The effect of five different reactions which activate complement (antibody activation, reduction in ionic strength, acidification, cobra venom factor (CoF) activation, and inulin activation) upon normal and PNH cells was investigated, using normal serum and serum devoid of the fourth component of complement (C4) activity from patients with hereditary angioneurotic edema (HANE) as a source of complement.
Gerald L. Logue, Wendell F. Rosse, Judith P. Adams
Title and authors | Publication | Year |
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Pro-inflammatory Actions of Heme and Other Hemoglobin-Derived DAMPs
MT Bozza, V Jeney |
Frontiers in immunology | 2020 |
Alternative Complement Pathway Activation Provokes a Hypercoagulable State with Diminished Fibrinolysis:
JM Samuels, JR Coleman, EE Moore, M Bartley, N Vigneshwar, M Cohen, CC Silliman, A Sauaia, A Banerjee |
Shock | 2020 |
Paroxysmal Nocturnal Hemoglobinuria
Y Kanakura, T Kinoshita, J Nishimura |
Paroxysmal Nocturnal Hemoglobinuria | 2017 |
Eculizumab treatment: stochastic occurrence of C3 binding to individual PNH erythrocytes
M Sica, T Rondelli, P Ricci, MD Angioletti, AM Risitano, R Notaro |
Journal of Hematology & Oncology | 2017 |
Extravascular hemolysis and complement consumption in Paroxysmal Nocturnal Hemoglobinuria patients undergoing eculizumab treatment
MS Hidalgo, HM Merinero, A López, J Anter, SP García, FA Gonzalez-Fernández, R Forés, M Lopez-Trascasa, A Villegas, E Ojeda, SR de Córdoba |
Immunobiology | 2016 |
Dacie and Lewis Practical Haematology
F Regan |
Dacie and Lewis Practical Haematology | 2012 |
A novel approach to preventing the hemolysis of paroxysmal nocturnal hemoglobinuria: both complement-mediated cytolysis and C3 deposition are blocked by a monoclonal antibody specific for the alternative pathway of complement
MA Lindorfer, AW Pawluczkowycz, EM Peek, K Hickman, RP Taylor, CJ Parker |
Blood | 2010 |
Eculizumab prevents intravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria and unmasks low-level extravascular hemolysis occurring through C3 opsonization
A Hill, RP Rother, L Arnold, R Kelly, MJ Cullen, SJ Richards, P Hillmen |
Haematologica | 2010 |
Paroxysmal Nocturnal Hemoglobinuria: An Historical Overview
CJ Parker |
Hematology | 2008 |
PAROXYSMAL NOCTURNAL HEMOGLOBINURIA AND GLYCOSYL PHOSPHATIDYLINOSITOL ANCHORED PROTEINS THAT REGULATE COMPLEMENT
CJ Parker |
Clinical & Experimental Immunology | 2008 |
Dacie y Lewis. Hematología Práctica
BJ Bain, N Win |
Dacie y Lewis. Hematología Práctica | 2008 |
Acquired haemolytic anaemias
BJ Bain, N Win |
Dacie and Lewis Practical Haematology | 2006 |
PNH and the GPI-Linked Proteins
CJ Parker |
PNH and the GPI-Linked Proteins | 2000 |
The Human Complement System in Health and Disease
J Ahearn, A Rosengard |
The Human Complement System in Health and Disease | 1998 |
Paroxysmal Nocturnal Hemoglobinuria as a Molecular Disease
WF Rosse |
Medicine | 1997 |
Paroxysmal Nocturnal Hemoglobinuria as a Molecular Disease:
WF Rosse |
Medicine | 1997 |
Membrane Defenses Against Attack by Complement and Perforins
CJ Parker |
1992 | |
Paroxysmal nocturnal hemoglobinuria and glycosyl phosphatidylinositol anchored proteins that regulate complement
CJ Parker |
Clinical & Experimental Immunology | 1991 |
Paroxysmale nächtliche Hämoglobinurie
P Blaas, S Weber, GM Hänsch, HH Peter |
Klinische Wochenschrift | 1990 |
Erythrocytes of patients with paroxysmal nocturnal haemoglobinuria acquire resistance to complement attack by purified 20-kD homologous restriction factor
N Okada, R Harada, H Okada |
Clinical & Experimental Immunology | 1990 |
Erythrocytes of patients with paroxysmal nocturnal haemoglobinuria acquire resistance to complement attack by purified 20-kD homologous restriction factor.
