In a study of changes in digestive enzymes after massive intestinal resection and the mechanisms by which such changes occur, rats were sacrified 4 wk after removal of the proximal two-thirds of the small intestine. Alterations in the mucosal levels of sucrase, enterokinase, and dipeptide hydrolase (L-leucyl-L-alanine substrate) were examined in the light of associated changes in protein. DNA and wet mucosal weight, measured in standardized gut segments from various regions of intestine.
Denis M. McCarthy, Young S. Kim
Title and authors | Publication | Year |
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Ursodeoxycholic acid promotes intestinal adaptation in a cat model of short bowel syndrome
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Ciba Foundation Symposium 44 - Research and Medical Practice: Their Interaction | 2008 |
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Altered small intestinal absorptive enzyme activities in leptin-deficient obese mice: influence of bowel resection
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Journal of Pediatric Surgery | 2006 |
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Drugs | 2006 |
Glucagon-Like Peptide-2 and Intestinal Adaptation: An Historical and Clinical Perspective
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The Journal of nutrition | 2003 |
Enhancing bowel adaptation in short bowel syndrome
PB Jeppesen, PB Mortensen |
Current Gastroenterology Reports | 2002 |
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A Ukleja, LJ Tammela, MR Lankisch, JS Scolapio |
Current Gastroenterology Reports | 1999 |
Saccharomyces boulardii upgrades cellular adaptation after proximal enterectomy in rats
JP Buts, ND Keyser, S Marandi, D Hermans, EM Sokal, YH Chae, L Lambotte, H Chanteux, PM Tulkens |
Gut | 1999 |
SHORT BOWEL SYNDROME
JS Scolapio, CR Fleming |
Gastroenterology Clinics of North America | 1998 |
Sequential alterations in gut mucosal amino acid and glucose transport after 70% small bowel resection
TP Sarac, AS Seydel, CK Ryan, PQ Bessey, JH Miller, WW Souba, HC Sax |
Surgery | 1996 |
Adaptation of rabbit small intestinal brush-border membrane enzymes after extensive bowel resection
F Swaniker, W Guo, EW Fonkalsrud, T Brown, L Newman, M Ament |
Journal of Pediatric Surgery | 1995 |
Adaptive changes of intestinal cellular retinol-binding protein, type II following jejunum-bypass operation in the rat
S Takase, T Goda, H Shinohara |
Biochimica et Biophysica Acta (BBA) - General Subjects | 1993 |
Age-related changes in duodenal adaptation after distal small bowel resection in rat
K Yoshinaga, J Ishizuka, CM Townsend, JC Thompson |
Digestive Diseases and Sciences | 1993 |
Differentiation status of rat enterocytes after intestinal adaptation to jejunoileal bypass
V Albert, GP Young |
Gut | 1992 |
Degradation of sucrase-isomaltase in the ileum of jejunum-bypassed rats
H Shinohara, T Goda, S Takase |
Biochemical Journal | 1991 |
Effect of oral phytohaemagglutinin intake on cell adaptation in the epithelium of the small intestine of the rat
S Zucoloto, AC Scaramello, FM Lajolo, G Muccillo |
International Journal of Experimental Pathology | 1991 |
The human intestinal response to enteral nutrients: a review
WD Jackson, RJ Grand |
Journal of the American College of Nutrition | 1991 |
The influence of inclusion of either an antibiotic or a probiotic in the diet on the development of digestive enzyme activity in the pig
GK Collington, DS Parker, DG Armstrong |
British Journal of Nutrition | 1990 |
