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Citations to this article

Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose.
R N Bergman, … , L S Phillips, C Cobelli
R N Bergman, … , L S Phillips, C Cobelli
Published December 1, 1981
Citation Information: J Clin Invest. 1981;68(6):1456-1467. https://doi.org/10.1172/JCI110398.
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Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose.

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Abstract

The quantitative contributions of pancreatic responsiveness and insulin sensitivity to glucose tolerance were measured using the "minimal modeling technique" in 18 lean and obese subjects (88-206% ideal body wt). The individual contributions of insulin secretion and action were measured by interpreting the dynamics of plasma glucose and insulin during the intravenous glucose tolerance test in terms of two mathematical models. One, the insulin kinetics model, yields parameters of first-phase (phi 1) and second-phase (phi 2) responsivity of the beta-cells to glucose. The other glucose kinetics model yields the insulin sensitivity parameters, SI. Lean and obese subjects were subdivided into good (KG greater than 1.5) and lower (KG less than 1.5) glucose tolerance groups. The etiology of lower glucose tolerance was entirely different in lean and obese subjects. Lean, lower tolerance was related to pancreatic insufficiency (phi 2 77% lower than in good tolerance controls [P less than 0.03]), but insulin sensitivity was normal (P greater than 0.5). In contrast, obese lower tolerance was entirely due to insulin resistance (SI diminished 60% [P less than 0.01]); pancreatic responsiveness was not different from lean, good tolerance controls (phi 1: P greater than 0.06; phi 2: P greater than 0.40). Subjects (regardless of weight) could be segregated into good and lower tolerance by the product of second-phase beta-cell responsivity and insulin sensitivity (phi 2 . SI). Thus, these two factors were primarily responsible for overall determination of glucose tolerance. The effect of phi 1 was to modulate the KG value within those groups whose overall tolerance was determined by phi 2 . SI. This phi 1 modulating influence was more pronounced among insulin sensitive (phi 1 vs. KG, r = 0.79) than insulin resistant (obese, low tolerance; phi 1 vs. KG, r = 0.91) subjects. This study demonstrates the feasibility of the minimal model technique to determine the etiology of impaired glucose tolerance.

Authors

R N Bergman, L S Phillips, C Cobelli

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Simulation of physical activities effect and treatment exogenous insulin for managing plasma glucose concentration in type 1 diabetes mellitus
A Kartono, M Sari, ST Wahyudi
Journal of physics. Conference series 2020
Robust LPV control design for blood glucose regulation considering daily life factors
A Mirzaee, M Dehghani, M Mohammadi
Biomedical Signal Processing and Control 2020
Global Sensitivity Analysis on the Bergman Minimal Model
S Nandi, T Singh
IFAC-PapersOnLine 2020
Stable impulsive zone model predictive control for type 1 diabetic patients based on a long‐term model
AH González, PS Rivadeneira, A Ferramosca, N Magdelaine, CH Moog
Optimal Control Applications and Methods 2020
On the way to strict glycemic control for hemodialysis patients
J Klespitz, L Kovacs
2020
Do components of adult height predict body composition and cardiometabolic risk in a young adult South Asian Indian population? Findings from a hospital-based cohort study in Pune, India: Pune Children’s Study
K Kumaran, SM Joshi, CD Gravio, H Lubree, C Joglekar, D Bhat, A Kinare, A Bavdekar, S Bhave, A Pandit, C Osmond, C Yajnik, C Fall
BMJ Open 2020
Blood glucose regulation and control of insulin and glucagon infusion using single model predictive control for type 1 diabetes mellitus.
Crecil Dias C, Kamath S, Vidyasagar S
IET Systems Biology 2020
Birth weight, childhood and adolescent growth and diabetes risk factors in 21-year old Asian Indians: The Pune Children’s Study
Kumaran K, Lubree H, Bhat DS, Joshi S, Joglekar C, Yajnik P, Bhave S, Pandit A, Fall CH, Yajnik CS
Journal of developmental origins of health and disease 2020
Augmented insulin secretory response in early pregnancy
CE Powe, LP Presley, JJ Locascio, PM Catalano
Diabetologia 2019
Glucoregulatory responses to hypothalamic preoptic area cooling
K Muta, ME Matsen, NK Acharya, D Stefanovski, RN Bergman, MW Schwartz, GJ Morton
Brain Research 2019
Changing the Concept of Type 2 Diabetes: Beta Cell Workload Hypothesis Revisited
Y Saisho
Endocrine, metabolic & immune disorders drug targets 2019
Lower Insulin Clearance Parallels a Reduced Insulin Sensitivity in Obese Youths and Is Associated With a Decline in β-Cell Function Over Time
A Galderisi, D Polidori, R Weiss, C Giannini, B Pierpont, D Tricò, S Caprio
Diabetes 2019
Consumer-Driven Technologies in Healthcare: Breakthroughs in Research and Practice
IR Association
2019
An adaptive backstepping based non-linear controller for artificial pancreas in type 1 diabetes patients
I Ahmad, F Munir, MF Munir
Biomedical Signal Processing and Control 2019
Consistency of compact and extended models of glucose-insulin homeostasis: The role of variable pancreatic reserve
AD Gaetano, C Gaz, S Panunzi, N Suksomboon
PloS one 2019
Optimal regulation of blood glucose level in Type I diabetes using insulin and glucagon
A Shirin, FD Rossa, I Klickstein, J Russell, F Sorrentino, A Singh
PloS one 2019
Heart Rate, Autonomic Function, and Future Changes in Glucose Metabolism in Individuals Without Diabetes: The Whitehall II Cohort Study
CS Hansen, K Færch, ME Jørgensen, M Malik, DR Witte, EJ Brunner, AG Tabák, M Kivimäki, D Vistisen
Diabetes care 2019
Central role of the β-cell in driving regression of diabetes after liver transplantation in cirrhotic patients
V Grancini, M Trombetta, ME Lunati, ML Boselli, S Gatti, MF Donato, E Palmieri, V Resi, G Pugliese, RC Bonadonna, E Orsi
Journal of Hepatology 2019
Single-centre, triple-blinded, randomised, 1-year, parallel-group, superiority study to compare the effects of Roux-en-Y gastric bypass and sleeve gastrectomy on remission of type 2 diabetes and β-cell function in subjects with morbid obesity: a protocol for the Obesity s urg e ry in Tøns berg ( O seberg) study
H Borgeraas, J Hjelmesæth, KI Birkeland, F Fatima, JO Grimnes, HL Gulseth, E Halvorsen, JK Hertel, TO Hillestad, LK Johnson, TI Karlsen, RL Kolotkin, NP Kvan, M Lindberg, J Lorentzen, N Nordstrand, R Sandbu, KA Seeberg, B Seip, M Svanevik, TG Valderhaug, D Hofsø
BMJ Open 2019
Hypothesis: Role of Reduced Hepatic Insulin Clearance in the Pathogenesis of Type 2 Diabetes
RN Bergman, F Piccinini, M Kabir, CM Kolka, M Ader
Diabetes 2019
Macrophage‐Derived microRNA‐155 Increases in Obesity and Influences Adipocyte Metabolism by Targeting Peroxisome Proliferator‐Activated Receptor Gamma
JB Tryggestad, AM Teague, DP Sparling, S Jiang, SD Chernausek
Obesity 2019
Mathematical model for diabetes in fuzzy environment with stability analysis
A Mahata, SP Mondal, S Alam, A Chakraborty, SK Dey
J INTELL FUZZY SYST 2019
Insulin Resistance as a Result of Body Condition Categorized as Thin, Moderate, and Obese in Domesticated U.S. Donkeys (Equus asinus)
A Pritchard, B Nielsen, A McLean, C Robison, M Yokoyama, S Hengemuehle, S Bailey, P Harris
Journal of Equine Veterinary Science 2019
Glucose–insulin stabilization in type-1 diabetic patient: A uniform exact differentiator–based robust integral sliding mode control approach
W Alam, Q Khan, RA Riaz, R Akmeliawati
International Journal of Distributed Sensor Networks 2019
Robust multi-objective blood glucose control in Type-1 diabetic patient
S Mandal, A Sutradhar
IET Systems Biology 2019
Translational Research Methods in Diabetes, Obesity, and Nonalcoholic Fatty Liver Disease: A Focus on Early Phase Clinical Drug Development
AJ Krentz, C Weyer, M Hompesch
2019
Biotechnology: Concepts, Methodologies, Tools, and Applications
IR Association
2019
Sliding-mode disturbance observers for an artificial pancreas without meal announcement
I Sala-Mira, JL Díez, B Ricarte, J Bondia
Journal of Process Control 2019
Handling Parameter Variations during the Treatment of Type 1 Diabetes Mellitus: In Silico Results
MF Tamayo, MA Alvarez, PS Rivadeneira
Mathematical Problems in Engineering 2019
Modest changes to glycemic regulation are sufficient to maintain glucose flux in healthy humans following overfeeding with a habitual macronutrient composition
DJ Morrison, GM Kowalski, CR Bruce, GD Wadley
American journal of physiology. Endocrinology and metabolism 2019
Association of ghrelin dynamics with beta cell function in Japanese subjects with normal glucose tolerance
N Murai, N Saito, E Kodama, T Iida, K Mikura, H Imai, M Kaji, M Hashizume, Y Kigawa, G Koizumi, R Tadokoro, C Sugisawa, K Endo, T Iizaka, R Saiki, F Otsuka, I Shun, S Nagasaka
Clinical Endocrinology 2019
Construction of pancreas–muscle–liver microphysiological system (MPS) for reproducing glucose metabolism
DW Lee, SH Lee, N Choi, JH Sung
Biotechnology and Bioengineering 2019
Longitudinal changes in glucose metabolism in women with gestational diabetes, from late pregnancy to the postpartum period
TP Waters, SY Kim, AJ Sharma, P Schnellinger, JK Bobo, RT Woodruff, LA Cubbins, M Haghiac, J Minium, L Presley, H Wolfe, SH Mouzon, W Adams, PM Catalano
Diabetologia 2019
Simulation software for assessment of nonlinear and adaptive multivariable control algorithms: Glucose–insulin dynamics in Type 1 diabetes
M Rashid, S Samadi, M Sevil, I Hajizadeh, P Kolodziej, N Hobbs, Z Maloney, R Brandt, J Feng, M Park, L Quinn, A Cinar
Computers & chemical engineering 2019
Dual glucagon‐like peptide‐1 receptor/glucagon receptor agonist SAR425899 improves beta‐cell function in type 2 diabetes
R Visentin, M Schiavon, B Göbel, M Riz, C Cobelli, T Klabunde, CD Man
Diabetes, obesity & metabolism 2019
TTP399: an investigational liver-selective glucokinase (GK) activator as a potential treatment for type 2 diabetes
A Egan, A Vella
Expert Opinion on Investigational Drugs 2019
1,5-Anhydroglucitol × glycated hemoglobin A1c/100 as a potential biomarker for islet β-cell function among patients with type 2 diabetes
H Su, X Ma, Y Shen, X He, L Ying, W Zhu, Y Wang, Y Bao, J Zhou
Acta Diabetologica 2019
T-S Fuzzy Control for Blood Glucose Regulation in Type-1 Diabetes
J Pan, Z Kang, W Zhang, B Zhang, H Shi
2019
Fuzzy model-based controller for blood glucose control in type 1 diabetes: An LMI approach
B Farahmand, M Dehghani, N Vafamand
Biomedical Signal Processing and Control 2019
Model Predictive Control of the Blood Glucose Concentration for Critically Ill Patients in Intensive Care Units
AT Reenberg, D Boiroux, TK Ritschel, JB Jorgensen
2019
A nonlinear time-delay realization for gastroparesis in patients with diabetes
C Califano, E Scharbarg, N Magdelaine, CH Moog
Annual Reviews in Control 2019
Open-source low-cost Hardware-in-the-loop simulation platform for testing control strategies for artificial pancreas research
LF Quesada, JD Rojas, O Arrieta, R Vilanova
IFAC-PapersOnLine 2019
Predictive Active Disturbance Rejection Control for Insulin Infusion in Patients with T1DM
JJ Carreño-Zagarra, R Villamizar, JC Moreno, JL Guzmán
IFAC-PapersOnLine 2019
A review on control-relevant glucose–insulin dynamics models and regulation strategies
S Bhonsle, S Saxena
P I MECH ENG I-J SYS 2019
Model Predictive Control of Blood Glucose for Type 1 Diabetic Rats in a Cyber-Physical System
HS Ko, R Balouchzadeh, G Uzun, HF Lee, S Park, G Kwon
2019
The evolution of control algorithms in artificial pancreas: A historical perspective
G Quiroz
Annual Reviews in Control 2019
Robust multi-objective blood glucose control in Type-1 diabetic patient.
Mandal S, Sutradhar A
IET Systems Biology 2019
Insulin signaling in the whole spectrum of GH deficiency
Garmes HM, Castillo AR
Archives of Endocrinology and Metabolism 2019
Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men
P Rorsman, FM Ashcroft
Physiological reviews 2018
The Vasculature in Prediabetes
DH Wasserman, TJ Wang, NJ Brown
Circulation research 2018
Glucose-Induced β-Cell Dysfunction In Vivo: Evidence for a Causal Role of C-jun N-terminal Kinase Pathway
C Tang, LS Yeung, K Koulajian, L Zhang, K Tai, A Volchuk, A Giacca
Endocrinology 2018
What Can Diabetes-Associated Genetic Variation in TCF7L2 Teach Us About the Pathogenesis of Type 2 Diabetes?
JD Adams, A Vella
Metabolic Syndrome and Related Disorders 2018
Increase in hepatic and decrease in peripheral insulin clearance characterize abnormal temporal patterns of serum insulin in diabetic subjects
K Ohashi, M Fujii, S Uda, H Kubota, H Komada, K Sakaguchi, W Ogawa, S Kuroda
npj Systems Biology and Applications 2018
The effects of kisspeptin on β-cell function, serum metabolites and appetite in humans
C Izzi-Engbeaya, AN Comninos, SA Clarke, A Jomard, L Yang, S Jones, A Abbara, S Narayanaswamy, PC Eng, D Papadopoulou, JK Prague, P Bech, IF Godsland, P Bassett, C Sands, S Camuzeaux, M Gomez-Romero, JT Pearce, MR Lewis, E Holmes, JK Nicholson, T Tan, R Ratnasabapathy, M Hu, G Carrat, L Piemonti, M Bugliani, P Marchetti, PR Johnson, SJ Hughes, AM Shapiro, GA Rutter, WS Dhillo
Diabetes, obesity & metabolism 2018
Glucose effectiveness is a critical pathogenic factor leading to glucose intolerance and type 2 diabetes: An ignored hypothesis
FP Alford, JE Henriksen, C Rantzau, H Beck-Nielsen
Diabetes/Metabolism Research and Reviews 2018
The Need to Calculate Target Glucose Levels When Measuring Changes in Insulin Sensitivity During Interventions for Individuals With Type 2 Diabetes
NA Othman, PD Docherty, JD Krebs, DA Bell, JG Chase
Journal of diabetes science and technology 2018
Overnight glucose control in people with type 1 diabetes
D Boiroux, AK Duun-Henriksen, S Schmidt, K Nørgaard, S Madsbad, NK Poulsen, H Madsen, JB Jørgensen
Biomedical Signal Processing and Control 2018
A Mouse Model of Beta-Cell Dysfunction as Seen in Human Type 2 Diabetes
JH Parilla, JR Willard, BM Barrow, S Zraika
Journal of Diabetes Research 2018
Asymptomatic Reactive Hypoglycemia and Inflammatory Reaction in Patients with Coronary Artery Disease
M Murata, H Adachi, S Oshima, M Kurabayashi
International Heart Journal 2018
Best Use of Models to Advance the Artificial Pancreas
GM Steil
Diabetes Technology & Therapeutics 2018
Interpretation of Retrospective BG Measurements
KW Stewart, CG Pretty, GM Shaw, JG Chase
Journal of diabetes science and technology 2018
Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables
JM Wentworth, NG Bediaga, LC Giles, M Ehlers, SE Gitelman, S Geyer, C Evans-Molina, LC Harrison
Diabetologia 2018
Quantitative approaches to energy and glucose homeostasis: machine learning and modelling for precision understanding and prediction
T McGrath, KG Murphy, NS Jones
Journal of The Royal Society Interface 2018
Unannounced Meals in the Artificial Pancreas: Detection Using Continuous Glucose Monitoring
C Ramkissoon, P Herrero, J Bondia, J Vehi
Sensors (Basel, Switzerland) 2018
Sensor-Augmented Pump-Based Customized Mathematical Model for Type 1 Diabetes
B Grosman, D Wu, D Miller, L Lintereur, A Roy, N Parikh, FR Kaufman
Diabetes Technology & Therapeutics 2018
Metabolic markers, regional adiposity, and adipose cell size: relationship to insulin resistance in African-American as compared with Caucasian women
C Allister-Price, CM Craig, D Spielman, SS Cushman, TL McLaughlin
International Journal of Obesity 2018
Immunohistochemical expression of insulin, glucagon, and somatostatin in pancreatic islets of horses with and without insulin resistance
KM Newkirk, G Ehrensing, A Odoi, RC Boston, N Frank
American Journal of Veterinary Research 2018
Personalizing physical exercise in a computational model of fuel homeostasis
MC Palumbo, M Morettini, P Tieri, F Diele, M Sacchetti, F Castiglione, NL Komarova
PLoS computational biology 2018
Validity of triglyceride–glucose index as an indicator for metabolic syndrome in children and adolescents: the CASPIAN-V study
P Angoorani, R Heshmat, HS Ejtahed, ME Motlagh, H Ziaodini, M Taheri, T Aminaee, A Goodarzi, M Qorbani, R Kelishadi
Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity 2018
Insulin Resistance, Hyperinsulinemia, and LH: Relative Roles in Peripubertal Obesity-Associated Hyperandrogenemia
CM Solorzano, KL Knudsen, AD Anderson, EG Hutchens, JS Collins, JT Patrie, JC Marshall, CR McCartney
The Journal of clinical endocrinology and metabolism 2018
Maternal obesity increases insulin resistance, low-grade inflammation and osteochondrosis lesions in foals and yearlings until 18 months of age
M Robles, E Nouveau, C Gautier, L Mendoza, C Dubois, M Dahirel, B Lagofun, MC Aubrière, JP Lejeune, I Caudron, I Guenon, C Viguié, L Wimel, H Bouraima-Lelong, D Serteyn, A Couturier-Tarrade, P Chavatte-Palmer, C Fürnsinn
PloS one 2018
Insulin sensitivity assessed using urine C peptide creatinine ratio (UCPCR) in pregnancy: cross-sectional analysis of an English multiethnic cohort
A Markoska, LC Mendoza, R Valaiyapathi, C Thorn, A Dornhorst
BMJ Open 2018
Identifiability Analysis of Three Control-Oriented Models for Use in Artificial Pancreas Systems
J Garcia-Tirado, C Zuluaga-Bedoya, MD Breton
Journal of diabetes science and technology 2018
Evolution of blood pressure control identification in lieu of post-surgery diabetic patients: a review
AA Basha, S Vivekanandan, P Parthasarathy
Health Information Science and Systems 2018
Diabetes. Epidemiology, Genetics, Pathogenesis, Diagnosis, Prevention, and Treatment
E Bonora, R DeFronzo
2018
Glucagon secretion determined by the RIA method is lower in patients with low left ventricular ejection fraction: The New Glass Study
M Murata, H Adachi, T Nakade, S Oshima
Diabetes Research and Clinical Practice 2018
Assessment of glucose effectiveness from short IVGTT in individuals with different degrees of glucose tolerance
M Morettini, FD Nardo, L Burattini, S Fioretti, C Göbl, A Kautzky-Willer, G Pacini, A Tura
Acta Diabetologica 2018
An extensible mathematical model of glucose metabolism. Part I: the basic glucose-insulin-glucagon model, basal conditions and basic dynamics
CL Adams, DG Lasseigne
2018
Blood glucose control using an ABC algorithm-based fuzzy-PID controller
S SOYLU, K DANIŞMAN
TURK J ELECTR ENG CO 2018
Adaptive model predictive control for a dual-hormone artificial pancreas
D Boiroux, V Bátora, M Hagdrup, SL Wendt, NK Poulsen, H Madsen, JB Jørgensen
Journal of Process Control 2018
Higher Order Sliding Mode Control for Blood Glucose Regulation of Type 1 Diabetic Patients:
M Djouima, AT Azar, S Drid, D Mehdi
International Journal of System Dynamics Applications 2018
Blood glucose regulation in type 1 diabetic patients: an adaptive parametric compensation control-based approach
A Nath, D Deb, R Dey, S Das
IET Systems Biology 2018
Parameter and State Estimation of a Mathematical Model of Carbohydrate Intake
A Olay-Blanco, A Rodriguez-Liñan, G Quiroz
IFAC-PapersOnLine 2018
Adaptive Fuzzy Integral Sliding Mode Control of Blood Glucose Level in Patients with Type 1 Diabetes: in silico Studies
S Asadi, V Nekoukar
Mathematical Biosciences 2018
Design of cybernetic model for glucose clamp techniques
M Rebro, M Tarnik, E Miklovicova, J Murgas
2018
Fuzzy type-2 fractional Backstepping blood glucose control based on sliding mode observer
H Heydarinejad, H Delavari, D Baleanu
2018
Quantitative path to deep phenotyping: Possible importance of reduced hepatic insulin degradation to type 2 diabetes mellitus pathogenesis: Quantitative path to deep phenotyping: Possible importance of reduced hepatic insulin degradation to type 2 diabetes mellitus pathogenesis
RN Bergman, F Piccinini, IA Bediako, M Kabir, C Kolka, D Polidori, M Ader
Journal of Diabetes 2018
Differential contribution of chronic binge alcohol and antiretroviral therapy to metabolic dysregulation in SIV-infected male macaques
SM Ford, LS Peter, P Berner, G Cook, CV Stouwe, J Dufour, G Bagby, S Nelson, PE Molina
American journal of physiology. Endocrinology and metabolism 2018
Maternal Western diet during gestation and lactation modifies adult offspring’s cognitive and hedonic brain processes, behavior, and metabolism in Yucatan minipigs
Y Gautier, I Luneau, N Coquery, P Meurice, CH Malbert, S Guerin, B Kemp, JE Bolhuis, C Clouard, IL Huërou-Luron, S Blat, D Val-Laillet
The FASEB Journal 2018
The Effects of Oral Magnesium Supplementation on Glycemic Response among Type 2 Diabetes Patients
W ELDerawi, I Naser, M Taleb, A Abutair
Nutrients 2018
Patient-Specific Controller for an Implantable Artificial Pancreas
Y Ho
2018
Innovations in Infrastructure: Proceedings of ICIIF 2018
D Deb, VE Balas, R Dey
2018
Diabetes Epidemiology, Genetics, Pathogenesis, Diagnosis, Prevention, and Treatment
E Bonora, RA DeFronzo
2018
Terminal Synergetic Control for Blood Glucose Regulation in Diabetes Patients
A Hachana, MN Harmas
Journal of Dynamic Systems Measurement and Control 2018
Is Absence of Carbohydrate Metabolism Disorders in Patients with Prolonged History of Obesity due to Low Insulin Resistance or Preserved Insulin Secretion?
EA Shestakova, IA Sklyanik, AS Panevina, MV Shestakova
2018
Artificial pancreas: glycemic control strategies for avoiding hypoglycemia
JE Sereno, MA Caicedo, PS Rivadeneira
2018
An Extensible Mathematical Model of Glucose Metabolism. Part I: The Basic Glucose-Insulin-Glucagon Model, Basal Conditions and Basic Dynamics
C Adams, D Lasseigneb
2018
Generalized extended state observer design for the estimation of the rate of glucose appearance in artificial pancreas
I Sala, JL Diez, J Bondia
2018
A T-S Fuzzy Model-Based Algorithm for Blood Glucose Control in Diabetic Patients
Z Kang, J Pan, W Zhang, X Zou
2018
Quantitative path to deep phenotyping: Possible importance of reduced hepatic insulin degradation to type 2 diabetes mellitus pathogenesis: 深度表型的定量途径:对于2型糖尿病发病机制来说减少肝脏胰岛素降解可能具有意义
RN Bergman, F Piccinini, IA Bediako, M Kabir, C Kolka, D Polidori, M Ader
Journal of Diabetes 2018
Blood glucose regulation in type 1 diabetic patients: an adaptive parametric compensation control-based approach.
Nath A, Deb D, Dey R, Das S
IET Systems Biology 2018
Considerations and guidelines for mouse metabolic phenotyping in diabetes research
T Alquier, V Poitout
Diabetologia 2017
Regulator of G protein signaling 2 is a key regulator of pancreatic β-cell mass and function
H Dong, Y Zhang, J Wang, DS Kim, H Wu, B Sjögren, W Gao, L Luttrell, H Wang
Cell Death and Disease 2017
How Should We Think About the Role of the Brain in Glucose Homeostasis and Diabetes?
