Go to
JCI Insight
Citations to this article
Takashi Kadowaki
Published August 15, 2000
Citation Information: J Clin Invest. 2000;106(4):459-465. https://doi.org/10.1172/JCI10830.
Citation Information: J Clin Invest. 2000;106(4):459-465. https://doi.org/10.1172/JCI10830.
Abstract
Authors
Takashi Kadowaki
Total citations by year
Citation information
Citations to this article (195)
| Title and authors | Publication | Year |
|---|---|---|
|
Blood glucose reduction associated with wholewheat noodle diet in rats with type 2 diabetes mellitus
Wu L, Deng S, Tang C, Chang H, You H, Zhang S, Gao R, Liu C |
Scientific Reports | 2025 |
|
FTO Regulated Intramuscular Fat by Targeting APMAP Gene via an m(6)A-YTHDF2-dependent Manner in Rex Rabbits.
Luo G, Hong T, Yu L, Ren Z |
Cells | 2023 |
|
The Pathogenesis of Diabetes
Guo H, Wu H, Li Z |
International journal of molecular sciences | 2023 |
|
Mechanism of action of Huangbaichen Sanwei formulation in treating T2DM based on network pharmacology and molecular docking
Li C, Shen J, Jing X, Zhang K, Liu L, Wang Y, Zhang H, Sun J |
Medicine | 2023 |
|
Smooth Muscle Insulin Receptor Deletion Causes Voiding Dysfunction: A Mechanism for Diabetic Bladder Dysfunction
Chen H, Wu A, Zeidel ML, Yu W |
Diabetes | 2022 |
|
Importance of Heparan Sulfate Proteoglycans in Pancreatic Islets and β-Cells.
Takahashi I |
International journal of molecular sciences | 2022 |
|
Aloperine Relieves Type 2 Diabetes Mellitus via Enhancing GLUT4 Expression and Translocation
G Song, Y Huang, M Xiong, Z Yang, Q Liu, J Shen, P Zhao, X Yang |
Frontiers in pharmacology | 2021 |
|
RNA sequencing reveals potential interacting networks between the altered transcriptome and ncRNome in the skeletal muscle of diabetic mice
D Kesharwani, A Kumar, M Poojary, V Scaria, M Datta |
Bioscience Reports | 2021 |
|
Role of Heparan Sulfate Proteoglycans in Insulin-producing Pancreatic β-cell Function
I Takahashi |
Trends in Glycoscience and Glycotechnology | 2021 |
|
Effect of water caltrop (Trapa bispinosaRoxb.) pericarp extract on improving insulin resistance in STZ-induced diabetic mice
Y Wang, H Yuan, , T Zeng |
2021 | |
|
Mechanisms of steatosis-derived hepatocarcinogenesis: Lessons from HCV core gene transgenic mice
P Diao, F Jia, X Wang, X Hu, T Kimura, T Nakajima, T Aoyama, K Moriya, K Koike, N Tanaka |
Engineering | 2021 |
|
Expression of MCP-1 in white adipose tissues induce the resistin-hypersecretion in type 2 diabetes
H Hashimoto, T Eto, K Kawai, T Akimoto, K Hioki |
Obesity Medicine | 2020 |
|
Beneficial effects of Aronia melanocarpa berry extract on hepatic insulin resistance in type 2 diabetes mellitus rats: Hypoglycemic effect of A. melanocarpa…
J Mu, G Xin, B Zhang, Y Wang, C Ning, X Meng |
Journal of Food Science | 2020 |
|
Molecular networks in Network Medicine: Development and applications
EK Silverman, HH Schmidt, E Anastasiadou, L Altucci, M Angelini, L Badimon, JL Balligand, G Benincasa, G Capasso, F Conte, AD Costanzo, L Farina, G Fiscon, L Gatto, M Gentili, J Loscalzo, C Marchese, C Napoli, P Paci, M Petti, J Quackenbush, P Tieri, D Viggiano, G Vilahur, K Glass, J Baumbach |
Wiley interdisciplinary reviews. Systems biology and medicine | 2020 |
|
Safety and Mode of Action of Diabetes Medications in comparison with 5-Aminolevulinic Acid (5-ALA)
PR Rehani, H Iftikhar, M Nakajima, T Tanaka, Z Jabbar, RN Rehani |
Journal of Diabetes Research | 2019 |
|
Effects and mechanisms of iridoid glycosides from Patrinia scabiosaefolia on improving insulin resistance in 3T3-L1 adipocytes
Z Liu, L Xu, X Xu, Y Niu, FS Saadeldeen, W Kang |
Food and Chemical Toxicology | 2019 |
|
Insulin/IGF-1 Drives PERIOD Synthesis to Entrain Circadian Rhythms with Feeding Time
P Crosby, R Hamnett, M Putker, NP Hoyle, M Reed, CJ Karam, ES Maywood, A Stangherlin, JE Chesham, EA Hayter, L Rosenbrier-Ribeiro, P Newham, H Clevers, DA Bechtold, JS ONeill |
Cell | 2019 |
|
Genomic Profile of rIR and rIRR in Type 2 Diabetes Mellitus Rat Model toward Effect of Goat Milk CSN1S2 Protein
SH Tambunan, HN Meidinna, RN Rohmah, F Fatchiyah |
Journal of physics. Conference series | 2019 |
|
Antidiabetic Effects of Soluble Dietary Fiber from Steam Explosion-Modified Black Soybean Hull in Low-Dose Streptozotocin-Induced Type 2 Diabetic Mouses
M Shen, W Wang, Y Ge, Z Kang, J Wang, Z Quan, J Xiao, L Cao |
Journal of Chemistry | 2019 |
|
Blind fish
A Ojha, M Watve |
Evolution, Medicine, and Public Health | 2018 |
|
Inferring causal pathways among three or more variables from steady-state correlations in a homeostatic system
S Chawla, A Pund, V B., S Kulkarni, M Diwekar-Joshi, M Watve, M Ruscica |
PloS one | 2018 |
|
Utilizing Confocal Microscopy to Characterize Human and Mouse Adipose Tissue
CP Blackshear, MR Borrelli, EZ Shen, RC Ransom, NN Chung, SM Vistnes, D Irizarry, R Nazerali, A Momeni, MT Longaker, DC Wan |
Tissue Engineering Part C: Methods | 2018 |
|
Characterization of glucose-stimulated insulin release protocols in african green monkeys ( Chlorocebus aethiops)
S Liddie, H Okamoto, J Gromada, M Lawrence |
Journal of Medical Primatology | 2018 |
|
IRS-2 Partially Compensates for the Insulin Signal Defects in IRS-1−/− Mice Mediated by miR-33
CY Tang, XF Man, Y Guo, HN Tang, J Tang, CL Zhou, SW Tan, M Wang, HD Zhou |
Molecules and Cells | 2017 |
|
Maternal bisphenol A exposure alters rat offspring hepatic and skeletal muscle insulin signaling protein abundance
KD Galyon, F Farshidi, G Han, MG Ross, M Desai, JK Jellyman |
American Journal of Obstetrics and Gynecology | 2017 |
|
Quercetin, a Lead Compound against Type 2 Diabetes Ameliorates Glucose Uptake via AMPK Pathway in Skeletal Muscle Cell Line
RD R, AD Arya, P Nisha, PJ P |
Frontiers in pharmacology | 2017 |
|
Animal models for assessing the impact of natural products on the aetiology and metabolic pathophysiology of Type 2 diabetes
M Asrafuzzaman, Y Cao, R Afroz, D Kamato, S Gray, PJ Little |
Biomedicine & Pharmacotherapy | 2017 |
|
Imbalanced Insulin Actions in Obesity and Type 2 Diabetes: Key Mouse Models of Insulin Signaling Pathway
T Kubota, N Kubota, T Kadowaki |
Cell Metabolism | 2017 |
|
Umbilical cord mesenchymal stem cells are able to undergo differentiation into functional islet-like cells in type 2 diabetic tree shrews
XH Pan, X Huang, GP Ruan, RQ Pang, Q Chen, JX Wang, J He, J Zhao, XM Cai, N Zhao, Y Chen, XQ Zhu |
Molecular and Cellular Probes | 2017 |
|
The Association Between IGF-I and IGFBP-3 and Incident Diabetes in an Older Population of Men and Women in the Cardiovascular Health Study
CS Aneke-Nash, X Xue, Q Qi, ML Biggs, A Cappola, L Kuller, M Pollak, BM Psaty, D Siscovick, K Mukamal, HD Strickler, RC Kaplan |
The Journal of clinical endocrinology and metabolism | 2017 |
|
Geniposide promotes autophagy to inhibit insulin resistance in HepG2 cells via P62/NF-κB/GLUT-4
H Jiang, Y Ma, J Yan, J Liu, L Li |
Molecular medicine reports | 2017 |
|
What to expect from an evolutionary hypothesis for a human disease: The case of type 2 diabetes
M Watve, M Diwekar-Joshi |
HOMO - Journal of Comparative Human Biology | 2016 |
|
Application of network construction to estimate functional changes to insulin receptor substrates?1 and?2 in Huh7 cells following infection with the hepatitis?C virus
J Liu, L Wang, W Wang, Y Li, X Jia, S Zhai, J Shi, S Dang |
Molecular medicine reports | 2016 |
|
Adipose- and muscle-derived Wnts trigger pancreatic β-cell adaptation to systemic insulin resistance
K Kozinski, M Jazurek, P Dobrzyn, J Janikiewicz, K Kolczynska, A Gajda, A Dobrzyn |
Scientific Reports | 2016 |
|
Hypothalamic AMP-Activated Protein Kinase Regulates Biphasic Insulin Secretion from Pancreatic β Cells during Fasting and in Type 2 Diabetes
S Kume, M Kondo, S Maeda, Y Nishio, T Yanagimachi, Y Fujita, M Haneda, K Kondo, A Sekine, S Araki, H Araki, M Chin-Kanasaki, S Ugi, D Koya, S Kitahara, K Maeda, A Kashiwagi, T Uzu, H Maegawa |
EBioMedicine | 2016 |
|
Importance of Lean Muscle Maintenance to Improve Insulin Resistance by Body Weight Reduction in Female Patients with Obesity
Y Fukushima, S Kurose, H Shinno, HC Thu, N Takao, H Tsutsumi, Y Kimura |
Diabetes & Metabolism Journal | 2016 |
|
Acupuncture Alters Expression of Insulin Signaling Related Molecules and Improves Insulin Resistance in OLETF Rats
XY Huang, L Zhang, J Sun, NG Xu, W Yi |
Evidence-Based Complementary and Alternative Medicine | 2016 |
|
Identification of a Novel Function of Adipocyte Plasma Membrane-Associated Protein (APMAP) in Gestational Diabetes Mellitus by Proteomic Analysis of Omental Adipose Tissue
Y Ma, J Gao, J Yin, L Gu, X Liu, S Chen, Q Huang, H Lu, Y Yang, H Zhou, Y Wang, Y Peng |
Journal of Proteome Research | 2016 |
|
Principles of Diabetes Mellitus
A Ohri, S Vergano, R Bhambri, SH Schneider |
Principles of Diabetes Mellitus | 2016 |
|
Elucidation of Pathogenesis and Development of Therapeutic Strategy of Type 2 Diabetes-progress in the Thirty Years
T Kadowaki |
Nihon Naika Gakkai Zasshi | 2016 |
|
Elucidation of Pathogenesis and Development of Therapeutic Strategy of Type 2 Diabetes -Progress in the Thirty Years
T Kadowaki |
Nihon Naika Gakkai Zasshi | 2016 |
|
A Novel Peroxisome Proliferator-activated Receptor (PPAR)α Agonist and PPARγ Antagonist, Z-551, Ameliorates High-fat Diet-induced Obesity and Metabolic Disorders in Mice
Y Shiomi, T Yamauchi, M Iwabu, M Okada-Iwabu, R Nakayama, Y Orikawa, Y Yoshioka, K Tanaka, K Ueki, T Kadowaki |
The Journal of biological chemistry | 2015 |
|
