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Intestinal Assimilation of a Tetrapeptide in the Rat: OBLIGATE FUNCTION OF BRUSH BORDER AMINOPEPTIDASE
Kenneth W. Smithson, Gary M. Gray
Kenneth W. Smithson, Gary M. Gray
Published September 1, 1977
Citation Information: J Clin Invest. 1977;60(3):665-674. https://doi.org/10.1172/JCI108818.
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Intestinal Assimilation of a Tetrapeptide in the Rat: OBLIGATE FUNCTION OF BRUSH BORDER AMINOPEPTIDASE

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Abstract

The small intestine is capable of taking up peptide nutrients of two or three amino acid residues, but the mechanism of intestinal assimilation of larger oligopeptides has not been established. The amino-oligopeptidase of the intestinal brush border possesses high specificity for oligopeptides having bulky side chains and is a candidate for a crucial role in the overall assimilation of dietary protein.

Authors

Kenneth W. Smithson, Gary M. Gray

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