JD Deem, K Muta, JM Scarlett, GJ Morton, MW Schwartz
Diabetes 2017
Evidence That the Sympathetic Nervous System Elicits Rapid, Coordinated, and Reciprocal Adjustments of Insulin Secretion and Insulin Sensitivity During Cold Exposure
GJ Morton, K Muta, KJ Kaiyala, JM Rojas, JM Scarlett, ME Matsen, JT Nelson, NK Acharya, F Piccinini, D Stefanovski, RN Bergman, GJ Taborsky, SE Kahn, MW Schwartz
Diabetes 2017
Lecture Notes in Electrical Engineering
H Heydarinejad, H Delavari
Lecture Notes in Electrical Engineering 2017
Relationship Between β-cell Response and Insulin Sensitivity in Horses based on the Oral Sugar Test and the Euglycemic Hyperinsulinemic Clamp
S Lindåse, K Nostell, J Söder, J Bröjer
Journal of Veterinary Internal Medicine 2017
Impact of glycated hemoglobin (HbA1c) on identifying insulin resistance among apparently healthy individuals
S Saha, PE Schwarz
Journal of Public Health 2017
Effect of adrenal medullectomy on metabolic responses to chronic intermittent hypoxia in the frequently sampled intravenous glucose tolerance test
MK Shin, W Han, H Joo, S Bevans-Fonti, M Shiota, D Stefanovski, VY Polotsky
Journal of applied physiology 2017
Optimal meal time after bolusing for Type 1 diabetes patients under meal uncertainties
S Nandi, T Singh, LD Mastrandrea, P Singla
2017 American Control Conference (ACC) 2017
Effects of maternal and fetal LEP common variants on maternal glycemic traits in pregnancy
R Lin, H Ju, Z Yuan, C Zhang, L Zeng, Y Sun, Z Su, L Jin
Scientific Reports 2017
PharmML in Action: an Interoperable Language for Modeling and Simulation: PharmML in Action
R Bizzotto, E Comets, G Smith, F Yvon, NR Kristensen, MJ Swat
CPT Pharmacometrics Syst. Pharmacol. 2017
Preventing diabetes in obese Latino youth with prediabetes: a study protocol for a randomized controlled trial
EG Soltero, YP Konopken, ML Olson, CS Keller, FG Castro, AN Williams, DL Patrick, S Ayers, HH Hu, M Sandoval, J Pimentel, WC Knowler, KD Frick, GQ Shaibi
BMC Public Health 2017
Early Pregnancy Biochemical Predictors of Gestational Diabetes Mellitus
CE Powe
Current Diabetes Reports 2017
Association of maternal and fetal LEPR common variants with maternal glycemic traits during pregnancy
R Lin, H Ju, Z Yuan, L Zeng, Y Sun, Z Su, Y Yang, Y Wang, L Jin
Scientific Reports 2017
High fat feeding unmasks variable insulin responses in male C57BL/6 mouse substrains
RL Hull, JR Willard, MD Struck, BM Barrow, GS Brar, S Andrikopoulos, S Zraika
Journal of Endocrinology 2017
Maternal Nutrition during Pregnancy Affects Testicular and Bone Development, Glucose Metabolism and Response to Overnutrition in Weaned Horses Up to Two Years
M Robles, C Gautier, L Mendoza, P Peugnet, C Dubois, M Dahirel, JP Lejeune, I Caudron, I Guenon, S Camous, A Tarrade, L Wimel, D Serteyn, H Bouraima-Lelong, P Chavatte-Palmer, C Fürnsinn
PloS one 2017
Cardiometabolic Risk in PCOS: More than a Reproductive Disorder
LC Torchen
Current Diabetes Reports 2017
Modelling Optimization and Control of Biomedical Systems
EN Pistikopoulos, I Naşcu, EG Velliou
2017
Glucose fluctuation and the resultant endothelial injury are correlated with pancreatic β cell dysfunction in patients with coronary artery disease
M Murata, H Adachi, S Oshima, M Kurabayashi
Diabetes Research and Clinical Practice 2017
Fractional adaptive control for a fractional - order insuline - glucose dynamic model
S Coman, C Boldisor, L Floroian
2017
Prevalence of polycystic ovary syndrome in Chinese obese women of reproductive age with or without metabolic syndrome
P Liang, L Xi, J Shi, W Li, S Zhao, Y Deng, R Wang, Y Sun, B Gu, L Yuan, Y Zhang, W Gu, W Wang, J Hong
Fertility and Sterility 2017
Human glycemic response curves after intake of carbohydrate foods are accurately predicted by combining in vitro gastrointestinal digestion with in silico kinetic modeling
S Bellmann, M Minekus, P Sanders, S Bosgra, R Havenaar
Clinical Nutrition Experimental 2017
Model for Simulating Fasting Glucose in Type 2 Diabetes and the Effect of Adherence to Treatment 1 1This project is funded by Innovation Fund Denmark through the Industrial PhD project 5189-00033B, and the Danish Diabetes Academy supported by the Novo Nordisk Foundation
TB Aradóttir, D Boiroux, H Bengtsson, J Kildegaard, BV Orden, JB Jørgensen
IFAC-PapersOnLine 2017
Study of Two Time Delays in IVGTT Glucose–Insulin Dynamical System
S Rathee, Nilam
2017
Prevention of type 2 diabetes mellitus in polycystic ovary syndrome: A review
S Anwar, N Shikalgar
Diabetes & Metabolic Syndrome: Clinical Research & Reviews 2017
Model Order Reduction of Glucose-Insulin Homeostasis Using Empirical Gramians and Balanced Truncation * *This work was supported by IAV Automotive Engineering GmbH, Berlin, Germany
C Tolks, C Ament
IFAC-PapersOnLine 2017
Asymptotic tracking and disturbance rejection of the blood glucose regulation system
B Ashley, W Liu
Mathematical Biosciences 2017
Meal detection based on non-individualized moving horizon estimation and classification
K Kolle, AL Fougner, O Stavdahl
2017
Improvement of glycemic control in critically ill patients using online identification of insulin sensitivity
S Wu, E Furutani
2017
Strategic Trust in Cloud-Enabled Cyber-Physical Systems With an Application to Glucose Control
J Pawlick, Q Zhu
IEEE T INF FOREN SEC 2017
Genetic algorithm-based interval type-2 fuzzy model identification for people with type-1 diabetes
TC Lin, YJ Huang, JI Lin, VE Balas, S Srinivasan
2017
Positive sliding mode control for blood glucose regulation
K Menani, T Mohammadridha, N Magdelaine, M Abdelaziz, CH Moog
International Journal of Systems Science 2017
Identification of parameters of the glucose-insulin homeostasis under everyday live conditions
C Tolks, C Ament
2017
Multivariate Statistical Monitoring of Sensor Faults of A Multivariable Artificial Pancreas
K Turksoy, I Hajizadeh, E Littlejohn, A Cinar
IFAC-PapersOnLine 2017
Linear parameter varying (LPV) based robust control of type-I diabetes driven for real patient data
L Kovács
Knowledge-Based Systems 2017
Soft Computing Applications
VE Balas, LC Jain, MM Balas
2017
The Effect of Improved Serum 25-Hydroxyvitamin D Status on Glycemic Control in Diabetic Patients: A Meta-Analysis
N Mirhosseini, H Vatanparast, M Mazidi, SM Kimball
The Journal of clinical endocrinology and metabolism 2017
Effects of dietary energy allowance and decline in dry matter intake during the dry period on responses to glucose and insulin in transition dairy cows
S Salin, A Vanhatalo, K Elo, J Taponen, RC Boston, T Kokkonen
Journal of Dairy Science 2017
Meal Detection in the Artificial Pancreas: Implications During Exercise * *This work was funded by the Spanish Government through grants DPI2013-46982-C2-1-R and DPI2013-46982-C2-2-R, the University of Girona through grant BR2014/51, and the European Union through FEDER Funds
CM Ramkissoon, P Herrero, J Bondia, J Vehi
IFAC-PapersOnLine 2017
Adaptive Control with Heuristic Disturbance Rejection in T1DM: A Performance Assessment 1 1This work has been supported by Slovak scientific grant agency through grant VEGA 1/0475/16
M Rebro, M Tárník, J Murgaš
IFAC-PapersOnLine 2017
Insulin injections and exercise scheduling for individuals with diabetes: An optimal control model: Optimal control of diabetes
ZA Helal, V Rehbock, R Loxton
Optimal Control Applications and Methods 2017
How should we interpret retrospective blood glucose measurements? Sampling and Interpolation
KW Stewart, F Thomas, C Pretty, JG Chase, GM Shaw
IFAC-PapersOnLine 2017
VII Latin American Congress on Biomedical Engineering CLAIB 2016, Bucaramanga, Santander, Colombia, October 26th -28th, 2016
I Torres, J Bustamante, DA Sierra
2017
Non-iterative SOS-based approach for guaranteed cost control design of polynomial systems with input saturation
N Vafamand, MM Mardani, A Khayatian, M Shasadeghi
IET CONTROL THEORY A 2017
Impulsive Zone MPC for Type I Diabetic Patients based on a long-term model
AH González, PS Rivadeneira, A Ferramosca, N Magdelaine, CH Moog
IFAC-PapersOnLine 2017
Review of methods for measuring β-cell function: Design considerations from the Restoring Insulin Secretion (RISE) Consortium: HANNON et al
TS Hannon, SE Kahn, KM Utzschneider, TA Buchanan, KJ Nadeau, PS Zeitler, DA Ehrmann, SA Arslanian, S Caprio, SL Edelstein, PJ Savage, KJ Mather
Diabetes, obesity & metabolism 2017
Triglyceride and Glucose (TyG) Index is a Clinical Surrogate Marker for the Diagnosis of Metabolic Syndrome
KA Shin
Biomedical Science Letters 2017
A performance comparison between standard and impulsive ZMPC on type 1 diabetic patients
JE Sereno, AH Gonzalez, PS Rivadeneira
2017
Robust blood glucose regulation for Type II Diabetes Mellitus patients
KG Herrera, E Ruiz-Velazquez, J Garcia-Rodriguez
2017
Model Guided Deep Learning Approach Towards Prediction of Physical System Behavior
S Das, A Agrawal, A Banerjee, SK Gupta
2017
Control of MIMO nonlinear systems via approximate model inversion
GC Calafiore, C Novara
2017
Trends in Advanced Intelligent Control, Optimization and Automation: Proceedings of KKA 2017—The 19th Polish Control Conference, Kraków, Poland, June 18–21, 2017
W Mitkowski, J Kacprzyk, K Oprzędkiewicz, P Skruch
2017
Changes in beta cell function occur in prediabetes and early disease in the Lepr db mouse model of diabetes
OH Do, JE Gunton, HY Gaisano, P Thorn
Diabetologia 2016
Bariatric surgery and type 2 diabetes: are there weight loss-independent therapeutic effects of upper gastrointestinal bypass?
M Chondronikola, LL Harris, S Klein
Journal of Internal Medicine 2016
Handbook of Research on Trends in the Diagnosis and Treatment of Chronic Conditions:
K Zarkogianni, K Nikita
Handbook of Research on Trends in the Diagnosis and Treatment of Chronic Conditions: 2016
Mycoprotein reduces energy intake and postprandial insulin release without altering glucagon-like peptide-1 and peptide tyrosine-tyrosine concentrations in healthy overweight and obese adults: a randomised-controlled trial
JH Bottin, JR Swann, E Cropp, ES Chambers, HE Ford, MA Ghatei, GS Frost
British Journal of Nutrition 2016
Meal Detection in Patients With Type 1 Diabetes: A New Module for the Multivariable Adaptive Artificial Pancreas Control System
K Turksoy, S Samadi, J Feng, E Littlejohn, L Quinn, A Cinar
IEEE J BIOMED HEALTH 2016
Relationship between insulin sensitivity and insulin secretion rate: not necessarily hyperbolic
SH Kim, A Silvers, J Viren, GM Reaven
Diabetic Medicine 2016
Predicting Glucose Effectiveness in Chinese Participants Using Routine Measurements
YL Chen, SF Lee, C Pei, D Pei, CH Lee, CT He, YJ Liang, JD Lin
Metabolic Syndrome and Related Disorders 2016
Model-Based Quantification of Glucagon-Like Peptide-1–Induced Potentiation of Insulin Secretion in Response to a Mixed Meal Challenge
CD Man, F Micheletto, M Sathananthan, A Vella, C Cobelli
Diabetes Technology & Therapeutics 2016
Heterogeneous Contribution of Insulin Sensitivity and Secretion Defects to Gestational Diabetes Mellitus: Table 1
CE Powe, C Allard, MC Battista, M Doyon, L Bouchard, JL Ecker, P Perron, JC Florez, R Thadhani, MF Hivert
Diabetes care 2016
Baseline insulin sensitivity affects response to high-amylose maize resistant starch in women: a randomized, controlled trial
BA Gower, R Bergman, D Stefanovski, B Darnell, F Ovalle, G Fisher, SK Sweatt, HS Resuehr, C Pelkman
Nutrition & Metabolism 2016
Standardized Mixed-Meal Tolerance and Arginine Stimulation Tests Provide Reproducible and Complementary Measures of β-Cell Function: Results From the Foundation for the National Institutes of Health Biomarkers Consortium Investigative Series
SS Shankar, A Vella, RH Raymond, MA Staten, RA Calle, RN Bergman, C Cao, D Chen, C Cobelli, CD Man, M Deeg, JQ Dong, DS Lee, D Polidori, RP Robertson, H Ruetten, D Stefanovski, MT Vassileva, GC Weir, DA Fryburg
Diabetes care 2016
Bmal1 is required for beta cell compensatory expansion, survival and metabolic adaptation to diet-induced obesity in mice
K Rakshit, TW Hsu, AV Matveyenko
Diabetologia 2016
Exenatide Treatment Alone Improves β-Cell Function in a Canine Model of Pre-Diabetes
V Ionut, OO Woolcott, HJ Mkrtchyan, D Stefanovski, M Kabir, MS Iyer, H Liu, AV Castro, Q Wu, JL Broussard, CM Kolka, I Asare-Bediako, RN Bergman, ML Hribal
PloS one 2016
Establishment of a Refined Oral Glucose Tolerance Test in Pigs, and Assessment of Insulin, Glucagon and Glucagon-Like Peptide-1 Responses
E Manell, P Hedenqvist, A Svensson, M Jensen-Waern, E Xu
PloS one 2016
ODE models for the management of diabetes: A review
S Rathee, Nilam
International Journal of Diabetes in Developing Countries 2016
Development of a computational model of glucose toxicity in the progression of diabetes mellitus
M Cruz-Aponte, AE Torres-Colón, VL Torres-Torres, DT Pérez-Rivera
Mathematical Biosciences and Engineering 2016
Principles of Diabetes Mellitus
A Ohri, S Vergano, R Bhambri, SH Schneider
Principles of Diabetes Mellitus 2016
Blood Glucose Control of Critically Ill Patients with Time-varying Insulin Sensitivity Using Nonlinear Model Predictive Control
S Wu, E Furutani
Transactions of the Institute of Systems, Control and Information Engineers 2016
Fuzzy Control System for Regulating the Blood Glucose Level of Diabetes Patients Implemented on FPGA
SM Gharghory, DA El-Dib
Journal of Circuits Systems and Computers 2016
Model Identification using Continuous Glucose Monitoring Data for Type 1 Diabetes**This work has been funded by the Danish Diabetes Academy supported by the Novo Nordisk Foundation
D Boiroux, M Hagdrup, Z Mahmoudi, NK Poulsen, H Madsen, JB Jørgensen
IFAC-PapersOnLine 2016
Blood glucose regulation in diabetics. A flatness based nonlinear control simulation study
G Cocha, M Podestá, A Mazzadi, C Amorena, C DAtellis
Journal of physics. Conference series 2016
Estimation of insulin sensitivity in diabetic Göttingen Minipigs
BJ Misgeld, PG Tenbrock, K Lunze, JW Dietrich, S Leonhardt
Control Engineering Practice 2016
Adaptive control in an artificial pancreas for people with type 1 diabetes
D Boiroux, AK Duun-Henriksen, S Schmidt, K Nørgaard, NK Poulsen, H Madsen, JB Jørgensen
Control Engineering Practice 2016
Real-time insulin bolusing for unannounced meals with artificial pancreas
K Turksoy, I Hajizadeh, S Samadi, J Feng, M Sevil, M Park, L Quinn, E Littlejohn, A Cinar
Control Engineering Practice 2016
Medizintechnische Systeme
K Lunze, M Brendel
Medizintechnische Systeme 2016
Increased Metabolic Disorders and Impaired Insulin Secretory Function in the First-Degree Relatives of Type 2 Diabetic Patients with Normal Glucose Tolerance
L Deng, S Liu, Y Gong, H Tian, Y Liu, J Song, X Ran, H Yu, X Zhang, Y Long, Y Ren
Metabolic Syndrome and Related Disorders 2016
Nadolol reduces insulin sensitivity in liver cirrhosis: a randomized double-blind crossover trial: Nadolol and insulin sensitivity
WG Lee, R Murphy, JL McCall, EJ Gane, M Soop, A Tura, LD Plank
Diabetes/Metabolism Research and Reviews 2016
A Novel Insulin/Glucose Model after a Mixed-Meal Test in Patients with Type 1 Diabetes on Insulin Pump Therapy
L Marchetti, F Reali, M Dauriz, C Brangani, L Boselli, G Ceradini, E Bonora, RC Bonadonna, C Priami
Scientific Reports 2016
Mechanistic modeling of hemoglobin glycation and red blood cell kinetics enables personalized diabetes monitoring
R Malka, DM Nathan, JM Higgins
Science Translational Medicine 2016
The cutoff values of indirect indices for measuring insulin resistance for metabolic syndrome in Korean children and adolescents
JW Kim, SH Park, Y Kim, M Im, HS Han
Annals of Pediatric Endocrinology & Metabolism 2016
Performance Analysis of Fuzzy-PID Controller for Blood Glucose Regulation in Type-1 Diabetic Patients
J Yadav, A Rani, V Singh
Journal of Medical Systems 2016
Control Difuso con Estimador de Estados para Sistemas de Páncreas Artificial
R González, A Cipriano
Revista Iberoamericana de Automática e Informática Industrial RIAI 2016
Systems Pharmacology and Pharmacodynamics
DE Mager, HH Kimko
Systems Pharmacology and Pharmacodynamics 2016
An Adaptive Nonlinear Basal-Bolus Calculator for Patients With Type 1 Diabetes
D Boiroux, TB Aradóttir, K Nørgaard, NK Poulsen, H Madsen, JB Jørgensen
Journal of diabetes science and technology 2016
Exocrine and Endocrine Interactions in Cystic Fibrosis: A Potential Key to Understanding Insulin Secretion in Health and Disease?
C Cobelli, A Vella
Diabetes 2016
Dynamical compensation in physiological circuits
O Karin, A Swisa, B Glaser, Y Dor, U Alon
Molecular Systems Biology 2016
An ensemble nonlinear model predictive control algorithm in an artificial pancreas for people with type 1 diabetes
D Boiroux, M Hagdrup, Z Mahmoudi, NK Poulsen, H Madsen, JB Jorgensen
2016
States and unknown input estimation via non-linear sliding mode high-gain observers for a glucose-insulin system
AA Gonzalez, H Voos, M Darouach
2016
Linearity of β-cell response across the metabolic spectrum and to pharmacology: insights from a graded glucose infusion-based investigation series
SS Shankar, RR Shankar, LA Mixson, DL Miller, C Chung, C Cilissen, CR Beals, SA Stoch, HO Steinberg, DE Kelley
American journal of physiology. Endocrinology and metabolism 2016
Perturbation-Iteration Method for Solving Mathematical Model of Glucose and Insulin in Diabetic Human during Physical Activity
M Gahamanyi, JM Ntaganda, MS Haggar
Open Journal of Applied Sciences 2016
Enhanced insulin sensitivity mediated by adipose tissue browning perturbs islet morphology and hormone secretion in response to autonomic nervous activation in female mice
BA Omar, M Kvist-Reimer, S Enerbäck, B Ahrén
American journal of physiology. Endocrinology and metabolism 2016
Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test
M Staup, G Aoyagi, TQ Bayless, Y Wang, K Chng
Journal of visualized experiments : JoVE 2016
The Genetics of Type 2 Diabetes and Related Traits
JC Florez
2016
Dynamical compensation in physiological circuits.
