ Lucca, TJ Walsh |
Antimicrobial agents and chemotherapy | 1999 |
|
Laccase Protects Cryptococcus neoformans from Antifungal Activity of Alveolar Macrophages
TR Kozel, L Liu, RP Tewari, PR Williamson |
Infection and immunity | 1999 |
|
Isolation, Characterization, cDNA Cloning, and Antimicrobial Properties of Two Distinct Subfamilies of α-Defensins from Rhesus Macaque Leukocytes
TR Kozel, YQ Tang, J Yuan, CJ Miller, ME Selsted |
Infection and immunity | 1999 |
|
Interleukin 12 and innate molecules for enhanced mucosal immunity.
Boyaka PN, Lillard JW Jr, McGhee J |
Immunologic research | 1999 |
|
Human beta-defensin-1: an antimicrobial peptide of urogenital tissues
EV Valore, CH Park, AJ Quayle, KR Wiles, PB McCray, T Ganz |
Journal of Clinical Investigation | 1998 |
|
Antibacterial activity of human neutrophil defensins in experimental infections in mice is accompanied by increased leukocyte accumulation
MM Welling, PS Hiemstra, MT van Barselaar, A Paulusma-Annema, PH Nibbering, EK Pauwels, W Calame |
Journal of Clinical Investigation | 1998 |
|
Gene expression, immunolocalization, and secretion of human defensin-5 in human female reproductive tract
AJ Quayle, EM Porter, AA Nussbaum, YM Wang, C Brabec, KP Yip, SC Mok |
The American Journal of Pathology | 1998 |
|
Antimicrobial Peptides: An Emerging Concept in Cutaneous Biology
RL Gallo, KM Huttner |
Journal of Investigative Dermatology | 1998 |
|
Dermaseptin, a Peptide Antibiotic, Stimulates Microbicidal Activities of Polymorphonuclear Leukocytes
B Ammar, A Périanin, A Mor, G Sarfati, M Tissot, P Nicolas, JP Giroud, M Roch-Arveiller |
Biochemical and Biophysical Research Communications | 1998 |
|
Killing of Fusobacterium nucleaturn, Porphyromonas gingivalis and Prevotella intermedia by protegrins
KT Miyasaki, R Iofel, A Oren, T Huynh, RI Lehrer |
Journal of Periodontal Research | 1998 |
|
β-sheet antibiotic peptides as potential dental therapeutics1Presented in part at the symposium ‘Impact of bacterial antibiotic resistance: What is the relevance’, University of Washington, Seattle, Sep 5–6, 19961
KT Miyasaki, RI Lehrer |
International Journal of Antimicrobial Agents | 1998 |
|
Enteric Defensin Expression in Necrotizing Enterocolitis
NH Salzman, RA Polin, MC Harris, E Ruchelli, A Hebra, S Zirin-Butler, A Jawad, EM Porter, CL Bevins |
Pediatric Research | 1998 |
|
Isolation of human intestinal defensins from ileal neobladder urine
EM Porter, MA Poles, JS Lee, J Naitoh, CL Bevins, T Ganz |
FEBS Letters | 1998 |
|
β-Defensins: Endogenous Antibiotics of the Innate Host Defense Response
G Diamond, CL Bevins |
Clinical Immunology and Immunopathology | 1998 |
|
Peptide antibiotics as a factors of mammalian immunity
PV Pogrebnoj |
Biopolymers and Cell | 1998 |
|
Neutrophil chemotaxis induced by corneal epithelial cells after herpes simplex virus type 1 infection
D Miyazaki, Y Inoue, K Araki-Sasaki, Y Shimomura, Y Tano, K Hayashi |
Current Eye Research | 1998 |
|
Antimicrobial Peptide Expression Is Developmentally Regulated in the Ovine Gastrointestinal Tract
KM Huttner, DJ Brezinski-Caliguri, MM Mahoney, G Diamond |
The Journal of nutrition | 1998 |
|
Azurophilic Granules of Human Neutrophilic Leukocytes Are Deficient in Lysosome-Associated Membrane Proteins but Retain the Mannose 6-Phosphate Recognition Marker
AM Cieutat, P Lobel, JT August, L Kjeldsen, H Sengeløv, N Borregaard, DF Bainton |
Blood | 1998 |
|
Three-Dimensional Solution Structure of Lactoferricin B, an Antimicrobial Peptide Derived from Bovine Lactoferrin
PM Hwang, N Zhou, , CH Arrowsmith, HJ Vogel |
Biochemistry | 1998 |
|
Cryptococcus neoformans
A Casadevall, JR Perfect |
1998 | |
|
Biosynthesis, processing and sorting of neutrophil proteins: insight into neutrophil granule development
U Gullberg, E Andersson, D Garwicz, A Lindmark, I Olsson |
European Journal of Haematology | 1997 |
|
Development of Neutrophil Granule Diversity
N Borregaard |
Annals of the New York Academy of Sciences | 1997 |
|
Porcine polymorphonuclear leukocytes generate extracellular microbicidal activity by elastase-mediated activation of secreted proprotegrins
A Panyutich, J Shi, PL Boutz, C Zhao, T Ganz |
Infection and immunity | 1997 |
|
Immunohistochemical localization of defensin in human coronary vessels
ES Barnathan, PN Raghunath, JE Tomaszewski, T Ganz, DB Cines, HA al-R |
The American Journal of Pathology | 1997 |
|
Antimicrobial action of rabbit leukocyte CAP18(106-137)
DJ Mason, R Dybowski, JW Larrick, VA Gant |
Antimicrobial agents and chemotherapy | 1997 |
|
Intracellular Location of SNAP-25 in Human Neutrophils
S Nabokina, G Egea, J Blasi, F Mollinedo |
Biochemical and Biophysical Research Communications | 1997 |
|
Gloverin, an Antibacterial Protein from the Immune Hemolymph of Hyalophora Pupae
A Axen, A Carlsson, A Engstrom, H Bennich |
European Journal of Biochemistry | 1997 |
|
The Human β-Defensin-1 and α-Defensins Are Encoded by Adjacent Genes: Two Peptide Families with Differing Disulfide Topology Share a Common Ancestry
L Liu, C Zhao, HH Heng, T Ganz |
Genomics | 1997 |
|
Defensins purified from human granulocytes bind C1q and activate the classical complement pathway like the transmenbrane glycoprotein gq41 of HIV-1
Z Proha´szka, K Ne´met, P Csermely, F Hudecz, G Mezo˜, G Fu¨st |
Molecular Immunology | 1997 |
|
Are free radicals responsible for endothelial cell killing of Staphylococcus aureus?
B Zhang, M Centra, GL Cao, RE Ratych, JB Domachowske, HL Malech, GM Rosen |
Immunology Letters | 1997 |
|
Semidry Electroblotting of Peptides and Proteins from Acid–Urea Polyacrylamide Gels
MS Wang, JS Pang, ME Selsted |
Analytical Biochemistry | 1997 |
|
Granules of the human neutrophilic polymorphonuclear leukocyte
N Borregaard, JB Cowland |
Blood | 1997 |
|
Styelins, Broad-Spectrum Antimicrobial Peptides from the Solitary Tunicate, Styela clava
IH Lee, Y Cho, RI Lehrer |
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology | 1997 |
|
The Human Antibacterial Cathelicidin, hCAP-18, Is Synthesized in Myelocytes and Metamyelocytes and Localized to Specific Granules in Neutrophils
O Sørensen, K Arnljots, JB Cowland, DF Bainton, N Borregaard |
Blood | 1997 |
|
Broad-spectrum antimicrobial activity of human intestinal defensin 5
EM Porter, E van Dam, EV Valore, T Ganz |
Infection and immunity | 1997 |
|
Frontiers in research on cystic fibrosis: understanding its molecular and chemical basis and relationship to the pathogenesis of the disease
Y H Ko, P L Pedersen |
Journal of Bioenergetics and Biomembranes | 1997 |
|
Electrophoretic detection of myeloperoxidase, protease, lactoferrin and lysozyme in buffalo polymorphonuclear granular acid extracts
S C Roy, V K Singh, T More |
Veterinary Research Communications | 1997 |
|
Intramolecular inhibition of human defensin HNP-1 by its propiece
EV Valore, E Martin, SS Harwig, T Ganz |
Journal of Clinical Investigation | 1996 |
|
Neutrophil-mediated suppression of virus replication after herpes simplex virus type 1 infection of the murine cornea
TM Tumpey, SH Chen, JE Oakes, RN Lausch |
Journal of virology | 1996 |
|
PhoP-PhoQ activates transcription of pmrAB, encoding a two-component regulatory system involved in Salmonella typhimurium antimicrobial peptide resistance
JS Gunn, SI Miller |
Journal of bacteriology | 1996 |
|
Evaluation of susceptibility of gram-positive and -negative bacteria to human defensins by using radial diffusion assay
H Takemura, M Kaku, S Kohno, Y Hirakata, H Tanaka, R Yoshida, K Tomono, H Koga, A Wada, T Hirayama, S Kamihira |
Antimicrobial agents and chemotherapy | 1996 |
|
In vitro activity of the antimicrobial peptides human and rabbit defensins and porcine leukocyte protegrin against Mycobacterium tuberculosis
Y Miyakawa, P Ratnakar, AG Rao, ML Costello, O Mathieu-Costello, RI Lehrer, A Catanzaro |
Infection and immunity | 1996 |
|
Intracellular survival of Burkholderia pseudomallei
AL Jones, TJ Beveridge, DE Woods |
Infection and immunity | 1996 |
|
Intramolecular Disulfide Bonds Enhance the Antimicrobial and Lytic Activities of Protegrins at Physiological Sodium Chloride Concentrations
SS Harwig, A Waring, HJ Yang, Y Cho, L Tan, RI Lehrer |
European Journal of Biochemistry | 1996 |
|
Purification and Characterization of a Proline-Rich Antibacterial Peptide, with Sequence Similarity to Bactenecin-7, from the Haemocytes of the Shore Crab, Carcinus Maenas
D Schnapp, GD Kemp, VJ Smith |
European Journal of Biochemistry | 1996 |
|
Endogenous Vertebrate Antibiotics
RI Lehrer, T Ganz |
Annals of the New York Academy of Sciences | 1996 |
|
Some biochemical responses of buffalo PMN cells to various stimuli
S Sarmah, T More |
Comparative Immunology, Microbiology and Infectious Diseases | 1996 |
|
Cloning and expression of human defensin HNP-1 genomic DNA in Escherichia coli
H Takemura, M Kaku, S Kohno, H Tanaka, R Yoshida, K Ishida, R Mizukane, H Koga, K Hara, U Toshiaki, T Ezaki |
Journal of Microbiological Methods | 1996 |
|
The Isolation and Characterization of a Novel Corticostatin/Defensin-like Peptide from the Kidney
A Bateman, RJ MacLeod, P Lembessis, J Hu, F Esch, S Solomon |
The Journal of biological chemistry | 1996 |
|
Defensin Modulates Tissue-type Plasminogen Activator and Plasminogen Binding to Fibrin and Endothelial Cells
AA Higazi, T Ganz, K Kariko, DB Cines |
The Journal of biological chemistry | 1996 |
|
Delineation of an Active Fragment and Poly( l -proline) II Conformation for Candidacidal Activity of Bactenecin 5
PA Raj, E Marcus, M Edgerton |
Biochemistry | 1996 |
|
New Directions in Antibacterial Research
DT Chu, JJ Plattner, L Katz |
Journal of Medicinal Chemistry | 1996 |
|
Membrane Pores Induced by Magainin
SJ Ludtke, K He, WT Heller, TA Harroun, L Yang, HW Huang |
Biochemistry | 1996 |
|
Antibacterial proteins from porcine polymorphonuclear neutrophils
F Alberdi, MR Alderton, V Korolik, PJ Coloe, SC Smith |
Immunology and Cell Biology | 1995 |
|
Neutrophilic defensins penetrate the blood-brain barrier
H Schluesener, R Meyermann |
Journal of Neuroscience Research | 1995 |
|
A Review of Antimicrobial Peptides: Defensins and Related Cationic Peptides
EW Evans, BG Harmon |
Veterinary Clinical Pathology | 1995 |
|
Cutaneous defenses against dermatophytes and yeasts
DK Wagner, PG Sohnle |
Clinical microbiology reviews | 1995 |
|
Morphology of defensin-treated Staphylococcus aureus
M Shimoda, K Ohki, Y Shimamoto, O Kohashi |
Infection and immunity | 1995 |
|
Effect of a chemical or proteolytic modification on the biological activity of guinea-pig cationic peptide
T Yamashita, S Yomogida, I Nagaoka, K Saito |
Biochimica et Biophysica Acta (BBA) - General Subjects | 1995 |
|
Functional Synergism of the Magainins PGLa and Magainin-2 in Escherichia coli, Tumor Cells and Liposomes
HV Westerhoff, M Zasloff, JL Rosner, RW Hendler, A Waal, AV Gomes, AP Jongsma, A Riethorst, D Juretic |
European Journal of Biochemistry | 1995 |
|
Defensins in granules of phagocytic and non-phagocytic cells
ME Selsted, AJ Ouellette |
Trends in Cell Biology | 1995 |
|
Ribosomally synthesized antimicrobial peptides in prokaryotic and eukaryotic organisms
CM Holz, U Stahl |
Food Biotechnology | 1995 |
|
Immunopharmacology of Respiratory System
C Robinson |
Immunopharmacology of Respiratory System | 1995 |
|
Inheritance of Unequal Numbers of the Genes Encoding the Human Neutrophil Defensins HP-1 and HP-3
WM Mars, P Patmasiriwat, T Maity, V Huff, MM Weil, GF Saunders |
The Journal of biological chemistry | 1995 |
|
Identification of CG-1, a Natural Peptide Antibiotic Derived from Human Neutrophil Cathepsin G
KT Miyasaki, XD Qu, SS Harwig, Y Cho, RI Lehrer |
Advances in dental research | 1995 |
|
Reactive oxygen species in the killing of Pseudomonas aeruginosa by human leukocytes
JP Mizgerd, JD Brain |
Current Microbiology | 1995 |
|
Human CAP18: a novel antimicrobial lipopolysaccharide-binding protein
JW Larrick, M Hirata, RF Balint, J Lee, J Zhong, SC Wright |
Infection and immunity | 1995 |
|
Dynamic reorganization of the alkaline phosphatase-containing compartment during chemotactic peptide stimulation of human neutrophils imaged by backscattered electrons
E Fernndez-Segura, JM Garca, A Campos |
Histochemistry and Cell Biology | 1995 |
|
Cytokines in the treatment of fungal infections
BJ Kullberg, JW Wout |
Biotherapy | 1994 |
|
Growth control of cornea and lens epithelial cells
TW Reid |
Progress in Retinal and Eye Research | 1994 |
|
The in vitro effect of human polymorphonuclear leukocyte azurophil granule components on natural killer cell cytotoxicity
RA Lindemann, A Lala, KT Miyasaki |
Oral Microbiology and Immunology | 1994 |
|
Inhibition of intracellular Histoplasma capsulatum replication by murine macrophages that produce human defensin
MA Couto, L Liu, RI Lehrer, T Ganz |
Infection and immunity | 1994 |
|
Comparison of the sensitivities of Salmonella typhimurium oxyR and katG mutants to killing by human neutrophils
E Papp-Szabò, M Firtel, PD Josephy |
Infection and immunity | 1994 |
|
Killing of Giardia lamblia by cryptdins and cationic neutrophil peptides
SB Aley, M Zimmerman, M Hetsko, ME Selsted, FD Gillin |
Infection and immunity | 1994 |
|
Lactoferricin, a new antimicrobial peptide
EM Jones, A Smart, G Bloomberg, L Burgess, MR Millar |
Journal of Applied Microbiology | 1994 |
|
Localization of human neutrophil peptide (HNP) and its messenger RNA in neutrophil series
Y Date, M Nakazato, K Shiomi, H Toshimori, K Kangawa, H Matsuo, S Matsukura |
Annals of Hematology | 1994 |
|
Bactericidal action of tachyplesin I against oral streptococci
K Masuda, M Ohta, M Ito, S Ohsuka, T Kaneda, N Kato |
Oral Microbiology and Immunology | 1994 |
|
Identification of defensin binding to C1 complement
AV Panyutich, O Szold, PH Poon, Y Tseng, T Ganz |
FEBS Letters | 1994 |
|
Lidocaine Hydrochloride and Acetylsalicylate Kill Bacteria by Disrupting the Bacterial Membrane Potential in Different Ways
S Ohsuka, M Ohta, K Masuda, Y Arakawa, T Kaneda, N Kato |
Microbiology and Immunology | 1994 |
|
Role of Cationic Proteins in the Airway: Hyperresponsiveness Due to Airway Inflammation
AJ Coyle, D Uchida, SJ Ackerman, W Mitzner, CG Irvin |
American journal of respiratory and critical care medicine | 1994 |
|
In vitro activity of naturally occurring peptides (defensins) against Listeria monocytogenes
MG Nascimento, JS Cullor, ME Selsted |
CAD SAUDE PUBLICA | 1994 |
|
Immunology of Infection
JG Sissons, LK Borysiewicz, J Cohen |
Immunology of Infection | 1994 |
|
Cytokines in the Treatment of Infectious Diseases
BJ Kullberg, JW Meer |
1994 | |
|
Localization of human neutrophil peptide (HNP) and its messenger RNA in neutrophil series.
Date Y, Nakazato M, Shiomi K, Toshimori H, Kangawa K, Matsuo H, Matsukura S |
Annals of Hematology | 1994 |
|
Human neutrophil granules and secretory vesicles
N Borregaard, K Lollike, L Kjeldsen, H Sengeløv, L Bastholm, MH Nielsen, DF Bainton |
European Journal of Haematology | 1993 |
|
Defensins are mitogenic for epithelial cells and fibroblasts
CJ Murphy, BA Foster, MJ Mannis, ME Selsted, TW Reid |
Journal of Cellular Physiology | 1993 |
|
Bactenecin, a leukocytic antimicrobial peptide, is cytotoxic to neuronal and glial cells
SW Radermacher, VM Schoop, HJ Schluesener |
Journal of Neuroscience Research | 1993 |
|
Fungicidal properties of defensin NP-1 and activity against Cryptococcus neoformans in vitro
MS Alcouloumre, MA Ghannoum, AS Ibrahim, ME Selsted, JE Edwards |
Antimicrobial agents and chemotherapy | 1993 |
|
Selective inhibition of microbial serine proteases by eNAP-2, an antimicrobial peptide from equine neutrophils
MA Couto, SS Harwig, RI Lehrer |
Infection and immunity | 1993 |
|
Light emission from a Mudlux transcriptional fusion in Salmonella typhimurium is stimulated by hydrogen peroxide and by interaction with the mouse macrophage cell line J774.2
KP Francis, MP Gallagher |
Infection and immunity | 1993 |
|
Defensins promote fusion and lysis of negatively charged membranes
G Fujii, ME Selsted, D Eisenberg |
Protein science : a publication of the Protein Society | 1993 |
|
Leukocytic antimicrobial peptides kill autoimmune T cells
HJ Schluesener, S Radermacher, A Melms, S Jung |
Journal of Neuroimmunology | 1993 |
|
Evidence for homology of buffalo and goat granular cationic peptides
S Sarmah, T More |
Comparative Immunology, Microbiology and Infectious Diseases | 1993 |
|
The effect of biotinylation on the antigenic specificity of anti-defensin monoclonal antibodies
AV Panyutich, EA Baturevich, TS Kolesnikova, T Ganz |
Journal of Immunological Methods | 1993 |
|
Protegrins: leukocyte antimicrobial peptides that combine features of corticostatic defensins and tachyplesins
VN Kokryakov, SS Harwig, EA Panyutich, AA Shevchenko, GM Aleshina, OV Shamova, HA Korneva, RI Lehrer |
FEBS Letters | 1993 |
|
Defensins Reduce the Barrier Integrity of a Cultured Epithelial Monolayer without Cytotoxicity
SD Nygaard, T Ganz, MW Peterson |
American journal of respiratory cell and molecular biology | 1993 |
|
Fungal Infections and Immune Responses
JW Murphy, H Friedman, M Bendinelli |
1993 | |
|
Handbook of Immunochemistry
M Ferenčík |
1993 | |
|
ANCA-Associated Vasculitides
WL Gross |
1993 | |
|
The Activation of Dioxygen and Homogeneous Catalytic Oxidation
DH Barton, AE Martell, DT Sawyer |
1993 | |
|
Antibacterial activity of lactoferrin and a pepsin-derived lactoferrin peptide fragment
K Yamauchi, M Tomita, TJ Giehl, RT rd |
Infection and immunity | 1993 |
|
Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils
ME Selsted, YQ Tang, WL Morris, PA McGuire, MJ Novotny, W Smith, AH Henschen, JS Cullor |
The Journal of biological chemistry | 1993 |
|
Bactericidal activities of lysozyme and aprotinin against Gram-negative and Gram-positive bacteria related to their basic character
A Pellegrini, U Thomas, R Fellenberg, P Wild |
Journal of Applied Microbiology | 1992 |
|
Biochemical mechanisms of intracellular killing of fungi
K Kagaya, K Watanabe, Y Fukazawa, S Suzuki, M Kobayashi, Y Okawa, M Suzuki, H Takahashi, E Brummer, N Kurita, M Miyaji, DA Stevens |
Medical Mycology | 1992 |
|
Agents that increase the permeability of the outer membrane
M Vaara |
Microbiological reviews | 1992 |
|
Identification of eNAP-1, an antimicrobial peptide from equine neutrophils
MA Couto, SS Harwig, JS Cullor, JP Hughes, RI Lehrer |
Infection and immunity | 1992 |
|
Mechanisms of antibacterial action of tachyplesins and polyphemusins, a group of antimicrobial peptides isolated from horseshoe crab hemocytes
M Ohta, H Ito, K Masuda, S Tanaka, Y Arakawa, R Wacharotayankun, N Kato |
Antimicrobial agents and chemotherapy | 1992 |
|
Enteric defensins: antibiotic peptide components of intestinal host defense
ME Selsted, SI Miller, AH Henschen, AJ Ouellette |
The Journal of Cell Biology | 1992 |
|
eNAP-2, a novel cysteine-rich bactericidal peptide from equine leukocytes
MA Couto, SS Harwig, JS Cullor, JP Hughes, RI Lehrer |
Infection and immunity | 1992 |
|
Activity of defensins from human neutrophilic granulocytes against Mycobacterium avium-Mycobacterium intracellulare
K Ogata, BA Linzer, RI Zuberi, T Ganz, RI Lehrer, A Catanzaro |
Infection and immunity | 1992 |
|
Direct inactivation of herpes simplex virus type-2 by rat epidermal protein
M Shimozuma, W Lawrence^Drew, RC Miner, WL Epstein, K Fukuyama |
Antiviral Research | 1992 |
|
The levels and biologic action of the human neutrophil granule peptide HP-1 in lung tumors
A Bateman, A Singh, S Jothy, R Fraser, F Esch, S Solomon |
Peptides | 1992 |
|
Synthesis and characterization of defensin NP-1
AG Rao, T Rood, J Maddox, J Duvick |
International Journal of Peptide and Protein Research | 1992 |
|
Susceptibility of Porphyromonas gingivalis and P. asaccharolytica to the non-oxidative killing mechanisms of human neutrophils
EW Odell, PJ Wu |
Archives of Oral Biology | 1992 |
|
Bactericidal Activities of Rat Defensins and Synthetic Rabbit Defensins on Staphylococci, Klebsiella pneumoniae (Chedid, 277, and 8N3), Pseudomonas aeruginosa (Mucoid and Nonmucoid Strains), Salmonella typhimurium (Ra, Rc, Rd, and Re of LPS Mutants) and E
O Kohashi, T Ono, K Ohki, T Soejima, T Moriya, A Umeda, Y Meno, K Amako, S Funakosi, M Masuda, N Fujii |
Microbiology and Immunology | 1992 |
|
Pharmacology of Second Messengers: A Critical Appraisal
S Garattini |
Drug Metabolism Reviews | 1992 |
|
NMR studies of defensin antimicrobial peptides. 1. Resonance assignment and secondary structure determination of rabbit NP-2 and human HNP-1
XL Zhang, ME Selsted, A Pardi |
Biochemistry | 1992 |
|
NMR studies of defensin antimicrobial peptides. 2. Three-dimensional structures of rabbit NP-2 and human HNP-1
A Pardi, XL Zhang, ME Selsted, JJ Skalicky, PF Yip |
Biochemistry | 1992 |
|
Mononuclear Phagocytes
R van Furth |
1992 | |
|
Mediators of Sepsis
M Lamy, LG Thijs |
1992 | |
|
Microbial Infections
H Friedman, TW Klein, H Yamaguchi |
1992 | |
|
Role of neutrophil-produced myeloperoxidase in the pathogenesis of cataract
MT Yugai, VE Formazyuk, VI Sergienko, AA Ryabtseva, MP Romashova |
Bulletin of Experimental Biology and Medicine | 1992 |
|
Antibacterial activity of cultured human keratinocytes
K Maier, G Ehrhardt, J Frevert |
Archives of Dermatological Research | 1992 |
|
Defensins: ancient but potentially dangerous weapons in the armoury
D Burnett |
Thorax | 1992 |
|
Diagnostische Hämatologie
H Huber, H Löffler, D Pastner |
1992 | |
|
Paneth cells of the human small intestine express an antimicrobial peptide gene
DE Jones, CL Bevins |
The Journal of biological chemistry | 1992 |
|
Effect of defensin HNP-1 of human neutrophils on production of tumor necrosis factor α by human blood monocytes in vitro
NI Misuno, TS Kolesnikova, RI Lehrer, T Ganz, NN Voitenok |
Bulletin of Experimental Biology and Medicine | 1992 |
|
Defensins: microbicidal and cytotoxic peptides of mammalian host defense cells
T Ganz, A Oren, RI Lehrer |
