Citations to this article

Cell Surface Differentiation Antigens of the Malignant T Cell in Sezary Syndrome and Mycosis Fungoides
Barton F. Haynes, … , John Minna, Anthony S. Fauci
Barton F. Haynes, … , John Minna, Anthony S. Fauci
Published February 1, 1981
Citation Information: J Clin Invest. 1981;67(2):523-530. https://doi.org/10.1172/JCI110062.
View: Text | PDF
Research Article Article has an altmetric score of 3

Cell Surface Differentiation Antigens of the Malignant T Cell in Sezary Syndrome and Mycosis Fungoides

Abstract

Using a panel of monoclonal antibodies and rabbit heteroantisera, we have studied the cell surface markers of peripheral blood (PB) Sezary cells from six patients with mycosis fungoides or Sezary syndrome, disease grouped within the spectrum of cutaneous T cell lymphomas (CTCL). Furthermore, we have studied two cell lines (Hut 78 and Hut 102) derived from malignant Sezary T cells from CTCL patients. The monoclonal antibody 3A1 defines a major human PB T cell subset (85% of PB T cells) while the antigen defined by the monoclonal antibody 4F2 is present on a subset (70%) of activated PB T cells and on circulating PB monocytes.

Authors

Barton F. Haynes, Paul Bunn, Dean Mann, Charles Thomas, George S. Eisenbarth, John Minna, Anthony S. Fauci

×

Total citations by year

Year: 2020 2018 2017 2012 2011 2010 2009 2008 2007 2004 2003 2002 2001 1999 1996 1992 1990 1989 1988 1986 1985 1984 1983 1981 Total
Citations: 1 1 1 2 1 1 1 1 1 1 3 3 2 2 3 2 2 1 2 8 6 7 3 2 57
Citation information

Citations to this article (57)

