Go to
JCI Insight
Citations to this article
Abstract
Amino acids and peptides release gastrin and stimulate gastric acid secretion. However, the relation between gastrin release and acid secretory response is unclear. An isotonic mixed amino acid solution (casein hydrolysate) was continuously infused into the stomach of eight healthy human subjects. Acid secretion, measured by in vivo intragastric titration, increased 12.8 meq/h over the response to intragastric infusion of isotonic saline. Plasma gastrin heptadecapeptide (G-17) concentration, measured by specific radioimmunoassay, increased 13 pmol/liter during intragastric amino acid infusion.
Authors
Mark Feldman, John H. Walsh, Helen C. Wong, Charles T. Richardson
Total citations by year
Citation information
Citations to this article (66)
| Title and authors | Publication | Year |
|---|---|---|
|
Distribution and co-expression patterns of specific cell markers of enteroendocrine cells in pig gastric epithelium
LJ Fothergill, G Galiazzo, B Hunne, MJ Stebbing, J Fakhry, F Weissenborn, TE Coles, JB Furness |
Cell and Tissue Research | 2019 |
|
Yamada' s Textbook of Gastroenterology
DK Podolsky, M Camilleri, JG Fitz, AN Kalloo, F Shanahan, TC Wang |
Yamada' s Textbook of Gastroenterology | 2015 |
|
Comprehensive Physiology
SN Cheuvront, RW Kenefick |
Comprehensive Physiology | 2014 |
|
Handbook of Biologically Active Peptides
DM Pollock |
Handbook of Biologically Active Peptides | 2013 |
|
Physiology of the Gastrointestinal Tract, Two Volume Set
PR Kiela, JF Collins, FK Ghishan |
Physiology of the Gastrointestinal Tract, Two Volume Set | 2012 |
|
A randomized crossover study of the effects of glutamine and lipid on the gastric emptying time of a preoperative carbohydrate drink
S Awad, PE Blackshaw, JW Wright, IA Macdonald, AC Perkins, DN Lobo |
Clinical Nutrition | 2011 |
|
Fetal and Neonatal Physiology
LH Johnson, VK Bhutani |
Fetal and Neonatal Physiology | 2011 |
|
Ghrelin and gastric acid secretion
K Yakabi, J Kawashima, S Kato |
World journal of gastroenterology : WJG | 2008 |
|
Histamine Mediates the Stimulatory Action of Ghrelin on Acid Secretion in Rat Stomach
K Yakabi, S Ro, T Onouhi, T Tanaka, S Ohno, S Miura, Y Johno, K Takayama |
Digestive Diseases and Sciences | 2006 |
|
Physiology of the Gastrointestinal Tract
DJ Drucker |
Physiology of the Gastrointestinal Tract | 2006 |
|
Encyclopedia of Gastroenterology
RA Liddle |
Encyclopedia of Gastroenterology | 2003 |
|
Optimal Treatment of Zollinger-Ellison Syndrome and Related Conditions in Elderly Patients:
P Tomassetti, T Salomone, M Migliori, D Campana, R Corinaldesi |
Drugs & Aging | 2003 |
|
Influence of H. pylori infection on meal-stimulated gastric acid secretion and gastroesophageal acid reflux
M Feldman, B Cryer, D Sammer, E Lee, SJ Spechler |
AJP Gastrointestinal and Liver Physiology | 1999 |
|
Effects of dietary supplements on the availability of minerals in fish meal; preliminary observations
SH Sugiura, FM Dong, RW Hardy |
Aquaculture | 1998 |
|
Peptidergic and cholinergic neurons and mediators in peptone-induced gastroprotection: role of cyclooxygenase-2
K Ehrlich, S Plate, T Stroff, B Gretzer, M Respondek, BM Peskar |
AJP Gastrointestinal and Liver Physiology | 1998 |
|
The G Cell
M Sawada, CJ Dickinson |
Annual Review of Physiology | 1997 |
|
EFFECTS OF ANAESTHETICS AND TRAUMA ON STIMULATED GASTRIC ACID SECRETION IN CHRONIC FISTULA DOGS
SM Bastaki, NG Waton |
Clinical and Experimental Pharmacology and Physiology | 1996 |
|
The influence of food, beverages and NSAIDs on gastric acid secretion and mucosal integrity
WL Peterson |
The Yale journal of biology and medicine | 1996 |
|
Effects of Parenteral Nutrients on Gastrointestinal Motility and Secretion
AA Masclee, HA Gielkens, WF Lam, SY de Boer, CB Lamers |
Scandinavian Journal of Gastroenterology | 1996 |
|
Comparative Evaluation of the Role of Endogenous Gastrin in Basal Acid Secretion in Conscious Rats Provided with Chronic Fistula and Pylorus Ligation
