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Complex formation of platelet membrane glycoproteins IIb and IIIa with fibrinogen.

R L Nachman, L L Leung

R L Nachman, L L Leung

Published February 1, 1982
Citation Information: J Clin Invest. 1982;69(2):263-269. https://doi.org/10.1172/JCI110448.

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Citations to this article (236)

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Platelet biology of the rapidly failing lung AV Washington, O Esponda, A Gibson	British Journal of Haematology	2019
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Using flow cytometry to monitor glycoprotein IIb-IIIa activation AL Frelinger	Platelets	2018
Function of protein kinase CK2 in thrombus formation E Ampofo, BM Schmitt, MW Laschke, MD Menger	Platelets	2018
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Functional Comparison of Induced Pluripotent Stem Cell- and Blood-Derived GPIIbIIIa Deficient Platelets M Orban, A Goedel, J Haas, K Sandrock-Lang, F Gärtner, CB Jung, B Zieger, E Parrotta, K Kurnik, D Sinnecker, G Wanner, KL Laugwitz, S Massberg, A Moretti, L Cheng	PloS one	2015
The Structure of a Full-length Membrane-embedded Integrin Bound to a Physiological Ligand A Dai, F Ye, DW Taylor, G Hu, MH Ginsberg, KA Taylor	The Journal of biological chemistry	2015
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Current concepts of platelet activation: possibilities for therapeutic modulation of heterotypic vs. homotypic aggregation G Passacquale, A Ferro	British Journal of Clinical Pharmacology	2011
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Novel function of human ADAM15 disintegrin-like domain and its derivatives in platelet aggregation OH Jeon, D Kim, YJ Choi, SH Kim, WS Choi, DS Kim	Thrombosis Research	2007
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Modeling of Biological Materials F Mollica, L Preziosi, KR Rajagopal		2007
Elevated fibrinogen fragment levels in uremic plasma inhibit platelet function and expression of glycoprotein IIb-IIIa UR Thekkedath, T Chirananthavat, JK Leypoldt, AK Cheung, SF Mohammad	American Journal of Hematology	2006
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Dissociation between fibrinogen and fibrin interaction with platelets in patients with different subtypes of Glanzmann's thrombasthenia: studies in an ex vivo perfusion chamber model P Hainaud, JP Brouland, P Andre, G Simoneau, CB Sollier, L Drouet, J Caen, S Bellucci	British Journal of Haematology	2002
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Antiplatelet Effect of 2-Chloro-3-(4-acetophenyl)-amino-1,4-naphthoquinone (NQ301): A Possible Mechanism through Inhibition of Intracellular Ca2+ Mobilization YH ZHANG, KH CHUNG, CK RYU, MH KO, MK LEE, YP YUN	Biological & Pharmaceutical Bulletin	2001
Discovery of an Orally Active Non-Peptide Fibrinogen Receptor Antagonist Based on the Hydantoin Scaffold HU Stilz, W Guba, B Jablonka, M Just, O Klingler, W König, V Wehner, G Zoller	Journal of Medicinal Chemistry	2001
Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen H Ni, CV Denis, S Subbarao, JL Degen, TN Sato, RO Hynes, DD Wagner	Journal of Clinical Investigation	2000
Necatoriasis: treatment and developmental therapeutics VS Georgiev	Expert Opinion on Investigational Drugs	2000
Platelets JN George	The Lancet	2000
Effect of a Micronized Purified Flavonoid Fraction on in Vivo Platelet Functions in the Rat L McGregor, M Bellangeon, E Chignier, L Lerond, C Rousselle, JL McGregor	Thrombosis Research	1999
The role of fibronectin in platelet adhesion to plasma preadsorbed polystyrene WB Tsai, TA Horbett	Journal of Biomaterials Science, Polymer Edition	1999
Cardiopulmonary Bypass Circuit Treated With Surface-Modifying Additives: A Clinical Evaluation of Blood Compatibility YJ PhD, PW PhD, AA Rijnsburger, JH BSc, WO PhD	The Annals of Thoracic Surgery	1998
Comparison of the Antithrombotic Effects of FK633, GPIIb/IIIa Antagonist, and Aspirin in a Guinea Pig Thrombosis Model T Aoki, D Cox, K Senzaki, J Seki, A Tanaka, H Takasugi, Y Motoyama	Thrombosis Research	1998
Purification and Molecular Cloning of a Platelet Aggregation Inhibitor from the Snake (Agkistrodon Halys Brevicaudus) Venom IC Kang, KH Chung, SJ Lee, Y Yun, HM Moon, DS Kim	Thrombosis Research	1998
6 Megakaryocytes and platelets in vascular disease B der Loo, JF Martin	Baillière's Clinical Haematology	1997
