Myelin in femoral nerve segments obtained at autopsy was isolated quantitatively by a series of discontinuous and continuous flotation procedures. The total amount of myelin isolated from these nerves was expressed as the sum of cholesterol, glycolipid, phospholipid, and protein and averaged 2.6±0.4 mg/g in a group aged 60-77 yr compared with 10.8±1.9 mg/g of nerve in a group aged 35-58 yr. The lower value in the older group remained apparent whether the myelin content was related to the whole nerve segment, its unit length or weight. This indicates that the decrease is an absolute one, not related to a change with aging in the nonmyelin content of nerve.
Norton Spritz, Harbhajan Singh, Barbara Geyer
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Roles for PMP22 in Schwann Cell Cholesterol Homeostasis in Health and Disease
Stefanski KM, Wilkinson MC, Sanders CR |
Biochemical Society transactions | 2024 |
Is MS affecting the CNS only?: Lessons from clinic to myelin pathophysiology
E Oudejans, A Luchicchi, EM Strijbis, JJ Geurts, AM van Dam |
Neurology: Neuroimmunology & Neuroinflammation | 2020 |
Quantified Morphology of the Cervical and Subdiaphragmatic Vagus Nerves of Human, Pig, and Rat
NA Pelot, GB Goldhagen, JE Cariello, ED Musselman, KA Clissold, JA Ezzell, WM Grill |
Frontiers in neuroscience | 2020 |
Quantified Morphology of the Cervical and Subdiaphragmatic Vagus Nerves of Human, Pig, and Rat.
Pelot NA, Goldhagen GB, Cariello JE, Musselman ED, Clissold KA, Ezzell JA, Grill WM |
Frontiers in neuroscience | 2020 |
The Evolution of Myelin: Theories and Application to Human Disease
L Knowles |
Journal of Evolutionary Medicine | 2017 |
Comunicación entre células gliales y neuronas II. Células gliales que forman mielina
A Martínez-Gómez |
Medicina e Investigación | 2014 |
Handbook of Neurochemistry and Molecular Neurobiology
VH Routh, JJ McArdle, NM Sanders, Z Song, R Wang |
Handbook of Neurochemistry and Molecular Neurobiology | 2007 |
Lipides du nerf périphérique
N Baumann, J Aubry |
EMC - Neurologie | 2004 |
Smith-Lemli-Opitz syndrome and other sterol disorders among Finns with developmental disabilities
MJ Nissinen, H Gylling, M Kaski, P Tammisto, S Mieskonen, J Ignatius, TA Miettinen |
Journal of Laboratory and Clinical Medicine | 2000 |
Membrane lipids of human peripheral nerve and spinal cord
L Svennerholm, K Boström, P Fredman, B Jungbjer, JE Månsson, BM Rynmark |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1992 |
Neuropathies
S Mitchell |
Reviews in Clinical Gerontology | 1991 |
Myelination and Demyelination
SU Kim |
1989 | |
Slow recovery of the fatty acid composition of sciatic nerve in rats fed a diet initially low in n−3 fatty acids
JM Bourre, A Youyou, G Durand, G Pascal |
Lipids | 1987 |
Slow recovery of the fatty acid composition of sciatic nerve in rats fed a diet initially low in n-3 fatty acids.
Bourre JM, Youyou A, Durand G, Pascal G |
Lipids | 1987 |
Fatty Acid Composition of Endoneurium and Perineurium from Adult Rat Sciatic Nerve
C Fressinaud, M Rigaud, JM Vallat |
Journal of Neurochemistry | 1986 |
Subcellular Fractionation of Rat Sciatic Nerve and Specific Localization of Ganglioside LM1 in Rat Nerve Myelin
KH Chou, CE Nolan, FB Jungalwala |
Journal of Neurochemistry | 1985 |
Myelin
P Morell |
1984 | |
Loss of intracortical myelinated fibers: A distinctive age-related alteration in the human striate area
P Lintl, H Braak |
Acta Neuropathologica | 1983 |
Metabolism in the Nervous System
A Lajtha |
1983 | |
Loss of intracortical myelinated fibers: a distinctive age-related alteration in the human striate area.
Lintl P, Braak H |
Acta Neuropathologica | 1983 |
Preparation of cell-free extracellular matrix from human peripheral nerve
PC Johnson, RC Duhamel, E Meezan, K Brendel |
Muscle & Nerve | 1982 |
Peripheral Nerve Phospholipid Composition: Development in Normal Nerve and Age-Dependent Changes in Wallerian Degenerated Nerve
JH Hofteig, PN Vo, AJ Yates, KS Leon |
Journal of Neurochemistry | 1982 |
Analysis of distribution of rat sciatic nerve protein among soluble, insoluble, and myelin subfractions
RC Wiggins, GN Fuller |
Neurochemical Research | 1981 |
Correlative biochemical and morphological studies of myelination in human ontogenesis
I Niebrój-Dobosz, A Fidziańska, J Rafaŀowska, E Sawicka |
Acta Neuropathologica | 1980 |
Correlative biochemical and morphological studies of myelination in human ontogenesis. II. Myelination of the nerve roots.
Niebrój-Dobosz I, Fidziańska A, Rafałwska J, Sawicka E |
Acta Neuropathologica | 1980 |
Endoneurial lipid composition of normal human sural nerve
MJ Brown, M Iwamori, Y Kishimoto, SM Ostroff, HW Moser, AK Asbury |
Annals of Neurology | 1979 |
FROG SCIATIC NERVE MYELIN: A CHEMICAL CHARACTERIZATION
ME Smith, BM Curtis |
Journal of Neurochemistry | 1979 |
Analysis of the major lipid classes in human peripheral nerve biopsies
S Pollet, JJ Hauw, JC Turpin, FL Saux, R Escourolle, N Baumann |
Journal of the Neurological Sciences | 1979 |
A comparative study of the polypeptides of mammalian peripheral nerve myelin
H Singh, I Silberlicht, IJ Singh |
Brain Research | 1978 |
Protein kinase associated with peripheral nerve myelin. 1. Phosphorylation of endogenous myelin proteins and exogenous substrates
H Singh, N Spritiz, I Silberlicht |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 1976 |
Characterization of myelin of chick sciatic nerve during development
MR Oulton, C Mezei |
Journal of lipid research | 1976 |
Metabolism of peripheral nerve myelin in experimental diabetes
N Spritz, H Singh, B Marinan |
Journal of Clinical Investigation | 1975 |
CHANGES IN THE SCIATIC NERVE OF THE RABBIT AND ITS TISSUE CONSTITUENTS DURING DEVELOPMENT
AJ Yates, JR Wherrett |
Journal of Neurochemistry | 1974 |
Polypeptide components of myelin from rat peripheral nerve
H Singh, N Spritz |
Biochimica et Biophysica Acta (BBA) - Protein Structure | 1974 |