Differences in the growth hormone (GH) responses to primary and to secondary stimulation with triiodothyronine (T3) were studied in rats deprived of thyroid hormone from birth. Neonatal hypothyroidism was induced in pups by feeding pregnant rats an iodine-deficient, propylthiouracil-containing diet. T3 stimulation was carried out in pups by subcutaneous injection of a single dose of 50 μg T3/100 g body wt. Pituitary GH content, rate of GH synthesis in vitro, and GH messenger (m)RNA activity in a cellfree translation system were measured.
Hisao Seo, Caryn Wunderlich, Gilbert Vassart, Samuel Refetoff
Title and authors | Publication | Year |
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Association of maternal TSH and neonatal metabolism: A large prospective cohort study in China.
Hou Q, Zou H, Zhang S, Lin J, Nie W, Cui Y, Liu S, Han J |
Frontiers in Endocrinology | 2022 |
Hypothyroid offspring replacement with euthyroid wet nurses during lactation improves thyroid programming without modifying metabolic programming
J Tapia-Martínez, M Franco-Colín, R Ortiz-Butron, M Pineda-Reynoso, E Cano-Europa |
Archives of Endocrinology and Metabolism | 2019 |
Hypothyroid offspring replacement with euthyroid wet nurses during lactation improves thyroid programming without modifying metabolic programming.
Tapia-Martínez J, Franco-Colín M, Ortiz-Butron R, Pineda-Reynoso M, Cano-Europa E |
Archives of Endocrinology and Metabolism | 2019 |
American Thyroid Association Guide to Investigating Thyroid Hormone Economy and Action in Rodent and Cell Models
AC Bianco, G Anderson, D Forrest, VA Dr, B Gereben, BW Kim, PA Kopp, XH Liao, MJ Obregon, R Peeters, S Refetoff, D Sharlin, WS Simonides, RE Weiss, G Williams |
Thyroid | 2013 |
International Review of Cytology
RA Miller |
International Review of Cytology | 1991 |
Processing of the Primary Transcript for the Rat Growth Hormone GeneIn Vivo
DG Gardner, G Cathala, NY Lan, Y David-Inouye, JD Baxter |
DNA | 1988 |
Processing of the Primary Transcript for the Rat Growth Hormone Gene In Vivo
DG Gardner, G Cathala, NY Lan, Y David-Inouye, JD Baxter |
DNA | 1988 |
Hereditary pituitary dwarfism in mice affects skeletal and cardiac myosin isozyme transitions differently
RG Whalen, M Toutant, GS Butler-Browne, SC Watkins |
The Journal of Cell Biology | 1985 |
Effects of hypothyroidism on myosin isozyme transitions in developing rat muscle
GS Butler-Browne, D Herlicoviez, RG Whalen |
FEBS Letters | 1984 |
Regulation of myosin isoenzyme composition in fetal and neonatal rat ventricle by endogenous thyroid hormones
RA Chizzonite, R Zak |
The Journal of biological chemistry | 1984 |
Change in synthesis rates of alpha- and beta-myosin heavy chains in rabbit heart after treatment with thyroid hormone
AW Everett, WA Clark, RA Chizzonite, R Zak |
The Journal of biological chemistry | 1983 |