Systemic factors are trophic in bypassed rat small intestine in the absence of luminal contents
V Albert, GP Young, CL Morton, P Robinson, PS Bhathal |
Gut | 1990 |
Changes in serum and intestinal diamine oxidase (DAO) activity after proximal enterectomy in rats: Correlation of DAO activity with mucosal mass parameters
, S Theys, ND Keyser, C Dive |
Digestive Diseases and Sciences | 1989 |
Oral feeding of isolated lectins from red kidney bean stimulates rat small intestinal mucosal DNA synthesis and crypt cell division
H Tajiri, RM Klein, E Lebenthal, |
Digestive Diseases and Sciences | 1988 |
Sodium-dependent d-glucose transport in brush-border membrane vesicles after massive distal small bowel resection in the rat
WC Kwan, GA Quamme, HJ Freeman |
Gastroenterology | 1987 |
Increased activity of digestive enzymes in ileal enterocytes adapting to proximal small bowel resection
M Chaves, MW Smith, RC Williamson |
Gut | 1987 |
The distribution of peptidase activity in the small intestine of sheep
RI Richardson, AR Jouan |
British Journal of Nutrition | 1986 |
The importance of luminal factors in neomucosal growth
JS Thompson, MA Tempero, JL Haun, JA Vanderhoof |
Journal of Surgical Research | 1986 |
Effects of Intraluminal Epidermal Growth Factor on Mucosal Proliferation in the Small Intestine of Adult Rats
MH Ulshen, LE Lyn-Cook, RH Raasch |
Gastroenterology | 1986 |
Early ultrastructural adaptive changes of ileal enterocytes after proximal small bowel resection as determined morphometrically
M Zeitz, H Menge, EO Riecken |
Research in Experimental Medicine | 1985 |
Effect of High Percentage Medium-Chain Triglyceride Diet on Mucosal Adaptation following Massive Bowel Resection in Rats
JA Vanderhoof, CJ Grandjean, SS Kaufman, KT Burkley, DL Antonson |
JPEN. Journal of parenteral and enteral nutrition | 1984 |
Protein digestion and absorption after massive small bowel resection
KJ Curtis, MH Sleisenger, YS Kim |
Digestive Diseases and Sciences | 1984 |
The adaptive response of disaccharidase activities at different sites along the villus epithelium after proximal intestinal resection in the rat
S Gutschmidt, W Kaul, H Menge, EO Riecken |
Research in Experimental Medicine | 1983 |
Effects of Luminal Glucose Versus Nonnutritive Infusates on Jejunal Mass and Absorption in the Rat
GC Richter, GM Levine, YF Shiau |
Gastroenterology | 1983 |
Longitudinal Study of the Human Intestinal Brush Border Membrane Proteins
N Triadou, J Bataille, J Schmitz |
Gastroenterology | 1983 |
Content and Turnover of Rat Intestinal Microvillus Membrane Aminopeptidase
S Miura, A Morita, RH Erickson, YS Kim |
Gastroenterology | 1983 |
Nutritional Aspects of Malabsorption: Short Gut Adaptation
E Weser |
1983 | |
Zinc absorption following massive small-bowel resection in the rat
DL Antonson, JA Vanderhoof |
Digestive Diseases and Sciences | 1982 |
Amino acid and peptide absorption in bypassed jejunum following jejunoileal bypass in rats
AB Garrido, HJ Freeman, YS Kim |
Digestive Diseases and Sciences | 1981 |
Diamine oxidase (histaminase). A circulating marker for rat intestinal mucosal maturation and integrity
GD Luk, TM Bayless, SB Baylin |
Journal of Clinical Investigation | 1980 |
Peptidase Activities in the Functioning Jejunum and Ileum Before and after Jejunoileal Bypass in Morbid Obesity
O Norén, H Sjöström, E Gudmand-Høyer, H Skovbjerg, B Andersen |
Scandinavian Journal of Gastroenterology | 1980 |
Immunoelectrophoretic studies on human small intestinal brush border proteins: cellular alterations in the levels of brush border enzymes after jejunoileal bypass operation
