Free fatty acid oxidation and carnitine levels in diphtheritic guinea pig myocardium

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Abstract

Previous studies from this laboratory and by Wittels and Bressler have suggested that myocardial carnitine depletion and an accompanying decrease in fatty acid oxidation may contribute to the myocardial disease associated with diphtheria. In addition, administration of carnitine was found to prolong survival of diphtheritic guinea pigs and improve ventricular function in diphtheritic dogs.

Authors

David R. Challoner, Hans G. Prols