Karin O, Swisa A, Glaser B, Dor Y, Alon U
Molecular Systems Biology 2016
Glucose Homeostatic Law: Insulin Clearance Predicts the Progression of Glucose Intolerance in Humans
K Ohashi, H Komada, S Uda, H Kubota, T Iwaki, H Fukuzawa, Y Komori, M Fujii, Y Toyoshima, K Sakaguchi, W Ogawa, S Kuroda, MO Hatakeyama
PloS one 2015
Temporal relationships between adipocytokines and diabetes risk in Hispanic adolescents with obesity: Cytokines and Diabetes Risk During Adolescence
BD Kayser, CM Toledo-Corral, TL Alderete, MJ Weigensberg, MI Goran
Obesity 2015
β-cell dysfunction: Its critical role in prevention and management of type 2 diabetes
Y Saisho
World journal of diabetes 2015
A therapy parameter-based model for predicting blood glucose concentrations in patients with type 1 diabetes
A Bock, G François, D Gillet
Computer Methods and Programs in Biomedicine 2015
Visceral adiposity index and insulin secretion and action in first-degree relatives of subjects with type 2 diabetes: Visceral Adiposity in Type 2 Diabetes
Y Yang, Y Feng, X Ma, K Chen, N Wu, D Wang, P Li, M Wang, Q Li, J Zhang
Diabetes/Metabolism Research and Reviews 2015
A fractional-order model for MINMOD Millennium
Y Cho, I Kim, D Sheen
Mathematical Biosciences 2015
The oral disposition index is a strong predictor of incident diabetes in Asian Indian prediabetic men
J Ram, C Snehalatha, S Selvam, A Nanditha, AS Shetty, IF Godsland, DG Johnston, A Ramachandran
Acta Diabetologica 2015
The necessity of identifying the basal glucose set-point in the IVGTT for patients with Type 2 Diabetes
NA Othman, PD Docherty, JD Krebs, DA Bell, JG Chase
BioMedical Engineering OnLine 2015
Impact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes
TH Hansen, H Vestergaard, T Jørgensen, ME Jørgensen, T Lauritzen, I Brandslund, C Christensen, O Pedersen, T Hansen, AP Gjesing
BMC Medical Genetics 2015
Imeglimin increases glucose-dependent insulin secretion and improves β-cell function in patients with type 2 diabetes
G Pacini, A Mari, P Fouqueray, S Bolze, M Roden
Diabetes Obesity and Metabolism 2015
High-Fat Diet-Induced Insulin Resistance Does Not Increase Plasma Anandamide Levels or Potentiate Anandamide Insulinotropic Effect in Isolated Canine Islets
OO Woolcott, JM Richey, M Kabir, RH Chow, MS Iyer, EL Kirkman, D Stefanovski, M Lottati, SP Kim, LN Harrison, V Ionut, D Zheng, IR Hsu, KJ Catalano, JD Chiu, H Bradshaw, Q Wu, RN Bergman, T Alquier
PloS one 2015
A Novel Insulin Resistance Index to Monitor Changes in Insulin Sensitivity and Glucose Tolerance: the ACT NOW Study
D Tripathy, JE Cobb, W Gall, KP Adam, T George, DC Schwenke, MA Banerji, GA Bray, TA Buchanan, SC Clement, RR Henry, AE Kitabchi, S Mudaliar, RE Ratner, FB Stentz, PD Reaven, N Musi, E Ferrannini, RA DeFronzo
The Journal of clinical endocrinology and metabolism 2015
Diabetes Remission after Nonsurgical Intensive Lifestyle Intervention in Obese Patients with Type 2 Diabetes
A Mottalib, M Sakr, M Shehabeldin, O Hamdy
Journal of Diabetes Research 2015
Association between systemic oxidative stress and insulin resistance/sensitivity indices - the PREDIAS study
S Kopprasch, D Srirangan, S Bergmann, J Graessler, PE Schwarz, SR Bornstein
Clinical Endocrinology 2015
Effects of Vitamin D Supplementation on C-peptide and 25-hydroxyvitamin D Concentrations at 3 and 6 Months
PD Chandler, EL Giovannucci, JB Scott, GG Bennett, K Ng, AT Chan, BW Hollis, N Rifai, KM Emmons, CS Fuchs, BF Drake
Scientific Reports 2015
Is the β-cell the key for remission of diabetes after bariatric surgery?: Perspectives
F Magkos, S Klein
The Journal of Physiology 2015
Inorganic nitrite improves components of the metabolic syndrome independent of weight change in a murine model of obesity and insulin resistance: Nitrite improves metabolic syndrome in obesity
S Singamsetty, Y Watanabe, L Guo, C Corey, Y Wang, J Tejero, BJ McVerry, MT Gladwin, S Shiva, CP O'Donnell
The Journal of Physiology 2015
Hyperinsulinism and polycystic ovary syndrome (PCOS): role of insulin clearance
MC Amato, R Vesco, E Vigneri, A Ciresi, C Giordano
Journal of Endocrinological Investigation 2015
Early Clinical Detection of Pharmacologic Response in Insulin Action in a Non-diabetic Insulin Resistant Population
SS Shankar, RR Shankar, RA Railkar, CR Beals, HO Steinberg, DE Kelley
Current Therapeutic Research 2015
Efficacy of nutrition therapy for glucose intolerance in Japanese women diagnosed with gestational diabetes based on IADPSG criteria during early gestation
I Horie, E Kawasaki, A Sakanaka, M Takashima, M Maeyama, T Ando, H Hanada, A Kawakami
Diabetes Research and Clinical Practice 2015
On-line policy learning and adaptation for real-time personalization of an artificial pancreas
MD Paula, GG Acosta, EC Martínez
Expert Systems with Applications 2015
International Textbook of Diabetes Mellitus: DeFronzo/International Textbook of Diabetes Mellitus, Fourth Edition
RN Bergman, M Ader
International Textbook of Diabetes Mellitus: DeFronzo/International Textbook of Diabetes Mellitus, Fourth Edition 2015
Observability criteria for impulsive control systems with applications to biomedical engineering processes
PS Rivadeneira, CH Moog
Automatica 2015
Decreased Insulin Secretion in Women with Previous Gestational Diabetes Mellitus
YP Lee, SK Lim, J Chang, E Jung, Y Choi, JY Oh, Y Hong, YA Sung, H Lee
The Ewha Medical Journal 2015
An Improved PID Algorithm Based on Insulin-on-Board Estimate for Blood Glucose Control with Type 1 Diabetes
R Hu, C Li
Computational and mathematical methods in medicine 2015
A New Insulin-Glucose Metabolic Model of Type 1 Diabetes Mellitus: An In Silico Study
Q Fang, L Yu, P Li
Computer Methods and Programs in Biomedicine 2015
A comprehensive compartmental model of blood glucose regulation for healthy and type 2 diabetic subjects
O Vahidi, KE Kwok, RB Gopaluni, FK Knop
Medical & Biological Engineering & Computing 2015
Morning Circadian Misalignment during Short Sleep Duration Impacts Insulin Sensitivity
RH Eckel, CM Depner, L Perreault, RR Markwald, MR Smith, AW McHill, J Higgins, EL Melanson, KP Wright
Current Biology 2015
Circadian Medicine: Colwell/Circadian Medicine
AV Matveyenko
Circadian Medicine: Colwell/Circadian Medicine 2015
Controlling blood glucose variability under uncertainty using reinforcement learning and Gaussian processes
MD Paula, LO Ávila, EC Martínez
Applied Soft Computing 2015
An active inference approach to on-line agent monitoring in safety–critical systems
L Avila, E Martínez
Advanced Engineering Informatics 2015
Mathematical analysis of a model for glucose regulation
K Fessel, JB Gaither, JK Bower, T Gaillard, K Osei, GA Rempala
Mathematical Biosciences and Engineering 2015
A Bolus Calculator Based on Continuous-Discrete Unscented Kalman Filtering for Type 1 Diabetics∗∗Funded by the Danish Diabetes Academy supported by the Novo Nordisk Foundation. Contact information: John Bagterp Jørgensen (jbjo@dtu.dk)
D Boiroux, TB Aradóttir, M Hagdrup, NK Poulsen, H Madsen, JB Jørgensen
IFAC-PapersOnLine 2015
Real-Time Insulin Bolusing for Unannounced Meals Using CGM Measurements
K Turksoy, A Cinar
IFAC-PapersOnLine 2015
Comparison of Prediction Models for a Dual-Hormone Artificial Pancreas∗∗Funded by the Danish Diabetes Academy supported by the Novo Nordisk Foundation. Contact information: John Bagterp J_rgensen(jbjo@dtu.dk)
D Boiroux, V Bátora, M Hagdrup, M Tárnik, J Murgaš, S Schmidt, K Nørgaard, NK Poulsen, H Madsen, JB Jørgensen
IFAC-PapersOnLine 2015
Circadian Disruption and Diet-Induced Obesity Synergize to Promote Development of β-Cell Failure and Diabetes in Male Rats
J Qian, B Yeh, K Rakshit, CS Colwell, AV Matveyenko
Endocrinology 2015
Development and assessment of the disposition index based on the oral glucose tolerance test in subjects with different glycaemic status
JL Santos, I Yévenes, LR Cataldo, M Morales, J Galgani, C Arancibia, J Vega, P Olmos, M Flores, JP Valderas, F Pollak
Journal of Physiology and Biochemistry 2015
A simplification of Cobelli’s glucose–insulin model for type 1 diabetes mellitus and its FPGA implementation
P Li, L Yu, Q Fang, SY Lee
Medical & Biological Engineering & Computing 2015
A Model-Based Approach to Support Validation of Medical Cyber-Physical Systems
L Silva, H Almeida, A Perkusich, M Perkusich
Sensors (Basel, Switzerland) 2015
A grid-based tool for optimal performance monitoring of a glycemic regulator: A grid-based tool for optimal performance monitoring
L Ávila, E Martínez
Optimal Control Applications and Methods 2015
Effects of Exercise on Hypertension
LS Pescatello
2015
Approach to assessing determinants of glucose homeostasis in the conscious mouse
CC Hughey, DH Wasserman, RS Lee-Young, L Lantier
Mammalian Genome 2014
Effects of aldosterone on insulin sensitivity and secretion
JM Luther
Steroids 2014
Prediction of future risk of insulin resistance and metabolic syndrome based on Korean boy's metabolite profiling
AJ Lee, HB Jang, M Ra, Y Choi, HJ Lee, JY Park, JH Kang, KH Park, SI Park, J Song
Obesity Research & Clinical Practice 2014
Estimation of insulin sensitivity in children: methods, measures and controversies: Insulin sensitivity in children
RJ Brown, JA Yanovski
Pediatric Diabetes 2014
Assessment of pancreatic β-cell function: review of methods and clinical applications
E Cersosimo, C Solis-Herrera, ME Trautmann, J Malloy, CL Triplitt
Current diabetes reviews 2014
Novel individual metabolic profile characterizes the protein kinase B-alpha ( pkb α − / − ) in vivo model
C Eberle, M Niessen, BA Hemmings, O Tschopp, C Ament
Archives Of Physiology And Biochemistry 2014
Changes in Insulin Sensitivity and Insulin Secretion with the Sodium Glucose Cotransporter 2 Inhibitor Dapagliflozin
S Mudaliar, RR Henry, G Boden, S Smith, AG Chalamandaris, D Duchesne, N Iqbal, J List
Diabetes Technology & Therapeutics 2014
Methods for the Assessment of Insulin Resistance
H Lee
Journal of Korean Diabetes 2014
Nonlinear glucose–insulin control considering delays—Part II: Control algorithm
K Mythreyi, SC Subramanian, RK Kumar
Control Engineering Practice 2014
Intensive insulin therapy for critically ill subjects based on direct data-driven model predictive control
Y Wang, M Fang, X Jiang, BW Bequette, H Xie
Journal of Process Control 2014
Identification of individualised empirical models of carbohydrate and insulin effects on T1DM blood glucose dynamics
M Cescon, R Johansson, E Renard, A Maran
International Journal of Control 2014
Post-meal β-cell function predicts the efficacy of glycemic control in patients with type 2 diabetes inadequately controlled by metformin monotherapy after addition of glibenclamide or acarbose
PH Chen, YT Tsai, JS Wang, SD Lin, WJ Lee, SL Su, IT Lee, ST Tu, YH Tseng, WH Sheu, SY Lin
Diabetology & metabolic syndrome 2014
Systems analysis and the prediction and prevention of Type 2 diabetes mellitus
RN Bergman, D Stefanovski, SP Kim
Current Opinion in Biotechnology 2014
Metabolic response to 36 hours of fasting in young men born small vs appropriate for gestational age
SW Jørgensen, C Brøns, L Bluck, L Hjort, K Færch, A Thankamony, L Gillberg, M Friedrichsen, DB Dunger, AA Vaag
Diabetologia 2014
Assessment of type II diabetes mellitus using irregularly sampled measurements with missing data
M Barazandegan, F Ekram, E Kwok, B Gopaluni, A Tulsyan
Bioprocess and Biosystems Engineering 2014
The Oral Minimal Model Method
C Cobelli, CD Man, G Toffolo, R Basu, A Vella, R Rizza
Diabetes 2014
Circadian Misalignment Augments Markers of Insulin Resistance and Inflammation, Independently of Sleep Loss
R Leproult, U Holmback, EV Cauter
Diabetes 2014
Adjusting Glucose-Stimulated Insulin Secretion for Adipose Insulin Resistance: An Index of  -Cell Function in Obese Adults
SK Malin, SR Kashyap, J Hammel, Y Miyazaki, RA DeFronzo, JP Kirwan
Diabetes care 2014
ß-cell function in type 2 diabetes
E Ferrannini, A Mari
Metabolism 2014
Process Systems Engineering: PISTIKOPOULOS:PSE O-BK
F Galvanin, M Barolo, S Macchietto, F Bezzo
Process Systems Engineering: PISTIKOPOULOS:PSE O-BK 2014
Hypoglycemic effects and mechanisms of electroacupuncture on insulin resistance
J Yin, J Kuang, M Chandalia, D Tuvdendorj, B Tumurbaatar, N Abate, JD Chen
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2014
Uncoupling of Ca v 1.2 From Ca 2+ -Induced Ca 2+ Release and SK Channel Regulation in Pancreatic β-Cells
Y Wang, RE Jarrard, EP Pratt, ML Guerra, AE Salyer, AM Lange, IM Soderling, GH Hockerman
Molecular Endocrinology 2014
A Review of Mathematical Model Describing Insulin Delivery System for Type 1 Diabetes
NF Yusof, AM Som, AS Ibrehem, SA Ali
Journal of Applied Sciences 2014
Disposition index identifies defective beta-cell function in cystic fibrosis subjects with normal glucose tolerance
L Merjaneh, Q He, Q Long, LS Phillips, AA Stecenko
Journal of Cystic Fibrosis 2014
Efficacy of metformin-based oral antidiabetic drugs is not inferior to insulin glargine in newly diagnosed type 2 diabetic patients with severe hyperglycemia after short-term intensive insulin therapy: Metformin and glargine in T2DM after IIT
Q Cheng, S Yang, C Zhao, Z Wang, Z Feng, R Li, P Ye, S Zhang, H Deng, B Zhou, J Long, L Gong, H Qing, C Luo, Q Li
Journal of Diabetes 2014
Prevalence of Diabetes, Prediabetes and Stress Hyperglycemia, Insulin Therapy and Metabolic Control in Patients on Total Parenteral Nutrition (Prospective Multicenter Study)
G Olveira, MJ Tapia, J Ocón, C Cabrejas-Gómez, MD Ballesteros-Pomar, A Vidal-Casariego, C Arraiza-Irigoyen, J Olivares, MC Conde-García, Á García-Manzanares, F Botella-Romero, RP Quílez-Toboso, L Cabrerizo, P Matía, L Chicharro, R Burgos, P Pujante, M Ferrer, A Zugasti, E Petrina, L Manjón, M Diéguez, MJ Carrera, A Vila-Bundo, JR Urgelés, C Aragón-Valera, O Sánchez-Vilar, I Bretón, P García-Peris, A Muñoz-Garach, E Márquez, D Olmo, JL Pereira, MC Tous
Endocrine Practice 2014
Predicting Plasma Glucose From Interstitial Glucose Observations Using Bayesian Methods
AH Hansen, AK Duun-Henriksen, R Juhl, S Schmidt, K Norgaard, JB Jorgensen, H Madsen
Journal of diabetes science and technology 2014
Modeling Impulsive Insulin Delivery in Insulin Pump with Time Delays
X Song, M Huang, J Li
SIAM Journal on Applied Mathematics 2014
Pituitary Lesions, Obesity, and Mesenteric Lipomas in Insulin-Resistant Horses
KM Newkirk, KA Chameroy, EM Tadros, BW Rohrbach, N Frank
Open Journal of Veterinary Medicine 2014
Hopf Bifurcation of a Two Delay Mathematical Model of Glucose and Insulin during Physical Activity
JM Ntaganda
Open Journal of Applied Sciences 2014
Determining the relative efficacy of a number of PID and PD models that relate insulin secretion to bolus induced glucose excursions
NA Othman, PD Docherty, JG Chase
IFAC Proceedings Volumes 2014
Assessment of Model Predictive and Adaptive Glucose Control Strategies for People with Type 1 Diabetes
D Boiroux, AK Duun-Henriksen, S Schmidt, K Nørgaard, NK Poulsen, H Madsen, JB Jørgensen
IFAC Proceedings Volumes 2014
A nonlinear blind identification approach to modeling of diabetic patients
C Novara, NM Pour, T Vincent, G Grassi
IFAC Proceedings Volumes 2014
Artificial Blood Glucose Control using a DDE Modelling Approach
M Penet, H Gueguen, A Belmiloudi
IFAC Proceedings Volumes 2014
The regulation of glucose metabolism: implications and considerations for the assessment of glucose homeostasis in rodents
GM Kowalski, CR Bruce
American journal of physiology. Endocrinology and metabolism 2014
A Bayesian network for modelling blood glucose concentration and exercise in type 1 diabetes
SM Ewings, SK Sahu, JJ Valletta, CD Byrne, AJ Chipperfield
Statistical Methods in Medical Research 2014
Impact of glucose dosing regimens on modeling of glucose tolerance and β -cell function by intravenous glucose tolerance test in diet-induced obese mice
BA Omar, G Pacini, B Ahrén
Physiological Reports 2014
Data-driven Modeling for Diabetes: Diagnosis and Treatment
V Marmarelis, G Mitsis
2014
Exogenous glucose administration impairs glucose tolerance and pancreatic insulin secretion during acute sepsis in non-diabetic mice
Y Watanabe, S Singamsetty, B Zou, L Guo, D Stefanovski, LC Alonso, A Garcia-Ocana, CP O'Donnell, BJ McVerry
PloS one 2013
Human systems immunology: Hypothesis-based modeling and unbiased data-driven approaches
A Arazi, WF Pendergraft, RM Ribeiro, AS Perelson, N Hacohen
Seminars in Immunology 2013
A Novel Mathematical Model Detecting Early Individual Changes of Insulin Resistance
C Eberle, W Palinski, C Ament
Diabetes Technology & Therapeutics 2013
Pioglitazone Slows Progression of Atherosclerosis in Prediabetes Independent of Changes in Cardiovascular Risk Factors
A Saremi, DC Schwenke, TA Buchanan, HN Hodis, WJ Mack, MA Banerji, GA Bray, SC Clement, RR Henry, AE Kitabchi, S Mudaliar, RE Ratner, FB Stentz, N Musi, D Tripathy, RA DeFronzo, PD Reaven
Arteriosclerosis, thrombosis, and vascular biology 2013
Calcineurin Inhibition and New-Onset Diabetes Mellitus After Transplantation:
HA Chakkera, LJ Mandarino
Transplantation 2013
Insulin sensitivity and brain reward activation in overweight Hispanic girls: a pilot study: Insulin sensitivity and brain reward
TC Adam, S Tsao, KA Page, H Hu, RE Hasson, MI Goran
Pediatric Obesity 2013
Interventions to Preserve Beta-Cell Function in the Management and Prevention of Type 2 Diabetes
KA Page, T Reisman
Current Diabetes Reports 2013
Shape information from glucose curves: Functional data analysis compared with traditional summary measures
KF Frøslie, J Røislien, E Qvigstad, K Godang, J Bollerslev, N Voldner, T Henriksen, MB Veierød
BMC medical research methodology 2013
Estrogen-related receptor β deletion modulates whole-body energy balance via estrogen-related receptor γ and attenuates neuropeptide Y gene expression
MS Byerly, MA Salayta, RD Swanson, K Kwon, JM Peterson, Z Wei, S Aja, TH Moran, S Blackshaw, GW Wong
European Journal of Neuroscience 2013
New evidence for an association between liver enzymes and pancreatic islet β-cell dysfunction in young obese patients
L Wang, J Zhang, B Wang, Y Zhang, J Hong, Y Zhang, W Wang, W Gu
Endocrine 2013
Assessment of insulin action on carbohydrate metabolism: physiological and non-physiological methods
S Dube, I Errazuriz, C Cobelli, R Basu, A Basu
Diabetic Medicine 2013
Modified minimal model for effect of physical exercise on insulin sensitivity and glucose effectiveness in type 2 diabetes and healthy human
A Kartono
Theory in Biosciences 2013
Dietary conjugated α-linolenic acid did not improve glucose tolerance in a neonatal pig model
CA Castellano, JP Baillargeon, M Plourde, SI Briand, P Angers, A Giguère, JJ Matte
European Journal of Nutrition 2013
Associations of β -Cell Function and Insulin Resistance with Youth-Onset Type 2 Diabetes and Prediabetes Among Asian Indians
V Mohan, A Amutha, H Ranjani, R Unnikrishnan, M Datta, RM Anjana, L Staimez, MK Ali, KM Narayan
Diabetes Technology & Therapeutics 2013
Regulation of Insulin Secretion in Human Pancreatic Islets
P Rorsman, M Braun
Annual Review of Physiology 2013
Maternal taurine supplementation in rats partially prevents the adverse effects of early-life protein deprivation on  -cell function and insulin sensitivity
C Tang, K Marchand, L Lam, V Lux-Lantos, SM Thyssen, J Guo, A Giacca, E Arany
Reproduction 2013
Insulin resistance and fasting plasma glucose in first degree relatives of patients with type 1 diabetes
K Siewko, A Popławska-Kita, B Telejko, R Maciulewski, A Zielińska, A Nikołajuk, M Górska, M Szelachowska
Journal of Diabetes and its Complications 2013
The impact of mathematical modeling on the understanding of diabetes and related complications
I Ajmera, M Swat, C Laibe, NL Novère, V Chelliah
CPT Pharmacometrics Syst. Pharmacol. 2013
The use of reinforcement learning algorithms to meet the challenges of an artificial pancreas
MK Bothe, L Dickens, K Reichel, A Tellmann, B Ellger, M Westphal, AA Faisal
Expert Review of Medical Devices 2013
Design of Optimal Self-Regulation Mamdani-Type Fuzzy Inference Controller for Type I Diabetes Mellitus
DN Abadi, MH Khooban, A Alfi, M Siahi
Arabian Journal for Science and Engineering 2013
Can new-onset diabetes after kidney transplant be prevented?
HA Chakkera, EJ Weil, PT Pham, J Pomeroy, WC Knowler
Diabetes care 2013
The Design and Conduct of a Community-Based Registry and Biorepository: A Focus on Cardiometabolic Health in Latinos: Arizona Insulin Resistance Registry and Repository
GQ Shaibi, DK Coletta, V Vital, LJ Mandarino
Clinical and Translational Science 2013
Linking neuronal brain activity to the glucose metabolism
B Göbel, KM Oltmanns, M Chung
Theoretical Biology and Medical Modelling 2013
Effects of intravenous lipopolysaccharide infusion on glucose and insulin dynamics in horses with equine metabolic syndrome
EM Tadros, N Frank, FG de Witte, RC Boston
American Journal of Veterinary Research 2013
DPP-4 Inhibitors as a New Option for the Management of Type 2 Diabetes
SA Lee
Journal of Korean Diabetes 2013
Model-based sensor-augmented pump therapy
B Grosman, G Voskanyan, M Loutseiko, A Roy, A Mehta, N Kurtz, N Parikh, FR Kaufman, JJ Mastrototaro, B Keenan
Journal of diabetes science and technology 2013
Clinical implications and economic impact of accuracy differences among commercially available blood glucose monitoring systems
ES Budiman, N Samant, A Resch
Journal of diabetes science and technology 2013
One-hour glucose during an oral glucose challenge prospectively predicts β-cell deterioration and prediabetes in obese Hispanic youth
JY Kim, MI Goran, CM Toledo-Corral, MJ Weigensberg, M Choi, GQ Shaibi
Diabetes care 2013
Evidence of Reduced  -Cell Function in Asian Indians With Mild Dysglycemia
LR Staimez, MB Weber, H Ranjani, MK Ali, JB Echouffo-Tcheugui, LS Phillips, V Mohan, KM Narayan
Diabetes care 2013
Co-occurrence of Risk Alleles in or Near Genes Modulating Insulin Secretion Predisposes Obese Youth to Prediabetes
C Giannini, CD Man, L Groop, C Cobelli, H Zhao, MM Shaw, E Duran, B Pierpont, AE Bale, S Caprio, N Santoro
Diabetes care 2013
Combined Heart Rate- and Accelerometer-Assessed Physical Activity Energy Expenditure and Associations With Glucose Homeostasis Markers in a Population at High Risk of Developing Diabetes: The ADDITION-PRO study
AL Hansen, B Carstensen, JW Helge, NB Johansen, B Gram, JS Christiansen, S Brage, T Lauritzen, ME Jorgensen, M Aadahl, DR Witte
Diabetes care 2013
Model-Based Sensor-Augmented Pump Therapy
B Grosman, G Voskanyan, M Loutseiko, A Roy, A Mehta, N Kurtz, N Parikh, FR Kaufman, JJ Mastrototaro, B Keenan
Journal of diabetes science and technology 2013
Clinical Implications and Economic Impact of Accuracy Differences among Commercially Available Blood Glucose Monitoring Systems
ES Budiman, N Samant, A Resch
Journal of diabetes science and technology 2013
One-Hour Glucose During an Oral Glucose Challenge Prospectively Predicts β-Cell Deterioration and Prediabetes in Obese Hispanic Youth
JY Kim, MI Goran, CM Toledo-Corral, MJ Weigensberg, M Choi, GQ Shaibi
Diabetes care 2013
Measuring β-Cell Function Relative to Insulin Sensitivity in Youth
L Sjaarda, SJ Lee, H Tfayli, F Bacha, M Bertolet, S Arslanian
Diabetes care 2013
The artificial pancreas: is it important to understand how the β cell controls blood glucose?
GM Steil, GM Grodsky
Journal of diabetes science and technology 2013
Fuzzy Logic Strategy for Solving an Optimal Control Problem of Glucose and Insulin in Diabetic Human
JM Ntaganda
Open Journal of Applied Sciences 2013
Comparison of Oral and Intravenous Glucose Tolerance Test Derived Sensitivity and Secretory Indices in Obese Adolescents
PC Brar, D Koren, PR Gallagher, B Pendurthi, LE Katz
Clinical Pediatrics 2013
Exogenous Glucose Administration Impairs Glucose Tolerance and Pancreatic Insulin Secretion during Acute Sepsis in Non-Diabetic Mice
Y Watanabe, S Singamsetty, B Zou, L Guo, D Stefanovski, LC Alonso, A Garcia-Ocana, CP ODonnell, BJ McVerry, CC Caldwell
PloS one 2013
Overexpression of glutathione peroxidase 4 prevents β-cell dysfunction induced by prolonged elevation of lipids in vivo
K Koulajian, A Ivovic, K Ye, T Desai, A Shah, IG Fantus, Q Ran, A Giacca
American journal of physiology. Endocrinology and metabolism 2013
A novel approach to monitor glucose metabolism using stable isotopically labelled glucose in longitudinal studies in mice
TH van Dijk, AJ Laskewitz, A Grefhorst, TS Boer, VW Bloks, F Kuipers, AK Groen, DJ Reijngoud
Laboratory Animals 2013
Simultaneous Measurement of Insulin Sensitivity, Insulin Secretion, and the Disposition Index in Conscious Unhandled Mice
LC Alonso, Y Watanabe, D Stefanovski, EJ Lee, S Singamsetty, LC Romano, B Zou, A Garcia-Ocaña, RN Bergman, CP O'Donnell
Obesity 2012
PCOS is associated with increased CD11c expression and crown-like structures in adipose tissue and increased central abdominal fat depots independent of obesity
ZH Huang, B Manickam, V Ryvkin, XJ Zhou, G Fantuzzi, T Mazzone, S Sam
The Journal of clinical endocrinology and metabolism 2012
Association of Fibrillin-3 and Transcription Factor-7-Like 2 Gene Variants With Metabolic Phenotypes in PCOS
SK Yalamanchi, S Sam, MO Cardenas, LW Holaday, M Urbanek, A Dunaif
Obesity 2012
Effects of Bariatric Surgery on Glucose Homeostasis and Type 2 Diabetes
D Bradley, F Magkos, S Klein
Gastroenterology 2012
Genetics of glucose homeostasis: implications for insulin resistance and metabolic syndrome
JM Norris, SS Rich
Arteriosclerosis, thrombosis, and vascular biology 2012
Associations among Body Mass Index, Insulin Resistance, and Pancreatic β-Cell Function in Korean Patients with New-Onset Type 2 Diabetes
JO Chung, DH Cho, DJ Chung, MY Chung
The Korean Journal of Internal Medicine 2012
Optimal homeostasis necessitates bistable control
G Wang
Journal of The Royal Society Interface 2012
ISMRM workshop on fat-water separation: Insights, applications and progress in MRI
HH Hu, P Börnert, D Hernando, P Kellman, J Ma, S Reeder, C Sirlin
Magnetic Resonance in Medicine 2012
Insulin sensitivity is associated with thigh adipose tissue distribution in healthy postmenopausal women
AM Goss, BA Gower
Metabolism 2012
Impact of Family History of Diabetes on β -Cell Function and Insulin Resistance Among Chinese with Normal Glucose Tolerance
G Chen, M Li, Y Xu, N Chen, H Huang, J Liang, L Li, J Wen, L Lin, J Yao
Diabetes Technology & Therapeutics 2012
Role of Adipokines and Other Inflammatory Mediators in Gestational Diabetes Mellitus and Previous Gestational Diabetes Mellitus
N Vrachnis, P Belitsos, S Sifakis, K Dafopoulos, C Siristatidis, KI Pappa, Z Iliodromiti
International Journal of Endocrinology 2012
Modeling the Autonomic and Metabolic Effects of Obstructive Sleep Apnea: A Simulation Study
L Cheng, MC Khoo
Frontiers in physiology 2012
Time-dependent changes in glucose and insulin regulation during intermittent hypoxia and continuous hypoxia
EJ Lee, LC Alonso, D Stefanovski, HC Strollo, LC Romano, B Zou, S Singamsetty, KA Yester, KR McGaffin, A Garcia-Ocana, CP O’Donnell
European Journal of Applied Physiology 2012
A concerted decline in insulin secretion and action occurs across the spectrum of fasting and postchallenge glucose concentrations : Insulin secretion and action in prediabetes
A Sathananthan, CD Man, AR Zinsmeister, M Camilleri, RJ Rodeheffer, G Toffolo, C Cobelli, RA Rizza, A Vella
Clinical Endocrinology 2012
Risk factors for type 2 diabetes: Lessons learned from Japanese Americans in Seattle : Type 2 diabetes in Japanese Americans
WY Fujimoto, EJ Boyko, T Hayashi, SE Kahn, DL Leonetti, MJ McNeely, WP Shuman
Journal of Diabetes Investigation 2012
Experimental Design for Biological Systems
M Chung, E Haber
SIAM Journal on Control and Optimization 2012
β-Cell Dysfunction and the Onset of Type 2 Diabetes
I Fennoy
The Journal of Pediatrics 2012
A feedback glucose control strategy for type II diabetes mellitus based on fuzzy logic
F Ekram, L Sun, O Vahidi, E Kwok, RB Gopaluni
The Canadian Journal of Chemical Engineering 2012
Impact of Family History of Diabetes on <i>β</i>-Cell Function and Insulin Resistance Among Chinese with Normal Glucose Tolerance
G Chen, M Li, Y Xu, N Chen, H Huang, J Liang, L Li, J Wen, L Lin, J Yao
Diabetes Technology & Therapeutics 2012
The Oral Disposition Index: A Valuable Estimate of β-Cell Function in Obese Youth
S Caprio
The Journal of Pediatrics 2012
Prediction of postprandial blood glucose under uncertainty and intra-patient variability in type 1 diabetes: A comparative study of three interval models
M García-Jaramillo, R Calm, J Bondia, J Vehí
Computer Methods and Programs in Biomedicine 2012
On the use of continuous glucose monitoring systems to design optimal clinical tests for the identification of type 1 diabetes models
F Galvanin, M Barolo, F Bezzo
Computer Methods and Programs in Biomedicine 2012
Mechanistic systems modeling to guide drug discovery and development
BJ Schmidt, JA Papin, CJ Musante
Drug Discovery Today 2012
Circadian Rhythms, Metabolism, and Insulin Sensitivity: Transcriptional Networks in Animal Models
M Kitazawa
Current Diabetes Reports 2012
Effects of Ω-3 (n-3) Fatty Acid Supplementation on Insulin Sensitivity in Horses
TM Hess, J Rexford, DK Hansen, NS Ahrens, M Harris, T Engle, T Ross, KG Allen
Journal of Equine Veterinary Science 2012
Blood glucose control algorithms for type 1 diabetic patients: A methodological review
K Lunze, T Singh, M Walter, MD Brendel, S Leonhardt
Biomedical Signal Processing and Control 2012
A simulation study on optimal IMC based PI/PID controller for mean arterial blood pressure
S Saxena, YV Hote
Biomedical Engineering Letters 2012
The effect of age and exercise training on insulin sensitivity, fat and muscle tissue cytokine profiles and body composition of old and young Standardbred mares
NR Liburt, MN Fugaro, K Malinowski, EK Wunderlich, JL Zambito, DW Horohov, A Betancourt, RC Boston, RJ Geor, J Onishi, KH McKeever
Comparative Exercise Physiology 2012
Métabolisme des glucides et méthodes d’exploration chez l’homme
F Andreelli
EMC - Endocrinologie - Nutrition 2012
Early maternal undernutrition programs increased feed intake, altered glucose metabolism and insulin secretion, and liver function in aged female offspring
LA George, L Zhang, N Tuersunjiang, Y Ma, NM Long, AB Uthlaut, DT Smith, PW Nathanielsz, SP Ford
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2012
Risk Factors for Type 2 Diabetes: Lessons Learned from Japanese Americans in Seattle
WY Fujimoto, EJ Boyko, T Hayashi, SE Kahn, DL Leonetti, MJ McNeely, WP Shuman
Journal of Diabetes Investigation 2012
Altered glucose disposition and insulin sensitivity in peri-pubertal first-degree relatives of women with polycystic ovary syndrome
N Raissouni, A Kolesnikov, R Purushothaman, S Sinha, S Bhandari, A Bhangoo, S Malik, R Mathew, JP Baillargeon, MI Hernandez, M Rosenbaum, S Ten, D Geller
International Journal of Pediatric Endocrinology 2012
A concerted decline in insulin secretion and action occurs across the spectrum of fasting and postchallenge glucose concentrations
A Sathananthan, CD Man, AR Zinsmeister, M Camilleri, RJ Rodeheffer, G Toffolo, C Cobelli, RA Rizza, A Vella
Clinical Endocrinology 2012
Mathematical model for glucose regulation in the whole-body system
H Kang, K Han, MY Choi
Islets 2012
Knowledge-based Closed-loop Control of Blood Glucose Concentration in Diabetic Patients and Comparison with H ∞ Control Technique
S Yasini, A Karimpour, MB Sistani
IETE Journal of Research 2012
Real-time state estimation and long-term model adaptation: a two-sided approach toward personalized diagnosis of glucose and insulin levels
C Eberle, C Ament
Journal of diabetes science and technology 2012
The identifiable virtual patient model: comparison of simulation and clinical closed-loop study results
SS Kanderian, SA Weinzimer, GM Steil
Journal of diabetes science and technology 2012
Measuring β-cell function relative to insulin sensitivity in youth: does the hyperglycemic clamp suffice?