Hot water extracts of edible Chrysanthemum morifolium Ramat. exert antidiabetic effects in obese diabetic KK-A y mice
J Yamamoto, M Tadaishi, T Yamane, Y Oishi, M Shimizu, K Kobayashi-Hattori |
Bioscience Biotechnology and Biochemistry | 2015 |
|
International Textbook of Diabetes Mellitus: DeFronzo/International Textbook of Diabetes Mellitus, Fourth Edition
RN Bergman, M Ader |
International Textbook of Diabetes Mellitus: DeFronzo/International Textbook of Diabetes Mellitus, Fourth Edition | 2015 |
|
Profound hyperglycemia in knockout mutant mice identifies novel function for POU4F2/Brn-3b in regulating metabolic processes
S Bitsi, H Ali, L Maskell, S Ounzain, V Mohamed-Ali, VS Budhram-Mahadeo |
American journal of physiology. Endocrinology and metabolism | 2015 |
|
Chronic ethanol treatment of human hepatocytes inhibits the activation of the insulin signaling pathway by increasing cytosolic free calcium levels
YM Chen, JF Zhao, YL Liu, J Chen, RL Jiang |
International journal of molecular medicine | 2015 |
|
Tissue-specific insulin signaling in the regulation of metabolism and aging: Insulin Signaling in Metabolism and Aging
J Zhang, F Liu |
IUBMB Life | 2014 |
|
Insulin Receptor Substrate-2 (Irs2) in Endothelial Cells Plays a Crucial Role in Insulin Secretion
S Hashimoto, N Kubota, H Sato, M Sasaki, I Takamoto, T Kubota, K Nakaya, M Noda, K Ueki, T Kadowaki |
Diabetes | 2014 |
|
Antidiabetic Effect of Methanolic Extract from Berberis julianae Schneid. via Activation of AMP-Activated Protein Kinase in Type 2 Diabetic Mice
J Yang, P Zhao, D Wan, Q Zhou, C Wang, G Shu, Z Mei, X Yang |
Evidence-Based Complementary and Alternative Medicine | 2014 |
|
Humanin and Age-Related Diseases: A New Link?
Z Gong, E Tas, R Muzumdar |
Frontiers in Endocrinology | 2014 |
|
microRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes
CL Kurtz, BC Peck, EE Fannin, C Beysen, J Miao, SR Landstreet, S Ding, V Turaga, PK Lund, S Turner, SB Biddinger, KC Vickers, P Sethupathy |
Diabetes | 2014 |
|
Organophosphorus insecticide, monocrotophos, possesses the propensity to induce insulin resistance in rats on chronic exposure: Monocrotophos induces insulin resistance in rats
R Nagaraju, AK Joshi, PS Rajini |
Journal of Diabetes | 2014 |
|
Adiponectin and its receptors: implications for obesity-associated diseases and longevity
T Kadowaki, T Yamauchi, M Okada-Iwabu, M Iwabu |
The Lancet Diabetes & Endocrinology | 2014 |
|
Long-term models of oxidative stress and mitochondrial damage in insulin resistance progression
EJ Graham, FR Adler |
Journal of Theoretical Biology | 2014 |
|
Optimal therapy of type 2 diabetes: a controversial challenge
A Dardano, G Penno, SD Prato, R Miccoli |
Aging | 2014 |
|
The herbal composition GGEx18 from Laminaria japonica, Rheum palmatum , and Ephedra sinica inhibits visceral obesity and insulin resistance by upregulating visceral adipose genes involved in fatty acid oxidation
J Oh, H Lee, H Lim, S Woo, SS Shin, M Yoon |
Pharmaceutical Biology | 2014 |
|
Experimental primates and non-human primate (NHP) models of human diseases in China: current status and progress
Xiao-Liang ZHANG, Wei PANG, Xin-Tian HU, Jia-Li LI, Yong-Gang YAO, Yong-Tang ZHENG |
Zoological Research | 2014 |
|
TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass
I Takamoto, N Kubota, K Nakaya, K Kumagai, S Hashimoto, T Kubota, M Inoue, E Kajiwara, H Katsuyama, A Obata, Y Sakurai, M Iwamoto, T Kitamura, K Ueki, T Kadowaki |
Diabetologia | 2013 |
|
Abnormalities in carbohydrate and lipid metabolisms in high-fructose dietfed insulin-resistant rats: amelioration by Catharanthus roseus treatments
K Rasineni, R Bellamkonda, SR Singareddy, S Desireddy |
Journal of Physiology and Biochemistry | 2013 |
|
Daily Rice Intake Strongly Influences the Incidence of Metabolic Syndrome in Japanese Men Aged 40-59 Years
Y Watanabe, I Saito, Y Asada, T Kishida, T Matsuo, M Yamaizumi, T Kato |
Journal of Rural Medicine | 2013 |
|
Beneficial effects of Chlorella on glucose and lipid metabolism in obese rodents on a high-fat diet
N Noguchi, F Konishi, S Kumamoto, I Maruyama, Y Ando, T Yanagita |
Obesity Research & Clinical Practice | 2013 |
|
UP780, a Chromone-Enriched Aloe Composition Improves Insulin Sensitivity
M Yimam, J Zhao, B Corneliusen, M Pantier, LA Brownell, Q Jia |
Metabolic Syndrome and Related Disorders | 2013 |
|
Methods and models for metabolic assessment in mice
G Pacini, B Omar, B Ahrén |
Journal of Diabetes Research | 2013 |
|
Role of insulin resistance in the pathogenesis and development of type 2 diabetes in WBN/Kob-Lepr(fa) rats
A Okuno, N Kaji, A Takahashi, D Nagakubo, K Ohno-Ichiki, M Shirai, F Asai |
Journal of Veterinary Medical Science | 2013 |
|
Biochemical adaptations of mammalian hibernation: exploring squirrels as a perspective model for naturally induced reversible insulin resistance