Okada N, Harada R, Okada H |
Clinical & Experimental Immunology | 1990 |
Complete deficiency of 20 KDa homologous restriction factor (HRF20) and restoration with purified HRF20
N Okada, R Harada, R Taguchi, H Okada |
Biochemical and Biophysical Research Communications | 1989 |
Decay-accelerating factor (DAF) on the blood cell membranes in patients with paroxysmal nocturnal haemoglobinuria (PNH): measurement by enzyme-linked immunosorbent assay (ELISA)
H Ninomiya, T Abe, T Shichishima, T Terasawa, T Fujita |
British Journal of Haematology | 1988 |
Paroxysmal nocturnal hemoglobinuria type III. Lack of an erythrocyte membrane protein restricting the lysis by C5b-9
GM Hänsch, S Schönermark, D Roelcke |
Journal of Clinical Investigation | 1987 |
Specific deposition of complement protein C3b on abnormal PNH erythrocytes permits their separation by partitioning. Possible general approach for isolation of specific cell populations
MK Pangburn, H Walter |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 1987 |
Complement
D Vergani |
Diabetic Medicine | 1986 |
Characterization of the complement sensitivity of paroxysmal nocturnal hemoglobinuria erythrocytes
CJ Parker, T Wiedmer, PJ Sims, WF Rosse |
Journal of Clinical Investigation | 1985 |
Paroxysmal Nocturnal Haemoglobinuria
WF Rosse, CJ Parker |
Clinics in Haematology | 1985 |
Abnormality of glycophorin-alpha on paroxysmal nocturnal hemoglobinuria erythrocytes
CJ Parker, CM Soldato, WF Rosse |
Journal of Clinical Investigation | 1984 |
The alternative pathway of complement
MK Pangburn, HJ Müller-Eberhard |
Springer Seminars in Immunopathology | 1984 |
Deficiency of an erythrocyte membrane protein with complement regulatory activity in paroxysmal nocturnal hemoglobinuria
MK Pangburn, RD Schreiber, HJ Müller-Eberhard |
Proceedings of the National Academy of Sciences | 1983 |
Paroxysmal nocturnal hemoglobinuria: deficiency in factor H-like functions of the abnormal erythrocytes
MK Pangburn, RD Schreiber, JS Trombold, HJ Müller-Eberhard |
Journal of Experimental Medicine | 1983 |
Lysis of Paroxysmal Nocturnal Hemoglobinuria Erythrocytes by Acid-Activated Serum
G Hänsch, C Hammer, R Jiji, U Rother, M Shin |
Immunobiology | 1983 |
Lymphocyte characteristics and function in paroxysmal nocturnal haemoglobinuria
E Vellenga, GJ Ensing, MR Halie, CG Kallenberg, NH Mulder, HO Nieweg, TH The |
Blut Zeitschrift für die Gesamte Blutforschung | 1983 |
Increased enzymatic activity of the alternative pathway convertase when bound to the erythrocytes of paroxysmal nocturnal hemoglobinuria
CJ Parker, PJ Baker, WF Rosse |
Journal of Clinical Investigation | 1982 |
On the lysis of paroxysmal nocturnal hemoglobinuria erythrocytes by complement: Dual role of C3b
CM Jones, ML Shin, MM Mayer |
Blut Zeitschrift für die Gesamte Blutforschung | 1982 |
Complement and Ig Uptake by Erythrocytes in Low Ionic Strength Solutions
IO Szymanski, MG Keegan, PR Odgren |
Vox Sanguinis | 1981 |
Contemporary Hematology/Oncology
J LoBue, AS Gordon, R Silber, FM Muggia |
1980 | |
Complement Lysis of Human Erythrocytes DIFFERING SUSCEPTIBILITY OF TWO TYPES OF PAROXYSMAL NOCTURNAL HEMOGLOBINURIA CELLS TO C5b-9
CH Packman, SI Rosenfeld, DE Jenkins, PA Thiem, JP Leddy |
Journal of Clinical Investigation | 1979 |
An Examination of Complement Proteins on Membranes of Paroxysmal Nocturnal Haemoglobinuria (PNH) and PNH-like Red Cells
N Burapakulsolsri, Y Yuthavong, P Wilairat |
British Journal of Haematology | 1979 |
The Low Ionic Strength Reaction of Human Blood: Relationship between the Binding of Serum Immunoglobulin and Complement to Red Blood Cells and Surface Charge of the Cells
TC Hsu, J Steinberg, R Doux, A Sawitsky |
British Journal of Haematology | 1979 |
Chido, Rodgers and C4
R Nordhagen, AM Larsen, D Beckers |
Vox Sanguinis | 1979 |
Activation of Complement by Stroma from Normal and Paroxysmal Nocturnal Haemoglobinuria Red Cells
G Sandre, R Corrocher, GC Falezza, G Aprili, S Caffi |
Scandinavian Journal of Haematology | 1978 |
Paroxysmal Nocturnal Haemoglobinuria in Aplastic Anaemia
WF Rosse |
Clinics in Haematology | 1978 |
Mechanism of complement-mediated activation of human blood platelets in vitro: comparison of normal and paroxysmal nocturnal hemoglobinuria platelets
RH Dixon, WF Rosse |
Journal of Clinical Investigation | 1977 |
Human lymphocyte complement receptors. Quantitative requirements for C3 of normal and chronic lymphocyte leukemia lymphocytes
GL Logue, HJ Cohen |
Journal of Clinical Investigation | 1977 |
Hemolysis by complement and cold-reacting antibodies: Time and temperature requirements
WF Rosse, J Adams, G Logue |
American Journal of Hematology | 1977 |
Biological Amplification Systems in Immunology
NK Day, RA Good |
1977 | |
Effect of Human Erythrocyte Stromata on Complement Activation
R Corrocher, F Tedesco, P Rabusin, G Sandre |
British Journal of Haematology | 1975 |
Studies on the inhibition of C56-initiated lysis (reactive lysis). V. The roleof C567-INH in the regulation of complement-dependent haemolysis initiated by cobravenom factor
B McLeod, TF Lint, P Baker, C Behrends, H Gewurz |
Immunology | 1975 |
Mechanisms of Immune Lysis of the Red Cells in Hereditary Erythroblastic Multinuclearity with a Positive Acidified Serum Test and Paroxysmal Nocturnal Hemoglobinuria
WF Rosse, GL Logue, J Adams, JH Crookston |
Journal of Clinical Investigation | 1974 |
Hereditary deficiency of the sixth component of complement in man. I. Immunochemical, biologic, and family studies
JP Leddy, MM Frank, T Gaither, J Baum, MR Klemperer |
Journal of Clinical Investigation | 1974 |
Studies on the In Vivo Effects of Antibody INTERACTION OF IgM ANTIBODY AND COMPLEMENT IN THE IMMUNE CLEARANCE AND DESTRUCTION OF ERYTHROCYTES IN MAN
JP Atkinson, MM Frank |
Journal of Clinical Investigation | 1974 |
The Population of Cells in Paroxysmal Nocturnal Haemoglobinuria of Intermediate Sensitivity to Complement Lysis: Significance and Mechanism of Increased Immune Lysis
WF Rose, JP Adams, AM Thorpe |
British Journal of Haematology | 1974 |
Instrumented PVP-Augmented Antiglobulin Tests
TC Hsu, RE Rosenfield, P Rubinstein |
Vox Sanguinis | 1974 |
Potentiation of Complement-Dependent Membrane Damage by Ozone
BD Goldstein, LY Lai, R Cuzzi-Spada |
Archives of Environmental Health An International Journal | 1974 |
Paroxysmal Nocturnal Hemoglobinuria, a Clue Disease
CF Hinz |
New England Journal of Medicine | 1973 |
Paroxysmal Nocturnal Hemoglobinuria: Alternate-Complement-Pathway-Mediated Lysis Induced by Magnesium
JE May, W Rosse, MM Frank |
New England Journal of Medicine | 1973 |
Protides of the Biological Fluids
PA Small, RH Waldman |
Protides of the Biological Fluids | 1969 |