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Citations to this article

Regulation of Glycosaminoglycan Synthesis by Thyroid Hormone in Vitro
Terry J. Smith, … , Louis Philipson, Samuel Refetoff
Terry J. Smith, … , Louis Philipson, Samuel Refetoff
Published November 1, 1982
Citation Information: J Clin Invest. 1982;70(5):1066-1073. https://doi.org/10.1172/JCI110694.
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Regulation of Glycosaminoglycan Synthesis by Thyroid Hormone in Vitro

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Abstract

Human skin fibroblasts synthesize and accumulate glycosaminoglycans (GAG). Recently, we reported that fibroblasts incubated in thyroid hormone-deficient media accumulate more GAG than do cultures incubated in the same media enriched with 0.1 μM triiodothyronine (T3) (1981. Endocrinology. 108: 2397). The current study characterizes that enhanced accumulation. Confluent cultures were maintained in thyroid hormone-deficient media without or with added T3, labeled with [3H]acetate and analyzed for total [3H]GAG and [3H]hyaluronic acid content.

Authors

Terry J. Smith, Yoshiharu Murata, Allen L. Horwitz, Louis Philipson, Samuel Refetoff

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Total citations by year

Year: 2023 2022 2021 2020 2019 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2006 2005 2004 2003 2002 2000 1999 1998 1996 1995 1994 1993 1990 1989 1988 1987 1986 1985 1984 Total
Citations: 2 1 2 3 3 3 1 2 1 4 1 2 1 1 2 2 2 2 2 1 1 4 1 2 3 5 5 1 1 5 2 2 2 2 74
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JY Chuo, TY Lee, H Hollands, AH Morris, RC Reyes, JD Rossiter, SP Meredith, DA Maberley
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T Helper Type 1 and Type 2 Cytokines Exert Divergent Influence on the Induction of Prostaglandin E2 and Hyaluronan Synthesis by Interleukin-1β in Orbital Fibroblasts: Implications for the Pathogenesis of Thyroid-Associated Ophthalmopathy
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Thyroid Hormone Enhances Aggrecanase-2/ADAM-TS5 Expression and Proteoglycan Degradation in Growth Plate Cartilage
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Cultured Human Fibroblasts Express Constitutive IL-16 mRNA: Cytokine Induction of Active IL-16 Protein Synthesis Through a Caspase-3-Dependent Mechanism
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Resistance to Thyroid Hormone Caused by a New Mutation (V336M) in the Thyroid Hormone Receptor β Gene
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Thyroid 1999
HMC-1 Mast Cells Activate Human Orbital Fibroblasts in Coculture: Evidence for Up-Regulation of Prostaglandin E2 and Hyaluronan Synthesis*
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Endocrinology 1999
Expression of Hyaluronan Synthase Messenger Ribonucleic Acids and Their Induction by Interleukin-1β in Human Orbital Fibroblasts: Potential Insight into the Molecular Pathogenesis of Thyroid-Associated Ophthalmopathy1
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The Journal of clinical endocrinology and metabolism 1999
Activation of Human Orbital Fibroblasts through CD40 Engagement Results in a Dramatic Induction of Hyaluronan Synthesis and Prostaglandin Endoperoxide H Synthase-2 Expression: INSIGHTS INTO POTENTIAL PATHOGENIC MECHANISMS OF THYROID-ASSOCIATED OPHTHALMOPATHY
HJ Cao, HS Wang, Y Zhang, HY Lin, RP Phipps, TJ Smith
The Journal of biological chemistry 1998
The putative role of cytokine-orbital fibroblast interactions in the pathogenesis of thyroid-associated ophthalmopathy
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Orbit 1996
Molecular Cloning of a Novel Thyroid Hormone-responsive Gene, ZAKI-4 , in Human Skin Fibroblasts
T Miyazaki, Y Kanou, Y Murata, S Ohmori, T Niwa, K Maeda, H Yamamura, H Seo
The Journal of biological chemistry 1996
Bone and joint manifestations of hypothyroidism
RM McLean, DN Podell
Seminars in Arthritis and Rheumatism 1995
Effects of Thyro-Parathyroidectomy and Parathyroidectomy upon Dentinogenesis: Part I: Light Microscopy
H Chardin, AC Acevedo, D Septier, JF Staub, M Goldberg
