Beginning on day 4 ex ovo, and every 3 d thereafter, genetically dystrophic Line 413 chickens were given intraperitoneal injections (4 mg/kg body wt) of a protease inhibitor, leupeptin, pepstatin, or antipain. Experimental chickens received protease inhibitors dissolved in a water:ethanol:dimethyl sulfoxide solution (50:40:10, vol:vol:vol). Control untreated animals received diluent injections.
Michael S. Hudecki, Catherine M. Pollina, Reid R. Heffner
Title and authors | Publication | Year |
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Annual Reports in Medicinal Chemistry
JJ Liu, TW Lee |
Annual Reports in Medicinal Chemistry Volume 46 | 2011 |
Increased resistance of the collagen in avian dystrophic muscle to collagenolytic attack: Evidence for increased crosslinking
H Feit, M Kawai, AS Mostafapour |
Muscle & Nerve | 1989 |
Oxidative stress and muscular dystrophy
ME Murphy, JP Kehrer |
Chemico-Biological Interactions | 1989 |
High molecular weight kininogen, the extracellular inhibitor of thiol proteases, is deficient in hamsters with muscular dystrophy
RW Colman, HN Bradford, AH Warner |
Thrombosis Research | 1989 |
Abnormal response to calmodulin in vitro of dystrophic chicken muscle membrane calcium-ATPase activity
J Galindo, MS Hudecki, FB Davis, PJ Davis, HR Thacore, CM Pollina, SD Blas, M Schoenl |
Biochemistry | 1988 |
Slow-type C-protein in dystrophic chicken fast pectoralis muscle
T Obinata, K Shinbo |
Muscle & Nerve | 1987 |
Abnormal expression of the calmodulin gene in muscle from the dystrophic chicken
MS Hudecki, PK Kibler, CM Pollina, HR Thacore, PJ Davis, FB Davis |
Biochemical and Biophysical Research Communications | 1986 |
Effects of percutaneous electrical stimulation on functional ability, plasma creatine kinase, and pectoralis musculature of normal and genetically dystrophic chickens
MS Hudecki, AT Caffiero, CC Gregorio, CM Pollina |
Experimental Neurology | 1985 |
Physiological and Biochemical Characterization of Avian Dystrophic Muscle Reveals Alterations of Collagen
H Feit, M Kawai |
Annals of the New York Academy of Sciences | 1985 |
Stiffness and contractile properties of avian normal and dystrophic muscle bundles as measured by sinusoidal length perturbations
H Feit, M Kawai, MI Schulman |
Muscle & Nerve | 1985 |
Characterization of Lymphocyte Interferons with Different Species Specificities From Normal and Genetically Dystrophic Chickens
HR Thacore, PK Kibler, CC Gregorio, CM Pollina, MS Hudecki |
Journal of Interferon Research | 1985 |
In vivo effects of three calcium blockers on chickens with inherited muscular dystrophy
MS Hudecki, CM Pollina, RR Heffner |
Experimental Neurology | 1984 |
Drugs in muscular dystrophy of the chicken: Corticosterone -21-acetate
RK Entrikin, GT Patterson, BW Wilson |
Muscle & Nerve | 1984 |
31P-NMR studies of normal and dystrophic chicken muscle
J Pettegrew, N Minshew, H Feit |
Muscle & Nerve | 1984 |
Changes in Turbidity During Microtubule Assembly in Brain Extracts from Normal Chickens and Chickens with Muscular Dystrophy
H Feit, R Domke |
Journal of Neurogenetics | 1984 |
Immunocytochemical studies of cathepsin D in human skeletal muscle
JN Whitaker, TE Bertorini, JR Mendell |
Annals of Neurology | 1983 |
Limited benefit to genetically dystrophic chickens from a synthetic proteinase inhibitor: Ep475
MS Hudecki, CM Pollina, RR Heffner |
Journal of the Neurological Sciences | 1983 |
Paradoxical effect of leupeptin in vivo on Cathepsin B activity
JH Sutherland, LM Greenbaum |
Biochemical and Biophysical Research Communications | 1983 |
Tissue and subcellular distribution of enzymes inactivating leupeptin
CP Brown, RJ Beynon |
Bioscience Reports | 1983 |
Parenteral branched-chain amino acid treatment and avian dystrophy
MS Hudecki, CM Pollina, RR Heffner |
Muscle & Nerve | 1982 |
The chicken dystrophic model: Does hypersensitivity to glucocorticoids cause atrophy?
DC DuBois, RR Almon |
Experimental Neurology | 1982 |
In vivo administration of a thiol protease inhibitor, E-64-C, to hereditary dystrophic chicken
H Sugita, M Kimura, Y Tarumoto, M Tamai, K Hanada, S Ishiura, I Nonaka, M Ohzeki, K Imahori |
Muscle & Nerve | 1982 |
Fragmentation analysis of normal and dystrophic avian muscle
H Feit, M Stauver, R Domke, JW Shay |
Muscle & Nerve | 1982 |
Persistence of the expression of β-tropomyosin in dystrophic avian pectoral muscle
H Feit, R Domke |
Cell Motility | 1982 |
Therapeutic trial with protease inhibitor (Leupeptin) in chicken muscular dystrophy: A histologic and histochemical study
I Nonaka, S Ishiura, A Takagi, H Sugita |
Acta Neuropathologica | 1982 |