Title and authors Publication Year
It is time to adopt a multicolor immunophenotyping approach to evaluate blood for Sézary syndrome and mycosis fungoides
FE Craig 		Cytometry. Part B, Clinical cytometry 2020
The clinical importance of CD4 + CD7 − in human diseases: HAFTCHESHMEH et al
SM Haftcheshmeh, A Tajbakhsh, M Kazemi, SA Esmaeili, F Mardani, M Fazeli, A Sahebkar 		Journal of Cellular Physiology 2018
CD4 + CD26 − lymphocytes are useful to assess blood involvement and define B ratings in cutaneous T cell lymphoma
EC Vonderheid, JS Hou 		Leukemia & Lymphoma 2017
The histone deacetylase inhibitor, romidepsin, suppresses cellular immune functions of cutaneous T-cell lymphoma patients
MJ Kelly-Sell, YH Kim, S Straus, B Benoit, C Harrison, K Sutherland, R Armstrong, WK Weng, LC Showe, M Wysocka, AH Rook 		American Journal of Hematology 2012
CD98 at the crossroads of adaptive immunity and cancer
J M., MH Ginsberg 		Journal of cell science 2012
Synergistic Enhancement of Cellular Immune Responses by the Novel Toll Receptor 7/8 Agonist 3M 007 and Interferon-γ: Implications for Therapy of Cutaneous T-Cell Lymphoma
M Wysocka, N Dawany, B Benoit, AV Kossenkov, AB Troxel, JM Gelfand, M Kelly-Sell, LC Showe, AH Rook 		Leukemia & Lymphoma 2011
Lessons Learned From the Systematic Evaluation of Cutaneous T-Cell Lymphomas at the National Cancer Institute and the Roadmap for Future Studies
PA ., T Pacheco 		Clinical Lymphoma, Myeloma & Leukemia 2010
Chronic T cell lymphocytosis with large granular lymphocytes of helper (OKT4) phennoype
A Berrebi, M Talmor, EJ Vorst, M Shtalrid, A Polliack, E Nir 		Scandinavian Journal of Haematology 2009
Arrestin 3 Mediates Endocytosis of CCR7 following Ligation of CCL19 but Not CCL21
MA Byers, PA Calloway, L Shannon, HD Cunningham, S Smith, F Li, BC Fassold, CM Vines 		Journal of immunology (Baltimore, Md. : 1950) 2008
Synthetic Imidazoquinolines Potently and Broadly Activate the Cellular Immune Response of Patients with Cutaneous T-Cell Lymphoma: Synergy with Interferon-γ Enhances Production of Interleukin-12
M Wysocka, S Newton, BM Benoit, C Introcaso, AS Hancock, J Chehimi, SK Richardson, JM Gelfand, LJ Montaner, AH Rook 		Clinical Lymphoma & Myeloma 2007
Enhancement of the host immune responses in cutaneous T-cell lymphoma by CpG oligodeoxynucleotides and IL-15
M Wysocka, BM Benoit, S Newton, L Azzoni, LJ Montaner, AH Rook 		Blood 2004
The relevance of peripheral blood T-helper 1 and 2 cytokine pattern in the evaluation of patients with mycosis fungoides and Sezary syndrome
E Papadavid, J Economidou, A Psarra, V Kapsimali, V Mantzana, C Antoniou, K Limas, A Stratigos, N Stavrianeas, G Avgerinou, A Katsambas 		British Journal of Dermatology 2003
The Sézary syndrome: hematologic criteria
EC Vonderheid, MG Bernengo 		Hematology/Oncology Clinics of North America 2003
Treatment of cutaneous T cell lymphoma with extracorporeal photopheresis induces Fas-ligand expression on treated T cells, but does not suppress the expression of co-stimulatory molecules on monocytes
J Bladon, PC Taylor 		Journal of Photochemistry and Photobiology B Biology 2003
Synergistic Enhancement of Cell-Mediated Immunity by Interleukin-12 Plus Interleukin-2: Basis for Therapy of Cutaneous T Cell Lymphoma
MH Zaki, M Wysocka, SE Everetts, KS Wang, LE French, J Ritz, AH Rook 		Journal of Investigative Dermatology 2002
Effect of insulin-dependent diabetes mellitus on response to extracorporeal photopheresis in patients with Sézary syndrome
SA Bouwhuis, RA el-Azhary, LE Gibson, MT McEvoy, MR Pittelkow 		Journal of the American Academy of Dermatology 2002
Sézary syndrome patients demonstrate a defect in dendritic cell populations: effects of CD40 ligand and treatment with GM-CSF on dendritic cell numbers and the production of cytokines
M Wysocka, MH Zaki, LE French, J Chehimi, M Shapiro, SE Everetts, KS McGinnis, L Montaner, AH Rook 		Blood 2002