L Sjaarda, SJ Lee, H Tfayli, F Bacha, M Bertolet, S Arslanian
Diabetes care 2012
PANCREATIC β-CELL DYSFUNCTION IN POLYCYSTIC OVARY SYNDROME: THE ROLE OF METFORMIN
C Messer, R Boston, D Leroith, E Geer, JD Miller, M Messer, W Futterweit
Endocrine Practice 2012
A Strategy for Development of Realistic Mathematical Models of Whole-Body Metabolism
MF Madsen, S Dano, B Quistorff
Open Journal of Applied Sciences 2012
Overnight Control of Blood Glucose in People with Type 1 Diabetes
D Boiroux, AK Duun-Henriksen, S Schmidt, K Nørgaard, S Madsbad, O Skyggebjerg, PR Jensen, NK Poulsen, H Madsen, JB Jørgensen
IFAC Proceedings Volumes 2012
A Novel Multi-Objective Optimization based Experimental Design and its Application for Physiological Model of Type 1 Diabetes
V Maheshwari, GP Rangaiah, L Samavedham
IFAC Proceedings Volumes 2012
Nonlinear analysis of Type 1 Diabetes Models by Differential Geometric Approach
P Szalay, PI Sas, L Barkai, L Kovács
IFAC Proceedings Volumes 2012
Improving Minimal Model Identifiability in Insulin Resistant Patients Utilizing Insight from the Graphical Structural Model Identifiability Method
PD Docherty, JG Chase
IFAC Proceedings Volumes 2012
Insulin Resistance and the Polycystic Ovary Syndrome Revisited: An Update on Mechanisms and Implications
E Diamanti-Kandarakis, A Dunaif
Endocrine reviews 2012
Aerobic exercise training conserves insulin sensitivity for 1 yr following weight loss in overweight women
G Fisher, GR Hunter, BA Gower
Journal of applied physiology 2012
Early maternal undernutrition programs increased feed intake, altered glucose metabolism and insulin secretion, and liver function in aged female offspring
LA George, L Zhang, N Tuersunjiang, Y Ma, NM Long, AB Uthlaut, DT Smith, PW Nathanielsz, SP Ford
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2012
The disposition index: from individual to population approach
P Denti, GM Toffolo, C Cobelli
American journal of physiology. Endocrinology and metabolism 2012
Early Origins of the Metabolic Syndrome: Role of Small Size at Birth, Early Postnatal Weight Gain, and Adult IGF-I
GF Kerkhof, RW Leunissen, AC Hokken-Koelega
The Journal of clinical endocrinology and metabolism 2012
Technologies and Protocols for the Future of Internet Design: Reinventing the Web
DP Vidyarthi
2012
Health Profile of Young Adults Born Preterm: Negative Effects of Rapid Weight Gain in Early Life
GF Kerkhof, RH Willemsen, RW Leunissen, PE Breukhoven, AC Hokken-Koelega
The Journal of clinical endocrinology and metabolism 2012
Introduction to Modeling Biological Cellular Control Systems
W Liu
2012
Computational Science and Its Applications – ICCSA 2012
B Murgante, O Gervasi, S Misra, N Nedjah, AM Rocha, D Taniar, BO Apduhan
2012
Insulin dynamics in obesity and diabetes
Susumu Seino, Tadao Shibasaki, Kohtaro Minami
Journal of Clinical Investigation 2011
Type 2 diabetes mellitus: a disease of the governance of the glucose-insulin system: an experimental metabolic control analysis study
M Trombetta, L Boselli, A Cretti, A Calì, M Vettore, B Caruso, R Dorizzi, A Avogaro, M Muggeo, E Bonora, RC Bonadonna
Nutrition, Metabolism, and Cardiovascular Diseases 2011
Consistency of the disposition index in the face of diet induced insulin resistance: potential role of FFA
D Stefanovski, JM Richey, O Woolcott, M Lottati, D Zheng, LN Harrison, V Ionut, SP Kim, I Hsu, RN Bergman
PloS one 2011
The Metabolic Syndrome
S Devaraj, D Siegel, I Jialal
The Metabolic Syndrome 2011
Dynamic modeling of methylprednisolone effects on body weight and glucose regulation in rats
J Fang, DC DuBois, Y He, RR Almon, WJ Jusko
Journal of Pharmacokinetics and Pharmacodynamics 2011
Progress in Molecular Biology and Translational Science
JF Wilkins, F Úbeda
Modifications of Nuclear DNA and its Regulatory Proteins 2011
Computer Aided Chemical Engineering
A Bock, G François, T Prud'homme, D Gillet
21st European Symposium on Computer Aided Process Engineering 2011
Inherited destiny? Genetics and gestational diabetes mellitus
RM Watanabe
Genome Medicine 2011
Comparison of optimal design methods in inverse problems
HT Banks, K Holm, F Kappel
Inverse Problems 2011
Effects of a supplement containing chromium and magnesium on morphometric measurements, resting glucose, insulin concentrations and insulin sensitivity in laminitic obese horses
KA Chameroy, N Frank, SB Elliott, RC Boston
Equine Veterinary Journal 2011
Developing a physiological model for type II diabetes mellitus
O Vahidi, KE Kwok, RB Gopaluni, L Sun
Biochemical Engineering Journal 2011
Using a fuzzy controller optimized by a genetic algorithm to regulate blood glucose level in type 1 diabetes
F Fereydouneyan, A Zare, N Mehrshad
Journal of Medical Engineering & Technology 2011
Misclassification of subjects with insulin resistance and associated cardiovascular risk factors by homeostasis model assessment index. Utility of a postprandial method based on oral glucose tolerance test
S Martinez-Hervas, C Argente, J Garcia-Jodar, A Priego, JT Real, A Carratala, R Carmena, JF Ascaso
Metabolism 2011
Induced L2-norm minimization of glucose–insulin system for Type I diabetic patients
L Kovács, B Benyó, J Bokor, Z Benyó
Computer Methods and Programs in Biomedicine 2011
A physiological Intensive Control Insulin-Nutrition-Glucose (ICING) model validated in critically ill patients
J Lin, NN Razak, CG Pretty, AL Compte, P Docherty, JD Parente, GM Shaw, CE Hann, JG Chase
Computer Methods and Programs in Biomedicine 2011
Deterioration in cardiometabolic risk markers in obese women during depot medroxyprogesterone acetate use
P Segall-Gutierrez, AH Xiang, RM Watanabe, E Trigo, FZ Stanczyk, X Liu, R Jurow, TA Buchanan
Contraception 2011
Multi-Parametric Model-Based Control
P Dua, EN Pistikopoulos
Multi-Parametric Model-Based Control 2011
Dynamical analysis in the mathematical modelling of human blood glucose
S Bae, B Kang
International Journal of Mathematical Education in Science and Technology 2011
Magnesium improves the beta-cell function to compensate variation of insulin sensitivity: double-blind, randomized clinical trial
F Guerrero-Romero, M Rodríguez-Morán
European Journal of Clinical Investigation 2011
Web based prediction for diabetes treatment
L Grandinetti, O Pisacane
Future Generation Computer Systems 2011
Glucose and insulin dynamics associated with continuous rate infusion of dextrose solution or dextrose solution and insulin in healthy and endotoxin-exposed horses
JH Han, HC McKenzie, LJ McCutcheon, RJ Geor
American Journal of Veterinary Research 2011
Glucose level regulation via integral high-order sliding modes
L Dorel
Mathematical Biosciences and Engineering 2011
Type 2 diabetes mellitus: A disease of the governance of the glucose-insulin system
M Trombetta, L Boselli, A Cretti, A Calì, M Vettore, B Caruso, R Dorizzi, A Avogaro, M Muggeo, E Bonora
Nutrition Metabolism and Cardiovascular Diseases 2011
Increment of 30-min post-challenge plasma glucose is associated with urine albumin excretion in men with normal glucose regulation : Increment of 30-min post-challenge glucose and albumin/creatinine ratio
D Li, X Hou, X Ma, W Zong, X Shao, H Lu, K Xiang, W Jia
Diabetic Medicine 2011
Dynamics of insulin action in hypertension: assessment from minimal model interpretation of intravenous glucose tolerance test data
R Burattini, M Morettini, FD Nardo, M Boemi
Medical & Biological Engineering & Computing 2011
Measurement of insulin action: a tribute to Sir Harold Himsworth : Measurement of insulin action
SH Kim
Diabetic Medicine 2011
Identifiability and online estimation of diagnostic parameters in the glucose insulin homeostasis
C Eberle, C Ament
Biosystems 2011
Comparison of control algorithms for the blood glucose concentration in a virtual patient with an artificial pancreas
E Semizer, M Yüceer, İ Atasoy, R Berber
Chemical Engineering Research and Design 2011
Pancreatic iron and glucose dysregulation in thalassemia major
LJ Noetzli, SD Mittelman, RM Watanabe, TD Coates, JC Wood
American Journal of Hematology 2011
Observer-Based State Feedback for Enhanced Insulin Control of Type ‘I’ Diabetic Patients
A Hariri, LY Wang
The open biomedical engineering journal 2011
A 90-day adaptation to a high glycaemic diet alters postprandial lipid metabolism in non-obese horses without affecting peripheral insulin sensitivity : High glycaemic diets fed to non-obese horses
JK Suagee, BA Corl, KL Swyers, TL Smith, CD Flinn, RJ Geor
Journal of Animal Physiology and Animal Nutrition 2011
Association between an increment of 30-minute postchallenge plasma glucose and urine albumin excretion exists in postmenopausal women but not in premenopausal women :
D Li, X Hou, X Ma, W Zong, H Lu, K Xiang, W Jia
Menopause 2011
HOMA-IR and Its Association with Metabolic Risk Factors among Korean Adolescents
E Seo, SG Lee, SH Kim, MJ Park
Korean Journal of Pediatric Gastroenterology and Nutrition 2011
Both sitagliptin analogue &amp; pioglitazone preserve the β-cell proportion in the islets with different mechanism in non-obese and obese diabetic mice
JA Yeom, ES Kim, HS Park, DS Ham, CL Sun, JW Kim, JH Cho, KH Yoon
BMB Reports 2011
Hyperbolic correlation between insulin sensitivity and insulin secretion fades away in lean subjects with superb glucose regulation
T Aizawa, M Yamada, M Katakura, Y Funase, K Yamashita, K Yamauchi
Endocrine Journal 2011
Williams Textbook of Endocrinology
DW Cooke, SA Divall, S Radovick
Williams Textbook of Endocrinology 2011
Review and Analysis of Blood Glucose (BG) Models for Type 1 Diabetic Patients
NP Balakrishnan, GP Rangaiah, L Samavedham
Industrial & engineering chemistry research 2011
Increment of 30-min post-challenge plasma glucose is associated with urine albumin excretion in men with normal glucose regulation: Increment of 30-min post-challenge glucose and albumin/creatinine ratio
D Li, X Hou, X Ma, W Zong, X Shao, H Lu, K Xiang, W Jia
Diabetic Medicine 2011
Measurement of insulin action: a tribute to Sir Harold Himsworth: Measurement of insulin action
SH Kim
Diabetic Medicine 2011
How can we measure insulin sensitivity/resistance?
B Antuna-Puente, E Disse, R Rabasa-Lhoret, M Laville, J Capeau, JP Bastard
Diabetes & Metabolism 2011
Multi-Parametric Model-Based Control: Volume 2: Theory and Applications
P Dua, EN Pistikopoulos
Multi-Parametric Model-Based Control: Volume 2: Theory and Applications 2011
A 90-day adaptation to a high glycaemic diet alters postprandial lipid metabolism in non-obese horses without affecting peripheral insulin sensitivity: High glycaemic diets fed to non-obese horses
JK Suagee, BA Corl, KL Swyers, TL Smith, CD Flinn, RJ Geor
Journal of Animal Physiology and Animal Nutrition 2011
Magnesium improves the beta-cell function to compensate variation of insulin sensitivity: double-blind, randomized clinical trial: MAGNESIUM AND BETA-CELL FUNCTION
F Guerrero-Romero, M Rodríguez-Morán
European Journal of Clinical Investigation 2011
The Unscented Kalman Filter estimates the plasma insulin from glucose measurement
C Eberle, C Ament
Biosystems 2011
Both sitagliptin analogue & pioglitazone preserve the β-cell proportion in the islets with different mechanism in non-obese and obese diabetic mice
JA Yeom, ES Kim, HS Park, DS Ham, CL Sun, JW Kim, JH Cho, KH Yoon
BMB Reports 2011
A switching control strategy for the attenuation of blood glucose disturbances
MG Markakis, GD Mitsis, GP Papavassilopoulos, PA Ioannou, VZ Marmarelis
Optimal Control Applications and Methods 2011
Safe glycemic management during closed-loop treatment of type 1 diabetes: the role of glucagon, use of multiple sensors, and compensation for stress hyperglycemia
WK Ward, JR Castle, JE Youssef
Journal of diabetes science and technology 2011
Short-Term Intensive Therapy in Newly Diagnosed Type 2 Diabetes Partially Restores Both Insulin Sensitivity and  -Cell Function in Subjects With Long-Term Remission
Y Hu, L Li, Y Xu, T Yu, G Tong, H Huang, Y Bi, J Weng, D Zhu
Diabetes care 2011
Fasting Indicators of Insulin Sensitivity: Effects of Ethnicity and Pubertal Status
TC Adam, RE Hasson, CJ Lane, JN Davis, MJ Weigensberg, D Spruijt-Metz, MI Goran
Diabetes care 2011
Identification and low-complexity regime-switching insulin control of type I diabetic patients
A Hariri, LY Wang
Journal of Biomedical Science and Engineering 2011
Computational evaluation of the dynamic minimal model for the root causes of hypoglycemia
M Tunç, S Şişbot, AK Gülkaya
Journal of Biomedical Science and Engineering 2011
Quasi Model Based Optimal Control of Type 1 Diabetes Mellitus*
A György, P Szalay, DA Drexler, B Benyó, Z Benyó, L Kovács
IFAC Proceedings Volumes 2011
Nonlinear Control Analysis of an ICU Model for Tight Glycaemic Control
L Kovács, P Szalay, B Benyó, JG Chase
IFAC Proceedings Volumes 2011
Robust Tight Glycaemic Control of ICU patients
L Kovács, P Szalay, B Benyó, JG Chase
IFAC Proceedings Volumes 2011
Strategies for Glucose Control in People with Type 1 Diabetes
D Boiroux, DA Finan, JB Jørgensen, NK Poulsen, H Madsen
IFAC Proceedings Volumes 2011
Disruption of Circadian Rhythms Accelerates Development of Diabetes through Pancreatic Beta-Cell Loss and Dysfunction
JE Gale, HI Cox, J Qian, GD Block, CS Colwell, AV Matveyenko
Journal of Biological Rhythms 2011
Artificial Intelligence in Medicine
M Peleg, N Lavrač, C Combi
Artificial Intelligence in Medicine 2011
Dietary supplementation with short-chain fructo-oligosaccharides improves insulin sensitivity in obese horses1
F Respondek, K Myers, TL Smith, A Wagner, RJ Geor
Journal of animal science 2011
Advances in Systems Biology
II Goryanin, AB Goryachev
2011
Lipid-induced pancreatic  -cell dysfunction: focus on in vivo studies
A Giacca, C Xiao, AI Oprescu, AC Carpentier, GF Lewis
American journal of physiology. Endocrinology and metabolism 2010
Impact of Acute Biochemical Castration on Insulin Sensitivity in Healthy Adult Men
A Rabiee, AA Dwyer, LM Caronia, FJ Hayes, MA Yialamas, DK Andersen, B Thomas, M Torriani, D Elahi
Endocrine Research 2010
Disease Gene Identification
JK DiStefano
2010
Disease Gene Identification
JK DiStefano
2010
Disease Gene Identification
JK DiStefano
2010
Different levels of overnutrition and weight gain during pregnancy have differential effects on fetal growth and organ development
LA George, AB Uthlaut, NM Long, L Zhang, Y Ma, DT Smith, PW Nathanielsz, SP Ford
Reproductive biology and endocrinology : RB&E 2010
Measuring and estimating insulin resistance in clinical and research settings
M Matsuda
Nutrition, Metabolism and Cardiovascular Diseases 2010
Glucose metabolism parameters during an oral glucose tolerance test in patients with autosomal dominant polycystic kidney disease
M Pietrzak-Nowacka, K Safranow, E Byra, M Nowosiad, M Marchelek-Myśliwiec, K Ciechanowski
Scandinavian Journal of Clinical & Laboratory Investigation 2010
Insulin sensitivity (Si) assessment in lean and overweight subjects using two different protocols and updated software
A Borai, C Livingstone, S Shafi, H Zarif, G Ferns
Scandinavian Journal of Clinical & Laboratory Investigation 2010
Glucose effectiveness and insulin sensitivity measurements derived from the non-insulin-assisted minimal model and the clamp techniques are concordant
JE Henriksen, F Alford, G Ward, P Thye-Rønn, K Levin, O Hother-Nielsen, C Rantzau, R Boston, H Beck-Nielsen
Diabetes/Metabolism Research and Reviews 2010
Exercise in aging: its important role in mortality, obesity and insulin resistance
AS Ryan
Aging Health 2010
Differences emerge in visceral adipose tissue accumulation after selection for innate cardiovascular fitness
DW Brock, BA Irving, B Gower, GR Hunter
International Journal of Obesity 2010
Vitamin D intake is associated with insulin sensitivity in African American, but not European American, women
JA Alvarez, NC Bush, SS Choquette, GR Hunter, BE Darnell, RA Oster, BA Gower
Nutrition & Metabolism 2010
Systems engineering medicine: engineering the inflammation response to infectious and traumatic challenges
RS Parker, G Clermont
Journal of the Royal Society, Interface / the Royal Society 2010
Systemic investigation of a brain-centered model of the human energy metabolism
B Göbel, D Langemann
Theory in Biosciences 2010
Reply to Dr. Retnakaran
Y Saisho, K Miyakoshi, T Abe
Endocrine Journal 2010
Preservation of Beta-Cell Function in Type 2 Diabetes
K Nyalakonda, T Sharma, F Ismail-Beigi
Endocrine Practice 2010
Robust servo control of a novel type 1 diabetic model
L Kovács, B Kulcsár, A György, Z Benyó
Optimal Control Applications and Methods 2010
The first and second phase of insulin secretion in naive Chinese type 2 diabetes mellitus
JD Lin, TL Hsia, CZ Wu, CC Su, WY Ma, AT Hsieh, CH Hsieh, K Wang, YM Chu, D Pei
Metabolism 2010
Growth patterns during childhood and the relationship with acylation-stimulating protein
RW Leunissen, Y Gao, K Cianflone, T Stijnen, AC Hokken-Koelega
Clinical Endocrinology 2010
Compact energy metabolism model: Brain controlled energy supply
B Göbel, D Langemann, KM Oltmanns, M Chung
Journal of Theoretical Biology 2010
Theoretical blood glucose control in hyper- and hypoglycemic and exercise scenarios by means of an algorithm
G Quiroz, R Femat
Journal of Theoretical Biology 2010
Population analysis of ethnicity and first-phase insulin release
L Xie, RP Hoffman, P Veng-Pedersen
Diabetes Research and Clinical Practice 2010
Blood glucose regulation with stochastic optimal control for insulin-dependent diabetic patients
SU Acikgoz, UM Diwekar
Chemical Engineering Science 2010
Relationship between Insulin Sensitivity and Muscle Lipids may Differ with Muscle Group and Ethnicity
JC Lawrence, BA Gower, WT Garvey, AJ Muñoz, BE Darnell, RA Oster, SD Buchthal, MI Goran, BR Newcomer
The Open Obesity Journal 2010
OBSTRUCTIVE SLEEP APNEA AND METABOLIC DYSFUNCTION IN POLYCYSTIC OVARY SYNDROME
K Nitsche, DA Ehrmann
Best practice & research. Clinical endocrinology & metabolism 2010
Textbook of Diabetes: Holt/Textbook of Diabetes
HE Larsson, AJ Delli, SA Ivarsson, Å Lernmark
Textbook of Diabetes: Holt/Textbook of Diabetes 2010
Effects of a supplement containing chromium and magnesium on morphometric measurements, resting glucose, insulin concentrations and insulin sensitivity in laminitic obese horses: Chromium and magnesium in obese insulin-resistant horses
KA Chameroy, N Frank, SB Elliott, RC Boston
Equine Veterinary Journal 2010
Glycemic Index and Glucose Utilization of Rice Vermicelli in Healthy Subjects
S Sato, K Fukumura, A Nishiyama, I Kanamoto, Y Inoue, T Konishi
Biological & Pharmaceutical Bulletin 2010
Growth patterns during childhood and the relationship with acylation-stimulating protein: Acylation-stimulating protein and growth
RW Leunissen, Y Gao, K Cianflone, T Stijnen, AC Hokken-Koelega
Clinical Endocrinology 2010
A fast generalizable solution method for glucose control algorithms
CE Hann, P Docherty, JG Chase, GM Shaw
Mathematical Biosciences 2010
Factors Influencing the Effectiveness of Glucagon for Preventing Hypoglycemia
JR Castle, JM Engle, JE Youssef, RG Massoud, WK Ward
Journal of diabetes science and technology 2010
Ethnicity-specific anthropometric predictors of metabolic risk in women
NC Bush, JA Alvarez, GR Hunter, DW Brock, PC Chandler-Laney, BA Gower
International journal of body composition research 2010
Modeling the Effects of Subcutaneous Insulin Administration and Carbohydrate Consumption on Blood Glucose
MW Percival, WC Bevier, Y Wang, E Dassau, HC Zisser, L Jovanovič, FJ 3rd
Journal of diabetes science and technology 2010
ANALYSIS OF GLUCOSE REGULATION USING FUZZY CLUSTERING BASED PIECEWISE AFFINE APPROXIMATION APPROACH
S Ghosh, S Maka
Journal of Biological Systems 2010
Cortisol is negatively associated with insulin sensitivity in overweight Latino youth
TC Adam, RE Hasson, EE Ventura, C Toledo-Corral, KA Le, S Mahurkar, CJ Lane, MJ Weigensberg, MI Goran
The Journal of clinical endocrinology and metabolism 2010
The disposition index: adjustment for peripheral vs. hepatic insulin sensitivity?: The disposition index
K Faerch, C Brøns, AC Alibegovic, A Vaag
The Journal of Physiology 2010
Quest for the Artificial Pancreas: Combining Technology with Treatment
RA Harvey, Y Wang, B Grosman, MW Percival, W Bevier, DA Finan, H Zisser, DE Seborg, L Jovanovic, FJ Doyle, E Dassau
IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society 2010
Computational Model for Studying the Analogies Between Endocrine Systems of Humans and Rats with Diabetes Mellitus. Experimental and Simulated Results.*
G Campetelli, M Lupo, BL Fina, DA Zumoffen, MS Basualdo, A Rigalli
IFAC Proceedings Volumes 2010
Novel canine models of obese prediabetes and mild type 2 diabetes
V Ionut, H Liu, V Mooradian, AV Castro, M Kabir, D Stefanovski, D Zheng, EL Kirkman, RN Bergman
American journal of physiology. Endocrinology and metabolism 2010
IVGTT glucose minimal model covariate selection by nonlinear mixed-effects approach
P Denti, A Bertoldo, P Vicini, C Cobelli
American journal of physiology. Endocrinology and metabolism 2010
Maternal obesity and increased nutrient intake before and during gestation in the ewe results in altered growth, adiposity, and glucose tolerance in adult offspring1
NM Long, LA George, AB Uthlaut, DT Smith, MJ Nijland, PW Nathanielsz, SP Ford
Journal of animal science 2010
Gestational Diabetes During and After Pregnancy
C Kim, A Ferrara
2010
Correction of insulin sensitivity and glucose disposal after pancreatic islet transplantation: preliminary results
D Hirsch, J Odorico, N Radke, M Hanson, JS Danobeitia, D Hullett, R Alejandro, C Ricordi, LA Fernandez
Diabetes, obesity & metabolism 2010
Handbook on Decision Making
LC Jain, CP Lim
2010
BetaSys
B Booß-Bavnbek, B Klösgen, J Larsen, F Pociot, E Renström
2010
Computational Intelligence in Engineering
IJ Rudas, J Fodor, J Kacprzyk
2010
Effects of sleep fragmentation on glucose metabolism in normal subjects
KA Stamatakis, NM Punjabi
Chest 2009
A double-blind, placebo-controlled trial of rosiglitazone for clozapine-induced glucose metabolism impairment in patients with Schizophrenia
DC Henderson, X Fan, B Sharma, PM Copeland, CP Borba, R Boxill, O Freudenreich, C Cather, AE Evins, DC Goff
Acta Psychiatrica Scandinavica 2009
Nutritional systems biology modeling: from molecular mechanisms to physiology
AA de Graaf, AP Freidig, BD Roos, N Jamshidi, M Heinemann, JA Rullmann, KD Hall, M Adiels, B Ommen
PLoS computational biology 2009
Successful Versus Failed Adaptation to High-Fat Diet-Induced Insulin Resistance: The Role of IAPP-Induced  -Cell Endoplasmic Reticulum Stress
AV Matveyenko, T Gurlo, M Daval, AE Butler, PC Butler
Diabetes 2009
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
