JCI - Citations to Lipoxygenation of arachidonic acid as a source of polymorphonuclear leukocyte chemotactic factors in synovial fluid and tissue in rheumatoid arthritis and spondyloarthritis.

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Lipoxygenation of arachidonic acid as a source of polymorphonuclear leukocyte chemotactic factors in synovial fluid and tissue in rheumatoid arthritis and spondyloarthritis.

L B Klickstein, … , C Shapleigh, E J Goetzl

L B Klickstein, … , C Shapleigh, E J Goetzl

Published November 1, 1980
Citation Information: J Clin Invest. 1980;66(5):1166-1170. https://doi.org/10.1172/JCI109947.

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Differential Metabolome in Rheumatoid Arthritis: a Brief Perspective P Agnihotri, Monu, S Ramani, D Chakraborty, M Saquib, S Biswas	Current Rheumatology Reports	2021
Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules: The Shape of Organic Synthesis to Come Y Kobayashi		2019
LOX inhibitor HOEC interfered arachidonic acid metabolic flux in collagen-induced arthritis rats Wen Yang, Xia Wang, Liuxin Xu, Honglin Li, Rui Wang	American journal of translational research	2018
Biosynthesis of leukotriene B 4 M Wan, X Tang, A Stsiapanava, JZ Haeggström	Seminars in Immunology	2017
Reduction of GPSM3 expression akin to the arthritis-protective SNP rs204989 differentially affects migration in a neutrophil model BJ Gall, AB Schroer, JD Gross, V Setola, DP Siderovski	Genes and Immunity	2016
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Targeting leukotriene B 4 in inflammation AD Gennaro, JZ Haeggström	Expert Opinion on Therapeutic Targets	2014
The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes N Cloutier, S Tan, LH Boudreau, C Cramb, R Subbaiah, L Lahey, A Albert, R Shnayder, R Gobezie, PA Nigrovic, RW Farndale, WH Robinson, A Brisson, DM Lee, E Boilard	EMBO Molecular Medicine	2012
5-Lipoxygenase Metabolic Contributions to NSAID-Induced Organ Toxicity BP Burnett, RM Levy	Advances in Therapy	2012
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Lipid-cytokine-chemokine cascades orchestrate leukocyte recruitment in inflammation CD Sadik, AD Luster	Journal of leukocyte biology	2011
Arthritis K Huang, C Zhang, X Zhang, L Wu, L Shen, Q Guo	Arthritis	2011
The Enzymes EJ Chenette, CJ Der	Protein Prenylation PART A	2011
Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease JZ Haeggström, CD Funk	Chemical Reviews	2011
Annual Reports in Medicinal Chemistry JJ Liu, TW Lee	Annual Reports in Medicinal Chemistry Volume 46	2011
Joint Tissues Amplify Inflammation and Alter Their Invasive Behavior via Leukotriene B 4 in Experimental Inflammatory Arthritis M Chen, BK Lam, AD Luster, S Zarini, RC Murphy, AM Bair, RJ Soberman, DM Lee	Journal of immunology (Baltimore, Md. : 1950)	2010
Discovery of novel leukotriene A4 hydrolase inhibitors based on piperidine and piperazine scaffolds V Sandanayaka, B Mamat, N Bhagat, L Bedell, G Halldorsdottir, H Sigthorsdottir, Þ Andrésson, A Kiselyov, M Gurney, J Singh	Bioorganic & Medicinal Chemistry Letters	2010
Pulmonary surfactant: an immunological perspective ZC Chroneos, Z Sever-Chroneos, VL Shepherd	Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology	2009
A distinctive role of the leukotriene B4 receptor BLT1 in osteoclastic activity during bone loss H Hikiji, S Ishii, T Yokomizo, T Takato, T Shimizu	Proceedings of the National Academy of Sciences	2009
Expression and activity of COX-1 and 2 and 5-LOX in joint tissues from dogs with naturally occurring coxofemoral joint osteoarthritis BD Lascelles, S King, S Roe, DJ Marcellin-Little, S Jones	Journal of Orthopaedic Research	2009
Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids KR Gheorghe, M Korotkova, AI Catrina, L Backman, E Klint, HE Claesson, O Rådmark, PJ Jakobsson	Arthritis Research & Therapy	2009
Synthesis and biological evaluation of N-mercaptoacylcysteine derivatives as leukotriene A4 hydrolase inhibitors H Enomoto, Y Morikawa, Y Miyake, F Tsuji, M Mizuchi, H Suhara, K Fujimura, M Horiuchi, M Ban	Bioorganic & Medicinal Chemistry Letters	2009
Neutrophil activation induced by ArtinM: Release of inflammatory mediators and enhancement of effector functions KA Toledo, C Scwartz, AF Oliveira, MC Conrado, ES Bernardes, LC Fernandes, MC Roque-Barreira, G Pereira-da-Silva, AN Moreno	Immunology Letters	2009
Discovery of 4-[(2 S )-2-{[4-(4-Chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic Acid (DG-051) as a Novel Leukotriene A4 Hydrolase Inhibitor of Leukotriene B4 Biosynthesis V Sandanayaka, B Mamat, RK Mishra, J Winger, M Krohn, LM Zhou, M Keyvan, L Enache, D Sullins, E Onua, J Zhang, G Halldorsdottir, H Sigthorsdottir, A Thorlaksdottir, G Sigthorsson, M Thorsteinnsdottir, DR Davies, LJ Stewart, DE Zembower, T Andresson, AS Kiselyov, J Singh, ME Gurney	Journal of Medicinal Chemistry	2009
The roles of prostanoids, leukotrienes, and platelet-activating factor in bone metabolism and disease H Hikiji, T Takato, T Shimizu, S Ishii	Progress in Lipid Research	2008
Synthesis and biological evaluation of N-mercaptoacylproline and N-mercaptoacylthiazolidine-4-carboxylic acid derivatives as leukotriene A4 hydrolase inhibitors H Enomoto, Y Morikawa, Y Miyake, F Tsuji, M Mizuchi, H Suhara, K Fujimura, M Horiuchi, M Ban	Bioorganic & Medicinal Chemistry Letters	2008
Reduction of cPLA2αoverexpression: An efficient anti-inflammatory therapy for collagen-induced arthritis L Raichel, S Berger, N Hadad, L Kachko, M Karter, I Szaingurten-Solodkin, RO Williams, M Feldmann, R Levy	European Journal of Immunology	2008
Studies in Natural Products Chemistry M Seki	Studies in Natural Products Chemistry	2008
Inhibition of lipoxygenases and cyclooxygenases by linoleyl hydroxamic acid: comparative in vitro studies IA Butovich, SM Lukyanova	Journal of lipid research	2008
5-Lipoxygenase-derived lipid mediators are not required for the development of NSAID-induced inflammatory bowel disease in IL-10 −/− mice S Narushima, D DiMeo, J Tian, J Zhang, D Liu, DJ Berg	AJP Gastrointestinal and Liver Physiology	2008
