A rabbit model was used to study the effects of neutropenia and inflammation on the intravascular distribution, survival, and tissue accumulation of transfused neutrophils. Donor blood labeled with [3H]thymidine was infused into normal or neutropenic (vinblastine treated) animals. Inflammation was created by subcutaneous implantation of polyvinyl sponges, some with added endotoxin. Initial circulating neutrophil pool recovery, survival, and inflammatory site accumulation of labeled neutrophils were measured.
Marc S. Rosenshein, Thomas H. Price, David C. Dale
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Role of tumor-associated neutrophils in regulation of tumor growth in lung cancer development: A mathematical model
Y Kim, D Lee, J Lee, S Lee, S Lawler, E Demidenko |
PloS one | 2019 |
Expression of either Lethal Toxin or Edema Toxin by Bacillus anthracis Is Sufficient for Virulence in a Rabbit Model of Inhalational Anthrax
JA Lovchik, M Drysdale, TM Koehler, JA Hutt, CR Lyons, SR Blanke |
Infection and immunity | 2012 |
Homeostatic Regulation of Blood Neutrophil Counts
S von Vietinghoff, K Ley |
Journal of immunology (Baltimore, Md. : 1950) | 2008 |
Contributions of Histamine, Prostanoids, and Neurokinins to Edema Elicited by Edema Toxin from Bacillus anthracis
J Tessier, C Green, D Padgett, W Zhao, L Schwartz, M Hughes, E Hewlett |
Infection and immunity | 2007 |
Cerulein-Induced Acute Pancreatitis in the Rat is Significantly Ameliorated by Treatment With MEK1/2 Inhibitors U0126 and PD98059
AP Clemons, DM Holstein, A Galli, C Saunders |
Pancreas | 2002 |
Functional Distinction between CXC Chemokines, Interleukin-8 (IL-8), and Growth Related Oncogene (GRO)α in Neutrophil Infiltration
K Fujiwara, A Matsukawa, S Ohkawara, K Takagi, M Yoshinaga |
Laboratory Investigation | 2002 |
Involvement of CXC Chemokine Growth-Related Oncogene-α in Monosodium Urate Crystal-Induced Arthritis in Rabbits
K Fujiwara, S Ohkawara, K Takagi, M Yoshinaga, A Matsukawa |
Laboratory Investigation | 2002 |
Acute Host-Mediated Endothelial Injury After Adenoviral Gene Transfer in Normal Rabbit Arteries: Impact on Transgene Expression and Endothelial Function
KM Channon, HS Qian, SA Youngblood, E Olmez, GA Shetty, V Neplioueva, MA Blazing, SE George |
Circulation research | 1998 |
Neutrophil migrationin vivoandin vitroin healthy neutropenic subjects
PV Koivuranta-Vaara, H Repo |
APMIS | 1988 |
Degradation of heparan sulfate in the subendothelial extracellular matrix by a readily released heparanase from human neutrophils. Possible role in invasion through basement membranes
Y Matzner, M Bar-Ner, J Yahalom, R Ishai-Michaeli, Z Fuks, I Vlodavsky |
Journal of Clinical Investigation | 1985 |
Gram-positive bacteria-induced granulocytopenia and pulmonary leukostasis in rabbits
SE Goldblum, WP Reed |
Infection and immunity | 1982 |
Neutrophil-endothelial cell interactions on endothelial monolayers grown on micropore filters
RF Taylor, TH Price, SM Schwartz, DC Dale |
Journal of Clinical Investigation | 1981 |