Medical Microbiology and Immunology | 1992 |
|
In vitro killing of oral Capnocytophaga by granule fractions of human neutrophils is associated with cathepsin G activity
KT Miyasaki, AL Bodeau |
Journal of Clinical Investigation | 1991 |
|
Interactions between the antimicrobial peptide, magainin 2, and Salmonella typhimurium lipopolysaccharides
FR Rana, J Blazyk |
FEBS Letters | 1991 |
|
Polycations induce microvascular leakage of macromolecules in hamster cheek pouch
S Rosengren, KE Arfors |
Inflammation | 1991 |
|
Bovine Endometritis: Current and Future Alternative Therapy
AM Hussain, RC Daniel |
Journal of Veterinary Medicine Series A | 1991 |
|
Characterization of cDNA clones encoding guinea pig neutrophil cationic peptides
I Nagaoka, A Someya, K Iwabuchi, T Yamashita |
FEBS Letters | 1991 |
|
Comparison of granule proteins from human polymorphonuclear leukocytes which are bactericidal toward Pseudomonas aeruginosa
KR Wasiluk, KM Skubitz, BH Gray |
Infection and immunity | 1991 |
|
A novel intracellular compartment with unusual secretory properties in human neutrophils
T Kobayashi, JM Robinson |
The Journal of Cell Biology | 1991 |
|
Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa: peptide isolation and cloning of a cDNA
G Diamond, M Zasloff, H Eck, M Brasseur, WL Maloy, CL Bevins |
Proceedings of the National Academy of Sciences | 1991 |
|
Antimicrobial activity of rabbit leukocyte defensins against Treponema pallidum subsp. pallidum
LA Borenstein, ME Selsted, RI Lehrer, JN Miller |
Infection and immunity | 1991 |
|
Differential killing of Actinobacillus actinomycetemcomitans and Capnocytophaga spp. by human neutrophil granule components
KT Miyasaki, AL Bodeau, TF Flemmig |
Infection and immunity | 1991 |
|
Corticostatic peptides cause nifedipine-sensitive volume reduction in jejunal villus enterocytes
RJ MacLeod, JR Hamilton, A Bateman, D Belcourt, J Hu, HP Bennett, S Solomon |
Proceedings of the National Academy of Sciences | 1991 |
|
Complementary DNA sequence of human neutrophil azurocidin, an antibiotic with extensive homology to serine proteases
RP Almeida, M Melchior, D Campanelli, C Nathan, JE Gabay |
Biochemical and Biophysical Research Communications | 1991 |
|
Bactericidal potency and mechanistic specificity of neutrophil defensins against bovine mastitis pathogens
JS Cullor, S Wood, W Smith, L Panico, ME Selsted |
Veterinary Microbiology | 1991 |
|
Human neutrophil peptide defensins induce single strand DNA breaks in target cells
JF Gera, A Lichtenstein |
Cellular Immunology | 1991 |
|
Generation of oxygen radicals in hemocytes of the snail Lymnaea stagnalis in relation to the rate of phagocytosis
CM Adema, EC van Deutekom-Mulder, WP van der Knaap, EA Meuleman, T Sminia |
Developmental & Comparative Immunology | 1991 |
|
An enzyme immunoassay for human defensins
AV Panyutich, NN Voitenok, RI Lehrer, T Ganz |
Journal of Immunological Methods | 1991 |
|
Ultrasensitive assays for endogenous antimicrobial polypeptides
RI Lehrer, M Rosenman, SS Harwig, R Jackson, P Eisenhauer |
Journal of Immunological Methods | 1991 |
|
The effect of HP-1 and related neutrophil granule peptides on DNA synthesis in HL60 cells
A Bateman, A Singh, LF Congote, S Solomon |
Regulatory Peptides | 1991 |
|
A bactericidal protein in Bombina variegata pachypus skin venom
G Mastromei, C Barberio, S Pistolesi, G Delfino |
Toxicon | 1991 |
|
International Review of Cytology
RA Miller |
International Review of Cytology | 1991 |
|
The Function of Lung and Blood Neutrophils in Patients with the Adult Respiratory Distress Syndrome: Implications for the Pathogenesis of Lung Infections
TR Martin, BP Pistorese, LD Hudson, RJ Maunder |
American journal of respiratory and critical care medicine | 1991 |
|
Activated α 2 -Macroglobulin Is a Principal Defensin-binding Protein
A Panyutich, T Ganz |
American journal of respiratory cell and molecular biology | 1991 |
|
H1 Histones Contribute to Candidacidal Activities of Human Epidermal Extract
M Kashima |
The Journal of Dermatology | 1991 |
|
Drugs of Abuse, Immunity, and Immunodeficiency
H Friedman, S Specter, TW Klein |
1991 | |
|
Blood Cell Biochemistry Volume 3
JR Harris |
1991 | |
|
Crystal Structure of Defensin HNP-3, an Amphiphilic Dimer: Mechanisms of Membrane Permeabilization
CP Hill, J Yee, ME Selsted, D Eisenberg |
Science | 1991 |
|
Antimicrobial peptides in the stomach of Xenopus laevis
KS Moore, CL Bevins, MM Brasseur, N Tomassini, K Turner, H Eck, M Zasloff |
The Journal of biological chemistry | 1991 |
|
The isolation and identification of multiple forms of the neutrophil granule peptides from human leukemic cells
A Bateman, A Singh, C Shustik, WM Mars, S Solomon |
The Journal of biological chemistry | 1991 |
|
Bombinin-like peptides with antimicrobial activity from skin secretions of the Asian toad, Bombina orientalis
BW Gibson, DZ Tang, R Mandrell, M Kelly, ER Spindel |
The Journal of biological chemistry | 1991 |
|
Insect immunity. Isolation from a coleopteran insect of a novel inducible antibacterial peptide and of new members of the insect defensin family
P Bulet, S Cociancich, JL Dimarcq, J Lambert, JM Reichhart, D Hoffmann, C Hetru, JA Hoffmann |
The Journal of biological chemistry | 1991 |
|
Polycations induce microvascular leakage of macromolecules in hamster cheek pouch
S Rosengren, |
Inflammation | 1991 |
|
Purification of equine neutrophil lysozyme and its antibacterial activity against gram-positive and gram-negative bacteria.
