Citations to this article

Iodothyronine Release from the Perfused Canine Thyroid following Cessation of Stimulation: RAPID DECLINE OF TRIIODOTHYRONINES IN COMPARISON WITH THYROXINE
Peter Laurberg
Peter Laurberg
Published February 1, 1980
Citation Information: J Clin Invest. 1980;65(2):488-495. https://doi.org/10.1172/JCI109692.
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Iodothyronine Release from the Perfused Canine Thyroid following Cessation of Stimulation: RAPID DECLINE OF TRIIODOTHYRONINES IN COMPARISON WITH THYROXINE

Abstract

The kinetics of thyroid secretion after termination of stimulation by 100 μU/ml bovine thyroid stimulating hormone (TSH) or 5 mM cyclic AMP (cAMP) were studied using perfused canine thyroid lobes. All experiments were performed as paired comparisons, one thyroid lobe acting as a control continuing to receive infusion of the stimulator. 2.5 h after termination of TSH infusion, the secretion of thyroxine (T4), 3,5,3′-triiodothyronine (T3), and 3,3′,5′-triiodothyronine (rT3) was not significantly different from that of the control lobes. After cessation of cAMP infusion, the secretion of T4 continued unaffected for ∼40 min. Then a gradual decline in T4 release occurred. The secretion of T3 and rT3 decreased somewhat earlier leading to a transient phase with increases in the T4:T3 and T4:rT3 ratios in the thyroid effluent.

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Peter Laurberg

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Year: 2011 2003 1997 1985 1984 1983 Total
Citations: 1 1 1 1 2 2 8
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Citations to this article (8)

Title and authors Publication Year
Increased thyroidal T4 to T3 conversion in autonomously functioning thyroid adenoma: From euthyroidism to thyrotoxicosis
M Solter, L Posavec, D Solter, V Vargek-Solter 		Annales d'Endocrinologie 2011
Thyroid status in pregnant Mauritian women
AH Subratty, Y Peerbacus 		Nutrition & Food Science 2003
The Regulation of Thyroid Function in Pregnancy: Pathways of Endocrine Adaptation from Physiology to Pathology
D Glinoer 		Endocrine reviews 1997
Contemporary Endocrinology
SH Ingbar 		1985
Mechanisms governing the relative proportions of thyroxine and 3,5,3′-triiodothyronine in thyroid secretion
P Laurberg 		Metabolism 1984
Thyroid Function Tests in the Dog: Recent Concepts
DC Ferguson 		Veterinary Clinics of North America Small Animal Practice 1984
THYROID HORMONE SECRETION RATES: RESPONSE TO ENDOGENOUS AND EXOGENOUS TSH IN MAN DURING SURGERY
L Tegler, J Gillquist, R Lindvall, S Almqvist, P Roos 		Clinical Endocrinology 1983
Thyroidal release after oral administration of TRH in normal subjects
J Golstein, D Glinoer, M Bonnyns, L Vanhaelst 		Journal of Endocrinological Investigation 1983

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