Thrombin-dependent calcium signalling in single human erythroleukaemia cells B Somasundaram, MJ Mason, MP Mahaut-Smith	The Journal of Physiology	1997
Interaction of Thrombin-activated Platelets with Extracellular Matrices (Fibronectin and Vitronectin): Comparison of the Activity of Arg-Gly-Asp-containing Venom Peptides and Monoclonal Antibodies Against Glycoprotein IIb/IIIa Complex JR Sheu, WC Ko, WC Hung, HC Peng, TF Huang	Journal of Pharmacy and Pharmacology	1997
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Triflavin Inhibits Platelet-Induced Vasoconstriction in De-endothelialized Aorta JR Sheu, MH Yen, WC Hung, YM Lee, CH Su, TF Huang	Arteriosclerosis, thrombosis, and vascular biology	1997
Textbook of Coronary Thrombosis and Thrombolysis RC Becker		1997
Thrombin-dependent calcium signalling in single human erythroleukaemia cells. Somasundaram B, Mason MJ, Mahaut-Smith MP	The Journal of Physiology	1997
Glanzmann thrombasthenia. Cooperation between sequence variants in cis during splice site selection Y Jin, HC Dietz, RA Montgomery, WR Bell, I McIntosh, B Coller, PF Bray	Journal of Clinical Investigation	1996
Binding of fibrinogen to platelet integrin αIIbβ3 in solution as monitored by tracer sedimentation equilibrium G Rivas, K Tangemann, AP Minton, J Engel	Journal of Molecular Recognition	1996
The anti-haemostatic strategies of the human hookworm Necator americanus BA Furmidge, LA Horn, DI Pritchard	Parasitology	1996
Initiation of Platelet Adhesion by Arrest onto Fibrinogen or Translocation on von Willebrand Factor B Savage, E Saldívar, ZM Ruggeri	Cell	1996
The anti-platelet and anti-thrombotic effects of FK633, a peptide-mimetic antagonist T Aoki, D Cox, K Senzaki, J Seki, A Tanaka, H Takasugi, Y Motoyama	Thrombosis Research	1996
Periodontal Management of Glanzmann's Thrombasthenia: Report of 3 Cases A Kantorci, I Cebeci, E Firatli, T Atamer, Ö Tuncer	Journal of Periodontology	1996
Substitutions of Proline 42 to Alanine and Methionine 46 to Asparagine around the RGD Domain of the Neurotoxin Dendroaspin Alter Its Preferential Antagonism to That Resembling the Disintegrin Elegantin X Lu, S Rahman, VV Kakkar, KS Authi	The Journal of biological chemistry	1996
Plasma Fibrinogen Inhibits Platelet Adhesion in Flowing Blood to Immobilized Fibrinogen SC Endenburg, L Lindeboom-Blokzijl, JJ Zwaginga, JJ Sixma, PG de Groot	Arteriosclerosis, thrombosis, and vascular biology	1996
Discovery of an Orally Active Non-Peptide Fibrinogen Receptor Antagonist HU Stilz, B Jablonka, M Just, J Knolle, EF Paulus, G Zoller	Journal of Medicinal Chemistry	1996
A chromatin binding site in the tail domain of nuclear lamins that interacts with core histones H Taniura, C Glass, L Gerace	The Journal of Cell Biology	1995
Interaction of Integrin αIIbβ3 with Multiple Fibrinogen Domains during Platelet Adhesion B Savage, E Bottini, ZM Ruggeri	The Journal of biological chemistry	1995
The pharmacology of the integrins D Cox, T Aoki, J Seki, Y Motoyama, K Yoshida	Medicinal Research Reviews	1994
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Integrins KO Simon, K Burridge	Integrins	1994
The megakaryocyte platelet system and vascular disease A S Brown, J F Martin	European Journal of Clinical Investigation	1994
Oral verapamil inhibits platelet thrombus formation in humans L L-Lacoste, JY Lam, J Hung, D Waters	Circulation	1994
Molecular and cellular biology of integrins DS Tuckwell, MJ Humphries	Critical Reviews in Oncology/Hematology	1993
The role of apoptosis (programmed cell death) in haemopoiesis and the immune system PD Allen, AC Newland, SA Bustin	Blood Reviews	1993
Synthetic RGD peptides derived from the adhesive domains of snake-venom proteins: evaluation as inhibitors of platelet aggregation X Lu, JJ Deadman, JA Williams, VV Kakkar, S Rahman	Biochemical Journal	1993
v-jun cooperates with v-erbB to transform the thrombocytic/megakaryocytic lineage M Garcia, J Samarut	Proceedings of the National Academy of Sciences	1993
Phagocyte recognition of cells undergoing apoptosis J Savill, V Fadok, P Henson, C Haslett	Immunology Today	1993
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The Role of Platelets in Blood-Biomaterial Interactions YF Missirlis, JL Wautier		1993
Cell Adhesion Molecules ME Hemler, E Mihich		1993