CW Wu, KK Biggar, KB Storey |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] | 2013 |
|
Pancreatic Function, Type 2 Diabetes, and Metabolism in Aging
Z Gong, RH Muzumdar |
International Journal of Endocrinology | 2012 |
|
Mechanisms of Dietary Response in Mice and Primates: A Role for EGR1 in Regulating the Reaction to Human-Specific Nutritional Content
K Weng, H Hu, AG Xu, P Khaitovich, M Somel |
PloS one | 2012 |
|
Human-Specific SNP in Obesity Genes, Adrenergic Receptor Beta2 (ADRB2), Beta3 (ADRB3), and PPAR γ2 (PPARG), during Primate Evolution
A Takenaka, S Nakamura, F Mitsunaga, M Inoue-Murayama, T Udono, B Suryobroto |
PloS one | 2012 |
|
Guava leaf extracts alleviate fatty liver via expression of adiponectin receptors in SHRSP.Z-Leprfa/Izm rats
H Yoshitomi, X Guo, T Liu, M Gao |
Nutrition & Metabolism | 2012 |
|
Calorie Restriction from a Young Age Preserves the Functions of Pancreatic ^|^beta; Cells in Aging Rats
X He, X Zhao, Q Gu, J Shen, Y Hu, R Hu |
The Tohoku Journal of Experimental Medicine | 2012 |
|
Anti-diabetic effect of sorghum extract on hepatic gluconeogenesis of streptozotocin-induced diabetic rats
J Kim, Y Park |
Nutrition & Metabolism | 2012 |
|
Pollen Typhae total flavone improves insulin-induced glucose uptake through the β-arrestin-2-mediated signaling in C2C12 myotubes
XT Feng, TZ Wang, YI CHEN, JB Liu, YI LIU, WJ Wang |
International journal of molecular medicine | 2012 |
|
Doves, Diplomats, and Diabetes
M Watve |
2012 | |
|
Pioglitazone pretreated human mesenchymal stem cells improved cardiomyogenic efficiency and cardiac function in vivo
Daisuke Shinmura, Shunichiro Miyoshi, Ikuko Togashi, Nobuhiro Nishiyama, Naoko Hida, Hiroko Tsuji, Hikaru Nakamizo, Kaoru Segawa, Yuiko Tsukada, Satoshi Ogawa, Akihiro Umezawa |
Stem Cells | 2011 |
|
Tissue specificity on insulin action and resistance: past to recent mechanisms
M Benito |
Acta Physiologica | 2011 |
|
Effectiveness of rosiglitazone on bleomycin-induced lung fibrosis: Assessed by micro-computed tomography and pathologic scores
GY Jin, SM Bok, YM Han, MJ Chung, KH Yoon, SR Kim, YC Lee |
European Journal of Radiology | 2011 |
|
Insulin resistance and deficiency of post-receptor signal transduction after severe burns
B PAN, F CHANG, W LU |
Academic Journal of Second Military Medical University | 2011 |
|
Oral hypoglycaemic, antihyperglycaemic and antidiabetic activities of Sri Lankan Broken Orange Pekoe Fannings (BOPF) grade black tea (Camellia sinensis L.) in rats
KR Abeywickrama, WD Ratnasooriya, AM Amarakoon |
Journal of Ethnopharmacology | 2011 |
|
Tissue-specificity of insulin action and resistance*
M Benito |
Archives Of Physiology And Biochemistry | 2011 |
|
Improvement of insulin resistance by Cyanidin 3-glucoside, anthocyanin from black beans through the up-regulation of GLUT4 gene expression
T Inaguma, J Han, H Isoda |
BMC proceedings | 2011 |
|
4. Molecular Mechanism and Treatment Strategy of Type 2 Diabetes
T Kadowaki |
Nihon Naika Gakkai Zasshi | 2011 |
|
1. Obesity and Diabetes
T Kadowaki |
Nihon Naika Gakkai Zasshi | 2011 |
|
Differential sensitivity to adrenergic stimulation underlies the sexual dimorphism in the development of diabetes caused by Irs-2 deficiency
MJ Garcia-Barrado, MC Iglesias-Osma, V Moreno-Viedma, MF Mansilla, SS Gonzalez, J Carretero, J Moratinos, DJ Burks |
Biochemical Pharmacology | 2011 |
|
Role of Reactive Oxygen Species in the Progression of Type 2 Diabetes and Atherosclerosis
H Kaneto, N Katakami, M Matsuhisa, T Matsuoka |
Mediators of Inflammation | 2010 |
|
The Renin-Angiotensin System: Current Research Progress in The Pancreas
PS Leung |
2010 | |
|
The Renin-Angiotensin System: Current Research Progress in The Pancreas
PS Leung |
2010 | |
|
The Renin-Angiotensin System: Current Research Progress in The Pancreas
PS Leung |
2010 | |
|
The Renin-Angiotensin System: Current Research Progress in The Pancreas
PS Leung |
2010 | |
|
The Renin-Angiotensin System: Current Research Progress in The Pancreas
PS Leung |
2010 | |
|
The Renin-Angiotensin System: Current Research Progress in The Pancreas
PS Leung |
2010 | |
|
The Renin-Angiotensin System: Current Research Progress in The Pancreas
PS Leung |
2010 | |
|
The Renin-Angiotensin System: Current Research Progress in The Pancreas
PS Leung |
2010 | |
|
Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues
T Uemura, S Hirai, N Mizoguchi, T Goto, JY Lee, K Taketani, Y Nakano, J Shono, S Hoshino, N Tsuge, T Narukami, N Takahashi, T Kawada |
Molecular Nutrition & Food Research | 2010 |
|
Insulin resistance at the crossroads of metabolic syndrome: Systemic analysis using microarrays
E Kim |
Biotechnology Journal | 2010 |
|
