Citations to this article

A Specific Role for Saline or the Sodium Ion in the Regulation of Renin and Aldosterone Secretion
Michael L. Tuck, … , Robert G. Dluhy, Gordon H. Williams
Michael L. Tuck, … , Robert G. Dluhy, Gordon H. Williams
Published April 1, 1974
Citation Information: J Clin Invest. 1974;53(4):988-995. https://doi.org/10.1172/JCI107665.
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Research Article

A Specific Role for Saline or the Sodium Ion in the Regulation of Renin and Aldosterone Secretion

Abstract

It is well established that in normal man the renin-angiotensin-aldosterone system is responsive to changes in volume. The present study was performed to determine whether sodium has an action apart from volume in the regulation of the secretion of renin and aldosterone. Acute volume expansion was induced either by saline, dextran, or glucose infusion in supine, normal subjects in balance on a 10 meq sodium/100 meq potassium diet. Plasma renin activity (PRA), angiotensin II (A II), aldosterone (PA), cortisol, serum sodium, and potassium were measured every 10 min for the first 30 min and then at 1, 2, 4, 6, and 8 h.

Authors

Michael L. Tuck, Robert G. Dluhy, Gordon H. Williams

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Year: 2008 2005 1997 1993 1991 1988 1987 1986 1985 1982 1981 1979 1978 1977 1976 1975 Total
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Citations to this article (33)

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S Y Kim, H K Lee, C S Koh, H K Min 		The Korean Journal of Internal Medicine 1988
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C Prys-Roberts, MD Vickers 		1982
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I Eide, E Loyning, O Langård, F Kiil 		Circulation research 1977
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Selective hypoaldosteronism
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