Citations to this article

Sulfate Metabolism in Human Chondrocyte Cultures
Edith R. Schwartz, … , P. Roger Kirkpatrick, Roby C. Thompson
Edith R. Schwartz, … , P. Roger Kirkpatrick, Roby C. Thompson
Published November 1, 1974
Citation Information: J Clin Invest. 1974;54(5):1056-1063. https://doi.org/10.1172/JCI107849.
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Sulfate Metabolism in Human Chondrocyte Cultures

Abstract

The depletion of articular cartilage in the afflicted joints is a primary clinical feature of osteoarthritis. This disorder has been linked to a disturbance in the metabolism of the extracellular matrix components of this tissue. The mechanisms involved in the regulation of sulfated proteoglycan metabolism in articular cartilage were therefore studied by measuring the biosynthesis and distribution of 35S-labeled glycosaminoglycans in chondrocyte cultures derived from normal and osteoarthritic tissue. Incorporation experiments were carried out at pH 7.0 with [35S]Na2SO4 in the presence of fetal calf serum, human serum from normal or arthritic individuals, or a combination of these.

Authors

Edith R. Schwartz, P. Roger Kirkpatrick, Roby C. Thompson

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Total citations by year

Year: 2008 2001 1987 1986 1984 1983 1982 1981 1980 1979 1978 1977 1976 1975 Total
Citations: 1 1 1 2 1 1 2 2 3 4 1 2 2 1 24
Citation information

Citations to this article (24)

Title and authors Publication Year
Creating a spectrum of fibrocartilages through different cell sources and biochemical stimuli
GM Hoben, KA Athanasiou 		Biotechnology and Bioengineering 2008
In Vitro Generation of Scaffold Independent Neocartilage:
HD Adkisson, MP Gillis, EC Davis, W Maloney, KA Hruska 		Clinical Orthopaedics and Related Research® 2001
Mseleni disease serum is not harmful to cultured chondrocytes
Y Changlong, JE Fincham, GC Wright, JJ Taljaard, L Sokoloff 		Arthritis & Rheumatism 1987
Monensin stimulation of arylsulfatase B activity in human chondrocytes
JR Colofiore, ER Schwartz 		Journal of Orthopaedic Research 1986
In-Vitro Culture of Human Chondrocytes From Adult Subjectsm
A Delbruck, B Dresow, E Gurr, E Reale, H Schröder 		Connective Tissue Research 1986
Biosynthesis of Sulfated Proteoglycanin vitroby Cells Derived from Human Osteochondrophytic Spurs of the Femoral Head
CJ Malemud, RW Moskowitz, VM Goldberg 		Connective Tissue Research 1984
Comparative rates of proteoglycan synthesis and size of proteoglycans in normal and osteoarthritic chondrocytes
R Teshima, BV Treadwell, CA Trahan, HJ Mankin 		Arthritis & Rheumatism 1983
Characteristics of human chondrocyte cultures in completely defined medium
ER Schwartz, G Sugumaran 		In Vitro 1982
Proteoglycan synthesis in chondrocyte cultures from osteoarthrotic and normal human articular cartilage
MF Harmand, R Duphil, P Blanquet 		Biochimica et Biophysica Acta (BBA) - General Subjects 1982
Physiology of Articular Cartilage
CJ Malemud, RW Moskowitz 		Clinics in rheumatic diseases 1981
Characterization of a hyaluronic acid-dermatan sulfate proteoglycan complex from dedifferentiated human chondrocyte cultures
TR Oegema, RC Thompson 		The Journal of biological chemistry 1981
The Effect of Serum on Monolayer Cell Culture of Mammalian Articular Chondrocytes
YC Choi, GM Morris, FS Lee, L Sokoloff 		Connective Tissue Research 1980
Glycosaminoglycan metabolism of cultured cornea cells derived from bovine and human stroma and from bovine epithelium
H Bleckmann, H Kresse 		Experimental Eye Research 1980
The Joints and Synovial Fluid
DA McCARTY 		The Joints and Synovial Fluid 1980
Beeinflussung der Glykosaminoglykansynthese von kultivierten Stromazellen aus Rindercorneae durch Variation der Kulturbedingungen
H Bleckmann, H Kresse 		Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie 1979
Articular cartilage, blood serum glycosaminoglycans and glycoproteins in osteoarthritis deformans
NA Yusipova, AS Kriuk 		Clinica Chimica Acta 1979
Skeletal Research: an Experimental Approach
EA Tonna 		Skeletal Research: an Experimental Approach 1979
[Influence of glycosaminoglycan synthesis of cultured cornea stroma cells by variation of culture condition]
H Bleckmann, H Kresse 		Albrecht von Graefes Archiv f�r Klinische und Experimentelle Ophthalmologie 1979
Explant Culture of Human and Rabbit Articular Chondrocytes
CJ Malemud, DP Norby, L Sokoloff 		Connective Tissue Research 1978
Effect of ascorbic acid on arylsulfatase activities and sulfated proteoglycan metabolism in chondrocyte cultures
ER Schwartz, L Adamy 		Journal of Clinical Investigation 1977
Species differences in cell culture of mammalian articular chondrocytes
RJ Webber, CJ Malemud, L Sokoloff 		Calcified Tissue Research 1977
Inorganic pyrophosphate and proteoglycan metabolism in cultured human articular chondrocytes and fibroblasts
G Lust, G Nuki, JE Seegmiller 		Arthritis & Rheumatism 1976
Effect of Ascorbic Acid on Arylsulfatase A and B Activities in Human Chondrocyte Cultures
ER Schwartz, L Adamy 		Connective Tissue Research 1976
Chromatographically different type II collagens from human normal and osteoarthritic cartilage
M Fukae, GL Mechanic, L Adamy, ER Schwartz 		Biochemical and Biophysical Research Communications 1975

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