Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Citations to this article

Mechanisms of Immune Lysis of Red Blood Cells In Vitro I. PAROXYSMAL NOCTURNAL HEMOGLOBINURIA CELLS
Gerald L. Logue, … , Wendell F. Rosse, Judith P. Adams
Gerald L. Logue, … , Wendell F. Rosse, Judith P. Adams
Published May 1, 1973
Citation Information: J Clin Invest. 1973;52(5):1129-1137. https://doi.org/10.1172/JCI107279.
View: Text | PDF
Research Article

Mechanisms of Immune Lysis of Red Blood Cells In Vitro I. PAROXYSMAL NOCTURNAL HEMOGLOBINURIA CELLS

  • Text
  • PDF
Abstract

The effect of five different reactions which activate complement (antibody activation, reduction in ionic strength, acidification, cobra venom factor (CoF) activation, and inulin activation) upon normal and PNH cells was investigated, using normal serum and serum devoid of the fourth component of complement (C4) activity from patients with hereditary angioneurotic edema (HANE) as a source of complement.

Authors

Gerald L. Logue, Wendell F. Rosse, Judith P. Adams

×

Total citations by year

Year: 2020 2017 2016 2012 2010 2008 2006 2000 1998 1997 1992 1991 1990 1989 1988 1987 1986 1985 1984 1983 1982 1981 1980 1979 1978 1977 1975 1974 1973 1969 Total
Citations: 2 2 1 1 2 3 1 1 1 2 1 1 3 1 1 2 1 2 2 4 2 1 1 4 2 4 2 6 2 1 59
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article (59)

Title and authors Publication Year
Pro-inflammatory Actions of Heme and Other Hemoglobin-Derived DAMPs
MT Bozza, V Jeney
Frontiers in immunology 2020
Alternative Complement Pathway Activation Provokes a Hypercoagulable State with Diminished Fibrinolysis:
JM Samuels, JR Coleman, EE Moore, M Bartley, N Vigneshwar, M Cohen, CC Silliman, A Sauaia, A Banerjee
Shock 2020
Paroxysmal Nocturnal Hemoglobinuria
Y Kanakura, T Kinoshita, J Nishimura
Paroxysmal Nocturnal Hemoglobinuria 2017
Eculizumab treatment: stochastic occurrence of C3 binding to individual PNH erythrocytes
M Sica, T Rondelli, P Ricci, MD Angioletti, AM Risitano, R Notaro
Journal of Hematology & Oncology 2017
Extravascular hemolysis and complement consumption in Paroxysmal Nocturnal Hemoglobinuria patients undergoing eculizumab treatment
MS Hidalgo, HM Merinero, A López, J Anter, SP García, FA Gonzalez-Fernández, R Forés, M Lopez-Trascasa, A Villegas, E Ojeda, SR de Córdoba
Immunobiology 2016
Dacie and Lewis Practical Haematology
F Regan
Dacie and Lewis Practical Haematology 2012
A novel approach to preventing the hemolysis of paroxysmal nocturnal hemoglobinuria: both complement-mediated cytolysis and C3 deposition are blocked by a monoclonal antibody specific for the alternative pathway of complement
MA Lindorfer, AW Pawluczkowycz, EM Peek, K Hickman, RP Taylor, CJ Parker
Blood 2010
Eculizumab prevents intravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria and unmasks low-level extravascular hemolysis occurring through C3 opsonization
A Hill, RP Rother, L Arnold, R Kelly, MJ Cullen, SJ Richards, P Hillmen
Haematologica 2010
Paroxysmal Nocturnal Hemoglobinuria: An Historical Overview
CJ Parker
Hematology 2008
PAROXYSMAL NOCTURNAL HEMOGLOBINURIA AND GLYCOSYL PHOSPHATIDYLINOSITOL ANCHORED PROTEINS THAT REGULATE COMPLEMENT
CJ Parker
Clinical & Experimental Immunology 2008
Dacie y Lewis. Hematología Práctica
BJ Bain, N Win
Dacie y Lewis. Hematología Práctica 2008
Acquired haemolytic anaemias
BJ Bain, N Win
Dacie and Lewis Practical Haematology 2006
PNH and the GPI-Linked Proteins
CJ Parker
PNH and the GPI-Linked Proteins 2000
The Human Complement System in Health and Disease
J Ahearn, A Rosengard
The Human Complement System in Health and Disease 1998
Paroxysmal Nocturnal Hemoglobinuria as a Molecular Disease
WF Rosse
Medicine 1997
Paroxysmal Nocturnal Hemoglobinuria as a Molecular Disease:
WF Rosse
Medicine 1997
Membrane Defenses Against Attack by Complement and Perforins
CJ Parker
1992
Paroxysmal nocturnal hemoglobinuria and glycosyl phosphatidylinositol anchored proteins that regulate complement
CJ Parker
Clinical & Experimental Immunology 1991
Paroxysmale nächtliche Hämoglobinurie
P Blaas, S Weber, GM Hänsch, HH Peter
Klinische Wochenschrift 1990
Erythrocytes of patients with paroxysmal nocturnal haemoglobinuria acquire resistance to complement attack by purified 20-kD homologous restriction factor
N Okada, R Harada, H Okada
Clinical & Experimental Immunology 1990
Erythrocytes of patients with paroxysmal nocturnal haemoglobinuria acquire resistance to complement attack by purified 20-kD homologous restriction factor.
Okada N, Harada R, Okada H
Clinical & Experimental Immunology 1990
Complete deficiency of 20 KDa homologous restriction factor (HRF20) and restoration with purified HRF20
N Okada, R Harada, R Taguchi, H Okada
Biochemical and Biophysical Research Communications 1989
Decay-accelerating factor (DAF) on the blood cell membranes in patients with paroxysmal nocturnal haemoglobinuria (PNH): measurement by enzyme-linked immunosorbent assay (ELISA)
H Ninomiya, T Abe, T Shichishima, T Terasawa, T Fujita
British Journal of Haematology 1988
Paroxysmal nocturnal hemoglobinuria type III. Lack of an erythrocyte membrane protein restricting the lysis by C5b-9
GM Hänsch, S Schönermark, D Roelcke
Journal of Clinical Investigation 1987
Specific deposition of complement protein C3b on abnormal PNH erythrocytes permits their separation by partitioning. Possible general approach for isolation of specific cell populations
MK Pangburn, H Walter
Biochimica et Biophysica Acta (BBA) - Biomembranes 1987
Complement
D Vergani
Diabetic Medicine 1986
Characterization of the complement sensitivity of paroxysmal nocturnal hemoglobinuria erythrocytes
CJ Parker, T Wiedmer, PJ Sims, WF Rosse
Journal of Clinical Investigation 1985
Paroxysmal Nocturnal Haemoglobinuria
WF Rosse, CJ Parker
Clinics in Haematology 1985
Abnormality of glycophorin-alpha on paroxysmal nocturnal hemoglobinuria erythrocytes
CJ Parker, CM Soldato, WF Rosse
Journal of Clinical Investigation 1984
The alternative pathway of complement
MK Pangburn, HJ Müller-Eberhard
Springer Seminars in Immunopathology 1984
Deficiency of an erythrocyte membrane protein with complement regulatory activity in paroxysmal nocturnal hemoglobinuria
MK Pangburn, RD Schreiber, HJ Müller-Eberhard
Proceedings of the National Academy of Sciences 1983
Paroxysmal nocturnal hemoglobinuria: deficiency in factor H-like functions of the abnormal erythrocytes
MK Pangburn, RD Schreiber, JS Trombold, HJ Müller-Eberhard
Journal of Experimental Medicine 1983
Lysis of Paroxysmal Nocturnal Hemoglobinuria Erythrocytes by Acid-Activated Serum
G Hänsch, C Hammer, R Jiji, U Rother, M Shin
Immunobiology 1983
Lymphocyte characteristics and function in paroxysmal nocturnal haemoglobinuria
E Vellenga, GJ Ensing, MR Halie, CG Kallenberg, NH Mulder, HO Nieweg, TH The
Blut Zeitschrift für die Gesamte Blutforschung 1983
Increased enzymatic activity of the alternative pathway convertase when bound to the erythrocytes of paroxysmal nocturnal hemoglobinuria
CJ Parker, PJ Baker, WF Rosse
Journal of Clinical Investigation 1982
On the lysis of paroxysmal nocturnal hemoglobinuria erythrocytes by complement: Dual role of C3b
CM Jones, ML Shin, MM Mayer
Blut Zeitschrift für die Gesamte Blutforschung 1982
Complement and Ig Uptake by Erythrocytes in Low Ionic Strength Solutions
IO Szymanski, MG Keegan, PR Odgren
Vox Sanguinis 1981
Contemporary Hematology/Oncology
J LoBue, AS Gordon, R Silber, FM Muggia
1980
Complement Lysis of Human Erythrocytes DIFFERING SUSCEPTIBILITY OF TWO TYPES OF PAROXYSMAL NOCTURNAL HEMOGLOBINURIA CELLS TO C5b-9
CH Packman, SI Rosenfeld, DE Jenkins, PA Thiem, JP Leddy
Journal of Clinical Investigation 1979
An Examination of Complement Proteins on Membranes of Paroxysmal Nocturnal Haemoglobinuria (PNH) and PNH-like Red Cells
N Burapakulsolsri, Y Yuthavong, P Wilairat
British Journal of Haematology 1979
The Low Ionic Strength Reaction of Human Blood: Relationship between the Binding of Serum Immunoglobulin and Complement to Red Blood Cells and Surface Charge of the Cells
TC Hsu, J Steinberg, R Doux, A Sawitsky
British Journal of Haematology 1979
Chido, Rodgers and C4
R Nordhagen, AM Larsen, D Beckers
Vox Sanguinis 1979
Activation of Complement by Stroma from Normal and Paroxysmal Nocturnal Haemoglobinuria Red Cells
G Sandre, R Corrocher, GC Falezza, G Aprili, S Caffi
Scandinavian Journal of Haematology 1978
Paroxysmal Nocturnal Haemoglobinuria in Aplastic Anaemia
WF Rosse
Clinics in Haematology 1978
Mechanism of complement-mediated activation of human blood platelets in vitro: comparison of normal and paroxysmal nocturnal hemoglobinuria platelets
RH Dixon, WF Rosse
Journal of Clinical Investigation 1977
Human lymphocyte complement receptors. Quantitative requirements for C3 of normal and chronic lymphocyte leukemia lymphocytes
GL Logue, HJ Cohen
Journal of Clinical Investigation 1977
Hemolysis by complement and cold-reacting antibodies: Time and temperature requirements
WF Rosse, J Adams, G Logue
American Journal of Hematology 1977
Biological Amplification Systems in Immunology
NK Day, RA Good
1977
Effect of Human Erythrocyte Stromata on Complement Activation
R Corrocher, F Tedesco, P Rabusin, G Sandre
British Journal of Haematology 1975
Studies on the inhibition of C56-initiated lysis (reactive lysis). V. The roleof C567-INH in the regulation of complement-dependent haemolysis initiated by cobravenom factor
B McLeod, TF Lint, P Baker, C Behrends, H Gewurz
Immunology 1975
Mechanisms of Immune Lysis of the Red Cells in Hereditary Erythroblastic Multinuclearity with a Positive Acidified Serum Test and Paroxysmal Nocturnal Hemoglobinuria
WF Rosse, GL Logue, J Adams, JH Crookston
Journal of Clinical Investigation 1974
Hereditary deficiency of the sixth component of complement in man. I. Immunochemical, biologic, and family studies
JP Leddy, MM Frank, T Gaither, J Baum, MR Klemperer
Journal of Clinical Investigation 1974
Studies on the In Vivo Effects of Antibody INTERACTION OF IgM ANTIBODY AND COMPLEMENT IN THE IMMUNE CLEARANCE AND DESTRUCTION OF ERYTHROCYTES IN MAN
JP Atkinson, MM Frank
Journal of Clinical Investigation 1974
The Population of Cells in Paroxysmal Nocturnal Haemoglobinuria of Intermediate Sensitivity to Complement Lysis: Significance and Mechanism of Increased Immune Lysis
WF Rose, JP Adams, AM Thorpe
British Journal of Haematology 1974
Instrumented PVP-Augmented Antiglobulin Tests
TC Hsu, RE Rosenfield, P Rubinstein
Vox Sanguinis 1974
Potentiation of Complement-Dependent Membrane Damage by Ozone
BD Goldstein, LY Lai, R Cuzzi-Spada
Archives of Environmental Health An International Journal 1974
Paroxysmal Nocturnal Hemoglobinuria, a Clue Disease
CF Hinz
New England Journal of Medicine 1973
Paroxysmal Nocturnal Hemoglobinuria: Alternate-Complement-Pathway-Mediated Lysis Induced by Magnesium
JE May, W Rosse, MM Frank
New England Journal of Medicine 1973
Protides of the Biological Fluids
PA Small, RH Waldman
Protides of the Biological Fluids 1969

← Previous 1 2 3 Next →

Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts