Modification of low density lipoproteins by human arterial smooth muscle cells was characterized by increased electrophoretic mobility and increased content of malondialdehyde-like oxidation products reactive with thiobarbituric acid. Lipoprotein modification was promoted by micromolar concentrations of iron or copper in the culture medium and was metal ion concentration- and time-dependent. The ability of diverse media to promote smooth muscle cell-mediated low density lipoprotein modification correlated with their iron concentration. Therefore, metal ion concentration of culture media contributes substantially to low density lipoprotein modification in vitro. Human monocyte-derived macrophages took up and esterified the cholesterol from modified low density lipoprotein more extensively than from native low density lipoprotein. Metal ion-mediated modification of low density lipoprotein may be a contributing factor to the pathogenesis of arteriosclerosis.
J W Heinecke, H Rosen, A Chait
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Mineral Intake and Cardiovascular Disease, Cancer, and All-Cause Mortality: Findings from the Golestan Cohort Study.
Yazdanpanah MH, Sharafkhah M, Poustchi H, Etemadi A, Sheikh M, Kamangar F, Pourshams A, Boffetta P, Dawsey SM, Abnet CC, Malekzadeh R, Hashemian M |
Nutrients | 2024 |
Serum Zinc and Copper Concentrations and Dyslipidemia as Risk Factors of Cardiovascular Disease in Adults: Data Mining Techniques.
Mansoori A, Ghiasi Hafezi S, Ansari A, Arab Yousefabadi S, Kolahi Ahari R, Darroudi S, Eshaghnezhad M, Ferns G, Ghayour-Mobarhan M, Esmaily H, Effati S |
Biological trace element research | 2024 |
Association of Blood Trace Elements Levels with Cardiovascular Disease in US Adults: a Cross-Sectional Study from the National Health and Nutrition Examination Survey 2011-2016.
Guo Q, Cai J, Qu Q, Cheang I, Shi J, Pang H, Li X |
Biological Trace Element Research | 2023 |
Redox and metal profiles in human coronary endothelial and smooth muscle cells under hyperoxia, physiological normoxia and hypoxia: Effects of NRF2 signaling on intracellular zinc
Smith MJ, Yang F, Griffiths A, Morrell A, Chapple SJ, Siow RC, Stewart T, Maret W, Mann GE |
Redox Biology | 2023 |
Effect of Vitamin E on Apoptosis of the Endothelial Cells of the Carotid Arteries in Hypercholesterolemic Male Rabbits
Jafar Haeri SM, Dashti G, Mardani M, Rashidi B, Nikgoftar Fathi A, al-sadat Haeri N |
ARYA Atherosclerosis | 2023 |
Dietary copper intake and risk of myocardial infarction in US adults: A propensity score-matched analysis.
Wen H, Niu X, Hu L, Sun N, Zhao R, Wang Q, Li Y |
Frontiers in Cardiovascular Medicine | 2022 |
Circulating Serum Copper Is Associated with Atherosclerotic Cardiovascular Disease, but Not Venous Thromboembolism: A Prospective Cohort Study.
Kunutsor SK, Dey RS, Laukkanen JA |
Pulse (Basel, Switzerland) | 2021 |
Lipoproteins in Atherosclerosis Process
V Arnao, A Tuttolomondo, M Daidone, A Pinto |
Current medicinal chemistry | 2019 |
Oxylipin profile of human low-density lipoprotein is dependent on its extent of oxidation
A Surendran, H Zhang, T Winter, A Edel, H Aukema, A Ravandi |
Atherosclerosis | 2019 |
Associations between copper and zinc intakes from diet and mortality from cardiovascular disease in a large population-based prospective cohort study
ES Eshak, H Iso, K Yamagishi, K Maruyama, M Umesawa, A Tamakoshi |
The Journal of Nutritional Biochemistry | 2018 |
Effect of manufacturing temperature and storage duration on stability of chemically defined media measured with LC-MS/MS: Impact of manufacturing and storage on CDM components measured with LC-MS/MS
F Krattenmacher, T Heermann, A Calvet, B Krawczyk, T Noll |
Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986) | 2018 |
Serum Zn/Cu Ratio Is Associated with Renal Function, Glycemic Control, and Metabolic Parameters in Japanese Patients with and without Type 2 Diabetes: A Cross-sectional Study
H Hamasaki, Y Kawashima, H Yanai |
Frontiers in Endocrinology | 2016 |
Oxidative theory of atherosclerosis and antioxidants
R Salvayre, A Negre-Salvayre, C Camaré |
Biochimie | 2016 |
Association of chemical constituents and pollution sources of ambient fine particulate air pollution and biomarkers of oxidative stress associated with atherosclerosis: A panel study among young adults in Beijing, China
S Wu, D Yang, H Wei, B Wang, J Huang, H Li, M Shima, F Deng, X Guo |
Chemosphere | 2015 |
Detecting LDL-oxidation process using Langmuir monolayer technique
Z Khattari |
Measurement | 2015 |
Preventive Nutrition: The Comprehensive Guide for Health Professionals
A Bendich, RJ Deckelbaum |
2015 | |
Atherogenesis and iron: from epidemiology to cellular level
F Vinchi, MU Muckenthaler, MC da Silva, GÃ Balla, JÃ Balla, VÃ Jeney |
Frontiers in pharmacology | 2014 |
Studies in Diabetes
I Obrosova, MJ Stevens, MA Yorek |
2014 | |
The role of oxidized low-density lipoproteins in atherosclerosis: the myths and the facts
G Maiolino, G Rossitto, P Caielli, V Bisogni, GP Rossi, LA Calò |
Mediators of Inflammation | 2013 |
Atherosclerosis Induced by Chlamydophila pneumoniae : A Controversial Theory
H Honarmand |
Interdisciplinary Perspectives on Infectious Diseases | 2013 |
Advanced Bioactive Compounds Countering the Effects of Radiological, Chemical and Biological Agents
GN Pierce, VI Mizin, A Omelchenko |
2013 | |
Intravenous ferric chloride hexahydrate supplementation induced endothelial dysfunction and increased cardiovascular risk among hemodialysis patients
KL Kuo, SC Hung, YP Lin, CF Tang, TS Lee, CP Lin, DC Tarng |
PloS one | 2012 |
Myeloperoxidase targets apolipoprotein A-I, the major high density lipoprotein protein, for site-specific oxidation in human atherosclerotic lesions
B Shao, S Pennathur, JW Heinecke |
The Journal of biological chemistry | 2012 |
Methods in Enzymology
JD Stone, AS Chervin, DH Aggen, DM Kranz |
Protein Engineering for Therapeutics Part B | 2012 |
Long-Term Consequences of Iron-Fortified Flour Consumption in Nonanemic Men
H Pouraram, I Elmadfa, AR Dorosty, M Abtahi, TR Neyestani, S Sadeghian |
Annals of Nutrition and Metabolism | 2012 |
Haimovici's Vascular Surgery: Ascher/Haimovici's Vascular Surgery
B Liu, KC Kent |
Haimovici's Vascular Surgery: Ascher/Haimovici's Vascular Surgery | 2012 |
Intravenous Ferric Chloride Hexahydrate Supplementation Induced Endothelial Dysfunction and Increased Cardiovascular Risk among Hemodialysis Patients
KL Kuo, SC Hung, YP Lin, CF Tang, TS Lee, CP Lin, DC Tarng, T Thum |
PloS one | 2012 |
Homogeneous Catalysis with Metal Complexes
G Duca |
2012 | |
Minerals and Lipids Profiles in Cardiovascular Disorders in South Asia
NB Rizvi, SA Nagra |
2012 | |
The Relationship Between Serum Levels of Zn and Cu and Severity of Coronary Atherosclerosis
Y Islamoglu, O Evliyaoglu, E Tekbas, H Cil, MA Elbey, Z Atilgan, H Kaya, Z Bilik, A Akyuz, S Alan |
Biological Trace Element Research | 2011 |
Effect of atorvastatin therapy on oxidant-antioxidant status and atherosclerotic plaque formation
ED Sezer, EY Sozmen, D Nart, T Onat |
Vascular Health and Risk Management | 2011 |
Primary human monocyte differentiation regulated by Nigella sativa pressed oil
MC Mat, AS Mohamed, SS Hamid |
Lipids in Health and Disease | 2011 |
Peroxidation of lipoproteins in multiple sclerosis
G Ferretti, T Bacchetti |
Journal of the Neurological Sciences | 2011 |
The Inhibitory Effects of Fucoidans from Laminaria japonica on Oxidation of Human Low-Density Lipoproteins
X Zhao, JF Wang, CH Xue |
Advanced Materials Research | 2011 |
Methylenetetrahydrofolate reductase C677T gene polymorphism in turkish patients with polycystic ovary syndrome
M Karadeniz, M Erdogan, A Zengi, Z Eroglu, S Tamsel, M Olukman, F Saygili, C Yilmaz |
Endocrine | 2010 |
Metabolism and atherogenic disease association of lysophosphatidylcholine
G Schmitz, K Ruebsaamen |
Atherosclerosis | 2010 |
Involvement of HNP-1 in different oxidation mechanisms in human endothelial cells
D Fen, P Lingyan, H Chunyan, Y Hong, C Jia, W Junzhu |
European Journal of Lipid Science and Technology | 2010 |
Mechanisms of LDL oxidation
H Yoshida, R Kisugi |
Clinica Chimica Acta | 2010 |
Mapping oxidations of apolipoprotein B-100 in human low-density lipoprotein by liquid chromatography–tandem mass spectrometry
S Chakraborty, Y Cai, MA Tarr |
Analytical Biochemistry | 2010 |
Studies on Cardiovascular Disorders
H Sauer, AM Shah, FR Laurindo |
2010 | |
The effect of toluene on oxidative processes in rat blood
SS S., SB Z., G Gadjanski-Omerovic |
Journal of the Serbian Chemical Society | 2009 |
The biological relevance and measurement of plasma markers of oxidative stress in diabetes and cardiovascular disease
JW Stephens, MP Khanolkar, SC Bain |
Atherosclerosis | 2009 |
Endothelin-1 activates ETA receptors on human vascular smooth muscle cells to yield proteoglycans with increased binding to LDL
ML Ballinger, ME Ivey, N Osman, WG Thomas, PJ Little |
Atherosclerosis | 2009 |
Lysophosphatidylcholine increases C-type natriuretic peptide expression in human vascular smooth muscle cells via membrane distortion
MC Mendonça, A Rezende, SQ Doi, DF Sellitti |
Vascular Pharmacology | 2009 |
The Alga Dunaliella
L Oppen-Bezalel, A Shaish |
The Alga Dunaliella | 2009 |
Free Radicals and Antioxidant Protocols
RM Uppu, SN Murthy, WA Pryor, NL Parinandi |
2009 | |
Free Radicals and Antioxidant Protocols
RM Uppu, SN Murthy, WA Pryor, NL Parinandi |
2009 | |
Free Radicals and Antioxidant Protocols
RM Uppu, SN Murthy, WA Pryor, NL Parinandi |
2009 | |
Free Radicals and Antioxidant Protocols
RM Uppu, SN Murthy, WA Pryor, NL Parinandi |
2009 | |
Free Radicals and Antioxidant Protocols
RM Uppu, SN Murthy, WA Pryor, NL Parinandi |
2009 | |
Free Radicals and Antioxidant Protocols
RM Uppu, SN Murthy, WA Pryor, NL Parinandi |
2009 | |
Preventive Nutrition
A Bendich, RJ Deckelbaum |
2009 | |
Can Iron Chelators Influence the Progression of Atherosclerosis?