Connective Tissue Research 1995
Leukoregulin induces plasminogen activator inhibitor type 1 in human orbital fibroblasts
MG Hogg, CH Evans, TJ Smith
American journal of physiology. Cell physiology 1995
Mutations of CpG dinucleotides located in the triiodothyronine (T3)-binding domain of the thyroid hormone receptor (TR) beta gene that appears to be devoid of natural mutations may not be detected because they are unlikely to produce the clinical phenotyp
Y Hayashi, T Sunthornthepvarakul, S Refetoff
Journal of Clinical Investigation 1994
Prostaglandin E2 elicits a morphological change in cultured orbital fibroblasts from patients with Graves ophthalmopathy
TJ Smith, HS Wang, MG Hogg, RC Henrikson, CR Keese, I Giaever
Proceedings of the National Academy of Sciences 1994
Hyaluronan Metabolism in Skin
R Tammi, UM Ågren, AL Tuhkanen, M Tammi
Progress in Histochemistry and Cytochemistry 1994
Ultrastructure of cultured human orbital fibroblasts
RC Henrikson, TJ Smith
Cell and Tissue Research 1994
Regulation of lysosomal sulfate transport by thyroid hormone
HF Chou, M Passage, AJ Jonas
The Journal of biological chemistry 1994
Effect of therapy for thyroid dysfunction on musculoskeletal symptoms
M Kloppenburg, BA Dijkmans, JJ Rasker
Clinical Rheumatology 1993
Interferon Gamma Regulation of De Novo Protein Synthesis in Human Dermal Fibroblasts in Culture Is Anatomic Site Dependent
TJ Smith, PJ Higgins
Journal of Investigative Dermatology 1993
Surgical Endocrinology
M Press
Surgical Endocrinology 1993
Pleotrophic action of interferon gamma in human orbital fibroblasts
PJ Higgins, TJ Smith
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1993
Bidimensional gel electrophoretic analysis of protein synthesis and response to interferon-γ in cultured human dermal fibroblasts
TJ Smith, PJ Higgins
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1993
Thyroid Function & Disease
JH Oppenheimer
Thyroid Function & Disease 1990
The Vitreous
J Sebag
1989
Keratinocytes Convert Thyroxine to Triiodothyronine
MM Kaplan, PR Gordon, C Pan, JK Lee, BA Gilchrest
Annals of the New York Academy of Sciences 1988
Effect of Thyroid Hormone Deficiency on Proteoglycan Synthesis by Human Skin Fibroblast Cultures
Y Shishiba, M Yanagishita, VC Hascall
Connective Tissue Research 1988
Glucocorticoid regulation of glycosaminoglycan synthesis in cultured human skin fibroblasts: Evidence for a receptor-mediated mechanism involving effects on specific de novo protein synthesis
TJ Smith
Metabolism 1988
3,3′,5-L-triiodothyronine but not L-thyroxine can block the induction of tyrosinase by imidazole in cultured B16 melanoma cells
TJ Smith, EL Kline
Biochemical and Biophysical Research Communications 1988
3 Clinical pathophysiology and metabolic effects of hypothyroidism
U Bürgi, MP König
Baillière's Clinical Endocrinology and Metabolism 1988
n-Butyrate inhibition of hyaluronate synthesis in cultured human fibroblasts
TJ Smith
Journal of Clinical Investigation 1987
Thyroid and Glucocorticoid Hormone Regulation of specific Protein Abundance in Cultured Human Skin Fibroblasts
RE Davis, TJ Smith
Endocrine Research 1987
Nuclear thyroid hormone receptors in cultured human fibroblasts: Improved method of isolation, partial characterization, and interaction with chromatin
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Angiotensin-converting enzyme: Characteristics in human skin fibroblasts
RC Smallridge, GT Gamblin, C Eil
Metabolism 1986
Chemically Induced Renal Papillary Necrosis and Upper Urothelial Carcinoma. Part 2
PH Bach, JW Bridges, GH Mudge
Critical Reviews in Toxicology 1985
Glucocorticoid Regulation of Glycosaminoglycan Accumulation in Murine Fibroblasts
TJ Smith
Endocrine Research 1985
Dexamethasone regulation of glycosaminoglycan synthesis in cultured human skin fibroblasts. Similar effects of glucocorticoid and thyroid hormones
TJ Smith
Journal of Clinical Investigation 1984
Effects of 3,5,3'-triiodothyronine on collagen synthesis by cultured human skin fibroblasts
C Rycker, JL Vandalem, G Hennen
FEBS Letters 1984

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