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Citations to this article

Hypophyso-Gonadal Function in Humans during the First Year of Life: I. EVIDENCE FOR TESTICULAR ACTIVITY IN EARLY INFANCY
Maguelone G. Forest, … , Anne M. Cathiard, Jean Bertrand
Maguelone G. Forest, … , Anne M. Cathiard, Jean Bertrand
Published March 1, 1974
Citation Information: J Clin Invest. 1974;53(3):819-828. https://doi.org/10.1172/JCI107621.
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Hypophyso-Gonadal Function in Humans during the First Year of Life: I. EVIDENCE FOR TESTICULAR ACTIVITY IN EARLY INFANCY

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Abstract

Total and unbound testosterone and Δ4-androstenedione have been determined in 104 cord blood samples. The same sexual steroids and pituitary gonadotropins have been measured in 46 normal male infants aged 27-348 days and 34 normal female infants aged 19-332 days.

Authors

Maguelone G. Forest, Pierre C. Sizonenko, Anne M. Cathiard, Jean Bertrand

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R Rey
Journal of Pediatric Endocrinology and Metabolism 2003
Association of birth weight and breast-feeding with coronary heart disease risk factors at the age of 6 years
I Thorsdottir, I Gunnarsdottir, GI Palsson
Nutrition, Metabolism and Cardiovascular Diseases 2003
Leaching of Bisphenol A from New and Old Babies' Bottles, and New Babies' Feeding Teats
BL Tan, AM Mustafa
Asia-Pacific Journal of Public Health 2003
Relationship between growth and feeding in infancy and body mass index at the age of 6 years
I Gunnarsdottir, I Thorsdottir
International Journal of Obesity 2003
Serum Androgen Bioactivity in Cryptorchid and Noncryptorchid Boys during the Postnatal Reproductive Hormone Surge
T Raivio, J Toppari, M Kaleva, H Virtanen, AM Haavisto, L Dunkel, OA Jänne
The Journal of clinical endocrinology and metabolism 2003
Reproductive Hormones in Infant Girls—a Harbinger of Adult Reproductive Function?
MM Lee
The Journal of clinical endocrinology and metabolism 2003
Androgens in Health and Disease
CJ Bagatell, WJ Bremner
2003
Inhibins in childhood and puberty
T Raivio, L Dunkel
Best Practice & Research Clinical Endocrinology & Metabolism 2002
Androgen Imprinting of the Brain in Animal Models and Humans With Intersex Disorders: Review and Recommendations
Z Hrabovszky, JM Hutson
The Journal of Urology 2002
Cryptorchidism, Its Impact on Male Fertility
F Hadziselimovic
European Urology 2002
Size at Birth and Early Childhood Growth in Relation to Maternal Smoking, Parity and Infant Breast-Feeding: Longitudinal Birth Cohort Study and Analysis
KK Ong, MA Preece, PM Emmett, ML Ahmed, DB Dunger
Pediatric Research 2002
conduite à tenir devant la découverte d'un état intersexué lors d'une grossesse
Y Morel, V Tardy, L Calemard-Michel, L Guibaud, M Till, MG Forest
Journal de Pédiatrie et de Puériculture 2002
Pediatric Gender Assignment
SA Zderic, DA Canning, MC Carr, HM Snyder
2002
An ultrasensitive assay revealed age-related changes in serum oestradiol at low concentrations in both sexes from infancy to puberty
S Ikegami, T Moriwake, H Tanaka, M Inoue, T Kubo, S Suzuki, S Kanzaki, Y Seino
Clinical Endocrinology 2001
Developmental stage sensitivity and mode of action information for androgen agonists and antagonists
SY Euling, CA Kimmel
Science of The Total Environment 2001
Infancy is not a quiescent period of testicular development
HE Chemes
International Journal of Andrology 2001
Kinderurologie
A Sigel, RH Ringert
2001
The diagnostic and prognostic utility of prostate-specific antigen for diseases of the breast