CB Newgard, J An, JR Bain, MJ Muehlbauer, RD Stevens, LF Lien, AM Haqq, SH Shah, M Arlotto, CA Slentz, J Rochon, D Gallup, O Ilkayeva, BR Wenner, WS Yancy, H Eisenson, G Musante, RS Surwit, DS Millington, MD Butler, LP Svetkey
Cell Metabolism 2009
Combined risk allele score of eight type 2 diabetes genes is associated with reduced first-phase glucose-stimulated insulin secretion during hyperglycemic clamps
LM Hart, AM Simonis-Bik, G Nijpels, TW van Haeften, SA Schäfer, JJ Houwing-Duistermaat, DI Boomsma, MJ Groenewoud, E Reiling, EC van Hove, M Diamant, MH Kramer, RJ Heine, JA Maassen, K Kirchhoff, F Machicao, HU Häring, PE Slagboom, G Willemsen, EM Eekhoff, EJ de Geus, JM Dekker, A Fritsche
Diabetes 2009
Genetic Variants of TCF7L2 Are Associated with Insulin Resistance and Related Metabolic Phenotypes in Taiwanese Adolescents and Caucasian Young Adults
PH Liu, YC Chang, YD Jiang, WJ Chen, TJ Chang, SS Kuo, KC Lee, PC Hsiao, KC Chiu, LM Chuang
The Journal of clinical endocrinology and metabolism 2009
An empirical index of insulin sensitivity from short IVGTT: validation against the minimal model and glucose clamp indices in patients with different clinical characteristics
A Tura, S Sbrignadello, E Succurro, L Groop, G Sesti, G Pacini
Diabetologia 2009
Modeling of glucose regulation and insulin-signaling pathways
YH Chew, YL Shia, CT Lee, FA Majid, LS Chua, MR Sarmidi, RA Aziz
Molecular and Cellular Endocrinology 2009
Waist Circumference is the Best Anthropometric Predictor for Insulin Resistance in Nondiabetic Patients with Schizophrenia Treated with Clozapine but not Olanzapine
DC Henderson, X Fan, B Sharma, PM Copeland, CP Borba, O Freudenreich, C Cather, AE Evins, DC Goff
Journal of Psychiatric Practice 2009
β-Cell research - A decade of rapid growth
B Ahrén, D Accili, C Boitard, S Efendic, JC Henquin, S Seino, DF Steiner, E Cerasi
Diabetes, Obesity and Metabolism 2009
Fish oil diets do not improve insulin sensitivity and secretion in healthy adult male pigs
CA Castellano, I Audet, JP Laforest, Y Chouinard, JJ Matte
British Journal of Nutrition 2009
Glucose Metabolism and Diet Predict Changes in Adiposity and Fat Distribution in Weight-reduced Women
BA Gower, GR Hunter, PC Chandler-Laney, JA Alvarez, NC Bush
Obesity 2009
Optimisation of the frequently sampled intravenous glucose tolerance test to reduce urinary glucose spilling in horses
F Tóth, N Frank, SB Elliott, K Perdue, RJ Geor, RC Boston
Equine Veterinary Journal 2009
Diabetes: Models, Signals, and Control
C Cobelli, CD Man, G Sparacino, L Magni, GD Nicolao, BP Kovatchev
IEEE reviews in biomedical engineering 2009
Nonlinear modeling of the dynamic effects of infused insulin on glucose: comparison of compartmental with Volterra models
GD Mitsis, MG Markakis, VZ Marmarelis
IEEE transactions on bio-medical engineering 2009
Fat distribution, aerobic fitness, blood lipids, and insulin sensitivity in African-American and European-American women
GR Hunter, PC Chandler-Laney, DW Brock, C Lara-Castro, JR Fernandez, BA Gower
Obesity (Silver Spring, Md.) 2009
Effects of low- and high-glycemic index/glycemic load diets on coronary heart disease risk factors in overweight/obese men
JM Shikany, RP Phadke, DT Redden, BA Gower
Metabolism: clinical and experimental 2009
Uncoupling protein 2 Ala55Val polymorphism is associated with a higher acute insulin response to glucose
AL Willig, KR Casazza, J Divers, AW Bigham, BA Gower, GR Hunter, JR Fernandez
Metabolism: clinical and experimental 2009
Safety constraints in an artificial pancreatic beta cell: an implementation of model predictive control with insulin on board
C Ellingsen, E Dassau, H Zisser, B Grosman, MW Percival, L Jovanovic, FJ 3rd
Journal of diabetes science and technology 2009
A minimal C-peptide sampling method to capture peak and total prehepatic insulin secretion in model-based experimental insulin sensitivity studies
T Lotz, U Göltenbott, JG Chase, P Docherty, CE Hann
Journal of diabetes science and technology 2009
Single walled carbon nanotubes as reporters for the optical detection of glucose
PW Barone, MS Strano
Journal of diabetes science and technology 2009
Variation in IGF2BP2 Interacts With Adiposity to Alter Insulin Sensitivity in Mexican Americans
X Li, H Allayee, AH Xiang, E Trigo, J Hartiala, JM Lawrence, TA Buchanan, RM Watanabe
Obesity 2009
Validating a Dimensionless Number for Glucose Homeostasis in Humans
DJ Klinke
Annals of Biomedical Engineering 2009
Insulin action and secretion in hypertension in the absence of metabolic syndrome: model-based assessment from oral glucose tolerance test
R Burattini, FD Nardo, F Casagrande, M Boemi, P Morosini
Metabolism 2009
Weighting Restriction for Intravenous Insulin Delivery on T1DM Patient via <formula formulatype="inline"><tex Notation="TeX">$H_{\infty}$</tex> </formula> Control
R Femat, E Ruiz-Velazquez, G Quiroz
IEEE Transactions on Automation Science and Engineering 2009
The impact of family history of type 2 diabetes on pancreatic β-cell function
Z Wang, SH Zhang, L Gong, W Ren, R Li, R Zheng, Y Zhang, M Wang, Q Li
Diabetes Research and Clinical Practice 2009
Effect of input excitation on the quality of empirical dynamic models for type 1 diabetes
DA Finan, CC Palerm, FJ Doyle, DE Seborg, H Zisser, WC Bevier, L Jovanovič
AIChE Journal 2009
Evaluation of proposed oral disposition index measures in relation to the actual disposition index
R Retnakaran, Y Qi, MI Goran, JK Hamilton
Diabetic Medicine 2009
A Novel Blood Glucose Regulation Using TSK<formula formulatype="inline"><tex Notation="TeX">$^{0}$</tex></formula>-FCMAC: A Fuzzy CMAC Based on the Zero-Ordered TSK Fuzzy Inference Scheme
CW Ting, C Quek
IEEE Transactions on Neural Networks 2009
Optimal blood glucose regulation of diabetic patients using single network adaptive critics
SF Ali, R Padhi
Optimal Control Applications and Methods 2009
Effects of low-dose oligofructose treatment administered via nasogastric intubation on induction of laminitis and associated alterations in glucose and insulin dynamics in horses
KA Kalck, N Frank, SB Elliott, RC Boston
American Journal of Veterinary Research 2009
Modulation of Zn-induced hyperinsulinemia/insulin resistance in Wistar rat fed modified poultry eggΨ
SK Taneja, R Mandal
BioFactors 2009
Multi-objective blood glucose control for type 1 diabetes
P Dua, FJ Doyle, EN Pistikopoulos
Medical & Biological Engineering & Computing 2009
Hyperinsulinaemia, a key factor of the metabolic syndrome in postmenopausal women
U Gaspard
Maturitas 2009
Greater omentectomy improves insulin sensitivity in non-obese dogs
M Lottati, CM Kolka, D Stefanovski, EL Kirkman, RN Bergman
Obesity (Silver Spring, Md.) 2009
Insulin sensitivity and glucose dynamics during pre-weaning foal development and in response to maternal diet composition
LA George, WB Staniar, KH Treiber, PA Harris, RJ Geor
Domestic Animal Endocrinology 2009
Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice
JR Fineman, R Clyman
Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice 2009
Weighting Restriction for Intravenous Insulin Delivery on T1DM Patient via $H_{\infty}$ Control
R Femat, E Ruiz-Velazquez, G Quiroz
IEEE Transactions on Automation Science and Engineering 2009
The Minimal Model of Glucose Disposal in the Analysis of Glucose Effectiveness: Importance of Early Insulin Data
JL Gooley, JM Walters, GM Ward
Diabetes Technology & Therapeutics 2009
A Novel Blood Glucose Regulation Using TSK$^{0}$-FCMAC: A Fuzzy CMAC Based on the Zero-Ordered TSK Fuzzy Inference Scheme
CW Ting, C Quek
IEEE Transactions on Neural Networks 2009
Modulation of Zn-induced hyperinsulinemia/insulin resistance in Wistar rat fed modified poultry egg Ψ
SK Taneja, R Mandal
BioFactors 2009
A molecular mathematical model of glucose mobilization and uptake
W Liu, CC Hsin, F Tang
Mathematical Biosciences 2009
Regulation of Insulin Action by Diet and Exercise
SL Schmidt, MS Hickey
Journal of Equine Veterinary Science 2009
Yen & Jaffe's Reproductive Endocrinology
SF Thung, ER Norwitz
Yen & Jaffe's Reproductive Endocrinology 2009
Overweight is associated with impaired  -cell function during pregnancy: a longitudinal study of 553 normal pregnancies
E Qvigstad, N Voldner, K Godang, T Henriksen, J Bollerslev
European Journal of Endocrinology 2009
Low plasma insulin-like growth factor-1 levels are associated with reduced insulin sensitivity and increased insulin secretion in nondiabetic subjects
E Succurro, F Andreozzi, MA Marini, R Lauro, ML Hribal, F Perticone, G Sesti
Nutrition, Metabolism and Cardiovascular Diseases 2009
Gene Variants in the Novel Type 2 Diabetes Loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B Affect Different Aspects of Pancreatic  -Cell Function
AM Simonis-Bik, G Nijpels, TW van Haeften, JJ Houwing-Duistermaat, DI Boomsma, E Reiling, EC van Hove, M Diamant, MH Kramer, RJ Heine, JA Maassen, PE Slagboom, G Willemsen, JM Dekker, EM Eekhoff, EJ de Geus, LM Hart
Diabetes 2009
Structural Identifiability of the Minimal Model and a Euglycemic Hyperinsulinemic Clamp Model for glucose-insulin dynamics
SV Chin, MJ Chappell
IFAC Proceedings Volumes 2009
Comparative study of different control techniques for the regulation of blood glucose level in diabetic patients
MS Ibbini
Journal of Medical Engineering & Technology 2009
Prediction Performance Comparison between three Intensive Care Unit Glucose Models
T Herpe, N Haverbeke, G Berghe, BD Moor
IFAC Proceedings Volumes 2009
Induced L2-norm Minimization of Glucose-Insulin System for Type I Diabetic Patients
L Kovács, B Kulcsár, B Benyó, Z Benyó
IFAC Proceedings Volumes 2009
A Review of Closed-Loop Algorithms for Glycemic Control in the Treatment of Type 1 Diabetes
JE Youssef, J Castle, WK Ward
Algorithms 2009
Model based validation of meal inputs in diabetes therapy
GC Estrada, H Kirchsteiger, L Re, E Renard
IFAC Proceedings Volumes 2009
Nutritional Systems Biology Modeling: From Molecular Mechanisms to Physiology
AA de Graaf, AP Freidig, BD Roos, N Jamshidi, M Heinemann, JA Rullmann, KD Hall, M Adiels, B Ommen, PE Bourne
PLoS computational biology 2009
Effects of prolonged fasting and sustained lipolysis on insulin secretion and insulin sensitivity in normal subjects
B Salgin, ML Marcovecchio, SM Humphreys, N Hill, LJ Chassin, DJ Lunn, R Hovorka, DB Dunger
American journal of physiology. Endocrinology and metabolism 2009
Evaluation of different methods for assessment of insulin sensitivity in Göttingen minipigs: introduction of a new, simpler method
B Christoffersen, U Ribel, K Raun, V Golozoubova, G Pacini
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2009
Safety Constraints in an Artificial Pancreatic β Cell: An Implementation of Model Predictive Control with Insulin on Board
C Ellingsen, E Dassau, H Zisser, B Grosman, MW Percival, L Jovanovič, FJ Doyle
Journal of diabetes science and technology 2009
2nd International Workshop on Practical Applications of Computational Biology and Bioinformatics (IWPACBB 2008)
JM Corchado, JF Paz, MP Rocha, FF Riverola
2009
Springer Handbook of Automation
SY Nof
2009
Optimal Design of Clinical Tests for the Identification of Physiological Models of Type 1 Diabetes Mellitus
F Galvanin, M Barolo, S Macchietto, F Bezzo
Industrial & engineering chemistry research 2009
Fat Mass Accumulation during Childhood Determines Insulin Sensitivity in Early Adulthood
RW Leunissen, P Oosterbeek, LK Hol, AA Hellingman, T Stijnen, AC Hokken-Koelega
The Journal of clinical endocrinology and metabolism 2008
Targeting β-Cell Mass in Type 2 Diabetes: Promise and Limitations of New Drugs Based on Incretins
M Salehi, BA Aulinger, DA D'Alessio
Endocrine reviews 2008
Evidence that autonomic mechanisms contribute to the adaptive increase in insulin secretion during dexamethasone-induced insulin resistance in humans
B Ahrén
Diabetologia 2008
Ethnicity and Weight Status Affect the Accuracy of Proxy Indices of Insulin Sensitivity
JA Alvarez, NC Bush, GR Hunter, DW Brock, BA Gower
Obesity 2008
Short-Term Exercise Improves β-Cell Function and Insulin Resistance in Older People with Impaired Glucose Tolerance
CJ Bloem, AM Chang
The Journal of clinical endocrinology and metabolism 2008
The future of open- and closed-loop insulin delivery systems
TG Farmer, TF Edgar, NA Peppas
Journal of Pharmacy and Pharmacology 2008
An extension to the compartmental model of type 1 diabetic patients to reproduce exercise periods with glycogen depletion and replenishment
M Hernández-Ordoñez, DU Campos-Delgado
Journal of Biomechanics 2008
Simulation models for in silico testing of closed-loop glucose controllers in type 1 diabetes
ME Wilinska, R Hovorka
Drug Discovery Today: Disease Models 2008
Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and beta-cell mass to age-related insulin resistance in rats
AV Matveyenko, JD Veldhuis, PC Butler
American journal of physiology. Endocrinology and metabolism 2008
Insulin Secretion in Metabolically Obese, but Normal Weight, and in Metabolically Healthy but Obese Individuals
E Succurro, MA Marini, S Frontoni, ML Hribal, F Andreozzi, R Lauro, F Perticone, G Sesti
Obesity 2008
Combined association of maternal and paternal family history of diabetes with plasma leptin and adiponectin in overweight Hispanic children
C Koebnick, LA Kelly, CJ Lane, CK Roberts, GQ Shaibi, CM Toledo-Corral, JN Davis, MJ Weigensberg, MI Goran
Diabetic medicine : a journal of the British Diabetic Association 2008
Insulin sensitivity in African-American and white women: association with inflammation
TC Hyatt, RP Phadke, GR Hunter, NC Bush, AJ Muñoz, BA Gower
Obesity (Silver Spring, Md.) 2008
Insulin-stimulated release of D-chiro-inositol-containing inositolphosphoglycan mediator correlates with insulin sensitivity in women with polycystic ovary syndrome
KI Cheang, JP Baillargeon, PA Essah, RE Ostlund, T Apridonize, L Islam, JE Nestler
Metabolism: clinical and experimental 2008
Functional impact of high protein intake on healthy elderly people
S Walrand, KR Short, ML Bigelow, AJ Sweatt, SM Hutson, KS Nair
American journal of physiology. Endocrinology and metabolism 2008
Mathematical models of energy homeostasis
R Pattaranit, HA van Berg
Journal of the Royal Society, Interface / the Royal Society 2008
A Survey of Insulin-Dependent Diabetes-Part II: Control Methods
D Takahashi, Y Xiao, F Hu
International journal of telemedicine and applications 2008
Greek hyperinsulinemic women, with or without polycystic ovary syndrome, display altered inositols metabolism
JP Baillargeon, JE Nestler, RE Ostlund, T Apridonidze, E Diamanti-Kandarakis
Human reproduction (Oxford, England) 2008
Evidence for pancreatic beta-cell dysfunction in brothers of women with polycystic ovary syndrome
S Sam, YA Sung, RS Legro, A Dunaif
Metabolism: clinical and experimental 2008
Closed-loop control and advisory mode evaluation of an artificial pancreatic Beta cell: use of proportional-integral-derivative equivalent model-based controllers
MW Percival, H Zisser, L Jovanovic, FJ 3rd
Journal of diabetes science and technology 2008
Baseline inflammatory markers do not modulate the lipid response to weight loss
MP St-Onge, R Desmond, G Hunter, B Gower
Metabolism 2008
Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes
JA Jacobsson, P Danielsson, V Svensson, J Klovins, U Gyllensten, C Marcus, HB Schiöth, R Fredriksson
Biochemical and Biophysical Research Communications 2008
Global meta-analysis of the C-11377G alteration in the ADIPOQ gene indicates the presence of population-specific effects: challenge for global health initiatives
PE Schwarz, GW Towers, A der Merwe, L Perez-Perez, P Rheeder, J Schulze, SR Bornstein, J Licinio, ML Wong, AE Schutte, A Olckers
The Pharmacogenomics Journal 2008
Effects of an intravenous endotoxin challenge on glucose and insulin dynamics in horses
F Tóth, N Frank, SB Elliott, RJ Geor, RC Boston
American Journal of Veterinary Research 2008
Glucagon-like peptide-1 in type 2 diabetes: the -cell and beyond
MA Nauck
Diabetes, Obesity and Metabolism 2008
Hyperbolic Relationship Between Insulin Secretion and Sensitivity on Oral Glucose Tolerance Test
R Retnakaran, S Shen, AJ Hanley, V Vuksan, JK Hamilton, B Zinman
Obesity 2008
Modeling a simplified regulatory system of blood glucose at molecular levels
W Liu, F Tang
Journal of Theoretical Biology 2008
Effects of long-term oral administration of levothyroxine sodium on glucose dynamics in healthy adult horses
N Frank, SB Elliott, RC Boston
American Journal of Veterinary Research 2008
Plasma and dietary vitamin E in relation to insulin secretion and sensitivity
T Costacou, B Ma, IB King, EJ Mayer-Davis
Diabetes, Obesity and Metabolism 2008
Simulation and initial proof-of-concept validation of a glycaemic regulation algorithm in critical care
JG Chase, XW Wong, I Singh-Levett, LJ Hollingsworth, CE Hann, GM Shaw, T Lotz, J Lin
Control Engineering Practice 2008
Adverse effects of obesity on β-cell function in Japanese subjects with normal glucose tolerance
Y Akehi, K Anzai, H Katsuta, R Yoshida, K Ohkubo, T Yamashita, H Kawashima, J Ono
Obesity Research & Clinical Practice 2008
MPC on a chip—Recent advances on the application of multi-parametric model-based control
P Dua, K Kouramas, V Dua, EN Pistikopoulos
Computers & chemical engineering 2008
 - and  -Cell Dysfunction in Subjects Developing Impaired Glucose Tolerance: Outcome of a 12-Year Prospective Study in Postmenopausal Caucasian Women
B Ahren
Diabetes 2008
 -Cell Dysfunction in Subjects With Impaired Glucose Tolerance and Early Type 2 Diabetes: Comparison of Surrogate Markers With First-Phase Insulin Secretion From an Intravenous Glucose Tolerance Test
A Festa, K Williams, AJ Hanley, SM Haffner
Diabetes 2008
Persistence of Pre-Diabetes in Overweight and Obese Hispanic Children: Association With Progressive Insulin Resistance, Poor  -Cell Function, and Increasing Visceral Fat
MI Goran, C Lane, C Toledo-Corral, MJ Weigensberg
Diabetes 2008
Oral Disposition Index Predicts the Development of Future Diabetes Above and Beyond Fasting and 2-h Glucose Levels
KM Utzschneider, RL Prigeon, MV Faulenbach, J Tong, DB Carr, EJ Boyko, DL Leonetti, MJ McNeely, WY Fujimoto, SE Kahn
Diabetes care 2008
Encyclopedia of Biomaterials and Biomedical Engineering, Second Edition - Four Volume Set
B Walpoth, O Hess
Encyclopedia of Biomaterials and Biomedical Engineering, Second Edition - Four Volume Set 2008
Long-term repeatability of measures of early insulin secretion derived from an intravenous glucose tolerance test and conversion from impaired glucose tolerance to diabetes
DE Laaksonen, L Niskanen, H Mykkänen, KS Juntunen, U Schwab, M Kolehmainen, R Rauramaa, J Tuomilehto, M Uusitupa
Annals of Medicine 2008
Nonlinear model predictive control with moving horizon state and disturbance estimation - Application to the normalization of blood glucose in the critically ill
N Haverbeke, TV Herpe, M Diehl, GV Berghe, BD Moor
IFAC Proceedings Volumes 2008
Event-based Feedforward Control of a Drug Delivery System for Diabetes Care
R Yang, TJ Tarn, M Zhang
IFAC Proceedings Volumes 2008
Adaptation to intermittent stress promotes maintenance of β-cell compensation: comparison with food restriction
HE Bates, A Sirek, MA Kiraly, JT Yue, MC Riddell, SG Matthews, M Vranic
American journal of physiology. Endocrinology and metabolism 2008
Functional impact of high protein intake on healthy elderly people
S Walrand, KR Short, ML Bigelow, AJ Sweatt, SM Hutson, KS Nair
American journal of physiology. Endocrinology and metabolism 2008
Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and β-cell mass to age-related insulin resistance in rats
AV Matveyenko, JD Veldhuis, PC Butler
American journal of physiology. Endocrinology and metabolism 2008
Closed-Loop Control and Advisory Mode Evaluation of an Artificial Pancreatic β Cell: Use of Proportional-Integral-Derivative Equivalent Model-Based Controllers
MW Percival, H Zisser, L Jovanovic, FJ Doyle
Journal of diabetes science and technology 2008
PPARα activation and increased dietary lipid oppose thyroid hormone signaling and rescue impaired glucose-stimulated insulin secretion in hyperthyroidism
MJ Holness, GK Greenwood, ND Smith, MC Sugden
American journal of physiology. Endocrinology and metabolism 2008
Type 2 Diabetes Mellitus
MN Feinglos, MA Bethel
2008
4th Kuala Lumpur International Conference on Biomedical Engineering 2008
NA Osman, F Ibrahim, WA Abas, HS Rahman, HN Ting
2008
Hormonal regulation of glucose clearance in lactating northern elephant seals ( Mirounga angustirostris )
MA Fowler, CD Champagne, DS Houser, DE Crocker
The Journal of experimental biology 2008
Pharmacokinetic/Pharmacodynamic Modelling in??Diabetes Mellitus:
CB Landersdorfer, WJ Jusko
Clinical Pharmacokinetics 2008
Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes
Valeriya Lyssenko, Roberto Lupi, Piero Marchetti, Silvia Del Guerra, Marju Orho-Melander, Peter Almgren, Marketa Sjögren, Charlotte Ling, Karl-Fredrik Eriksson, Åsa-Linda Lethagen, Rita Mancarella, Göran Berglund, Tiinamaija Tuomi, Peter Nilsson, Stefano Del Prato, and Leif Groop
Journal of Clinical Investigation 2007
Oral taurine but not N-acetylcysteine ameliorates NEFA-induced impairment in insulin sensitivity and beta cell function in obese and overweight, non-diabetic men
C Xiao, A Giacca, GF Lewis
Diabetologia 2007
Orchestration of Glucose Homeostasis: From a Small Acorn to the California Oak
RN Bergman
Diabetes 2007
Evidence for a Role of Superoxide Generation in Glucose-Induced  -Cell Dysfunction In Vivo
C Tang, P Han, AI Oprescu, SC Lee, AV Gyulkhandanyan, GN Chan, MB Wheeler, A Giacca
Diabetes 2007
Glucagon receptor antagonism improves islet function in mice with insulin resistance induced by a high-fat diet
MS Winzell, CL Brand, N Wierup, UG Sidelmann, F Sundler, E Nishimura, B Ahrén
Diabetologia 2007
Polymorphisms in the gene encoding the voltage-dependent Ca2+ channel CaV2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion
J Holmkvist, D Tojjar, P Almgren, V Lyssenko, CM Lindgren, B Isomaa, T Tuomi, G Berglund, E Renström, L Groop
Diabetologia 2007
Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study
M Laakso, J Zilinskaite, T Hansen, TW Boesgaard, M Vänttinen, A Stančáková, PA Jansson, F Pellmé, JJ Holst, T Kuulasmaa, ML Hribal, G Sesti, N Stefan, A Fritsche, H Häring, O Pedersen, U Smith
Diabetologia 2007
Polycystic Ovary Syndrome
MA Brown, RJ Chang
Ultrasound Quarterly 2007
Adiposity and Insulin Sensitivity Derived from Intravenous Glucose Tolerance Tests in Antipsychotic-Treated Patients
DW Haupt, PA Fahnestock, KA Flavin, JA Schweiger, A Stevens, MJ Hessler, J Maeda, M Yingling, JW Newcomer
Neuropsychopharmacology 2007
Genetics of gestational diabetes mellitus and type 2 diabetes
RM Watanabe, MH Black, AH Xiang, H Allayee, JM Lawrence, TA Buchanan
Diabetes care 2007
Effect of pioglitazone on progression of subclinical atherosclerosis in non-diabetic premenopausal Hispanic women with prior gestational diabetes
AH Xiang, HN Hodis, M Kawakubo, RK Peters, SL Kjos, A Marroquin, J Goico, C Ochoa, CR Liu, CH Liu, TA Buchanan
Atherosclerosis 2007
Transcription factor 7-like 2 (TCF7L2) is associated with gestational diabetes mellitus and interacts with adiposity to alter insulin secretion in Mexican Americans
RM Watanabe, H Allayee, AH Xiang, E Trigo, J Hartiala, JM Lawrence, TA Buchanan
Diabetes 2007
Lower bone mineral content in hypertensive compared with normotensive overweight Latino children and adolescents
A Afghani, MI Goran
American Journal of Hypertension 2007
Dynamic modeling of exercise effects on plasma glucose and insulin levels
A Roy, RS Parker
Journal of diabetes science and technology 2007
Analysis of algorithms for intensive care unit blood glucose control
BW Bequette
Journal of diabetes science and technology 2007
Glycemia prediction in critically ill patients using an adaptive modeling approach
TV Herpe, M Espinoza, N Haverbeke, BD Moor, GV Berghe
Journal of diabetes science and technology 2007
Comparisons of glucose–insulin homeostasis following maprotiline and fluoxetine treatment in depressed males
YC Chen, YC Shen, YJ Hung, C Chao-Ha, CB Yeh, CH Perng
Journal of Affective Disorders 2007
Insulin sensitivity, proinflammatory markers and adiponectin in young males with different subtypes of depressive disorder
YJ Hung, CH Hsieh, YJ Chen, D Pei, SW Kuo, DC Shen, WH Sheu, YC Chen
Clinical Endocrinology 2007
Protective effect against type 2 diabetes mellitus identified within the ACDC gene in a black South African diabetic cohort
A Olckers, GW Towers, A der Merwe, PE Schwarz, P Rheeder, AE Schutte
Metabolism 2007
Elements of the Metabolic Syndrome: Association with Insulin Sensitivity and Effects of Ethnicity
BA Gower, JD Ard, GR Hunter, J Fernandez, F Ovalle
Metabolic Syndrome and Related Disorders 2007
TYPE 1 DIABETIC PATIENT INSULIN DELIVERY USING ASYMMETRIC PI CONTROL
JA Gantt, KA Rochelle, EP Gatzke
Chemical Engineering Communications 2007
Obstetrics: Normal and Problem Pregnancies
MC Gordon
Obstetrics: Normal and Problem Pregnancies 2007
Clinical Validation of a New Control-Oriented Model of Insulin and Glucose Dynamics in Subjects with Type 1 Diabetes
PG Fabietti, V Canonico, M Orsini-Federici, E Sarti, M Massi-Benedetti
Diabetes Technology & Therapeutics 2007
On hyperglicemic glucose basal levels in Type 1 Diabetes Mellitus from dynamic analysis
G Quiroz, R Femat
Mathematical Biosciences 2007
Modelling the effect of CSII on the control of glucose concentration in type 1 diabetes
Nilam, Murray E. Alexander, Ruchi Mathur, Seyed M. Moghadas, Pappur N. Shivakumar
Applied Mathematics and Computation 2007
Effects of Nonglucose Nutrients on Insulin Secretion and Action in People With Pre-Diabetes
G Bock, CD Man, M Campioni, E Chittilapilly, R Basu, G Toffolo, C Cobelli, R Rizza
Diabetes 2007
Evidence of Interaction Between PPARG2 and HNF4A Contributing to Variation in Insulin Sensitivity in Mexican Americans
MH Black, TE Fingerlin, H Allayee, W Zhang, AH Xiang, E Trigo, J Hartiala, AB Lehtinen, SM Haffner, RN Bergman, RC McEachin, SL Kjos, JM Lawrence, TA Buchanan, RM Watanabe
Diabetes 2007
Two Years of Treatment With Dehydroepiandrosterone Does Not Improve Insulin Secretion, Insulin Action, or Postprandial Glucose Turnover in Elderly Men or Women
R Basu, CD Man, M Campioni, A Basu, KS Nair, MD Jensen, S Khosla, G Klee, G Toffolo, C Cobelli, RA Rizza
Diabetes 2007
Comprehensive Medicinal Chemistry II
E Littler, XX Zhou
Comprehensive Medicinal Chemistry II 2007
ADAPTIVE MODELING FOR CONTROL OF GLYCEMIA IN CRITICALLY ILL PATIENTS
TV Herpe, N Haverbeke, M Espinoza, GV Berghe, BD Moor
IFAC Proceedings Volumes 2007
Lipid-induced β-cell dysfunction in vivo in models of progressive β-cell failure
TT Goh, TM Mason, N Gupta, A So, TK Lam, L Lam, GF Lewis, A Mari, A Giacca
American journal of physiology. Endocrinology and metabolism 2007
Assessment of β-cell function in humans, simultaneously with insulin sensitivity and hepatic extraction, from intravenous and oral glucose tests
C Cobelli, GM Toffolo, CD Man, M Campioni, P Denti, A Caumo, P Butler, R Rizza
American journal of physiology. Endocrinology and metabolism 2007
Algebraic Biology
H Anai, K Horimoto, T Kutsia
2007
Insulin Resistance and Polycystic Ovarian Syndrome
E Diamanti-Kandarakis, JE Nestler, D Panidis, R Pasquali
2007
SUIT, secretory units of islets in transplantation: An index for therapeutic management of islet transplanted patients and its application to type 2 diabetes
Y Yamada, K Fukuda, S Fujimoto, M Hosokawa, K Tsukiyama, K Nagashima, M Fukushima, H Suzuki, K Toyoda, M Sassa, S Funakoshi, N Inagaki, A Taniguchi, TS Sato, S Matsumoto, K Tanaka, Y Seino
Diabetes Research and Clinical Practice 2006
Glucagon Receptor Knockout Mice Display Increased Insulin Sensitivity and Impaired  -Cell Function
H Sorensen, MS Winzell, CL Brand, K Fosgerau, RW Gelling, E Nishimura, B Ahren
Diabetes 2006
Encyclopedia of Medical Devices and Instrumentation
HT Whelan, JA Niezgoda, MC Lewis, EP Kindwall, B Cabigas
Encyclopedia of Medical Devices and Instrumentation 2006
Differential effects of monounsaturated, polyunsaturated and saturated fat ingestion on glucose-stimulated insulin secretion, sensitivity and clearance in overweight and obese, non-diabetic humans
C Xiao, A Giacca, A Carpentier, GF Lewis
Diabetologia 2006
Changes in Intra-abdominal Fat in Early Postmenopausal Women: Effects of Hormone Use*
BA Gower, J Muñoz, R Desmond, T Hilario-Hailey, X Jiao
Obesity 2006
Cutoff values of surrogate measures of insulin resistance for metabolic syndrome in Korean non-diabetic adults
S Lee, S Choi, HJ Kim, YS Chung, KW Lee, HC Lee, KB Huh, DJ Kim
Journal of Korean Medical Science 2006
Deterioration of insulin sensitivity and beta-cell function in overweight Hispanic children during pubertal transition: a longitudinal assessment
MI Goran, GQ Shaibi, MJ Weigensberg, JN Davis, ML Cruz
International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity 2006
Role of diet in the treatment of polycystic ovary syndrome
CC Douglas, BA Gower, BE Darnell, F Ovalle, RA Oster, R Azziz
Fertility and Sterility 2006
The hyperbolic equilibrium between insulin sensitivity and secretion
G Pacini
Nutrition, Metabolism and Cardiovascular Diseases 2006
Assessing progression to impaired glucose tolerance and type�2 diabetes mellitus
F Guerrero-Romero, M Rodríguez-Morán
European Journal of Clinical Investigation 2006
Run-to-Run Control of Blood Glucose Concentrations for People With Type 1 Diabetes Mellitus
C Owens, H Zisser, L Jovanovic, B Srinivasan, D Bonvin, FJ Doyle
IEEE Transactions on Biomedical Engineering 2006
Automated insulin delivery for type 1 diabetes
GM Steil, MF Saad
Current Opinion in Endocrinology & Diabetes 2006
Control oriented model of insulin and glucose dynamics in type 1 diabetics
PG Fabietti, V Canonico, MO Federici, MM Benedetti, E Sarti
Medical & Biological Engineering & Computing 2006
Effects of pioglitazone on beta-cell function in metabolic syndrome patients with impaired glucose tolerance
J Jin, Y Yu, H Yu, C Wang, X Zhang
Diabetes Research and Clinical Practice 2006
Virtual type 1 diabetic patient for feedback control systems
V Canonico, PG Fabietti, MM Benedetti, MO Federici, E Sarti
Diabetes Research and Clinical Practice 2006
Dynamic Modeling of Free Fatty Acid, Glucose, and Insulin: An Extended "Minimal Model"
A Roy, RS Parker
Diabetes Technology & Therapeutics 2006
Automated insulin delivery for type 1 diabetes:
GM Steil, MF Saad
Current Opinion in Endocrinology & Diabetes 2006
Metabolic consequences of prematurity
WS Cutfield, PL Hofman, MA Sperling
Expert Review of Endocrinology & Metabolism 2006
Model predictive glycaemic regulation in critical illness using insulin and nutrition input: A pilot study
XW Wong, JG Chase, GM Shaw, CE Hann, T Lotz, J Lin, I Singh-Levett, LJ Hollingsworth, OS Wong, S Andreassen
Medical engineering & physics 2006
Aging is an Inevitable Risk Factor for Insulin Resistance
MR Refaie, NA Sayed-Ahmed, AM Bakr, MY Aziz, MH el Kannishi, SS Abdel-Gawad
Journal of Taibah University Medical Sciences 2006
Effects of Age and Sex on Postprandial Glucose Metabolism: Differences in Glucose Turnover, Insulin Secretion, Insulin Action, and Hepatic Insulin Extraction
R Basu, CD Man, M Campioni, A Basu, G Klee, G Toffolo, C Cobelli, RA Rizza
Diabetes 2006
Polymorphism in the Transcription Factor 7-Like 2 (TCF7L2) Gene Is Associated With Reduced Insulin Secretion in Nondiabetic Women
J Munoz, KH Lok, BA Gower, JR Fernandez, GR Hunter, C Lara-Castro, MD Luca, WT Garvey
Diabetes 2006
New Insights on the Simultaneous Assessment of Insulin Sensitivity and  -Cell Function With the HOMA2 Method
A Caumo, G Perseghin, A Brunani, L Luzi
Diabetes care 2006
Pathogenesis of Pre-Diabetes: Mechanisms of Fasting and Postprandial Hyperglycemia in People With Impaired Fasting Glucose and/or Impaired Glucose Tolerance
G Bock, CD Man, M Campioni, E Chittilapilly, R Basu, G Toffolo, C Cobelli, R Rizza
Diabetes 2006
The Natural Course of  -Cell Function in Nondiabetic and Diabetic Individuals: The Insulin Resistance Atherosclerosis Study
A Festa, K Williams, R D'Agostino, LE Wagenknecht, SM Haffner
Diabetes 2006
Effect of Pioglitazone on Pancreatic  -Cell Function and Diabetes Risk in Hispanic Women With Prior Gestational Diabetes
AH Xiang, RK Peters, SL Kjos, A Marroquin, J Goico, C Ochoa, M Kawakubo, TA Buchanan
Diabetes 2006
A PI-fuzzy logic controller for the regulation of blood glucose level in diabetic patients
M Ibbini
Journal of Medical Engineering & Technology 2006
DYNAMIC MODELING OF EXERCISE EFFECTS ON PLASMA GLUCOSE AND INSULIN LEVELS
A Roy, RS Parker
IFAC Proceedings Volumes 2006
MODELLING LIGHT AND MODERATE EXERCISE IN TYPE 1 DIABETIC PATIENTS WITH GLYCOGEN DEPLETION AND REPLENISHMENT
M Hernández-Ordoñez, DU Campos-Delgado
IFAC Proceedings Volumes 2006
IDENTIFICATION OF LINEAR DYNAMIC MODELS FOR TYPE 1 DIABETES: A SIMULATION STUDY
DA Finan, H Zisser, L Jovanovic, WC Bevier, DE Seborg
IFAC Proceedings Volumes 2006
DEVELOPMENT OF A CRITICALLY ILL PATIENT INPUT-OUTPUT MODEL
TV Herpe, M Espinoza, B Pluymers, P Wouters, FD Smet, GV Berghe, BD Moor
IFAC Proceedings Volumes 2006
Dietary fatty acids and insulin secretion
G Mingrone
Scandinavian Journal of Food & Nutrition 2006
Limitation of the Homeostasis Model Assessment to Predict Insulin Resistance and β-Cell Dysfunction in Older People
AM Chang, MJ Smith, CJ Bloem, AT Galecki, JB Halter, MA Supiano
The Journal of clinical endocrinology and metabolism 2006
Impaired β-Cell Function in Human Aging: Response to Nicotinic Acid-Induced Insulin Resistance
AM Chang, MJ Smith, AT Galecki, CJ Bloem, JB Halter
The Journal of clinical endocrinology and metabolism 2006
Dietary-fat-induced obesity in mice results in beta cell hyperplasia but not increased insulin release: evidence for specificity of impaired beta cell adaptation
RL Hull, K Kodama, KM Utzschneider, DB Carr, RL Prigeon, SE Kahn
Diabetologia 2005
Islet adaptation to insulin resistance: mechanisms and implications for intervention
B Ahren, G Pacini
Diabetes, Obesity and Metabolism 2005
Minimal Model: Perspective from 2005
RN Bergman
Hormone Research 2005
Glucagon secretion in relation to insulin sensitivity in healthy subjects
B Ahrén
Diabetologia 2005
Heritability of model-derived parameters of beta cell secretion during intravenous and oral glucose tolerance tests: a study of twins
M Lehtovirta, J Kaprio, L Groop, M Trombetta, RC Bonadonna
Diabetologia 2005
Reduced insulin sensitivity and the presence of cardiovascular risk factors in short prepubertal children born small for gestational age (SGA)
NJ Arends, VH Boonstra, HJ Duivenvoorden, PL Hofman, WS Cutfield, AC Hokken-Koelega
Clinical Endocrinology 2005
Hyperthyroidism impairs pancreatic beta cell adaptations to late pregnancy and maternal liporegulation in the rat
MJ Holness, GK Greenwood, ND Smith, MC Sugden
Diabetologia 2005
Adiponectin and beta cell dysfunction in gestational diabetes: pathophysiological implications
R Retnakaran, AJ Hanley, N Raif, CR Hirning, PW Connelly, M Sermer, SE Kahn, B Zinman
Diabetologia 2005
Assessment of insulin secretion in relation to insulin resistance
A Mari, B Ahrén, G Pacini
Current Opinion in Clinical Nutrition and Metabolic Care 2005
Use of proxies and reference quintiles obtained from minimal model analysis for determination of insulin sensitivity and pancreatic beta-cell responsiveness in horses
KH Treiber, DS Kronfeld, TM Hess, RC Boston, PA Harris
American Journal of Veterinary Research 2005
Glucose control design using nonlinearity assessment techniques
N Hernjak, FJ Doyle
AIChE Journal 2005
Rosiglitazone improves insulin sensitivity and glucose tolerance in subjects with impaired glucose tolerance
YJ Hung, CH Hsieh, D Pei, SW Kuo, JT Lee, LY Wu, CT He, CH Lee, SC Fan, WH Sheu
Clinical Endocrinology 2005
High normal 2-hour plasma glucose is associated with insulin sensitivity and secretion that may predispose to type 2 diabetes
ME Pich�, S Lemieux, L P�russe, SJ Weisnagel
Diabetologia 2005
Effects of oral administration of levothyroxine sodium on concentrations of plasma lipids, concentration and composition of very-low-density lipoproteins, and glucose dynamics in healthy adult mares
N Frank, CS Sommardahl, H Eiler, LL Webb, JW Denhart, RC Boston
American Journal of Veterinary Research 2005
A population-based Bayesian approach to the minimal model of glucose and insulin homeostasis
KE Andersen, M Højbjerre
Statistics in Medicine 2005
Optimal<tex>$H^infty$</tex>Insulin Injection Control for Blood Glucose Regulation in Diabetic Patients
F Chee, AV Savkin, TL Fernando, S Nahavandi
IEEE Transactions on Biomedical Engineering 2005
Closed-loop insulin delivery – what lies between where we are and where we are going?
GM Steil, K Rebrin
Expert Opinion on Drug Delivery 2005
Insulin resistance: A metabolic pathway to chronic liver disease
E Bugianesi, AJ McCullough, G Marchesini
Hepatology 2005
Atypical antipsychotic drugs, diabetes and ethnicity
J Ananth, S Kolli, S Gunatilake, S Brown
Expert Opinion on Drug Safety 2005
Soluble E-selectin, leptin, triglycerides, and insulin resistance in nonobese Japanese type 2 diabetic patients
A Taniguchi, M Fukushima, Y Nakai, A Kuroe, G Yamano, T Yanagawa, M Ohgushi, M Ohya, S Yoshii, Y Taki, Y Seino
Metabolism 2005
Young, low-birth-weight men are not more susceptible to the diabetogenic effects of a prolonged free fatty acid exposure than matched controls
CB Jensen, H Storgaard, JJ Holst, F Dela, S Madsbad, A Vaag
Metabolism 2005
Prevalence and Determinants of Impaired Glucose Metabolism in Frail Elderly Patients: The Belgian Elderly Diabetes Survey (BEDS)
MP Hermans, TM Pepersack, LH Godeaux, I Beyer, AP Turc
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2005
Sleep Apnea and Metabolic Dysfunction
NM Punjabi, BA Beamer
Principles and Practice of Sleep Medicine 2005
Derivative weighted active insulin control algorithms and intensive care unit trials
CV Doran, JG Chase, GM Shaw, KT Moorhead, NH Hudson
Control Engineering Practice 2005
Pathogenesis of Type 2 Diabetes Mellitus
JL Leahy
Archives of Medical Research 2005
Assessment of insulin secretion in relation to insulin resistance:
A Mari, B Ahrén, G Pacini
Current Opinion in Clinical Nutrition and Metabolic Care 2005
Run-to-Run Control of Meal-Related Insulin Dosing
H Zisser, L Jovanovic, F Doyle, P Ospina, C Owens
Diabetes Technology & Therapeutics 2005
AKA-Glucose: A Program for Kinetic and Epidemiological Analysis of Frequently Sampled Intravenous Glucose Tolerance Test Data Using Database Technology
RC Boston, PJ Moate, D Stefanovski, AE Sumner, RN Bergman
Diabetes Technology & Therapeutics 2005
Principles and Practice of Sleep Medicine
NM Punjabi, BA Beamer
Principles and Practice of Sleep Medicine 2005
Optimal$H^infty$Insulin Injection Control for Blood Glucose Regulation in Diabetic Patients
F Chee, AV Savkin, TL Fernando, S Nahavandi
IEEE Transactions on Biomedical Engineering 2005
Modelling and control of drug delivery systems
P Dua, EN Pistikopoulos
Computers & chemical engineering 2005
The Classification of Diabetes Mellitus: A Conceptual Framework
D Ize-Ludlow, MA Sperling
Pediatric Clinics of North America 2005
The Study of the Effects of Diet on Metabolism and Nutrition (STEDMAN) weight loss project: Rationale and design
AM Haqq, LF Lien, J Boan, M Arlotto, CA Slentz, MJ Muehlbauer, J Rochon, D Gallup, RL McMahon, JR Bain, R Stevens, D Millington, MD Butler, CB Newgard, LP Svetkey
Contemporary clinical trials 2005
Minimal Model Analysis in Nondiabetic Renal Transplant Recipients With Hepatitis C
R López, MA Gentil, D Acosta, MJ Escobar, F Sánchez, P Pereira, GR Algarra, R Astorga
Transplantation Proceedings 2005
A fuzzy logic based closed-loop control system for blood glucose level regulation in diabetics
MS Ibbini, MA Masadeh
Journal of Medical Engineering & Technology 2005
Insulin sensitivity by oral glucose minimal models: validation against clamp
CD Man, KE Yarasheski, A Caumo, H Robertson, G Toffolo, KS Polonsky, C Cobelli
American journal of physiology. Endocrinology and metabolism 2005
Dietary carbohydrate modification enhances insulin secretion in persons with the metabolic syndrome
DE Laaksonen, LK Toppinen, KS Juntunen, K Autio, KH Liukkonen, KS Poutanen, L Niskanen, HM Mykkänen
The American journal of clinical nutrition 2005
The hyperbolic law?a 25-year perspective
M Stumvoll, PA Tataranni, C Bogardus
Diabetologia 2005
To the Editor
TD Hockaday
Diabetologia 2005
Assessment of Insulin Sensitivity from Measurements in the Fasting State and during an Oral Glucose Tolerance Test in Polycystic Ovary Syndrome and Menopausal Patients
M Ciampelli, F Leoni, F Cucinelli, S Mancuso, S Panunzi, AD Gaetano, A Lanzone
The Journal of clinical endocrinology and metabolism 2005
System Modeling and Optimization
J Cagnol, JP Zolésio
2005
In Vivo Fluorescence Detection of Glucose Using a Single-Walled Carbon Nanotube Optical Sensor: Design, Fluorophore Properties, Advantages, and Disadvantages
PW Barone, RS Parker, MS Strano
Analytical Chemistry 2005
Blood Glucose Regulation for Diabetic Mellitus Using a Hybrid Intelligent Techniques
V Nandikolla, D Naidu
2005
High normal 2-hour plasma glucose is associated with insulin sensitivity and secretion that may predispose to type 2 diabetes
ME Pich, S Lemieux, L Prusse, SJ Weisnagel
Diabetologia 2005
Parallel manifestation of insulin resistance and beta cell decompensation is compatible with a common defect in Type 2 diabetes
D Tripathy, KF Eriksson, M Orho-Melander, J Fredriksson, G Ahlqvist, L Groop
Diabetologia 2004
Control of glycaemia: from molecules to men. Minkowski Lecture 2003
M Stumvoll
Diabetologia 2004
Beta-cell failure in the pathogenesis of type 2 diabetes mellitus
JH Steppel, ES Horton
Current Diabetes Reports 2004
IRIS II study: the IRIS II score-assessment of a new clinical algorithm for the classification of insulin resistance in patients with Type 2 diabetes
T Forst, E Standl, C Hohberg, T Konrad, J Schulze, HJ Strotmann, G Lubben, S Pahler, A Bachinger, M Langenfeld, A Pfutzner
Diabetic Medicine 2004
Effect of Some Water Pollutants on the Biology of the Nile Bolti, Oreochromis niloticus
KK .
Pakistan Journal of Biological Sciences 2004
Niacin in HIV-Infected Individuals with Hyperlipidemia Receiving Potent Antiretroviral Therapy
MT Gerber, KE Mondy, KE Yarasheski, H Drechsler, S Claxton, J Stoneman, D DeMarco, WG Powderly, P Tebas
Clinical Infectious Diseases 2004
Body mass index is the most important determining factor for the degree of insulin resistance in non-obese type 2 diabetic patients in Korea
SA Chang, HS Kim, KH Yoon, SH Ko, HS Kwon, SR Kim, WC Lee, SJ Yoo, HS Son, BY Cha, KW Lee, HY Son, SK Kang
Metabolism 2004
Chronopharmaceutics: gimmick or clinically relevant approach to drug delivery?
BB Youan
Journal of Controlled Release 2004
Genetic contributions to glucose intolerance in polycystic ovary syndrome
DA Ehrmann
Reproductive BioMedicine Online 2004
Patterns of insulin resistance in the general population of southeast Spain
G Rojo-Martı́nez, I Esteva, SR de Adana, M Catalá, MJ Merelo, F Tinahones, JM Gómez-Zumaquero, AL Cuesta, F Cardona, F Soriguer
Diabetes Research and Clinical Practice 2004
Blood glucose control for type I diabetes mellitus: A robust tracking H∞ problem
E Ruiz-Velázquez, R Femat, DU Campos-Delgado
Control Engineering Practice 2004
Automated Insulin Infusion Trials in the Intensive Care Unit
CV Doran, JG Chase, GM Shaw, KT Moorhead, NH Hudson
Diabetes Technology & Therapeutics 2004
Derivative weighted active insulin control modelling and clinical trials for ICU patients
CV Doran, NH Hudson, KT Moorhead, JG Chase, GM Shaw, CE Hann
Medical engineering & physics 2004
Impaired  -cell compensation to dexamethasone-induced hyperglycemia in women with polycystic ovary syndrome
DA Ehrmann
American journal of physiology. Endocrinology and metabolism 2004
Effect of lowering postprandial hyperglycemia on insulin secretion in older people with impaired glucose tolerance
AM Chang, MJ Smith, CJ Bloem, AT Galecki, JB Halter
American journal of physiology. Endocrinology and metabolism 2004
INS VNTR is a QTL for the insulin response to oral glucose in obese children
CD Santos, D Fallin, CL Stunff, S LeFur, P Bougnères
Physiological genomics 2004
Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion
H Wang, WS Chu, T Lu, SJ Hasstedt, PA Kern, SC Elbein
American journal of physiology. Endocrinology and metabolism 2004
Expression of FOXC2 in adipose and muscle and its association with whole body insulin sensitivity
GB di Gregorio, R Westergren, S Enerback, T Lu, PA Kern
American journal of physiology. Endocrinology and metabolism 2004
First-phase insulin secretion: does it exist in real life? Considerations on shape and function
A Caumo, L Luzi
American journal of physiology. Endocrinology and metabolism 2004
Enhanced IMC for Glucose Control in Type I Diabetic Patients
Y Ramprasad, GP Rangaiah, S Lakshminarayanan
IFAC Proceedings Volumes 2004
Integration of Biological Systems Content into the Process Dynamics and Control Curriculum
RS Parker, FJ Doyle, MA Henson
IFAC Proceedings Volumes 2004
Canine and Feline Diabetes Mellitus: Nature or Nurture?
JS Rand, LM Fleeman, HA Farrow, DJ Appleton, R Lederer
The Journal of nutrition 2004
Increased n−6 polyunsaturated fatty acids do not attenuate the effects of long-chain n−3 polyunsaturated fatty acids on insulin sensitivity or triacylglycerol reduction in Indian Asians
LM Brady, SS Lovegrove, SV Lesauvage, BA Gower, AM Minihane, CM Williams, JA Lovegrove
The American journal of clinical nutrition 2004
Impaired Glucose Tolerance and Reduced β-Cell Function in Overweight Latino Children with a Positive Family History for Type 2 Diabetes
MI Goran, RN Bergman, Q Avila, M Watkins, GD Ball, GQ Shaibi, MJ Weigensberg, ML Cruz
The Journal of clinical endocrinology and metabolism 2004
Association between a deletion/insertion polymorphism in the ?2B-adrenergic receptor gene and insulin secretion and Type 2 diabetes. The Finnish Diabetes Prevention Study
N Siitonen, J Lindstrm, J Eriksson, TT Valle, H Hmlinen, P Ilanne-Parikka, S Keinnen-Kiukaanniemi, J Tuomilehto, M Laakso, M Uusitupa
Diabetologia 2004
Beta cell function and its relation to insulin action in humans: a critical appraisal
E Ferrannini, A Mari
Diabetologia 2004
The Role of Glucose Allostasis in Type 2 Diabetes
M Stumvoll, PA Tataranni, C Bogardus
Reviews in Endocrine and Metabolic Disorders 2004
Prolonged increase of plasma non-esterified fatty acids fully abolishes the stimulatory effect of 24 hours of moderate hyperglycaemia on insulin sensitivity and pancreatic beta-cell function in obese men
N Leung, T Sakaue, A Carpentier, K Uffelman, A Giacca, GF Lewis
Diabetologia 2004
International Textbook of Diabetes Mellitus
RA DeFronzo, L Mandarino, E Ferrannini
International Textbook of Diabetes Mellitus 2003
Dietary Restriction and Beta-Cell Sensitivity to Glucose in Adult Male Rhesus Monkeys
TA Gresl, RJ Colman, TC Havighurst, DB Allison, DA Schoeller, JW Kemnitz
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2003
Insulin resistance and beta-cell dysfunction in normoglycaemic European women with a history of gestational diabetes
E Kousta, NJ Lawrence, IF Godsland, A Penny, V Anyaoku, BA Millauer, E Cela, DG Johnston, S Robinson, MI McCarthy
Clinical Endocrinology 2003
Insulin resistance is a poor predictor of type 2 diabetes in individuals with no family history of disease
AB Goldfine, C Bouche, RA Parker, C Kim, A Kerivan, JS Soeldner, BC Martin, JH Warram, CR Kahn
Proceedings of the National Academy of Sciences 2003
Presence of impaired insulin secretion and insulin resistance in normoglycemic male subjects with family history of type 2 diabetes
E Ryder, ME Gómez, V Fernández, G Campos, LM Morales, H Valbuena, X Raleigh
Diabetes Research and Clinical Practice 2003
Improvements in insulin sensitivity and beta-cell function (HOMA) with weight loss in the severely obese
JB Dixon, AF Dixon, PE O'Brien
Diabetic Medicine 2003
Pharmacodynamics of NN2211, a novel long acting GLP-1 derivative
H Agersø, P Vicini
European Journal of Pharmaceutical Sciences 2003
Lipodystrophy in human immunodeficiency virus patients impairs insulin action and induces defects in β-cell function
O Andersen, SB Haugaard, UB Andersen, N Friis-Møller, H Storgaard, A Vølund, JO Nielsen, J Iversen, S Madsbad
Metabolism 2003
Insulin secretion after short- and long-term low-grade free fatty acid infusion in men with increased risk of developing type 2 diabetes
H Storgaard, CB Jensen, AA Vaag, A Vølund, S Madsbad
Metabolism 2003
The impact of ethnicity on type 2 diabetes
N Abate, M Chandalia
Journal of Diabetes and its Complications 2003
Contributions of Insulin-Resistance and Insulin-Secretory Defects to the Pathogenesis of Type 2 Diabetes Mellitus
JE Gerich
Mayo Clinic Proceedings 2003
Methods for clinical assessment of insulin sensitivity and β-cell function
G Pacini, A Mari
Best Practice & Research Clinical Endocrinology & Metabolism 2003
Signals adapting the beta cells to changes in insulin sensitivity
B Ahrén, G Pacini
International Congress Series 2003
Genomic scan of glucose and insulin metabolism phenotypes: the HERITAGE Family Study
P An, Y Hong, SJ Weisnagel, T Rice, T Rankinen, AS Leon, JS Skinner, JH Wilmore, YC Chagnon, RN Bergman, C Bouchard, DC Rao
Metabolism 2003
Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study
A Gastaldelli, E Ferrannini, Y Miyazaki, M Matsuda, RA DeFronzo,
Diabetologia 2003
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes
SE Kahn
Diabetologia 2003
Improved β-cell function after standardized weight reduction in severely obese subjects
M Guldstrand, B Ahrén, U Adamson
American journal of physiology. Endocrinology and metabolism 2003
Familiality of metabolic abnormalities is dependent on age at onset and phenotype of the type 2 diabetic proband
D Tripathy, E Lindholm, B Isomaa, C Saloranta, T Tuomi, L Groop
American journal of physiology. Endocrinology and metabolism 2003
Insulin sensitivity and glucose effectiveness from three minimal models: effects of energy restriction and body fat in adult male rhesus monkeys
TA Gresl, RJ Colman, TC Havighurst, LO Byerley, DB Allison, DA Schoeller, JW Kemnitz
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2003
A Robust Approach to Control Blood Glucose Level: Diabetes Mellitus Type I
E Ruiz-Velázquez, DU Campos-Delgado, R Femat
IFAC Proceedings Volumes 2003
Sugars, insulin sensitivity, and the postprandial state
M Daly
The American journal of clinical nutrition 2003
Obesity and diet affect glucose dynamics and insulin sensitivity in Thoroughbred geldings1
RM Hoffman, RC Boston, D Stefanovski, DS Kronfeld, PA Harris
Journal of animal science 2003
Peroxisome Proliferator-Activated Receptor-α Activation during Pregnancy Attenuates Glucose-Stimulated Insulin Hypersecretion in Vivo by Increasing Insulin Sensitivity, without Impairing Pregnancy-Induced Increases in β-Cell Glucose Sensing and Responsiveness
MC Sugden, GK Greenwood, ND Smith, MJ Holness
Endocrinology 2003
Diabetogenic Impact of Long-Chain ω-3 Fatty Acids on Pancreatic β-Cell Function and the Regulation of Endogenous Glucose Production
MJ Holness, GK Greenwood, ND Smith, MC Sugden
Endocrinology 2003
Enhanced Granulosa Cell Responsiveness to Follicle-Stimulating Hormone during Insulin Infusion in Women with Polycystic Ovary Syndrome Treated with Pioglitazone
MS Coffler, K Patel, MH Dahan, RY Yoo, PJ Malcom, RJ Chang
The Journal of clinical endocrinology and metabolism 2003
Mathematical Modeling in Nutrition and the Health Sciences
JA Novotny, MH Green, RC Boston
2003
Insulin sensitivity and cardiovascular risk factors in hypertensive and normotensive native Ghanaians
AG Amoah, DP Schuster, T Gaillard, K Osei
Diabetologia 2003
The evolution of beta-cell dysfunction and insulin resistance in type 2 diabetes
RN Bergman, DT Finegood, SE Kahn
European Journal of Clinical Investigation 2002
Role of insulin resistance and insulin secretory dysfunction in the pathogenesis of type 2 diabetes mellitus: lessons from cross-sectional, prospective, and longitudinal studies in Pima Indians
C Weyer, RE Pratley, PA Tataranni
Current Opinion in Endocrinology & Diabetes 2002
Early disturbances in insulin secretion in the development of type 2 diabetes mellitus
TW van Haeften
Molecular and Cellular Endocrinology 2002
Progression from IGT to type 2 diabetes mellitus: The central role of impaired early insulin secretion
RE Pratley, C Weyer
Current Diabetes Reports 2002
Estimation of plasma insulin from plasma glucose
C Neatpisarnvanit, JR Boston
IEEE Transactions on Biomedical Engineering 2002
Insulin secretion and sensitivity in space flight
BW Tobin, PN Uchakin, SK Leeper-Woodford
Nutrition 2002
Effects of insulin resistance and insulin secretion on the efficacy of interventions to retard development of type 2 diabetes mellitus: the DA Qing IGT and Diabetes Study
G Li, Y Hu, W Yang, Y Jiang, J Wang, J Xiao, Z Hu, X Pan, BV Howard, PH Bennett
Diabetes Research and Clinical Practice 2002
Insulin resistance: a metabolic link between depressive disorder and atherosclerotic vascular diseases
R Ramasubbu
Medical Hypotheses 2002
Effect of Changes in Fat Distribution on the Rates of Change of Insulin Response in Children
TT Huang, MS Johnson, BA Gower, MI Goran
Obesity research 2002
Variations in Insulin Secretion in Carriers of the E23K Variant in the KIR6.2 Subunit of the ATP-Sensitive K+ Channel in the  -Cell
LM Hart, TW van Haeften, JM Dekker, M Bot, RJ Heine, JA Maassen
Diabetes 2002
 -Cell Function Is a Major Contributor to Oral Glucose Tolerance in High-Risk Relatives of Four Ethnic Groups in the U.S
CC Jensen, M Cnop, RL Hull, WY Fujimoto, SE Kahn
Diabetes 2002
Decline in insulin action with age in endurance-trained humans
CM Clevenger, PP Jones, H Tanaka, DR Seals, CA DeSouza
Journal of applied physiology 2002
Insufficient islet compensation to insulin resistance vs. reduced glucose effectiveness in glucose-intolerant mice
B Ahrén, G Pacini
American journal of physiology. Endocrinology and metabolism 2002
Prospective, Intensive Study of Metabolic Changes Associated with 48 Weeks of Amprenavir‐Based Antiretroviral Therapy
MP Dubé, D Qian, H EdmondsonMelançon, FR Sattler, D Goodwin, C Martinez, V Williams, D Johnson, TA Buchanan
Clinical Infectious Diseases 2002
Oat Consumption Does Not Affect Resting Casual and Ambulatory 24-h Arterial Blood Pressure in Men with High-Normal Blood Pressure to Stage I Hypertension
BM Davy, CL Melby, SD Beske, RC Ho, LR Davrath, KP Davy
The Journal of nutrition 2002
Effects of weight loss on changes in insulin sensitivity and lipid concentrations in premenopausal African American and white women
BA Gower, RL Weinsier, JM Jordan, GR Hunter, R Desmond
The American journal of clinical nutrition 2002
High-fiber oat cereal compared with wheat cereal consumption favorably alters LDL-cholesterol subclass and particle numbers in middle-aged and older men
BM Davy, KP Davy, RC Ho, SD Beske, LR Davrath, CL Melby
The American journal of clinical nutrition 2002
Contribution of Insulin Secretion and Clearance to Glucose-Induced Insulin Concentration in African-American and Caucasian Children
BA Gower, WM Granger, F Franklin, RM Shewchuk, MI Goran
The Journal of clinical endocrinology and metabolism 2002
Assessment of beta-cell function during the oral glucose tolerance test by a minimal model of insulin secretion
A Cretti, M Lehtovirta, E Bonora, B Brunato, MG Zenti, F Tosi, M Caputo, B Caruso, LC Groop, M Muggeo, RC Bonadonna
European Journal of Clinical Investigation 2001
Postprandial triglyceride-rich lipoprotein metabolism and insulin sensitivity in nonalcoholic steatohepatitis patients
M Cassader, R Gambino, G Musso, N Depetris, F Mecca, P Cavallo-Perin, G Pacini, M Rizzetto, G Pagano
Lipids 2001
Impact of cyclosporine and low-dose steroid therapy on insulin sensitivity and beta-cell function in patients with longterm liver grafts
T Konrad, C Lakos, K Viehmann, KH Usadel, B Markus, C Allers, E Hanisch, A Encke, P Vicini, G Toffolo, C Cobelli
Transplant International 2001
Familial resemblance for glucose and insulin metabolism indices derived from an intravenous glucose tolerance test in Blacks and Whites of the HERITAGE Family Study
Y Hong, SJ Weisnagel, T Rice, G Sun, SA Mandel, C Gu, T Rankinen, J Gagnon, AS Leon, JS Skinner, JH Wilmore, RN Bergman, C Bouchard, DC Rao
Clinical Genetics 2001
β-cell deterioration - prospects for reversal or prevention
DT Finegood, BG Topp
Diabetes, Obesity and Metabolism 2001
Prospective Evaluation of the Effect of Initiating Indinavir-Based Therapy on Insulin Sensitivity and B-Cell Function in HIV-Infected Patients
MP Dubé, H Edmondson-Melançon, D Qian, R Aqeel, D Johnson, TA Buchanan
JAIDS Journal of Acquired Immune Deficiency Syndromes 2001
Insulin secretion, obesity, and potential behavioral influences: results from the Insulin Resistance Atherosclerosis Study (IRAS)
EJ Mayer-Davis, S Levin, RN Bergman, RB D'Agostino, AJ Karter, MF Saad
Diabetes/Metabolism Research and Reviews 2001
Prospective Evaluation of the Effect of Initiating Indinavir-Based Therapy on Insulin Sensitivity and B-Cell Function in HIV-Infected Patients:
MP Dubé, H Edmondson-Melançon, D Qian, R Aqeel, D Johnson, TA Buchanan
JAIDS Journal of Acquired Immune Deficiency Syndromes 2001
Familial resemblance for glucose and insulin metabolism indices derived from an intravenous glucose tolerance test in Blacks and Whites of the HERITAGE Family Study: Heritability of glucose homeostasis from IVGTT
Y Hong, SJ Weisnagel, T Rice, G Sun, SA Mandel, C Gu, T Rankinen, J Gagnon, AS Leon, JS Skinner, JH Wilmore, RN Bergman, C Bouchard, DC Rao
Clinical Genetics 2001
Insulin sensitivity and beta-cell secretion after liver transplantation in patients with acute liver failure
T Konrad, M Golling, P Vicini, G Toffolo, M Wittman, A Mahon, E Klar, C Cobelli, KH Usadel
Transplantation Proceedings 2001
Influence of Total vs. Visceral Fat on Insulin Action and Secretion in African American and White Children
MI Goran, RN Bergman, BA Gower
Obesity research 2001
Anti-lipolytic Effects of Insulin in African American and White Prepubertal Boys
BA Gower, SL Herd, MI Goran
Obesity research 2001
Insulin and C-peptide secretion and kinetics in humans: direct and model-based measurements during OGTT
A Tura, B Ludvik, JJ Nolan, G Pacini, K Thomaseth
American journal of physiology. Endocrinology and metabolism 2001
Contribution to glucose tolerance of insulin-independent vs. insulin-dependent mechanisms in mice
G Pacini, K Thomaseth, B Ahrén
American journal of physiology. Endocrinology and metabolism 2001
Insulin Sensitivity Decreases with Obesity, and Lean Cats with Low Insulin Sensitivity are at Greatest Risk of Glucose Intolerance with Weight Gain
DJ Appleton, JS Rand, GD Sunvold
Journal of Feline Medicine & Surgery 2001
Obesity, Body Fat Distribution, Insulin Sensitivity and Islet β-Cell Function as Explanations for Metabolic Diversity
SE Kahn, RL Prigeon, RS Schwartz, WY Fujimoto, RH Knopp, JD Brunzell, D Porte
The Journal of nutrition 2001
A Mathematical Model Describing the Glycemic Response of Diabetic Patients to Meal and i.v. Infusion of Insulin
PG Fabietti, G Calabrese, M Iorio, S Bistoni, P Brunetti, E Sarti, MM Benedetti
The International Journal of Artificial Organs 2001
Genetics of Diabetes Mellitus
WL Lowe
2001
The Importance of β-Cell Failure in the Development and Progression of Type 2 Diabetes
SE Kahn
The Journal of clinical endocrinology and metabolism 2001
Insulin sensitivity decreases with obesity, and lean cats with low insulin sensitivity are at greatest risk of glucose intolerance with weight gain.
Appleton DJ, Rand JS, Sunvold GD
Journal of feline medicine and surgery 2001
A novel hyperglycaemic clamp for characterization of islet function in humans: assessment of three different secretagogues, maximal insulin response and reproducibility
Fritsche, Stefan, Hardt, Schutzenauer, Haring, Stumvoll
European Journal of Clinical Investigation 2000
The long term health consequences of polycystic ovary syndrome
CJ Kelly, JM Connell, IT Cameron, GW Gould, H Lyall
BJOG: An International Journal of Obstetrics and Gynaecology 2000
The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. II. An autosomal genome scan for diabetes-related quantitative-trait loci
RM Watanabe, S Ghosh, CD Langefeld, TT Valle, ER Hauser, VL Magnuson, KL Mohlke, K Silander, DS Ally, P Chines, J Blaschak-Harvan, JA Douglas, WL Duren, MP Epstein, TE Fingerlin, HS Kaleta, EM Lange, C Li, RC McEachin, HM Stringham, E Trager, PP White, J Balow, G Birznieks, J Chang, W Eldridge
The American Journal of Human Genetics 2000
Glucose regulation in captivePongo pygmaeus abeli, P. p. pygmaeus,andP. p. abeli x P. p. pygmaeusorangutans
TA Gresl, ST Baum, JW Kemnitz
Zoo Biology 2000
Islet Phospholipase A2 Activation Is Potentiated in Insulin Resistant Mice
E Simonsson, S Karlsson, B Ahrén
Biochemical and Biophysical Research Communications 2000
The Finland–United States Investigation of Non–Insulin-Dependent Diabetes Mellitus Genetics (FUSION) Study. II. An Autosomal Genome Scan for Diabetes-Related Quantitative-Trait Loci
RM Watanabe, S Ghosh, CD Langefeld, TT Valle, ER Hauser, VL Magnuson, KL Mohlke, K Silander, DS Ally, P Chines, J Blaschak-Harvan, JA Douglas, WL Duren, MP Epstein, TE Fingerlin, HS Kaleta, EM Lange, C Li, RC McEachin, HM Stringham, E Trager, PP White, J Balow, G Birznieks, J Chang, W Eldridge, MR Erdos, ZE Karanjawala, JI Knapp, K Kudelko, C Martin, A Morales-Mena, A Musick, T Musick, C Pfahl, R Porter, JB Rayman, D Rha, L Segal, S Shapiro, R Sharaf, B Shurtleff, A So, J Tannenbaum, C Te, J Tovar, A Unni, C Welch, R Whiten, A Witt, K Kohtamäki, C Ehnholm, J Eriksson, L Toivanen, G Vidgren, SJ Nylund, E Tuomilehto-Wolf, EH Ross, E Demirchyan, WA Hagopian, TA Buchanan, J Tuomilehto, RN Bergman, FS Collins, M Boehnke
The American Journal of Human Genetics 2000
RobustH∞ glucose control in diabetes using a physiological model
RS Parker, FJ Doyle, JH Ward, NA Peppas
AIChE Journal 2000
Evidence for impaired glucose effectiveness in cirrhotic patients after liver transplantation
T Konrad, T Steinmüller, P Vicini, G Toffolo, D Grewerus, A Schüller, WO Bechstein, KH Usadel, C Cobelli, A Mahon, W Wittmann, E Klar, M Golling, P Neuhaus
Metabolism 2000
Addressing the insulin secretion defect: A logical first-line approach
JE Gerich
Metabolism 2000
A Model of β -Cell Mass, Insulin, and Glucose Kinetics: Pathways to Diabetes
B Topp, K Promislow, G Devries, RM Miura, DT Finegood
Journal of Theoretical Biology 2000
Diabetes Information Technology & WebWatch
ED Lehmann
Diabetes Technology & Therapeutics 2000
Evaluation of factors controlling glucose tolerance in patients with HCV infection before and after 4 months therapy with interferon-alpha
Konrad, Zeuzem, Vicini, Toffolo, Briem, Lormann, Herrmann, Berger, Kusterer, Teuber, Cobelli, Usadel
European Journal of Clinical Investigation 2000
Diabetes Information Technology & WebWatch
ED Lehmann
Diabetes Technology & Therapeutics 2000
REGULATION OF GLUCOSE TOLERANCE IN PATIENTS AFTER LIVER TRANSPLANTATION: Impact of Cyclosporin versus Tacrolimus Therapy1
T Konrad, T Steinmller, P Vicini, G Toffolo, D Grewerus, A Schller, WO Bechstein, KH Usadel, C Cobelli, P Neuhaus
Transplantation 2000
Role of dietary factors in ethnic differences in early risk of cardiovascular disease and type 2 diabetes
CH Lindquist, BA Gower, MI Goran
The American journal of clinical nutrition 2000
The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus
C Weyer, C Bogardus, DM Mott, RE Pratley
Journal of Clinical Investigation 1999
Controlled oral glucose tolerance test: evaluation of insulin resistance with an insulin infusion algorithm that forces the OGTT glycaemic curve within the normal range. A feasibility study
Volpicelli, Iannello, Belfiore
Clinical Physiology 1999
Is insulin resistance the principal cause of type 2 diabetes?
JE Gerich
Diabetes, Obesity and Metabolism 1999
Mechanisms for Hyperglycemia in the Metabolic Syndrome: The Key Role of beta-Cell Dysfunction
D Porte
Annals of the New York Academy of Sciences 1999
Endothelial and metabolic characteristics of patients with angina and angiographically normal coronary arteries
PM Piatti, G Fragasso, LD Monti, A Caumo, CV Phan, G Valsecchi, S Costa, E Fochesato, G Pozza, AE Pontiroli, S Chierchia
Journal of the American College of Cardiology 1999
Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs
S Ghosh, RM Watanabe, ER Hauser, T Valle, VL Magnuson, MR Erdos, CD Langefeld, J Balow, DS Ally, K Kohtamaki, P Chines, G Birznieks, HS Kaleta, A Musick, C Te, J Tannenbaum, W Eldridge, S Shapiro, C Martin, A Witt, A So, J Chang, B Shurtleff, R Porter, K Kudelko, A Unni, L Segal, R Sharaf, J Blaschak-Harvan, J Eriksson, T Tenkula, G Vidgren, C Ehnholm, E Tuomilehto-Wolf, W Hagopian, TA Buchanan, J Tuomilehto, RN Bergman, FS Collins, M Boehnke
Proceedings of the National Academy of Sciences 1999
Metabolic and fibrinolytic response to changed insulin sensitivity in users of oral contraceptives
KR Petersen, E Christiansen, S Madsbad, SO Skouby, LF Andersen, J Jespersen
Contraception 1999
Comparison of a Radioimmunoassay with a Microparticle Enzyme Immunoassay of Insulin for Use with the Minimal Model Method of Determining Whole-Body Insulin Sensitivity
JC Rood, JC Lovejoy, RT Tulley
Diabetes Technology & Therapeutics 1999
Reduced β-cell function contributes to impaired glucose tolerance in dogs made obese by high-fat feeding
KJ Kaiyala, RL Prigeon, SE Kahn, SC Woods, D Porte, MW Schwartz
American journal of physiology. Endocrinology and metabolism 1999
Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation
A Carpentier, SD Mittelman, B Lamarche, RN Bergman, A Giacca, GF Lewis
American journal of physiology. Endocrinology and metabolism 1999
Dose-related effects of GLP-1 on insulin secretion, insulin sensitivity, and glucose effectiveness in mice
B Ahrén, G Pacini
American journal of physiology. Endocrinology and metabolism 1999
Whole body glucose metabolism
K Zierler
American journal of physiology. Endocrinology and metabolism 1999
Undermodeling affects minimal model indexes: insights from a two-compartment model
A Caumo, P Vicini, JJ Zachwieja, A Avogaro, K Yarasheski, DM Bier, C Cobelli
American journal of physiology. Endocrinology and metabolism 1999
Increased insulin secretion and normalization of glucose tolerance by cholinergic agonism in high fat-fed mice
B Ahrén, P Sauerberg, C Thomsen
American journal of physiology. Endocrinology and metabolism 1999
Insulin resistance and hyperinsulinemia are already present in patients with incipient renal disease
D Fliser, G Pacini, R Engelleiter, A Kautzky-Willer, R Prager, E Franek, E Ritz
Kidney International 1998
Insulin Sensitivity Indices Calculated from Basal and OGTT-Induced Insulin, Glucose, and FFA Levels
F Belfiore, S Iannello, G Volpicelli
Molecular Genetics and Metabolism 1998
Potentiated β-cell response to non-glucose stimuli in insulin-resistant C57BL/6J mice
E Simonsson, B Ahrén
European Journal of Pharmacology 1998
Circulating leptin did not associate with the development of the hyperglycemia accompanied by insulin insensitivity in spontaneous noninsulin dependent diabetes mellitus model Otsuka–Long–Evans–Tokushima–Fatty rats
M Iida, T Murakami, M Sei, M Kuwajima, M Yamada, T Aono, K Shima
Regulatory Peptides 1998
TRIPOD (TRoglitazone In the Prevention Of Diabetes): A Randomized, Placebo-Controlled Trial of Troglitazone in Women with Prior Gestational Diabetes Mellitus
SP PhD, RK DSc, KB MD, SK MD, AX PhD, TA MD
Controlled Clinical Trials 1998
Population-based modeling to demonstrate extrapancreatic effects of tolbutamide
A Rostami-Hodjegan, SR Peacey, E George, SR Heller, GT Tucker
American journal of physiology. Endocrinology and metabolism 1998
Insulin sensitivity and glucose effectiveness: minimal model analysis of regular and insulin-modified FSIGT
G Pacini, G Tonolo, M Sambataro, M Maioli, M Ciccarese, E Brocco, A Avogaro, R Nosadini
American journal of physiology. Endocrinology and metabolism 1998
Critical evaluation of the combined model approach for estimation of prehepatic insulin secretion
RM Watanabe, GM Steil, RN Bergman
American journal of physiology. Endocrinology and metabolism 1998
PACAP stimulates insulin secretion but inhibits insulin sensitivity in mice
K Filipsson, G Pacini, AJ Scheurink, B Ahrén
American journal of physiology. Endocrinology and metabolism 1998
Human aging is associated with parallel reductions in insulin and amylin release
CJ Dechenes, CB Verchere, S Andrikopoulos, SE Kahn
American journal of physiology. Endocrinology and metabolism 1998
Insulin Resistance and Preeclampsia
KM Berkowitz
Clinics in Perinatology 1998
The Genetic Basis of Type 2 Diabetes Mellitus: Impaired Insulin Secretion versus Impaired Insulin Sensitivity
JE Gerich
Endocrine reviews 1998
Insulin Resistance
DC Whitelaw, SG Gilbey
Annals of Clinical Biochemistry 1998
Treatment with the oral antidiabetic agent troglitazone improves beta cell responses to glucose in subjects with impaired glucose tolerance
MK Cavaghan, DA Ehrmann, MM Byrne, KS Polonsky
Journal of Clinical Investigation 1997
Regulation of circulating leptin in humans
B Ahrén, H Larsson, C Wilhelmsson, B Näsman, T Olsson
Endocrine 1997
Quantification of the effects of troglitazone on insulin sensitivity and β-cell function in Watanabe heritable hyperlipidemic rabbits: A minimal model analysis
B Zhang, K Saku, K Arakawa
Metabolism 1997
Glucose metabolism in severe malaria: Minimal model analysis of the intravenous glucose tolerance test incorporating a stable glucose label
TQ Binh, TM Davis, W Johnston, LT Thu, R Boston, PT Danh, TK Anh
Metabolism 1997
Plasma leptin levels, insulin secretion, clearance and action on glucose metabolism in anorexia nervosa
MR Letiexhe, AJ Scheen, PJ Lefèbvre
Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity 1997
Interactive educational simulators in diabetes care
ED Lehmann
Informatics for Health and Social Care 1997
A Prospective Study of Insulin Sensitivity and Glucose Metabolism in Women Using a Continuous Subdermal Levonorgestrel Implant System
MA Harper, PJ Meis, L Steele
Journal of the Society for Gynecologic Investigation 1997
Clinical Research in Diabetes and Obesity
B Draznin, R Rizza
1997
Insulin Resistance and the Polycystic Ovary Syndrome: Mechanism and Implications for Pathogenesis*
A Dunaif
Endocrine reviews 1997
Plasma leptin levels, insulin secretion, clearance and action on glucose metabolism in anorexia nervosa
MR Letiexhe, AJ Scheen, PJ Lefèbvre
Eating and weight disorders : EWD 1997
Elimination of the action of glucagon-like peptide 1 causes an impairment of glucose tolerance after nutrient ingestion by healthy baboons
DA D'Alessio, R Vogel, R Prigeon, E Laschansky, D Koerker, J Eng, JW Ensinck
Journal of Clinical Investigation 1996
Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population-based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and life-style factors
JO Clausen, K Borch-Johnsen, H Ibsen, RN Bergman, P Hougaard, K Winther, O Pedersen
Journal of Clinical Investigation 1996
Measurement of glucose metabolism and insulin secretion during normal pregnancy and pregnancy complicated by gestational diabetes
SB Bowes, TR Hennessy, AM Umpleby, JJ Benn, NC Jackson, MA Boroujerdi, PH Sönksen, C Lowy
Diabetologia 1996
Is the minimal model too minimal?