JJ Marx, AE Kartikasari, NA Georgiou |
Hemoglobin | 2008 |
Distribution of selected elements in atherosclerotic plaques of apoE/LDLR-double knockout mice assessed by synchrotron radiation-induced micro-XRF spectrometry
M Gajda, K Banaś, A Banaś, J Jawień, Ł Mateuszuk, S Chłopicki, WM Kwiatek, T Cichocki, G Falkenberg |
X-Ray Spectrometry | 2008 |
A novel method for production of lipid hydroperoxide- or oxysterol-rich low-density lipoprotein
AB Gerry, L Satchell, DS Leake |
Atherosclerosis | 2008 |
Serum Bilirubin and Ferritin Levels Link Heme Oxygenase-1 Gene Promoter Polymorphism and Susceptibility to Coronary Artery Disease in Diabetic Patients
YH Chen, LY Chau, JW Chen, SJ Lin |
Diabetes care | 2008 |
Analysis of modified apolipoprotein B-100 structures formed in oxidized low-density lipoprotein using LC-MS/MS
T Obama, R Kato, Y Masuda, K Takahashi, T Aiuchi, H Itabe |
PROTEOMICS | 2007 |
Ascochlorin suppresses oxLDL-induced MMP-9 expression by inhibiting the MEK/ERK signaling pathway in human THP-1 macrophages
JH Kang, JK Kim, WH Park, KK Park, TS Lee, J Magae, H Nakajima, CH Kim, YC Chang |
Journal of Cellular Biochemistry | 2007 |
Low-density lipoprotein is oxidized by phospholipase A2 and lipoxygenase in xanthoma lesions
H Nakajima, M Ikeda, Y Hirata, M Matsumoto, M Seike, H Kodama |
European Journal of Lipid Science and Technology | 2007 |
Mechanisms for Oxidative Stress in Diabetic Cardiovascular Disease
S Pennathur, JW Heinecke |
Antioxidants & Redox Signaling | 2007 |
Effect of 5- O -Methylhirsutanonol on Nuclear Factor-κB-Dependent Production of NO and Expression of iNOS in Lipopolysaccharide-Induced RAW264.7 Cells
JM Han, WS Lee, JR Kim, J Son, OH Kwon, HJ Lee, JJ Lee, TS Jeong |
Journal of Agricultural and Food Chemistry | 2007 |
Effect of Albizia julibrissin Water Extracts on Low-Density Lipoprotein Oxidization
K Vaughn, C McClain, DJ Carrier, S Wallace, J King, S Nagarajan, E Clausen |
Journal of Agricultural and Food Chemistry | 2007 |
Lipoprotein oxidation in cardiovascular disease: chief culprit or innocent bystander?
JW Heinecke |
Journal of Experimental Medicine | 2006 |
Low-density lipoproteins are more electronegatively charged in type 1 than in type 2 diabetes mellitus
R Gambino, E Pisu, G Pagano, M Cassader |
Lipids | 2006 |
The interaction between oxidative stress and biomarkers of inflammation in atherosclerosis
VD B., T Cvetkovic, M Deljanin-Ilic, V Cosic, L Zvezdanovic, S Kundalic, S Madic, I Stojanovic |
Jugoslovenska medicinska biohemija | 2006 |
Proteome analysis of human monocytic THP-1 cells primed with oxidized low-density lipoproteins
JH Kang, HT Kim, MS Choi, WH Lee, TL Huh, YB Park, BJ Moon, OS Kwon |
PROTEOMICS | 2006 |
Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions
N Stanley, N Stadler, AA Woods, PG Bannon, MJ Davies |
Free radical biology & medicine | 2006 |
Oxidized low density lipoprotein suppresses lipopolysaccharide-induced inflammatory responses in microglia: Oxidative stress acts through control of inflammation
OS Kim, CS Lee, E Joe, I Jou |
Biochemical and Biophysical Research Communications | 2006 |
Lipoprotein oxidation in cardiovascular disease: chief culprit or innocent bystander?
JW Heinecke |
Journal of Experimental Medicine | 2006 |
Antioxidant Activities of Abietane Diterpenoids Isolated from Torreya nucifera Leaves
WS Lee, JR Kim, JM Han, KC Jang, DE Sok, TS Jeong |
Journal of Agricultural and Food Chemistry | 2006 |
Essential Roles of Lipoxygenases in LDL Oxidation and Development of Atherosclerosis
Y Takahashi, H Zhu, T Yoshimoto |
Antioxidants & Redox Signaling | 2005 |
Chronic depletion of glutathione (GSH) and minimal modification of LDL in vivo: its prevention by glutathione mono ester (GME) therapy
NS Rajasekaran, S Sathyanarayanan, NS Devaraj, H Devaraj |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2005 |
Copper- and magnesium protoporphyrin complexes inhibit oxidative modification of LDL induced by hemin, transition metal ions and tyrosyl radicals
S Kapiotis, M Hermann, M Exner, H Laggner, BM Gmeiner |
Free Radical Research | 2005 |
Group V Secretory Phospholipase A 2 -modified Low Density Lipoprotein Promotes Foam Cell Formation by a SR-A- and CD36-independent Process That Involves Cellular Proteoglycans
BB Boyanovsky, DR van der Westhuyzen, NR Webb |
The Journal of biological chemistry | 2005 |
Iron, Lipids, and Risk of Cancer in the Framingham Offspring Cohort
AG Mainous, BJ Wells, RJ Koopman, CJ Everett, JM Gill |
American Journal of Epidemiology | 2005 |
Functional foods, cardiovascular disease and diabetes
E Herrera, PF Dodds |
Functional foods, cardiovascular disease and diabetes | 2004 |
In vivo oxidizability of LDL in type 2 diabetic patients in good and poor glycemic control
R Gambino, B Uberti, N Alemanno, E Pisu, G Pagano, M Cassader |
Atherosclerosis | 2004 |
Novel 3,5-diaryl pyrazolines and pyrazole as low-density lipoprotein (LDL) oxidation inhibitor
TS Jeong, KS Kim, JR Kim, KH Cho, S Lee, WS Lee |
Bioorganic & Medicinal Chemistry Letters | 2004 |
Demethylbellidifolin preserves endothelial function by reduction of the endogenous nitric oxide synthase inhibitor level
DJ Jiang, JL Jiang, HQ Zhu, GS Tan, SQ Liu, KP Xu, YJ Li |
Journal of Ethnopharmacology | 2004 |
Evaluation of some biochemical changes in diabetic patients
MA Abou-Seif, AA Youssef |
Clinica Chimica Acta | 2004 |
Oxidized low-density lipoproteins may induce expression of monocyte chemotactic protein-3 in atherosclerotic plaques
MK Jang, JY Kim, NH Jeoung, MA Kang, MS Choi, GT Oh, KT Nam, WH Lee, YB Park |
Biochemical and Biophysical Research Communications | 2004 |
Effects of silencing leukocyte-type 12/15-lipoxygenase using short interfering RNAs
SL Li, RS Dwarakanath, Q Cai, L Lanting, R Natarajan |
Journal of lipid research | 2004 |
Thematic review series: The Pathogenesis of Atherosclerosis The oxidation hypothesis of atherogenesis: the role of oxidized phospholipids and HDL
M Navab, GM Ananthramaiah, ST Reddy, BJ van Lenten, BJ Ansell, GC Fonarow, K Vahabzadeh, S Hama, G Hough, N Kamranpour, JA Berliner, AJ Lusis, AM Fogelman |
Journal of lipid research | 2004 |
Mechanisms by which cysteine can inhibit or promote the oxidation of low density lipoprotein by copper
RA Patterson, DJ Lamb, DS Leake |
Atherosclerosis | 2003 |
A novel method of following oxidation of low-density lipoprotein using a sensitive fluorescent probe, diphenyl-1-pyrenylphosphine
Y Okimoto, E Warabi, Y Wada, E Niki, T Kodama, N Noguchi |
Free radical biology & medicine | 2003 |
Plasma iron is associated with lipid peroxidation in an elderly population
C Lasheras, S González, JM Huerta, S Braga, ÁM Patterson, S Fernández |
Journal of Trace Elements in Medicine and Biology | 2003 |
Trace elemental distributions in induced atherosclerotic lesions using nuclear microscopy
R Minqin, F Watt, BT Huat, B Halliwell |
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms | 2003 |
Clinical trials of vitamin E in coronary artery disease: is it time to reconsider the low-density lipoprotein oxidation hypothesis?
Jay W Heinecke |
Current Atherosclerosis Reports | 2003 |
Proteomic approach to coronary atherosclerosis shows ferritin light chain as a significant marker: evidence consistent with iron hypothesis in atherosclerosis
SA You, SR Archacki, G Angheloiu, CS Moravec, S Rao, M Kinter, EJ Topol, Q Wang |
Physiological genomics | 2003 |
Iron status in association with cardiovascular disease risk in 3 controlled feeding studies
JL Derstine, LE Murray-Kolb, S Yu-Poth, RL Hargrove, PM Kris-Etherton, JL Beard |
The American journal of clinical nutrition | 2003 |
Homocysteine Levels and C677T Polymorphism of Methylenetetrahydrofolate Reductase in Women with Polycystic Ovary Syndrome
F Orio, S Palomba, SD Biase, A Colao, L Tauchmanova, S Savastano, D Labella, T Russo, F Zullo, G Lombardi |
The Journal of clinical endocrinology and metabolism | 2003 |
Immunhistochemischer Nachweis ver�nderter Low-density-Lipoproteine (ox-LDL) in der Gef��wand bei Patienten mit Arteriitis temporalis
SC Beutelspacher, N Serbecic, F Tamaddon, M Mehrabi, HE Voelcker |
Der Ophthalmologe | 2003 |
Wine
A Klatsky |
Wine | 2002 |
Vitamin E Inhibits Lysophosphatidylcholine-Induced Endothelial Dysfunction and Platelet Activation
T Murohara, H Ikeda, A Katoh, Y Takajo, Y Otsuka, N Haramaki, T Imaizumi |
Antioxidants & Redox Signaling | 2002 |
Effect of prolonged incubation with copper on endothelium-dependent relaxation in rat isolated aorta
A Chiarugi, GM Pitari, R Costa, M Ferrante, L Villari, M Amico-Roxas, T Godfraind, A Bianchi, S Salomone |
British Journal of Pharmacology | 2002 |
Inverse relationship between total testosterone and anti-oxidized low density lipoprotein antibody levels in ageing males
W Barud, R Palusiński, J Bełtowski, G Wójcicka |
Atherosclerosis | 2002 |
Role of oxidized low-density lipoprotein in renal disease
P Heeringa, JW Tervaert |
Current Opinion in Nephrology and Hypertension | 2002 |
Effect of dietary copper supplementation on cell composition and apoptosis in atherosclerotic lesions of cholesterol-fed rabbits
DJ Lamb, TY Avades, MD Allen, K Anwar, GE Kass, GA Ferns |
Atherosclerosis | 2002 |
Beneficial effects of blood donation on high density lipoprotein concentration and the oxidative potential of low density lipoprotein
H Jaarsveld, GF Pool |
Atherosclerosis | 2002 |
Increased reactive oxygen species production with antisense oligonucleotides directed against uncoupling protein 2 in murine endothelial cells
C Duval, A Nègre-Salvayre, A Doglio, R Salvayre, L Pénicaud, L Casteilla |
Biochemistry and Cell Biology | 2002 |
Low density lipoprotein oxidized in xanthoma tissue induces the formation and infiltration of foam cells
Y Hirata, K Okawa, M Ikeda, M Seike, M Matsumoto, H Kodama |
Journal of Dermatological Science | 2002 |
Macrophages, Oxidation, and Endometriosis
N Santanam, AA Murphy, S Parthasarathy |
Annals of the New York Academy of Sciences | 2002 |
Wine Flavonoids Protect against LDL Oxidation and Atherosclerosis
M Aviram, B Fuhrman |
Annals of the New York Academy of Sciences | 2002 |
