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Citations to this article

Familial Hypercholesterolemia (One Form of Familial Type II Hyperlipoproteinemia) A STUDY OF ITS BIOCHEMICAL, GENETIC, AND CLINICAL PRESENTATION IN CHILDHOOD
Peter O. Kwiterovich Jr., … , Donald S. Fredrickson, Robert I. Levy
Peter O. Kwiterovich Jr., … , Donald S. Fredrickson, Robert I. Levy
Published May 1, 1974
Citation Information: J Clin Invest. 1974;53(5):1237-1249. https://doi.org/10.1172/JCI107670.
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Familial Hypercholesterolemia (One Form of Familial Type II Hyperlipoproteinemia) A STUDY OF ITS BIOCHEMICAL, GENETIC, AND CLINICAL PRESENTATION IN CHILDHOOD

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Abstract

Primary hyperbetalipoproteinemia (type II hyperlipoproteinemia) is a common disorder associated with premature vascular disease. It is frequently due to genetic abnormalities, some of which are expressed in childhood. We have examined the manner in which that form of hyperbetalipoproteinemia known as familial hypercholesterolemia may be expressed in 236 children aged 1-19 born of 90 matings in which one parent had hyperbetalipoproteinemia of this variety and one parent did not.

Authors

Peter O. Kwiterovich Jr., Donald S. Fredrickson, Robert I. Levy

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CORONARY DISEASE-A CHILDHOOD MALADY
SC Mitchell
Cardiovascular diseases 1975
Hyperlipidaemia in children
JK Lloyd
British heart journal 1975
Familial hyper-alpha-lipoproteinemia: Studies in eighteen kindreds
CJ Glueck, RW Fallat, F Millett, P Gartside, RC Elston, RC Go
Metabolism 1975
Prospects for genetic screening
B Childs
The Journal of Pediatrics 1975
Serum lipid and lipoprotein profile in school children from a rural community
SR Srinivasan, RR Frerichs, GS Berenson
Clinica Chimica Acta 1975
Einundachtzigster Kongress
B Schlegel
1975
Lipids, Lipoproteins, and Drugs
D Kritchevsky, R Paoletti, WL Holmes
1975
Abnormal induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase in leukocytes from subjects with heterozygous familial hypercholesterolemia
AM Fogelman, J Edmond, J Seager, G Popják
The Journal of biological chemistry 1975

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