Food Science and Technology M Vemuri, D Kelley	Fatty Acids in Foods and their Health Implications,Third Edition	2007
Increased interleukin-10 production and Th2 skewing in the absence of 5-lipoxygenase D DiMeo, J Tian, J Zhang, S Narushima, DJ Berg	Immunology	2007
Involvement of LTB 4 in zymosan-induced joint nociception in mice: participation of neutrophils and PGE 2 AT Guerrero, WA Verri, TM Cunha, TA Silva, IR Schivo, D Dal-Secco, C Canetti, FA Rocha, CA Parada, FQ Cunha, SH Ferreira	Journal of leukocyte biology	2007
Clinical trial of a leucotriene B4 receptor antagonist, BIIL 284, in patients with rheumatoid arthritis F Díaz-González, RH Alten, WG Bensen, JP Brown, JT Sibley, M Dougados, S Bombardieri, P Durez, P Ortiz, G de-Miquel, A Staab, R Sigmund, L Salin, C Leledy, SH Polmar	Annals of the rheumatic diseases	2006
Therapeutic options for 5-lipoxygenase inhibitors O Werz, D Steinhilber	Pharmacology & Therapeutics	2006
Targeted disruption of leukotriene B4 receptors BLT1 and BLT2: a critical role for BLT1 in collagen-induced arthritis in mice WH Shao, AD Prete, CB Bock, B Haribabu	Journal of immunology (Baltimore, Md. : 1950)	2006
Neutrophil-derived leukotriene B4 is required for inflammatory arthritis M Chen, BK Lam, Y Kanaoka, PA Nigrovic, LP Audoly, KF Austen, DM Lee	Journal of Experimental Medicine	2006
Bailey's Industrial Oil and Fat Products AB Christophe	Bailey's Industrial Oil and Fat Products	2005
Inflammatory Cytokines Released from the Facet Joint Tissue in Degenerative Lumbar Spinal Disorders A Igarashi, S Kikuchi, S Konno, K Olmarker	Spine	2004
Inhibition of leukotriene B4-induced CD11B/CD18 (Mac-1) expression by BIIL 284, a new long acting LTB4 receptor antagonist, in patients with rheumatoid arthritis R Alten, E Gromnica-Ihle, C Pohl, J Emmerich, J Steffgen, R Roscher, R Sigmund, B Schmolke, G Steinmann	Annals of the rheumatic diseases	2004
Ex-vivo regulation of endotoxin-induced tissue factor in whole blood by eicosanoids KE Eilertsen, JO Olsen, B Østerud	Blood Coagulation & Fibrinolysis	2003
Synthesis of Potent Leukotriene A 4 Hydrolase Inhibitors. Identification of 3-[Methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic Acid TD Penning, MA Russell, BB Chen, HY Chen, CD Liang, MW Mahoney, JW Malecha, JM Miyashiro, SS Yu, LJ Askonas, JK Gierse, EI Harding, MK Highkin, JF Kachur, SH Kim, D Villani-Price, EY Pyla, NS Ghoreishi-Haack, WG Smith	Journal of Medicinal Chemistry	2002
Anti-inflammatory effect of FR140423, a novel selective cyclo-oxygenase-2 inhibitor, in rat adjuvant arthritis without gastrointestinal side effects T Ochi, T Goto	The Journal of pharmacy and pharmacology	2000
Structure−Activity Relationship Studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a Potent Inhibitor of Leukotriene A 4 (LTA 4 ) Hydrolase TD Penning, NS Chandrakumar, BB Chen, HY Chen, BN Desai, SW Djuric, SH Docter, AF Gasiecki, RA Haack, JM Miyashiro, MA Russell, SS Yu, DG Corley, RC Durley, BF Kilpatrick, BL Parnas, LJ Askonas, JK Gierse, EI Harding, MK Highkin, JF Kachur, SH Kim, GG Krivi, D Villani-Price, EY Pyla, WG Smith, NS Ghoreishi-Haack	Journal of Medicinal Chemistry	2000
Chronic Temporomandibular Joint Arthralgia SB Milam	Oral and Maxillofacial Surgery Clinics of North America	2000
Phospholipase A 2 : Its Usefulness in Laboratory Diagnostics E Kaiser	Critical Reviews in Clinical Laboratory Sciences	1999
Synthesis and Structure−Activity Relationships of New 1,3-Disubstituted Cyclohexanes as Structurally Rigid Leukotriene B 4 Receptor Antagonists JM Poudrel, P Hullot, JP Vidal, JP Girard, JC Rossi, A Muller, C Bonne, V Bezuglov, I Serkov, P Renard, B Pfeiffer	Journal of Medicinal Chemistry	1999
The effects of dietary n-3 polyunsaturated fatty acids on neutrophils RI Sperling	Proceedings of the Nutrition Society	1998
Pharmacokinetics and pharmacodynamics of the leukotriene B4 receptor antagonist CP-105,696 in man following single oral administration TE Liston, MJ Conklyn, J Houser, KD Wilner, A Johnson, G Apseloff, C Whitacre, HJ Showell	British Journal of Clinical Pharmacology	1998
Antiinflammatory effect of tepoxalin Blood and synovial tissue studied in patients with knee arthrosis RE Willburger, RH Wittenberg, K Schmidt, KS Kleemeyer, BA Peskar	Acta Orthopaedica	1998
Synthesis of structural analogues of leukotriene B4 and their receptor binding activity M Konno, T Nakae, S Sakuyama, M Nishizaki, Y Odagaki, H Nakai, N Hamanaka	Bioorganic & Medicinal Chemistry	1997
Cytokines in Rheumatoid Arthritis: Localization in Arthritic Joint Tissue and Regulation in vitro BW Deleuran	Scandinavian Journal of Rheumatology	1996
Immune complex induced arthritis in rats: role of lipid mediators on cell infiltration FA Rocha, LE Andrade, S Jancar	Mediators of Inflammation	1996
Inflammatory mediators in equine synovial fluid KT Gibson, H Hodge, T Whittem	Australian Veterinary Journal	1996
Development of In Vitro Biocompatibility Assays for Surgical Material JL Charissoux, A Najid, JC Moreau, D Setton, M Rigaud	Clinical Orthopaedics and Related Research	1996
Synthesis and pharmacological profile of new 1,3-disubstituted cyclohexanes as leukotriene B4 receptor antagonists JM Poudrel, P Hullot, JP Vidal, JP Girard, JC Rossi, A Muller, C Bonne	Bioorganic & Medicinal Chemistry Letters	1996
Leukotriene B4 stimulates osteoclastic bone resorption both in vitro and in vivo C Garcia, BF Boyce, J Gilles, M Dallas, M Qiao, GR Mundy, LF Bonewald	Journal of Bone and Mineral Research	1996
Effect of a Non-Steroidal Anti-Inflammatory Drug on Tissue Levels of Immunoreactive Prostaglandin E<sub>2</sub>, Immunoreactive Leukotriene, and Pain After Periodontal Surgery TP O'Brien, MT Roszkowski, LF Wolff, JE Hinrichs, KM Hargreaves	Journal of Periodontology	1996
Inhibition of eicosanoid release from synovial organ culture by incubation with tepoxalin and its acid metabolite RE Willburger, RH Wittenberg, KS Kleemeyer, R Hoos, FL BrunnerFerber, BA Peskar	Prostaglandins	1996
Overview Pulmonary-Allergy, Dermatological, Gastrointestinal & Arthritis Recent advances in leukotriene B4 receptor antagonist research DJ Fretland, TD Penning	Expert Opinion on Therapeutic Patents	1996
( E )-3-[6-[[(2,6-Dichlorophenyl)thio]methyl]-3-(2-phenylethoxy)-2-pyridinyl]-2- propenoic Acid: A High-Affinity Leukotriene B 4 Receptor Antagonist with Oral Antiinflammatory Activity RA Daines, PA Chambers, JJ Foley, DE Griswold, WD Kingsbury, LD Martin, DB Schmidt, KK Sham, HM Sarau	Journal of Medicinal Chemistry	1996
Leukotriene B4 plays a critical role in the progression of collagen-induced arthritis RJ Griffiths, ER Pettipher, K Koch, CA Farrell, R Breslow, MJ Conklyn, MA Smith, BC Hackman, DJ Wimberly, AJ Milici	Proceedings of the National Academy of Sciences	1995
Leukotriene B4 stimulation of an early elevation of phosphatidic acid mass in human neutrophils J Tou, T Dola	Lipids	1995
Eicosanoids, fatty acids and neutrophils: Their relevance to the pathophysiology of disease EJ Bates	Prostaglandins, Leukotrienes and Essential Fatty Acids	1995
Lipoxygenase products and expression of 5-lipoxygenase and 5-lipoxygenase-activating protein in human cultured synovial cells C Bonnet, P Bertin, J Cook-Moreau, H Chable-Rabinovitch, R Treves, M Rigaud	Prostaglandins	1995
Leukotriene B4 in Bronchoalveolar Lavage Fluid of Patients With Diffuse Panbronchiolitis H Oda, JI Kadota, S Kohno, K Hara	Chest	1995
Omega-3 Fatty Acids and Health JA Nettleton		1995
Airways Smooth Muscle: Neurotransmitters, Amines, Lipid Mediators and Signal Transduction D Raeburn, MA Giembycz		1995
EICOSANOIDS IN RHEUMATOID ARTHRITIS RI Sperling	Rheumatic diseases clinics of North America	1995
Influence of dietary (n-3)-polyunsaturated fatty acids on leukotriene B4 and prostaglandin E2 synthesis and course of experimental tuberculosis in guinea pigs E Mayatepek, K Paul, M Leichsenring, M Pfisterer, D Wagner, M Domann, HJ Bremer, HG Sonntag	Infection	1994
Short Paper: Leukotrien B4-induced lnterleukin-1β in Synovial Cells from Patients with Rheumatoid Arthritis Y Kageyama, Y Koide, S Miyamoto, TO Yoshida, T Inoue	Scandinavian Journal of Rheumatology	1994
Inhibitory effect of allopurinol on adjuvant arthritis in rats M Melli, H Yazici, A Uçar, RK Türker	Agents and Actions	1994
Section Review: Recent progress in the development of leukotriene B4antagonists N Cohen, KA Yagaloff	Expert Opinion on Investigational Drugs	1994
Synthesis of new potent leukotriene B4 antagonists and their biological properties. 2 H Kawakami, N Ohmi, H Nagata	Bioorganic & Medicinal Chemistry Letters	1994
Prostanoids and Leukotrienes in Rheumatoid Synovitis E Moilanen	Pharmacology & Toxicology	1994
5-lipoxygenase: enzyme expression and regulation of activity D Steinhilber	Pharmaceutica Acta Helvetiae	1994
Lipid Mediators JR Vane, RM Botting	Lipid Mediators	1994
Pharmacological profile of a novel, orally active leukotriene B4 antagonist, SM-15178 N Ohmi, C Tani, K Yamada, M Fukui	Inflammation	1994
Afferent and spinal mechanisms of joint pain HG Schaible, BD Grubb	PAIN	1993
Structure/activity relationship of leukotriene B4 and its structural analogues in chemotactic, lysosomal-enzyme release and receptor-binding assays O SOYOMBO, BW SPUR, C SOH, TH LEE	European Journal of Biochemistry	1993
Eicosapentaenoic acid in cystic fibrosis: evidence of a pathogenetic role for leukotriene B4 R Lawrence, T Sorrell	The Lancet	1993
Pathogenesis of rheumatoid arthritis KL Sewell, DE Trentham	The Lancet	1993
Rhythms in the immune system NJ Goulding, ND Hall	Pharmacology & Therapeutics	1993
Inhibitory effect of LY 255283 on the synthesis of leukotriene B(4) and thromboxane A(2) in human peripheral blood polymorphonuclear leukocytes and monocytes M Uğur, M Melli	Mediators of Inflammation	1993
Enhanced levels of leukotriene B(4) in synovial fluid in Lyme disease E Mayatepek, D Hassler, M Maiwald	Mediators of Inflammation	1993
Ebselen is a specific inhibitor of LTB4-mediated migration of human neutrophils RA Patrick, PA Peters, AC Issekutz	Agents and Actions	1993
Inhibition of synovial LTB4 production by a specific leukotriene biosynthesis inhibitor, MK-0591, in a rabbit model of joint inflammation C Brideau, CC Chan, D Guevremont, JH Hutchinson, J McDonnell, V Moore	Drug Development Research	1993
In vitro release of prostaglandins and leukotrienes from synovial tissue, cartilage, and bone in degenerative joint diseases RH Wittenberg, RE Willburger, KS Kleemeyer, BA Peskar	Arthritis & Rheumatism	1993
Leukotriene B4 levels in the arterial blood of patients with chronic obstructive pulmonary disease K Shindo, K Miyakawa, M Fukumura	Current Therapeutic Research	1993
Leukotriene B4 levels in the aqueous humor of patients with diabetic cataract K Shindo, M Tanaka	Current Therapeutic Research	1993
Leukotriene B4 levels in the aqueous humor of patients with senile cataract K Shindo, M Tanaka	Current Therapeutic Research	1993
Enhanced gastric mucosal leukotriene B4 synthesis in patients taking non-steroidal anti-inflammatory drugs N Hudson, M Balsitis, S Everitt, CJ Hawkey	Gut	1993
Decreased polymorphonuclear leucocyte chemotactic response to leukotriene B4 in cystic fibrosis RH Lawrence, TC Sorrell	Clinical & Experimental Immunology	1992
Insoluble immune complex-stimulated neutrophil leukotriene B4 production is dependent on Fc gamma RII and Fc gamma RIII and independent of pertussis toxin-sensitive signal transduction pathways E Crockett-Torabi, CW Smith, JR Kateley, R Patterson, P Tsai, JC Fantone	The American Journal of Pathology	1992
Effect of n-3 and n-6 dietary fats on the lipoxygenase products from stimulated rat neutrophils RA Gibson, MA Neumann, MJ James, JS Hawkes, C Hall, LG Cleland	Prostaglandins, Leukotrienes and Essential Fatty Acids	1992
Fatty Acid Composition of Adipose Tissue and Serum Micronutrients in Relation to Common Rheumatic Complaints in Swedish Adutts 50–70 Years Old L Jacobsson, F Lindgärde, R Manthorpe, B Åkesson	Scandinavian Journal of Rheumatology	1992
ONO-4057, a novel, orally active leukotriene B4 antagonist: Effects on LTB4-induced neutrophil functions K Kishikawa, N Tateishi, T Maruyama, R Seo, M Toda, T Miyamoto	Prostaglandins	1992
Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders KC Srivastava, T Mustafa	Medical Hypotheses	1992
Interleukin-8 in inflammatory rheumatic diseases: synovial fluid levels, relation to rheumatoid factors, production by mononuclear cells, and effects of gold sodium thiomalate and methotrexate M Seitz, B Dewald, M Ceska, N Gerber, M Baggiolini	Rheumatology International	1992
Aktuelle Aspekte der Osteologie TH Ittel, HG Sieberth, HH Matthiaß		1992
Lipoxygenase products in inflammatory synovial fluids and other exudates PB Costello, AN Baer, FA Green	Annals of the rheumatic diseases	1992
Effect of substance P and somatostatin on migration of polymorphonuclear (PMN) cells in vitro G Partsch, M Matucci-Cerinic	Inflammation	1992
Decreased polymorphonuclear leucocyte chemotactic response to leukotriene B4 in cystic fibrosis. Lawrence RH, Sorrelli TC	Clinical & Experimental Immunology	1992
In vivo leukocyte migration in arthritis AK Jones, MA Al-Janabi, K Solanki, R Sobnack, A Greenwood, DV Doyle, KE Britton, EC Huskisson	Arthritis & Rheumatism	1991
Effects of leukotrienes on osteoblastic cell proliferation W Ren, R Dziak	Calcified Tissue International	1991
Leukotriene B4 promotes phospholipid acylation in human neutrophils J Tou, S Healey	Lipids	1991
Muscle protein synthesis in patients with rheumatoid arthritis: effect of chronic corticosteroid therapy on prostaglandin F2αavailability JN Gibson, NL Poyser, WL Morrison, CM Scrimgeour, MJ Rennie	European Journal of Clinical Investigation	1991
Molecular basis of new approaches to the therapy of rheumatoid arthritis D Westmacott, D Bradshaw, MK Kumar, EJ Lewis, EJ Murray, JS Nixon, AD Sedgwick	Molecular Aspects of Medicine	1991
Leukotrienes: their possible role in pulpal and periapical diseases M Torabinejad, E Cotti, G Lessard	Dental Traumatology	1991
Complement C4-derived monocyte-directed chemotaxis-inhibitory factor. A molecular mechanism to cause polymorphonuclear leukocyte-predominant infiltration in rheumatoid arthritis synovial cavities S Matsubara, T Yamamoto, T Tsuruta, K Takagi, T Kambara	The American Journal of Pathology	1991
Accumulation of phosphatidic acid mass and increased de novo synthesis of glycerolipids in platelet-activating-factor-activated human neutrophils J Tou, JR Jeter, CP Dola, S Venkatesh	Biochemical Journal	1991
Rheumatology RA Asherson, R Cervera, DP D'Cruz, GR Hughes	Postgraduate medical journal	1991
Leukotriene B4, interleukin 1 and leucocyte accumulation in titanium and PTFE chambers after implantation in the rat abdominal wall AS Eriksson, P Thomsen	Biomaterials	1991
Neutrophil chemotactic factors in synovial fluids of patients with lyme disease K Georgilis, R Noring, AC Steere, MS Klempner	Arthritis & Rheumatism	1991
Inhibition of Leukotriene Biosynthesis and Polymorphonuclear Leukocyte Functions by Orally Active Quinolylmethoxyphenylamines D Kirstein, MK Thomsen, I Ahnfelt-Renne	Pharmacology & Toxicology	1991
Lipoxygenases and their Products MA Wasserman, EF Smith, DC Underwood, MA Barnette	Lipoxygenases and their Products	1991
Serum Leukotriene B4 Levels in Patients with Obstructive Pulmonary Disease JS Seggev, WH TThornton, TE Edes	Chest	1991
The Role of Leukotriene B4 in Neutrophil Infiltration in Experimentally-induced Inflammation of Rat Tooth Pulp T Okiji, I Morita, I Sunada, S Murota	Journal of dental research	1991
Tolfenamic acid inhibits leukotriene B4-induced chemotaxis of polymorphonuclear leukocytes in vitro H Kankaanranta, E Moilanen, H Vapaatalo	Inflammation	1991
Relationship between leukotriene B4 and immunological parameters in rheumatoid synovial fluids N Ahmadzadeh, M Shingu, M Nobunaga, T Tawara	Inflammation	1991
Cell Motility Factors ID Goldberg		1991
Dietary Omega-3 Fatty Acids: Effects on Lipid Mediators of Inflammation and Rheumatoid Arthritis RI Sperling	Rheumatic diseases clinics of North America	1991
Leukotrienes and inflammation SD Brain, TJ Williams	Pharmacology & Therapeutics	1990
Effect of interleukin 3 on the differentiation and histamine content of cultured bone marrow mast cells HF Chiu, BA Burrall	Agents and Actions	1990
Leukotriene B4 and prostaglandin E2-like activity in synovial fluid in osteoarthritis OS Atik	Prostaglandins, Leukotrienes and Essential Fatty Acids	1990
Effects of N-acetyl-aspartyl glutamic acid and sodium cromoglycate on leukotriene B4secretion by human leukocytes PL Goldschmidt, BV Normand, I Briquet, F Dray	Allergy	1990
Synovitis reduced by inhibition of leukotriene B4: Carragheenan-induced gonarthritis studied in dogs ES Hansen, K Fogh, VE Hjortdal, TB Henriksen, I Noer, H Ewald, T Herlin, K Kragballe, C Bunger	Acta Orthopaedica	1990
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Proliferation of adherent synovial fluid cell cultures is modified by eicosanoids A Andreasen, ES Hansen, K Fogh, K Kragballe, T Herlin	APMIS	1990
Phospholipases in biology and medicine E Kaiser, P Chiba, K Zaky	Clinical Biochemistry	1990
Effects of the nonsteroidal anti-inflammatory compounds Lonazolac Ca, indomethacin and NDGA on inflammatory mediator generation and release from various cells M Raulf, W König	Immunopharmacology	1990
Oxidative response of polymorphonuclear leucocytes to synovial fluids from patients with rheumatoid arthritis B Dularay, JS Badesha, PA Dieppe, CJ Elson	Annals of the rheumatic diseases	1990
Biochemistry, Molecular Biology, and Physiology of Phospholipase A2 and Its Regulatory Factors AB Mukherjee		1990
Monocyte activation in early onset rheumatoid arthritis I Fujii, M Shingu, M Nobunaga	Annals of the rheumatic diseases	1990
Effects of fish oil supplementation in rheumatoid arthritis H van der Tempel, JE Tulleken, PC Limburg, FA Muskiet, MH van Rijswijk	Annals of the rheumatic diseases	1990
Immunopharmacology Reviews JW Hadden, A Szentivanyi		1990
Effect of auranofin on eicosanoids and protein kinase C in human neutrophils T Herlin, K Fogh, NO Christiansen, K Kragballe	Agents and Actions	1989
Nutrition, Immune Function, and Inflammation: an overview JM Wan, MP Haw, GL Blackburn	Proceedings of the Nutrition Society	1989
Eicosanoid production in rheumatoid synovitis E Moilanen, J Alanko, M Nissilä, M Hämäläinen, H Isomäki, H Vapaatalo	Agents and Actions	1989
Biosynthesis, catabolism, and biological properties of HPETEs, hydroperoxide derivatives of arachidonic acid CR Pace-Asciak, S Asotra	Free radical biology & medicine	1989
Late appearance of phospholipid platelet-activating factor and leukotriene B4 in human skin after repeated antigen challenge M Shalit, FH Valone, PC Atkins, WD Ratnoff, EJ Goetzl, B Zweiman	Journal of Allergy and Clinical Immunology	1989
Leukocyte migration in synovial tissue. Leukocyte distribution, orientation, and migratory pattern after immune complex deposition in rabbit knee joints P Thomsen, LE Ericson	The American Journal of Pathology	1989
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Biochemical characterization of soluble phospholipase A2 from rheumatoid synovial fluid H Gonzalez-Buritica, DM Smith, RA Turner	Agents and Actions	1989
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Eicosanoids and rheumatology: Inflammatory and vascular aspects JJ Belch	Prostaglandins, Leukotrienes and Essential Fatty Acids	1989
Leukotriene B4Production by Peripheral Blood Neutrophils in Rheumatoid Arthritis JJ Belch, A O'dowd, D Ansell, RD Sturrock	Scandinavian Journal of Rheumatology	1989
Sulfasalazine: A potential psoriasis therapy? AK Gupta, CN Ellis, MT Siegel, JJ Voorhees	Journal of the American Academy of Dermatology	1989
15-Hydroxy-eicosatetraenoic acid (15-Hete) inhibits carragheenan-induced experimental arthritis and reduces synovial fluid leukotriene B4 (LTB4) K Fogh, ES Hansen, T Herlin, V Knudsen, TB Henriksen, H Ewald, C Bünger, K Kragballe	Prostaglandins	1989
Phospholipid metabolism in polymorphonuclear leukocytes from rheumatoid arthritis patients: Effects of non-steroidal anti-inflammatory agents and clotrimazole DM Smith, H Gonzales, JA Johnson, RC Franson, RA Turner	International Journal of Immunopharmacology	1989
Differential effects of 20-trifluoromethyl leukotriene B4 on human neutrophil functions BS Tsai, RH Keith, D Villani-Price, RA Haack, RF Bauer, R Leonard, Y Abe, KC Nicolaou	Prostaglandins	1989
Ginger (Zingiber officinale) and rheumatic disorders KC Srivastava, T Mustafa	Medical Hypotheses	1989
SC-41930: An inhibitor of leukotriene B4-stimulated human neutrophil functions BS Tsai, D Villani-Price, RH Keith, JM Zemaitis, RF Bauer, R Leonard, SW Djuric, RL Shone	Prostaglandins	1989
Characterisation of soluble and cell associated phospholipase A2 from rheumatoid synovial fluid H Gonzalez-Buritica, DM Smith, RA Turner	Annals of the rheumatic diseases	1989
Inhibition of human neutrophils by auranofin: chemotaxis and metabolism of arachidonate via the 5-lipoxygenase pathway J Elmgreen, I Ahnfelt-Ronne, OH Nielsen	Annals of the rheumatic diseases	1989
Enhanced Oxidative Response of Polymorphonuclear Leukocytes from Synovial Fluids of Patients with Rheumatoid Arthritis B Dularay, CJ Elson, PA Dieppe	Autoimmunity	1988
Investigational therapy in rheumatoid arthritis: A critical review MB Yunus	Seminars in Arthritis and Rheumatism	1988
Hydroxyeicosatetraenoic acids (HETEs) AA Spector, JA Gordon, SA Moore	Progress in Lipid Research	1988
Effects of fasting on disease activity, neutrophil function, fatty acid composition, and leukotriene biosynthesis in patients with rheumatoid arthritis I Hafström, B Ringertz, H Gyllenhammar, J Palmblad, M Harms-Ringdahl	Arthritis & Rheumatism	1988
Lipoxygenase products in experimental septic arthritis in dogs T Herlin, K Fogh, VE Knudsen, ES Hansen, E Bunger, H Ewald, I Holm, K Kragballe	APMIS	1988
Regulation of the Receptor System for Leukotriene B4on Human Neutrophils DW Goldman	Annals of the New York Academy of Sciences	1988
Perspectives on Additional Areas for Research in Leukotrienes KF Austen, RJ Soberman	Annals of the New York Academy of Sciences	1988
Receptor-specific Mechanisms for the Responses of Human Leukocytes to Leukotrienes EJ Goetzl, JW Sherman, WD Ratnoff, JP Harvey, E Eriksson, WE Seaman, L Baud, CH Koo	Annals of the New York Academy of Sciences	1988
Effects of antirheumatic drugs on leukotriene B4 and prostanoid synthesis in human polymorphonuclear leukocytesin vitro E Moilanen, J Alanko, E Seppälä, H Vapaatalo	Agents and Actions	1988
The Effects of a Novel Series of Selective Inhibitors of Arachidonate 5-Lipoxygenase on Anaphylactic and Inflammatory Responses P Bhattacherjee, NK Boughton-Smith, RL Follenfant, LG Garland, GA Higgs, HF Hodson, PJ Islip, WP Jackson, S Moncada, AN Payne, RW Randall, CH Reynolds, JA Salmon, JE Tateson, BJ Whittle	Annals of the New York Academy of Sciences	1988
Effect of single oral administrations of non steroidal antiinflammatory drugs to healthy volunteers on arachidonic acid metabolism in peripheral polymorphonuclear and mononuclear leukocytes S Colli, D Caruso, E Tremoli, E Stragliotto, G Morazzoni, G Galli	Prostaglandins, Leukotrienes and Essential Fatty Acids	1988
Effect of the 5-lipoxygenase inhibitor piriprost on superoxide production by human neutrophils J Flament, L Schandene, JM Boeynaems	Prostaglandins, Leukotrienes and Essential Fatty Acids	1988
Eicosanoids and inflammation KI Williams, GA Higgs	The Journal of Pathology	1988
The development of a sensitive and specific radioreceptor assay for leukotriene B4 F Kohi, DK Agrawal, JB Cheng, A Bewtra, RG Townley, JW Olesch	Life Sciences	1988
A Comparison of the Effect of Timegadine, Levamisole, and D-Penicillamine on Human Neutrophil Metabolism of Endogenous Arachidonic Acid and Chemotaxis OH Nielsen, I Ahnfelt-Rønne, J Elmgreen	Pharmacology & Toxicology	1988
Antirheumatic drugs and eicosanoid synthesis E Moilanen, J Alanko, E Seppälä, M Nissilä, H Isomakp, H Vapaatalo	Scandinavian Journal of Rheumatology	1988
Changes in lipoxygenase products from synovial fluid in carragheenan induced arthritis in dogs T Herlin, K Fogh, H Ewald, ES Hansen, VE Knudsen, I Holm, K Kragballe, C Bunger	APMIS	1988
Chemotactic and chemokinetic activity of Streptococcus faecalis culture supernatant for equine neutrophils AM Blancquaert, SP Colgan, WJ Bruyninckx	Veterinary Immunology and Immunopathology	1988
A comparison of effects of sulfasalazine and its metabolites on the metabolism of endogenous vs. exogenous arachidonic acid H Allgayer, WF Stenson	Immunopharmacology	1988
Mechanism of action of non-steroidal anti-rheumatic drugs M Forrest, PM Brooks	Baillière's Clinical Rheumatology	1988
Biosynthesis of 20,20,20-trifluoroleukotriene B4 from 20,20,20-trifluoroarachidonic acid: A metabolically stable analog of leukotriene B4 and its application to a study of stimulation of leukotriene B4 synthesis by immunoglobulin G Y Tanaka, TM Klauck, W Jubiz, T Taguchi, Y Hanzawa, A Igarashi, K Inazawa, Y Kobayashi, RG Briggs	Archives of Biochemistry and Biophysics	1988
Characterization of CGS 8515 as a selective 5-lipoxygenase inhibitor using in vitro and in vivo models EC Ku, A Raychaudhuri, G Ghai, EF Kimble, WH Lee, C Colombo, R Dotson, TD Oglesby, JW Wasley	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1988
New Developments in Antirheumatic Therapy KD Rainsford, GP Velo		1988
Cellular and Molecular Aspects of Inflammation G Poste, ST Crooke		1988
Eicosanoids in Inflammatory Conditions of the Lung, Skin and Joints M Church, C Robinson		1988
Immunopathogenetic Mechanisms of Arthritis JA Goodacre, WC Dick		1988
CHEMOTACTIC LEUKOTRIENE B4 ACTIVITY IN PLASMA FROM CHILDREN WITH ARTHRITIS T Herlin, K Fogh, T Ternowitz, K Storm, E Bunger	Acta Pathologica Microbiologica Scandinavica Series C: Immunology	1987
Platelet-activating factor modulates phospholipid acylation in human neutrophils J Tou	Lipids	1987
Inhibition by Leukotriene B5 of Leukotriene B4-Induced Activation of Human Keratinocytes and Neutrophils K Kragballe, JJ Voorhees, EJ Goetzl	Journal of Investigative Dermatology	1987
Leukotrienes and antileukotrienic preparations: Trends in the search and medical applications (review) LN Yakhontov, M Kaminka, LI Mastafanova, VB Nikitin, VA Azimov	Pharmaceutical Chemistry Journal	1987
Effects of dietary supplementation with marine fish oil on leukocyte lipid mediator generation and function in rheumatoid arthritis RI Sperling, M Weinblatt, JL Robin, J Ravalese, RL Hoover, F House, JS Coblyn, PA Fraser, BW Spur, DR Robinson, RA Lewis, KF Austen	Arthritis & Rheumatism	1987
Production of 5-lipoxygenase pathway metabolites by peripheral leucocytes in capillary leak syndrome (Clarkson disease) E Rondeau, J Sraer, M Bens, LM Doleris, R Lacave, JD Sraer	European Journal of Clinical Investigation	1987
Chemotactic activity in aqueous humor from patients with anterior uveitis JT Rosenbaum, WW Raymond, LS Fujikawa, L Langlois, AG Palestine, RL Stamper, WR Freeman, J Deschenes, C Sell, JR Samples, JA Parker, RA Nozik, DH Char, RB Nussenblatt	Clinical Immunology and Immunopathology	1987
Lipoxygenase products from polymorphonuclear leukocytes and epithelial cells of human saliva FA Green, HE Claesson, M Hamberg	Archives of Biochemistry and Biophysics	1987
Development of a system for evaluating 5-lipoxygenase inhibitors using human whole blood FJ Sweeney, JD Eskra, TJ Carty	Prostaglandins, Leukotrienes and Medicine	1987
The metabolism leukotriene B4 in synovial fluid and whole human blood MJ Forrest, D Burton, PM Brooks	Prostaglandins	1987
Purified human basophils do not generate LTB4 JA Warner, HS Freeland, DW MacGlashan, LM Lichtenstein, SP Peters	Biochemical Pharmacology	1987
Isolation and analysis of complement activating aggregates from synovial fluid of patients with rheumatoid arthritis using monoclonal anti-C3d antibodies AE Bedwell, CJ Elson, SD Carter, PA Dieppe, CW Hutton, R Czudek	Annals of the rheumatic diseases	1987
Enhanced capacity for release of leucotriene B4 by neutrophils in rheumatoid arthritis J Elmgreen, OH Nielsen, I Ahnfelt-Ronne	Annals of the rheumatic diseases	1987
Alterations in neutrophil superoxide production following piroxicam therapy in patients with rheumatoid arthritis DE Epps, S Greiwe, J Potter, J Goodwin	Inflammation	1987
Chemotactic activity in inflammatory bowel disease: Role of leukotriene B4 EA Lobos, P Sharon, WF Stenson	Digestive Diseases and Sciences	1987
Neuronal response thresholds to and encoding of thermal stimuli during carrageenin-hyperalgesic-inflammation in the ventro-basal thalamus of the rat G Guilbaud, JM Benoist, A Neil, V Kayser, M Gautron	Experimental Brain Research	1987
Leukotrienes in inflammation MA Bray	Agents and Actions	1986
Enhanced phospholipase activity in peripheral blood monocytes from patients with rheumatoid arthritis JS Bomalaski, MA Clark, RB Zurier	Arthritis & Rheumatism	1986
Acylation of docosahexaenoic acid into phospholipids by intact human neutrophils J Tou	Lipids	1986
Interleukin-1 lymphocyte chemotactic activity in rheumatoid arthritis synovial fluid P Miossec, CA Dinarello, M Ziff	Arthritis & Rheumatism	1986
Topical steroid treatment reduces arachidonic acid and leukotriene B4 in lesional skin of psoriasis E Wong, RM Barr, FM Cunningham, K Mistry, PM Woollard, AI Mallet, MW Greaves	British Journal of Clinical Pharmacology	1986
Pharmacological profiles of a potential LTB4-antagonist, SM-9064 M Namiki, Y Igarashi, K Sakamoto, T Nakamura, Y Koga	Biochemical and Biophysical Research Communications	1986
The role of eicosanoids in inflammation GA Higgs	Progress in Lipid Research	1986
Species-dependent regulation of monocyte/macrophage Ia antigen expression and antigen presentation by prostaglandin E SL Kunkel, DA Campbell, SW Chensue, GI Higashi	Cellular Immunology	1986
Hydroxy fatty acids and prostaglandin formation in diseased human periodontal pocket tissue TM Elattar, HS Lin, WJ Killoy, JY Vanderhoek, JM Goodson	Journal of Periodontal Research	1986
Metabolism of leukotrienes B4 and B5 by human polymorphonuclear leukocytes T Terano, H Saito, JA Salmon, S Moncada	Progress in Lipid Research	1986
Difference in the in vitro metabolism of leukotrienes in the exudates from allergic and nonallergic rat pleurisies A Ueno, K Tanaka, M Katori	Prostaglandins	1986
Leukotriene B4 and 20-OH-LTB4 in purulent peritoneal exudates demonstrated by GC-MS Y Kikawa, Y Shigematsu, M Sudo	Prostaglandins, Leukotrienes and Medicine	1986
Leukotriene B4 potentiates airway muscle responsiveness and JE Thorpe, CG Murlas	Prostaglandins	1986
1: Arachidonic Acid Metabolism in Inflammation and Hypersensitivity Reactions: A Brief Introduction CL Malmsten	Cephalalgia : an international journal of headache	1986
Clinical Endocrinology A Labhart	Clinical Endocrinology	1986
Effects of dietary fish oil supplementation on polymorphonuclear leukocyte inflammatory potential M Fisher, KS Upchurch, PH Levine, MH Johnson, CH Vaudreuil, A Natale, JJ Hoogasian	Inflammation	1986
Therapeutics in Rheumatology JM Moll, HA Bird, A Rushton		1986
Eicosanoide und Phospholipasen M Goerig, AJ Habenicht, G Schettler	Klinische Wochenschrift	1985
The relation of leukotrienes to liver injury D Keppler, W Hagmann, S Rapp, C Denzlinger, HK Koch	Hepatology	1985
Leukotrienes J Ophir, S Brenner, S Kivity	International Journal of Dermatology	1985
Prostaglandins, thromboxanes, and leukotrienes in inflammation CL Malmsten	Seminars in Arthritis and Rheumatism	1985
Prostaglandins, thromboxanes and leukotrienes in clinical medicine RD Zipser, G Laffi	The Western journal of medicine	1985
Stimulation by lipoxygenase products of superoxide anion production in FMLP-treated neutrophils JK Beckman, JC Gay, AR Brash, JN Lukens, JA Oates	Lipids	1985
Production of leukotrienes and prostaglandins by human ascites cells RJ Ouwendijk, FJ Zijlstra, JH Wilson, JE Vincent, IL Bonta	European Journal of Clinical Investigation	1985
Models for evaluating the anti-inflammatory effects of inhibitors of arachidonic acid metabolism A Blackham, AA Norris, FA Woods	Journal of Pharmacy and Pharmacology	1985
Leukotriene A5 is a substrate and an inhibitor of rat and human neutrophil LTA4 hydrolase DJ Nathaniel, JF Evans, Y Leblanc, C Léveillé, BJ Fitzsimmons, AW Ford-Hutchinson	Biochemical and Biophysical Research Communications	1985
Generation of leukotrienes from normal epidermis and their demonstration in cutaneous disease T Rosenbach, J Grabbe, AN MoLLER, HJ Schwanitz, BM Czarnetzki	British Journal of Dermatology	1985
Increased activity of 5-lipoxygenase in polymorphonuclear leukocytes from asthmatic patients H Mita, Y Yui, N Taniguchi, H Yasueda, T Shida	Life Sciences	1985
Immunoregulation by leukotrienes and other lipoxygenase metabolites M Rola-Pleszczynski	Immunology Today	1985
Oxidative Stress A Stern	Oxidative Stress	1985
Metabolism of Arachidonic Acid in Acetic Acid Colitis in Rats P Sharon, WF Stenson	Gastroenterology	1985
Disappearance and metabolism of leukotriene B4 during carrageenan-induced pleurisy BM Taylor, FF Sun	Biochemical Pharmacology	1985
Biochemistry of Arachidonic Acid Metabolism WE Lands		1985
Inflammatory Mediators GA Higgs, TJ Williams		1985
Leukotriene A3. A poor substrate but a potent inhibitor of rat and human neutrophil leukotriene A4 hydrolase JF Evans, DJ Nathaniel, RJ Zamboni, AW Ford-Hutchinson	The Journal of biological chemistry	1985
Leukotrienes in Disease Implications for Drug Development: GA Higgs, S Moncada	Drugs	1985
The biologically active leukotrienes. Biosynthesis, metabolism, receptors, functions, and pharmacology RA Lewis, KF Austen	Journal of Clinical Investigation	1984
Role of lipoxygenase products in murine pulmonary granuloma formation SL Kunkel, SW Chensue, C Mouton, GI Higashi	Journal of Clinical Investigation	1984
Leukotriene B4 stimulates polymorphonuclear leukocyte adhesion to cultured vascular endothelial cells MA Gimbrone, AF Brock, AI Schafer	Journal of Clinical Investigation	1984
Immunopathogenetic roles of leukotrienes in human diseases EJ Goetzl, DG Payan, DW Goldman	Journal of Clinical Immunology	1984
Arachidonic Acid Metabolism and Inflammation a brief Introduction C Malmsten	Scandinavian Journal of Rheumatology	1984
Mechanism of action of leukotriene B4: Intracellular calcium redistribution in rabbit neutrophils PH Naccache, TF Molski, P Borgeat, RI Sha'afi	Journal of Cellular Physiology	1984
Inhibition of tissue damage by the arachidonate lipoxygenase inhibitor BW755C GA Higgs, KG Mugridge, S Moncada, JR Vane	Proceedings of the National Academy of Sciences	1984
Effects of auranofin on leukotriene production and leukotriene stimulated neutrophil function I Hafström, B Ringertz, J Palmblad, C Malmsten	Agents and Actions	1984
Leukotriene involvement in pathologic processes AW Ford-Hutchinson	Journal of Allergy and Clinical Immunology	1984
Leukotriene B4 is an incomplete agonist for the activation of human neutrophils SM Prescott, GA Zimmerman, AR Seeger	Biochemical and Biophysical Research Communications	1984
The arachidonic acid cascade E Granstr�m	Inflammation	1984
Leukotrienes and Prostaglandins in Asthma H Bisgaard	Allergy	1984
Leukotrienes reduce nociceptive responses to bradykinin A Schweizer, R Brom, M Glatt, MA Bray	European Journal of Pharmacology	1984
Reduction by dexamethasone of chemotactic activity in inflammatory exudates A Kurihara, K Ohuchi, S Tsurufuji	European Journal of Pharmacology	1984
Biosynthesis and biological activity of leukotriene B5 T Terano, JA Salmon, S Moncada	Prostaglandins	1984
Effect of orally administered eicosapentaenoic acid (EPA) on the formation of leukotriene B4 and leukotriene B5 by rat leukocytes T Terano, JA Salmon, S Moncada	Biochemical Pharmacology	1984
Leukotrienes: Clinical significance ME Goldyne	Journal of the American Academy of Dermatology	1984
Prostaglandin-generating factor of anaphylaxis induces mucous glycoprotein release and the formation of lipoxygenase products of arachidonate from human airways Z Marom, JH Shelhamer, L Steel, EJ Goetzl, M Kaliner	Prostaglandins	1984