MH Black, EP Diamandis
Breast Cancer Research and Treatment 2000
Pituitary-gonadal axis in male undermasculinisation
KL Ng, SF Ahmed, IA Hughes
Archives of disease in childhood 2000
Critical windows of exposure for children's health: the reproductive system in animals and humans
JL Pryor, C Hughes, W Foster, BF Hales, B Robaire
Environmental Health Perspectives 2000
Analysis of the Human Neonatal Thymus: Evidence for a Transient Thymic Involution
A Varas, E Jiménez, R Sacedón, M Rodríguez-Mahou, E Maroto, AG Zapata, A Vicente
Journal of immunology (Baltimore, Md. : 1950) 2000
Sexual dimorphism in the neonatal gonad
IA Hughes, N Coleman, SF Ahmed, KL Ng, A Cheng, HN Lim, JR Hawkins
Acta Paediatrica 1999
Manipulation of postnatal testosterone levels affects phallic and clitoral development in infant rhesus monkeys
Brown, Nevison, Fraser, Dixson
International Journal of Andrology 1999
Investigation of the Role of Postnatal Testosterone in the Expression of Sex Differences in Behavior in Infant Rhesus Macaques (Macaca mulatta)
GR Brown, AF Dixson
Hormones and Behavior 1999
Bloodspot Testosterone Assay Suitable for Study of Neonates and Monitoring of Children with Congenital Adrenal Hyperplasia
J Walker, IA Hughes, PJ Wood
Annals of Clinical Biochemistry 1999
Minipuberty of infancy and adolescent pubertal function in adrenal hypoplasia congenita
KB Kaiserman, JM Nakamoto, ME Geffner, ER McCabe
The Journal of Pediatrics 1998
The masculinized female and investigation of abnormal sexual development
IA Hughes
Baillière's Clinical Endocrinology and Metabolism 1998
Hormonal and cellular regulation of Sertoli cell anti-Müllerian hormone production in the postnatal mouse
L Al-Attar, K Noël, M Dutertre, C Belville, MG Forest, PS Burgoyne, N Josso, R Rey
Journal of Clinical Investigation 1997
Measurements of Serum Müllerian Inhibiting Substance in the Evaluation of Children with Nonpalpable Gonads
MM Lee, PK Donahoe, BL Silverman, T Hasegawa, Y Hasegawa, ML Gustafson, YC Chang, DT MacLaughlin
New England Journal of Medicine 1997
Active hypothalamic-pituitary-gonadal axis in an infant with X-linked adrenal hypoplasia congenita
T Takahashi, Y Shoji, Y Shoji, N Haraguchi, I Takahashi, G Takada
The Journal of Pediatrics 1997
Biosocial Bases of Violence
A Raine, PA Brennan, DP Farrington, SA Mednick
1997
Gynecological Endocrinology and Reproductive Medicine
B Runnebaum, T Rabe
1997
Abnormal gonadal differentiation in two subjects with ambiguous genitalia, Mullerian structures, and normally developed testes: Evidence for a defect in gonadal ridge development
JS Fuqua, ES Sher, EJ Perlman, MD Urban, M Ghahremani, J Pelletier, CJ Migeon, TR Brown, GD Berkovitz
Human Genetics 1996
Sex hormone-binding globulin and male sexual development
DA Damassa, JM Cates
Neuroscience & Biobehavioral Reviews 1995
Low-dose progestogen contraception and the nursing mother
VS Toddywalla, SB Patel, SS Betrabet
Advances in Contraception 1995
The Determination of Bio-Available Testosterone
MJ Wheeler
Annals of Clinical Biochemistry 1995
True hermaphroditism: Genetic variants and clinical management
CG Hadjiathanasiou, R Brauner, S Lortat-Jacob, S Nivot, M Jaubert, M Fellous, C Nihoul-Fekété, R Rappaport
The Journal of Pediatrics 1994
Gynäkologische Endokrinologie und Fortpflanzungsmedizin
B Runnebaum, T Rabe
1994
Steroid 17β-hydroxysteroid dehydrogenase deficiency in man: An inherited form of male pseudohermaphroditism
A Rösler
The Journal of Steroid Biochemistry and Molecular Biology 1992
2 The prenatal and postnatal development of the testis
J Müller, NE Skakkeb˦k
Baillière's Clinical Endocrinology and Metabolism 1992
