Hyperglucagonemia of Renal Failure

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Abstract

Elevation of plasma glucagon concentration has been observed in starvation and illnesses associated with increased catabolism such as diabetes mellitus and severe infections. Thus, we examined plasma glucose, immunoreactive insulin (IRI, microunits per milliliter) and glucagon (IRG, picograms per milliliter) responses to a beef meal (1 g/kg body wt) and intravenous glucose (1.5 g/min for 45 min) in patients with chronic renal failure (CRF).

Authors

Gordon L. Bilbrey, Gerald R. Faloona, Martin G. White, James P. Knochel, Julio Borroto