H Skovbjerg, E Gudmand-Hoyer, O Noren, H Sjostrom |
Gut | 1980 |
Untersuchungen zur Spontansolubilisierung mucosaler Peptidhydrolasen des Dünndarms der Ratte
R Mooz, M Friedrich, R Noack |
Food / Nahrung | 1979 |
Enhancement of ileal adaptation by prednisolone after proximal small bowel resection in the rat
J Scott, RM Batt, TJ Peters |
Gut | 1979 |
Enzyme activities and morphological appearance in functioning and excluded segments of the small intestine after shunt operation for obesity
NG Asp, E Gudmand-Høyer, B Andersen, NO Berg |
Gut | 1979 |
Ileal adaptation following proximal intestinal resection is characterized by decreased cellular uptake of amino acid
N Rudo, CW Deveney, LW Way |
Journal of Surgical Research | 1979 |
Nutritional aspects of malabsorption
E Weser |
The American Journal of Medicine | 1979 |
Protein Digestion and Absorption
HL Bleich, ES Boro, MH Sleisenger, YS Kim |
New England Journal of Medicine | 1979 |
Amino acid and peptide absorption after proximal small intestinal resection in the rat
AB Garrido, HJ Freeman, YC Chung, YS Kim |
Gut | 1979 |
Effect of Massive Proximal Small Bowel Resection on Intestinal Brush Border Membrane Proteins in the Dog
M Fehlmann, M Starita-geribaldi, C Thiebaut, P Sudaka |
Archives Of Physiology And Biochemistry | 1978 |
Protein digestion and absorption in the rat
KJ Curtis, YS Kim, JM Perdomo, DB Silk, JS Whitehead |
The Journal of Physiology | 1978 |
Alterations in cell surface membrane components of adapting rat small intestinal epithelium
HJ Freeman, ME Etzler, AB Garrido, YS Kim |
Gastroenterology | 1978 |
An Experimental Model for Studies on the Effects of Food and Digestive Secretions on the Digestive-Absorptive Capacity of Rat Small Intestine
R Ecknauer, RM Clarke, G Feyerabend |
Clinical Chemistry and Laboratory Medicine | 1977 |
Nucleic acid and protein content of rat cecum mucosa in dietary adaptation ? Growth by cellular hyperplasia
K Loeschke, W Resch |
Pflügers Archiv - European Journal of Physiology | 1977 |
Stimulation of Mucosal Growth in the Rat Ileum by Bile and Pancreatic Secretions After Jejunal Resection
E Weser, R Heller, T Tawil |
Gastroenterology | 1977 |
Effects of Oral Versus Intravenous Nutrition on Intestinal Adaptation After Small Bowel Resection in the Dog
EJ Feldman, RH Dowling, J McNaughton, TJ Peters |
Gastroenterology | 1976 |
Epithelial Cell Loss in Remaining Intestine After Small Bowel Resection in the Rat
E Weser, T Tawil |
Gastroenterology | 1976 |
Jejunal Morphology and Mucosal Enzyme Activity Following Intestinal Shunt Operation for Obesity
P Danö, OV Nielsen, M Petri, B Jörgensen |
Scandinavian Journal of Gastroenterology | 1976 |
A one-step l-amino acid oxidase assay for intestinal peptide hydrolase activity
JA Nicholson, YS Kim |
Analytical Biochemistry | 1975 |
Pyrimidine Biosynthetic Enzymes in Rat Intestine After Small Bowel Resection
H Nakayama, E Weser |
Gastroenterology | 1975 |
The Responses of Rat Intestinal Brush Border and Cytosol Peptide Hydrolase Activities to Variation in Dietary Protein Content DIETARY REGULATION OF INTESTINAL PEPTIDE HYDROLASES
JA Nicholson, DM McCarthy, YS Kim |
Journal of Clinical Investigation | 1974 |
Studies on the properties of peptide hydrolases in the brush-border and soluble fractions of small intestinal mucosa of rat and man
YS Kim, YW Kim, MH Sleisenger |
Biochimica et Biophysica Acta (BBA) - Enzymology | 1974 |
Intestinal Peptide Hydrolases: Peptide and Amino Acid Absorption
YS Kim, JA Nicholson, KJ Curtis |
Medical Clinics of North America | 1974 |