Modes of Action of GnRH and GnRH Analogs
WF Crowley, PM Conn
1992
Ambigüedad sexual
JA Salcedo, G Malo
1992
Ovarian germ cell malignancies in England: epidemiological parallels with testicular cancer
IS Silva, AJ Swerdlow
British Journal of Cancer 1991
International Review of Cytology
RA Miller
International Review of Cytology 1991
Hormones and the Fetus
JR Pasqualini, FA Kincl✠, C Sumida
Hormones and the Fetus 1991
Early Postnatal Testicular Maldevelopment in Cryptorchidism
DS Huff, F Hadžiselimovič, HM Snyder, B Blyth, JW Duckett
The Journal of Urology 1991
Effect of 5-Alpha-Reductase Inhibitor, 4-MAPC, on Testicular Descent in Male Rat
MM Ngyuen, CA Lemmi, J Rajfer
The Journal of Urology 1991
Heterotypical Behaviour in Man and Animals
M Haug, PF Brain, C Aron
1991
Prenatal treatment of congenital adrenal hyperplasia: Report of a new case
GA Loeuille, M David, MG Forest
European Journal of Pediatrics 1990
Syndrome of mental retardation, facial anomalies, hypopituitarism, and distal arthrogryposis in sibs
D Chitayat, JG Hall, RM Couch, MS Phang, VJ Baldwin
American Journal of Medical Genetics 1990
A nomogram of the neonatal peak of urinary follicle stimulating hormone, luteinizing hormone and testosterone in normal male infants
SB Patel, SS Betrabet, ZK Shikary, VS Toddywalla
Indian Journal of Clinical Biochemistry 1990
CIRCULATING SEX HORMONE-BINDING GLOBULIN AND TESTOSTERONE IN NEWBORNS AND INFANTS
NJ Bolton, J Tapanainen, M Koivisto, R Vihko
Clinical Endocrinology 1989
Testis cancer: Post-natal hormonal factors, sexual behaviour and fertility
AJ Swerdlow, SR Huttly, PG Smith
International Journal of Cancer 1989
A Window for the Study of Prenatal Sex Hormone Influences on Postnatal Development
JA Finegan, B Bartleman, PY Wong
The Journal of Genetic Psychology 1989
Effects of Human Chorionic Gonadotropin, Androgens, Adrenocorticotropin Hormone, Dexamethasone and Hyperprolactinemia on Plasma Sex Steroid-Binding Protein
MG Forest, A Lecoq, M David, M Pugeat
Annals of the New York Academy of Sciences 1988
Pubertal neuroendocrine maturation: Early differentiation and stages of development
PA Lee
Adolescent and Pediatric Gynecology 1988
Androgen Receptor Levels and 5α-Reductase Activities in Preputial Skin and Chordee Tissue of Boys with Isolated Hypospadias
JP Gearhart, HR Linhard, GD Berkovitz, RD Jeffs, TR Brown
The Journal of Urology 1988
Abdominal Wall Defects and Cryoptorchidism: An Animal Model
DM Quinlan, JP Gearhart, RD Jeffs
The Journal of Urology 1988
Gonadal function in patients with Down syndrome
YH Hsiang, GD Berkovitz, GL Bland, CJ Migeon, AC Warren, JM Opitz, JF Reynolds
American Journal of Medical Genetics 1987
Hormones
AW Norman, G Litwack
Hormone Research 1987
Hormone Resistance and Other Endocrine Paradoxes
MP Cohen, PP Foà
1987
Gynäkologische Endokrinologie
B Runnebaum, T Rabe
Gynäkologische Endokrinologie 1987
Pubertal endocrinology of yellow baboon (Papio cynocephalus): Plasma testosterone, testis size, body weight, and crown-rump length in males
VD Castracane, KC Copeland, P Reyes, TJ Kuehl
American Journal of Primatology 1986
Androgen resistance in the neonate: Use of hormones of hypothalamic-pituitary-gonadal axis for diagnosis
RA Nagel, BM Lippe, JE Griffin
The Journal of Pediatrics 1986
H-Y intermediate phenotype in male pseudohermaphroditism
TA Wilson, SS Wachtel, S Howards, J Lininger, A Johanson
The Journal of Pediatrics 1986
Indian Council of Medical Research ICMR Task Force Study on hormonal contraceptives
ZK Shikary, SS Betrabet, VS Toddywala, DM Patel, S Datey, BN Saxena
Contraception 1986