Pellegrini A, Waiblinger S, Von Fellenberg R |
Veterinary Research Communications | 1991 |
|
Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages
DL Granger, JB Hibbs, JR Perfect, DT Durack |
Journal of Clinical Investigation | 1990 |
|
Azurocidin and a homologous serine protease from neutrophils. Differential antimicrobial and proteolytic properties
D Campanelli, PA Detmers, CF Nathan, JE Gabay |
Journal of Clinical Investigation | 1990 |
|
Immunological aspects of fungal pathogenesis
GS Deepe, WE Bullock |
European Journal of Clinical Microbiology & Infectious Diseases | 1990 |
|
Killing ofCoccidioides immitisby hypochlorous acid or monochloramine
JN Galgiani |
Medical Mycology | 1990 |
|
Defensins
T Ganz, ME Selsted, RI Lehrer |
European Journal of Haematology | 1990 |
|
Leucocytes and pulmonary disorders: Mobilization, activation and role in pathology
A Shock, GJ Laurent |
Molecular Aspects of Medicine | 1990 |
|
In vivo inhibition of tumor growth of B16 melanoma by recombinant interleukin 1β
ME Neville, KM Pezzella, K Schmidt, W Galbraith, N Ackerman |
Cytokine | 1990 |
|
Bacteria-phagocyte interactions: emerging tactics in an ancient rivalry
AS Cross, NM Kelly |
FEMS Microbiology Letters | 1990 |
|
Cloning of cDNA for proteinase 3: a serine protease, antibiotic, and autoantigen from human neutrophils
D Campanelli, M Melchior, Y Fu, M Nakata, H Shuman, C Nathan, JE Gabay |
Journal of Experimental Medicine | 1990 |
|
Rapid membrane permeabilization and inhibition of vital functions of gram-negative bacteria by bactenecins
B Skerlavaj, D Romeo, R Gennaro |
Infection and immunity | 1990 |
|
Insect immunity: expression of the two major inducible antibacterial peptides, defensin and diptericin, in Phormia terranovae
JL Dimarcq, D Zachary, JA Hoffmann, D Hoffmann, JM Reichhart |
The EMBO Journal | 1990 |
|
In vitro sensitivity of oral, gram-negative, facultative bacteria to the bactericidal activity of human neutrophil defensins
KT Miyasaki, AL Bodeau, T Ganz, ME Selsted, RI Lehrer |
Infection and immunity | 1990 |
|
Polymorphic expression of defensins in neutrophils from outbred rats
P Eisenhauer, SS Harwig, D Szklarek, T Ganz, RI Lehrer |
Infection and immunity | 1990 |
|
Ultrastructural localization of proteinase 3, the target antigen of anti-cytoplasmic antibodies circulating in Wegener's granulomatosis
E Csernok, J Lüdemann, WL Gross, DF Bainton |
The American Journal of Pathology | 1990 |
|
Bactenecins, defense polypeptides of bovine neutrophils, are generated from precursor molecules stored in the large granules
M Zanetti, L Litteri, R Gennaro, H Horstmann, D Romeo |
The Journal of Cell Biology | 1990 |
|
Effects of antiretroviral dideoxynucleosides on polymorphonuclear leukocyte function
E Roilides, D Venzon, PA Pizzo, M Rubin |
Antimicrobial agents and chemotherapy | 1990 |
|
Characterization of defensin resistance phenotypes associated with mutations in the phoP virulence regulon of Salmonella typhimurium
SI Miller, WS Pulkkinen, ME Selsted, JJ Mekalanos |
Infection and immunity | 1990 |
|
Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes
BL Kagan, ME Selsted, T Ganz, RI Lehrer |
Proceedings of the National Academy of Sciences | 1990 |
|
Granulins, a novel class of peptide from leukocytes
A Bateman, D Belcourt, H Bennett, C Lazure, S Solomon |
Biochemical and Biophysical Research Communications | 1990 |
|
Salmonella virulence: new clues to intramacrophage survival
EA Groisman, MH Saier |
Trends in Biochemical Sciences | 1990 |
|
Killing of oral, gram-negative, facultative bacteria by the rabbit defensin, NP-1
KT Miyasaki, AL Bodeau, ME Selsted, T Ganz, RI Lehrer |
Oral Microbiology and Immunology | 1990 |
|
3 Neutrophil function tests
AP Haynes, J Fletcher |
Baillière's Clinical Haematology | 1990 |
|
Amino acid sequence of CAP37, a human neutrophil granule-derived antibacterial and monocyte-specific chemotactic glycoprotein structurally similar to neutrophil elastase
J Pohl, HA Pereira, NM Martin, JK Spitznagel |
FEBS Letters | 1990 |
|
The Bacteria
DW Frank, SE West, BH Iglewski |
The Bacteria | 1990 |
|
Molecular Basis of Bacterial Pathogenesis
JM Tennent, S Hultgren, BI Marklund, K Forsman, M Göransson, BE Uhlin, S Normark |
Molecular Basis of Bacterial Pathogenesis | 1990 |
|
Humoral Immunity in Insects
PE Dunn |
BioScience | 1990 |
|
Structural Relationship Between Human Salivary Histatins
RF Troxler, GD Offner, T Xu, JC Vanderspek, FG Oppenheim |
Journal of dental research | 1990 |
|
Endotoxin
H Friedman, TW Klein, M Nakano, A Nowotny |
1990 | |
|
Amino acid sequences of two proline-rich bactenecins. Antimicrobial peptides of bovine neutrophils
RW Frank, R Gennaro, K Schneider, M Przybylski, D Romeo |
The Journal of biological chemistry | 1990 |
|
A potent antibacterial protein in royal jelly. Purification and determination of the primary structure of royalisin
S Fujiwara, J Imai, M Fujiwara, T Yaeshima, T Kawashima, K Kobayashi |
The Journal of biological chemistry | 1990 |
|
A novel mouse gene family coding for cationic, cysteine-rich peptides. Regulation in small intestine and cells of myeloid origin
AJ Ouellette, JC Lualdi |
The Journal of biological chemistry | 1990 |
|
Isolation of two isoforms of a novel 15-kDa protein from rabbit polymorphonuclear leukocytes that modulate the antibacterial actions of other leukocyte proteins
CE Ooi, J Weiss, O Levy, P Elsbach |
The Journal of biological chemistry | 1990 |
|
Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity
RI Lehrer, A Barton, KA Daher, SS Harwig, T Ganz, ME Selsted |
Journal of Clinical Investigation | 1989 |
|
Human neutrophil gelatinase is a component of specific granules
MS Hibbs, DF Bainton |
Journal of Clinical Investigation | 1989 |
|
Monocyte-chemotactic activity of defensins from human neutrophils
MC Territo, T Ganz, ME Selsted, R Lehrer |
Journal of Clinical Investigation | 1989 |
|
Leukocytic Oxygen Activation and Microbicidal Oxidative Toxin
JK Hurst, WC Barrette |
Critical Reviews in Biochemistry and Molecular Biology | 1989 |
|
Current concepts in Cryptococcosis
TF Patterson, VT Andriole |
European Journal of Clinical Microbiology & Infectious Diseases | 1989 |
|
Experimental Basis for the Clinical Epidemiology of Fungal Infections. A Review: Die experimentelle Grundlage der Minischen Epidemiologie von Pilzinfektionen. Übersicht