Oxidized amino acids: culprits in human atherosclerosis and indicators of oxidative stress1,2 1This article is part of a series of reviews on “Oxidatively Modified Proteins in Aging and Disease.” The full list of papers may be found on the homepage of the journal. 2Guest Editor: Earl Stadtman
JW Heinecke |
Free radical biology & medicine | 2002 |
Helicobacter pylori masks differences in homocysteine plasma levels between controls and type 2 diabetic patients
S Cenerelli, P Bonazzi, R Galeazzi, I Testa, AR Bonfigli, C Sirolla, S Giunta, L Galeazzi, D Fumelli, R Testa |
European Journal of Clinical Investigation | 2002 |
Macrophages take up triacylglycerol-rich emulsions at a faster rate upon co-incubation with native and modified LDL: An investigation on the role of natural chylomicrons in atherosclerosis
MD Carvalho, LM Harada, M Gidlund, DF Ketelhuth, P Boschcov, EC Quint�o |
Journal of Cellular Biochemistry | 2002 |
Assay methods of modified lipoproteins in plasma
Y Yamaguchi, M Kunitomo, J Haginaka |
Journal of Chromatography B | 2002 |
Advances in Cell Aging and Gerontology
T Fülöp, K Hirokawa, G Dupuis, A Larbi, G Pawelec |
Advances in Cell Aging and Gerontology | 2002 |
Comparative time-courses of copper-ion-mediated protein and lipid oxidation in low-density lipoprotein
HM Knott, A Baoutina, MJ Davies, RT Dean |
Archives of Biochemistry and Biophysics | 2002 |
Homocysteine promotes the LDL oxidase activity of ceruloplasmin
M Exner, M Hermann, R Hofbauer, B Hartmann, S Kapiotis, B Gmeiner |
FEBS Letters | 2002 |
Impact of body iron status on myocardial perfusion, left ventricular function, and angiographic morphologic features in patients with hypercholesterolemia
AE Say, M Gursurer, MV Yazicioglu, B Ersek |
American Heart Journal | 2002 |
Modulation of inflammatory mediators and pparγand nfκb expression by pravastatin in response to lipoproteins in human monocytes in vitro
I Zelvyte, R Dominaitiene, M Crisby, S Janciauskiene |
Pharmacological Research | 2002 |
Receptor mediated yolk protein uptake in the crabScylla serrata: crustacean vitellogenin receptor recognizes related mammalian serum lipoproteins
S Warrier, T Subramoniam |
Molecular Reproduction and Development | 2002 |
Rapid isolation of VLDL subfractions: assessment of composition and susceptibility to copper-mediated oxidation
J McEneny, C McMaster, ER Trimble, IS Young |
Journal of lipid research | 2002 |
Pathophysiology and Maternal Biologic Markers of Preeclampsia
J Masse, Y Giguere, A Kharfi, J Girouard, JC Forest |
Endocrine | 2002 |
Iron overload diminishes atherosclerosis in apolipoprotein e-deficient mice
Elizabeth A. Kirk, Jay W. Heinecke, and Renee C. LeBoeuf |
Journal of Clinical Investigation | 2001 |
Oxidized low-density lipoprotein promotes mature dendritic cell transition from differentiating monocyte
L Perrin-Cocon, F Coutant, S Agaugué, S Deforges, P André, V Lotteau |
Journal of immunology (Baltimore, Md. : 1950) | 2001 |
Handbook of Antioxidants
K Meissner, W Siems, O Sommerburg, M Leichsenring |
Handbook of Antioxidants | 2001 |
Characterization of peroxynitrite-oxidized low density lipoprotein binding to human CD36
RA Guy, GF Maguire, I Crandall, PW Connelly, KC Kain |
Atherosclerosis | 2001 |
The role of vitamin E in atherogenesis: linking the chemical, biological and clinical aspects of the disease
J Neuzil, C Weber, A Kontush |
Atherosclerosis | 2001 |
The Interaction between Copper and Coronary Risk Indicators
B Adam, S Aslan, A Bedir, M Alvur |
Japanese Heart Journal | 2001 |
Oxidation of LDL enhances the cholesteryl ester transfer protein (CETP)-mediated cholesteryl ester transfer rate to HDL, bringing on a diminished net transfer of cholesteryl ester from HDL to oxidized LDL
LN Castilho, HC Oliveira, PM Cazita, AC de Oliveira, A Sesso, EC Quintão |
Clinica Chimica Acta | 2001 |
No influence of hemochromatosis-related gene mutations on restenosis rate in a retrospective study of 137 patients after coronary stent implantation
M Ferrari, GS Werner, J Rieber, BM Richartz, HH Sigusch, A Brandstädt, H Mudra, HR Figulla |
Acute Cardiac Care | 2001 |
Flavonoids protect LDL from oxidation and attenuate atherosclerosis
B Fuhrman, M Aviram |
Current Opinion in Lipidology | 2001 |
Role of oxidized low-density lipoprotein in the atherosclerosis of uremia
TB Drüeke, TN Khoa, ZA Massy, V Witko-Sarsat, B Lacour, B Descamps-Latscha |
Kidney International | 2001 |
Inhibition of Oxidized Low-density Lipoprotein-induced Apoptosis in Endothelial Cells by Nitric Oxide: PEROXYL RADICAL SCAVENGING AS AN ANTIAPOPTOTIC MECHANISM
S Kotamraju, N Hogg, J Joseph, LK Keefer, B Kalyanaraman |
The Journal of biological chemistry | 2001 |
Correlation between total homocysteine, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol in the serum of patients with myocardial infarction
D Qujeq, TS Omran, L Hosini |
Clinical Biochemistry | 2001 |
A Protective Role for Kidney Apolipoprotein E: REGULATION OF MESANGIAL CELL PROLIFERATION AND MATRIX EXPANSION
G Chen, L Paka, Y Kako, P Singhal, W Duan, S Pillarisetti |
The Journal of biological chemistry | 2001 |
Is the Emperor Wearing Clothes?: Clinical Trials of Vitamin E and the LDL Oxidation Hypothesis
JW Heinecke |
Arteriosclerosis, thrombosis, and vascular biology | 2001 |
Oxidized-LDL Enhances Coronary Vasoconstriction by Increasing the Activity of Protein Kinase C Isoforms α and ε
JB Giardina, DJ Tanner, RA Khalil |
Hypertension | 2001 |
Diabetes and Cardiovascular Disease
A Angel, N Dhalla, G Pierce, P Singal |
2001 | |
Immunohistochemical evidence for the myeloperoxidase/H2O2/halide system in human atherosclerotic lesions: colocalization of myeloperoxidase and hypochlorite-modified proteins
A Daugherty, JL Dunn, DL Rateri, JW Heinecke |
Journal of Clinical Investigation | 2000 |
Lipoproteins modify the macrophage uptake of triacylglycerol emulsion and of zymosan particles by similar mechanisms
MD Carvalho, VE Tobias, CM Vendrame, AF Shimabukuro, M Gidlund, EC Quintão |
Lipids | 2000 |
Elevated plasma homocysteine concentrations after pediatric heart transplantations
F Parisi, S Kost-Byerly, I Saponara, R Donato, G Liso |
Transplant International | 2000 |
Vitamin E supplementation increases the resistance of both LDL and HDL to oxidation and increases cholesteryl ester transfer activity
S Arrol, MI Mackness, PN Durrington |
Atherosclerosis | 2000 |
Oxidized low-density lipoprotein is localized in the ventricles of hearts from patients with coronary heart disease
C Ekmekcioglu, MR Mehrabi, HD Glogar, M Jucewicz, I Volf, PG Spieckermann |
International Journal of Clinical & Laboratory Research | 2000 |
NOVEL CELL CULTURE MEDIUM FOR USE IN OXIDATION EXPERIMENTS PROVIDES INSIGHTS INTO MECHANISMS OF ENDOTHELIAL CELL–MEDIATED OXIDATION OF LDL
TR Dugas, DW Morel, EH Harrison |
In Vitro Cellular & Developmental Biology - Animal | 2000 |
Novel cell culture medium for use in oxidation experiments provides insights into mechanisms of endothelial cell-mediated oxidation of LDL
TR Dugas, DW Morel, EH Harrison |
In Vitro Cellular & Developmental Biology - Animal | 2000 |
Ceruloplasmin and cardiovascular disease
PL Fox, B Mazumder, E Ehrenwald, CK Mukhopadhyay |
Free radical biology & medicine | 2000 |
Bioactive products of phospholipid oxidation: isolation, identification, measurement and activities
G Subbanagounder, AD Watson, JA Berliner |
Free radical biology & medicine | 2000 |
The oxidative modification hypothesis of atherogenesis: an overview
GM Chisolm, D Steinberg |
Free radical biology & medicine | 2000 |
Regulation of cell growth by oxidized LDL
GM Chisolm, YC Chai |
Free radical biology & medicine | 2000 |
Elevated levels of protein-bound p-hydroxyphenylacetaldehyde, an amino-acid-derived aldehyde generated by myeloperoxidase, are present in human fatty streaks, intermediate lesions and advanced atherosclerotic lesions
SL Hazen, JP Gaut, JR Crowley, FF Hsu, JW Heinecke |
Biochemical Journal | 2000 |
Immunohistochemical evidence for the myeloperoxidase/H2O2/halide system in human atherosclerotic lesions: colocalization of myeloperoxidase and hypochlorite-modified proteins
A Daugherty, JL Dunn, DL Rateri, JW Heinecke |
European Journal of Biochemistry | 2000 |
p -Hydroxyphenylacetaldehyde, an Aldehyde Generated by Myeloperoxidase, Modifies Phospholipid Amino Groups of Low Density Lipoprotein in Human Atherosclerotic Intima
JI Heller, JR Crowley, SL Hazen, DM Salvay, P Wagner, S Pennathur, JW Heinecke |
The Journal of biological chemistry | 2000 |
Oxidized LDL–Induced NF-κB Activation and Subsequent Expression of Proinflammatory Genes Are Defective in Monocyte-Derived Macrophages From CD36-Deficient Patients
M Janabi, S Yamashita, K Hirano, N Sakai, H Hiraoka, K Matsumoto, Z Zhang, S Nozaki, Y Matsuzawa |
Arteriosclerosis, thrombosis, and vascular biology | 2000 |
Textbook of Angiology
JB Chang |
2000 | |
Oxidative Stress and Vascular Disease
JF Keaney |
2000 | |
Age-related Increases in Plasma Phosphatidylcholine Hydroperoxide Concentrations in Control Subjects and Patients with Hyperlipidemia
M Kinoshita, S Oikawa, K Hayasaka, A Sekikawa, T Nagashima, T Toyota, T Miyazawa |
Clinical chemistry | 2000 |
Mechanisms of Action of Intravenous Immunoglobulin (IVIG)
MD Kazatchkine, B Bellon, SV Kaveri |
Multiple sclerosis (Houndmills, Basingstoke, England) | 2000 |
Age-related decrease of dehydroepiandrosterone concentrations in low density lipoproteins and its role in the susceptibility of low density lipoproteins to lipid peroxidation
A Khalil, JP Fortin, JG LeHoux, T Fülöp |
Journal of lipid research | 2000 |
The effect of fenofibrate treatment on endothelium-dependent relaxation induced by oxidative modified low density lipoprotein from hyperlipidemic patients
B Liang, J C McMaster, E A Kroeger, G M Hatch, D Mymin, T Dembinski, G Arthur, G Shen, R Y Man, P C Choy |
Molecular and Cellular Biochemistry | 2000 |
Novel cell culture medium for use in oxidation experiments provides insights into mechanisms of endothelial cell-mediated oxidation of LDL
TR Dugas, DW Morel, EH Harrison |
In vitro cellular & developmental biology. Animal | 2000 |
Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E–deficient mice
T Cyrus, JL Witztum, DJ Rader, R Tangirala, S Fazio, MF Linton, CD Funk |
Journal of Clinical Investigation | 1999 |
Is lipid peroxidation relevant to atherogenesis?