Dysregulation of Lymphocyte Interleukin-12 Receptor Expression in Sezary Syndrome
MH Zaki, RB Shane, Y Geng, LC Showe, SE Everetts, DH Presky, M Wysocka, JS Moore, AH Rook 		Journal of Investigative Dermatology 2001
Variable CD7 Expression on T Cells in the Leukemic Phase of Cutaneous T Cell Lymphoma (Sézary Syndrome)
EC Vonderheid, RD Bigler, A Kotecha, CM Boselli, SR Lessin, MG Bernengo, M Polansky 		Journal of Investigative Dermatology 2001
Dysregulated synthesis of intracellular type 1 and type 2 cytokines by T cells of patients with cutaneous T-cell lymphoma
BN Lee, M Duvic, CK Tang, C Bueso-Ramos, Z Estrov, JM Reuben 		Clinical and diagnostic laboratory immunology 1999
Sézary T-Cell Activating Factor Is a Chlamydia pneumoniae -Associated Protein
JT Abrams, EC Vonderheid, S Kolbe, DM Appelt, EJ Arking, BJ Balin 		Clinical and diagnostic laboratory immunology 1999
T-Cell lymphoma cell lines (HUT102 and HUT78) established at the National Cancer Institute: History and importance to understanding the biology, clinical features, and therapy of cutaneous T-cell lymphomas (CTCL) and adult T-cell leukemia-lymphomas (ATLL)
PA Bunn, FM Foss 		Journal of Cellular Biochemistry 1996
The Potential Therapeutic Role of Interleukin-12 in Cutaneous T-Cell Lymphoma
AH Rook, M Rubin, FE Fox, Z Niu, M Cassin, BR Vowels, SL Gottleib, EC Vonderheid, SR Lessin, G Trinchierf 		Annals of the New York Academy of Sciences 1996
Detection of circulating T cells with CD4+CD7− immunophenotype in patients with benign and malignant lymphoproliferative dermatoses
CB Harmon, TE Witzig, JA Katzmann, MR Pittelkow 		Journal of the American Academy of Dermatology 1996
Aberrant Cytokine Production By Sezary Syndrome Patients: Cytokine Secretion Pattern Resembles Murine Th2 Cells
BR Vowels, M Cassin, EC Vonderheid, AH Rook 		Journal of Investigative Dermatology 1992
CD7– T cells in rheumatoid arthritis
AI Lazarovits, MJ White, J Karsh 		Arthritis & Rheumatism 1992
Induction of antigen expression of follicular dendritic cells in a monoblastic cell line. A contribution to its cellular origin
A Fliedner, MR Parwaresch, AC Feller 		The Journal of Pathology 1990
Hodgkin's disease presenting in the skin: Case report and review of the literature
TG Hayes, VR Rabin, T Rosen, MA Zubler 		Journal of the American Academy of Dermatology 1990
Laboratory and clinical applications of monoclonal antibodies for leukemias and non-Hodkin's lymphoma
KA Foon 		Current Problems in Cancer 1989
Epidermal Interleukin-1 is Increased in Cutaneous T-Cell Lymphoma
VA Tron, D Rosenthal, DN Sauder 		Journal of Investigative Dermatology 1988
Lymphoma-specific T- and B-cell responses suggest the involvement of HTLV-I in virus-non-productive lymphomas of a married couple
EM Schneider, JG Saal, DL Mann, G Pawelec, J Schneider, W Schlote, P Wernet 		International Journal of Cancer 1988
Immunoregulatory function and expression of OKT17 antigen of adult T-cell leukemia cells
H Okawa, K Takase, S Takagi, J Yata, M Matsumoto, T Matsumoto 		Cancer 1986
Allergic Contact Dermatitis: Novel Immunohistologic Features
GS Wood, AS Volterra, EA Abel, BJ Nickoloff, RM Adams 		Journal of Investigative Dermatology 1986
The human T-cell leukemias: Clinical, cytomorphologic, immunophenotypic, and genotypic characteristics
DM Knowles 		Human Pathology 1986
Immunobiology of the expanded T cells in T-cell leukemia and T-gamma lymphocytosis
F Miedema, CJ Melief 		Leukemia Research 1986
Leu-8 and Leu-9 antigen phenotypes: Immunologic criteria for the distinction of mycosis fungoides from cutaneous inflammation
GS Wood, EA Abel, RT Hoppe, RA Warnke 		Journal of the American Academy of Dermatology 1986
Review: Class II molecules of the major histocompatibility complex considered as differentiation markers
SF Radka, DJ Charron, FM Brodsky 		Human Immunology 1986