The Prevalence of 5 α -Reductase Deficiency in Children with Ambiguous Genitalia in the Dominican Republic
J Imperato-McGinley, T Gautier, RE Peterson, C Shackleton
The Journal of Urology 1986
The Significance of Postnatal Gonadotropin Surge for Testicular Development in Normal and Cryptorchid Testes
F Hadžiselimovič, L Thommen, J Girard, B Herzog
The Journal of Urology 1986
Human Growth
F Falkner, JM Tanner
1986
Steroid Hormone Resistance
GP Chrousos, DL Loriaux, MB Lipsett
1986
The relation of relative hormonal levels and physical development and social-emotional behavior in young adolescents
EJ Susman, ED Nottelmann, GE Inoff-Germain, LD Dorn, GB Cutler, DL Loriaux, GP Chrousos
Journal of Youth and Adolescence 1985
Sexual maturation of the hypothalamus: Pathophysiological aspects and clinical implications
MG Forest
Acta Neurochirurgica 1985
Individual differences in mood in early childhood: Their relation to gender and neonatal sex steroids
J Marcus, EE Maccoby, CN Jacklin, CH Doering
Developmental Psychobiology 1985
Pituitary and gonadal function in the infant son of a patient with hypogonadofropic hypogonadism
FG Cassorla, O Pescovitz, DL Loriaux, RJ Sherins
Journal of Endocrinological Investigation 1985
The Development of Expressive Behavior
CZ Malatesta
The Development of Expressive Behavior 1985
Contemporary Endocrinology
SH Ingbar
1985
Actions of Progesterone on the Brain
D Ganten, D Pfaff
1985
Maturation of the Human Testicular Response to hCG
MG Forest
Annals of the New York Academy of Sciences 1984
Sexual behavior of male rats: Influence of short- and long-term adrenalectomy
R Poggioli, AV Vergoni, R Santi, C Carani, GF Baraghini, D Zini, P Marrama, A Bertolini
Hormones and Behavior 1984
Neonatal sex-steroid hormones and muscular strength of boys and girls in the first three years
CN Jacklin, EE Maccoby, CH Doering, DR King
Developmental Psychobiology 1984
Abnormal sex differentiation
P Saenger
The Journal of Pediatrics 1984
Male-Limited Familial Precocious Puberty in Three Generations: Apparent Leydig-Cell Autonomy and Elevated Glycoprotein Hormone Alpha Subunit
EO Reiter, RS Brown, C Longcope, IZ Beitins
New England Journal of Medicine 1984
Follicular fluid inhibin activity and steroid levels in ovarian tissue obtained at autopsy from human infants from 18 to 200 days of age**Supported in part by National Institute of Child Health and Human Development grant HD08834
CP Channing, M Chacon, K Tanabe, P Gagliano, T Tildon
Fertility and Sterility 1984
Stimulatory effects of follicle-stimulating hormone and luteinizing hormone upon secretion of progesterone and inhibin activity by cultured infant human ovarian granulosa cells**Supported in part by grant HD-08834 from the National Institute of Child Health and Human Development
CP Channing, K Tanabe, M Chacon, JT Tildon
Fertility and Sterility 1984
Paediatric Endocrinology in Clinical Practice
A Aynsley-Green
1984
Dihydrotestosterone levels at midpregnancy and term: a comparison with testosterone concentrations
DR Abramovich, R Herriot, J Stott
BJOG: An International Journal of Obstetrics and Gynaecology 1983
Possible Testicular 3β-Hydroxysteroid Dehydrogenase Deficiency in Chryptorchid Neonates
F Facchinetti, R Bracci, S Sardelli, MG Vanni, F Bagnoli, AR Genazzani
Systems Biology in Reproductive Medicine 1983
The Neuroendocrine Aspects of Reproduction
RF Casper, SS Yen
The Neuroendocrine Aspects of Reproduction 1983
Maturation of the hypothalamic-pituitary-gonadal axis in the male lamb: A review
R Collu, S Savoie, R Hamel, W Gibb, JR Ducharme
Psychoneuroendocrinology 1983
Adrenal Function in Women with Idiopathic Acne