JW Heinecke |
Journal of Clinical Investigation | 1999 |
Low-Density Lipoprotein Oxidation and Its Prevention by Amidothionophosphate Antioxidants
O Tirosh, J Katzhendler, Y Barenholz, R Kohen |
Antioxidants & Redox Signaling | 1999 |
Homocysteine, a risk factor for cardiovascular disease
K Prasad |
International Journal of Angiology | 1999 |
Biochemical evidence for a link between elevated levels of homocysteine and lipid peroxidation in vivo
JW Heinecke |
Current Atherosclerosis Reports | 1999 |
Keishi-bukuryo-gan prevents the progression of atherosclerosis in cholesterol-fed rabbit
N Sekiya, N Tanaka, T Itoh, Y Shimada, H Goto, K Terasawa |
Phytotherapy Research | 1999 |
Essential involvement of 12-lipoxygenase in regiospecific andstereospecific oxidation of low density lipoprotein by macrophages
T Sakashita, Y Takahashi, T Kinoshita, T Yoshimoto |
European Journal of Biochemistry | 1999 |
Molecular biology and gene transfer in atherosclerosis in the stenting era
NM Caplice, RD Simari, DR Holmes |
Acute Cardiac Care | 1999 |
Oxidized Low-Density Lipoprotein Induces Macrophage Respiratory Burst via Its Protein Moiety: A Novel Pathway in Atherogenesis?
T Nguyen-Khoa, ZA Massy, V Witko-Sarsat, S Canteloup, M Kebede, B Lacour, T Drüeke, B Descamps-Latscha |
Biochemical and Biophysical Research Communications | 1999 |
Different apolipoprotein B breakdown patterns in models of oxidized low density lipoprotein
H Viita, O Närvänen, S Ylä-Herttuala |
Life Sciences | 1999 |
Regulation of Ferritin Light Chain Gene Expression by Oxidized Low-Density Lipoproteins in Human Monocytic THP-1 Cells
MK Jang, MS Choi, YB Park |
Biochemical and Biophysical Research Communications | 1999 |
Antioxidant Food Supplements in Human Health
A Gozin, H Sellak, E Franzini, C Pasquier |
Antioxidant Food Supplements in Human Health | 1999 |
Nitrogen dioxide radical generated by the myeloperoxidase-hydrogen peroxide-nitrite system promotes lipid peroxidation of low density lipoprotein
J Byun, DM Mueller, JS Fabjan, JW Heinecke |
FEBS Letters | 1999 |
Does serum ferritin correlate with coronary angiography findings?
WC Manfroi, AJ Zago, PR Caramori, R Cruz, J Oliveira, LS Kirschnick, K Ordovás, RH Candiago, J Souza, LW Ribeiro, C Leitão, ML Brizolara |
International Journal of Cardiology | 1999 |
Effects of atrial and brain natriuretic peptides on lysophosphatidylcholine-mediated endothelial dysfunction
T Murohara, K Kugiyama, Y Ota, H Doi, N Ogata, M Ohgushi, H Yasue |
Journal of Cardiovascular Pharmacology | 1999 |
Reactions of · NO, · NO 2 and peroxynitrite in membranes: Physiological implications
SP Goss, RJ Singh, N Hogg, B Kalyanaraman |
Free Radical Research | 1999 |
The Oxidation of Lipoproteins by Monocytes-Macrophages: BIOCHEMICAL AND BIOLOGICAL MECHANISMS
GM Chisolm, SL Hazen, PL Fox, MK Cathcart |
The Journal of biological chemistry | 1999 |
Lack of a relationship between serum ferritin levels and coronary atherosclerosis evaluated by coronary arteriography
WC Manfroi, AJ Zago, R Cruz, J Oliveira, LS Kirschnick, K Ordovás, RH Candiago, J Souza, LW Ribeiro, C Leitão, ML Brizolara |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] | 1999 |
Mass spectrometric quantification of amino acid oxidation products in proteins: insights into pathways that promote LDL oxidation in the human artery wall
JW Heinecke |
The FASEB Journal | 1999 |
Dietary β-Carotene and α-Tocopherol Combination Does Not Inhibit Atherogenesis in an ApoE–Deficient Mouse Model
A Shaish, J George, B Gilburd, P Keren, H Levkovitz, D Harats |
Arteriosclerosis, thrombosis, and vascular biology | 1999 |
Iron-Deficient Diet Reduces Atherosclerotic Lesions in ApoE-Deficient Mice
TS Lee, MS Shiao, CC Pan, LY Chau |
Circulation | 1999 |
CD36, a Novel Receptor for Oxidized Low-Density Lipoproteins, Is Highly Expressed on Lipid-Laden Macrophages in Human Atherosclerotic Aorta
A Nakata, Y Nakagawa, M Nishida, S Nozaki, J Miyagawa, T Nakagawa, R Tamura, K Matsumoto, K Kameda-Takemura, S Yamashita, Y Matsuzawa |
Arteriosclerosis, thrombosis, and vascular biology | 1999 |
Leukocytes Utilize Myeloperoxidase-Generated Nitrating Intermediates as Physiological Catalysts for the Generation of Biologically Active Oxidized Lipids and Sterols in Serum
D Schmitt, Z Shen, R Zhang, SM Colles, W Wu, RG Salomon, Y Chen, GM Chisolm, SL Hazen |
Biochemistry | 1999 |
Lipolysis-induced iron release from diferric transferrin: possible role of lipoprotein lipase in LDL oxidation
C Balagopalakrishna, L Paka, S Pillarisetti, IJ Goldberg |
Journal of lipid research | 1999 |
Iron and LDL-oxidation in atherogenesis
XM Yuan, UT Brunk |
APMIS | 1998 |
Vitamin E Protects Human Aortic Endothelial Cells from Cytotoxic Injury Induced by Oxidized LDL In Vitro 11This project has been funded at least in part with Federal funds from the U.S. Department of Agriculture, Agricultural Research Service under contract number 53-K06-01. The contents of this publication do not necessarily reflect the views or policies of the U.S. Department of Agriculture, nor does mention of trade names, commercial products, or organizations imply endorsement by the U.S. government
A Martin, D Wu, SN Meydani, JB Blumberg, M Meydani |
The Journal of Nutritional Biochemistry | 1998 |
Antioxidant protection of LDL by physiologic concentrations of estrogens is specific for 17-beta-estradiol
GT Shwaery, JA Vita, JF Keaney |
Atherosclerosis | 1998 |
Oxidation resistance of LDL is correlated with vitamin E status in β-thalassemia intermedia
L Tesoriere, D D'Arpa, A Maggio, V Giaccone, E Pedone, MA Livrea |
Atherosclerosis | 1998 |
Inhibitory Effects of Lipid Oxidation on the Activity of Plasma Lecithin-Cholesterol Acyltransferase
S KAMIYAMA, T YAMATO, Y FURUKAWA |
Bioscience, Biotechnology, and Biochemistry | 1998 |
Strong increase in hydroxy fatty acids derived from linoleic acid in human low density lipoproteins of atherosclerotic patients
W Jira |
Chemistry and Physics of Lipids | 1998 |
Oxidized Low-Density Lipoprotein, a Two-Faced Janus in Coronary Artery Disease?
S Parthasarathy |
Biochemical Pharmacology | 1998 |
Novel 21-aminosteroid U-74389G inhibits low-density lipoprotein peroxidation induced by .OH and O2−. free radicals
A Khalil, A Fortun, S Hébert, JP Jay-Gerin, AE Abbouyi, J Wallach, T Fülöp |
Life Sciences | 1998 |
Oxidized Lipids as Inflammatory Agonists
AM Fogelman |
Journal of Vascular and Interventional Radiology | 1998 |
Involvement of endotoxins or tumor necrosis factor-α in macrophage-mediated oxidation of low density lipoprotein
K Fujiwara, H Sato, S Bannai |
FEBS Letters | 1998 |
Oxidants and antioxidants in the pathogenesis of atherosclerosis: implications for the oxidized low density lipoprotein hypothesis
JW Heinecke |
Atherosclerosis | 1998 |
Aggressive medical therapy for the prevention and treatment of coronary artery disease
MJ Malloy, JP Kane |
Disease-a-Month | 1998 |
Copper-dependent Inflammation and Nuclear Factor- κ B Activation by Particulate Air Pollution
T Kennedy, AJ Ghio, W Reed, J Samet, J Zagorski, J Quay, J Carter, L Dailey, JR Hoidal, RB Devlin |
American journal of respiratory cell and molecular biology | 1998 |
Ceruloplasmin Copper Induces Oxidant Damage by a Redox Process Utilizing Cell-Derived Superoxide as Reductant †
CK Mukhopadhyay, PL Fox |
Biochemistry | 1998 |
Strong synergistic anti-peroxidative effects of HDL3 and ascorbic acid against copper-catalyzed LDL peroxidation
M Yoshikawa, N Sakuma, T Hibino, N Tamai, K Sasai, T Yoshimata, Y Jin-no, Y Kamiya |
Biochimica et Biophysica Acta | 1998 |
Cell-mediated oxidation of LDL: Comparison of different cell types of the atherosclerotic lesion
K Müller, KL Carpenter, MJ Mitchinson |
Free Radical Research | 1998 |
A Simple Method for Assessing Copper-Mediated Oxidation of Very-Low-Density Lipoprotein Isolated by Rapid Ultracentrifugation
J McEneny, ER Trimble, IS Young |
Annals of Clinical Biochemistry | 1998 |
Synthesis, Isolation, and Characterization of the Adduct Formed in the Reaction of p -Hydroxyphenyl- acetaldehyde with the Amino Headgroup of Phosphatidylethanolamine and Phosphatidylserine
SL Hazen, J Heller, FF Hsu, A d'Avignon, JW Heinecke |
Chemical Research in Toxicology | 1998 |
LDL oxidation by activated monocytes: characterization of the oxidized LDL and requirement for transition metal ions
X Xing, J Baffic, CP Sparrow |
Journal of lipid research | 1998 |
Cholesterol and oxygenated cholesterol concentrations are markedly elevated in peripheral tissue but not in brain from mice with the Niemann-Pick type C phenotype
GS Tint, P Pentchev, G Xu, AK Batta, S Shefer, G Salen, A Honda |
Journal of Inherited Metabolic Disease | 1998 |
Radical-induced lipoprotein and plasma lipid oxidation in normal and apolipoprotein E gene knockout (apoE–/–) mice: apoE–/– mouse as a model for testing the role of tocopherol-mediated peroxidation in atherogenesis
J Neužil, JK Christison, E Iheanacho, JC Fragonas, V Zammit, NH Hunt, R Stocker |
Journal of lipid research | 1998 |
Subendothelial retention of lipoprotein (a). Evidence that reduced heparan sulfate promotes lipoprotein binding to subendothelial matrix
S Pillarisetti, L Paka, JC Obunike, L Berglund, IJ Goldberg |
Journal of Clinical Investigation | 1997 |
Localization of distinct F2-isoprostanes in human atherosclerotic lesions
D Praticò, L Iuliano, A Mauriello, L Spagnoli, JA Lawson, J Rokach, J Maclouf, F Violi, GA FitzGerald |
Journal of Clinical Investigation | 1997 |
The possible role of copper ions in atherogenesis: the Blue Janus
GA Ferns, DJ Lamb, A Taylor |
Atherosclerosis | 1997 |
Oxidized low density lipoproteins stimulate eicosanoid synthesis in mesangial cells
K Matoba, M Ozaki, Y Yamada, M Mune, S Yukawa |
Clinical and Experimental Nephrology | 1997 |
The Role of Oxidized LDL in Atherogenesis: Immunological Response and Anti-phospholipid Antibodies
JL Witztum, S Hörkkö |
Annals of the New York Academy of Sciences | 1997 |
Oxidized LDLs But Not Native LDLs Augment Ba2+ Currents Through L-Type Ca2+ Channels of the A7r5 Smooth Muscle-Derived Cell Line
Y Mio, S Suga, T Osanai, T Kanazawa, K Onodera, J Wada, N Kamimura, M Wakui |
Cellular Signalling | 1997 |
Dynamics of oxidation of LDL and its inhibition by antioxidants
E Niki, N Noguchi |
BioFactors | 1997 |
ESTROGENS AND ATHEROSCLEROSIS
LN and, G Chaudhuri |
Annual Review of Pharmacology and Toxicology | 1997 |
Attenuation of diet-induced atherosclerosis in rabbits with a highly selective 15-lipoxygenase inhibitor lacking significant antioxidant properties
SM Sendobry, JA Cornicelli, K Welch, T Bocan, B Tait, BK Trivedi, N Colbry, RD Dyer, SJ Feinmark, A Daugherty |
British Journal of Pharmacology | 1997 |
Increased Uptake of LDL by Oxidized Macrophages is the Result of an Initial Enhanced LDL Receptor Activity and of a Further Progressive Oxidation of LDL
B Fuhrman, O Judith, S Keidar, L Ben-Yaish, M Kaplan, M Aviram |
Free radical biology & medicine | 1997 |
The Role of Copper Reduction by α-Tocopherol in Low-Density Lipoprotein Oxidation
JM Proudfoot, KD Croft, IB Puddey, LJ Beilin |
Free radical biology & medicine | 1997 |
Antioxidant Constituents from Licorice Roots: Isolation, Structure Elucidation and Antioxidative Capacity Toward LDL Oxidation
J Vaya, PA Belinky, M Aviram |
Free radical biology & medicine | 1997 |
Effect of lipoproteins on cultured human mesangial cells
Y Nishida, N Yorioka, H Oda, M Yamakido |
American Journal of Kidney Diseases | 1997 |
Mass Spectrometric Quantification of Markers for Protein Oxidation by Tyrosyl Radical, Copper, and Hydroxyl Radical in Low Density Lipoprotein Isolated from Human Atherosclerotic Plaques
C Leeuwenburgh, JE Rasmussen, FF Hsu, DM Mueller, S Pennathur, JW Heinecke |
The Journal of biological chemistry | 1997 |
Does an acidic pH explain why low density lipoprotein is oxidised in atherosclerotic lesions?
DS Leake |
Atherosclerosis | 1997 |
Both Intracellular and Extracellular Vitamin C Inhibit Atherogenic Modification of LDL by Human Vascular Endothelial Cells
A Martin, B Frei |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
Plasma LDL Oxidation Leads to Its Aggregation in the Atherosclerotic Apolipoprotein E-Deficient Mice
I Maor, T Hayek, R Coleman, M Aviram |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
Exogenous Oxidized Low-Density Lipoprotein Injures and Alters the Barrier Function of Endothelium in Rats In Vivo
S Rangaswamy, MS Penn, GM Saidel, GM Chisolm |
Circulation research | 1997 |
Copper Ions Promote Peroxidation of Low Density Lipoprotein Lipid by Binding to Histidine Residues of Apolipoprotein B100, But They Are Reduced at Other Sites on LDL
P Wagner, JW Heinecke |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
Antioxidant Protection of LDL by Physiological Concentrations of 17β-Estradiol: Requirement for Estradiol Modification
GT Shwaery, JA Vita, JF Keaney |
Circulation | 1997 |
Genistein, the Dietary-Derived Angiogenesis Inhibitor, Prevents LDL Oxidation and Protects Endothelial Cells From Damage by Atherogenic LDL
S Kapiotis, M Hermann, I Held, C Seelos, H Ehringer, BM Gmeiner |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
Effect of Iron Overload and Iron Deficiency on Atherosclerosis in the Hypercholesterolemic Rabbit
AJ Dabbagh, GT Shwaery, JF Keaney, B Frei |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
Body Iron Stores and the Risk of Carotid Atherosclerosis: Prospective Results From the Bruneck Study
S Kiechl, J Willeit, G Egger, W Poewe, F Oberhollenzer |
Circulation | 1997 |
Oxidative modification of low density lipoprotein in normal and hyperlipidemic patients: effect of lysophosphatidylcholine composition on vascular relaxation
L Chen, B Liang, DE Froese, S Liu, JT Wong, K Tran, GM Hatch, D Mymin, EA Kroeger, RY Man, PC Choy |
Journal of lipid research | 1997 |
Mechanisms of enhanced macrophage apoE secretion by oxidized LDL
AA Cader, FM Steinberg, T Mazzone, A Chait |
Journal of lipid research | 1997 |
Oxidative modifications of low-density lipoproteins (LDL) by the human endothelial cell line EA.hy 926
MA Pech-Amsellem, I Myara, I Pico, C Mazière, JC Mazière, N Moatti |
Experientia | 1996 |
Oxidation of Low-Density Lipoprotein by Human Monocyte-Macrophages Results in Toxicity to the Oxidising Culture
CE Marchant, CV der Wen, NS Law, SJ Hardwick, KL Carpenter, MJ Mitchinson |
Free Radical Research | 1996 |
Iron in human atheroma and LDL oxidation by macrophages following erythrophagocytosis
XM Yuan, W Li, AG Olsson, UT Brunk |
Atherosclerosis | 1996 |
Catechol based inhibitors of 15-lipoxygenase
BD Tait, RD Dyer, BJ Auerbach, D Bornemeier, L Guilds-Zamarka, M Oxender, BD Roth, BK Trivedi, JA Cornicelli |
Bioorganic & Medicinal Chemistry Letters | 1996 |
The role of oxidized lipoproteins in atherogenesis
JA Berliner, JW Heinecke |
Free radical biology & medicine | 1996 |
In vitro antioxidant effects of estrogens with a hindered 3-OH function on the copper-induced oxidation of low density lipoprotein
CP Miller, I Jirkovsky, DA Hayhurst, SJ Adelman |
Steroids | 1996 |
Advances in Lipobiology
PJ Trotter, DR Voelker |
Advances in Lipobiology | 1996 |
Bilirubin sensitized photooxidation of human plasma low density lipoprotein
SA Hulea, TL Smith, E Wasowicz, K Fred |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1996 |
Ascorbate promotes low density lipoprotein oxidation in the presence of ferritin
L Dai, PG Winyard, Z Zhang, DR Blake, CJ Morris |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1996 |
Autoantibody titers to oxidized low-density lipoprotein in patients with coronary atherosclerosis
MN Bui, MN Sack, G Moutsatsos, DY Lu, P Katz, R McCown, JA Breall, CE Rackley |
American Heart Journal | 1996 |
Lipid and lipoprotein oxidation: basic mechanisms and unresolved questions in vivo
R Bucala |
Redox Report | 1996 |
Macrophage erythrophagocytosis and iron exocytosis
XM Yuan, AG Olsson, UT Brunk |
Redox Report | 1996 |
Erratum: Human (THP-1) Macrophages Oxidize LDL by a Thiol-dependent Mechanism
A Graham, JL Wood, VJ O'leary, D Stone |
Free Radical Research | 1996 |
Ceruloplasmin Enhances Smooth Muscle Cell- and Endothelial Cell-mediated Low Density Lipoprotein Oxidation by a Superoxide-dependent Mechanism
CK Mukhopadhyay, E Ehrenwald, PL Fox |
The Journal of biological chemistry | 1996 |
The Yin and Yang of Oxidation in the Development of the Fatty Streak: A Review Based on the 1994 George Lyman Duff Memorial Lecture
M Navab, JA Berliner, AD Watson, SY Hama, MC Territo, AJ Lusis, DM Shih, BJ Lenten, JS Frank, LL Demer, PA Edwards, AM Fogelman |
Arteriosclerosis, thrombosis, and vascular biology | 1996 |
Cosupplementation With Coenzyme Q Prevents the Prooxidant Effect of α-Tocopherol and Increases the Resistance of LDL to Transition Metal–Dependent Oxidation Initiation
SR Thomas, J Neužil, R Stocker |
Arteriosclerosis, thrombosis, and vascular biology | 1996 |
Drugs Affecting Lipid Metabolism
AM Gotto, R Paoletti, LC Smith, AL Catapano, AS Jackson |
1996 | |
Effect of alpha-tocopherol on restenosis after angioplasty in a model of experimental atherosclerosis
AM Lafont, YC Chai, JF Cornhill, PL Whitlow, PH Howe, GM Chisolm |
Journal of Clinical Investigation | 1995 |
Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide generation
JF Keaney, A Xu, D Cunningham, T Jackson, B Frei, JA Vita |
Journal of Clinical Investigation | 1995 |
Glutathione peroxidase potentiates the inhibition of platelet function by S-nitrosothiols
JE Freedman, B Frei, GN Welch, J Loscalzo |
Journal of Clinical Investigation | 1995 |
Human suction blister interstitial fluid prevents metal ion-dependent oxidation of low density lipoprotein by macrophages and in cell-free systems
AJ Dabbagh, B Frei |
Journal of Clinical Investigation | 1995 |
Beta-carotene inhibits atherosclerosis in hypercholesterolemic rabbits
A Shaish, A Daugherty, F O'Sullivan, G Schonfeld, JW Heinecke |
Journal of Clinical Investigation | 1995 |
Lipids and atherosclerosis
MJ Halpern |
Molecular Aspects of Medicine | 1995 |
Homocysteine and vascular disease
CS Berwanger, JY Jeremy, G Stansby |
British Journal of Surgery | 1995 |
Susceptibility of plasma low density lipoprotein to cupric ion—induced peroxidation in patients with variant angina
K Miwa, Y Miyagi, M Fujita |
Journal of the American College of Cardiology | 1995 |
Edta Differentially and Incompletely Inhibits Components of Prolonged Cell-Mediated Oxidation of Low-Density Lipoprotein
L Kritharides, W Jessup, RT Dean |
Free Radical Research | 1995 |
Systemic activation of 15-lipoxygenase in heart, lung, and vascular tissues by hypercholesterolemia: relationship to lipoprotein oxidation and atherogenesis
JM Bailey, AN Makheja, R Lee, TH Simon |
Atherosclerosis | 1995 |
Metabolism of modified LDL by cultured human placental cells
B Bonet |
Atherosclerosis | 1995 |
Oxidation of low-density lipoproteins: effect of antioxidant content, fatty acid composition and intrinsic phospholipase activity on susceptibility to metal ion-induced oxidation
KD Croft, P Williams, S Dimmitt, R Abu-Amsha, LJ Beilin |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1995 |
Iron Overload: Prevalence and Impact on Health
SR Lynch |
Nutrition Reviews | 1995 |
Copper-induced lipid peroxidation in liposomes, micelles, and LDL: Which is the role of vitamin E?
M Maiorino, A Zamburlini, A Roveri, F Ursini |
Free radical biology & medicine | 1995 |
Lowering of body iron stores by blood letting and oxidation resistance of serum lipoproteins: a randomized cross-over trial in male smokers
JT Salonen, H Korpela, K Nyyssönen, E Porkkala, TP Tuomainen, JD Belcher, DR JACOBS, R Salonen |
Journal of Internal Medicine | 1995 |
Body iron stores, dietary iron intake and coronary heart disease mortality
A Reunanen, H Takkunen, P Knekt, R Seppänen, A Aromaa |
Journal of Internal Medicine | 1995 |
Structure, oxidant activity, and cardiovascular mechanisms of human ceruloplasmin
PL Fox, C Mukhopadhyay, E Ehrenwald |
Life Sciences | 1995 |
The role of free radicals and antioxidants: How do we know that they are working?