A Nishida, A Uchida-Kobayashi, Y Takemoto, S Akuzawa, K Miyata |
The Japanese Journal of Pharmacology | 1996 |
|
Gastrin receptor genes are expressed in gastric parietal and enterochromaffin-like cells ofMastomys natalensis
M Asahara, Y Kinoshita, H Nakata, Y Matsushima, Y Naribayashi, A Nakamura, T Matsui, K Chihara, J Yamamoto, A Ichikawa, T Chiba |
Digestive Diseases and Sciences | 1994 |
|
Suppression of Helicobacter pylori reduces gastrin releasing peptide stimulated gastrin release in duodenal ulcer patients
K Beardshall, S Moss, J Gill, S Levi, P Ghosh, RJ Playford, J Calam |
Gut | 1992 |
|
Helicobacter pylori -Related Hypergastrinaemia Is Not Due to Elevated Antral Surface pH Studies with Antral Alkalinisation
RS Chittajallu, WD Neithercut, JE Ardill, KE McColl |
Scandinavian Journal of Gastroenterology | 1992 |
|
L-365, 260, a Potent CCK-B/Gastrin Receptor Antagonist, Suppresses Gastric Acid Secretion Induced by Histamine and Bethanechol as Well as Pentagstrin in Rats
A Nishida, H Yuki, R Tsutsumi, K Miyata, T Kamato, H Ito, M Yamano, K Honda |
The Japanese Journal of Pharmacology | 1992 |
|
Mitogenic response of canine fundic epithelial cells in short-term culture to transforming growth factor alpha and insulinlike growth factor I
MC Chen, AT Lee, AH Soll |
Journal of Clinical Investigation | 1991 |
|
Relative Buffering Capacity of Goat Milk, Cow Milk, Soy-Based Infant Formulas, and Commercial Nonprescription Antacid Drugs
YW Park |
Journal of Dairy Science | 1991 |
|
Pharmacology of Peptic Ulcer Disease
MJ Collen, SB Benjamin |
1991 | |
|
Amino acids and amines stimulate gastrin release from canine antral G-cells via different pathways
J DelValle, T Yamada |
Journal of Clinical Investigation | 1990 |
|
Nutritional Regulation of Gastric Secretion, Digestion and Emptying
AG Low |
Nutrition Research Reviews | 1990 |
|
Role of Aggressive Factors in the Pathogenesis of Peptic Ulcer Disease
CT Richardson |
Scandinavian Journal of Gastroenterology | 1990 |
|
Control of Acid Secretion
ML Schubert, RD Shamburek |
Gastroenterology Clinics of North America | 1990 |
|
Gastrin is a major mediator of the gastric phase of acid secretion in dogs: Proof by monoclonal antibody neutralization
TO Kovacs, JH Walsh, V Maxwell, HC Wong, T Azuma, E Katt |
Gastroenterology | 1989 |
|
Bioactivity Studies on New Gastrin Analogues
SE Haugen, AJ Douglas, B Rønning, B Walker, AK Sandvik, RF Murphy, DT Elmore, HL Waldum |
Scandinavian Journal of Gastroenterology | 1989 |
|
Peptic ulceration and phenylketonuria: a possible link?
LG Greeves, DJ Carson, JA Dodge |
Gut | 1988 |
|
Soy protein meals stimulate less gastric acid secretion and gastrin release than beef meals
KE Mcarthur, JH Walsh, CT Richardson |
Gastroenterology | 1988 |
|
Effect of terbutaline, a β2-adrenoreceptor agonist, on gastric acid secretion and serum gastrin concentrations in humans
RC Thirlby, CT Richardson, P Chew, M Feldman |
Gastroenterology | 1988 |
|
Peptic Ulcer Disease in the Pediatric Population
KS Nord |
Pediatric Clinics of North America | 1988 |
|
Detailed comparison of basal and food-stimulated gastric acid secretion rates and serum gastrin concentrations in duodenal ulcer patients and normal subjects
AJ 3rd, M Feldman, C Barnett, JH Walsh, CT Richardson |
Journal of Clinical Investigation | 1987 |
|
Gastrointestinal peptides and insulin secretion
R Ebert, W Creutzfeldt |
Diabetes / Metabolism Reviews | 1987 |
|
Hormones
AW Norman, G Litwack |
Hormone Research | 1987 |
|
Variable Contribution of Gastrin to Gastric Acid Secretion After a Meal in Humans
AJ Blair, CT Richardson, JH Walsh, M Feldman |
Gastroenterology | 1987 |
|
Radioimmunoassay in Basic and Clinical Pharmacology
C Patrono, BA Peskar |
1987 | |
|
Comparison of acid secretory responsiveness to gastrin heptadecapeptide and of gastrin heptadecapeptide pharmacokinetics in duodenal ulcer patients and normal subjects
AJ 3rd, CT Richardson, M Vasko, JH Walsh, M Feldman |