GP Chrousos, GL Peck, EG Gross, GB Cutler, DL Loriaux
Journal of Investigative Dermatology 1982
Testosterone concentration within the tunica vaginalis of boys and adult men
B Karpe, B Fredricsson, J Svensson, EM Ritzén
International Journal of Andrology 1982
Pubertal development: Normal, precocious and delayed
JR Ducharme, R Collu
Clinics in Endocrinology and Metabolism 1982
Developmental androgen fluctuations and the five dimensions of mammalian sex (with emphasis upon the behavioral dimension and the human species)
L Ellis
Ethology and Sociobiology 1982
Incidence of Cryptorchidism
HL Frey, J Rajfer
The Urologic clinics of North America 1982
Testicular volume during early infancy
FG Cassorla, SM Golden, RE Johnsonbaugh, WM Heroman, DL Loriaux, RJ Sherins
The Journal of Pediatrics 1981
Pulsatile secretion of gonadotropins in early infancy
F Waldhauser, G Weienbacher, H Frisch, A Pollak
European Journal of Pediatrics 1981
Hypopyso-gonadal and hypophyso-adrenal function in boys with discordance between pubic hair and genital development
E Cacciari, A Cicognani, P Pirazzoli, F Bernardi, F Zappulla, S Salardi, L Mazzanti, E Fréjaville, R Bergamaschi, M P Villa
European Journal of Pediatrics 1981
Testicular and adrenal androgens and their binding to plasma proteins in the perinatal period: Developmental patterns of plasma testosterone, 4-androstenedione, dehydroepiandrosterone and its sulfate in premature and small for date infants as compared with that of full-term infants
MG Forest, E Peretti, J Bertrand
Journal of Steroid Biochemistry 1980
Plasma gonadotropin and testosterone values in infants with cryptorchidism
D Gendrel, M Roger, JC Job
The Journal of Pediatrics 1980
Simultaneous postnatal rise of plasma LH and testosterone in male infants
D Gendrel, JL Chaussain, M Roger, JC Job
The Journal of Pediatrics 1980
Developmental patterns of plasma dehydroepiandrosterone sulfate and testosterone in male pigs
HS Tan, JI Raeside
Animal Reproduction Science 1980
Maternal Serum Human Chorionic Gonadotropin Concentrations and Fetal Sex Prediction
H Danzer, GD Braunstein, J Rasor, A Forsythe, ME Wade
Fertility and Sterility 1980
Success, relapse and failure after intranasal LHRH treatment of cryptorchidism in 55 prepubertal boys
R Illig, H Bucher, A Prader
European Journal of Pediatrics 1980
EARLY DETERMINATION OF ANDROGEN-RESPONSIVENESS IS IMPORTANT IN THE MANAGEMENT OF MICROPHALLUS
S Burstein, MM Grumbach, SL Kaplan
The Lancet 1979
Concentrations of Sex Hormones in Umbilical-Cord Blood: Their Relation to Sex and Birth Order of Infants
EE Maccoby, CH Doering, CN Jacklin, H Kraemer
Child Development 1979
Plasma androgens (Testosterone and 4-androstenedione) and 17-hydroxyprogesterone in the neonatal, prepubertal and peripubertal periods in the human and the rat: Differences between species
MG Forest
Journal of Steroid Biochemistry 1979
Sequential hormonal changes and activation of the hypothalamic-pituitary-gonadal axis
JR Ducharme, S Catin-Savoie, Y Taché, B Bourel, R Collu
Journal of Steroid Biochemistry 1979
Hormonal Steroids
W Nowaczynski, P Landais, T Murakami, M Nowaczynski, D Mavoungou, B Vitullo
Hormonal Steroids 1979
Case 23-1979: Sexual Precocity in a Six-Year-Old Girl
RC Cabot, RE Scully, JJ Galdabini, BU McNeely, B Kliman, GR Dickersin
New England Journal of Medicine 1979
Studies on the subunits of the human glycoprotein hormones in relation to reproduction
C Hagen
Scandinavian Journal of Clinical & Laboratory Investigation 1978
VARIATIONS OF SERUM TESTOSTERONE ESTRADIOL BINDING GLOBULIN (TeBG) BINDING CAPACITY IN INFANTS DURING THE FIRST YEAR OF LIFE
JL Chaussain, A Brijawi, P Georges, M Roger, M Donnadieu, JC Job
Acta Paediatrica 1978
True hermaphroditism: A clinical description and a proposed function for the long arm of the Y chromosome
PK Donahoe, JD Crawford, WH Hendren
Journal of Pediatric Surgery 1978
Maternal peripheral testosterone levels during the first half of pregnancy
K Klinga, E Bek, B Runnebaum
American Journal of Obstetrics and Gynecology 1978
The gonadotrophins and their subunits in foetal pituitary glands and circulation
C Hagen, AS McNeilly
Journal of Steroid Biochemistry 1977
Clinical Neuroendocrinology
CR Edwards
Clinical Neuroendocrinology 1977
Management of neonates and children with male pseudohermaphroditism
PK Donahoe, JD Crawford, WH Hendren
Journal of Pediatric Surgery 1977
MALE PSEUDOHERMAPHRODITISM WITH HYPERTENSION DUE TO A 17α-HYDROXYLATION DEFICIENCY
J Tourniaire, L Audi-Parera, B Loras, J Blum, P Castelnovo, MG Forest
Clinical Endocrinology 1976
HYPOTHALAMIC-PITUITARY-GONADAL RELATIONSHIPS IN MAN FROM BIRTH TO PUBERTY
MG Forest, E Peretti, J Bertrand
Clinical Endocrinology 1976
HCG stimulation test in children with abnormal sexual development
DB Grant, BM Laurance, SM Atherden, J Ryness
Archives of disease in childhood 1976
Proceedings of the 1975 Laurentian Hormone Conference
J Genest, W Nowaczynski, O Kuchel, R Boucher, J Rojo-Ortega, G Constantopoulos, D Ganten, F Messerli
Proceedings of the 1975 Laurentian Hormone Conference 1976
ACTH and prostaglandin receptors in human adrenocortical tumors. Apparent modification of a specific component of the ACTH-binding site
JM Saez, A Dazord, D Gallet
Journal of Clinical Investigation 1975
Effects of fetal decapitation on the structure and function of leydig cells in rhesus monkeys (Macaca mulatta)
MT Tseng, NJ Alexander, GW Kittinger
American Journal of Anatomy 1975
Differentiation and development of the male
MG Forest
Clinics in Endocrinology and Metabolism 1975
What lessons can be learned from testicular histology in undescended testes?
Clay W. Mechlin, Barry A. Kogan
Translational andrology and urology
Regulation of Gonadotropin Secretion in Man
RM Boyar
Medical Clinics of North America 1978
Principles and Prenatal Growth
F Falkner, JM Tanner
1978
Aktuelle Probleme der pädiatrischen Endokrinologie: Symposium, Wien, 28. September 1976
W Swoboda, H Zimprich
1977
Steroids after birth-puberty
WA Marshall
Postgraduate medical journal 1976
The Year in Endocrinology, 1975–1976
SH Ingbar
1976
Patterns of Gonadotrophins and Gonadal Steroids throughout Life
C Faiman, JS Winter, FI Reyes
1976
Hormonal Changes of Adolescence
EO Reiter, AW Root
Medical Clinics of North America 1975
Serum human chorionic gonadotropin and progesterone patterns in the last trimester of pregnancy: Relationship to fetal sex
RS Boroditsky, FI Reyes, JS Winter, C Faiman
American Journal of Obstetrics and Gynecology 1975
Micropenis associated with testicular agenesis.
Grant DB, Dillon MJ
Archives of disease in childhood 1975
Infertility
AL Case, FP Zuspan
Surgical Clinics of North America 1969
Postnatal weight and height growth velocities at different ages between birth and 5 y and body composition in adolescent boys and girls
Jérémie Botton, Barbara Heude, Jean Maccario, Pierre Ducimetière, Marie-Aline Charles,
The American journal of clinical nutrition
Establishing reference values for age-related spermatogonial quantity in prepubertal human testes: a systematic review and meta-analysis
I Masliukaite, JM Hagen, K Jahnukainen, JB Stukenborg, S Repping, F der Veen, M Wely, AM van Pelt
Fertility and Sterility 2016

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