Studies of Two Subpopulations of Human Lymphocytes Differing in Responsiveness to Concanavalin A

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Abstract

We have identified two populations of human lymphocytes differing in responsiveness to the plant mitogen concanavalin A (Con-A). When peripheral blood lymphocytes are passed through a nylon column a population of lymphocytes highly responsive to Con-A adheres to the fibers while a second population of cells relatively unresponsive to Con-A emerges from the column. The untreated peripheral blood lymphocytes are termed “unfiltered” cells while the lymphocytes which pass through the column are termed “filtered” cells.

Authors

David Boldt, Sister Ann Marie Skinner, Stuart Kornfeld