Journal of Clinical Investigation | 1986 |
|
Interaction of the Chemical Senses with Nutrition
CM Christensen |
Interaction of the Chemical Senses with Nutrition | 1986 |
|
Mucosal nerves and smooth muscle relationships with gastric glands of the opossum: An ultrastructural and three-dimensional reconstruction study
LL Seelig, DS Schlusselberg, WK Smith, DJ Woodward |
American Journal of Anatomy | 1985 |
|
Effect of histamine and cimetidine on amino acid meal-stimulated gastrin release at a controlled intragastric pH in healthy human beings
CT Richardson, M Feldman |
Regulatory Peptides | 1985 |
|
Gastrin receptors on isolated canine parietal cells
AH Soll, DA Amirian, LP Thomas, TJ Reedy, JD Elashoff |
Journal of Clinical Investigation | 1984 |
|
Analysis of food stimulation of gastrin release in dogs by a panel of inhibitors
BI Hirschowitz, E Molina |
Peptides | 1984 |
|
Comparative effect of gastrin on hydrogen ion secretion, antroduodenal motility and the interdigestive motility complex (IDMC) in man
CP Dooley, M Miranda, JE Valenzuela |
Digestive Diseases and Sciences | 1984 |
|
Effect of indomethacin on gastric acid and bicarbonate secretion in humans
M Feldman, TJ Colturi |
Gastroenterology | 1984 |
|
Sex-related differences in gastrin release and parietal cell sensitivity to gastrin in healthy human beings
M Feldman, CT Richardson, JH Walsh |
Journal of Clinical Investigation | 1983 |
|
Intravenous infusion of L-isomers of phenylalanine and tryptophan stimulate gastric acid secretion at physiologic plasma concentrations in normal subjects and after parietal cell vagotomy
KE McArthur, JI Isenberg, DL Hogan, SJ Dreier |
Journal of Clinical Investigation | 1983 |
|
Effects of graded amounts of intragastric calcium on acid secretion, gastrin release, and gastric emptying in normal and duodenal ulcer subjects
G Barclay, V Maxwell, MI Grossman, TE Solomon |
Digestive Diseases and Sciences | 1983 |
|
Gastrin release in fistula dogs with solid compared to nutrient and nonnutrient liquid meals
BI Hirschowitz |
Digestive Diseases and Sciences | 1983 |
|
Effect of Gastric Alkalinization on Serum Gastrin Concentrations in Humans
MN Peters, M Feldman, JH Walsh, CT Richardson |
Gastroenterology | 1983 |
|
Gastrointestinal hormones
V Marks, LM Morgan |
Molecular Aspects of Medicine | 1982 |
|
Effect of Individual L-Amino Acids on Gastric Acid Secretion and Serum Gastrin and Pancreatic Polypeptide Release in Humans
IL Taylors, WJ Byrne, DL Christie, ME Ament, JH Walsh |
Gastroenterology | 1982 |
|
Postsecretory Processing of Heptadecapeptide Gastrin: Conversion to C-Terminal Immunoreactive Fragments in the Circulation of the Dog
GJ Dockray, RA Gregory, HJ Tracy, WY Zhu |
Gastroenterology | 1982 |
|
The role of gastrin in duodenal ulcer
JE McGuigan, RF Harty, DG Maico |
Transactions of the American Clinical and Climatological Association | 1981 |
|
Biochemical Aspects of Gastric Secretion
W Rees, L Turnberg |
1981 | |
|
Gastric Acid Secretion is Abnormally Sensitive to Endogenous Gastrin Released after Peptone Test Meals in Duodenal Ulcer Patients
SK Lam, JI Isenberg, MI Grossman, WH Lane, JH Walsh |
Journal of Clinical Investigation | 1980 |
|
Physiology and Pathology of Gastrin
JH Walsh, SK Lam |
1980 | |
|
Effect of Atropine on Vagal Release of Gastrin and Pancreatic Polypeptide
M Feldman, CT Richardson, IL Taylor, JH Walsh |
Journal of Clinical Investigation | 1979 |
|
Abnormal Gastric Function in Longstanding, Insulin-Dependent Diabetic Patients
M Feldman, DB Corbett, EJ Ramsey, JH Walsh, CT Richardson |
Gastroenterology | 1979 |
|
Fasting and Food-stimulated Serum Gastrin Concentrations in Relation to the Antral G-cell Population: A Study in Patients with Peptic Ulcer Disease
R Stave, D Gedde-Dahl, E Gjone |
Scandinavian Journal of Gastroenterology | 1978 |
|
Advances in Metabolic Disorders
G Aurbach, JT Potts |
Advances in Metabolic Disorders | 1964 |
Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)