Jacques A. Durr, … , Barbara Stamoutsos, Marshall D. Lindheimer
Citation Information: J Clin Invest. 1981;68(2):337-346. https://doi.org/10.1172/JCI110261.
Jacques A. Durr, … , Barbara Stamoutsos, Marshall D. Lindheimer
Published August 1, 1981
Citation Information: J Clin Invest. 1981;68(2):337-346. https://doi.org/10.1172/JCI110261.
Abstract
Osmoregulation was studied in near term and age-matched Sprague-Dawley rats. Basal plasma osmolality (Posm) and plasma sodium (PNa) were 281±3 mosmol/kg and 134±3 meq/liter, respectively, on the 20th gestational day compared with 292±3 mosmol/kg and 140±1 meq/liter in virgin animals (P < 0.001), whereas Purea and plasma water content were similar in pregnant and control rats. These differences could not be reproduced in animals receiving progesterone, estrone, or a combination of progesterone and estradiol for 2 wk.
Authors
Jacques A. Durr, Barbara Stamoutsos, Marshall D. Lindheimer
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