A Caumo, P Vicini, C Cobelli
Diabetologia 1996
Islet dysfunction in obese women with impaired glucose tolerance
H Larsson, B Ahrén
Metabolism 1996
Abdominal fat distribution and metabolic risk factors: Effects of race
JC Lovejoy, JA de la Bretonne, M Klemperer, R Tulley
Metabolism 1996
β-cell activity and hepatic insulin extraction following dexamethasone administration in healthy subjects
A Kautzky-Willer, K Thomaseth, M Clodi, B Ludvik, W Waldhäusl, R Prager, G Pacini
Metabolism 1996
Non-Insulin-Dependent Diabetes Mellitus — A Genetically Programmed Failure of the Beta Cell to Compensate for Insulin Resistance
JS Flier, LH Underhill, KS Polonsky, J Sturis, GI Bell
New England Journal of Medicine 1996
Integrated mathematical model to assess beta-cell activity during the oral glucose test
K Thomaseth, A Kautzky-Willer, B Ludvik, R Prager, G Pacini
American journal of physiology. Endocrinology and metabolism 1996
The hot but not the cold minimal model allows precise assessment of insulin sensitivity in NIDDM subjects
A Avogaro, P Vicini, A Valerio, A Caumo, C Cobelli
American journal of physiology. Endocrinology and metabolism 1996
Failure to adequately adapt reduced insulin sensitivity with increased insulin secretion in women with impaired glucose tolerance
H Larsson, B Ahrn
Diabetologia 1996
Insulin secretory defects in polycystic ovary syndrome. Relationship to insulin sensitivity and family history of non-insulin-dependent diabetes mellitus
DA Ehrmann, J Sturis, MM Byrne, T Karrison, RL Rosenfield, KS Polonsky
Journal of Clinical Investigation 1995
Intravenous calcitriol normalizes insulin sensitivity in uremic patients
A Kautzky-Willer, G Pacini, U Barnas, B Ludvik, C Streli, H Graf, R Prager
Kidney International 1995
Effects of oral zinc gluconate on glucose effectiveness and insulin sensitivity in humans
JF Brun, R Guintrand-Hugret, C Fons, J Carvajal, C Fedou, M Fussellier, L Bardet, A Orsetti
Biological Trace Element Research 1995
Insulin sensitivity is unaltered by the use of the Norplant subdermal implant contraceptive
T Koopersmith, R Lobo
Contraception 1995
Insulin resistance and hyperinsulinemia in homozygous β-thalassemia
P Cavallo-Perin, G Pacini, F Cerutti, A Bessone, C Condo, L Sacchetti, A Piga, G Pagano
Metabolism 1995
Insulin secretion in insulin-resistant women with a history of gestational diabetes
MM Byrne, JS O'Meara, KS Polonsky
Metabolism 1995
Effects of metformin in obese patients with impaired glucose tolerance
AJ Scheen, MR Letiexhe, PJ Lefèbvre
Diabetes/Metabolism Reviews 1995
Short Administration of Metformin Improves Insulin Sensitivity in Android Obese Subjects with Impaired Glucose Tolerance
AJ Scheen, MR Letiexhe, PJ Lefèbvre
Diabetic Medicine 1995
Insulin sensitivity is unaltered by the use of the Norplant® subdermal implant contraceptive
TB Koopersmith, RA Lobo
Contraception 1995
How to measure insulin action in vivo
AJ Scheen, N Paquot, MJ Castillo, PJ Lefèbvre
Diabetes / Metabolism Reviews 1994
Role of islet amyloid polypeptide secretion in insulin-resistant humans
A Kautzky-Willer, K Thomaseth, G Pacini, M Clodi, B Ludvik, C Streli, W Waldhäusl, R Prager
Diabetologia 1994
Insulin sensitivity, insulin secretion, and glucose effectiveness in subjects with impaired glucose tolerance: A minimal model analysis
A Taniguchi, Y Nakai, M Fukushima, H Imura, H Kawamura, I Nagata, GL Florant, K Tokuyama
Metabolism 1994
β-cell response and insulin hepatic extraction in noncirrhotic alcoholic patients soon after withdrawal
MG Piccardo, G Pacini, E Nardi, MS Rosa, RD Vito
Metabolism 1994
Mathematical models of insulin secretion in physiological and clinical investigations
G Pacini
Computer Methods and Programs in Biomedicine 1994
Original ArticlesComparison of Estimates of Insulin Sensitivity in Pre- and Postmenopausal Women Using the Insulin Tolerance Test and the Frequently Sampled Intravenous Glucose Tolerance Test
SR Lindheim, TA Buchanan, DM Duffy, MA Vijod, T Kojima, FZ Stanczyk, RA Lobo
Journal of the Society for Gynecologic Investigation 1994
Measurement in Lymph: Metabolic Insights from Sampling the Remote Compartment
RN Bergman, G Steil, M Ader, R Poulin, DC Bradley
IFAC Proceedings Volumes 1994
Role of Insulin Error on Minimal Model Parameter Estimates in Various IVGTT Protocols
A Ruggeri, C Cobelli
IFAC Proceedings Volumes 1994
Fuzzy Logic Control of Plasma Glucose Levels for Insulin Dependent Diabetes
HT Nguyen, D Sands, A Shannon
IFAC Proceedings Volumes 1994
The effect of systemic venous drainage of the pancreas on insulin sensitivity in dogs
J Radziuk, P Barron, H Najm, J Davies
Journal of Clinical Investigation 1993
Insulin resistance, secretion, and elimination in postmenopausal women receiving oral or transdermal hormone replacement therapy
IF Godsland, K Gangar, C Walton, MP Cust, MI Whitehead, V Wynn, JC Stevenson
Metabolism 1993
Insulin sensitivity, insulin secretion, and glucose effectiveness in anorexia nervosa: A minimal model analysis
M Fukushima, Y Nakai, A Taniguchi, H Imura, I Nagata, K Tokuyama
Metabolism 1993
Intravenous glucose tolerance test-derived glucose effectiveness in physically trained humans
K Tokuyama, Y Higaki, J Fujitani, A Kiyonaga, H Tanaka, M Shindo, M Fukushima, Y Nakai, H Imura, I Nagata, et
American journal of physiology. Endocrinology and metabolism 1993
Magnesium deficiency produces insulin resistance and increased thromboxane synthesis
JL Nadler, T Buchanan, R Natarajan, I Antonipillai, R Bergman, R Rude
Hypertension 1993
Elevated hepatic insulin extraction in essential hypertension
A Kautzky-Willer, G Pacini, M Weissel, M Capek, B Ludvik, R Prager
Hypertension 1993
New Concepts in the Pathogenesis of NIDDM
CG Östenson, S Efendić, M Vranic
1993
A Simple Method for Quantitation of Insulin Sensitivity and Insulin Release from an Intravenous Glucose Tolerance Test
P Galvin, G Ward, J Walters, R Pestell, M Koschmann, A Vaag, I Martin, JD Best, F Alford
Diabetic Medicine 1992
Insulin resistance and cigarette smoking
FS Facchini, CB Hollenbeck, J Jeppesen, YD Chen, GM Reaven
The Lancet 1992
Immunoradiometric assay of insulin, intact proinsulin and 32–33 split proinsulin and radioimmunoassay of insulin in diet-treated Type 2 (non-insulin-dependent) diabetic subjects
PM Clark, JC Levy, L Cox, M Burnett, RC Turner, CN Hales
Diabetologia 1992
Insulin secretion, insulin sensitivity and hepatic insulin extraction in primary hyperparathyroidism before and after surgery
A Kautzky-Willer, G Pacinl, B Niederle, G Schernthaner, R Prager
Clinical Endocrinology 1992
The effect of epinephrine on glucose-mediated and insulin-mediated glucose disposal in insulin-dependent diabetes
JM Walters, GM Ward, A Kalfas, JD Best, FP Alford
Metabolism 1992
Insulin and insulin-like growth factor-I responsiveness in polycystic ovarian syndrome**Presented in part at the 36th Annual Meeting of the Society for Gynecologic Investigation, San Diego, California, March 15 to 18, 1989.††Supported in part by the United States Public Health Service grants RR00865, CA30388, and CC32737, Bethesda, Maryland, to the Clinical Research Center, University of California at Los Angeles, Los Angeles, California
RP Buyalos, ME Geffner, N Bersch, HL Judd, RM Watanabe, RN Bergman, DW Golde
Fertility and Sterility 1992
Posthepatic rate of appearance of insulin: measurement and validation in the nonsteady state
T Morishima, S Pye, C Bradshaw, J Radziuk
American journal of physiology. Endocrinology and metabolism 1992
Effect of acitretin on the response to an intravenous glucose tolerance test in healthy volunteers
D Hartmann, I Forgo, UC Dubach, U Hennes
European Journal of Clinical Pharmacology 1992
Comparison of Indices of Islet B-cell Function in Type 2 Diabetes in Relation to Insulin Effectiveness and Clinical Outcome
SW Coppack, V Thursfield, H Dhar, TD Hockaday
Diabetic Medicine 1991
Insulin secretion, insulin sensitivity and glucose-mediated glucose disposal in Cushing's disease: a minimal model analysis
R Page, M Boolell, A Kalfas, S Sawyer, R Pestell, G Ward, F Alford
Clinical Endocrinology 1991
Minimal Models of Glucose Disappearance: Lessons from the Labelled IVGTT
A Caumo, A Giacca, M Morgese, G Pozza, P Micossi, C Cobelli
Diabetic Medicine 1991
The effect of Diamicron® on the secretion and action of insulin
JL Chiasson, P Hamet, M Verdy
Diabetes Research and Clinical Practice 1991
Benfluorex and blood glucose control in non insulin-dependent diabetic patients
P Cavallo-Perin, P Estivi, L Boine, R Galletti, G Pacini, C Cobelli, G Pagano
Journal of Endocrinological Investigation 1991
Distinct but nonadditive effects of epinephrine and cortisol on determinants of glucose tolerance in dogs
IK Martin, MJ Christopher, FP Alford, JD Best
American journal of physiology. Endocrinology and metabolism 1991
Simple empirical assessment of Beta-cell function by a constant infusion of glucose test in normal and Type 2 (non-insulin-dependent) diabetic subjects
JC Levy, A Rudenski, M Burnett, R Knight, DR Matthews, RC Turner
Diabetologia 1991
INSULIN SECRETION, INSULIN SENSITIVITY AND GLUCOSE-MEDIATED GLUCOSE DISPOSAL IN THYROTOXICOSIS: A MINIMAL MODEL ANALYSIS
R Pestell, F Alford, R Ramos, S Sawyer, J Best, G Ward
Clinical Endocrinology 1990
Glucose intolerance in the elderly: an open debate
G Paolisso, M Varricchio, F D'Onofrio
Archives of Gerontology and Geriatrics 1990
A discrete segments approach to the optimization of insulin infusion algorithms
RL Ollerton
Computers & Mathematics with Applications 1990
DIABLOG: a simulation program of insulin-glucose dynamics for education of diabetics
E Biermann, H Mehnert
Computer Methods and Programs in Biomedicine 1990
Estimation of β-cell secretion and insulin hepatic extraction by the minimal modelling technique
G Pacini, C Cobelli
Computer Methods and Programs in Biomedicine 1990
Application of the SAAM modeling program to minimal model analysis of intravenous glucose tolerance test data
IK Martin, KM Weber, GM Ward, JD Best, RC Boston
Computer Methods and Programs in Biomedicine 1990
A program to estimate insulin sensitivity and pancreatic responsivity from an IVGTT using the minimal modeling technique
FJ Vega-Catalan
Computers and Biomedical Research 1990
Glucose disposal, β-cell secretion, and hepatic insulin extraction in cirrhosis: A minimal model assessment
G Marchesini, G Pacini, G Bianchi, D Patrono, C Cobelli
Gastroenterology 1990
Biomedical Advances in Aging
AL Goldstein
1990
Dynamics of Complex Interconnected Biological Systems
TL Vincent, AI Mees, LS Jennings
1990
Assessment of insulin sensitivity in vivo: A critical review
RN Bergman, ID Hope, YJ Yang, RM Watanabe, MA Meador, JH Youn, M Ader
Diabetes / Metabolism Reviews 1989
Application of optimal control theory to diabetes mellitus
RL Ollerton
International Journal of Control 1989
Optimal input design: case study of the metabolic process
R Giladi, S Sideman
Mathematical Biosciences 1989
Menstrual cyclicity has a profound effect on glucose homeostasis*†*Presented in part at the Forty-Fourth Annual Meeting of The American Fertility Society, October 10 to 13, 1988, Atlanta, Georgia.†Supported by grant no. 186280 from the Juvenile Diabetes Foundation to M.P.D. and by grant no. RR00125 from the General Clinical Research Center
MP Diamond, DC Simonson, RA DeFronzo
Fertility and Sterility 1989
A compartmental model to quantitate in vivo glucose transport in the human forearm
C Cobelli, MP Saccomani, E Ferrannini, RA Defronzo, R Gelfand, R Bonadonna
American journal of physiology. Endocrinology and metabolism 1989
Alternative method for minimal model analysis of intravenous glucose tolerance data
KM Weber, IK Martin, JD Best, FP Alford, RC Boston
American journal of physiology. Endocrinology and metabolism 1989
Etiology of Cancer in Man
AS Levine
1989
Glucose disappearance rate in rhesus monkeys: Some technical considerations
KL Jen, BC Hansen
American Journal of Primatology 1988
Hormonal effects of norepinephrine on acute glucose disposal in humans: A minimal model analysis
AG Marangou, FP Alford, G Ward, F Liskaser, PM Aitken, KM Weber, RC Boston, JD Best
Metabolism 1988
2 Role of insulin resistance in the pathogenesis of Type 2 (non-insulin-dependent) diabetes mellitus
JE Gerich
Baillière's Clinical Endocrinology and Metabolism 1988
Identification of Glucose Regulation System Using a Mathematical Model with a Derivative and a Proportional Insulin Secretory Mechanism
H Mori, S Kitamura
IFAC Proceedings Volumes 1988
Effect of insulin on [3H]deoxy-D-glucose pharmacokinetics in the rat
SM Furler, AB Jenkins, EW Kraegen
American journal of physiology. Endocrinology and metabolism 1988
Models for Measuring Hepatic Glucose Production from Labelled IVGTT
A Caumo, P Micossi, C Cobelli
IFAC Proceedings Volumes 1988
Female Contraception
B Runnebaum, T Rabe, L Kiesel
1988
Research Instrumentation for the 21st Century
GR Beecher
1988
Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp
RN Bergman, R Prager, A Volund, JM Olefsky
Journal of Clinical Investigation 1987
Norepinephrine metabolism in humans. Kinetic analysis and model
OA Linares, JA Jacquez, LA Zech, MJ Smith, JA Sanfield, LA Morrow, SG Rosen, JB Halter
Journal of Clinical Investigation 1987
QUANTITATIVE MODELLING OF ENDOCRINE DISEASES AS EXEMPLIFIED BY DIABETES
RC Turner, AS Rudenski, RR Holman, DR Matthews, SP O'rahilly
Clinical Endocrinology 1987
Insulin Resistance in Klinefelter Syndrome
ME Geffner, SA Kaplan, N Bersche, BM Lippe, EM Landow, RN Bergman, DW Golde
Journal of Pediatric Endocrinology and Metabolism 1987
The minimal model of glucose disappearance: optimal input studies
C Cobelli, K Thomaseth
Mathematical Biosciences 1987
6 Insulin sensitivity in the intact organism
M Ader, RN Bergman
Baillière's Clinical Endocrinology and Metabolism 1987
Derivation of a quantitative measure of insulin sensitivity from the intravenous tolbutamide test using the minimal model of glucose dynamics
NM Shennan, IF Godsland, V Wynn
Diabetologia 1987
Homeostasis VII. A conspectus
EA Murphy, RE Pyeritz, JM Opitz, JF Reynolds
American Journal of Medical Genetics 1986
Pathophysiology of malnutrition in the adult cancer patient
D Heber, LO Byerley, J Chi, M Grosvenor, RN Bergman, M Coleman, RT Chlebowski
Cancer 1986
MINMOD: a computer program to calculate insulin sensitivity and pancreatic responsivity from the frequently sampled intravenous glucose tolerance test
G Pacini, RN Bergman
Computer Methods and Programs in Biomedicine 1986
Estimation of insulin sensitivity and glucose clearance from minimal model: new insights from labeled IVGTT
C Cobelli, G Pacini, G Toffolo, L Sacca
American journal of physiology. Endocrinology and metabolism 1986
On linearity of insulin kinetics
C Cobelli, A Mari, E Ferrannini
American journal of physiology. Endocrinology and metabolism 1986
Physiologic and cellular insulin action in a glucose-intolerant model of Type 2 (non-insulin-dependent) diabetes in rats
BL Maloff, BK Boyd
Diabetologia 1986
Receptor defects in patients with extreme insulin resistance
SI Taylor
Diabetes / Metabolism Reviews 1985
Optimal Design of Multioutput Sampling Schedules - Software and Applications to Endocrine - Metabolic and Pharmacokinetic Models
C Cobelli, A Ruggeri, JJ Distefano, EM Landaw
IEEE Transactions on Biomedical Engineering 1985
Identification of Endocrine-Metabolic and Pharmacokinetic Systems
C Cobelli
IFAC Proceedings Volumes 1985
Continuous infusion of glucose with model assessment: measurement of insulin resistance and ?-cell function in man
JP Hosker, DR Matthews, AS Rudenski, MA Burnett, P Darling, EG Bown, RC Turner
Diabetologia 1985
Mathematics in Biology and Medicine
V Capasso, E Grosso, SL Paveri-Fontana
1985
The metabolic clearance of glucose: measurement and meaning
J Radziuk, HL Lickley
Diabetologia 1985
Modeling and identification of endocrine-metabolic systems. theoretical aspects and their importance in practice
C Cobelli
Mathematical Biosciences 1984
Optimal Experiment Design in Clinical Medicine: A Computer Program and Applications to Compartmental Models
C Cobelli, JJ DiStefano, A Ruggeri
Proceedings of the Annual Symposium on Computer Application in Medical Care 1984
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The American Journal of Digestive Diseases 1949
The intravenous route to blood glucose control
RS Parker, FJ Doyle, NA Peppas
IEEE Engineering in Medicine and Biology Magazine
A model-based algorithm for blood glucose control in Type I diabetic patients
RS Parker, FJ Doyle, NA Peppas
IEEE Transactions on Biomedical Engineering
The effect of physical exercise on the dynamics of glucose and insulin
M Derouich, A Boutayeb
Journal of Biomechanics 2002
The Finland–United States Investigation of Non–Insulin‐Dependent Diabetes Mellitus Genetics (FUSION) Study. II. An Autosomal Genome Scan for Diabetes‐Related Quantitative‐Trait Loci
RM Watanabe, S Ghosh, CD Langefeld, TT Valle, ER Hauser, VL Magnuson, KL Mohlke, K Silander, DS Ally, P Chines, J Blaschak‐Harvan, JA Douglas, WL Duren, MP Epstein, TE Fingerlin, HS Kaleta, EM Lange, C Li, RC McEachin, HM Stringham, E Trager, PP White, J Balow, G Birznieks, J Chang, W Eldridge, MR Erdos, ZE Karanjawala, JI Knapp, K Kudelko, C Martin, A Morales‐Mena, A Musick, T Musick, C Pfahl, R Porter, JB Rayman, D Rha, L Segal, S Shapiro, R Sharaf, B Shurtleff, A So, J Tannenbaum, C Te, J Tovar, A Unni, C Welch, R Whiten, A Witt, K Kohtamaki, C Ehnholm, J Eriksson, L Toivanen, G Vidgren, SJ Nylund, E Tuomilehto‐Wolf, EH Ross, E Demirchyan, WA Hagopian, TA Buchanan, J Tuomilehto, RN Bergman, FS Collins, M Boehnke
The American Journal of Human Genetics 2000
Insulin secretion, glucose production, and insulin sensitivity in underweight and normal-weight volunteers, and in underweight and normal-weight cancer patients: A Clinical Research Center Study
JA Tayek, S Manglik, E Abemayor
Metabolism 1997
Insulin sensitivity, insulin secretion, and glucose effectiveness in obese subjects: A minimal model analysis
A Taniguchi, Y Nakai, K Doi, H Fukuzawa, M Fukushima, H Kawamura, K Tokuyama, M Suzuki, J Fujitani, H Tanaka, I Nagata
Metabolism 1995
Impaired glucose tolerance after endurance exercise is associated with reduced insulin secretion rather than altered insulin sensitivity
RG Pestell, GM Ward, P Galvin, JD Best, FP Alford
Metabolism 1993
β-Cell hypersecretion and not reduced hepatic insulin extraction is the main cause of hyperinsulinemia in obese nondiabetic subjects
A Kautzky-Willer, G Pacini, B Ludvik, G Schernthaner, R Prager
Metabolism 1992
Dynamic Analysis of the Possible Effects of Leptin in Some Metabolic Disorders in Obesity:
A Talaminos, LM Romero
International Journal of Systems Biology and Biomedical Technologies
Medical Management of Diabetes and Heart Disease
M LeWinter
Medical Management of Diabetes and Heart Disease 2002
Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study
M Mueckler
The Lancet 1992
Insulin sensitivity and B-cell responsiveness to glucose during late pregnancy in lean and moderately obese women with normal glucose tolerance or mild gestational diabetes
TA Buchanan, BE Metzger, N Freinkel, RN Bergman
American Journal of Obstetrics and Gynecology 1990
Age and glucose tolerance in healthy subjects
F Beccaro, G Pacini, A Valerio, R Nosadini, G Crepaldi
Aging clinical and experimental research 1990
An integrated mathematical model of the dynamics of blood glucose and its hormonal control
C Cobelli, G Federspil, G Pacini, A Salvan, C Scandellari
Mathematical Biosciences 1982
A reduced sampling schedule for estimating the parameters of the glucose minimal model from a labeled IVGTT
C Cobelli, A Ruggeri
IEEE Transactions on Biomedical Engineering
A semiclosed-loop algorithm for the control of blood glucose levels in diabetics
ME Fisher
IEEE Transactions on Biomedical Engineering
A semiclosed-loop optimal control system for blood glucose level in diabetics
MS Ibbini, MA Masadeh, MM Amer
Journal of Medical Engineering & Technology 2004
A new glucose-clamp algorithm-theoretical considerations and computer simulations
P Palazzo, V Viti
IEEE Transactions on Biomedical Engineering 1990
Insulin sensitivity and beta-cell responsivity are not decreased in elderly subjects with normal OGTT
G Pacini, A Valerio, F Beccaro, R Nosadini, C Cobelli, G Crepaldi
Journal of the American Geriatrics Society 1988
Evaluation of insulin release and relative peripheral resistance with use of the oral glucose tolerance test: a study in subjects with normoglycaemia, glucose intolerance and non-insulin-dependent diabetes mellitus
J Cederholm, L Wibell
Scandinavian Journal of Clinical & Laboratory Investigation 1985
Objective Medical Decision-making; Systems Approach in Acute Disease: Eindhoven, The Netherlands, 19–22 April 1983 Proceedings
JE Beneken, SM Lavelle
1983
Objective Medical Decision-making; Systems Approach in Acute Disease
JE Beneken, SM Lavelle
1983
Minimal models of glucose/insulin dynamics in the intact organism: A novel approach for evaluation of factors controlling glucose tolerance
RN Bergman, C Cobellit, G Toffolo
T I MEAS CONTROL 1981
A hardware acceleration based on high-level synthesis approach for glucose-insulin analysis
NA Daud, F Mahmud, MH Jabbar
Super twisting sliding mode control algorithm for developing artificial pancreas in type 1 diabetes patients
S Ahmad, NasimUllah, N Ahmed, M Ilyas, W Khan
Biomedical Signal Processing and Control 2017
Real-Time Model-Based Fault Detection of Continuous Glucose Sensor Measurements
K Turksoy, A Roy, A Cinar
IEEE transactions on bio-medical engineering 2017
High gain observer design for blood glucose in type I diabetics
S Bououden
2016
Relationship between insulin sensitivity and in vivo mitochondrial function in skeletal muscle
B Sirikul, BA Gower, GR Hunter, DE Larson-Meyer, BR Newcomer
American journal of physiology. Endocrinology and metabolism 2006
Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: Further evidence for an etiologic association
G Pagano
Hepatology 2002
Optimal Sampling Schedule Design May Reveal Inadequacy of Model Structure: a Case Study on the Minimal Model of Glucose Disappearance
A Ruggeri, C Cobelli
IFAC Proceedings Volumes 1988

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