Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Citations to this article

A collagenolytic system produced by primary cultures of rheumatoid nodule tissue
Edward D. Harris Jr.
Edward D. Harris Jr.
Published November 1, 1972
Citation Information: J Clin Invest. 1972;51(11):2973-2976. https://doi.org/10.1172/JCI107122.
View: Text | PDF
Concise Publication

A collagenolytic system produced by primary cultures of rheumatoid nodule tissue

  • Text
  • PDF
Abstract

A collagenase and a neutral protease have been insolated and characterized from primary cultures obtained from rheumatoid subcutaneous nodules. Release of both active enzymes was maximal between the 3rd and 7th days of culture and was stimulated by the presence of small amounts of colchicine (0.1 μg/ml) added to the culture medium.

Authors

Edward D. Harris Jr.

×

Total citations by year

Year: 2019 2009 1994 1991 1990 1989 1987 1986 1983 1982 1981 1980 1979 1978 1977 1976 1975 1974 1973 1972 1969 1964 Total
Citations: 1 2 2 1 1 1 1 1 4 1 1 1 1 2 3 2 5 8 1 1 1 1 42
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article (42)

Title and authors Publication Year
Matrix metalloproteinases and inhibitors in dentistry
GJ Boelen, L Boute, J dHoop, M EzEldeen, I Lambrichts, G Opdenakker
Clinical Oral Investigations 2019
Mesenteric rheumatoid nodules masquerading as an intra-abdominal malignancy: a case report and review of the literature
S Thinda, JS Tomlinson
World journal of surgical oncology 2009
Kelley's Textbook of Rheumatology
J Degroot, AM Zuurmond, PP Tak
Kelley's Textbook of Rheumatology 2009
Immunology of the Connective Tissue Diseases
GS Panayi
1994
The Sclera
CS Foster, MS de la Maza
1994
Immunopathology of subcutaneous rheumatoid nodules
OJ Mellbye, O Forre, TE Mollnes, L Kvarnes
Annals of the rheumatic diseases 1991
The rheumatoid nodule
M Ziff
Arthritis & Rheumatism 1990
Immunological and immunohistochemical analysis of rheumatoid nodules
N Miyasaka, K Sato, K Yamamoto, M Goto, K Nishioka
Annals of the rheumatic diseases 1989
A mononuclear phagocyte subset associated with cell necrosis in rheumatoid nodules: Identification with monoclonal antibody 5.5
DG Palmer, N Hogg, CA Allen, J Highton, PA Hessian
Clinical Immunology and Immunopathology 1987
Rheumatoid nodulosis: Report of a case with evidence of intraosseous rheumatoid granuloma
A Morales-Piga, A Elena-Ibañez, AC Zea-Mendoza, A Rocamora-Ripoll, J Beltrán-Gutiérrez
Arthritis & Rheumatism 1986
Evaluation of pathophysiology and drug effects on rheumatoid arthritis
ED Harris
The American Journal of Medicine 1983
Advances in Radiation Biology
SK Calderwood, JA Dickson
Advances in Radiation Biology 1983
Are rheumatoid nodules caused by vasculitis? A study of 13 early cases
JJ Rasker, FC Kuipers
Annals of the rheumatic diseases 1983
Rheumatologie A: Allgemeiner Teil
GL Bach, R Czurda, JM Engel, O Fischedick, M Franke, K Meythaler, H Müller-Faßbender, P Pfannenstiel, N Thumb, D Wessinghage, H Mathies, H Greiling, A Gressner, K Kleesiek
1983
Purification of human neutrophil collagenase and production of a monospecific antiserum
P Christner, D Damato, M Reinhardt, W Abrams
Biochemistry 1982
Purification and properties of a gelatin-specific neutral protease from human skin
JL Seltzer, SA Adams, GA Grant, AZ Eisen
The Journal of biological chemistry 1981
Macrophage Factor that Induces Neutral Protease Secretion by Normal Rabbit Chondrocytes. Studies of Some Properties and Effects on Metabolism of Chondrocytes
