Citations to this article

Effects of Cycloheximide on the Response of Intestinal Mucosa to Cholera Enterotoxin
Daniel V. Kimberg, … , Robert T. Schooley, Antonia Henderson
Daniel V. Kimberg, … , Robert T. Schooley, Antonia Henderson
Published June 1, 1973
Citation Information: J Clin Invest. 1973;52(6):1376-1383. https://doi.org/10.1172/JCI107310.
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Research Article

Effects of Cycloheximide on the Response of Intestinal Mucosa to Cholera Enterotoxin

Abstract

Prior studies have indicated that effects of cholera enterotoxin (CT) on the small intestine are delayed in onset and involve an interaction with adenyl cyclase in the mucosa. It has also been shown that the administration of cycloheximide to rabbits in doses which inhibit crypt cell mitoses (20 mg/kg), diminishes CT-induced fluid production in jejunal loops. These latter studies have been interpreted as indications that CT-related intestinal secretion is a crypt cell function and that it is mediated by a CT-induced protein.

Authors

Daniel V. Kimberg, Michael Field, Elaine Gershon, Robert T. Schooley, Antonia Henderson

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Year: 2013 2001 1999 1997 1996 1989 1987 1982 1980 1979 1978 1977 1976 1975 1974 1973 Total
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Citations to this article (41)

Title and authors Publication Year
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Changes in cyclic 3'5‘-adenosine monophosphate tissue concentration and net fluid transport in the cat's small intestine elicited by cholera toxin, arachidonic acid, vasoactive intestinal polypeptide and 5-hydroxytryptamine
S Eklund, I Brunsson, M Jodal, O Lundgren 		Acta Physiologica Scandinavica 1987
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S Miura, H Asakura, T Morishita, T Hibi, Y Munakata, K Kobayashi, M Tsuchiya 		Gut 1982
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AM Feldman, MH Epstein, SW Brusilow 		Brain Research 1979
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L Turnberg 		1979
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TE Andreoli, JF Hoffman, DD Fanestil 		1978
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The Specificity and Action of Animal, Bacterial and Plant Toxins
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U Hopfer 		Proceedings of the National Academy of Sciences 1975
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MW Bitensky, MA Wheeler, H Mehta, N Miki 		Proceedings of the National Academy of Sciences 1975
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Adenylate Cyclase in Intestinal Crypt and Villus Cells: Stimulation by Cholera Enterotoxin and Prostaglandin E1
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V Bennett, L Mong, P Cuatrecasas 		The Journal of Membrane Biology 1975
Effects of Prostaglandins and Cholera Enterotoxin on Intestinal Mucosal Cyclic AMP Accumulation EVIDENCE AGAINST AN ESSENTIAL ROLE FOR PROSTAGLANDINS IN THE ACTION OF TOXIN
DV Kimberg, M Field, E Gershon, A Henderson 		Journal of Clinical Investigation 1974
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Intestinal Secretion
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Alkaline Phosphatase. POSSIBLE INDUCTION BY CYCLIC AMP AFTER CHOLERA ENTEROTOXIN ADMINISTRATION
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