Citations to this article

Circadian Rhythm of Plasma Aldosterone Concentration in Patients with Primary Aldosteronism
David C. Kem, … , Shunsuke Furuyama, Charles A. Nugent
David C. Kem, … , Shunsuke Furuyama, Charles A. Nugent
Published September 1, 1973
Citation Information: J Clin Invest. 1973;52(9):2272-2277. https://doi.org/10.1172/JCI107414.
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Research Article

Circadian Rhythm of Plasma Aldosterone Concentration in Patients with Primary Aldosteronism

Abstract

Plasma aldosterone, cortisol, and renin activity were measured in nine recumbent patients with hyperaldosteronism, including seven with adenomas, one with idiopathic hyperplasia, and one with glucocorticoid suppressible hyperplasia. All had peak values of plasma aldosterone concentration from 3 a.m. to noon and lowest values at 6 p.m. or midnight. This rhythm was similar to the circadian pattern of plasma cortisol in the same patients. When these data were normalized to eliminate the wide variation in ranges of plasma aldosterone and cortisol between individuals, there was an excellent correlation (r = + 0.87, P < 0.005) between the two hormones. In contrast, plasma aldosterone concentrations did not correlate with plasma renin activity before or after normalization of data.

Authors

David C. Kem, Myron H. Weinberger, Celso Gomez-Sanchez, Norman J. Kramer, Robert Lerman, Shunsuke Furuyama, Charles A. Nugent

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Citations to this article (70)

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Using LC-MS/MS to Determine Salivary Steroid Reference Intervals in a European Older Adult Population.
Gregory S, Denham SG, Lee P, Simpson JP, Homer NZM 		Metabolites 2023
Aldosterone: Essential for Life but Damaging to the Vascular Endothelium
Crompton M, Skinner LJ, Satchell SC, Butler MJ 		Biomolecules 2023
Influence of autonomous cortisol secretion in patients with primary aldosteronism: subtype analysis and postoperative outcome.
Hung K, Lee BC, Chen PT, Liu KL, Chang CC, Wu VC, Lin YH 		Endocrine Connections 2023
Current perspective on circadian function of the kidney
Benjamin JI, Pollock DM 		AJP Renal Physiology 2023
Aldosterone-Regulated Sodium Transport and Blood Pressure
Tsilosani A, Gao C, Zhang W 		Frontiers in physiology 2022
Circadian Rhythm Sleep-Wake Disorders: An Evidence-Based Guide for Clinicians and Investigators
RR Auger 		2020
Intravenous administration of ghrelin increases serum cortisol and aldosterone concentrations in heavy-drinking alcohol-dependent individuals: Results from a double-blind, placebo-controlled human laboratory study
CL Haass-Koffler, VM Long, M Farokhnia, M Magill, GA Kenna, RM Swift, L Leggio 		Neuropharmacology 2019
Efficient screening of patients with aldosterone-producing adenoma using the ACTH stimulation test
T Kita, E Furukoji, T Sakae, K Kitamura 		Hypertension Research 2019
Diurnal rhythm in clinical chemistry: An underrated source of variation
MA Hassan, E Delvin, MO Elnenaei, B Hoffman 		Critical Reviews in Clinical Laboratory Sciences 2018
Subtype prediction in primary aldosteronism: measurement of circadian variation of adrenocortical hormones and 24-h urinary aldosterone
H Kobayashi, A Haketa, T Ueno, R Suzuki, N Aoi, Y Ikeda, K Tahira, Y Hatanaka, S Tanaka, H Otsuka, M Abe, N Fukuda, M Soma 		Clinical Endocrinology 2016
Evaluation of right adrenal vein anatomy by Dyna computed tomography in patients with primary aldosteronism
BC Lee, CC Chang, KL Liu, YC Chang, VC Wu, KH Huang 		Scientific Reports 2016
Non-stimulated adrenal venous sampling using Dyna computed tomography in patients with primary aldosteronism
CC Chang, BC Lee, KL Liu, YC Chang, VC Wu, KH Huang 		Scientific Reports 2016
Role of endogenous ACTH on circadian aldosterone rhythm in patients with primary aldosteronism
Takuhiro Sonoyama, Masakatsu Sone, Naohisa Tamura, Kyoko Honda, Daisuke Taura, Katsutoshi Kojima, Yorihide Fukuda, Naotetsu Kanamoto, Masako Miura, Akihiro Yasoda, Hiroshi Arai, Hiroshi Itoh, Kazuwa Nakao 		2014
Role of endogenous ACTH on circadian aldosterone rhythm in patients with primary aldosteronism
Takuhiro Sonoyama, Masakatsu Sone, Naohisa Tamura, Kyoko Honda, Daisuke Taura, Katsutoshi Kojima, Yorihide Fukuda, Naotetsu Kanamoto, Masako Miura, Akihiro Yasoda, Hiroshi Arai, Hiroshi Itoh, Kazuwa Nakao 		2014
Reference Module in Biomedical Sciences
DL Sackett, RB Haynes 		2014
Twenty-four-hour urinary aldosterone predicts inappropriate left ventricular mass index in patients with primary aldosteronism
CS Hung, YL Ho, YY Chang, VC Wu, XM Wu, JK Lee, SC Chueh, YH Lin, YS Changh, SY Yang, YH Hu, MJ Sui, MF Chen, KD Wu 		The Scientific World JOURNAL 2013
Difficult-to-control hypertension due to bilateral aldosterone-producing adrenocortical microadenomas associated with a cortisol-producing adrenal macroadenoma
R Morimoto, M Kudo, O Murakami, K Takase, S Ishidoya, Y Nakamura, T Ishibashi, S Takahashi, Y Arai, T Suzuki, H Sasano, S Ito, F Satoh 		Journal of Human Hypertension 2010
Progress in Primary Aldosteronism: Present Challenges and Perspectives
CE Gomez-Sanchez, GP Rossi, F Fallo, M Mannelli 		Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2010
A possible association between aldosterone response to vasopressin and circadian change of aldosterone in the patients with aldosterone-producing adenoma
S Suzuki, D Uchida, H Koide, K Suyama, T Shibata, T Yoshida, T Tanaka, Y Noguchi, Y Saito, I Tatsuno 		Peptides 2008
Saliva as a medium for aldosterone measurement in repeated sampling studies
J Manolopoulou, P Mulatero, C Maser-Gluth, P Rossignol, A Spyroglou, Y Vakrilova, S Petersenn, O Zwermann, PF Plouin, M Reincke, M Bidlingmaier 		Steroids 2008
Plasma and urine aldosterone to plasma renin activity ratio in the diagnosis of primary aldosteronism
G Bernini, A Moretti, C Orlandini, P Berti, P Miccoli, M Bardini, C Taurino, M Bernini, A Salvetti 		Journal of Hypertension 2008
To stimulate or not to stimulate: is adrenocorticotrophic hormone testing necessary, or not?
M Tanemoto, F Satoh, T Abe, S Ito 		Journal of Hypertension 2007
Diurnal blood pressure pattern in patients with primary aldosteronism
S Zacharieva, M Orbetzova, A Elenkova, A Stoynev, M Yaneva, R Schigarminova, K Kalinov, E Nachev 		Journal of Endocrinological Investigation 2006
Comparison of adrenal vein sampling value between aldosterone producing adrenal adenoma and non-functioning adrenal adenoma: evaluation using receiver operating characteristic analysis
Y Baba, H Hokotate, M Nakajo 		Acta Radiologica 2005
Surgery
JA Norton, RR Bollinger, AE Chang, SF Lowry, SJ Mulvihill, HI Pass, RW Thompson 		Surgery 2001
Pathophysiology and diagnosis of primary aldosteronism
H Suzuki 		Biomedecine & Pharmacotherapy 2000
Endogenous dopaminergic activity in Child-Pugh A cirrhosis: potential role in renal sodium handling and in the maintenance of clinical compensation
Sansoe, Ferrari, Baraldi, Grisolia, De Santis, Villa, Manenti 		European Journal of Clinical Investigation 1998
Endocrinology of Cardiovascular Function
ER Levin, JL Nadler 		1998
Primary aldosteronism. Part II Differential diagnosis of primary hyperaldosteronism and pseudoaldosteronism
MB Vallotton 		Clinical Endocrinology 1996
Primary aldosteronism. Part I Diagnosis of primary hyperaldosteronism
MB Vallotton 		Clinical Endocrinology 1996
Nocturnal blood pressure in normotensive subjects and those with white coat, primary, and secondary hypertension
M Middeke, J Schrader 		BMJ (Clinical research ed.) 1994
Circadian blood pressure variation in patients with renovascular hypertension or primary aldosteronisn
Y Imai, K Abe, S Sasaki, M Munakata, N Minami, H Sakuma, J Hashimoto, T Yabe, N Watanabe, M Sakuma, K Tsunoda, H Sekino, K Imai, K Yoshinaga 		Clinical and Experimental Hypertension 1992
Cellular origin of aldosteronomas
A Ganguly 		The Clinical Investigator 1992
Circadian Blood Pressure Rhythm in Primary and Secondary Hypertension
M Middeke, M Klüglich, H Holzgreve 		Chronobiology International 1991
ALDOSTERONE REGULATION DURING SALINE INFUSION: USEFULNESS OF ALDOSTERONE/CORTISOL RATIO IN THE DIAGNOSIS OF ALDOSTERONE-PRODUCING ADENOMA
SM Hamlet, TJ Tunny, SA Klemm, RD Gordon 		Clinical and Experimental Pharmacology and Physiology 1987
Chronobiological study of factors affecting plasma aldosterone concentration in cirrhosis
M Bernardi, R Palma, F Trevisani, C Santini, F Capani, M Baraldini, G Gasbarrini 		Gastroenterology 1986
Use of the saline infusion test to diagnose the cause of primary aldosteronism
E Arteaga, R Klein, EG Biglieri 		The American Journal of Medicine 1985
Adrenal Cortex
LE Gustavson, LZ Benet 		Adrenal Cortex 1985
May a lymphocytic infiltration have a pathogenic role in an aldosterone-producing adrenal tumor?
P Cugini, P Lucia, C Letizia, G Murano, S Pièche 		Medical Hypotheses 1985
Hormone and Blood Pressure Relationships in Primary Aldosteronism
MG Nicholls, EA Espiner, H Ikram, AH Maslowski, EJ Hamilton, PJ Bones 		Clinical and Experimental Hypertension 1984
Idiopathic Hyperaldosteronism: A Possible Role for Aldosterone-Stimulating Factor
RM Carey, S Sen, LM Dolan, CD Malchoff, FM Bumpus 		New England Journal of Medicine 1984
Primary hyperaldosteronism in childhood due to unilateral macronodular hyperplasia. Case report
SE Oberfield, LS Levine, A Firpo, D Lawrence, E Stoner, DJ Levy, S Sen, MI New 		Hypertension 1984
Primary Aldosteronism: Pathophysiology, Diagnosis and Treatment
A Ganguly, JP Donohue 		The Journal of Urology 1983
Mineralocorticoids and Hypertension
W Kaufmann, G Wambach, A Helber, KA Meurer 		1983
Clinical and biochemical features of patients with aldosterone-producing adenoma and idiopathic hyperaldosteronism
H Witzgall, OA Mller, PC Weber 		Klinische Wochenschrift 1983
Primary Aldosteronism: Effects of Inhibition of ACTH and Potassium Administration on Plasma Aldosterone Concentration
A Ganguly, JA Luetscher, MH Weinberger, JA Haley 		Clinical and Experimental Hypertension 1982
Restoration of Renin-Aldosterone Dynamics to Normal Following Surgery in Primary Aldosteronism
MH Weinberger, CE Grim, NJ Kramer, A Ganguly 		Clinical and Experimental Hypertension 1982
Stimulation of aldosterone secretion by metoclopramide in humans: Apparent independence of renal and pituitary mediation
JH Pratt, A Ganguly, CA Parkinson, MH Weinberger 		Metabolism 1981
2 Primary hyperaldosteronism
JB Ferriss, JJ Brown, R Fraser, AF Lever, JI Robertson 		Clinics in Endocrinology and Metabolism 1981
Anomalous Postural Aldosterone Response in Glucocorticoid-Suppressible Hyperaldosteronism
A Ganguly, CE Grim, MH Weinberger 		New England Journal of Medicine 1981
Primary hyperaldosteronism
BA Scoggins, JP Coghlan 		Pharmacology & Therapeutics 1980
ALDOSTERONE REGULATION IN PRIMARY ALDOSTERONISM: INFLUENCE OF SALT BALANCE, POSTURE AND ACTH
EA Espiner, RA Donald 		Clinical Endocrinology 1980
Activity of [des-Aspartyl1]-Angiotensin II in Primary Aldosteronism
RM Carey, CR Ayers, ED Vaughan, MJ Peach, SM Herf 		Journal of Clinical Investigation 1979
Renin, aldosterone and Cortisol during ethanol intoxication and hangover
J Linkola, F Fyhrquist, R Ylikahri 		Acta Physiologica Scandinavica 1979
Aldosterone Producing Adenoma: Fludrocortisone Suppression and Left Adrenal Vein Catheterisation in Definitive Diagnosis and Management
RD Gordon, RV Jackson, CR Strakosch, TJ Tunny, JC Rutherford, J McCosker, W Moriarty 		Australian and New Zealand Journal of Medicine 1979
Identification and differentiation of surgically correctable hypertension due to primary aldosteronism
SM Herf, DC Teates, CJ Tegtmeyer, ED Vaughan, CR Ayers, RM Carey 		The American Journal of Medicine 1979
Responses of plasma renin activity and dopamine-beta-hydroxylase to increased intravascular volume
F Lamprecht, WL Miller, T Kawasaki, FC Bartter 		Journal of Neural Transmission 1979
Low-renin (“primary”) hyperaldosteronism
JB Ferriss, DG Beevers, JJ Brown, R Fraser, AF Lever, PL Padfield, JI Robertson 		American Heart Journal 1978
Concurrent hypercortisolism and hypermineralocorticoidism
MJ Hogan, M Schambelan, EG Biglieri 		The American Journal of Medicine 1977
The diagnosis and management of disorders of aldosterone production
P Mulrow, R Noth, A Fernandez-Cruz 		Pharmacology & Therapeutics Part C Clinical Pharmacology and Therapeutics 1976
The adrenal cortex and hypertension: Some observations on a possible role for mineralocorticoids other than aldosterone
R Fraser, JJ Brown, WC Brown, JB Ferriss, A Kennedy, AF Lever, PA Mason, JJ Morton, MG Nicholls, LE Ramsay, JI Robertson, MA Schalekamp, A Wilson 		Journal of Steroid Biochemistry 1976
Location of Aldosterone-Producing Adenomas with 131 I-19-Iodocholesterol
MJ Hogan, J McRae, M Schambelan, EG Biglieri 		New England Journal of Medicine 1976
Tagesprofile von Plasmaaldosteron,-Cortisol, -Renin, -Angiotensinogen und -Angiotensinasen bei Normalpersonen
D Lommer, A Distler, HP Nast, K Sinterhauf, U Walter, HP Wolff, K Sieler 		Klinische Wochenschrift 1976
The Year in Endocrinology, 1975–1976
SH Ingbar 		1976
Proceedings of the 1974 Laurentian Hormone Conference
H Valtin, HW Sokol, D Sunde 		Proceedings of the 1974 Laurentian Hormone Conference 1975
Control of plasma aldosterone in a patient with Conn's Syndrome before and during spironolactone medication
H Vetter, W Vetter 		Klinische Wochenschrift 1975
Anatomical and Physio-Pathological Basis of Neurohypophysial - Renal - Adrenal Feed-Back Systems Controlling Renal Function
WJ Dempster 		1974
Aldosteronism
JA Luetscher 		Disease-a-Month 1964
Primary Aldosteronism
AJ Hellem 		Acta Medica Scandinavica 1956

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