Leukotriene B4, polymorphonuclear leukocytes and inflammatory exudates in the rat AW Ford-Hutchinson, G Brunet, P Savard, S Charleson	Prostaglandins	1984
Aspirin and the Salicylates KD Rainsford	Aspirin and the Salicylates	1984
The Leukotrienes A Leitch, J Drazen	The Leukotrienes	1984
Soybean lipoxygenase inhibition: Studies with the sulphasalazine metabolites N-acetylaminosalicylic acid, 5-aminosalicylic acid and sulphapyridine H Allgayer, J Eisenburg, G Paumgartner	European Journal of Clinical Pharmacology	1984
Differential effects of putative lipoxygenase inhibitors on arachidonic acid metabolism in cell-free and intact cell preparations J Chang, MD Skowronek, ML Cherney, AJ Lewis	Inflammation	1984
Membrane Processes G Benga, H Baum, FA Kummerow		1984
Enhanced Synthesis of Leukotriene B4 by Colonic Mucosa in Inflammatory Bowel Disease P Sharon, WF Stenson	Gastroenterology	1984
The effect of eicosapentaenoic acid on leukotriene B production by human neutrophils SM Prescott	The Journal of biological chemistry	1984
The arachidonic acid cascade: The prostaglandins, thromboxanes and leukotrienes E Granstrm	Inflammation	1984
The effects of BW755C and other anti-inflammatory drugs on eicosanoid concentrations and leukocyte accumulation in experimentally-induced acute inflammation JA Salmon, PM Simmons, S Moncada	Journal of Pharmacy and Pharmacology	1983
ARACHIDONIC ACID, LEUKOTRIENE B4, AND NEUTROPHIL ACTIVATION PH Naccache, RI Sha'afi	Annals of the New York Academy of Sciences	1983
Responses of human skin to intradermal injection of leukotrienes C4, D4 and B4 RD Camp, AA Coutts, MW Greaves, AB Kay, MJ Walport	British Journal of Pharmacology	1983
New Comprehensive Biochemistry S Yamamoto	New Comprehensive Biochemistry	1983
Arachidonic acid metabolism by rabbit synovial cells in culture RJ Rothenberg, RW Moskowitz, CJ Malemud	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1983
Detection of leukotriene C4 and D4 in the exudate of rat carrageenin-induced pleurisy A Ueno, K Tanaka, M Katori	Prostaglandins	1983
The release of leukotriene B4 during experimental inflammation PM Simmons, JA Salmon, S Moncada	Biochemical Pharmacology	1983
Arachidonic Acid Metabolism and Macrophage Activation SW Chensue, SL Kunkel	Clinics in Laboratory Medicine	1983
Leukotriene B4, a mediator of inflammation present in synovial fluid in rheumatoid arthritis EM Davidson, SA Rae, MJ Smith	Annals of the rheumatic diseases	1983
A novel dioxygenation product of arachidonic acid possesses potent chemotactic activity for human polymorphonuclear leukocytes S Shak, HD Perez, IM Goldstein	The Journal of biological chemistry	1983
Leukotrienes, allergy and inflammation FP Nijkamp, JM Sitsen	Pharmaceutisch Weekblad Scientific Edition	1982
Radioimmunoassay for leukotriene B4 RA Lewis, JM Mencia-Huerta, RJ Soberman, D Hoover, A Marfat, EJ Corey, KF Austen	Proceedings of the National Academy of Sciences	1982
Inhibition of leukotriene B4-induced neutrophil degranulation by leukotriene B4-dimethylamide HJ Showell, IG Otterness, A Marfat, EJ Corey	Biochemical and Biophysical Research Communications	1982
Leukotriene B4 in synovial fluid EM Davidson, SA Rae, MJ Smith	Journal of Pharmacy and Pharmacology	1982
Prostaglandins, hydroxy fatty acids, leukotrienes and inflammation of the skin R Camp	Clinical and Experimental Dermatology	1982
Indomethacin-responsive mononuclear cell dysfunction in “atypical” mycobacteriosis UG Mason, LE Greenberg, SS Yen, CH Kirkpatrick	Cellular Immunology	1982
A radioimmunoassay for leukotriene B4 JA Salmon, PM Simmons, RM Palmer	Prostaglandins	1982
Platelet lipoxygenase-dependent oxygen burst evidence for differential activation of lipoxygenase in intact and disrupted human platelets AI Schafer, NA Turner, RI Handin	Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism	1982
Testosterone inhibits prostaglandin formation by human gingival connective tissue: Relationship to 14C-arachidonic acid metabolism TM ElAttar, HS Lin, DE Tira	Prostaglandins, Leukotrienes and Medicine	1982
Deficiency of Platelet Lipoxygenase Activity in Myeloproliferative Disorders AI Schafer	New England Journal of Medicine	1982
Biochemical Immunological Pharmacology PE Lipsky	Biochemical Immunological Pharmacology	1982
Control of vascular permeability by polymorphonuclear leukocytes in inflammation CV Wedmore, TJ Williams	Nature	1981
Mediation of local homeostasis and inflammation by leukotrienes and other mast cell-dependent compounds RA Lewis, KF Austen	Nature	1981
Leukotriene B4 and neutrophil function: a review AW Ford-Hutchinson	Journal of the Royal Society of Medicine	1981
Chronic inflammation in adjuvant arthritic rats correlates with enhancement of 12-l-HETE-synthesis I Ahnfelt-Rønne, E Bramm, E Arrigoni-Martelli	Agents and Actions	1981
Biological activities of leukotriene B4 MJ Smith	Agents and Actions	1981
Chemotactic response to some arachidonic acid lipoxygenase products in the rabbit eye P Bhattacherjee, B Hammond, JA Salmon, R Stepney, KE Eakins	European Journal of Pharmacology	1981
A Stereocontrolled and effective synthesis of leukotriene B () EJ Corey, A Marfat, J Munroe, KS Kim, PB Hopkins, F Brion	Tetrahedron Letters	1981
Leukotriene B4 MJ Smith	General Pharmacology: The Vascular System	1981
Oxygenation Products of Arachidonic Acid as Mediators of Hypersensitivity and Inflammation EJ Goetzl	Medical Clinics of North America	1981
Neutrophil Function and Dysfunction P Cole, AJ Williams	Journal of the Royal Society of Medicine	1981
Leukotriene B 4 and Neutrophil Function: A Review AW Ford-Hutchinson	Journal of the Royal Society of Medicine	1981
Ergebnisse der Inneren Medizin und Kinderheilkunde / Advances in Internal Medicine and Pediatrics P Frick, GA von Harnack, GA Martini, A Prader, HP Wolff		1980
Advances in Lipid Research AM Scanu	Advances in Lipid Research	1965

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