MJ Thomas |
Critical Reviews in Food Science and Nutrition | 1995 |
Insights Into the Pathogenesis and Prevention of Coronary Artery Disease
JH O'Keefe, CJ Lavie, BD Mccallister |
Mayo Clinic Proceedings | 1995 |
Immunopharmacology of Free Radical Species
C Rice-Evans |
Immunopharmacology of Free Radical Species | 1995 |
Effect of in-vivo supplementation with low-dose vitamin E on susceptibility of low-density lipoprotein and high-density lipoprotein to oxidative modification
M Suzukawa, T Ishikawa, H Yoshida, H Nakamura |
Journal of the American College of Nutrition | 1995 |
Thyronines and probucol inhibition of human capillary endothelial cell-induced low density lipoprotein oxidation
AN Hanna, LC Titterington, LE Lantry, RE Stephens, HA Newman |
Biochemical Pharmacology | 1995 |
Diphenylhexatriene as a Fluorescent Probe for Monitoring Low Density Lipoprotein Peroxidation
JD Routier, C Mazière, FR Robert, M Auclair, R Santus, JC Mazière |
Free Radical Research | 1995 |
Prevention of atherosclerosis: The potential role of antioxidants
MR Mehra, CJ Lavie, HO Ventura, RV Milani |
Postgraduate Medicine | 1995 |
Atherosclerosis: Basic Mechanisms: Oxidation, Inflammation, and Genetics
JA Berliner, M Navab, AM Fogelman, JS Frank, LL Demer, PA Edwards, AD Watson, AJ Lusis |
Circulation | 1995 |
Iron Overload Augments the Development of Atherosclerotic Lesions in Rabbits
JA Araujo, EL Romano, BE Brito, V Parthé, M Romano, M Bracho, RF Montaño, J Cardier |
Arteriosclerosis, thrombosis, and vascular biology | 1995 |
Mast Cell Granule Remnants Carry LDL Into Smooth Muscle Cells of the Synthetic Phenotype and Induce Their Conversion Into Foam Cells
Y Wang, KA Lindstedt, PT Kovanen |
Arteriosclerosis, thrombosis, and vascular biology | 1995 |
Tissue Factor Pathway Inhibitor Activity Associated With LDL Is Inactivated by Cell- and Copper-Mediated Oxidation
P Lesnik, C Dentan, A Vonica, M Moreau, MJ Chapman |
Arteriosclerosis, thrombosis, and vascular biology | 1995 |
Active Oxygen in Biochemistry
JS Valentine, CS Foote, A Greenberg, JF Liebman |
1995 | |
Analysis of Free Radicals in Biological Systems
AE Favier, J Cadet, B Kalyanaraman, M Fontecave, JL Pierre |
1995 | |
Oxidative Stress and Antioxidant Defenses in Biology
S Ahmad |
1995 | |
Exchange of oxidized cholesteryl linoleate between LDL and HDL mediated by cholesteryl ester transfer protein
JK Christison, KA Rye, R Stocker |
Journal of lipid research | 1995 |
Oxidation of low density lipoprotein by iron or copper at acidic pH
J Morgan, DS Leake |
Journal of lipid research | 1995 |
Role of apolipoprotein B-derived radical and alpha-tocopheroxyl radical in peroxidase-dependent oxidation of low density lipoprotein
B Kalyanaraman, V Darley-Usmar, A Struck, N Hogg, S Parthasarathy |
Journal of lipid research | 1995 |
Formation of non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in plasma and low density lipoprotein exposed to oxidative stress in vitro
SM Lynch, JD Morrow, LJ 2nd, B Frei |
Journal of Clinical Investigation | 1994 |
Inhibition by interferon-gamma of human mononuclear cell-mediated low density lipoprotein oxidation. Participation of tryptophan metabolism along the kynurenine pathway
S Christen, SR Thomas, B Garner, R Stocker |
Journal of Clinical Investigation | 1994 |
Pathophysiological concentrations of glucose promote oxidative modification of low density lipoprotein by a superoxide-dependent pathway
M Kawamura, JW Heinecke, A Chait |
Journal of Clinical Investigation | 1994 |
Low density lipoproteins bind more to type I and III collagens by negative charge-dependent mechanisms than to type IV and V collagens
S Jimi, N Sakata, A Matunaga, S Takebayashi |
Atherosclerosis | 1994 |
Stimulation of low-density lipoprotein oxidation by insulin and insulin like growth factor I
VA Rifici, SH Schneider, AK Khachadurian |
Atherosclerosis | 1994 |
Calcium Channel Antagonists as Antioxidants
N Rojstaczer, DJ Triggle |
Cardiovascular Drug Reviews | 1994 |
LDL modification by activated polymorphonuclear leukocytes: A cellular model of mild oxidative stress
C Scaccini, I Jialal |
Free radical biology & medicine | 1994 |
Effects of supplementing with vitamin E on the uptake of low density lipoprotein and the stimulation of cholesteryl ester formation in macrophages
M Suzukawa, M Abbey, P Clifton, PJ Nestel |
Atherosclerosis | 1994 |
Lysophosphatidylcholine upregulates the level of heparin-binding epidermal growth factor-like growth factor mRNA in human monocytes
T Nakano, EW Raines, JA Abraham, M Klagsbrun, R Ross |
Proceedings of the National Academy of Sciences | 1994 |
The effect of iron overload on rat plasma and liver oxidant status in vivo
AJ Dabbagh, T Mannion, SM Lynch, B Frei |
Biochemical Journal | 1994 |
Generation of reactive oxygen species and activity of platelet-activating factor acetylhydrolase in human monocyte-derived macrophages
S Ruβwurm, S Krause, L Finkelberg, K Rühling, U Schauer, W Lösche |
Thrombosis Research | 1994 |
Photosensitizer targeting in photodynamic therapy II. Conjugates of haematoporphyrin with serum lipoproteins
MR Hamblin, EL Newman |
Journal of Photochemistry and Photobiology B Biology | 1994 |
Partitioning of chemically modified low-density lipoprotein in aqueous polymer two-phase systems
D Wiegel, O Richter, K Arnold |
Journal of Chromatography A | 1994 |
Natural Antioxidants in Human Health and Disease
M Levine, KR Dhariwal, Y Wang, JB Park, RW Welch |
Natural Antioxidants in Human Health and Disease | 1994 |
Human (THP-1) Macrophages Oxidize LDL by a Thiol-Dependent Mechanism
A Graham, JL Wood, VJ O'leary, D Stone |
Free Radical Research | 1994 |
Increased oxidazability of plasma low density lipoprotein from patients with coronary artery disease
HC Chiu, JR Jeng, SM Shieh |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 1994 |
Antiproliferative effect of desferrioxamine on vascular smooth muscle cells in vitro and in vivo
E Porreca, S Ucchino, CD Febbo, ND Bartolomeo, D Angelucci, AM Napolitano, A Mezzetti, F Cuccurullo |
Arteriosclerosis Thrombosis and Vascular Biology | 1994 |
PAF-acether-degrading acetylhydrolase in plasma LDL is inactivated by copper- and cell-mediated oxidation
C Dentan, P Lesnik, MJ Chapman, E Ninio |
Arteriosclerosis Thrombosis and Vascular Biology | 1994 |
Oxidation of LDL to a biologically active form by derivatives of nitric oxide and nitrite in the absence of superoxide. Dependence on pH and oxygen
GJ Chang, P Woo, HM Honda, LJ Ignarro, L Young, JA Berliner, LL Demer |
Arteriosclerosis Thrombosis and Vascular Biology | 1994 |
Free Radicals in Diagnostic Medicine
D Armstrong |
1994 | |
Tyrosyl radical generated by myeloperoxidase is a physiological catalyst for the initiation of lipid peroxidation in low density lipoprotein
ML Savenkova, DM Mueller, JW Heinecke |
The Journal of biological chemistry | 1994 |
Modified forms of low-density lipoprotein and atherosclerosis
D Steinberg |
Journal of Internal Medicine | 1993 |
Probucol as an antioxidant and antiatherogenic drug
M Kuzuya, F Kuzuya |
Free radical biology & medicine | 1993 |
Oxidized low-density lipoprotein in experimental focal glomerulosclerosis
AB Magil, JJ Frohlich, SM Innis, UP Steinbrecher |
Kidney International | 1993 |
The Gordon Wilson Lecture. Plasma cholesterol: atherogenesis and mortality
WR Fisher |
Transactions of the American Clinical and Climatological Association | 1993 |
Oxidation of low-density lipoprotein with hypochlorite causes transformation of the lipoprotein into a high-uptake form for macrophages
LJ Hazell, R Stocker |
Biochemical Journal | 1993 |
Role of oxidised low density lipoprotein in atherogenesis
JL Witztum |
British heart journal | 1993 |
Physical changes of low-density lipoprotein on oxidation
JN Herak |
Chemistry and Physics of Lipids | 1993 |
Influence of culture medium characteristics on the ability to oxidize low-density lipoproteins
MA Pech, I Myara, N Moatti, A Caprani |
Bioelectrochemistry and Bioenergetics | 1993 |
Prooxidant role of vitamin E in copper induced lipid peroxidation
M Maiorino, A Zamburlini, A Roveri, F Ursini |
FEBS Letters | 1993 |
In vitro formation of oxidatively-modified and reassembled human low-density lipoproteins: Antioxidant effect of albumin
A Dobrian, R Mora, M Simionescu, N Simionescu |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1993 |
Inhibition of low density lipoprotein oxidation by thyronines and probucol
AN Hanna, DR Feller, DT Witiak, HA Newman |
Biochemical Pharmacology | 1993 |
The Early Atherosclerotic Lesion — Morphology and Mechanisms
J Nilsson |
1993 | |
Inhibition of copper-mediated oxidation of LDL by rat serosal mast cells. A novel cellular protective mechanism involving proteolysis of the substrate under oxidative stress
KA Lindstedt, JO Kokkonen, PT Kovanen |
Arteriosclerosis Thrombosis and Vascular Biology | 1993 |
Macrophages and Related Cells
MA Horton |
1993 | |
Free Radicals: from Basic Science to Medicine
G Poli, E Albano, MU Dianzani |
1993 | |
Cellular Metabolism of the Arterial Wall and Central Nervous System
G Schettler, H Greten, AJ Habenicht |
1993 | |
Mechanisms of copper- and iron-dependent oxidative modification of human low density lipoprotein
SM Lynch, B Frei |
Journal of lipid research | 1993 |
The action of oxidized low density lipoprotein on calcium transients in isolated rabbit cardiomyocytes
K Liu, H Massaeli, GN Pierce |
The Journal of biological chemistry | 1993 |
Inhibition of macrophage-mediated low density lipoprotein oxidation by stimulated rat serosal mast cells
KA Lindstedt |
The Journal of biological chemistry | 1993 |
Cellular oxidation of low density lipoprotein is caused by thiol production in media containing transition metal ions
CP Sparrow, J Olszewski |
Journal of lipid research | 1993 |
Oxidation of low density lipoprotein by thiols: superoxide-dependent and -independent mechanisms
JW Heinecke, M Kawamura, L Suzuki, A Chait |
Journal of lipid research | 1993 |
Content of antioxidants, preformed lipid hydroperoxides, and cholesterol as predictors of the susceptibility of human LDL to metal ion-dependent and -independent oxidation
B Frei, JM Gaziano |
Journal of lipid research | 1993 |
Free radicals, lipoproteins and cardiovascular dysfunction
C Rice-Evans, KR Bruckdorfer |
Molecular Aspects of Medicine | 1992 |
Role of oxidized low density lipoprotein in atherogenesis
S Parthasarathy, SM Rankin |
Progress in Lipid Research | 1992 |
The role of lipid peroxidation and antioxidants in oxidative modification of LDL
H Esterbauer, J Gebicki, H Puhl, G Jürgens |
Free radical biology & medicine | 1992 |
A protective role for nitric oxide in the oxidative modification of low density lipoproteins by mouse macrophages
MT Yates, LE Lambert, JP Whitten, I McDonald, M Mano, G Ku, SJ Mao |
FEBS Letters | 1992 |
Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis
SK Clinton, R Underwood, L Hayes, ML Sherman, DW Kufe, P Libby |
The American Journal of Pathology | 1992 |
Immunohistochemical distribution of lipoprotein epitopes in xanthomata from patients with familial hypercholesterolemia
N Sugiyama, S Marcovina, AM Gown, H Seftel, B Joffe, A Chait |
The American Journal of Pathology | 1992 |
Studies on epitopes on low-density lipoprotein modified by 4-hydroxynonenal. Biochemical characterization and determination
Q Chen, H Esterbauer, G Jürgens |
Biochemical Journal | 1992 |
Lysolecithin actions on vascular smooth muscle cells
R Locher, B Weisser, T Mengden, C Brunner, W Vetter |
Biochemical and Biophysical Research Communications | 1992 |
Inhibition of human low-density lipoprotein oxidation in vitro by Maharishi Ayur-Veda herbal mixtures
HM Sharma, AN Hanna, EM Kauffman, HA Newman |
Pharmacology Biochemistry and Behavior | 1992 |
Lipid peroxidation — a common pathogenetic mechanism?