Expression of E10 antigen on functionally distinct human T-cell subpopulations: Comparison with 3A1 defined subsets
Y Richard, E Georget 		Cellular Immunology 1986
Natural and concanavalin A-induced cytotoxic activity towards continuously growing B lymphocytes derived from patients with cutaneous T-cell lymphoma
JR Jensen, K Kaltoft, S Bisballe, K Thestrup-Pedersen 		Archives of Dermatological Research 1986
Functional and phenotypic studies of Japanese adult T cell leukemia cells
C Morimoto, T Matsuyama, C Oshige, H Tanaka, T Hercend, EL Reinherz, SF Schlossman 		Journal of Clinical Investigation 1985
Analysis of helper activity on pokeweed mitogen- and interleukin 2-driven immunoglobulin synthesis by neoplastic T4+ cells
F Miedema, JW van Oostveen, FG Terpstra, AW van Bake, R Willemze, EA Rauws, R Bieger, MB van Veer, D Catovsky, CJ Melief 		Journal of Clinical Investigation 1985
Sézary syndrome: phenotypic and functional characterization of the neoplastic cells
E Ralfkiaer, GL Wantzin, JK Larsen, V Andersen, C Geisler, T Plesner, K Thomsen 		Scandinavian Journal of Haematology 1985
Hand-mirror variant of acute lymphoblastic leukemia. Evidence for early T-cell lineage in two cases by evaluation with monoclonal antibodies
M Gramatzki, DM Strong, B Duval-Arnould, G Morstyn, HR Schumacher 		Cancer 1985
T gamma lymphocytosis is clinically non-progressive but immunologically heterogeneous
F Miedema, FG Terpstra, JW Smit, JP van der Veen, CJ Melief 		Clinical & Experimental Immunology 1985
Characterization of cell lines enhancing IL-2 production by human phytohemagglutinin-stimulated lymphocytes
M Gramatzki, GD Bonnard, RB Herberman, DM Strong 		Cellular Immunology 1985
Early diagnosis of cutaneous T-cell lymphoma by DNA flow cytometry on skin biopsies
GL Wantzin, JR Larsen, IJ Christensen, E Ralfkiær, K Thomsen 		Cancer 1984
Human T-cell leukaemia virus (HTLV) in the United Kingdom
MF Greaves, W Verbi, R Tilley, TA Lister, J Habeshaw, HG Guo, CD Trainor, M Robert-Guroff, W Blattner, M Reitz, RC Gallo 		International Journal of Cancer 1984
Immunopathology of non-Hodgkin lymphomas
H Huber, C Gattringer, W Knapp, H Stein 		Klinische Wochenschrift 1984
Regulatory activity of neoplastic T cells in Sezary syndrome on in vitro immunoglobulin production
F Miedema, R Willemze, FG Terpstra, WA van Vloten, CJ Meijer, CJ Melief 		Leukemia Research 1984
Immunopathology of non-Hodgkin lymphomas
H Huber, C Gattringer, W Knapp, H Stein 		Klinische Wochenschrift 1984
Adult T-cell lymphoma/leukemia in a Caribbean patient: Cytogenetic, immunologic, and ultrastructural findings
V Brito-Babapulle, E Matutes, U Hegde, D Catovsky 		Cancer Genetics and Cytogenetics 1984
Peripheral T Cell Lymphoma in Adults: Morphological and Phenotypical Study of Four Cases
LP Ruco, A Stoppacciaro, M Mirolo, M Valtieri, D Vitolo, S Uccini, AP Anselmo, C Guglielmi, F Mandelli, CD Baroni 		TUMORI 1984
Lymphocyte phenotype and function in pseudolymphoma associated with Sjögren's syndrome
RI Fox, TC 3rd, S Fong, CA Robinson, EL Morgan, JA Robb, FV Howell 		Journal of Clinical Investigation 1983
An OKT4+ T-Cell Population with Suppressor Activity in Sezary Syndrome
C Farnarier-Seidel, S Kaplanski, MM Golstein, E Jancovici, J Sayag, R Depieds 		Scandinavian Journal of Immunology 1983
Candidate counterparts of sezary cells and adult T-cell lymphoma-leukaemia cells in normal peripheral blood: An ultrastructural study with the immunogold method and monoclonal antibodies
E Matutes, D Robinson, M O'Brien, BF Haynes, H Zola, D Catovsky 		Leukemia Research 1983
Human T Lymphocyte Antigens as Defined by Monoclonal Antibodies
BF Haynes 		Immunological Reviews 1981
Phenotypic Characterization of Cutaneous T-Cell Lymphoma: Use of Monoclonal Antibodies to Compare with Other Malignant T Cells
BF Haynes, RS Metzgar, JD Minna, PA Bunn 		New England Journal of Medicine 1981

Advertisement