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Citations to this article

Functional Aspects of a Second Mechanism of Candidacidal Activity by Human Neutrophils
Robert I. Lehrer
Robert I. Lehrer
Published October 1, 1972
Citation Information: J Clin Invest. 1972;51(10):2566-2572. https://doi.org/10.1172/JCI107073.
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Research Article

Functional Aspects of a Second Mechanism of Candidacidal Activity by Human Neutrophils

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Abstract

We tested the ability of human neutrophils to kill five Candida species and the yeast Torulopsis glabrata. C. parapsilosis and C. pseudotropicalis were found to be killed readily by normal and myeloperoxidase-deficient neutrophils and were selected to probe the myeloperoxidase-independent fungicidal mechanisms of the neutrophil.

Authors

Robert I. Lehrer

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Total citations by year

Year: 2022 2019 2018 2016 2015 2014 2013 2011 2008 2006 2001 1999 1994 1993 1992 1991 1990 1989 1988 1986 1985 1984 1983 1982 1981 1980 1979 1978 1977 1976 1975 1974 1973 Total
Citations: 1 2 1 1 1 2 1 1 1 1 1 1 3 2 3 2 5 3 4 2 4 2 4 3 3 5 2 4 7 4 6 1 1 84
Citation information
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Citations to this article (84)

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Candida parapsilosis : from Genes to the Bedside
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ERG11 couples oxidative stress adaptation, hyphal elongation and virulence in Candida albicans
YQ Wu, MY Wu, YY Wang, YS Chen, J Gao, CM Ying
FEMS Yeast Research 2018
Impaired killing of Candida albicans by granulocytes mobilized for transfusion purposes: a role for granule components
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Beyond Candida albicans: Mechanisms of immunity to non-albicans Candida species
N Whibley, SL Gaffen
Cytokine 2015
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Mononuclear Phagocytes
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1990
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Systemic candidosis in beige mice
A Baghian, KW Lee
Medical Mycology 1989
Oral Candida albicans isolates from nonhospitalized normal carriers, immunocompetent hospitalized patients, and immunocompromised patients with or without acquired immunodeficiency syndrome
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Pentamidine isethionate-induced neutrophil dysfunction
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Annals of Tropical Medicine and Parasitology 1988
Myeloperoxidase Deficiency
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Host-Parasite Relationship in Opportunistic Mycoses
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Critical Reviews in Microbiology 1986
Metabolic activity of phagocytes in experimental sporotrichosis
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Defensins. Natural peptide antibiotics of human neutrophils
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Activity of rabbit leukocyte peptides against Candida albicans
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Pathogenicity of morphological and auxotrophic mutants of Candida albicans in experimental infections
MG Shepherd
Infection and immunity 1985
Studies on Granulocyte Functions in Patients with Chronic Myeloid Leukemia
PN Anklesaria, SH Advani, AN Bhisey
TUMORI 1985
Variability in expression of a cell surface determinant on Candida albicans as evidenced by an agglutinating monoclonal antibody
DL Brawner, JE Cutler
Infection and immunity 1984
Regulation of Leukocyte Function
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1984
Combined neutrophil and T-cell deficiency
E Silverman, J Bargman
The American Journal of Medicine 1983
The enhancement of eosinophil function by lymphocyte supernatants
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Enhanced antibody responses induced by Candida albicans in mice
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Microbicidal Activity of Bone Marrow Cells. Augmentation of Candida Killing Activity of the Cells by Culturing with Fibroblast Conditioned Medium
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Iodination catalyzed by the xanthine oxidase system: role of hydroxyl radicals
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Effects of surgery on neutrophil granulocyte function
H El-Maallem, J Fletcher
Infection and immunity 1981
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A Pagani, R Spalla, FA Ferrari, M Duse, L Lenzi, U Bretz, M Baggiolini, AG Siccardi
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Immunology of Human Infection
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In vitro phagocytosis of Candida albicans by peritoneal mouse macrophages
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Immunity to Candida albicans
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Oxidativer Metabolismus von Phagozyten: Physikochemische Grundlagen und klinische Relevanz
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Klinische Wochenschrift 1980
Effect of bilirubin on the fungicidal capacity of human neutrophils
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Mechanisms of Attachment of Neutrophils to Candida albicans Pseudohyphae in the Absence of Serum, and of Subsequent Damage to Pseudohyphae by Microbicidal Processes of Neutrophils In Vitro
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Phagocytosis: A Review
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The in vitro interactions of candida albicans with nonspecific serum proteins
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Susceptibility of lipopolysaccharide mutants to the bactericidal action of human neutrophil lysosomal fractions
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Fungicidal properties of a chymotrypsin-like cationic protein from human neutrophils: adsorption to Candida parapsilosis
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Microbial surfaces in relation to pathogenicity
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A simple microscopic method for identifying and quantitating phagocytic cells in vitro
J Patterson-Delafield, RI Lehrer
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Disseminated candidiasis in a previously healthy girl: Implication of a leukocyte candidacidal defect
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Clinical Immunology and Immunopathology 1977
The Clinical and Laboratory Diagnosis of Chronic Granulomatous Disease of Childhood
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The Year in Hematology
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Defective Neutrophil Function in Chronic Granulocytic: Leukaemia
H EL-MAALEM, J Fletcher
British Journal of Haematology 1976
Function of Granulocytes with Deficient Myeloperoxidase-Mediated Iodination in a Patient with Generalized Pustular Psoriasis
O Stendahl, S Lindgren
Scandinavian Journal of Haematology 1976
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Revue Française d'Allergologie et d'Immunologie Clinique 1976
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Clinics in Haematology 1976
The fungicidal mechanisms of human monocytes. I. Evidence for myeloperoxidase-linked and myeloperoxidase-independent candidacidal mechanisms
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Antibacterial activity of cationic proteins from human granulocytes
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The American Journal of Medicine 1974
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