K DESHMUKH-PHADKE, S NANDA, K LEE
European Journal of Biochemistry 1980
COLLAGEN IN CUTANEOUS DISEASES
EA Bauer, J Uitto
International Journal of Dermatology 1979
Collagenase production by cultures containing multinucleated cells derived from synovial fibroblasts
CE Brinckerhoff, ED Harris
Arthritis & Rheumatism 1978
The simultaneous release by bone explants in culture and the parallel activation of procollagenase and of a latent neutral proteinase that degrades cartilage proteoglycans and denatured collagen
G Vaes, Y Eeckhout, G Lenaers-Claeys, C François-Gillet, JE Druetz
Biochemical Journal 1978
Localization of collagenase in human middle ear cholesteatoma
M Abramson, CC Huang
The Laryngoscope 1977
Intracellular collagen fibers at the pannus-cartilage junction in rheumatoid arthritis
ED Harris, AM Glauert, AH Murley
Arthritis & Rheumatism 1977
Endogenous Activation of Latent Collagenase by Rheumatoid Synovial Cells: Evidence for a Role of Plasminogen Activator
Z Werb, CL Mainardi, CA Vater, ED Harris
New England Journal of Medicine 1977
Recent insights into the pathogenesis of the proliferative lesion in rheumatoid arthritis
ED Harris
Arthritis & Rheumatism 1976
Biochemistry of Collagen
GN Ramachandran, AH Reddi
1976
COLLAGENASE PRODUCTION BY HUMAN SYNOVIAL TISSUES
SM Krane
Annals of the New York Academy of Sciences 1975
Review of articular cartilage collagen research
JM Lane, C Weiss
Arthritis & Rheumatism 1975
Purification of Rheumatoid Synovial Collagenase and Its Action on Soluble and Insoluble Collagen
DE WOOLLEY, RW GLANVILLE, MJ CROSSLEY, JM EVANSON
European Journal of Biochemistry 1975
Extracellular Matrix Influences on Gene Expression
E Harper, CM Chesney, RW Colman
Extracellular Matrix Influences on Gene Expression 1975
D-Penicillamine in Rheumatoid Arthritis
AG Mowat, E Huskisson
Clinics in rheumatic diseases 1975
The Collagenase of Carrageenin Granuloma
A Pardo, R Pérez-Tamayo
Connective Tissue Research 1974
A specific collagenase from rabbit fibroblasts in monolayer culture
Z Werb, MC Burleigh
Biochemical Journal 1974
Stimulation by endocytosis of the secretion of collagenase and neutral proteinase from rabbit synovial fibroblasts
Z Werb, JJ Reynolds
Journal of Experimental Medicine 1974
Synovialzellkulturen für die Erforschung der Pathogenese der Rheumatoiden Arthritis
W Mohr, G Beneke
Beiträge zur Pathologie 1974
Collagenases
ED Harris, SM Krane
New England Journal of Medicine 1974
The Influence of Temperature and Fibril Stability on Degradation of Cartilage Collagen by Rheumatoid Synovial Collagenase
ED Harris, PA McCroskery
New England Journal of Medicine 1974
Animal collagenases: Specificity of action, and structures of the substrate cleavage site
J Gross, E Harper, ED Harris, PA McCroskery, JH Highberger, C Corbett, AH Kang
Biochemical and Biophysical Research Communications 1974
Presence of a gelatin-specific proteinase and its latent form in human leucocytes
I Sopata, AM Dancewicz
Biochimica et Biophysica Acta (BBA) - Enzymology 1974
Gelatin: A Poor Substrate for a Mammalian Collagenase
PA McCroskery, S Wood, ED Harris
Science 1973
Collagenase in carcinoma cells
ED Harris, CS Faulkner, S Wood
Biochemical and Biophysical Research Communications 1972
Protides of the Biological Fluids
PA Small, RH Waldman
Protides of the Biological Fluids 1969
International Review of Connective Tissue Research
JP Ayer
International Review of Connective Tissue Research 1964

← Previous 1 2 Next →

Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts