Plasma from individuals with high molecular weight (HMW) kininogen deficiency has been reported to be deficient in prekallikrein as measured by radial immunodiffusion, prekallikrein coagulant activity, and/or kaolin-activated arginine esterase activity. The discovery that prekallikrein and HMW kininogen circulate as a complex in plasma led us to reevaluate the antigenic and functional properties of prekallikrein in HMW kininogen-deficient plasma as well as in normal plasma.
Cheryl F. Scott, Robert W. Colman
Title and authors | Publication | Year |
---|---|---|
Blocking domain 6 of high molecular weight kininogen to understand intrinsic clotting mechanisms.
Singh PK, Chen ZL, Horn K, Norris EH |
Research and Practice in Thrombosis and Haemostasis | 2022 |
The complex role of kininogens in hereditary angioedema.
Kaplan AP, Joseph K, Ghebrehiwet B |
2022 | |
The Influence of Plasma Prekallikrein Oligonucleotide Antisense Therapy on Coagulation and Fibrinolysis Assays: A Post-hoc Analysis.
Fijen LM, Petersen RS, Meijers JCM, Bordone L, Levi M, Cohn DM |
Thrombosis and haemostasis | 2022 |
Blood Clotting and the Pathogenesis of Types I and II Hereditary Angioedema
S de Maat, K Joseph, C Maas, AP Kaplan |
Clinical Reviews in Allergy & Immunology | 2021 |
Resolving Differential Diagnostic Problems in von Willebrand Disease, in Fibrinogen Disorders, in Prekallikrein Deficiency and in Hereditary Hemorrhagic Telangiectasia by Next-Generation Sequencing
R Gindele, A Kerényi, J Kállai, G Pfliegler, Á Schlammadinger, I Szegedi, T Major, Z Szabó, Z Bagoly, C Kiss, J Kappelmayer, Z Bereczky |
Life Sciences | 2021 |
Pathophysiology and underlying mechanisms in hereditary angioedema.
López Lera A |
Balkan Medical Journal | 2021 |
Severe high-molecular-weight kininogen deficiency due to a homozygous c.1456C > T nonsense variant in a large Chinese family
J Yang, L Fan, Y Qiao, Y Zhao, T Zhu |
Journal of Thrombosis and Thrombolysis | 2020 |
Plasma kallikrein contributes to ambient particulate matter-induced lung injury
B Wang, X Yan, F Chen, A Yang, Y Lu, Y Wu |
Biochemical and Biophysical Research Communications | 2019 |
Complement, Kinins, and Hereditary Angioedema: Mechanisms of Plasma Instability when C1 Inhibitor is Absent
AP Kaplan, K Joseph |
Clinical Reviews in Allergy & Immunology | 2016 |
Polyphosphate colocalizes with factor XII on platelet-bound fibrin and augments its plasminogen activator activity
JL Mitchell, AS Lionikiene, G Georgiev, A Klemmer, C Brain, PY Kim, NJ Mutch |
Blood | 2016 |
A Cross-sectional Study of KLKB1 and PRCP Polymorphisms in Patient Samples with Cardiovascular Disease
HR Gittleman, A Merkulova, O Alhalabi, EX Stavrou, ML Veigl, JS Barnholtz-Sloan, AH Schmaier |
Frontiers in Medicine | 2016 |
Reduced thrombosis in Klkb1-/- mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor
EX Stavrou, C Fang, A Merkulova, O Alhalabi, N Grobe, S Antoniak, N Mackman, AH Schmaier |
Blood | 2014 |
Comprehensive Physiology
SN Cheuvront, RW Kenefick |
Comprehensive Physiology | 2014 |
Tracking down contact activation - from coagulation in vitro to inflammation in vivo
S Maat, C Tersteeg, E Herczenik, C Maas |
International Journal of Laboratory Hematology | 2014 |
Bacteria under stress by complement and coagulation
ET Berends, A Kuipers, MM Ravesloot, RT Urbanus, SH Rooijakkers |
FEMS Microbiology Reviews | 2014 |
The kinin–kallikrein system: physiological roles, pathophysiology and its relationship to cancer biomarkers
E Kashuba, J Bailey, D Allsup, L Cawkwell |
Biomarkers | 2013 |
Factor XII–independent activation of the bradykinin-forming cascade: Implications for the pathogenesis of hereditary angioedema types I and II
K Joseph, BG Tholanikunnel, A Bygum, B Ghebrehiwet, AP Kaplan |
Journal of Allergy and Clinical Immunology | 2013 |
Structural Requirements for the Procoagulant Activity of Nucleic Acids
J Gansler, M Jaax, S Leiting, B Appel, A Greinacher, S Fischer, KT Preissner, MP Bachmann |
PloS one | 2012 |
Methods in Enzymology
JD Stone, AS Chervin, DH Aggen, DM Kranz |
Protein Engineering for Therapeutics Part B | 2012 |
Advances in Immunology
E Pinaud, M Marquet, R Fiancette, S Péron, C Vincent-Fabert, Y Denizot, M Cogné |
Advances in Immunology Volume 110 | 2011 |
Structure and function of factor XI
J Emsley, PA McEwan, D Gailani |
Blood | 2010 |
Congenital prekallikrein deficiency
A Girolami, P Scarparo, N Candeo, AM Lombardi |
Expert Review of Hematology | 2010 |
xPharm: The Comprehensive Pharmacology Reference
A Vinh |
xPharm: The Comprehensive Pharmacology Reference | 2010 |
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
Factor XII–independent cleavage of high-molecular-weight kininogen by prekallikrein and inhibition by C1 inhibitor
K Joseph, BG Tholanikunnel, AP Kaplan |
Journal of Allergy and Clinical Immunology | 2009 |
Characterization of molecular defects of Fitzgerald trait and another novel high-molecular-weight kininogen-deficient patient: insights into structural requirements for kininogen expression
Y Krijanovski |
Blood | 2003 |
Human Kininogen Gene Is Transactivated by the Farnesoid X Receptor
A Zhao, JL Lew, L Huang, J Yu, T Zhang, Y Hrywna, JR Thompson, N Pedro, RA Blevins, F Peláez, SD Wright, J Cui |
The Journal of biological chemistry | 2003 |
Factor XI, but Not Prekallikrein, Blocks High Molecular Weight Kininogen Binding to Human Umbilical Vein Endothelial Cells
TR Baird, PN Walsh |
The Journal of biological chemistry | 2003 |
Chronic intestinal inflammation and angiogenesis in genetically susceptible rats is modulated by kininogen deficiency
I Isordia-Salas, RA Pixley, F Li, I Sainz, RB Sartor, A Adam, RW Colman |
International Immunopharmacology | 2002 |
Kininogen deficiency modulates chronic intestinal inflammation in genetically susceptible rats
I Isordia-Salas, RA Pixley, F Li, I Sainz, RB Sartor, A Adam, RW Colman |
AJP Gastrointestinal and Liver Physiology | 2002 |
High Molecular Weight Kininogen Regulates Prekallikrein Assembly and Activation on Endothelial Cells: A Novel Mechanism for Contact Activation
G Motta, R Rojkjaer, AA Hasan, DB Cines, AH Schmaier |
Blood | 1998 |
Significance of the Regulation of Plasma Kallikrein by ?2M
RW Colman |
Annals of the New York Academy of Sciences | 1994 |
The shape of high molecular weight kininogen. Organization into structural domains, changes with activation, and interactions with prekallikrein, as determined by electron microscopy
JW Weisel, C Nagaswami, JL Woodhead, RA Cadena, JD Page, RW Colman |
The Journal of biological chemistry | 1994 |
Domain 3 of kininogens contains a cell-binding site and a site that modifies thrombin activation of platelets
YP Jiang, W Muller-Esterl, AH Schmaier |
The Journal of biological chemistry | 1992 |
Contact activation factors in plasma from pregnant women-increased level of an association between factor XII and kallikrein
K Briseid, NO Hoem, S Johannesen, S Fossum |
Thrombosis Research | 1991 |
Low molecular weight kininogen binds to platelets to modulate thrombin-induced platelet activation
FJ Meloni, AH Schmaier |
The Journal of biological chemistry | 1991 |
Localization of distinct functional domains on prekallikrein for interaction with both high molecular weight kininogen and activated factor XII in a 28-kDa fragment (amino acids 141-371)
JD Page, RW Colman |
The Journal of biological chemistry | 1991 |
The inositol-phospholipid-accelerated activation of prekallikrein by activated factor XII at physiological ionic strength requires zinc ions and high-Mr kininogen
I SCHOUSBOE |
European Journal of Biochemistry | 1990 |
Functional correlation between kallikrein and factor XII activated in human plasma
K Briseid, NO Hoem, S Johannesen, K Marthinsen |
Thrombosis Research | 1990 |
A new case of total kininogen deficiency
H Stormorken, K Briseid, B Hellum, NO Hoem, HT Johansen, B Ly |
Thrombosis Research | 1990 |
1 Mechanism of heparin action
CM Jackson |
Baillière's Clinical Haematology | 1990 |
6 Mechanism of action of the thrombolytic agents
JI Weitz |
Baillière's Clinical Haematology | 1990 |
Human neutrophils contain and bind high molecular weight kininogen
EJ Gustafson, AH Schmaier, YT Wachtfogel, N Kaufman, U Kucich, RW Colman |
Journal of Clinical Investigation | 1989 |
Kinins V
K Abe, H Moriya, S Fujii |
1989 | |
A Prospective Study of Platelets and Plasma Proteolytic Systems during the Early Stages of Rocky Mountain Spotted Fever
AK Rao, M Schapira, ML Clements, S Niewiarowski, AZ Budzynski, AH Schmaier, PC Harpel, WC Blackwelder, JR Scherrer, E Sobel, RW Colman |
New England Journal of Medicine | 1988 |
The expression of high molecular weight kininogen on human umbilical vein endothelial cells
AH Schmaier, A Kuo, D Lundberg, S Murray, DB Cines |
The Journal of biological chemistry | 1988 |
Initiation of Blood Coagulation at Artificial Surfaces
RW Colman, CF Scott, AH Schmaier, YT Wachtfogel, RA Pixley, LH Edmunds |
Annals of the New York Academy of Sciences | 1987 |
Determination of the bifunctional properties of high molecular weight kininogen by studies with monoclonal antibodies directed to each of its chains
AH Schmaier, D Schutsky, A Farber, LD Silver, HN Bradford, RW Colman |
The Journal of biological chemistry | 1987 |
The contact activation system: Biochemistry and interactions of these surface-mediated defense reactions
RW Colman, AH Schmaier, OD Ratnoff |
Critical Reviews in Oncology/Hematology | 1986 |
A new case of high-molecular-weight kininogen inherited deficiency
JJ Lefrère, MH Horellou, D Gozin, J Conard, JY Muller, M Clark, JP Soulier, M Samama |
American Journal of Hematology | 1986 |
Kinins IV
LM Greenbaum, HS Margolius |
1986 | |
Antibodies to human plasma kallikrein from egg yolks of an immunized hen: Preparation and characterization
D Burger, MA Ramus, M Schapira |
Thrombosis Research | 1985 |
Immunology of Rheumatic Diseases
S Gupta, N Talal |
1985 | |
Protein-protein interactions in contact activation of blood coagulation. Binding of high molecular weight kininogen and the 5-(iodoacetamido) fluorescein-labeled kininogen light chain to prekallikrein, kallikrein, and the separated kallikrein heavy and light chains
PE Bock, JD Shore, G Tans, JH Griffin |
The Journal of biological chemistry | 1985 |
Surface-mediated defense reactions. The plasma contact activation system
RW Colman |
Journal of Clinical Investigation | 1984 |
The effect of high molecular weight kininogen on surface-adsorbed fibrinogen
AH Schmaier, L Silver, AL Adams, GC Fischer, PC Munoz, L Vroman, RW Colman |
Thrombosis Research | 1984 |
Interaction of human plasma kallikrein and its light chain with .alpha.2-macroglobulin
FV der Graaf, A Rietveld, FJ Keus, BN Bouma |
Biochemistry | 1984 |
High-molecular weight kininogen. A secreted platelet protein
AH Schmaier, A Zuckerberg, C Silverman, J Kuchibhotla, GP Tuszynski, RW Colman |
Journal of Clinical Investigation | 1983 |
Prekallikrein Activation and High-Molecular-Weight Kininogen Consumption in Hereditary Angioedema
M Schapira, LD Silver, CF Scott, AH Schmaier, LJ Prograis, JG Curd, RW Colman |
New England Journal of Medicine | 1983 |
Interaction of human plasma kallikrein and its light chain with C.hivin.1 inhibitor
FV der Graaf, JA Koedam, JH Griffin, BN Bouma |
Biochemistry | 1983 |
The Physiology of Hemostasis
D Ogston |
1983 | |
Inactivation of factor XIa by plasma protease inhibitors: predominant role of alpha 1-protease inhibitor and protective effect of high molecular weight kininogen
CF Scott, M Schapira, HL James, AB Cohen, RW Colman |
Journal of Clinical Investigation | 1982 |
Immunoelectrophoretic studies of prekallikrein in human plasma
WE Hathaway, J Christian, R McGregor, C Borden |
Thrombosis Research | 1982 |
High molecular weight kininogen or its light chain protects human plasma kallikrein from inactivation by plasma protease inhibitors
M Schapira, CF Scott, A James, LD Silver, F Kueppers, HL James, RW Colman |
Biochemistry | 1982 |
REGULATION OF THE FORMATION AND INHIBITION OF HUMAN PLASMA KALLIKREIN*
RW Colman, M Schapira, CF Scott |
Annals of the New York Academy of Sciences | 1981 |
Heterogeneity of Human Prekallikrein Deficiency (Fletcher Trait): Evidence That Five of 18 Cases Are Positive for Cross-Reacting Material
H Saito, LT Goodnough, J Soria, C Soria, J Aznar, F España |
New England Journal of Medicine | 1981 |
Protection of human plasma kallikrein from inactivation by c.hivin.1 inhibitor and other protease inhibitors. The role of high molecular weight kininogen
M Schapira, CF Scott, RW Colman |
Biochemistry | 1981 |
Blut und Blutkrankheiten
L Heilmeyer, K Betke, KG von Boroviczény, D Busch, E Grundmann, H Heimpel, G Hoffmann, W Hunstein, W Keiderling, M Matthes, H Merker, W Müller, P Pfannenstiel |
1968 |