Endogenous platelet fibrinogen: its modulation after surface expression is related to size-selective access to and conformational changes in the bound fibrinogen HR Gralnick, SB Williams, L McKeown, B Shafer, GD Connaghan, K Hansmann, M Vail, L Magruder	British Journal of Haematology	1992
Effect of recombinant human granulocyte colony-stimulating factor (rhG-CSF) on circulating platelets HJ Avenarius, M Freund, J Deinhardt, H Poliwoda	Annals of Hematology	1992
Differences between platelet and microparticle glycoprotein IIb/IIIa S Nomura, M Suzuki, H Kido, K Yamaguchi, T Fukuroi, M Yanabu, T Soga, H Nagata, T Kokawa, K Yasunaga	Cytometry	1992
Binding of glycoprotein IIIa-derived peptide 217–231 to fibrinogen and von Willebrand factors and its inhibition by platelet glycoprotein IIb/IIIa complex JJ Cook, M Trybulec, EC Lasz, S Khan, S Niewiarowski	Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology	1992
Thrombolytic Therapy in Arterial Disease. I: Available Agents WS Hillis, JD Gemmill, PD Macintyre, B Bhargava		1992
Antithrombotic effects of a platelet fibrinogen receptor antagonist in a canine model of carotid artery thrombosis RN Willette, CF Sauermelch, R Rycyna, S Sarkar, GZ Feuerstein, AJ Nichols, EH Ohlstein	Stroke; a journal of cerebral circulation	1992
Examination of the platelet membrane glycoprotein IIb-IIIa complex and its interaction with fibrinogen and other ligands by electron microscopy JW Weisel, C Nagaswami, G Vilaire, JS Bennett	The Journal of biological chemistry	1992
The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stress Y Ikeda, M Handa, K Kawano, T Kamata, M Murata, Y Araki, H Anbo, Y Kawai, K Watanabe, I Itagaki	Journal of Clinical Investigation	1991
Monoclonal Antibodies to Platelet Glycoprotein IIb/IIIa as Antithrombotic Agents BS Coller, LE Scudder, J Beer, HK Gold, JD Folts, J Cavagnaro, R Jordan, C Wagner, J Iuliucci, D Knight, J Ghrayeb, C Smith, HF Weisman, H Berger	Annals of the New York Academy of Sciences	1991
Relationship between platelet volume and anti-platelet autoantibodies in idiopathic thrombocytopenic purpura T Kokawa, S Nomura, K Yasunaga	European Journal of Haematology	1991
Protein kinase C and cyclic AMP regulate reversible exposure of binding sites for fibrinogen on the glycoprotein IIB-IIIA complex of human platelets G Willigen, JW Akkerman	Biochemical Journal	1991
Assignment of disulphide bonds in human platelet GPIIIa. A disulphide pattern for the beta-subunits of the integrin family JJ Calvete, A Henschen, J González-Rodríguez	Biochemical Journal	1991
Characterization of a monoclonal antibody which is an activator of rabbit platelets LY Chau, JR Lin	Biochimica et Biophysica Acta (BBA) - General Subjects	1991
A modified Arg-Asp-Val (RDV) peptide derived during the synthesis of Arg-Glu-Asp-Val (REDV), a tetrapeptide derived from an alternatively spliced site in fibronectin, inhibits the binding of fibrinogen, fibronectin, von Willebrand factor and vitronectin to activated platelets CS Chen, IA Papayannopoulos, S Timmons, SH Chou, P Thiagarajan	Biochimica et Biophysica Acta (BBA) - General Subjects	1991
Changes in platelet function and reactivity induced by quinine in relation to quinine (drug) induced immune thrombocytopenia JM Connellan, S Deacon, PJ Thurlow	Thrombosis Research	1991
A colourimetric enzyme-linked sandwich assay for the detection of hunan platelets bound to a fibrinogen-coated surface CJ Nieman, R Kerry, PJ Coleman, A Taylor, J Jose, GF Pay	Thrombosis Research	1991
The antiplatelet effects of organic nitrates and related nitroso compounds in vitro and in vivo and their relevance to cardiovascular disorders JS Stamler, J Loscalzo	Journal of the American College of Cardiology	1991
Monoclonal Antibodies to Platelet Glycoprotein IIb/IIIa as Antithrombotic Agentsa BS Coller, LE Scudder, J Beer, HK Gold, JD Folts, J Cavagnaro, R Jordan, C Wagner, J Iuliucci, D Knight, J Ghrayeb, C Smith, HF Weisman, H Berger	Annals of the New York Academy of Sciences	1991
Megakaryocytes, Platelets, Macrophages, and Eosinophils JR Harris		1991
Molecular characterization of the human platelet integrin GPIIb/IIIa and its constituent glycoproteins GA Rivas, JA Aznrez, P Usobiaga, JL Saiz, J Gonzlez-Rodrguez	European Biophysics Journal	1991
Pharmacology of anistreplase S Sherry	Clinical Cardiology	1990
ADP Receptors in Platelets RW Colman	Annals of the New York Academy of Sciences	1990
Platelet glycoprotein IIb-IIIa protein antagonists from snake venoms: evidence for a family of platelet-aggregation inhibitors MS Dennis, WJ Henzel, RM Pitti, MT Lipari, MA Napier, TA Deisher, S Bunting, RA Lazarus	Proceedings of the National Academy of Sciences	1990
An Overview of Thrombolytic Agents J Loscalzo	Chest	1990
Secondary signals mediated by GPIIbIIIa in thrombin-activated platelets A Yamaguchi, K Tanoue, H Yamazaki	Biochimica et Biophysica Acta (BBA) - Molecular Cell Research	1990
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Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis J Savill, I Dransfield, N Hogg, C Haslett	Nature	1990
Fibrinogen, Thrombosis, Coagulation, and Fibrinolysis CY Liu, S Chien		1990
A conformation-dependent epitope of human platelet glycoprotein IIIa WC Kouns, CD Wall, MM White, CF Fox, LK Jennings	The Journal of biological chemistry	1990
Decorsin. A potent glycoprotein IIb-IIIa antagonist and platelet aggregation inhibitor from the leech Macrobdella decora JL Seymour, WJ Henzel, B Nevins, JT Stults, RA Lazarus	The Journal of biological chemistry	1990
Interaction of integrins alpha v beta 3 and glycoprotein IIb-IIIa with fibrinogen. Differential peptide recognition accounts for distinct binding sites JW Smith, ZM Ruggeri, TJ Kunicki, DA Cheresh	The Journal of biological chemistry	1990
Purification and functional characterization of integrin alpha v beta 5. An adhesion receptor for vitronectin JW Smith, DJ Vestal, SV Irwin, TA Burke, DA Cheresh	The Journal of biological chemistry	1990
Fibrinogen-independent platelet adhesion and thrombus formation on subendothelium mediated by glycoprotein IIb-IIIa complex at high shear rate HJ Weiss, J Hawiger, ZM Ruggeri, VT Turitto, P Thiagarajan, T Hoffmann	Journal of Clinical Investigation	1989
Recognition of distinct adhesive sites on fibrinogen by related integrins on platelets and endothelial cells DA Cheresh, SA Berliner, V Vicente, ZM Ruggeri	Cell	1989
Die megakaryozytäre Myelose — Klinik, Morphologie und Plättchenfunktion A Hochhaus, D Höche, K Mindner, G Ostermann, M Meyer	Klinische Wochenschrift	1989
Activation-dependent redistribution of the adhesion plaque protein, talin, in intact human platelets MC Beckerle, DE Miller, ME Bertagnolli, SJ Locke	The Journal of Cell Biology	1989
Effects of Ticlopidine and Indobufen on Platelet Aggregation Induced by A23187 and Adrenaline in the Presence of Different Anticoagulants C Cimminiello, M Milani, T Uberti, G Arpaia, G Bonfardeci	J INT MED RES	1989
Isolation and characterization of platelet glycoprotein IV (CD36) NN Tandon, RH Lipsky, WH Burgess, GA Jamieson	The Journal of biological chemistry	1989
Ligand Inhibition of the Platelet Glycoprotein IIb-IIIa Complex Function as a Calcium Channel in Liposomes ME Rybak, LA Renzulli	The Journal of biological chemistry	1989
Effects of monoclonal antibodies against the platelet glycoprotein IIb/IIIa complex on thrombosis and hemostasis in the baboon SR Hanson, FI Pareti, ZM Ruggeri, UM Marzec, TJ Kunicki, RR Montgomery, TS Zimmerman, LA Harker	Journal of Clinical Investigation	1988
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Human Fibrinogen HA Scheraga, JA Shafer, DL Higgins	Critical Reviews in Clinical Laboratory Sciences	1988
Fibrin(ogen) peptide B.beta. 15-42 inhibits platelet aggregation and fibrinogen binding to activated platelets CS Chen, SH Chou, P Thiagarajan	Biochemistry	1988
Endothelial Cell Biology in Health and Disease N Simionescu, M Simionescu		1988
Platelet-Vessel Wall Interactions RM Pittilo, SJ Machin		1988
Exposure of binding sites for vitronectin on platelets following stimulation P Thiagarajan, KL Kelly	The Journal of biological chemistry	1988
Generation and characterization of peptide-specific antibodies that inhibit von Willebrand factor binding to glycoprotein IIb-IIIa without interacting with other adhesive molecules. Selectivity is conferred by Pro1743 and other amino acid residues adjacent to the sequence Arg1744-Gly1745-Asp1746 S Berliner, K Niiya, JR Roberts, RA Houghten, ZM Ruggeri	The Journal of biological chemistry	1988
Fibrin induces release of von Willebrand factor from endothelial cells JA Ribes, CW Francis, DD Wagner	Journal of Clinical Investigation	1987
A variant of Glanzmann's thrombasthenia with abnormal glycoprotein IIb-IIIa complexes in the platelet membrane AT Nurden, JP Rosa, D Fournier, C Legrand, D Didry, A Parquet, D Pidard	Journal of Clinical Investigation	1987
Isolation of the thrombospondin membrane receptor AS Asch, J Barnwell, RL Silverstein, RL Nachman	Journal of Clinical Investigation	1987
On the association of the platelet-specific alloantigen, Pena, with glycoprotein IIIa. Evidence for heterogeneity of glycoprotein IIIa K Furihata, DJ Nugent, A Bissonette, RH Aster, TJ Kunicki	Journal of Clinical Investigation	1987
Macromolecules That Link Platelets following Vessel Wall Injury J Hawiger	Annals of the New York Academy of Sciences	1987
Factor XIII: a marker of mono- and megakaryocytopoiesis R Ádány, A Kiss, L Muszbek	British Journal of Haematology	1987
β2-glycoprotein-I (apo-H) inhibits the release reaction of human platelets during ADP-induced aggregation J Nimpf, H Wurm, GM Kostner	Atherosclerosis	1987
Experimental models for evaluating antithrombotic therapies in replantation microsurgery BC Cooley, JS Gould	Microsurgery	1987
The platelet glycoprotein IIb/IIIa-like protein in human endothelial cells promotes adhesion but not initial attachment to extracellular matrix CS Chen, P Thiagarajan, SM Schwartz, JM Harlan, RL Heimark	The Journal of Cell Biology	1987
A human erythroleukemia cell line synthesizes a functionally active glycoprotein IIb-IIIa complex capable of binding fibrinogen P Thiagarajan, SS Shapiro, L Sweterlitsch, S McCord	Biochimica et Biophysica Acta (BBA) - General Subjects	1987
Quantitation and characterization of human platelet glycoprotein IIIa by radioimmunoassay CS Cierniewski, S Niewiarowski, D Hershock, B Rucinski, AH Schmaier	Biochimica et Biophysica Acta (BBA) - General Subjects	1987
Effects of EDTA on the membrane glycoproteins IIB-IIIa complex — analysis using flow cytometry S Nomura, H Nagata, K Oda, T Kokawa, K Yasunaga	Thrombosis Research	1987
The N-dsk γ-chain binds to immunoprecipitated GP IIb-IIIa LI Thorsen, B Hessel, F Brosstad, G Gogstad, NO Solum	Thrombosis Research	1987
Ca2+ influx mediated through the GPIIb/IIIa complex during platelet activation A Yamaguchi, N Yamamoto, H Kitagawa, K Tanoue, H Yamazaki	FEBS Letters	1987
Evidence that arginyl-glycyl-aspartate peptides and fibrinogen gamma chain peptides share a common binding site on platelets SC Lam, EF Plow, MA Smith, A Andrieux, JJ Ryckwaert, G Marguerie, MH Ginsberg	The Journal of biological chemistry	1987
A myeloma paraprotein with specificity for platelet glycoprotein IIIa in a patient with a fatal bleeding disorder G DiMinno, F Coraggio, AM Cerbone, AM Capitanio, C Manzo, M Spina, P Scarpato, GM Dattoli, PL Mattioli, M Mancini	Journal of Clinical Investigation	1986
Exposure of fibrinogen receptors in human platelets by surface proteolysis with elastase E Kornecki, YH Ehrlich, DD de Mars, RH Lenox	Journal of Clinical Investigation	1986
Platelet activation in normo- and hyperlipoproteinemias J Nimpf, H Wurm, GM Kostner, T Kenner	Basic Research in Cardiology	1986
Binding of 125I-labelled fibrin(ogen) fragments to platelets and to immunoprecipitated glycoprotein IIb-IIIa complex LI Thorsen, F Brosstad, G Gogstad, K Sletten, NO Solum	Thrombosis Research	1986
Increased binding to ADP-stimulated platelets and aggregation effect of the dysfibrinogen Oslo I as compared with normal fibrinogen LI Thorsen, F Brosstad, NO Solum, H Stormorken	Scandinavian Journal of Haematology	1986
Identification of two distinct regions within the binding sites for fibrinogen and fibronectin on the IIb-IIIa human platelet membrane glycoprotein complex by monoclonal antibodies P2 and P4 JL McGREGOR, L McGREGOR, AS BAUER, B CATIMEL, J BROCHIER, M DECHAVANNE, KJ CLEMETSON	European Journal of Biochemistry	1986
Immunologic and biochemical characterization of homozygous and heterozygous Glanzmann thrombasthenia in the Iraqi-Jewish and Arab populations of Israel: comparison of techniques for carrier detection BS Coller, U Seligsohn, A Zivelin, E Zwang, A Lusky, M Modan	British Journal of Haematology	1986
A role for glycoprotein IIb-IIIa complex in the binding of IgE to human platelets and platelet IgE-dependent cytotoxic functions JC Ameisen, M Joseph, JP Caen, JP Kusnierz, M Capron, B Boizard, J Wautier, S Levy-Toledano, H Vorng, A Capron	British Journal of Haematology	1986
The role of platelet membrane glycoproteins Ib and IIb-IIIa in platelet adherence to human artery subendothelium KS Sakariassen, PF Nievelstein, BS Coller, JJ Sixma	British Journal of Haematology	1986
Changes in platelet β-thromboglobulin, fibrinogen, albumin, 5-hydroxytryptamine, ATP, and ADP during and after surgery with extracorporeal circulation in man D Mezzano, E Aranda, J Urzúa, G Lema, J Habash, MJ Irarrázabal, J Pereira	American Journal of Hematology	1986
Glycoprotein Ib beta is the only phosphorylated major membrane glycoprotein in human platelets B Wyler, D Bienz, KJ Clemetson, EF Luscher	Biochemical Journal	1986
Biogenesis of the platelet receptor for fibrinogen: evidence for separate precursors for glycoproteins IIb and IIIa PF Bray, JP Rosa, VR Lingappa, YW Kan, RP McEver, MA Shuman	Proceedings of the National Academy of Sciences	1986
A genomic clone encoding the alpha chain of the OKM1, LFA-1, and platelet glycoprotein IIb-IIIa molecules LJ Cosgrove, MS Sandrin, P Rajasekariah, IF McKenzie	Proceedings of the National Academy of Sciences	1986
Activation affects access to the platelet receptor for adhesive glycoproteins BS Coller	The Journal of Cell Biology	1986
Identification of receptors for fibrinogen and von willebrand factor mediating aggregation in guinea pig platelets JM Kupinski, JL Miller	Thrombosis Research	1986
Two-dimensional electrophoretic studies of platelets from dogs affected with basset hound hereditary thrombopathy: A thrombasthenia-like aggregation defect WR Patterson, TJ Kunicki, TG Bell	Thrombosis Research	1986
Biochemistry of Platelets GJ Roth	Biochemistry of Platelets	1986
Increased fibrinogen binding to platelets from patients with familial hypercholesterolemia G DiMinno, MJ Silver, AM Cerbone, A Rainone, A Postiglione, M Mancini	Arteriosclerosis (Dallas, Tex.)	1986
Thrombospondin: a versatile multifunctional glycoprotein RL Silverstein, LL Leung, RL Nachman	Arteriosclerosis (Dallas, Tex.)	1986
Imaging thrombus with radiolabelled monoclonal antibody to platelets AM Peters, JP Lavender, SG Needham, I Loutfi, D Snook, AA Epenetos, P Lumley, RJ Keery, N Hogg	BMJ : British Medical Journal	1986
Crossed immunoelectrophoresis of human platelet membranes. Effect of charge on association and dissociation of the glycoprotein GPIIb-GPIIIa membrane complex S Karpatkin, R Ferziger, D Dorfman	The Journal of biological chemistry	1986
Resting platelets contain a substantial centrally located pool of glycoprotein IIb-IIIa complex which may be accessible to some but not other extracellular proteins VL Woods, LE Wolff, DM Keller	The Journal of biological chemistry	1986
Fibronectin-binding properties of the purified platelet glycoprotein IIb-IIIa complex LV Parise, DR Phillips	The Journal of biological chemistry	1986
Functionally thrombasthenic state in normal platelets following the administration of ticlopidine GD Minno, AM Cerbone, PL Mattioli, S Turco, C Iovine, M Mancini	Journal of Clinical Investigation	1985
Human neutrophil elastase modulates platelet function by limited proteolysis of membrane glycoproteins MS Brower, RI Levin, K Garry	Journal of Clinical Investigation	1985
A monoclonal antibody to human platelet glycoprotein IIIa detects a related protein in cultured human endothelial cells P Thiagarajan, SS Shapiro, E Levine, L DeMarco, A Yalcin	Journal of Clinical Investigation	1985
Independent modulation of von Willebrand factor and fibrinogen binding to the platelet membrane glycoprotein IIb/IIIa complex as demonstrated by monoclonal antibody VT Lombardo, E Hodson, JR Roberts, TJ Kunicki, TS Zimmerman, ZM Ruggeri	Journal of Clinical Investigation	1985
Complete correction of Glanzmann's thrombasthenia by allogeneic bone-marrow transplantation S Bellucci, A Devergie, E Gluckman, G Tobelem, P Lethielleux, M Benbunan, G Schaison, M Boiron	British Journal of Haematology	1985
Identification and characterization of fragments of major glycoproteins from platelet membrane after chymotrypsin treatment JL McGREGOR, P CLEZARDIN, E JAMES, L McGREGOR, M DECHAVANNE, KJ CLEMETSON	European Journal of Biochemistry	1985
Interaction of fibronectin with its receptor on platelets JM Gardner, RO Hynes	Cell	1985
A monoclonal antibody against human thrombospondin inhibits platelet aggregation VM Dixit, DM Haverstick, KM O'Rourke, SW Hennessy, GA Grant, SA Santoro, WA Frazier	Proceedings of the National Academy of Sciences	1985
Human megakaryocytes. V. Changes in the phenotypic profile of differentiating megakaryocytes RB Levene, JM Lamaziere, HE Broxmeyer, L Lu, EM Rabellino	Journal of Experimental Medicine	1985
Fibrinogen fragment D is a recognition site for release-related platelet aggregation G Agam, O Shohat, A Livne	Thrombosis Research	1985
Abnormal release of storage pool adenine nucleotides from platelets of dogs affected with basset hound hereditary thrombopathy WR Patterson, GA Padgett, TG Bell	Thrombosis Research	1985
Membrane fluidity and platelet fibrinogen receptor exposure by proteolytic enzymes E Simons, JC Whitin, TA Morinelli, GJ Stewart, S Niewiarowski	Thrombosis Research	1985
Monoclonal antibodies against human platelet membrane glycoproteins IIb-IIIa II. Different effects on platelet function D Heinrich, T Scharf, S Santoso, KJ Clemetson, C Mueller-Eckhardt	Thrombosis Research	1985
Immunodetection with streptavidin-acid phosphatase complex on Western blots MS Brower, CL Brakel, K Garry	Analytical Biochemistry	1985
The Platelets SM Stahl	The Platelets	1985
Examination of irreversible platelet-fibrinogen interactions EI Peerschke, JA Wainer	American journal of physiology. Cell physiology	1985
Lysine binding to activated human platelets and its similarity to fibrinogen binding G Agam, R Luria, O Shohat, A Dvilansky, U Seligsohn, A Livne	Biochimica et Biophysica Acta (BBA) - Molecular Cell Research	1985
Platelet activation MB Zucker, VT Nachmias	Arteriosclerosis (Dallas, Tex.)	1985
Extracellular matrices and cell adhesion E Ruoslahti, EG Hayman, MD Pierschbacher	Arteriosclerosis (Dallas, Tex.)	1985
Mechanisms of Stimulus—Response Coupling in Platelets J Westwick, MF Scully, DE MacIntyre, VV Kakkar		1985
Platelet Membrane Glycoproteins JN George, AT Nurden, DR Phillips		1985
Platelet membrane glycoprotein IIb-IIIa complex incorporated into phospholipid vesicles. Preparation and morphology LV Parise, DR Phillips	The Journal of biological chemistry	1985
Reconstitution of the purified platelet fibrinogen receptor. Fibrinogen binding properties of the glycoprotein IIb-IIIa complex LV Parise, DR Phillips	The Journal of biological chemistry	1985
Effect of calcium on the stability of the platelet membrane glycoprotein IIb-IIIa complex LF Brass, SJ Shattil, TJ Kunicki, JS Bennett	The Journal of biological chemistry	1985
Structure of human platelet membrane glycoproteins IIb and IIIa as determined by electron microscopy NA Carrell, LA Fitzgerald, B Steiner, HP Erickson, DR Phillips	The Journal of biological chemistry	1985
Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation SJ Shattil, JA Hoxie, M Cunningham, LF Brass	The Journal of biological chemistry	1985
Retention of the glycoprotein IIb-IIIa complex in the isolated platelet cytoskeleton. Effects of separable assembly of platelet pseudopodal and contractile cytoskeletons ME Wheeler, AC Cox, RC Carroll	Journal of Clinical Investigation	1984
Role of thrombospondin in platelet aggregation LL Leung	Journal of Clinical Investigation	1984
The platelet-fibrinogen interaction. Evidence for proximity of the Aalpha chain of fibrinogen to platelet membrane glycoproteins IIb/III GA MARGUERIE, N THOMAS-MAISON, MH GINSBERG, EF PLOW	European Journal of Biochemistry	1984
Platelet aggregation: its relation with ADP-induced fibrinogen binding to platelets and ADP-related membrane enzyme activities C LEGRAND, V DUBERNARD, J CAEN	European Journal of Biochemistry	1984
ADP-dependent common receptor mechanism for binding of von Willebrand factor and fibrinogen to human platelets S Timmons, M Kloczewiak, J Hawiger	Proceedings of the National Academy of Sciences	1984
Expression of platelet membrane glycoproteins and alpha-granule proteins by a human erythroleukemia cell line (HEL) A Tabilio, JP Rosa, U Testa, N Kieffer, AT Nurden, MC Canizo, J Breton-Gorius, W Vainchenker	The EMBO Journal	1984
Redistribution of the fibrinogen receptor of human platelets after surface activation JC Loftus, RM Albrecht	The Journal of Cell Biology	1984
Comparison of platelet fibrinogen receptors on intact and proteolytically-treated platelets by use of an antiglycoprotein IIIa monoclonal antibody (MA 123) E Kornecki, H Lee, F Merlin, D Hershock, GP Tuszynski, S Niewiarowski	Thrombosis Research	1984
Comparative study of the major glycoproteins of the plasma membrane and secretory granule membranes of porcine platelets S Grinstein, W Furuya	Comparative Biochemistry and Physiology Part B: Comparative Biochemistry	1984
Molecular Defects in Interactions of Platelets with the Vessel Wall JN George, AT Nurden, DR Phillips	New England Journal of Medicine	1984
Interaction of specific platelet membrane proteins with collagen: evidence from chemical crosslinking NJ Kotite, JV Staros, LW Cunningham	Biochemistry	1984
Association of fibrin with the platelet cytoskeleton GP Tuszynski, E Kornecki, C Cierniewski, LC Knight, A Koshy, S Srivastava, S Niewiarowski, PN Walsh	The Journal of biological chemistry	1984
A monoclonal antibody to a membrane glycoprotein binds only to activated platelets RP McEver, MN Martin	The Journal of biological chemistry	1984
Complex formation of platelet membrane glycoproteins IIb and IIIa with the fibrinogen D domain RL Nachman, LL Leung, M Kloczewiak, J Hawiger	The Journal of biological chemistry	1984
Characteristics of an ADP receptor mediating platelet activation RW Colman, WR Figures	Molecular and Cellular Biochemistry	1984
A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa BS Coller, EI Peerschke, LE Scudder, CA Sullivan	Journal of Clinical Investigation	1983
FIBRINOGEN INTERACTION WITH PLATELET RECEPTORS? S Niewiarowski, E Kornecki, AZ Budzynski, TA Morinelli, GP Tuszynski	Annals of the New York Academy of Sciences	1983
Heparin-binding platelet proteins demonstrated by crossed affinity immunoelectrophoresis GO Gogstad, NO Solum, MB Krutnes	British Journal of Haematology	1983
The influence of amines on various platelet responses DS Houston, JM Gerrard, J McCrea, S Glover, AM Butler	Biochimica et Biophysica Acta (BBA) - Biomembranes	1983
Monoclonal antibodies against human platelet glycoprotein IIIa PA Tetteroo, PM Lansdorp, OC Leeksma, AE von Borne	British Journal of Haematology	1983
Calcium-Binding Proteins from Human Platelets. A study Using Crossed Immunoelectrophoresis and 45Ca2+ GO GOGSTAD, MB KRUTNES, NO SOLUM	European Journal of Biochemistry	1983
Inhibition of fibrinogen binding to stimulated human platelets by a monoclonal antibody JS Bennett, JA Hoxie, SF Leitman, G Vilaire, DB Cines	Proceedings of the National Academy of Sciences	1983
Monocytes and platelets share the glycoproteins IIb and IIIa that are absent from both cells in Glanzmann's thrombasthenia type I G Gogstad, O Hetland, NO Solum, H Prydz	Biochemical Journal	1983
A new bleeding disorder: Lack of platelet aggregatory response to adrenalin and lack of secondary aggregation to ADP and platelet activating factor (PAF) H Stormorken, G Gogstad, NO Solum	Thrombosis Research	1983
Glycoprotein IIb-IIIa complex in platelets of patients and heterozygotes of Glanzmann's thrombasthenia FH Herrmann, M Meyer, GO Gogstad, NO Solum	Thrombosis Research	1983
Properties of PAF-acether-induced platelet aggregation and secretion. Studies in gel-filtered human platelets E Kloprogge, GH Haas, G Gorter, JW Akkerman	Thrombosis Research	1983
Inhibition of fibrinogen receptor-mediated platelet aggregation by heterologous anti-human platelet membrane antibody. Significance of an Mr = 66,000 protein derived from glycoprotein IIIa E Kornecki, GP Tuszynski, S Niewiarowski	The Journal of biological chemistry	1983
Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets D Pidard, RR Montgomery, JS Bennett, TJ Kunicki	The Journal of biological chemistry	1983
Identification of two structurally and functionally distinct sites on human platelet membrane glycoprotein IIb-IIIa using monoclonal antibodies RP McEver, EM Bennett, MN Martin	The Journal of biological chemistry	1983
Reversal of thrombin-induced myosin phosphorylation and the assembly of cytoskeletal structures in platelets by the adenylate cyclase stimulants prostaglandin D2 and forskolin MB Feinstein, JJ Egan, EE Opas	The Journal of biological chemistry	1983
Complex formation of platelet thrombospondin with fibrinogen LL Leung, RL Nachman	Journal of Clinical Investigation	1982
Dissociation of the glycoprotein IIb-IIIa complex in isolated human platelet membranes GO Gogstad, I Hagen, MB Krutnes, NO Solum	Biochimica et Biophysica Acta (BBA) - Biomembranes	1982
Glanzmann thrombasthenia: deficient binding of von Willebrand factor to thrombin-stimulated platelets ZM Ruggeri, R Bader, L Marco	Proceedings of the National Academy of Sciences	1982
Protides of the Biological Fluids PA Small, RH Waldman	Protides of the Biological Fluids	1969
Blut und Blutkrankheiten L Heilmeyer, K Betke, KG von Boroviczény, D Busch, E Grundmann, H Heimpel, G Hoffmann, W Hunstein, W Keiderling, M Matthes, H Merker, W Müller, P Pfannenstiel		1968

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