A Schaffner |
Mycoses | 1989 |
|
Strategies for the Development of Vaccines for Typhoid Fever, Shigellosis, and Cholera
SI Miller, JJ Mekalanos |
Annals of the New York Academy of Sciences | 1989 |
|
The opsonizing ligand on Salmonella typhimurium influences incorporation of specific, but not azurophil, granule constituents into neutrophil phagosomes
KA Joiner, T Ganz, J Albert, D Rotrosen |
The Journal of Cell Biology | 1989 |
|
Purification and antimicrobial properties of three defensins from rat neutrophils
PB Eisenhauer, SS Harwig, D Szklarek, T Ganz, ME Selsted, RI Lehrer |
Infection and immunity | 1989 |
|
Antibiotic proteins of human polymorphonuclear leukocytes
JE Gabay, RW Scott, D Campanelli, J Griffith, C Wilde, MN Marra, M Seeger, CF Nathan |
Proceedings of the National Academy of Sciences | 1989 |
|
Interactions of Neisseria gonorrhoeae with human neutrophils
RF Rest, WM Shafer |
Clinical microbiology reviews | 1989 |
|
Enhancing effect of serum ultrafiltrate on the activity of cephalosporins against gram-negative bacilli
JE Leggett, WA Craig |
Antimicrobial agents and chemotherapy | 1989 |
|
Antibacterial activity of human natural killer cells
P Garcia-Peñarrubia, FT Koster, RO Kelley, TD McDowell, AD Bankhurst |
Journal of Experimental Medicine | 1989 |
|
Insect immunity: isolation from immune blood of the dipteran Phormia terranovae of two insect antibacterial peptides with sequence homology to rabbit lung macrophage bactericidal peptides
J Lambert, E Keppi, JL Dimarcq, C Wicker, JM Reichhart, B Dunbar, P Lepage, AV Dorsselaer, J Hoffmann, J Fothergill |
Proceedings of the National Academy of Sciences | 1989 |
|
Candidacidal activities of proteins partially purified from rat epidermis
M Kashima, H Takahashi, M Shimozuma, WL Epstein, K Fukuyama |
Infection and immunity | 1989 |
|
Purification, composition, and activity of two bactenecins, antibacterial peptides of bovine neutrophils
R Gennaro, B Skerlavaj, D Romeo |
Infection and immunity | 1989 |
|
Developmental regulation of cryptdin, a corticostatin/defensin precursor mRNA in mouse small intestinal crypt epithelium
AJ Ouellette, RM Greco, M James, D Frederick, J Naftilan, JT Fallon |
The Journal of Cell Biology | 1989 |
|
A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence
SI Miller, AM Kukral, JJ Mekalanos |
Proceedings of the National Academy of Sciences | 1989 |
|
Purification, primary structure, and biological activity of guinea pig neutrophil cationic peptides
T Yamashita, K Saito |
Infection and immunity | 1989 |
|
Quantitation of a cationic antimicrobial granule protein of human polymorphonuclear leukocytes by ELISA
HA Pereira, LE Martin, JK Spitznagel |
Journal of Immunological Methods | 1989 |
|
Involvement of Reactive Oxygen Metabolites in the Candidacidal Activity of Human Neutrophils Stimulated by Muramyl Dipeptide or Tumor Necrosis Factor
C Jupin, M Parant, L Chedid |
Immunobiology | 1989 |
|
Neutrophil dysfunction after thermal injury: alteration of phagolysosomal acidification in patients with large burns
R Bjerknes, H Vindenes |
Burns | 1989 |
|
Roles of the Neutrophil and Other Mediators in Adult Respiratory Distress Syndrome
DW Swank, SB Moore |
Mayo Clinic Proceedings | 1989 |
|
Determination of the three-dimensional solution structure of the antihypertensive and antiviral protein BDS-I from the sea anemone Anemonia sulcata: a study using nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing
PC Driscoll, AM Gronenborn, L Beress, GM Clore |
Biochemistry | 1989 |
|
General mechanism for the bacterial toxicity of hypochlorous acid: abolition of ATP production
WC Barrette, DM Hannum, WD Wheeler, JK Hurst |
Biochemistry | 1989 |
|
Modulation of functional activity of human polymorphonuclear and mononuclear phagocytes by intravenous gamma globulin
W Pruzanski, S Saito |
Inflammation | 1989 |
|
Infections and Athritis
JJ Calabro, WC Dick |
1989 | |
|
Functions of the Natural Immune System
CW Reynolds, RH Wiltrout |
1989 | |
|
Pathology Reviews · 1989
E Rubin, I Damjanov |
1989 | |
|
A Salmonella Locus that Controls Resistance to Microbicidal Proteins from Phagocytic Cells
PI Fields, EA Groisman, F Heffron |
Science | 1989 |
|
Purification and Characterization of Human Neutrophil Peptide 4, a Novel Member of the Defensin Family
CG Wilde, JE Griffith, MN Marra, JL Snable, RW Scott |
The Journal of biological chemistry | 1989 |
|
Determination of the disulfide array in the human defensin HNP-2
ME Selsted, SS Harwig |
The Journal of biological chemistry | 1989 |
|
Specific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages
DL Granger, JB Hibbs, JR Perfect, DT Durack |
Journal of Clinical Investigation | 1988 |
|
Modulation of the in vitro candidacidal activity of human neutrophil defensins by target cell metabolism and divalent cations
RI Lehrer, T Ganz, D Szklarek, ME Selsted |
Journal of Clinical Investigation | 1988 |
|
Microbicidal/cytotoxic proteins of neutrophils are deficient in two disorders: Chediak-Higashi syndrome and "specific" granule deficiency
T Ganz, JA Metcalf, JI Gallin, LA Boxer, RI Lehrer |
Journal of Clinical Investigation | 1988 |
|
NEUTROPHIL DEATH AS A DEFENCE MECHANISM AGAINST CANDIDA ALBICANS INFECTIONS
MP Mcnamara, C Collins-Lech, JH Wiessner, BL Hahn, PG Sohnle |
The Lancet | 1988 |
|
The human neutrophil. Function and dysfunction
N Borregaard |
European Journal of Haematology | 1988 |
|
Characteristics of Dermal Invasion in Experimental Cutaneous Candidiasis Leucopenic Mice
BL Hahn, PG Sohnle |
Journal of Investigative Dermatology | 1988 |
|
Interaction of macrophage cationic proteins with the outer membrane of Pseudomonas aeruginosa
JG Sawyer, NL Martin, RE Hancock |
Infection and immunity | 1988 |
|
Cerebrospinal fluid macrophage response to experimental cryptococcal meningitis: relationship between in vivo and in vitro measurements of cytotoxicity
JR Perfect, MM Hobbs, DL Granger, DT Durack |
Infection and immunity | 1988 |
|
Isolation of a complementary DNA clone encoding a precursor to human eosinophil major basic protein
M McGrogan, C Simonsen, R Scott, J Griffith, N Ellis, J Kennedy, D Campanelli, C Nathan, J Gabay |
Journal of Experimental Medicine | 1988 |
|