R Dargel |
Experimental and Toxicologic Pathology | 1992 |
Malondialdehyde modification and copper-induced autooxidation of high-density lipoprotein decrease cholesterol efflux from human cultured fibroblasts
S Salmon, C Maziére, M Auclair, L Theron, R Santus, JC Maziére |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1992 |
Role of lipoprotein-copper complex in copper catalyzed-peroxidation of low-density lipoprotein
M Kuzuya, K Yamada, T Hayashi, C Funaki, M Naito, K Asai, F Kuzuya |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1992 |
The influence of medium components on Cu2+-dependent oxidation of low-density lipoproteins and its sensitivity to superoxide dismutase
CE Thomas |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1992 |
The Role of Iron in Oxygen-Mediated Toxicities
TP Ryan, SD Aust |
Critical Reviews in Toxicology | 1992 |
The participation of nitric oxide in cell free- and its restriction of macrophage-mediated oxidation of low-density lipoprotein
W Jessup, D Mohr, SP Gieseg, RT Dean, R Stocker |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 1992 |
Supplementation with vitamin E but not beta-carotene in vivo protects low density lipoprotein from lipid peroxidation in vitro. Effect of cigarette smoking
HM Princen, G van Poppel, C Vogelezang, R Buytenhek, FJ Kok |
Arteriosclerosis Thrombosis and Vascular Biology | 1992 |
Oxidatively modified HDLs are potent inhibitors of cholesterol biosynthesis in human skin fibroblasts
G Ghiselli, L Giorgini, M Gelati, R Musanti |
Arteriosclerosis Thrombosis and Vascular Biology | 1992 |
Endothelial Cell Dysfunctions
N Simionescu, M Simionescu |
1992 | |
Role of oxidized human plasma low density lipoproteins in atherosclerosis: effects on smooth muscle cell proliferation
S Chatterjee |
Molecular and Cellular Biochemistry | 1992 |
Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts
S Ylä-Herttuala, ME Rosenfeld, S Parthasarathy, E Sigal, T Särkioja, JL Witztum, D Steinberg |
Journal of Clinical Investigation | 1991 |
Role of oxidized low density lipoprotein in atherogenesis
JL Witztum, D Steinberg |
Journal of Clinical Investigation | 1991 |
Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein 1 synthesis and is abolished by high density lipoprotein
M Navab, SS Imes, SY Hama, GP Hough, LA Ross, RW Bork, AJ Valente, JA Berliner, DC Drinkwater, H Laks |
Journal of Clinical Investigation | 1991 |
Enzymic mechanisms of superoxide production
AR Cross, OT Jones |
Biochimica et Biophysica Acta (BBA) - Bioenergetics | 1991 |
The spin trap, α-phenyl N-tert-butylnitrone, inhibits the oxidative modification of low density lipoprotein
B Kalyanaraman, J Joseph, S Parthasarathy |
FEBS Letters | 1991 |
Effect of Antioxidants on Oxidative Modification of LDL
H Esterbauer, H Puhl, M Dieber-rotheneder, G Waeg, H Rabl |
Annals of Medicine | 1991 |
Antioxidants and atherosclerosis: A current assessment
GM Chisolm |
Clinical Cardiology | 1991 |
Therapeutic potential of vitamin E in the pathogenesis of spontaneous atherosclerosis
DR Janero |
Free radical biology & medicine | 1991 |
Oxidized Low Density Lipoproteins: a Role in the Pathogenesis of Atherosclerosis in Diabetes?
TJ Lyons |
Diabetic Medicine | 1991 |
Gas phase oxidants of cigarette smoke induce lipid peroxidation and changes in lipoprotein properties in human blood plasma. Protective effects of ascorbic acid
B Frei, TM Forte, BN Ames, CE Cross |
Biochemical Journal | 1991 |
New trends in photobiology
I Freitas, GF Baronzio |
Journal of Photochemistry and Photobiology B Biology | 1991 |
Oxidative Damage & Repair
A Sevanian |
Oxidative Damage & Repair | 1991 |
Oxidation of low-density lipoprotein by copper and iron in phosphate buffer
K Masafumi, Y Kazuyoshi, H Toshio, F Chiaki, N Michitaka, A Kanichi, K Fumio |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1991 |
Enhanced in vitro oxidation of plasma lipoproteins derived from hypercholesterolemic patients
A Lavy, GJ Brook, G Dankner, AB Amotz, M Aviram |
Metabolism | 1991 |
Calcium Antagonists Prevent Monocyte and Endothelial Cell-Induced Modification of Low Density Lipoproteins
C Breugnot, C Mazière, M Auclair, L Mora, MF Ronveaux, S Salmon, R Santus, P Morlière, A Lenaers, JC Mazière |
Free Radical Research | 1991 |
Epr Evidence for the Oxidation-Induced Formation of Negatively Charged Species on the Low-Density Lipoprotein Surface
J Brnjas-Kraljević, G Pifat, JN Herak, G Jürgens |
Free Radical Research | 1991 |
The liver metabolite S-422 of the hypolipidaemic drug benfluorex decreases cholesterol esterification in fibroblasts and monocyte-like cells
JC Mazire, C Mazire, M Auclair, L Mora, O Arnaud |
European Journal of Clinical Pharmacology | 1991 |
Lipid peroxide and transition metals are required for the toxicity of oxidized low density lipoprotein to cultured endothelial cells
M Kuzuya, M Naito, C Funaki, T Hayashi, K Asai, F Kuzuya |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 1991 |
Ultraviolet-treated lipoproteins as a model system for the study of the biological effects of lipid peroxides on cultured cells. III. The protective effect of antioxidants (probucol, catechin, vitamin E) against the cytotoxicity of oxidized LDL occurs in two different ways
A Negre-Salvayre, Y Alomar, M Troly, R Salvayre |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 1991 |
Phagocytosis of lipase-aggregated low density lipoprotein promotes macrophage foam cell formation. Sequential morphological and biochemical events
JW Heinecke, AG Suits, M Aviram, A Chait |
Arteriosclerosis Thrombosis and Vascular Biology | 1991 |
Attenuation of atherosclerosis in a modified strain of hypercholesterolemic Watanabe rabbits with use of a probucol analogue (MDL 29,311) that does not lower serum cholesterol
SJ Mao, MT Yates, RA Parker, EM Chi, RL Jackson |
Arteriosclerosis Thrombosis and Vascular Biology | 1991 |
Enhanced susceptibility to in vitro oxidation of the dense low density lipoprotein subfraction in healthy subjects
J de Graaf, HL Hak-Lemmers, MP Hectors, PN Demacker, JC Hendriks, AF Stalenhoef |
Arteriosclerosis Thrombosis and Vascular Biology | 1991 |
Effects of copper and histidine on oxidative modification of low density lipoprotein and its subsequent binding to collagen
N Kalant, S McCormick, MA Parniak |
Arteriosclerosis Thrombosis and Vascular Biology | 1991 |
Atherosclerosis: Cellular and Molecular Interactions in the Artery Wall
AI Gotlieb, BL Langille, S Fedoroff |
Atherosclerosis | 1991 |
Activated platelets secrete a protein-like factor that stimulates oxidized-LDL receptor activity in macrophages
B Fuhrman, GJ Brook, M Aviram |
Journal of lipid research | 1991 |
Fractionation of charge-modified low density lipoproteins by fast protein liquid chromatography
B Vedie, I Myara, MA Pech, JC Maziere, C Maziere, A Caprani, N Moatti |
Journal of lipid research | 1991 |
Uptake and degradation of low density lipoproteins in atherosclerotic rabbit aorta: role of local LDL modification
O Wiklund, L Mattsson, T Björnheden, G Camejo, G Bondjers |
Journal of lipid research | 1991 |
Oxidation-labile subfraction of human plasma low density lipoprotein isolated by ion-exchange chromatography
H Shimano, N Yamada, S Ishibashi, H Mokuno, N Mori, T Gotoda, K Harada, Y Akanuma, T Murase, Y Yazaki |
Journal of lipid research | 1991 |
Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophages
SM Rankin, S Parthasarathy, D Steinberg |
Journal of lipid research | 1991 |
Minimally modified low density lipoprotein stimulates monocyte endothelial interactions
JA Berliner, MC Territo, A Sevanian, S Ramin, JA Kim, B Bamshad, M Esterson, AM Fogelman |
Journal of Clinical Investigation | 1990 |
Oxidized low density lipoproteins cause contraction and inhibit endothelium-dependent relaxation in the pig coronary artery
BC Simon, LD Cunningham, RA Cohen |
Journal of Clinical Investigation | 1990 |
Role of oxidatively modified LDL in atherosclerosis
UP Steinbrecher, H Zhang, M Lougheed |
Free radical biology & medicine | 1990 |
Atherogenic Lipoproteins Resulting from Genetic Defects of Apolipoproteins B and E
KH Weisgraber, TL Innerarity, SC Rall, RW Mahley |
Annals of the New York Academy of Sciences | 1990 |
Effect of Eicosapentaenoic Acid on the Binding and Degradation of Oxidized LDL and the Production of LTB4, LTC4, and PGE2in Rat Peritoneal Macrophages
KJ Chang, H Saito, Y Tamura, S Yoshida |
Annals of the New York Academy of Sciences | 1990 |
Oxidation of low-density lipoprotein by Cu2+ and lipoxygenase: an electron spin resonance study
B Kalyanaraman, WE Antholine, S Parthasarathy |
Biochimica et Biophysica Acta (BBA) - General Subjects | 1990 |
Oxidized low density lipoprotein induces differentiation and adhesion of human monocytes and the monocytic cell line U937
J Frostegård, J Nilsson, A Haegerstrand, A Hamsten, H Wigzell, M Gidlund |
Proceedings of the National Academy of Sciences | 1990 |
The oxidative modification of low-density lipoproteins by macrophages
DS Leake, SM Rankin |
Biochemical Journal | 1990 |
Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions
S Ylä-Herttuala, ME Rosenfeld, S Parthasarathy, CK Glass, E Sigal, JL Witztum, D Steinberg |
Proceedings of the National Academy of Sciences | 1990 |
Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells
SD Cushing, JA Berliner, AJ Valente, MC Territo, M Navab, F Parhami, R Gerrity, CJ Schwartz, AM Fogelman |
Proceedings of the National Academy of Sciences | 1990 |
Alpha-tocopherol consumption during low-density-lipoprotein oxidation
W Jessup, SM Rankin, CV de Whalley, JR Hoult, J Scott, DS Leake |
Biochemical Journal | 1990 |
Sensitivity of tryptophan and related compounds to oxidation induced by lipid autoperoxidation. Application to human serum low- and high-density lipoproteins
JP Reyftmann, R Santus, JC Mazière, P Morlière, S Salmon, C Candide, C Mazière, J Haigle |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1990 |
Ultraviolet-treated lipoproteins as a model system for the study of the biological effects of lipid peroxides on cultured cell. I. Chemical modifications of ultraviolet-treated low-density lipoproteins
N Dousset, A Negre-Salvayre, M Lopez, R Salvayre, L Douste-Blazy |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1990 |
Ultraviolet-treated lipoproteins as a model system for the study of the biological effects of lipid peroxides on cultured cells. II. Uptake and cytotoxicity of ultraviolet-treated LDL on lymphoid cell lines
A Negre-Salvayre, M Lopez, T Levade, MT Pieraggi, N Dousset, L Douste-Blazy, R Salvayre |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1990 |
Activation of soluble guanylate cyclase by nitrovasodilators is inhibited by oxidized low-density lipoprotein
K Schmidt, WF Graier, GM Kostner, B Mayer, WR Kukovetz |
Biochemical and Biophysical Research Communications | 1990 |
Free radical generation by early glycation products: A mechanism for accelerated atherogenesis in diabetes
CJ Mullarkey, D Edelstein, M Brownlee |
Biochemical and Biophysical Research Communications | 1990 |
Phenothiazines inhibit copper and endothelial cell-induced peroxidation of low density lipoprotein
C Breugnot, C Mazière, S Salmon, M Auclair, R Santus, P Morlière, A Lenaers, JC Mazière |
Biochemical Pharmacology | 1990 |
Flavonoids inhibit the oxidative modification of low density lipoproteins by macrophages
CV de Whalley, SM Rankin, JR Hoult, W Jessup, DS Leake |
Biochemical Pharmacology | 1990 |
Free Radicals, Lipoproteins, and Membrane Lipids
AC de Paulet, L Douste-Blazy, R Paoletti |
1990 | |
Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein
W Palinski, S Ylä-Herttuala, ME Rosenfeld, SW Butler, SA Socher, S Parthasarathy, LK Curtiss, JL Witztum |
Arteriosclerosis (Dallas, Tex.) | 1990 |
Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits
ME Rosenfeld, W Palinski, S Ylä-Herttuala, S Butler, JL Witztum |
Arteriosclerosis (Dallas, Tex.) | 1990 |
Hypercholesterolemia, Hypocholesterolemia, Hypertriglyceridemia, in Vivo Kinetics
CL Malmendier, P Alaupovic, HB Brewer |
1990 | |
Macrophages, Endothelial Cells, and Lipoprotein Oxidation in the Pathogenesis of Atherosclerosis*
ME Rosenfeld, W Palinski, S Ylä-Herttuala, TE Carew |
Toxicologic pathology | 1990 |
Lipid hydroperoxy and hydroxy derivatives in copper-catalyzed oxidation of low density lipoprotein
ML Lenz, H Hughes, , DP Via, , AA Taylor, AM Gotto, CV Smith |
Journal of lipid research | 1990 |
Vitamin E and other Lipophilic Antioxidants Protect LDL against Oxidation
H Esterbauer, M Rotheneder, G Striegl, G Waeg, A Ashy, W Sattler, G Jürgens |
Fett Wissenschaft Technologie/Fat Science Technology | 1989 |
Macrophages modify β-VLDL by proteolysis and enhance subsequent lipid accumulation in arterial smooth muscle cells
JB Davis, DE Bowyer |
Atherosclerosis | 1989 |
The action of defined oxygen-centred free radicals on human low-density lipoprotein
S Bedwell, RT Dean, W Jessup |
Biochemical Journal | 1989 |
Phagocytosis of aggregated lipoprotein by macrophages: low density lipoprotein receptor-dependent foam-cell formation
AG Suits, A Chait, M Aviram, JW Heinecke |
Proceedings of the National Academy of Sciences | 1989 |
Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit
HC Boyd, AM Gown, G Wolfbauer, A Chait |
The American Journal of Pathology | 1989 |
The iron paradigm of ischemic heart disease
JL Sullivan |
American Heart Journal | 1989 |
Role of biologically modified low-density lipoprotein in atherosclerosis
TE Carew |
The American Journal of Cardiology | 1989 |
Beyond Cholesterol
FH Epstein, D Steinberg, S Parthasarathy, TE Carew, JC Khoo, JL Witztum |
New England Journal of Medicine | 1989 |
Effect of probucol on the physical properties of low-density lipoproteins oxidized by copper
LR McLean, KA Hagaman |
Biochemistry | 1989 |
Probucol does not affect lipoprotein metabolism in macrophages of Watanabe heritable hyperlipidemic rabbits
Y Nagano, T Kita, M Yokode, K Ishii, N Kume, H Otani, H Arai, C Kawai |
Arteriosclerosis (Dallas, Tex.) | 1989 |
Modification of low density lipoprotein with 4-hydroxynonenal induces uptake by macrophages
HF Hoff, J O'Neil, GM rd, TB Cole, O Quehenberger, H Esterbauer, G Jürgens |
Arteriosclerosis (Dallas, Tex.) | 1989 |
Diseases of the Arterial Wall
JP Camilleri, CL Berry, JN Fiessinger, J Bariéty |
1989 | |
Differences in the metabolism of oxidatively modified low density lipoprotein and acetylated low density lipoprotein by human endothelial cells: inhibition of cholesterol esterification by oxidatively modified low density lipoprotein
I Jialal, A Chait |
Journal of lipid research | 1989 |
Concentration-dependent antioxidant activity of probucol in low density lipoproteins in vitro: probucol degradation precedes lipoprotein oxidation
RL Barnhart, SJ Busch, RL Jackson |
Journal of lipid research | 1989 |
Lipid Peroxidation Changes the Expression of Specific Epitopes of Apolipoprotein A-I
YL Marcel, D Jewer, L Leblond, PK Weech, RW Milne |
The Journal of biological chemistry | 1989 |
Probucol: A Reappraisal of its Pharmacological Properties and Therapeutic Use in Hypercholesterolaemia
MM Buckley, KL Goa, AH Price, RN Brogden |
Drugs | 1989 |
Stimulated arachidonate metabolism during foam cell transformation of mouse peritoneal macrophages with oxidized low density lipoprotein
M Yokode, T Kita, Y Kikawa, T Ogorochi, S Narumiya, C Kawai |
Journal of Clinical Investigation | 1988 |
Oxidative modification of low density lipoprotein (LDL) by activated human monocytes and the cell lines U937 and HL60
MK Cathcart, GM Chisolm, AK McNally, DW Morel |
In Vitro Cellular & Developmental Biology | 1988 |
Apolipoproteins, Dyslipoproteinaemia and Premature Coronary Heart Disease
A Hamsten |
Acta Medica Scandinavica | 1988 |
Extracts of human atherosclerotic lesions can modify low density lipoproteins leading to enhanced uptake by macrophages
HF Hoff, J O'Neil |
Atherosclerosis | 1988 |
Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis
MT Quinn, S Parthasarathy, D Steinberg |
Proceedings of the National Academy of Sciences | 1988 |
Cholesteryl ester accumulation in macrophages incubated with low density lipoprotein pretreated with cigarette smoke extract
M Yokode, T Kita, H Arai, C Kawai, S Narumiya, M Fujiwara |
Proceedings of the National Academy of Sciences | 1988 |
Role of superoxide in endothelial-cell modification of low-density lipoproteins
UP Steinbrecher |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1988 |
Advances in Genetics
BH Bowman, F Yang, GS Adrian |
Advances in genetics | 1988 |
Lipoprotein oxidation and cytotoxicity: Effect of probucol on streptozotocin-treated rats
GM Chisolm, DW Morel |
The American Journal of Cardiology | 1988 |
Prevention of atherosclerotic progression in Watanabe rabbits by probucol
T Kita, Y Nagano, M Yokode, K Ishii, N Kume, S Narumiya, C Kawai |
The American Journal of Cardiology | 1988 |
Preferential metabolism by macrophages of conditioned rabbit hypercholesterolemic remnant lipoproteins
D Haratz, O Stein, R Shwartz, EM Berry, Y Stein |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1988 |
Interaction of native and cell-modified low density lipoprotein with collagen gel
GA Hoover, S McCormick, N Kalant |
Arteriosclerosis (Dallas, Tex.) | 1988 |
Copper and Zinc in Inflammation
R Milanino, KD Rainsford, GP Velo |
1988 | |
Oxidative modification of low density lipoprotein (LDL) by activated human monocytes and the cell lines U937 and HL60
MK Cathcart, GM Chisolm, AK McNally, DW Morel |
In Vitro Cellular & Developmental Biology – Animal | 1988 |
Toxicity of oxidized low-density lipoprotein to cultured fibroblasts is selective for S phase of the cell cycle
K Kosugi, DW Morel, PE DiCorleto, GM Chisolm |
Journal of Cellular Physiology | 1987 |
MACROPHAGES AND ATHEROGENESIS
MJ Mitchinson, RY Ball |
The Lancet | 1987 |
Free radical modification of low-density lipoprotein: Mechanisms and biological consequences
JW Heinecke |
Free radical biology & medicine | 1987 |
Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia
T Kita, Y Nagano, M Yokode, K Ishii, N Kume, A Ooshima, H Yoshida, C Kawai |
Proceedings of the National Academy of Sciences | 1987 |
Modification of human serum low density lipoprotein by oxidation — Characterization and pathophysiological implications
G Jürgens, HF Hoff, GM Chisolm, H Esterbauer |
Chemistry and Physics of Lipids | 1987 |
Immunological detection of low-density lipoproteins modified by malondialdehyde in vitro or in vivo
S Salmon, C Maziere, L Theron, I Beucler, M Ayrault-Jarrier, S Goldstein, J Polonovski |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1987 |
Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL. Correlation with changes in receptor-mediated catabolism
UP Steinbrecher, JL Witztum, S Parthasarathy, D Steinberg |
Arteriosclerosis (Dallas, Tex.) | 1987 |
Lipoprotein-mediated inhibition of endothelial cell production of platelet-derived growth factor-like protein depends on free radical lipid peroxidation
PL Fox, GM Chisolm, PE DiCorleto |
The Journal of biological chemistry | 1987 |
The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells
JW Heinecke, H Rosen, LA Suzuki, A Chait |
The Journal of biological chemistry | 1987 |
Nonenzymatic oxidative cleavage of peptide bonds in apoprotein B-100
LG Fong, S Parthasarathy, JL Witztum, D Steinberg |
Journal of lipid research | 1987 |
Oxidation of human low density lipoprotein results in derivatization of lysine residues of apolipoprotein B by lipid peroxide decomposition products
UP Steinbrecher |
The Journal of biological chemistry | 1987 |
Superoxide-mediated modification of low density lipoprotein by arterial smooth muscle cells
JW Heinecke, L Baker, H Rosen, A Chait |
Journal of Clinical Investigation | 1986 |
Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine
G Starkebaum, JM Harlan |
Journal of Clinical Investigation | 1986 |
Effects of reagent and cell-generated hydrogen peroxide on the properties of low density lipoprotein
RR Montgomery, CF Nathan, ZA Cohn |
Proceedings of the National Academy of Sciences | 1986 |
Studies on the mechanism of action of probucol
D Steinberg |
The American Journal of Cardiology | 1986 |
Role of endothelial cells and their products in the modification of low-density lipoproteins
VW van Hinsbergh, M Scheffer, L Havekes, HJ Kempen |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1986 |
Essential role of phospholipase A2 activity in endothelial cell-induced modification of low density lipoprotein
S Parthasarathy, UP Steinbrecher, J Barnett, JL Witztum, D Steinberg |
Proceedings of the National Academy of Sciences | 1985 |
The behaviour of caeruloplasmin in stored human extracellular fluids in relation to ferroxidase II activity, lipid peroxidation and phenanthroline-detectable copper
JM Gutteridge, PG Winyard, DR Blake, J Lunec, S Brailsford, B Halliwell |
Biochemical Journal | 1985 |
New Comprehensive Biochemistry
S Yamamoto |
New Comprehensive Biochemistry | 1983 |