Prevention of High Fat Diet Induced Insulin Resistance in C57BL/6J Mice by Sida rhomboidea ROXB. Extract
Menaka Chanu Thounaojam, Ravirajsinh Navalsinh Jadeja, Ansarullah, Ranjitsinh Vijaysinh Devkar, A. V. Ramachandran |
JOURNAL OF HEALTH SCIENCE | 2010 |
|
Relating smoking, obesity, insulin resistance and ovarian biomarker changes to the final menstrual period (FMP)
MF Sowers, D McConnell, M Yosef, ML Jannausch, SD Harlow, JF Randolph |
Annals of the New York Academy of Sciences | 2010 |
|
2) Treatment Strategies for Preventing Atherosclerosis in Patients with Diabetes Mellitus
T Kadowaki |
Nihon Naika Gakkai Zasshi | 2010 |
|
Type 2 Diabetes
C Stocker |
2009 | |
|
Type 2 Diabetes
C Stocker |
2009 | |
|
Type 2 Diabetes
C Stocker |
2009 | |
|
Type 2 Diabetes
C Stocker |
2009 | |
|
Type 2 Diabetes
C Stocker |
2009 | |
|
Emerging Concepts in the Pathophysiology of Type 2 Diabetes Mellitus
PN Surampudi, J John-Kalarickal, VA Fonseca |
Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine | 2009 |
|
Fenofibrate inhibits adipocyte hypertrophy and insulin resistance by activating adipose PPARα in high fat diet-induced obese mice
S Jeong, M Yoon |
Experimental and Molecular Medicine | 2009 |
|
Molecular cloning and characterization of olive flounder (Paralichthys olivaceus) peroxisome proliferator-activated receptor γ
HK Cho, HJ Kong, BH Nam, WJ Kim, JK Noh, JH Lee, YO Kim, JH Cheong |
General and Comparative Endocrinology | 2009 |
|
The susceptibility of three strains of Chinese minipigs to diet-induced type 2 diabetes mellitus
H Chen, Y Liu, C Li, X Guo, L Huang |
Lab Animal | 2009 |
|
4. Recent Topics of the Mechanism and Treatment of Diabetes Mellitus
T Kadowaki |
Nihon Naika Gakkai Zasshi | 2009 |
|
Metabolic effects of dietary cholesterol in an animal model of insulin resistance and hepatic steatosis
H Basciano, AE Miller, M Naples, C Baker, R Kohen, E Xu, Q Su, EM Allister, MB Wheeler, K Adeli |
American journal of physiology. Endocrinology and metabolism | 2009 |
|
Crucial role of insulin receptor substrate-2 in compensatory β-cell hyperplasia in response to high fat diet-induced insulin resistance
I Takamoto, Y Terauchi, N Kubota, M Ohsugi, K Ueki, T Kadowaki |
Diabetes, Obesity and Metabolism | 2008 |
|
Mechanisms of macrophage activation in obesity-induced insulin resistance
JI Odegaard, A Chawla |
Nature Clinical Practice Endocrinology & Metabolism | 2008 |
|
Transgenic expression of a mutated cyclin-dependent kinase 4 (CDK4/R24C) in pancreatic β-cells prevents progression of diabetes in db/db mice
K Miyawaki, H Inoue, P Keshavarz, K Mizuta, A Sato, Y Sakamoto, M Moritani, K Kunika, T Tanahashi, M Itakura |
Diabetes Research and Clinical Practice | 2008 |
|
Reply
J Bommer, T Heinrich, H Heidt, V Hafner, E Jenetzky, I Walter-Sack, G Mikus |
Nephrology Dialysis Transplantation | 2008 |
|
The Protective Effect of Yi-Qi-Yang-Yin-Ye, a Compound of Traditional Chinese Herbal Medicine in Diet-Induced Obese Rats
GW He, WJ Qu, B Fan, R Jing, R He |
The American journal of Chinese medicine | 2008 |
|
Signal Transduction in the Cardiovascular System in Health and Disease
AK Srivastava, MB Anand-Srivastava |
2008 | |
|
Genomics in Endocrinology
S Handwerger, B Aronow |
2008 | |
|
Obesity: Genomics and Postgenomics
A Xu, A Butler, G Barsh |
Obesity: Genomics and Postgenomics | 2007 |
|
Quantitative Profile of Five Murine Core Proteomes Using Label-free Functional Proteomics
PR Cutillas, B Vanhaesebroeck |
Molecular & cellular proteomics : MCP | 2007 |
|
Differential Mitogenic Signaling in Insulin Receptor-Deficient Fetal Pancreatic β-Cells
C Guillen, P Navarro, M Robledo, AM Valverde, M Benito |
Endocrinology | 2006 |
|
Molecular backgrounds of age-related osteoporosis from mouse genetics approaches
H Kawaguchi |
Reviews in Endocrine and Metabolic Disorders | 2006 |
|
The Novel Roles of Liver for Compensation of Insulin Resistance in Human Growth Hormone Transgenic Rats
Y Cho, M Ariga, Y Uchijima, K Kimura, JY Rho, Y Furuhata, F Hakuno, K Yamanouchi, M Nishihara, SI Takahashi |
Endocrinology | 2006 |
|
Treating the metabolic syndrome using angiotensin receptor antagonists that selectively modulate peroxisome proliferator-activated receptor-γ
HA Pershadsingh |
The International Journal of Biochemistry & Cell Biology | 2006 |
|
Lipid and lipoprotein dysregulation in insulin resistant states
RK Avramoglu, H Basciano, K Adeli |
Clinica Chimica Acta | 2006 |
|
Glucose-lowering effect of powder formulation of African black tea extract in KK-Ay/TaJcl diabetic mouse
Y Shoji, H Nakashima |
Archives of Pharmacal Research | 2006 |
|
Regulation of Sarcolemmal Transport of Substrates in the Healthy and Diseased Heart
JF Glatz, A Bonen, DM Ouwens, JJ Luiken |
Cardiovascular Drugs and Therapy | 2006 |
|