Effect of small cationic leukocyte peptides (defensins) on the permeability barrier of the outer membrane
P Viljanen, P Koski, M Vaara |
Infection and immunity | 1988 |
|
Antimicrobial mechanisms against Acinetobacter calcoaceticus of rat polymorphonuclear leukocyte granule extract
MJ Loeffelholz, MC Modrzakowski |
Infection and immunity | 1988 |
|
Small, antibacterial and large, inactive peptides of neutrophil granules share immunoreactivity to a monoclonal antibody
R Marzari, B Scaggiante, B Skerlavaj, M Bittolo, R Gennaro, D Romeo |
Infection and immunity | 1988 |
|
Isolation and characterization of human defensin cDNA clones
KA Daher, RI Lehrer, T Ganz, M Kronenberg |
Proceedings of the National Academy of Sciences | 1988 |
|
Killing of Proteus mirabilis by polymorphonuclear leukocyte granule proteins: evidence for species specificity by antimicrobial proteins
WM Shafer, SA Engle, LE Martin, JK Spitznagel |
Infection and immunity | 1988 |
|
Synergistic cytolysis mediated by hydrogen peroxide combined with peptide defensins
AK Lichtenstein, T Ganz, ME Selsted, RI Lehrer |
Cellular Immunology | 1988 |
|
Inhibition of protein kinase C by defensins, antibiotic peptides from human neutrophils
PA Charp, WG Rice, RL Raynor, E Reimund, JM Kinkade, T Ganz, ME Selsted, RI Lehrer, JF Kuo |
Biochemical Pharmacology | 1988 |
|
Solution structures of the rabbit neutrophil defensin NP-5
A Pardi, DR Hare, ME Selsted, RD Morrison, DA Bassolino, AC Bach |
Journal of Molecular Biology | 1988 |
|
Isolation and characterization of two new low-molecular-weight protein proteinase inhibitors from the granule-rich fraction of equine neutrophilic granulocytes
A Pellegrini, G Hägeli, R Fellenberg |
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology | 1988 |
|
Neutrophil Granule Constituents and Their Release in Health and Disease
LA Boxer, JE Smolen |
Hematology/Oncology Clinics of North America | 1988 |
|
Oxygen-Independent Bactericidal Systems: Mechanisms and Disorders
R Lehrer, T Ganz, ME Selsted |
Hematology/Oncology Clinics of North America | 1988 |
|
Host Defenses and Immunomodulation to Intracellular Pathogens
TK Eisenstein, WE Bullock, N Hanna |
1988 | |
|
The Respiratory Burst and Its Physiological Significance
AJ Sbarra, RR Strauss |
1988 | |
|
Influence of cationic superoxide generation enhancing protein (SGEP) on phagocytic and intracellular bactericidal activity of human polymorphonuclear cells
W Pruzanski, S Saito, M Alam, NS Ranadive |
Inflammation | 1988 |
|
Phagocytes and Disease
MS Klempner, B Styrt, J Ho |
1988 | |
|
Bacteria, Complement and the Phagocytic Cell
FC Cabello, C Pruzzo |
1988 | |
|
Immunopathogenetic Mechanisms of Arthritis
JA Goodacre, WC Dick |
1988 | |
|
Characterization of two crystal forms of human defensin neutrophil cationic peptide 1, a naturally occurring antimicrobial peptide of leukocytes
RL Stanfield, EM Westbrook, ME Selsted |
The Journal of biological chemistry | 1988 |
|
Structure and bactericidal activity of an antibiotic dodecapeptide purified from bovine neutrophils
D Romeo, B Skerlavaj, M Bolognesi, R Gennaro |
The Journal of biological chemistry | 1988 |
|
Purification, primary structure, and antimicrobial activities of a guinea pig neutrophil defensin
ME Selsted, SS Harwig |
Infection and immunity | 1987 |
|
Nonoxidative microbicidal activity in normal human alveolar and peritoneal macrophages
JR Catterall, CM Black, JP Leventhal, NW Rizk, JS Wachtel, JS Remington |
Infection and immunity | 1987 |
|
Defensins mediate the microbicidal activity of human neutrophil granule extract against Acinetobacter calcoaceticus
GI Greenwald, T Ganz |
Infection and immunity | 1987 |
|
Role of high-avidity binding of human neutrophil myeloperoxidase in the killing of Actinobacillus actinomycetemcomitans
KT Miyasaki, JJ Zambon, CA Jones, ME Wilson |
Infection and immunity | 1987 |
|
Extracellular release of antimicrobial defensins by human polymorphonuclear leukocytes
T Ganz |
Infection and immunity | 1987 |
|
Nonoxidative antimicrobial effects of human polymorphonuclear leukocyte granule proteins on Chlamydia spp. in vitro
KB Register, CH Davis, PB Wyrick, WM Shafer, JK Spitznagel |
Infection and immunity | 1987 |
|
Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor
M Zasloff |
Proceedings of the National Academy of Sciences | 1987 |
|
Relationship between antibody-dependent tumour cell lysis and primary granule exocytosis by human neutrophils
F Dallegri, G Frumento, A Ballestrero, R Goretti, F Patrone |
Clinical & Experimental Immunology | 1987 |
|
Neutrophil function disorders
LA Boxer, ML Morganroth |
Disease-a-Month | 1987 |
|
Neutrophils in Human Diseases
HL Malech, JI Gallin |
New England Journal of Medicine | 1987 |
|
Late intraphagosomal hydrogen ion concentration favors the in vitro antimicrobial capacity of a 37-kilodalton cationic granule protein of human neutrophil granulocytes
WM Shafer, LE Martin, JK Spitznagel |
Infection and immunity | 1986 |
|
Oxidative and nonoxidative killing of Actinobacillus actinomycetemcomitans by human neutrophils
KT Miyasaki, ME Wilson, AJ Brunetti, RJ Genco |
Infection and immunity | 1986 |
|
Subcellular location and properties of bactericidal factors from human neutrophils
JE Gabay, JM Heiple, ZA Cohn, CF Nathan |
Journal of Experimental Medicine | 1986 |
|
Synergistic activity of rabbit granulocyte peptides against Candida albicans
RI Lehrer, D Szklarek, T Ganz, ME Selsted |
Infection and immunity | 1986 |
|
Direct inactivation of viruses by human granulocyte defensins
KA Daher, ME Selsted, RI Lehrer |
Journal of virology | 1986 |
|
Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques
E Jucker |
1986 | |
|
Stimulated human neutrophils limit iron-catalyzed hydroxyl radical formation as detected by spin-trapping techniques
BE Britigan, GM Rosen, BY Thompson, Y Chai, MS Cohen |
The Journal of biological chemistry | 1986 |
|
Genetic Engineering
P Little |
Genetic Engineering | 1981 |
|
Correlation between natural and antibody-dependent cell-mediated cytotoxicity against tumor targets in the mouse. II. Characterization of the effector cells
ED Carlo, G Forni, P Lollini, MP Colombo, A Modesti, P Musiani |
JNCI Journal of the National Cancer Institute | 1979 |
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