Insulin Resistance Is an Intrinsic Defect Independent of Fat Mass in Women with Turner’s Syndrome
B Salgin, R Amin, K Yuen, RM Williams, P Murgatroyd, DB Dunger |
Hormone Research | 2006 |
|
Effects of glimepiride and glyburide on glucose counterregulation and recovery from hypoglycemia
E Szoke, NR Gosmanov, JC Sinkin, A Nihalani, AB Fender, PE Cryer, C Meyer, JE Gerich |
Metabolism | 2006 |
|
Transient suppression of PPARγ directed ES cells into an osteoblastic lineage
A Yamashita, T Takada, K Nemoto, G Yamamoto, R Torii |
FEBS Letters | 2006 |
|
Promoter characterization and transcriptional regulation of Ncb5or, a novel reductase necessary for pancreatic β-cell maintenance
K Larade, HF Bunn |
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression | 2006 |
|
Rosiglitazone Reduces the Evolution of Experimental Periodontitis in the Rat
RD Paola, E Mazzon, D Maiere, D Zito, D Britti, MD Majo, T Genovese, S Cuzzocrea |
Journal of dental research | 2006 |
|
Modelos experimentais de resistência à insulina e obesidade: lições aprendidas
ML Cesaretti, O Kohlmann |
Arquivos brasileiros de endocrinologia e metabologia | 2006 |
|
Peroxisome Proliferator-activated Receptor γ-mediated Regulation of Neural Stem Cell Proliferation and Differentiation
K Wada, A Nakajima, K Katayama, C Kudo, A Shibuya, N Kubota, Y Terauchi, M Tachibana, H Miyoshi, Y Kamisaki, T Mayumi, T Kadowaki, RS Blumberg |
The Journal of biological chemistry | 2006 |
|
The Diabetic Kidney
P Cortes, CE Mogensen |
2006 | |
|
Muscle-specific deletion of the Glut4 glucose transporter alters multiple regulatory steps in glycogen metabolism
YB Kim, OD Peroni, WG Aschenbach, Y Minokoshi, K Kotani, A Zisman, CR Kahn, LJ Goodyear, BB Kahn |
Molecular and cellular biology | 2005 |
|
The cyclopentenone prostaglandin 15-deoxyΔ12,14-prostaglandin J2 attenuates the development of zymosan-induced shock
S Marzocco, RD Paola, E Mazzon, T Genovese, D Britti, A Pinto, G Autore, S Cuzzocrea |
Intensive Care Medicine | 2005 |
|
Functional role of RXRs and PPARgamma in mature adipocytes
D Metzger, T Imai, M Jiang, R Takukawa, B Desvergne, W Wahli, P Chambon |
Prostaglandins, leukotrienes, and essential fatty acids | 2005 |
|
Distinct effects of PPARgamma insufficiency on bone marrow cells, osteoblasts, and osteoclastic cells
H Kawaguchi, T Akune, M Yamaguchi, S Ohba, N Ogata, U Chung, N Kubota, Y Terauchi, T Kadowaki, K Nakamura |
Journal of Bone and Mineral Metabolism | 2005 |
|
Atherosclerosis: Diet and Drugs
A von Eckardstein |
2005 | |
|
Insulin receptor substrate-2 plays a crucial role in b cells and the hypothalamus
Naoto Kubota, Yasuo Terauchi, Kazuyuki Tobe, Wataru Yano, Ryo Suzuki, Kohjiro Ueki, Iseki Takamoto, Hidemi Satoh, Toshiyuki Maki, Tetsuya Kubota, Masao Moroi, Miki Okada-Iwabu, Osamu Ezaki, Ryozo Nagai, Yoichi Ueta, Takashi Kadowaki, and Tetsuo Noda |
Journal of Clinical Investigation | 2004 |
|
PPAR-gamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors
Toru Akune, Shinsuke Ohba, Satoru Kamekura, Masayuki Yamaguchi, Ung-il Chung, Naoto Kubota, Yasuo Terauchi, Yoshifumi Harada, Yoshiaki Azuma, Kozo Nakamura, Takashi Kadowaki, Hiroshi Kawaguchi |
Journal of Clinical Investigation | 2004 |
|
Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3
T Kawaguchi, T Yoshida, M Harada, T Hisamoto, Y Nagao, T Ide, E Taniguchi, H Kumemura, S Hanada, M Maeyama, S Baba, H Koga, R Kumashiro, T Ueno, H Ogata, A Yoshimura, M Sata |
The American Journal of Pathology | 2004 |
|
New Insights into the Integrated Physiology of Insulin Action
Y Kitamura, D Accili |
Reviews in Endocrine and Metabolic Disorders | 2004 |
|
Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse
T Imai, R Takakuwa, S Marchand, E Dentz, JM Bornert, N Messaddeq, O Wendling, M Mark, B Desvergne, W Wahli, P Chambon, D Metzger |
Proceedings of the National Academy of Sciences | 2004 |
|
Glucose Homeostasis and Tissue Transcript Content of Insulin Signaling Intermediates in Four Inbred Strains of Mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1
HJ Goren, RN Kulkarni, CR Kahn |
Endocrinology | 2004 |
|
Chemistry and Biochemistry of Type 2 Diabetes
SA Ross, EA Gulve, M Wang |
Chemical Reviews | 2004 |
|
PPAR-gamma expression modulates insulin sensitivity in C2C12 skeletal muscle cells
NK Verma, J Singh, CS Dey |
British Journal of Pharmacology | 2004 |
|
Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance
Y Shintani, H Fujie, H Miyoshi, T Tsutsumi, K Tsukamoto, S Kimura, K Moriya, K Koike |
Gastroenterology | 2004 |
|
Age-related changes of insulin receptors, plasma insulin and glucose level
G Korićanac, M Vulović, S Radivojša, Z Žakula, N Ribarac-Stepić |
Biogerontology | 2004 |
|
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-γ, reduces acute inflammation
S Cuzzocrea, B Pisano, L Dugo, A Ianaro, P Maffia, NS Patel, RD Paola, A Ialenti, T Genovese, PK Chatterjee, MD Rosa, AP Caputi, C Thiemermann |
European Journal of Pharmacology | 2004 |
|
Protective effect of endogenous PPARγ against acute gastric mucosal lesions associated with ischemia-reperfusion
K Wada, A Nakajima, H Takahashi, M Yoneda, N Fujisawa, E Ohsawa, T Kadowaki, N Kubota, Y Terauchi, N Matsuhashi, LJ Saubermann, N Nakajima, RS Blumberg |
AJP Gastrointestinal and Liver Physiology | 2004 |
|
Cardiovascular Pharmacogenetics
MR Wilkins |
2004 | |
|
Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma
DB Savage, GD Tan, CL Acerini, SA Jebb, M Agostini, M Gurnell, RL Williams, AM Umpleby, EL Thomas, JD Bell, AK Dixon, F Dunne, R Boiani, S Cinti, A Vidal-Puig, F Karpe, VK Chatterjee, S O'Rahilly |
Diabetes | 2003 |
|
International Textbook of Diabetes Mellitus
RA DeFronzo, L Mandarino, E Ferrannini |
International Textbook of Diabetes Mellitus | 2003 |
|
ThePro12Ala PPAR?2 gene missense mutation is associated with obesity and insulin resistance in Swedish middle-aged men
R Rosmond, M Chagnon, C Bouchard |
Diabetes/Metabolism Research and Reviews | 2003 |
|
Role of PPAR.GAMMA. in the development of the central nervous system
K WADA, Y KAMISAKI |
Folia Pharmacologica Japonica | 2003 |
|
Adolescent onset Type 2 diabetes in a non-obese Caucasian patient with an unbalanced translocation
KR Owen, J Roland, K Smith, AT Hattersley |
Diabetic Medicine | 2003 |
|
Reduction in the evolution of murine type II collagen-induced arthritis by treatment with rosiglitazone, a ligand of the peroxisome proliferator-activated receptor gamma
S Cuzzocrea, E Mazzon, L Dugo, NS Patel, I Serraino, RD Paola, T Genovese, D Britti, MD Maio, AP Caputi, C Thiemermann |
Arthritis & Rheumatism | 2003 |
|
Mechanisms for the deterioration in glucose tolerance associated with HIV protease inhibitor regimens
HJ Woerle, PR Mariuz, C Meyer, RC Reichman, EM Popa, JM Dostou, SL Welle, JE Gerich |
Diabetes | 2003 |
|
Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes
Angela M Valverde, Deborah J Burks, Isabel Fabregat, Tracey L Fisher, José Carretero, Morris F White, Manuel Benito |
Diabetes | 2003 |
|
Complex haplotypes of IRS2 gene are associated with severe obesity and reveal heterogeneity in the effect of Gly1057Asp mutation
C Lautier, SA Mkadem, E Renard, JF Brun, JC Gris, J Bringer, F Grigorescu |
Human Genetics | 2003 |
|
Suppression of body fat accumulation in myostatin deficient mice
Alexandra C. McPherron, Se-Jin Lee |
Journal of Clinical Investigation | 2002 |
|
Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1
J Nakae, WH Biggs, T Kitamura, WK Cavenee, CV Wright, KC Arden, D Accili |
Nature Genetics | 2002 |
|
PPAR agonists in health and disease: a pathophysiologic and clinical overview
S Mudaliar, RR Henry |
Current Opinion in Endocrinology & Diabetes | 2002 |
|
Gene and Cell Therapies for Diabetes Mellitus
N Giannoukakis, PD Robbins |
BioDrugs | 2002 |
|
Insights into Molecular Pathogenesis of Type 2 Diabetes from Knockout Mouse Models
Y Terauchi, T Kadowaki |
Endocrine Journal | 2002 |
|
Fasting plasma free fatty acid concentrations and Pro12Ala polymorphism of the peroxisome proliferator-activated receptor (PPAR) gamma2 gene in healthy individuals
O Vaccaro, FP Mancini, G Ruffa, L Sabatino, C Iovine, M Masulli, V Colantuoni, G Riccardi |
Clinical Endocrinology | 2002 |
|
PPARγ ligands inhibit nitrotyrosine formation and inflammatory mediator expressions in adjuvant-induced rheumatoid arthritis mice
T Shiojiri, K Wada, A Nakajima, K Katayama, A Shibuya, C Kudo, T Kadowaki, T Mayumi, Y Yura, Y Kamisaki |
European Journal of Pharmacology | 2002 |
|
Differential regulation of gene expression and insulin-induced activation of phosphodiesterase 3B in adipocytes of lean insulin-resistant IRS-1 (−/−) mice
M Hasegawa, Y Tang, H Osawa, H Onuma, T Nishimiya, M Ochi, Y Terauchi, T Kadowaki, H Makino |
Diabetes Research and Clinical Practice | 2002 |
|
Hexosamines as mediators of nutrient sensing and regulation in diabetes
DA McClain |
Journal of Diabetes and its Complications | 2002 |
|
Gene Expression Profile in Skeletal Muscle of Type 2 Diabetes and the Effect of Insulin Treatment
R Sreekumar, P Halvatsiotis, JC Schimke, KS Nair |
Diabetes | 2002 |
|
Variations in Insulin Secretion in Carriers of Gene Variants in IRS-1 and -2
LM Hart, G Nijpels, JM Dekker, JA Maassen, RJ Heine, TW van Haeften |
Diabetes | 2002 |
|
RED BLOOD CELL Na + /H + EXCHANGE ACTIVITY IS INSULIN RESISTANT IN HYPERTENSIVE PATIENTS
JR Romero, A Rivera, PR Conlin |
Clinical and Experimental Hypertension | 2002 |
|
Apoptosis in the beta cells: cause or consequence of insulin secretion defect in diabetes?
G Sesti |
Annals of Medicine | 2002 |
|
Mouse models of insulin resistance
ML Hribal, F Oriente, D Accili |
American journal of physiology. Endocrinology and metabolism | 2002 |
|
GTK Tyrosine Kinase-induced Alteration of IRS-protein Signalling in Insulin Producing Cells
C Annerén, M Welsh |
Molecular Medicine | 2002 |
|
Review: Type 2 diabetes: how far have we come?
HE Lebovitz |
The British Journal of Diabetes & Vascular Disease | 2002 |
|
Understanding adipose tissue development from transgenic animal models
P Valet, G Tavernier, I Castan-Laurell, JS Saulnier-Blache, D Langin |
Journal of lipid research | 2002 |
|
Haploinsufficiency of peroxisome proliferator-activated receptor-gamma affects the B cell proliferative response and the severity of experimentally-induced arthritis
Keigo Setoguchi, Yoshikata Misaki, Yasuo Terauchi, Toshimasa Yamauchi, Kimito Kawahata, Takashi Kadowaki, Kazuhiko Yamamoto |
Journal of Clinical Investigation | 2001 |
|
Glucose homeostasis: lessons from knockout mice
J Nakae, Y Kido, T Kitamura, D Accili |
Current Opinion in Endocrinology & Diabetes | 2001 |
|
Environmental contaminants as etiologic factors for diabetes
MP Longnecker, JL Daniels |
Environmental Health Perspectives | 2001 |
|
Genetic determinants of type 2 diabetes mellitus
CP Busch, RA Hegele |
Clinical Genetics | 2001 |
|
Strategies for treating HIV-related lipodystrophy
MA García-Viejo, M Ruíz, E Martínez |
Expert Opinion on Investigational Drugs | 2001 |
|
PPAR.GAMMA. agonist and antagonist
T KADOWAKI |
Folia Pharmacologica Japonica | 2001 |
|
Tissue-specific insulin resistance in type 2 diabetes: lessons from gene-targeted mice
J Nakae, Y Kido, D Accili |
Annals of Medicine | 2001 |
|
Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes
T Imai, M Jiang, P Chambon, D Metzger |
Proceedings of the National Academy of Sciences | 2001 |
|
Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBbeta )
H Cho |
Science | 2001 |
|
Increased Expression of the Sterol Regulatory Element-binding Protein-1 Gene in Insulin Receptor Substrate-2 −/− Mouse Liver
K Tobe, R Suzuki, M Aoyama, T Yamauchi, J Kamon, N Kubota, Y Terauchi, J Matsui, Y Akanuma, S Kimura, J Tanaka, M Abe, J Ohsumi, R Nagai, T Kadowaki |
The Journal of biological chemistry | 2001 |
|
Mechanisms of Hepatic Very Low-Density Lipoprotein Overproduction in Insulin Resistance
K Adeli, C Taghibiglou, SC van Iderstine, GF Lewis |
Trends in Cardiovascular Medicine | 2001 |
|
Normal Akt/PKB with reduced PI3K activation in insulin-resistant mice
ST Nadler, JP Stoehr, ME Rabaglia, KL Schueler, MJ Birnbaum, AD Attie |
American journal of physiology. Endocrinology and metabolism | 2001 |
|
Insulin Control of Glycogen Metabolism in Knockout Mice Lacking the Muscle-Specific Protein Phosphatase PP1G/RGL
Y Suzuki, C Lanner, JH Kim, PG Vilardo, H Zhang, J Yang, LD Cooper, M Steele, A Kennedy, CB Bock, A Scrimgeour, JC Lawrence, AA DePaoli-Roach |
Molecular and cellular biology | 2001 |
|
Molekularmedizinische Grundlagen von Endokrinopathien
D Ganten, K Ruckpaul, OE Janssen, AE Heufelder |
2001 | |
|
Preserved Pancreatic β-Cell Development and Function in Mice Lacking the Insulin Receptor-Related Receptor
T Kitamura, Y Kido, S Nef, J Merenmies, LF Parada, D Accili |
Molecular and cellular biology | 2001 |
|
Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones
Lily Chao, Bernice Marcus-Samuels, Mark M. Mason, Jaideep Moitra, Charles Vinson, Elif Arioglu, Oksana Gavrilova, Marc L. Reitman |
Journal of Clinical Investigation | 2000 |
|
Unraveling the mechanism of action of thiazolidinediones
C. Ronald Kahn, Lihong Chen, Shmuel E. Cohen |
Journal of Clinical Investigation | 2000 |
|
Treatment of insulin resistance with peroxisome proliferator–activated receptor γ agonists
JM Olefsky |
Journal of Clinical Investigation | 2000 |
|
Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor alpha mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes
T Imai, M Jiang, P Chambon, D Metzger |
Proceedings of the National Academy of Sciences | 2000 |
Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)